1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one	go back to main search page
Accession:	CHEBI:84002	browse the term
Definition:	A member of the class of triazoles that is 1-hydroxy-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one in which the hydroxyl hydrogen is replaced by a 4-chlorophenyl group.
Synonyms:	exact_synonym:	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-one
	related_synonym:	Formula=C14H16ClN3O2; InChI=1S/C14H16ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,13H,1-3H3; InChIKey=WURBVZBTWMNKQT-UHFFFAOYSA-N; SMILES=CC(C)(C)C(=O)C(Oc1ccc(Cl)cc1)n1cncn1
	xref:	LINCS:LSM-4424; PPDB:648

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Genes (630)

triadimefon

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acetoacetyl-CoA synthetase

increases expression

triadimefon results in increased expression of AACS mRNA

NCBI chr12:31,113,098...31,156,411
Ensembl chr12:31,113,098...31,160,954

G

ATP binding cassette subfamily B member 1A

decreases expression
increases expression

triadimefon results in decreased expression of ABCB1 mRNA
triadimefon results in increased expression of ABCB1 mRNA

NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709

G

ATP binding cassette subfamily B member 4

decreases expression

triadimefon results in decreased expression of ABCB4 mRNA

NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202

G

ATP binding cassette subfamily B member 9

increases expression

triadimefon results in increased expression of ABCB9 mRNA

NCBI chr12:32,499,213...32,531,932
Ensembl chr12:32,499,225...32,531,931

G

ATP binding cassette subfamily C member 3

increases expression

triadimefon results in increased expression of ABCC3 mRNA

NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595

G

ATP binding cassette subfamily C member 4

increases expression

triadimefon results in increased expression of ABCC4 mRNA

NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283

G

ATP binding cassette subfamily G member 1

increases expression

triadimefon results in increased expression of ABCG1 mRNA

NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948

G

ATP binding cassette subfamily G member 5

increases expression

triadimefon results in increased expression of ABCG5 mRNA

NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563

G

ABI family member 3 binding protein

decreases expression

triadimefon results in decreased expression of ABI3BP mRNA

NCBI chr11:43,912,187...44,128,888
Ensembl chr11:43,913,043...44,128,929

G

acyl-CoA binding domain containing 3

increases expression

triadimefon results in increased expression of ACBD3 mRNA

NCBI chr13:92,455,813...92,484,556
Ensembl chr13:92,455,655...92,483,380

G

acyl-CoA oxidase-like

decreases expression

triadimefon results in decreased expression of ACOXL mRNA

NCBI chr 3:115,061,069...115,367,032
Ensembl chr 3:115,061,060...115,364,686

G

acid phosphatase 3

increases expression

triadimefon results in increased expression of ACP3 mRNA

NCBI chr 8:104,905,570...104,956,146
Ensembl chr 8:104,905,586...104,954,236

G

acyl-CoA synthetase long-chain family member 3

increases expression

triadimefon results in increased expression of ACSL3 mRNA

NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627

G

actin alpha 2, smooth muscle

decreases expression

triadimefon results in decreased expression of ACTA2 mRNA

NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554

G

actin, beta

decreases expression

triadimefon results in decreased expression of ACTB mRNA

NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877

G

actin gamma 2, smooth muscle

decreases expression

triadimefon results in decreased expression of ACTG2 mRNA

NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465

G

actinin, alpha 1

decreases expression

triadimefon analog results in decreased expression of ACTN1 mRNA; triadimefon results in decreased expression of ACTN1 mRNA

NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251

G

ADAM metallopeptidase with thrombospondin type 1 motif, 1

increases expression

triadimefon results in increased expression of ADAMTS1 mRNA

NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103

G

adenosine deaminase, RNA-specific, B1

increases expression

triadimefon results in increased expression of ADARB1 mRNA

NCBI chr20:11,222,569...11,350,854
Ensembl chr20:11,222,583...11,350,852

G

adhesion G protein-coupled receptor D1

decreases expression

triadimefon results in decreased expression of ADGRD1 mRNA

NCBI chr12:27,488,908...27,603,714
Ensembl chr12:27,488,908...27,603,696

G

adhesion G protein-coupled receptor F5

increases expression

triadimefon results in increased expression of ADGRF5 mRNA

NCBI chr 9:17,517,596...17,624,107
Ensembl chr 9:17,520,009...17,623,968

G

adhesion G protein-coupled receptor G6

decreases expression

triadimefon results in decreased expression of ADGRG6 mRNA

NCBI chr 1:8,812,889...8,954,239
Ensembl chr 1:8,812,904...8,954,123

G

adhesion G protein-coupled receptor L2

affects expression

triadimefon affects the expression of ADGRL2 mRNA

NCBI chr 2:237,696,055...238,327,141
Ensembl chr 2:237,696,056...238,327,141

G

adhesion G protein-coupled receptor V1

decreases expression

triadimefon results in decreased expression of ADGRV1 mRNA

NCBI chr 2:11,331,434...11,911,713
Ensembl chr 2:11,331,442...11,911,688

G

alcohol dehydrogenase 1C (class I), gamma polypeptide

increases expression

triadimefon results in increased expression of ADH1 mRNA

NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892

G

alcohol dehydrogenase 4 (class II), pi polypeptide

decreases expression

triadimefon results in decreased expression of ADH4 mRNA

NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591

G

alcohol dehydrogenase, iron containing, 1

decreases expression

triadimefon results in decreased expression of ADHFE1 mRNA

NCBI chr 5:9,705,966...9,732,580
Ensembl chr 5:9,705,970...9,732,517

G

adenosine A2B receptor

decreases expression

triadimefon results in decreased expression of ADORA2B mRNA

NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772

G

angiotensin II receptor, type 1a

decreases expression

triadimefon results in decreased expression of AGTR1 mRNA; triadimefon results in decreased expression of AGTR1 protein

NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946

G

AT hook containing transcription factor 1

decreases expression

triadimefon results in decreased expression of AHCTF1 mRNA

NCBI chr13:91,481,936...91,536,391
Ensembl chr13:91,481,936...91,536,391

G

aryl hydrocarbon receptor

decreases activity

triadimefon results in decreased activity of AHR protein

NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568

G

aryl-hydrocarbon receptor repressor

affects expression

triadimefon affects the expression of AHRR mRNA

NCBI chr 1:28,993,634...29,088,673
Ensembl chr 1:28,993,634...29,088,673

G

aldo-keto reductase family 7 member A3

increases expression

triadimefon results in increased expression of AKR7A3 mRNA

NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394

G

AKT serine/threonine kinase 1

decreases phosphorylation

triadimefon results in decreased phosphorylation of AKT1 protein

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

5'-aminolevulinate synthase 1

increases expression

triadimefon results in increased expression of ALAS1 mRNA

NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917

G

aldehyde dehydrogenase 1 family, member A1

increases expression

triadimefon results in increased expression of ALDH1A1 mRNA

PMID:17178689 PMID:19409404 PMID:19423681

NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961

G

aldehyde dehydrogenase 4 family, member A1

decreases expression

triadimefon results in decreased expression of ALDH4A1 mRNA

NCBI chr 5:151,880,002...151,905,491
Ensembl chr 5:151,830,701...151,925,345

G

alkB homolog 6

increases expression

triadimefon results in increased expression of ALKBH6 mRNA

NCBI chr 1:85,563,511...85,568,977
Ensembl chr 1:85,563,592...85,568,973

G

alpha-kinase 2

decreases expression

triadimefon results in decreased expression of ALPK2 mRNA

NCBI chr18:58,775,603...58,906,150
Ensembl chr18:58,775,605...58,906,258

G

angiogenin, ribonuclease A family, member 2

decreases expression

triadimefon results in decreased expression of ANG2 mRNA

NCBI chr15:24,398,330...24,415,909
Ensembl chr15:24,398,419...24,398,922

G

ankyrin repeat domain 1

decreases expression

triadimefon results in decreased expression of ANKRD1 mRNA

NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919

G

ankyrin repeat domain 10

affects expression

triadimefon affects the expression of ANKRD10 mRNA

NCBI chr16:77,866,489...77,889,745
Ensembl chr16:77,864,261...77,889,745

G

ankyrin repeat domain 34B

decreases expression

triadimefon results in decreased expression of ANKRD34B mRNA

NCBI chr 2:23,651,083...23,668,041
Ensembl chr 2:23,651,474...23,668,030

G

anoctamin 4

decreases expression

triadimefon results in decreased expression of ANO4 mRNA

NCBI chr 7:23,329,015...23,738,423
Ensembl chr 7:23,329,070...23,738,434

G

annexin A1

decreases expression

triadimefon results in decreased expression of ANXA1 mRNA

NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343

G

annexin A3

decreases expression

triadimefon results in decreased expression of ANXA3 mRNA

NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617

G

adaptor related protein complex 3 subunit beta 1

increases expression

triadimefon results in increased expression of AP3B1 mRNA

NCBI chr 2:25,600,069...25,800,937
Ensembl chr 2:25,600,040...25,800,935

G

amyloid P component, serum

increases expression

triadimefon results in increased expression of APCS mRNA

NCBI chr13:85,373,219...85,374,195
Ensembl chr13:85,373,220...85,374,298

G

apolipoprotein A4

decreases expression

triadimefon results in decreased expression of APOA4 mRNA

PMID:16643972 PMID:19423681

NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469

G

amyloid beta precursor protein

increases expression

triadimefon results in increased expression of APP mRNA

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

G

aquaporin 1

decreases expression

triadimefon results in decreased expression of AQP1 mRNA

NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690

G

androgen receptor

multiple interactions
decreases activity

triadimefon inhibits the reaction [Metribolone results in increased activity of AR protein]
triadimefon results in decreased activity of AR protein

PMID:18324785 PMID:21251949

NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925

G

arginase 1

increases expression

triadimefon results in increased expression of ARG1 mRNA

NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422

G

aryl hydrocarbon receptor nuclear translocator 2

increases expression

triadimefon results in increased expression of ARNT2 mRNA

NCBI chr 1:138,236,235...138,392,868
Ensembl chr 1:138,189,940...138,393,153

G

ankyrin repeat and SOCS box-containing 1

decreases expression

triadimefon results in decreased expression of ASB1 mRNA

NCBI chr 9:92,120,332...92,140,790
Ensembl chr 9:92,120,306...92,136,376

G

anti-silencing function 1B histone chaperone

affects expression

triadimefon affects the expression of ASF1B mRNA

NCBI chr19:24,181,024...24,195,604
Ensembl chr19:24,181,028...24,195,549

G

asporin

decreases expression

triadimefon results in decreased expression of ASPN mRNA

NCBI chr17:15,079,910...15,104,369
Ensembl chr17:15,080,639...15,104,041

G

activating transcription factor 5

decreases expression

triadimefon results in decreased expression of ATF5 mRNA

NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707

G

autophagy related 16-like 2

increases expression

triadimefon results in increased expression of ATG16L2 mRNA

NCBI chr 1:155,687,386...155,703,419
Ensembl chr 1:155,684,564...155,703,420

G

ATPase phospholipid transporting 8B1

decreases expression

triadimefon results in decreased expression of ATP8B1 mRNA

NCBI chr18:58,016,382...58,157,213
Ensembl chr18:58,018,268...58,157,396

G

Beta-1,3-galactosyltransferase 2

decreases expression

triadimefon results in decreased expression of B3GALT2 mRNA

NCBI chr13:55,389,406...55,398,419
Ensembl chr13:55,389,406...55,398,419

G

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7

affects expression

triadimefon affects the expression of B3GNT7 mRNA

NCBI chr 9:86,956,220...86,960,171
Ensembl chr 9:86,956,220...86,960,170

G

BAR/IMD domain containing adaptor protein 2

decreases expression

triadimefon results in decreased expression of BAIAP2 mRNA

NCBI chr10:105,223,065...105,290,130
Ensembl chr10:105,223,090...105,290,134

G

BRCA1 associated RING domain 1

increases expression

triadimefon results in increased expression of BARD1 mRNA

NCBI chr 9:72,616,070...72,694,553
Ensembl chr 9:72,623,155...72,694,265

G

BCL2 associated X, apoptosis regulator

affects expression

triadimefon affects the expression of BAX mRNA

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

branched chain keto acid dehydrogenase E1 subunit alpha

decreases expression

triadimefon results in decreased expression of BCKDHA mRNA

NCBI chr 1:81,138,946...81,167,765
Ensembl chr 1:81,138,947...81,167,862

G

baculoviral IAP repeat-containing 5

increases expression
multiple interactions

triadimefon results in increased expression of BIRC5 mRNA
NR1H3 gene mutant form inhibits the reaction [triadimefon results in increased expression of BIRC5 mRNA]

NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380

G

biogenesis of lysosomal organelles complex-1, subunit 3

affects expression

triadimefon affects the expression of BLOC1S3 mRNA

NCBI chr 1:79,155,873...79,158,247
Ensembl chr 1:79,155,693...79,158,505

G

BCL2 interacting protein 3 like

decreases expression

triadimefon results in decreased expression of BNIP3L mRNA

NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803

G

bolA family member 1

decreases expression

triadimefon results in decreased expression of BOLA1 mRNA

NCBI chr 2:183,758,515...183,771,445
Ensembl chr 2:183,758,441...183,781,576

G

BPI fold containing family B, member 2

decreases expression

triadimefon results in decreased expression of BPIFB2 mRNA

NCBI chr 3:142,356,990...142,377,053
Ensembl chr 3:142,358,051...142,377,044

G

BTB domain containing 10

increases expression

triadimefon results in increased expression of BTBD10 mRNA

NCBI chr 1:167,431,311...167,489,320
Ensembl chr 1:167,431,329...167,489,916

G

biotinidase

increases expression

triadimefon results in increased expression of BTD mRNA

NCBI chr16:6,863,068...6,894,345
Ensembl chr16:6,862,407...6,940,945

G

BUD31 homolog

increases expression

triadimefon results in increased expression of BUD31 mRNA

NCBI chr12:9,462,838...9,470,387
Ensembl chr12:9,462,441...9,470,509

G

calcium voltage-gated channel auxiliary subunit gamma 2

decreases expression

triadimefon results in decreased expression of CACNG2 mRNA

NCBI chr 7:109,572,838...109,698,516
Ensembl chr 7:109,574,459...109,697,227

G

calpain 7

decreases expression

triadimefon results in decreased expression of CAPN7 mRNA

NCBI chr16:6,545,630...6,581,908
Ensembl chr16:6,545,731...6,581,905

G

caspase 2

decreases expression

triadimefon results in decreased expression of CASP2 mRNA

NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379

G

caspase 3

increases expression

triadimefon results in increased expression of CASP3 mRNA

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 9

decreases expression

triadimefon results in decreased expression of CASP9 mRNA

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

G

catalase

decreases expression

triadimefon results in decreased expression of CAT mRNA; triadimefon results in decreased expression of CAT protein

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

caveolin 1

decreases expression

triadimefon analog results in decreased expression of CAV1 mRNA; triadimefon results in decreased expression of CAV1 mRNA

PMID:26238599 PMID:26705709

NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705

G

caveolin 2

decreases expression

triadimefon results in decreased expression of CAV2 mRNA

NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:45,616,712...45,624,244

G

caveolae associated protein 2

decreases expression

triadimefon results in decreased expression of CAVIN2 mRNA

NCBI chr 9:50,302,079...50,314,096
Ensembl chr 9:50,301,206...50,314,147

G

caveolae associated protein 3

increases expression

triadimefon results in increased expression of PRKCDBP mRNA

NCBI chr 1:159,826,549...159,828,138
Ensembl chr 1:159,826,549...159,828,161

G

Cbl proto-oncogene C

decreases expression

triadimefon results in decreased expression of CBLC mRNA

NCBI chr 1:79,439,975...79,456,755
Ensembl chr 1:79,439,977...79,456,755

G

Cbl proto-oncogene like 1

decreases expression

triadimefon results in decreased expression of CBLL1 mRNA

NCBI chr 6:48,071,190...48,086,174
Ensembl chr 6:48,071,190...48,086,444

G

chromobox 8

affects expression

triadimefon affects the expression of CBX8 mRNA

NCBI chr10:104,294,518...104,296,956
Ensembl chr10:104,294,518...104,297,024

G

coiled-coil domain containing 112

decreases expression

triadimefon results in decreased expression of CCDC112 mRNA

NCBI chr18:38,998,139...39,032,329
Ensembl chr18:38,998,139...39,032,329

G

coiled-coil domain containing 126

decreases expression

triadimefon results in decreased expression of CCDC126 mRNA

NCBI chr 4:78,297,625...78,318,655
Ensembl chr 4:78,297,551...78,318,655

G

coiled-coil domain containing 81

decreases expression

triadimefon results in decreased expression of CCDC81 mRNA

NCBI chr 1:143,739,472...143,791,026
Ensembl chr 1:143,739,474...143,790,926

G

C-C motif chemokine ligand 5

increases expression

triadimefon results in increased expression of CCL5 mRNA; triadimefon results in increased expression of CCL5 protein

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

G

cellular communication network factor 2

decreases expression

triadimefon results in decreased expression of CTGF mRNA

NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734

G

cyclin E2

affects expression

triadimefon affects the expression of CCNE2 mRNA

NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632

G

cyclin G2

affects expression

triadimefon affects the expression of CCNG2 mRNA

NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830

G

CD9 molecule

decreases expression

triadimefon results in decreased expression of CD9 mRNA

PMID:26705709 PMID:30047161

NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222

G

cell division cycle 42

affects expression

triadimefon affects the expression of CDC42 mRNA

NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111

G

CDC42 effector protein 3

increases expression

triadimefon results in increased expression of CDC42EP3 mRNA

NCBI chr 6:15,710,894...15,731,366
Ensembl chr 6:15,708,730...15,732,721

G

cyclin-dependent kinase inhibitor 1A

increases expression

triadimefon results in increased expression of CDKN1A mRNA

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

caudal type homeo box 1

affects expression

triadimefon affects the expression of CDX1 mRNA

NCBI chr18:54,472,587...54,490,913
Ensembl chr18:54,473,444...54,490,814

G

CCAAT/enhancer binding protein gamma

affects expression

triadimefon affects the expression of CEBPG mRNA

NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:87,684,019...87,694,569

G

carboxylesterase 2H

increases expression

triadimefon results in increased expression of CES2 mRNA

PMID:16643972 PMID:16730040 PMID:19409404 PMID:19423681

NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830

G

carboxylesterase 3a

decreases expression

triadimefon results in decreased expression of CES3 mRNA

NCBI chr19:32,992,386...33,000,562

G

checkpoint kinase 2

decreases expression

triadimefon results in decreased expression of CHEK2 mRNA

NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286

G

chitinase 3 like 1

increases expression
decreases expression

triadimefon results in increased expression of CHI3L1 mRNA
triadimefon results in decreased expression of CHI3L1 mRNA

PMID:26705709 PMID:30047161

NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787

G

chondroitin sulfate synthase 1

increases expression

triadimefon results in increased expression of CHSY1 mRNA

NCBI chr 1:119,689,626...119,750,711
Ensembl chr 1:119,686,350...119,750,601

G

chromosome transmission fidelity factor 18

increases expression

triadimefon results in increased expression of CHTF18 mRNA

NCBI chr10:14,743,006...14,751,044
Ensembl chr10:14,742,621...14,751,050

G

cytosolic iron-sulfur assembly component 2A

increases expression

triadimefon results in increased expression of FAM96A mRNA

NCBI chr 8:66,670,533...66,682,455
Ensembl chr 8:66,670,483...66,682,455

G

claudin 1

decreases expression

triadimefon results in decreased expression of CLDN1 mRNA

PMID:19423681 PMID:26705709

NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724

G

C-type lectin domain containing 14A

increases expression

triadimefon results in increased expression of CLEC14A mRNA

NCBI chr 6:75,881,470...75,884,612
Ensembl chr 6:75,881,473...75,884,612

G

CDC-like kinase 1

affects expression

triadimefon affects the expression of CLK1 mRNA

NCBI chr 9:59,947,774...59,959,002
Ensembl chr 9:59,947,764...59,957,000

G

clarin 2

increases expression

triadimefon results in increased expression of CLRN2 mRNA

NCBI chr14:65,656,029...65,666,325
Ensembl chr14:65,656,550...65,666,193

G

cornichon family member 4

increases expression

triadimefon results in increased expression of CNIH4 mRNA

NCBI chr13:92,910,315...92,926,428
Ensembl chr13:92,910,315...92,927,853

G

calponin 1

decreases expression

triadimefon results in decreased expression of CNN1 mRNA

NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098

G

collagen type V alpha 3 chain

increases expression

triadimefon results in increased expression of COL5A3 mRNA

NCBI chr 8:19,304,564...19,349,809
Ensembl chr 8:19,304,571...19,349,853

G

copper metabolism domain containing 1

increases expression

triadimefon results in increased expression of COMMD1 mRNA

NCBI chr14:96,880,463...96,984,494
Ensembl chr14:96,880,463...96,984,501

G

COMM domain containing 8

increases expression

triadimefon results in increased expression of COMMD8 mRNA

NCBI chr14:36,049,040...36,059,617
Ensembl chr14:36,049,004...36,059,617

G

corin, serine peptidase

decreases expression

triadimefon results in decreased expression of CORIN mRNA

NCBI chr14:35,680,601...35,910,703
Ensembl chr14:35,681,304...35,909,503

G

carnitine palmitoyltransferase 1A

affects expression

triadimefon affects the expression of CPT1A mRNA

NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055

G

carnitine palmitoyltransferase 1c

decreases expression

triadimefon results in decreased expression of CPT1C mRNA; triadimefon results in decreased expression of CPT1C protein

NCBI chr 1:95,442,814...95,457,347
Ensembl chr 1:95,442,817...95,457,342

G

cellular retinoic acid binding protein 1

increases expression

triadimefon results in increased expression of CRABP1 protein

NCBI chr 8:55,138,363...55,159,360
Ensembl chr 8:55,151,285...55,159,360

G

cAMP responsive element modulator

decreases expression

triadimefon results in decreased expression of CREM mRNA

NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989

G

cripto, EGF-CFC family member

affects expression

triadimefon affects the expression of CRIPTO mRNA

NCBI chr 8:110,924,774...110,938,545
Ensembl chr 8:110,925,024...110,930,308

G

C-reactive protein

increases expression

triadimefon results in increased expression of CRP mRNA

NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178

G

cryptochrome circadian regulator 1

increases expression

triadimefon results in increased expression of CRY1 mRNA

NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091

G

crystallin, alpha B

decreases expression

triadimefon results in decreased expression of CRYAB mRNA

NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157

G

colony stimulating factor 1

decreases expression

triadimefon analog results in decreased expression of CSF1 mRNA

NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704

G

CTD small phosphatase 2

affects expression

triadimefon affects the expression of CTDSP2 mRNA

NCBI chr 7:62,805,398...62,825,306
Ensembl chr 7:62,805,658...62,825,302

G

CTTNBP2 N-terminal like

increases expression

triadimefon results in increased expression of CTTNBP2NL mRNA

NCBI chr 2:192,507,963...192,554,548
Ensembl chr 2:192,507,963...192,541,101

G

C-X3-C motif chemokine receptor 1

increases expression

triadimefon results in increased expression of CX3CR1 mRNA; triadimefon results in increased expression of CX3CR1 protein

NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014

G

C-X-C motif chemokine ligand 2

decreases expression

triadimefon results in decreased expression of CXCL2 mRNA

NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075

G

cytochrome P450, family 11, subfamily b, polypeptide 2

decreases expression

triadimefon results in decreased expression of CYP11B1 mRNA; triadimefon results in decreased expression of CYP11B1 protein

NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004

G

cytochrome P450, family 11, subfamily b, polypeptide 3

decreases expression

triadimefon results in decreased expression of CYP11B2 mRNA; triadimefon results in decreased expression of CYP11B2 protein

NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048

G

cytochrome P450, family 19, subfamily a, polypeptide 1

decreases activity

triadimefon results in decreased activity of CYP19A1 protein

NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression

triadimefon results in increased expression of CYP1A1 mRNA; triadimefon results in increased expression of CYP1A1 protein

PMID:17178689 PMID:19409404 PMID:20659493 PMID:36179991

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily a, polypeptide 2

increases expression

triadimefon results in increased expression of CYP1A2 mRNA

NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312

G

cytochrome P450, family 1, subfamily b, polypeptide 1

increases expression

triadimefon results in increased expression of CYP1B1 mRNA

NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917

G

cytochrome P450, family 24, subfamily a, polypeptide 1

increases expression

triadimefon results in increased expression of CYP24A1 mRNA

NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383

G

cytochrome P450, family 26, subfamily a, polypeptide 1

increases expression

triadimefon results in increased expression of CYP26A1 mRNA

PMID:19010342 PMID:22664269 PMID:28263823

NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204

G

cytochrome P450, family 27, subfamily b, polypeptide 1

increases expression

triadimefon results in increased expression of CYP27B1 mRNA

NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241

G

cytochrome P450, family 2, subfamily b, polypeptide 1

increases expression

triadimefon results in increased expression of CYP2B1 mRNA; triadimefon results in increased expression of CYP2B1 protein

PMID:17178689 PMID:17484520

NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052

G

cytochrome P450, family 2, subfamily b, polypeptide 2

increases expression

triadimefon results in increased expression of CYP2B2 mRNA; triadimefon results in increased expression of CYP2B2 protein

PMID:17178689 PMID:17484520 PMID:19409404 PMID:19423681

NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566

G

cytochrome P450, family 2, subfamily b, polypeptide 3

affects expression
increases expression
multiple interactions

triadimefon affects the expression of CYP2B3 mRNA
triadimefon results in increased expression of CYP2B10 mRNA
NR1H3 gene mutant form inhibits the reaction [triadimefon results in increased expression of CYP2B10 mRNA]

PMID:17383973 PMID:19010342 PMID:23970803 PMID:25949234

NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, family 2, subfamily c, polypeptide 24

increases expression

triadimefon results in increased expression of CYP2C55 mRNA

PMID:16730040 PMID:23970803

NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238

G

cytochrome P450, family 2, subfamily C, polypeptide 6

decreases expression

triadimefon results in decreased expression of CYP2C29 mRNA

NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596

G

cytochrome P450, family 2, subfamily e, polypeptide 1

decreases expression

triadimefon results in decreased expression of CYP2E1 mRNA

NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023

G

cytochrome P450, family 2, subfamily j, polypeptide 4

increases expression

triadimefon results in increased expression of CYP2J9 mRNA

PMID:16643972 PMID:16730040

NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794

G

cytochrome P450, family 2, subfamily u, polypeptide 1

increases expression

triadimefon results in increased expression of CYP2U1 mRNA

NCBI chr 2:219,849,403...219,866,959
Ensembl chr 2:219,849,407...219,866,882

G

cytochrome P450, family 3, subfamily a, polypeptide 18

increases expression

triadimefon results in increased expression of CYP3A18 mRNA

NCBI chr12:8,880,509...8,930,382
Ensembl chr12:8,880,528...8,930,381

G

cytochrome P450, family 3, subfamily a, polypeptide 2

increases expression
multiple interactions

triadimefon results in increased expression of CYP3A2 mRNA; triadimefon results in increased expression of CYP3A2 protein
[N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with pyrimethanil co-treated with Fenitrothion co-treated with triadimefon co-treated with quinoxyfen co-treated with penconazole] results in increased expression of CYP3A4 mRNA
triadimefon results in increased expression of CYP3A11 mRNA
NR1H3 gene mutant form inhibits the reaction [triadimefon results in increased expression of CYP3A11 mRNA]

PMID:16730040 PMID:17484520 PMID:19010342 PMID:25028461 PMID:25949234

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1

affects expression
increases expression

triadimefon affects the expression of CYP3A23-3A1 mRNA
triadimefon results in increased expression of CYP3A23-3A1 mRNA; triadimefon results in increased expression of CYP3A23-3A1 protein

PMID:16643972 PMID:17383973 PMID:17484520 PMID:19409404

NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030

G

cytochrome P450, family 3, subfamily a, polypeptide 9

increases expression

triadimefon results in increased expression of CYP3A13 mRNA

NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422

G

cytochrome P450, family 51

increases expression
decreases activity

triadimefon results in increased expression of CYP51 mRNA
triadimefon results in decreased activity of CYP51A1 protein

PMID:16989930 PMID:17178688 PMID:17178689 PMID:25949234 PMID:29337257

NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410

G

cytochrome P450 family 8 subfamily B member 1

decreases expression

triadimefon results in decreased expression of CYP8B1 mRNA

NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166

G

dishevelled-binding antagonist of beta-catenin 2

increases expression

triadimefon results in increased expression of DACT2 mRNA

NCBI chr 1:55,181,023...55,191,026
Ensembl chr 1:55,181,024...55,191,096

G

defender against cell death 1

increases expression

triadimefon results in increased expression of DAD1 mRNA

NCBI chr15:27,677,286...27,697,120
Ensembl chr15:27,677,268...27,697,347

G

death associated protein kinase 1

decreases expression

triadimefon results in decreased expression of DAPK1 mRNA

NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991

G

aspartyl-tRNA synthetase 1

affects expression

triadimefon affects the expression of DARS1 mRNA

NCBI chr13:39,857,936...39,913,055
Ensembl chr13:39,857,936...39,913,116

G

D-box binding PAR bZIP transcription factor

decreases expression

triadimefon results in decreased expression of DBP mRNA

NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745

G

DNA-damage-inducible transcript 4

affects expression

triadimefon affects the expression of DDIT4 mRNA

NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105

G

DEAD-box helicase 20

decreases expression

triadimefon results in decreased expression of DDX20 mRNA

NCBI chr 2:193,158,761...193,168,484
Ensembl chr 2:193,158,823...193,166,774

G

DEAD-box helicase 46

decreases expression

triadimefon results in decreased expression of DDX46 mRNA

NCBI chr17:8,942,070...8,988,440
Ensembl chr17:8,944,454...8,988,439

G

diacylglycerol O-acyltransferase 2

decreases expression

triadimefon results in decreased expression of DGAT2 mRNA

NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428

G

7-dehydrocholesterol reductase

increases expression

triadimefon results in increased expression of DHCR7 mRNA

NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055

G

dehydrogenase/reductase 3

increases expression

triadimefon results in increased expression of DHRS3 mRNA

PMID:22664269 PMID:28263823

NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417

G

dehydrogenase/reductase X-linked

decreases expression

triadimefon results in decreased expression of DHRSX mRNA

NCBI chr12:16,299,768...16,304,553
Ensembl chr12:16,299,808...16,304,552

G

iodothyronine deiodinase 3

affects expression

triadimefon affects the expression of DIO3 mRNA

NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660

G

divergent protein kinase domain 1B

decreases expression

triadimefon results in decreased expression of FAM69B mRNA

NCBI chr 3:9,455,914...9,464,169
Ensembl chr 3:9,456,409...9,464,161

G

delta like canonical Notch ligand 1

increases expression

triadimefon results in increased expression of DLL1 mRNA

NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179

G

DnaJ heat shock protein family (Hsp40) member B13

decreases expression

triadimefon results in decreased expression of DNAJB13 mRNA

NCBI chr 1:154,848,586...154,863,042
Ensembl chr 1:154,848,594...154,862,963

G

DnaJ heat shock protein family (Hsp40) member B4

increases expression

triadimefon results in increased expression of DNAJB4 mRNA

NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089

G

DnaJ heat shock protein family (Hsp40) member B9

increases expression

triadimefon results in increased expression of DNAJB9 mRNA

NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063

G

DnaJ heat shock protein family (Hsp40) member C19

increases expression

triadimefon results in increased expression of DNAJC19 mRNA

NCBI chr 2:116,923,272...116,945,312
Ensembl chr 2:116,923,272...116,945,264

G

docking protein 4

increases expression

triadimefon results in increased expression of DOK4 mRNA

NCBI chr19:10,146,520...10,157,187
Ensembl chr19:10,146,474...10,158,203

G

double PHD fingers 2

decreases expression

triadimefon results in decreased expression of DPF2 mRNA

NCBI chr 1:203,183,674...203,199,037
Ensembl chr 1:203,183,686...203,198,983

G

diphthamide biosynthesis 1

increases expression

triadimefon results in increased expression of DPH1 mRNA

NCBI chr10:60,028,081...60,039,764
Ensembl chr10:60,026,048...60,039,850

G

diphthamide biosynthesis 3

increases expression

triadimefon results in increased expression of DPH3 mRNA

NCBI chr16:7,288,295...7,293,734
Ensembl chr16:7,282,705...7,291,265

G

dolichyl-phosphate mannosyltransferase subunit 3, regulatory

increases expression

triadimefon results in increased expression of DPM3 mRNA

NCBI chr 2:174,676,532...174,677,047
Ensembl chr 2:174,676,363...174,677,668
Ensembl chr15:174,676,363...174,677,668

G

desmoplakin

decreases expression

triadimefon results in decreased expression of DSP mRNA

NCBI chr17:26,623,602...26,671,692
Ensembl chr17:26,623,588...26,671,800

G

dual serine/threonine and tyrosine protein kinase

decreases expression

triadimefon results in decreased expression of DSTYK mRNA

NCBI chr13:43,857,266...43,905,280
Ensembl chr13:43,857,266...43,905,269

G

deltex E3 ubiquitin ligase 2

increases expression

triadimefon results in increased expression of DTX2 mRNA

NCBI chr12:20,643,289...20,682,908
Ensembl chr12:20,643,297...20,682,885

G

dual specificity phosphatase 5

increases expression

triadimefon results in increased expression of DUSP5 mRNA

NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818

G

dual specificity phosphatase 6

increases expression

triadimefon results in increased expression of DUSP6 mRNA

NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185

G

dishevelled segment polarity protein 1

decreases expression

triadimefon results in decreased expression of DVL1 mRNA

NCBI chr 5:166,456,989...166,468,733
Ensembl chr 5:166,456,686...166,468,664

G

ethylmalonyl-CoA decarboxylase 1

increases expression

triadimefon results in increased expression of ECHDC1 mRNA

NCBI chr 1:28,476,354...28,507,173
Ensembl chr 1:28,476,200...28,507,319

G

endothelial cell surface expressed chemotaxis and apoptosis regulator

decreases expression

triadimefon results in decreased expression of ECSCR mRNA

NCBI chr18:27,309,711...27,319,106
Ensembl chr18:27,309,718...27,319,032

G

endothelin 1

decreases expression

triadimefon results in decreased expression of EDN1 mRNA

NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885

G

eukaryotic translation elongation factor 1 alpha 1

decreases expression

triadimefon results in decreased expression of EEF1A1 mRNA

NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839

G

eukaryotic elongation factor-2 kinase

decreases expression

triadimefon results in decreased expression of EEF2K mRNA

NCBI chr 1:175,393,119...175,456,756
Ensembl chr 1:175,393,154...175,455,164

G

epidermal growth factor

decreases expression

triadimefon results in decreased expression of EGF mRNA

NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064

G

EGF-like, fibronectin type III and laminin G domains

increases expression

triadimefon results in increased expression of EGFLAM mRNA

NCBI chr 2:56,301,945...56,476,665
Ensembl chr 2:56,302,566...56,476,298

G

early growth response 1

increases expression

triadimefon results in increased expression of EGR1 mRNA

NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766

G

early growth response 2

decreases expression

triadimefon results in decreased expression of EGR2 mRNA

NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562

G

early growth response 3

increases expression

triadimefon results in increased expression of EGR3 mRNA

NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627

G

eukaryotic translation initiation factor 1

affects expression

triadimefon affects the expression of EIF1 mRNA

NCBI chr10:85,246,751...85,248,842
Ensembl chr10:85,246,764...85,427,327

G

eukaryotic translation initiation factor 4A2

increases expression

triadimefon results in increased expression of EIF4A2 mRNA

NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781

G

eukaryotic translation initiation factor 4E

increases expression

triadimefon results in increased expression of EIF4E mRNA

NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683

G

endosome-lysosome associated apoptosis and autophagy regulator 1

decreases expression

triadimefon results in decreased expression of ELAPOR1 mRNA

NCBI chr 2:196,089,199...196,169,055
Ensembl chr 2:196,091,646...196,168,716

G

elongation factor for RNA polymerase II 2

decreases expression

triadimefon results in decreased expression of ELL2 mRNA

NCBI chr 2:5,189,375...5,258,781
Ensembl chr 2:5,189,971...5,258,781

G

elongin B

increases expression

triadimefon results in increased expression of TCEB2 mRNA

NCBI chr10:12,848,830...12,853,897
Ensembl chr10:12,848,827...12,853,635

G

essential meiotic structure-specific endonuclease subunit 2

increases expression

triadimefon results in increased expression of EME2 mRNA

NCBI chr10:13,913,216...13,915,991
Ensembl chr10:13,913,221...13,915,968

G

EMAP like 5

decreases expression

triadimefon results in decreased expression of EML5 mRNA

NCBI chr 6:118,046,655...118,175,831
Ensembl chr 6:118,046,655...118,175,831

G

energy homeostasis associated

decreases expression

triadimefon results in decreased expression of ENHO mRNA

NCBI chr 5:56,800,980...56,802,777
Ensembl chr 5:56,800,980...56,802,777

G

Eph receptor A2

decreases activity

triadimefon results in decreased activity of EPHA2 protein

NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117

G

EPM2A interacting protein 1

decreases expression

triadimefon results in decreased expression of EPM2AIP1 mRNA

NCBI chr 8:111,233,871...111,241,219
Ensembl chr 8:111,233,826...111,241,871

G

epididymal peptidase inhibitor

decreases expression

triadimefon results in decreased expression of EPPIN mRNA

NCBI chr 3:153,312,396...153,319,310
Ensembl chr 3:153,312,396...153,319,310

G

epiregulin

increases expression

triadimefon results in increased expression of EREG mRNA

NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062

G

ETS transcription factor ERG

decreases expression

triadimefon results in decreased expression of ERG mRNA

NCBI chr11:34,678,614...34,900,951
Ensembl chr11:34,678,618...34,845,871

G

endothelial cell adhesion molecule

increases expression

triadimefon results in increased expression of ESAM mRNA

NCBI chr 8:37,238,228...37,249,217
Ensembl chr 8:37,238,287...37,249,215

G

estrogen receptor 1

multiple interactions
increases expression

triadimefon binds to and results in increased activity of ESR1 protein
triadimefon results in increased expression of ESR1 mRNA

PMID:10789375 PMID:19363144

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

exostosin-like glycosyltransferase 1

decreases expression

triadimefon results in decreased expression of EXTL1 mRNA

NCBI chr 5:146,573,911...146,589,115
Ensembl chr 5:146,573,912...146,589,115

G

F2R like thrombin or trypsin receptor 3

decreases expression

triadimefon results in decreased expression of F2RL3 mRNA

NCBI chr16:17,117,441...17,119,434
Ensembl chr16:17,117,441...17,119,472

G

fatty acid 2-hydroxylase

decreases expression

triadimefon results in decreased expression of FA2H mRNA

NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153

G

fatty acid binding protein 4

decreases expression

triadimefon results in decreased expression of FABP4 mRNA

NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578

G

fumarylacetoacetate hydrolase

decreases expression

triadimefon results in decreased expression of FAH mRNA

NCBI chr 1:138,548,830...138,571,599
Ensembl chr 1:138,548,834...138,571,505

G

family with sequence similarity 13, member B

decreases expression

triadimefon results in decreased expression of FAM13B mRNA

NCBI chr18:26,040,285...26,107,112
Ensembl chr18:26,040,285...26,106,587

G

fibrillin 1

decreases expression

triadimefon results in decreased expression of FBN1 mRNA

NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889

G

F-box protein 27

decreases expression

triadimefon results in decreased expression of FBXO27 mRNA

NCBI chr 1:83,965,426...83,987,781
Ensembl chr 1:83,965,986...83,987,778

G

F-box protein 42

increases expression

triadimefon results in increased expression of FBXO42 mRNA

NCBI chr 5:153,451,162...153,509,564
Ensembl chr 5:153,451,153...153,506,342

G

farnesyl diphosphate farnesyl transferase 1

increases expression
affects expression

triadimefon results in increased expression of FDFT1 mRNA
triadimefon affects the expression of FDFT1 mRNA

PMID:17178688 PMID:21195148

NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287

G

flap structure-specific endonuclease 1

increases expression

triadimefon results in increased expression of FEN1 mRNA

NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003

G

fibrinogen-like 1

increases expression

triadimefon results in increased expression of FGL1 mRNA

NCBI chr16:51,120,652...51,150,907
Ensembl chr16:51,120,694...51,151,093

G

FKBP prolyl isomerase 1A

increases expression

triadimefon results in increased expression of FKBP1A mRNA

NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743

G

Fms related receptor tyrosine kinase 4

decreases expression

triadimefon results in decreased expression of FLT4 mRNA

NCBI chr10:33,913,725...33,954,770
Ensembl chr10:33,913,608...33,954,770

G

formin binding protein 1-like

decreases expression

triadimefon results in decreased expression of FNBP1L mRNA

NCBI chr 2:210,647,241...210,748,203
Ensembl chr 2:210,647,246...210,738,455

G

forkhead box B1

affects expression
decreases expression

triadimefon affects the expression of FOXB1 mRNA
triadimefon results in decreased expression of FOXB1 mRNA

PMID:21195148 PMID:30047161

NCBI chr 8:70,407,221...70,409,841
Ensembl chr 8:70,408,186...70,409,781

G

forkhead box C1

decreases expression

triadimefon results in decreased expression of FOXC1 mRNA

NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803

G

forkhead box P1

decreases expression

triadimefon results in decreased expression of FOXP1 mRNA

NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258

G

follistatin

increases expression

triadimefon results in increased expression of FST mRNA

NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571

G

GABA type A receptor-associated protein

decreases expression

triadimefon results in decreased expression of GABARAP mRNA

NCBI chr10:54,714,777...54,718,099
Ensembl chr10:54,714,198...54,717,765

G

gamma-aminobutyric acid type B receptor subunit 1

decreases expression

triadimefon results in decreased expression of GABBR1 mRNA

NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994

G

gamma-aminobutyric acid type A receptor subunit alpha 2

decreases expression

triadimefon results in decreased expression of GABRA2 mRNA

NCBI chr14:37,097,251...37,230,030
Ensembl chr14:37,097,279...37,228,944

G

gamma-aminobutyric acid type A receptor subunit gamma 3

increases expression

triadimefon results in increased expression of GABRG3 mRNA

NCBI chr 1:107,627,450...108,247,483
Ensembl chr 1:107,627,390...108,246,763

G

gamma-aminobutyric acid type A receptor subunit rho 1

increases expression

triadimefon results in increased expression of GABRR1 mRNA

NCBI chr 5:47,524,151...47,561,228
Ensembl chr 5:47,524,151...47,561,228

G

growth arrest and DNA-damage-inducible, beta

increases expression

triadimefon results in increased expression of GADD45B mRNA

NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046

G

glycyl-tRNA synthetase 1

increases expression

triadimefon results in increased expression of GARS1 mRNA

NCBI chr 4:84,171,596...84,212,609
Ensembl chr 4:84,171,596...84,212,609

G

growth arrest-specific 2

decreases expression

triadimefon results in decreased expression of GAS2 mRNA

NCBI chr 1:101,452,361...101,582,619
Ensembl chr 1:101,482,591...101,582,619

G

1,4-alpha-glucan branching enzyme 1

decreases expression

triadimefon results in decreased expression of GBE1 mRNA

NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210

G

guanylate binding protein 1

decreases expression

triadimefon results in decreased expression of GBP1 mRNA

NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131
Ensembl chr 2:231,398,163...231,432,131

G

gastrulation brain homeobox 2

affects expression
increases expression

triadimefon affects the expression of GBX2 mRNA
triadimefon results in increased expression of GBX2 mRNA

PMID:21195148 PMID:28263823

NCBI chr 9:90,509,633...90,512,212
Ensembl chr 9:90,509,633...90,512,212

G

gem (nuclear organelle) associated protein 2

decreases expression

triadimefon results in decreased expression of GEMIN2 mRNA

NCBI chr 6:76,706,424...76,721,154
Ensembl chr 6:76,707,523...76,721,153

G

GDNF family receptor alpha 1

decreases expression

triadimefon results in decreased expression of GFRA1 mRNA

NCBI chr 1:257,315,682...257,552,004
Ensembl chr 1:257,321,742...257,551,473

G

GLI family zinc finger 4

decreases expression

triadimefon results in decreased expression of GLI4 mRNA

NCBI chr 7:107,325,584...107,330,911
Ensembl chr 7:107,325,607...107,330,907

G

GLI pathogenesis-related 1

decreases expression

triadimefon results in decreased expression of GLIPR1 mRNA

NCBI chr 7:47,487,342...47,498,974
Ensembl chr 7:47,487,345...47,498,429

G

glia maturation factor, gamma

increases expression

triadimefon results in increased expression of GMFG mRNA

NCBI chr 1:83,728,797...83,739,189
Ensembl chr 1:83,728,776...83,739,183

G

G protein subunit alpha 14

decreases expression

triadimefon results in decreased expression of GNA14 mRNA

NCBI chr 1:213,714,993...213,900,083
Ensembl chr 1:213,716,020...213,897,423

G

G protein-coupled receptor 62

decreases expression

triadimefon results in decreased expression of GPR62 mRNA

NCBI chr 8:107,103,225...107,105,311
Ensembl chr 8:107,103,980...107,105,056

G

G protein-coupled receptor 68

decreases expression

triadimefon results in decreased expression of GPR68 mRNA

NCBI chr 6:120,135,620...120,166,089
Ensembl chr 6:120,135,436...120,166,089

G

glutathione peroxidase 1

decreases expression

triadimefon results in decreased expression of GPX1 mRNA; triadimefon results in decreased expression of GPX1 protein

NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024

G

GRAM domain containing 1B

increases expression

triadimefon results in increased expression of GRAMD1B mRNA

NCBI chr 8:40,654,492...40,893,869
Ensembl chr 8:40,659,182...40,893,925

G

GRAM domain containing 1C

decreases expression

triadimefon results in decreased expression of GRAMD1C mRNA

NCBI chr11:56,633,229...56,718,570
Ensembl chr11:56,633,227...56,718,570

G

GRAM domain containing 2A

decreases expression

triadimefon results in decreased expression of GRAMD2 mRNA

NCBI chr 8:60,079,744...60,117,788
Ensembl chr 8:60,080,338...60,115,842

G

goosecoid homeobox

decreases expression

triadimefon results in decreased expression of GSC mRNA

NCBI chr 6:123,388,072...123,390,111
Ensembl chr 6:123,388,072...123,390,111

G

glutathione-disulfide reductase

affects expression

triadimefon affects the expression of GSR mRNA

NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661

G

glutathione S-transferase alpha 1

affects expression

triadimefon affects the expression of GSTA1 mRNA

NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121

G

glutathione S-transferase alpha 2

increases expression

triadimefon results in increased expression of GSTA2 mRNA

NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798

G

glutathione S-transferase alpha 5

increases expression

triadimefon results in increased expression of GSTA5 mRNA

NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472

G

glutathione S-transferase mu 1

affects expression

triadimefon affects the expression of GSTM1 mRNA

NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411

G

glutathione S-transferase mu 4

increases expression

triadimefon results in increased expression of GSTM4 mRNA

NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323

G

glutathione S-transferase, mu 5

increases expression
multiple interactions

triadimefon results in increased expression of GSTM3 mRNA
NR1H3 gene mutant form promotes the reaction [triadimefon results in increased expression of GSTM3 mRNA]

PMID:16643972 PMID:23970803 PMID:25949234

NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553

G

glutathione S-transferase theta 1

increases expression

triadimefon results in increased expression of GSTT1 mRNA

NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585

G

guanylate cyclase activator 1A

decreases expression

triadimefon results in decreased expression of GUCA1A mRNA

NCBI chr 9:13,588,988...13,598,566
Ensembl chr 9:13,588,525...13,598,565

G

H1.0 linker histone

decreases expression

triadimefon results in decreased expression of H1F0 mRNA

NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694

G

H2A.X variant histone

increases expression

triadimefon results in increased expression of H2AX mRNA

NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239

G

hydroxyacid oxidase 2

decreases expression

triadimefon results in decreased expression of HAO2 mRNA

NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425

G

hyaluronan and proteoglycan link protein 1

decreases expression

triadimefon results in decreased expression of HAPLN1 mRNA

NCBI chr 2:20,631,640...20,696,388
Ensembl chr 2:20,631,640...20,693,777

G

histone acetyltransferase 1

increases expression

triadimefon results in increased expression of HAT1 mRNA

NCBI chr 3:56,217,344...56,265,021
Ensembl chr 3:56,217,342...56,275,517

G

hyperpolarization-activated cyclic nucleotide-gated potassium channel 1

decreases expression

triadimefon results in decreased expression of HCN1 mRNA

NCBI chr 2:49,495,771...49,899,983
Ensembl chr 2:49,495,771...49,899,774

G

HDGF like 3

increases expression

triadimefon results in increased expression of HDGFRP3 mRNA

NCBI chr 1:135,822,600...135,876,719
Ensembl chr 1:135,827,549...135,876,719

G

hes family bHLH transcription factor 1

affects expression

triadimefon affects the expression of HES1 mRNA

NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192

G

homeostatic iron regulator

increases expression

triadimefon results in increased expression of HFE mRNA

NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502

G

HGF activator

decreases expression

triadimefon results in decreased expression of HGFAC mRNA

NCBI chr14:75,707,588...75,714,182
Ensembl chr14:75,707,591...75,714,278

G

histone cluster 1 H2B family member D

increases expression

triadimefon results in increased expression of HIST1H2BD mRNA

NCBI chr17:42,792,887...42,793,268

G

histone cluster 1, H4m

increases expression

triadimefon results in increased expression of HIST1H4M mRNA

NCBI chr17:42,698,016...42,698,420
Ensembl chr17:42,698,025...42,698,958

G

3-hydroxy-3-methylglutaryl-CoA reductase

increases expression

triadimefon results in increased expression of HMGCR mRNA

PMID:17178689 PMID:19363144 PMID:19423681

NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703

G

3-hydroxy-3-methylglutaryl-CoA synthase 1

increases expression

triadimefon results in increased expression of HMGCS1 mRNA

PMID:17178688 PMID:17178689

NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100

G

homeobox A1

affects expression

triadimefon affects the expression of HOXA1 mRNA

NCBI chr 4:81,255,814...81,258,587
Ensembl chr 4:81,255,883...81,258,504

G

HPS6, biogenesis of lysosomal organelles complex 2 subunit 3

affects expression

triadimefon affects the expression of HPS6 mRNA

NCBI chr 1:244,853,256...244,855,865
Ensembl chr 1:244,853,194...244,855,883

G

hydroxysteroid 11-beta dehydrogenase 1

increases reduction

HSD11B1 protein results in increased reduction of triadimefon

NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687

G

hydroxysteroid (17-beta) dehydrogenase 2

decreases expression

triadimefon results in decreased expression of HSD17B2 mRNA

NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

decreases expression

triadimefon results in decreased expression of HSD3B2 mRNA

NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999

G

heat shock protein 90 beta family member 1

increases expression

triadimefon results in increased expression of HSP90B1 mRNA

NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788

G

heat shock protein family A (Hsp70) member 13

increases expression

triadimefon results in increased expression of HSPA13 mRNA

NCBI chr11:14,375,669...14,389,853
Ensembl chr11:14,373,275...14,389,895

G

heat shock protein family A (Hsp70) member 4 like

decreases expression

triadimefon results in decreased expression of HSPA4L mRNA

NCBI chr 2:123,740,384...123,793,088
Ensembl chr 2:123,740,384...123,793,084

G

heat shock protein family A (Hsp70) member 5

decreases expression

triadimefon results in decreased expression of HSPA5 mRNA

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

heat shock protein family A (Hsp70) member 8

increases expression

triadimefon results in increased expression of HSPA8 mRNA

NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259

G

HIV-1 Tat interactive protein 2

increases expression

triadimefon results in increased expression of HTATIP2 mRNA

NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629

G

inhibitor of DNA binding 2

affects expression

triadimefon affects the expression of ID2 mRNA

NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400

G

isopentenyl-diphosphate delta isomerase 1

increases expression

triadimefon results in increased expression of IDI1 mRNA

PMID:17178688 PMID:17178689

NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357

G

immediate early response 3

affects expression

triadimefon affects the expression of IER3 mRNA

NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583

G

intermediate filament family orphan 1

decreases expression

triadimefon results in decreased expression of IFFO1 mRNA

NCBI chr 4:157,945,075...157,962,302
Ensembl chr 4:157,945,107...157,962,302

G

interferon induced transmembrane protein 2

increases expression

triadimefon results in increased expression of IFITM2 mRNA

NCBI chr 1:196,051,539...196,052,719
Ensembl chr 1:196,051,537...196,052,741

G

intraflagellar transport 43

increases expression

triadimefon results in increased expression of IFT43 mRNA

NCBI chr 6:105,729,734...105,806,257
Ensembl chr 6:105,729,792...105,806,257

G

insulin-like growth factor 1

decreases expression

triadimefon results in decreased expression of IGF1 mRNA; triadimefon results in decreased expression of IGF1 protein

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

G

inhibitor of nuclear factor kappa B kinase subunit epsilon

increases expression

triadimefon results in increased expression of IKBKE mRNA

NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143

G

interleukin 17 receptor D

affects expression

triadimefon affects the expression of IL17RD mRNA

NCBI chr16:2,228,438...2,295,122
Ensembl chr16:2,228,287...2,292,556

G

interleukin 1 receptor type 1

increases expression

triadimefon results in increased expression of IL1R1 mRNA

NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937

G

interleukin 5

decreases expression

triadimefon results in decreased expression of IL5 mRNA

NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213

G

interleukin 7 receptor

decreases expression

triadimefon results in decreased expression of IL7R mRNA

NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757

G

inosine monophosphate dehydrogenase 2

affects expression

triadimefon affects the expression of IMPDH2 mRNA

NCBI chr 8:109,256,705...109,261,365
Ensembl chr 8:109,256,728...109,261,359

G

indolethylamine N-methyltransferase

decreases expression

triadimefon results in decreased expression of INMT mRNA

NCBI chr 4:84,318,197...84,322,493
Ensembl chr 4:84,318,197...84,322,493

G

inositol polyphosphate-4-phosphatase type I A

increases expression

triadimefon results in increased expression of INPP4A mRNA

NCBI chr 9:39,528,245...39,650,574
Ensembl chr 9:39,528,674...39,646,581

G

insulin induced gene 1

affects expression

triadimefon affects the expression of INSIG1 mRNA

NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952

G

INSM transcriptional repressor 2

decreases expression

triadimefon results in decreased expression of INSM2 mRNA

NCBI chr 6:72,973,861...72,976,453

G

importin 11

increases expression

triadimefon results in increased expression of IPO11 mRNA

NCBI chr 2:38,169,688...38,342,929

G

interferon regulatory factor 6

increases expression

triadimefon results in increased expression of IRF6 mRNA

NCBI chr13:104,672,179...104,691,386
Ensembl chr13:104,672,179...104,691,386

G

immunity-related GTPase M

affects expression

triadimefon affects the expression of IRGM1 mRNA

NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578

G

integrin subunit alpha 4

decreases expression

triadimefon analog results in decreased expression of ITGA4 mRNA

NCBI chr 3:64,162,764...64,235,010
Ensembl chr 3:64,163,085...64,233,715

G

integrin subunit beta 3

decreases expression

triadimefon analog results in decreased expression of ITGB3 mRNA

NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679

G

integrin subunit beta like 1

decreases expression

triadimefon results in decreased expression of ITGBL1 mRNA

NCBI chr15:100,780,184...101,041,734
Ensembl chr15:100,780,184...101,041,733

G

inter-alpha trypsin inhibitor, heavy chain 3

decreases expression

triadimefon results in decreased expression of ITIH3 mRNA

NCBI chr16:6,101,922...6,117,154
Ensembl chr16:6,101,930...6,116,924

G

janus kinase and microtubule interacting protein 1

affects expression

triadimefon affects the expression of JAKMIP1 mRNA

NCBI chr14:73,646,299...73,766,830
Ensembl chr14:73,632,428...73,713,993

G

jumonji domain containing 6, arginine demethylase and lysine hydroxylase

affects expression

triadimefon affects the expression of JMJD6 mRNA

NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182

G

jumonji domain containing 7

increases expression

triadimefon results in increased expression of JMJD7 mRNA

NCBI chr 3:106,998,454...107,004,538
Ensembl chr 3:106,998,477...107,004,538

G

JunD proto-oncogene, AP-1 transcription factor subunit

increases expression

triadimefon results in increased expression of JUND mRNA

NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799

G

kalirin, RhoGEF kinase

decreases expression

triadimefon results in decreased expression of KALRN mRNA

NCBI chr11:66,198,155...66,803,166
Ensembl chr11:66,198,173...66,797,610

G

lysine acetyltransferase 2B

decreases expression

triadimefon results in decreased expression of KAT2B mRNA

NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064

G

potassium voltage-gated channel subfamily H member 1

decreases expression

triadimefon results in decreased expression of KCNH1 mRNA

NCBI chr13:103,722,140...104,024,762
Ensembl chr13:103,722,245...104,024,740

G

lysine demethylase 8

increases expression

triadimefon results in increased expression of KDM8 mRNA

NCBI chr 1:180,013,969...180,028,829
Ensembl chr 1:180,020,656...180,028,841

G

KLF transcription factor 2

decreases expression

triadimefon results in decreased expression of KLF2 mRNA

NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944

G

killer cell lectin like receptor G1

increases expression

triadimefon results in increased expression of KLRG1 mRNA

NCBI chr 4:155,455,465...155,467,301
Ensembl chr 4:155,455,495...155,467,424

G

karyopherin subunit alpha 2

increases expression

triadimefon results in increased expression of KPNA2 mRNA

NCBI chr10:91,933,951...91,946,115
Ensembl chr10:91,933,951...91,946,150

G

karyopherin subunit beta 1

increases expression

triadimefon results in increased expression of KPNB1 mRNA

NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605

G

keratin 14

decreases expression

triadimefon results in decreased expression of KRT14 mRNA

NCBI chr10:85,137,786...85,142,054
Ensembl chr10:85,066,802...85,171,799

G

keratin 18

decreases expression

triadimefon results in decreased expression of KRT18 mRNA

NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166

G

keratin 19

decreases expression

triadimefon results in decreased expression of KRT19 mRNA

NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799

G

low density lipoprotein receptor

affects expression
decreases expression

triadimefon affects the expression of LDLR mRNA
triadimefon results in decreased expression of LDLR mRNA

PMID:21195148 PMID:36179991

NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580

G

LIF receptor subunit alpha

decreases expression

triadimefon results in decreased expression of LIFR mRNA

NCBI chr 2:56,224,393...56,292,988
Ensembl chr 2:56,250,120...56,286,699

G

LIM and cysteine-rich domains 1

decreases expression

triadimefon results in decreased expression of LMCD1 mRNA

NCBI chr 4:145,393,153...145,452,049
Ensembl chr 4:145,393,145...145,452,046

G

LIM domain only 4

increases expression

triadimefon results in increased expression of LMO4 mRNA

NCBI chr 2:233,264,180...233,280,881
Ensembl chr 2:233,264,182...233,280,880

G

lipoprotein lipase

increases expression

triadimefon results in increased expression of LPL mRNA

NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249

G

LDL receptor related protein 8

affects expression

triadimefon affects the expression of LRP8 mRNA

NCBI chr 5:122,563,468...122,635,434
Ensembl chr 5:122,563,453...122,631,352

G

leucine rich repeat containing 32

decreases expression

triadimefon results in decreased expression of LRRC32 mRNA

NCBI chr 1:152,785,709...152,802,997
Ensembl chr 1:152,786,511...152,798,373

G

leucine rich repeat containing 45

decreases expression

triadimefon results in decreased expression of LRRC45 mRNA

NCBI chr10:105,994,468...106,002,425
Ensembl chr10:105,993,087...106,002,424

G

leucine rich repeat containing 75A

increases expression

triadimefon results in increased expression of LRRC75A mRNA

PMID:22664269 PMID:28263823

NCBI chr10:47,298,222...47,343,301
Ensembl chr10:47,297,288...47,343,664

G

LSM11, U7 small nuclear RNA associated

affects expression

triadimefon affects the expression of LSM11 mRNA

NCBI chr10:30,367,841...30,385,956
Ensembl chr10:30,370,727...30,385,944

G

LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated

increases expression

triadimefon results in increased expression of LSM3 mRNA

NCBI chr 4:124,021,023...124,027,269
Ensembl chr 4:124,021,023...124,027,269

G

lanosterol synthase

affects expression

triadimefon affects the expression of LSS mRNA

NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762

G

LUC7-like

affects expression

triadimefon affects the expression of LUC7L mRNA

NCBI chr10:15,273,340...15,307,131
Ensembl chr10:15,273,348...15,303,112

G

latexin

increases expression

triadimefon results in increased expression of LXN mRNA

NCBI chr 2:151,727,556...151,733,426
Ensembl chr 2:151,727,102...151,733,460

G

mitotic arrest deficient 1 like 1

increases expression

triadimefon results in increased expression of MAD1L1 mRNA

NCBI chr12:14,320,892...14,630,750
Ensembl chr12:14,320,892...14,630,703

G

MAF1 homolog, negative regulator of RNA polymerase III

decreases expression

triadimefon results in decreased expression of MAF1 mRNA

NCBI chr 7:108,075,173...108,078,252
Ensembl chr 7:108,075,189...108,078,249

G

MAF bZIP transcription factor B

decreases expression

triadimefon results in decreased expression of MAFB mRNA

NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031

G

mago homolog, exon junction complex subunit

increases expression

triadimefon results in increased expression of MAGOH mRNA

NCBI chr 5:122,639,268...122,646,650
Ensembl chr 5:122,639,308...122,646,617

G

MAM domain containing 2

decreases expression

triadimefon results in decreased expression of MAMDC2 mRNA

NCBI chr 1:220,863,959...221,016,493
Ensembl chr 1:220,863,976...221,016,354

G

mitogen activated protein kinase 1

decreases phosphorylation

triadimefon results in decreased phosphorylation of MAPK1 protein

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

decreases phosphorylation

triadimefon results in decreased phosphorylation of MAPK3 protein

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

myristoylated alanine rich protein kinase C substrate

increases expression

triadimefon results in increased expression of MARCKS mRNA

NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012

G

melanocortin 2 receptor

decreases expression

triadimefon results in decreased expression of MC2R mRNA; triadimefon results in decreased expression of MC2R protein

NCBI chr18:62,001,980...62,015,567
Ensembl chr18:62,004,948...62,015,488

G

melanoma cell adhesion molecule

decreases expression

triadimefon results in decreased expression of MCAM mRNA

NCBI chr 8:44,479,391...44,487,575
Ensembl chr 8:44,479,376...44,487,571

G

mediator complex subunit 31

decreases expression

triadimefon results in decreased expression of MED31 mRNA

NCBI chr10:56,836,944...56,840,326
Ensembl chr10:56,836,944...56,840,326

G

meiosis/spermiogenesis associated 1

increases expression

triadimefon results in increased expression of MEIG1 mRNA

NCBI chr17:74,810,791...74,828,433
Ensembl chr17:74,814,632...74,828,433

G

mesoderm posterior bHLH transcription factor 2

affects expression

triadimefon affects the expression of MESP2 mRNA

NCBI chr 1:133,756,601...133,759,207
Ensembl chr 1:133,756,601...133,759,198

G

methyltransferase 16, RNA N6-adenosine

affects expression

triadimefon affects the expression of METTL16 mRNA

NCBI chr10:59,640,915...59,697,291
Ensembl chr10:59,640,972...59,687,061

G

microfibril associated protein 5

decreases expression

triadimefon results in decreased expression of MFAP5 mRNA

NCBI chr 4:155,727,925...155,750,458
Ensembl chr 4:155,727,925...155,750,458

G

monoglyceride lipase

decreases expression

triadimefon results in decreased expression of MGLL mRNA

NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179

G

microtubule associated monooxygenase, calponin and LIM domain containing 2

decreases expression

triadimefon results in decreased expression of MICAL2 mRNA

NCBI chr 1:166,345,853...166,530,575
Ensembl chr 1:166,345,859...166,471,719
Ensembl chr 1:166,345,859...166,471,719

G

MHC class I polypeptide-related sequence B

decreases expression

triadimefon results in decreased expression of MICB mRNA

NCBI chr 1:78,495,779...78,513,030
Ensembl chr 1:78,495,779...78,512,827

G

mirror-image polydactyly 1

decreases expression

triadimefon results in decreased expression of MIPOL1 mRNA

NCBI chr 6:74,755,293...75,090,403
Ensembl chr 6:74,755,395...75,086,811

G

microRNA 135b

decreases expression

triadimefon results in decreased expression of MIR135B mRNA

NCBI chr13:43,638,857...43,638,953
Ensembl chr13:43,638,857...43,638,953

G

microRNA 205

decreases expression

triadimefon results in decreased expression of MIR205 mRNA

NCBI chr13:105,035,878...105,035,985
Ensembl chr13:105,035,878...105,035,985

G

microRNA 20b

decreases expression

triadimefon results in decreased expression of MIR20B mRNA

NCBI chr X:132,422,211...132,422,282
Ensembl chr X:132,422,211...132,422,282

G

microRNA 211

decreases expression

triadimefon results in decreased expression of MIR211 mRNA

NCBI chr 1:117,777,539...117,777,644
Ensembl chr 1:117,777,539...117,777,644

G

microRNA 363

decreases expression

triadimefon results in decreased expression of MIR363 mRNA

PMID:20175128 PMID:23159985

NCBI chr X:132,421,791...132,421,877
Ensembl chr X:132,421,791...132,421,877

G

microRNA 509

decreases expression

triadimefon results in decreased expression of MIR509 mRNA

NCBI chr X:146,688,132...146,688,216
Ensembl chr X:146,688,132...146,688,216

G

microRNA 761

decreases expression

triadimefon results in decreased expression of MIR761 mRNA

NCBI chr 5:123,776,534...123,776,609
Ensembl chr 5:123,776,534...123,776,609

G

microRNA 875

decreases expression

triadimefon results in decreased expression of MIR875 mRNA

NCBI chr 7:66,861,955...66,862,027
Ensembl chr 7:66,861,955...66,862,027

G

matrix metallopeptidase 19

decreases expression

triadimefon results in decreased expression of MMP19 mRNA

NCBI chr 7:1,221,229...1,229,555
Ensembl chr 7:1,221,343...1,229,555

G

matrix metallopeptidase 9

decreases expression

triadimefon analog results in decreased expression of MMP9 mRNA

NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120

G

motor neuron and pancreas homeobox 1

decreases expression

triadimefon results in decreased expression of MNX1 mRNA

NCBI chr 4:5,866,506...5,871,465
Ensembl chr 4:5,866,506...5,871,465

G

mitochondrial rRNA methyltransferase 1

affects expression

triadimefon affects the expression of MRM1 mRNA

NCBI chr10:69,690,406...69,697,326
Ensembl chr10:69,690,421...69,696,709

G

mitochondrial ribosomal protein L23

increases expression

triadimefon results in increased expression of MRPL23 mRNA

NCBI chr 1:197,687,452...197,695,222
Ensembl chr 1:197,687,347...197,695,222

G

mitochondrial ribosomal protein L27

increases expression

triadimefon results in increased expression of MRPL27 mRNA

NCBI chr10:79,595,459...79,601,242
Ensembl chr10:79,595,479...79,601,239

G

mitochondrial ribosomal protein S18B

decreases expression

triadimefon results in decreased expression of MRPS18B mRNA

NCBI chr20:2,838,174...2,844,260
Ensembl chr20:2,838,030...2,844,260

G

musashi RNA-binding protein 2

decreases expression

triadimefon results in decreased expression of MSI2 mRNA

NCBI chr10:73,143,760...73,510,566
Ensembl chr10:73,147,380...73,510,157

G

methylsterol monooxygenase 1

affects expression

triadimefon affects the expression of MSMO1 mRNA

NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016

G

msh homeobox 2

decreases expression

triadimefon results in decreased expression of MSX2 mRNA

NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879

G

metallothionein 1

increases expression

triadimefon results in increased expression of MT1 mRNA

NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049

G

metallothionein 2A

increases expression

triadimefon results in increased expression of MT2 mRNA

NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784

G

methylenetetrahydrofolate reductase

decreases expression

triadimefon results in decreased expression of MTHFR mRNA

NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797

G

mevalonate diphosphate decarboxylase

increases expression

triadimefon results in increased expression of MVD mRNA

PMID:17178688 PMID:17178689

NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971

G

mevalonate kinase

increases expression

triadimefon results in increased expression of MVK mRNA

NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882

G

myc target 1

increases expression

triadimefon results in increased expression of MYCT1 mRNA

NCBI chr 1:42,018,137...42,029,410
Ensembl chr 1:42,018,137...42,029,410

G

myosin light chain 12B

increases expression

triadimefon results in increased expression of MYL12B mRNA

NCBI chr 9:110,873,855...110,888,187

G

myosin light chain 9

decreases expression

triadimefon results in decreased expression of MYL9 mRNA

NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333

G

myosin ID

increases expression

triadimefon results in increased expression of MYO1D mRNA

NCBI chr10:65,489,153...65,765,812
Ensembl chr10:65,489,154...65,766,349

G

N-acetylglutamate synthase

decreases expression

triadimefon results in decreased expression of NAGS mRNA

NCBI chr10:87,098,330...87,102,465
Ensembl chr10:87,098,330...87,102,465

G

nucleosome assembly protein 1-like 3

decreases expression

triadimefon results in decreased expression of NAP1L3 mRNA

NCBI chr X:88,347,595...88,350,393
Ensembl chr X:88,347,598...88,350,393

G

nuclear prelamin A recognition factor

decreases expression

triadimefon results in decreased expression of NARF mRNA

NCBI chr10:106,519,508...106,537,494
Ensembl chr10:106,519,444...106,537,486

G

nuclear autoantigenic sperm protein

increases expression

triadimefon results in increased expression of NASP mRNA

NCBI chr 5:130,057,363...130,083,003
Ensembl chr 5:130,057,363...130,082,928

G

N-myc downstream regulated 1

increases expression

triadimefon results in increased expression of NDRG1 mRNA

NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880

G

NADH:ubiquinone oxidoreductase subunit AB1

decreases expression

triadimefon results in decreased expression of NDUFAB1 mRNA

NCBI chr 1:176,644,696...176,658,131
Ensembl chr 1:176,644,703...176,658,099

G

nebulette

increases expression

triadimefon results in increased expression of NEBL mRNA

NCBI chr17:80,113,891...80,466,331
Ensembl chr17:80,118,543...80,466,210

G

nectin cell adhesion molecule 2

affects expression

triadimefon affects the expression of NECTIN2 mRNA

NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360

G

neuronal differentiation 2

decreases expression

triadimefon results in decreased expression of NEUROD2 mRNA

NCBI chr10:83,323,801...83,327,986
Ensembl chr10:83,324,442...83,327,986

G

nexilin (F actin binding protein)

decreases expression

triadimefon results in decreased expression of NEXN mRNA

NCBI chr 2:241,186,783...241,218,315
Ensembl chr 2:241,186,790...241,218,342

G

NFE2 like bZIP transcription factor 2

increases activity

triadimefon results in increased activity of NFE2L2 protein

PMID:30114225 PMID:30203046

NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737

G

nuclear factor I/A

decreases expression

triadimefon results in decreased expression of NFIA mRNA

NCBI chr 5:112,436,655...112,781,878
Ensembl chr 5:112,436,644...112,775,885

G

nuclear factor, interleukin 3 regulated

affects expression

triadimefon affects the expression of NFIL3 mRNA

NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858

G

NKD inhibitor of WNT signaling pathway 2

decreases expression

triadimefon results in decreased expression of NKD2 mRNA

NCBI chr 1:29,442,898...29,470,839
Ensembl chr 1:29,441,328...29,470,821

G

nicotinamide N-methyltransferase

increases expression

triadimefon results in increased expression of NNMT mRNA

NCBI chr 8:48,928,663...48,947,734
Ensembl chr 8:48,933,598...48,946,655

G

nicotinamide nucleotide transhydrogenase

increases expression

triadimefon results in increased expression of NNT mRNA

NCBI chr 2:51,411,413...51,505,125
Ensembl chr 2:51,411,413...51,504,823

G

NOP58 ribonucleoprotein

increases expression

triadimefon results in increased expression of NOP58 mRNA

NCBI chr 9:61,120,939...61,144,810
Ensembl chr 9:61,120,929...61,144,810

G

natriuretic peptide receptor 3

decreases expression

triadimefon results in decreased expression of NPR3 mRNA

NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955

G

NAD(P)H quinone dehydrogenase 1

affects expression

triadimefon affects the expression of NQO1 mRNA

NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557

G

nuclear receptor subfamily 1, group D, member 2

decreases expression

triadimefon results in decreased expression of NR1D2 mRNA

NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553

G

nuclear receptor subfamily 1, group H, member 3

multiple interactions

NR1H3 gene mutant form inhibits the reaction [triadimefon results in increased expression of BIRC5 mRNA]; NR1H3 gene mutant form inhibits the reaction [triadimefon results in increased expression of CYP2B10 mRNA]; NR1H3 gene mutant form inhibits the reaction [triadimefon results in increased expression of CYP3A11 mRNA]; NR1H3 gene mutant form promotes the reaction [triadimefon results in increased expression of GSTM3 mRNA]

NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722

G

nuclear receptor subfamily 1, group I, member 2

multiple interactions

triadimefon binds to and results in increased activity of NR1I2 protein
[N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with pyrimethanil co-treated with Fenitrothion co-treated with triadimefon co-treated with quinoxyfen co-treated with penconazole] results in increased activity of NR1I2 protein; triadimefon binds to and results in increased activity of NR1I2 protein

PMID:21115097 PMID:25028461

NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658

G

nuclear receptor subfamily 1, group I, member 3

decreases expression
increases activity

triadimefon results in decreased expression of NR1I3 mRNA
triadimefon results in increased activity of NR1I3 protein

PMID:25949234 PMID:30203046

NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906

G

nuclear receptor subfamily 5, group A, member 1

decreases expression

triadimefon results in decreased expression of NR5A1 mRNA; triadimefon results in decreased expression of NR5A1 protein

NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328

G

nuclear receptor binding protein 2

decreases expression

triadimefon results in decreased expression of NRBP2 mRNA

NCBI chr 7:107,798,642...107,805,225
Ensembl chr 7:107,799,497...107,805,230

G

nurim

increases expression

triadimefon results in increased expression of NRM mRNA

NCBI chr20:2,888,321...2,892,804
Ensembl chr20:2,877,567...2,891,802

G

NOP2/Sun RNA methyltransferase family member 7

decreases expression

triadimefon results in decreased expression of NSUN7 mRNA

NCBI chr14:41,878,562...41,935,238
Ensembl chr14:41,879,293...41,934,949

G

nucleoporin 155

increases expression

triadimefon results in increased expression of NUP155 mRNA

NCBI chr 2:57,201,310...57,252,918
Ensembl chr 2:57,201,272...57,254,148

G

nucleoporin 35

increases expression

triadimefon results in increased expression of NUP35 mRNA

NCBI chr 3:65,555,203...65,594,488
Ensembl chr 3:65,558,968...65,585,130

G

nuclear transport factor 2-like export factor 1

increases expression

triadimefon results in increased expression of NXT1 mRNA

NCBI chr 3:136,108,975...136,111,897
Ensembl chr 3:136,108,862...136,111,907

G

odorant binding protein 2A

decreases expression

triadimefon results in decreased expression of OBP2A mRNA

NCBI chr 3:8,505,963...8,509,269
Ensembl chr 3:8,505,990...8,509,269

G

opioid growth factor receptor

decreases expression

triadimefon results in decreased expression of OGFR mRNA

NCBI chr 3:167,703,173...167,709,459
Ensembl chr 3:167,702,695...167,709,473

G

osteomodulin

decreases expression

triadimefon results in decreased expression of OMD mRNA

NCBI chr17:15,060,217...15,068,441
Ensembl chr17:15,060,217...15,068,441

G

one cut homeobox 1

decreases expression

triadimefon results in decreased expression of ONECUT1 mRNA

NCBI chr 8:75,599,432...75,633,598
Ensembl chr 8:75,599,740...75,627,277

G

otogelin-like

decreases expression

triadimefon results in decreased expression of OTOGL mRNA

NCBI chr 7:43,065,800...43,211,400
Ensembl chr 7:43,067,644...43,223,592

G

orthodenticle homeobox 1

affects expression

triadimefon affects the expression of OTX1 mRNA

NCBI chr14:96,082,146...96,089,161
Ensembl chr14:96,082,151...96,089,086

G

prolyl 4-hydroxylase subunit beta

increases expression

triadimefon results in increased expression of P4HB mRNA

NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500

G

poly(A) binding protein, cytoplasmic 1

decreases expression

triadimefon results in decreased expression of PABPC1 mRNA

NCBI chr 7:67,777,438...67,789,731
Ensembl chr 7:67,777,381...67,789,744

G

protein kinase C and casein kinase substrate in neurons 2

increases expression

triadimefon results in increased expression of PACSIN2 mRNA

NCBI chr 7:114,505,525...114,599,087
Ensembl chr 7:114,505,152...114,598,546

G

presequence translocase associated motor 16

increases expression

triadimefon results in increased expression of PAM16 mRNA

NCBI chr10:10,942,534...10,950,654
Ensembl chr10:10,943,001...10,950,649

G

pappalysin

decreases expression

triadimefon results in decreased expression of PAPPA mRNA

NCBI chr 5:78,497,660...78,735,873
Ensembl chr 5:78,498,300...78,730,666

G

3'-phosphoadenosine 5'-phosphosulfate synthase 2

increases expression

triadimefon results in increased expression of PAPSS2 mRNA

NCBI chr 1:230,454,314...230,539,332
Ensembl chr 1:230,454,426...230,539,331

G

pro-apoptotic WT1 regulator

decreases expression

triadimefon results in decreased expression of PAWR mRNA

NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028

G

pyruvate carboxylase

decreases expression

triadimefon results in decreased expression of PC mRNA

NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380

G

protocadherin gamma subfamily C, 3

increases expression

triadimefon results in increased expression of PCDHGC3 mRNA

NCBI chr18:29,633,016...29,667,865
Ensembl chr18:29,493,954...29,667,868

G

phosphodiesterase 11A

decreases expression

triadimefon results in decreased expression of PDE11A mRNA

NCBI chr 3:60,913,562...61,297,154
Ensembl chr 3:60,913,562...61,297,158

G

phosphodiesterase 4A

decreases expression

triadimefon results in decreased expression of PDE4A mRNA

NCBI chr 8:19,690,816...19,753,538
Ensembl chr 8:19,703,290...19,751,961

G

protein disulfide isomerase family A, member 4

increases expression

triadimefon results in increased expression of PDIA4 mRNA

NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107

G

pyridoxal phosphatase

affects expression

triadimefon affects the expression of PDXP mRNA

NCBI chr 7:110,472,515...110,477,963
Ensembl chr 7:110,472,515...110,477,963

G

phosphoglycerate kinase 1

increases expression

triadimefon results in increased expression of PGK1 mRNA

NCBI chr X:71,271,454...71,287,429
Ensembl chr X:71,271,440...71,287,418

G

phosphoinositide-3-kinase interacting protein 1

decreases expression

triadimefon results in decreased expression of PIK3IP1 mRNA

NCBI chr14:78,204,668...78,216,616
Ensembl chr14:78,204,053...78,216,608

G

Pim-1 proto-oncogene, serine/threonine kinase

affects expression

triadimefon affects the expression of PIM1 mRNA

NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174

G

phosphatidylinositol-4-phosphate 5-kinase type 1 beta

increases expression

triadimefon results in increased expression of PIP5K1B mRNA

NCBI chr 1:221,907,220...222,183,672
Ensembl chr 1:221,914,159...222,183,672

G

pyruvate kinase L/R

decreases expression

triadimefon results in decreased expression of PKLR mRNA

NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870

G

phospholipase A and acyltransferase 1

decreases expression

triadimefon results in decreased expression of HRASLS mRNA

NCBI chr11:71,517,492...71,537,142
Ensembl chr11:71,517,493...71,527,020

G

plasminogen activator, tissue type

increases expression

triadimefon results in increased expression of PLAT mRNA

NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223

G

phospholipase C, gamma 1

increases expression

triadimefon results in increased expression of PLCG1 mRNA

NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330

G

phospholipid phosphatase 3

decreases expression

triadimefon results in decreased expression of PPAP2B mRNA

NCBI chr 5:119,927,085...120,002,206
Ensembl chr 5:119,927,085...120,002,205

G

phospholipid phosphatase related 4

decreases expression

triadimefon results in decreased expression of PLPPR4 mRNA

NCBI chr 2:205,371,317...205,412,302
Ensembl chr 2:205,371,322...205,412,302

G

phorbol-12-myristate-13-acetate-induced protein 1

affects expression

triadimefon affects the expression of PMAIP1 mRNA

NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429

G

pinin, desmosome associated protein

decreases expression

triadimefon results in decreased expression of PNN mRNA

NCBI chr 6:76,758,138...76,766,451
Ensembl chr 6:76,758,117...76,766,889

G

proopiomelanocortin

decreases expression

triadimefon results in decreased expression of POMC protein

NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664

G

cytochrome p450 oxidoreductase

increases expression

triadimefon results in increased expression of POR mRNA

NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245

G

POU class 6 homeobox 1

decreases expression

triadimefon results in decreased expression of POU6F1 mRNA

NCBI chr 7:131,677,719...131,700,869
Ensembl chr 7:131,680,141...131,686,843
Ensembl chr 7:131,680,141...131,686,843

G

protein phosphatase 1, regulatory subunit 42

increases expression

triadimefon results in increased expression of PPP1R42 mRNA

NCBI chr 5:9,227,109...9,274,461
Ensembl chr 5:9,227,204...9,274,453

G

protein phosphatase 2, regulatory subunit B, beta

increases expression

triadimefon results in increased expression of PPP2R2B mRNA

NCBI chr18:34,653,716...35,080,889
Ensembl chr18:34,653,721...35,081,025

G

prolyl endopeptidase

increases expression

triadimefon results in increased expression of PREP mRNA

NCBI chr20:48,556,211...48,653,165
Ensembl chr20:48,556,280...48,654,466

G

prickle planar cell polarity protein 1

decreases expression

triadimefon results in decreased expression of PRICKLE1 mRNA

NCBI chr 7:124,639,142...124,735,027
Ensembl chr 7:124,639,142...124,658,113

G

protein kinase AMP-activated catalytic subunit alpha 1

decreases phosphorylation

triadimefon results in decreased phosphorylation of PRKAA1 protein

NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978

G

protein kinase AMP-activated catalytic subunit alpha 2

decreases phosphorylation

triadimefon results in decreased phosphorylation of PRKAA2 protein

NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543

G

protein C, inactivator of coagulation factors Va and VIIIa

increases expression

triadimefon results in increased expression of PROC mRNA

NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133

G

proline dehydrogenase

decreases expression

triadimefon results in decreased expression of PRODH mRNA

NCBI chr11:82,910,043...82,927,305
Ensembl chr11:82,910,137...82,927,305

G

pre-mRNA processing factor 38B

affects expression

triadimefon affects the expression of PRPF38B mRNA

NCBI chr 2:196,553,224...196,562,271
Ensembl chr 2:196,553,225...196,562,250

G

serine protease 41

decreases expression

triadimefon results in decreased expression of PRSS41 mRNA

NCBI chr10:12,865,872...12,873,552
Ensembl chr10:12,865,872...12,873,552

G

presenilin 1

increases expression

triadimefon results in increased expression of PSEN1 mRNA

NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650

G

PC4 and SRSF1 interacting protein 1

increases expression

triadimefon results in increased expression of PSIP1 mRNA

NCBI chr 5:97,847,010...97,879,280
Ensembl chr 5:97,847,015...97,879,257

G

proteasome 20S subunit beta 4

increases expression

triadimefon results in increased expression of PSMB4 mRNA

NCBI chr 2:182,442,757...182,445,532
Ensembl chr 2:182,442,756...182,445,746

G

proteasome 26S subunit, non-ATPase 11

increases expression

triadimefon results in increased expression of PSMD11 mRNA

NCBI chr10:65,433,853...65,479,774
Ensembl chr10:65,433,853...65,479,766

G

proteasome activator subunit 1

increases expression

triadimefon results in increased expression of PSME1 mRNA

NCBI chr15:29,069,012...29,071,888
Ensembl chr15:29,068,729...29,071,890

G

prothymosin alpha

increases expression

triadimefon results in increased expression of PTMA mRNA

NCBI chr 9:87,176,251...87,180,333
Ensembl chr 9:87,176,230...87,180,333

G

protein tyrosine phosphatase, non-receptor type 1

increases expression

triadimefon results in increased expression of PTPN1 mRNA

NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504

G

protein tyrosine phosphatase, receptor type, U

decreases expression

triadimefon results in decreased expression of PTPRU mRNA

NCBI chr 5:143,950,542...144,024,791
Ensembl chr 5:143,950,965...144,024,768

G

peptidyl-tRNA hydrolase 2

increases expression

triadimefon results in increased expression of PTRH2 mRNA

NCBI chr10:71,505,113...71,515,297
Ensembl chr10:71,504,956...71,515,398

G

PVR cell adhesion molecule

increases expression

triadimefon results in increased expression of PVR mRNA

NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715

G

glutaminyl-tRNA synthetase 1

decreases expression

triadimefon results in decreased expression of QARS1 mRNA

NCBI chr 8:109,207,705...109,215,738
Ensembl chr 8:109,207,705...109,215,739

G

R3H domain and coiled-coil containing 1-like

decreases expression

triadimefon results in decreased expression of R3HCC1L mRNA

NCBI chr 1:241,317,199...241,395,240
Ensembl chr 1:241,317,272...241,395,240

G

RAB11 family interacting protein 5

increases expression

triadimefon results in increased expression of RAB11FIP5 mRNA

NCBI chr 4:117,871,301...117,908,819
Ensembl chr 4:117,871,308...117,908,741

G

RAB14, member RAS oncogene family

affects expression

triadimefon affects the expression of RAB14 mRNA

NCBI chr 3:18,501,953...18,523,253
Ensembl chr 3:18,501,963...18,523,172

G

RAB3B, member RAS oncogene family

decreases expression

triadimefon results in decreased expression of RAB3B mRNA

NCBI chr 5:123,629,562...123,697,410
Ensembl chr 5:123,644,423...123,697,401

G

RAB9A, member RAS oncogene family

decreases expression

triadimefon results in decreased expression of RAB9A mRNA

NCBI chr X:27,955,552...28,009,870
Ensembl chr X:27,952,204...28,001,622

G

Rac family small GTPase 2

increases expression

triadimefon analog results in increased expression of RAC2 mRNA; triadimefon results in increased expression of RAC2 mRNA

NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720

G

RAN, member RAS oncogene family

increases expression

triadimefon results in increased expression of RAN mRNA

NCBI chr12:27,674,049...27,678,598
Ensembl chr12:27,674,050...27,678,276

G

RAN binding protein 6

increases expression

triadimefon results in increased expression of RANBP6 mRNA

NCBI chr 1:227,572,394...227,576,915
Ensembl chr 1:227,572,105...227,576,942

G

Rap guanine nucleotide exchange factor 2

increases expression

triadimefon results in increased expression of RAPGEF2 mRNA

NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247

G

retinoic acid receptor, beta

increases expression

triadimefon results in increased expression of RARB mRNA

NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288

G

RB binding protein 8, endonuclease

increases expression

triadimefon results in increased expression of RBBP8 mRNA

NCBI chr18:2,922,985...2,988,851
Ensembl chr18:2,921,286...2,988,846

G

RNA binding motif protein 24

decreases expression

triadimefon results in decreased expression of RBM24 mRNA

NCBI chr17:18,275,681...18,288,231
Ensembl chr17:18,275,688...18,288,102

G

recombination signal binding protein for immunoglobulin kappa J region-like

decreases expression

triadimefon results in decreased expression of RBPJL mRNA

NCBI chr 3:153,134,044...153,147,421
Ensembl chr 3:153,134,140...153,146,513

G

RD3 regulator of GUCY2D

decreases expression

triadimefon results in decreased expression of RD3 mRNA

NCBI chr13:103,551,823...103,562,925
Ensembl chr13:103,552,857...103,562,622

G

refilin A

increases expression

triadimefon results in increased expression of RFLNA mRNA

PMID:22664269 PMID:28263823

NCBI chr12:31,633,360...31,642,313
Ensembl chr12:31,633,361...31,642,317

G

regulatory factor X, 7

decreases expression

triadimefon results in decreased expression of RFX7 mRNA

NCBI chr 8:73,254,051...73,339,209
Ensembl chr 8:73,254,051...73,339,209

G

regulatory factor X-associated ankyrin-containing protein

decreases expression

triadimefon results in decreased expression of RFXANK mRNA

NCBI chr16:19,280,857...19,288,886
Ensembl chr16:19,281,475...19,460,255

G

regulator of cell cycle

decreases expression

triadimefon results in decreased expression of RGCC mRNA

NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141

G

regulator of G-protein signaling 11

decreases expression

triadimefon results in decreased expression of RGS11 mRNA

NCBI chr10:15,222,804...15,231,062
Ensembl chr10:15,222,803...15,231,060

G

regulator of G-protein signaling 19

affects expression

triadimefon affects the expression of RGS19 mRNA

NCBI chr 3:168,804,532...168,813,035
Ensembl chr 3:168,804,874...168,810,097

G

ras homolog family member B

decreases expression

triadimefon analog results in decreased expression of RHOB mRNA

NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108

G

ras homolog family member C

decreases expression

triadimefon analog results in decreased expression of RHOC mRNA; triadimefon results in decreased expression of RHOC mRNA

NCBI chr 2:192,287,065...192,293,292
Ensembl chr 2:192,287,130...192,295,306

G

ring finger protein 144B

decreases expression

triadimefon results in decreased expression of RNF144B mRNA

NCBI chr17:17,431,271...17,580,687
Ensembl chr17:17,432,786...17,562,760

G

RNA binding protein with serine rich domain 1

increases expression

triadimefon results in increased expression of RNPS1 mRNA

NCBI chr10:13,445,516...13,455,858
Ensembl chr10:13,445,653...13,455,858

G

RAR-related orphan receptor B

increases expression

triadimefon results in increased expression of RORB mRNA

NCBI chr 1:216,363,629...216,544,390
Ensembl chr 1:216,363,629...216,544,390

G

ribosomal protein L13A

increases expression

triadimefon results in increased expression of RPL13A mRNA

NCBI chr 1:95,609,374...95,612,557
Ensembl chr 1:95,609,370...95,620,463

G

ribosomal protein L34

decreases expression

triadimefon results in decreased expression of RPL34 mRNA

NCBI chr 2:219,284,373...219,288,108
Ensembl chr 2:219,284,382...219,288,111

G

ribosomal protein L38

increases expression

triadimefon results in increased expression of RPL38 mRNA

NCBI chr10:99,701,330...99,705,004
Ensembl chr10:99,701,362...99,705,004
Ensembl chr14:99,701,362...99,705,004
Ensembl chr 3:99,701,362...99,705,004
Ensembl chr 2:99,701,362...99,705,004
Ensembl chr16:99,701,362...99,705,004

G

ribonuclease P/MRP subunit p21

increases expression

triadimefon results in increased expression of RPP21 mRNA

NCBI chr20:2,018,170...2,020,100
Ensembl chr20:2,018,147...2,020,106

G

ribosomal protein S13

decreases expression

triadimefon results in decreased expression of RPS13 mRNA

NCBI chr 1:170,572,925...170,575,355
Ensembl chr 1:170,572,921...170,575,355
Ensembl chr 3:170,572,921...170,575,355

G

ribosomal protein S23

decreases expression

triadimefon results in decreased expression of RPS23 mRNA

NCBI chr 2:22,079,339...22,080,909
Ensembl chr 2:22,079,302...22,080,918

G

ribosomal protein s25

decreases expression

triadimefon results in decreased expression of RPS25 mRNA

NCBI chr 8:44,733,623...44,735,999
Ensembl chr 8:44,733,029...44,737,271

G

ribosomal RNA processing 7 homolog A

decreases expression

triadimefon results in decreased expression of RRP7A mRNA

NCBI chr 7:114,262,929...114,272,817
Ensembl chr 7:114,256,472...114,272,817

G

arginine and serine rich protein 1

affects expression

triadimefon affects the expression of RSRP1 mRNA

NCBI chr 5:147,147,774...147,151,523
Ensembl chr 5:147,147,784...147,151,523

G

RUN domain containing 3A

decreases expression

triadimefon results in decreased expression of RUNDC3A mRNA

NCBI chr10:87,352,624...87,361,767
Ensembl chr10:87,352,646...87,361,765

G

S100 calcium binding protein A8

increases expression

triadimefon results in increased expression of S100A8 mRNA

NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643

G

Sin3A-associated protein 25

decreases expression

triadimefon results in decreased expression of SAP25 mRNA

NCBI chr12:19,055,762...19,057,425
Ensembl chr12:19,055,763...19,076,089

G

stearoyl-Coenzyme A desaturase 2

decreases expression

triadimefon results in decreased expression of SCD2 mRNA; triadimefon results in decreased expression of SCD2 protein

NCBI chr 1:243,169,171...243,182,231
Ensembl chr 1:243,169,236...243,182,232

G

syndecan 1

increases expression

triadimefon results in increased expression of SDC1 mRNA

NCBI chr 6:31,562,799...31,585,267
Ensembl chr 6:31,562,739...31,585,264

G

SEC61 translocon subunit alpha 1

decreases expression

triadimefon results in decreased expression of SEC61A1 mRNA

NCBI chr 4:120,973,519...120,987,871
Ensembl chr 4:120,960,626...120,987,925

G

Sec61 translocon subunit gamma

increases expression

triadimefon results in increased expression of SEC61G mRNA

NCBI chr14:90,899,766...90,906,143
Ensembl chr14:90,899,768...90,906,162

G

semaphorin 6D

increases expression

triadimefon results in increased expression of SEMA6D mRNA

NCBI chr 3:111,883,415...111,941,100
Ensembl chr 3:111,883,872...111,941,094

G

serpin family A member 1

affects expression

triadimefon affects the expression of SERPINA1 mRNA

NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339

G

serpin family A member 9

decreases expression

triadimefon results in decreased expression of SERPINA9 mRNA

NCBI chr 6:122,918,819...122,936,000
Ensembl chr 6:122,918,880...122,936,000

G

serpin family E member 1

decreases expression

triadimefon results in decreased expression of SERPINE1 mRNA

NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657

G

serpin family F member 1

increases expression

triadimefon results in increased expression of SERPINF1 mRNA

NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646

G

splicing factor 1

increases expression

triadimefon results in increased expression of SF1 mRNA

NCBI chr 1:203,670,016...203,683,432
Ensembl chr 1:203,670,018...203,684,330

G

splicing factor proline and glutamine rich

increases expression

triadimefon results in increased expression of SFPQ mRNA

NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472

G

sideroflexin 2

decreases expression

triadimefon results in decreased expression of SFXN2 mRNA

NCBI chr 1:245,447,014...245,459,312
Ensembl chr 1:245,447,015...245,468,411
Ensembl chr 1:245,447,015...245,468,411

G

SH3 domain binding glutamate-rich protein like 3

increases expression

triadimefon results in increased expression of SH3BGRL3 mRNA

NCBI chr 5:146,354,152...146,355,525
Ensembl chr 5:146,354,152...146,355,331

G

SH3 and SYLF domain containing 1

decreases expression

triadimefon results in decreased expression of SH3YL1 mRNA

NCBI chr 6:47,522,098...47,565,858
Ensembl chr 6:47,522,091...47,565,858

G

sonic hedgehog signaling molecule

decreases expression

triadimefon results in decreased expression of SHH mRNA

NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170

G

src kinase associated phosphoprotein 2

affects expression

triadimefon affects the expression of SKAP2 mRNA

NCBI chr 4:80,948,832...81,100,900
Ensembl chr 4:80,950,580...81,100,891

G

stem-loop histone mRNA binding protein

decreases expression

triadimefon results in decreased expression of SLBP mRNA

NCBI chr14:77,071,441...77,081,911
Ensembl chr14:77,071,632...77,081,906

G

solute carrier family 12 member 5

decreases expression

triadimefon results in decreased expression of SLC12A5 mRNA

NCBI chr 3:153,696,517...153,735,801
Ensembl chr 3:153,696,517...153,735,765

G

solute carrier family 12, member 6

decreases expression

triadimefon results in decreased expression of SLC12A6 mRNA

NCBI chr 3:99,071,577...99,170,266
Ensembl chr 3:99,071,391...99,170,258

G

solute carrier family 17, member 2

decreases expression

triadimefon results in decreased expression of SLC17A2 mRNA

NCBI chr17:41,318,312...41,339,012
Ensembl chr17:41,319,701...41,336,325

G

solute carrier family 1 member 7

decreases expression

triadimefon results in decreased expression of SLC1A7 mRNA

NCBI chr 5:122,731,003...122,775,139
Ensembl chr 5:122,731,003...122,775,134

G

solute carrier family 22 member 7

increases expression

triadimefon results in increased expression of SLC22A7 mRNA

NCBI chr 9:14,547,073...14,554,354
Ensembl chr 9:14,547,849...14,553,921

G

solute carrier family 25 member 25

increases expression

triadimefon results in increased expression of SLC25A25 mRNA

NCBI chr 3:15,708,702...15,742,195
Ensembl chr 3:15,708,703...15,742,216

G

solute carrier family 25 member 29

increases expression

triadimefon results in increased expression of SLC25A29 mRNA

NCBI chr 6:127,742,027...127,752,915
Ensembl chr 6:127,742,033...127,752,940

G

solute carrier family 2 member 5

decreases expression

triadimefon results in decreased expression of SLC2A5 mRNA

NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:160,583,234...160,611,106

G

solute carrier family 3 member 2

increases expression

triadimefon results in increased expression of SLC3A2 mRNA

NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931

G

solute carrier family 52 member 2

increases expression

triadimefon results in increased expression of SLC52A2 mRNA

NCBI chr 7:108,246,003...108,267,642
Ensembl chr 7:108,262,612...108,268,034

G

solute carrier family 5 member 8

increases expression

triadimefon results in increased expression of SLC5A8 mRNA

NCBI chr 7:23,272,891...23,313,811
Ensembl chr 7:23,272,427...23,314,642

G

solute carrier family 6 member 13

decreases expression

triadimefon results in decreased expression of SLC6A13 mRNA

NCBI chr 4:154,539,246...154,577,784
Ensembl chr 4:154,540,468...154,576,152

G

solute carrier family 9 member A5

decreases expression

triadimefon results in decreased expression of SLC9A5 mRNA

NCBI chr19:33,225,481...33,246,913
Ensembl chr19:33,226,816...33,246,903

G

solute carrier organic anion transporter family, member 1a4

increases expression

triadimefon results in increased expression of SLCO1A4 mRNA

PMID:16643972 PMID:16730040 PMID:19409404 PMID:19423681 PMID:23970803

NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573

G

single-pass membrane protein with coiled-coil domains 4

increases expression

triadimefon results in increased expression of SMCO4 mRNA

NCBI chr 8:12,313,235...12,365,534
Ensembl chr 8:12,313,328...12,365,529

G

sphingomyelin phosphodiesterase 3

increases expression

triadimefon results in increased expression of SMPD3 mRNA

NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749

G

small nuclear ribonucleoprotein polypeptide G

increases expression

triadimefon results in increased expression of SNRPG mRNA

NCBI chr 4:118,812,278...118,819,827
Ensembl chr 4:118,812,252...118,819,826

G

sorting nexin 24

decreases expression

triadimefon results in decreased expression of SNX24 mRNA

NCBI chr18:46,670,987...46,826,070
Ensembl chr18:46,671,443...46,826,068

G

sorting nexin 27

decreases expression

triadimefon results in decreased expression of SNX27 mRNA

NCBI chr 2:182,135,904...182,218,906
Ensembl chr 2:182,135,905...182,218,906

G

sorting nexin 33

decreases expression

triadimefon results in decreased expression of SNX33 mRNA

NCBI chr 8:57,315,861...57,328,522
Ensembl chr 8:57,317,161...57,327,538

G

superoxide dismutase 2

decreases expression

triadimefon results in decreased expression of SOD2 mRNA; triadimefon results in decreased expression of SOD2 protein

NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189

G

sortilin-related VPS10 domain containing receptor 1

increases expression

triadimefon results in increased expression of SORCS1 mRNA

NCBI chr 1:249,080,662...249,594,520
Ensembl chr 1:249,081,355...249,594,507

G

SRY-box transcription factor 13

affects expression

triadimefon affects the expression of SOX13 mRNA

NCBI chr13:44,831,097...44,875,522
Ensembl chr13:44,831,085...44,875,762

G

sperm associated antigen 6

decreases expression

triadimefon results in decreased expression of SPAG6 mRNA

NCBI chr17:81,352,372...81,401,504
Ensembl chr17:81,349,084...81,401,501

G

spondin 1

increases expression

triadimefon results in increased expression of SPON1 mRNA

NCBI chr 1:167,929,049...168,228,239
Ensembl chr 1:167,928,972...168,228,226

G

squalene epoxidase

affects expression
increases expression

triadimefon affects the expression of SQLE mRNA
triadimefon results in increased expression of SQLE mRNA

PMID:17178688 PMID:19409404 PMID:19423681 PMID:21195148

NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618

G

steroid 5 alpha-reductase 1

decreases expression

triadimefon results in decreased expression of SRD5A1 mRNA

NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461

G

serine and arginine rich splicing factor 10

increases expression

triadimefon results in increased expression of SRSF10 mRNA

NCBI chr 5:148,088,759...148,102,964
Ensembl chr 5:148,088,823...148,101,768

G

serine and arginine rich splicing factor 11

affects expression

triadimefon affects the expression of SRSF11 mRNA

NCBI chr 2:247,074,623...247,101,460
Ensembl chr 2:247,074,631...247,101,425

G

signal sequence receptor subunit 3

increases expression

triadimefon results in increased expression of SSR3 mRNA

NCBI chr 2:149,605,005...149,625,069
Ensembl chr 2:149,605,005...149,625,132

G

somatostatin receptor 2

increases expression

triadimefon results in increased expression of SSTR2 mRNA

NCBI chr10:98,664,204...98,671,370
Ensembl chr10:98,664,216...98,674,351

G

SSU72 homolog, RNA polymerase II CTD phosphatase

increases expression

triadimefon results in increased expression of SSU72 mRNA

NCBI chr 5:166,312,267...166,343,432
Ensembl chr 5:166,313,650...166,343,429

G

STAG1 cohesin complex component

increases expression

triadimefon results in increased expression of STAG1 mRNA

NCBI chr 8:101,179,039...101,564,684
Ensembl chr 8:101,179,039...101,564,677

G

STAM binding protein-like 1

increases expression

triadimefon results in increased expression of STAMBPL1 mRNA

NCBI chr 1:231,699,620...231,745,034
Ensembl chr 1:231,699,995...231,745,032

G

steroidogenic acute regulatory protein

decreases expression
increases expression

triadimefon results in decreased expression of STAR mRNA; triadimefon results in decreased expression of STAR protein
triadimefon results in increased expression of STAR mRNA; triadimefon results in increased expression of STAR protein

PMID:34508824 PMID:36179991

NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672

G

signal transducer and activator of transcription 3

decreases expression

triadimefon results in decreased expression of STAT3 protein

NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057

G

signal transducer and activator of transcription 5B

decreases expression
decreases activity

triadimefon results in decreased expression of STAT5B mRNA
triadimefon results in decreased activity of STAT5B protein

PMID:19363144 PMID:30114225

NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668

G

sulfatase 1

decreases expression

triadimefon results in decreased expression of SULF1 mRNA

NCBI chr 5:6,362,894...6,526,174
Ensembl chr 5:6,362,911...6,525,584

G

sulfotransferase family 1E member 1

decreases expression

triadimefon results in decreased expression of SULT1E1 mRNA

NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275

G

syncoilin, intermediate filament protein

decreases expression

triadimefon results in decreased expression of SYNC mRNA

NCBI chr 5:141,631,837...141,656,184
Ensembl chr 5:141,632,367...141,688,659

G

tachykinin, precursor 1

increases expression

triadimefon results in increased expression of TAC1 mRNA

NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178

G

transgelin

decreases expression

triadimefon results in decreased expression of TAGLN mRNA

NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668

G

Tax1 binding protein 3

increases expression

triadimefon results in increased expression of TAX1BP3 mRNA

NCBI chr10:57,795,845...57,800,363
Ensembl chr10:57,795,382...57,800,363

G

transcription factor 24

increases expression

triadimefon results in increased expression of TCF24 mRNA

NCBI chr 5:9,274,659...9,282,876
Ensembl chr 5:9,227,131...9,279,636

G

tudor domain containing 7

increases expression

triadimefon results in increased expression of TDRD7 mRNA

NCBI chr 5:60,238,742...60,312,548
Ensembl chr 5:60,238,678...60,312,544

G

transcription factor AP-2 gamma

affects expression

triadimefon affects the expression of TFAP2C mRNA

NCBI chr 3:161,315,114...161,322,998
Ensembl chr 3:161,315,031...161,322,995

G

transforming growth factor, beta 1

decreases expression

triadimefon results in decreased expression of TGFB1 mRNA; triadimefon results in decreased expression of TGFB1 protein

NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847

G

transforming growth factor, beta 2

decreases expression

triadimefon results in decreased expression of TGFB2 mRNA

PMID:18976680 PMID:26705709

NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405

G

transforming growth factor, beta receptor 1

decreases expression

triadimefon results in decreased expression of TGFBR1 mRNA

NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777

G

THAP domain containing 11

affects expression

triadimefon affects the expression of THAP11 mRNA

NCBI chr19:33,746,977...33,748,794
Ensembl chr19:33,746,854...33,749,540

G

thrombospondin 2

affects expression

triadimefon affects the expression of THBS2 mRNA

NCBI chr 1:55,670,394...55,699,789
Ensembl chr 1:55,670,394...55,699,789

G

TIMP metallopeptidase inhibitor 4

decreases expression

triadimefon results in decreased expression of TIMP4 mRNA

NCBI chr 4:148,306,021...148,312,558
Ensembl chr 4:148,304,490...148,312,558

G

TLC domain containing 3A

affects expression

triadimefon affects the expression of TLCD3A mRNA

NCBI chr10:61,057,470...61,065,293
Ensembl chr10:61,058,042...61,065,283

G

tolloid-like 1

decreases expression

triadimefon results in decreased expression of TLL1 mRNA

NCBI chr16:25,509,146...25,710,330
Ensembl chr16:25,509,146...25,709,543

G

transmembrane protein 229B

decreases expression

triadimefon results in decreased expression of TMEM229B mRNA

NCBI chr 6:97,771,645...97,819,582
Ensembl chr 6:97,775,332...97,819,489

G

transmembrane protein 45b

decreases expression

triadimefon results in decreased expression of TMEM45B mRNA

NCBI chr 8:29,865,276...29,910,453
Ensembl chr 8:29,865,278...29,910,453

G

transmembrane protein 86B

decreases expression

triadimefon results in decreased expression of TMEM86B mRNA

NCBI chr 1:69,218,109...69,220,474
Ensembl chr 1:69,218,608...69,220,124

G

transmembrane protein 88

increases expression

triadimefon results in increased expression of TMEM88 mRNA

NCBI chr10:54,118,752...54,120,447
Ensembl chr10:54,118,752...54,120,447

G

tropomodulin 1

increases expression

triadimefon results in increased expression of TMOD1 mRNA

NCBI chr 5:60,316,445...60,393,957
Ensembl chr 5:60,338,512...60,393,956

G

thymopoietin

increases expression

triadimefon results in increased expression of TMPO mRNA

NCBI chr 7:25,642,752...25,667,756
Ensembl chr 7:25,586,725...25,667,727

G

TNF superfamily member 15

decreases expression

triadimefon results in decreased expression of TNFSF15 mRNA

NCBI chr 5:77,134,885...77,156,171
Ensembl chr 5:77,139,878...77,156,228

G

translocase of outer mitochondrial membrane 5

increases expression

triadimefon results in increased expression of TOMM5 mRNA

NCBI chr 5:59,362,360...59,365,191
Ensembl chr 5:59,362,240...59,365,269

G

translocase of outer mitochondrial membrane 7

increases expression

triadimefon results in increased expression of TOMM7 mRNA

NCBI chr 4:11,305,122...11,311,963
Ensembl chr 4:11,305,110...11,311,962

G

tropomyosin 1

decreases expression

triadimefon results in decreased expression of TPM1 mRNA

NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802

G

translocation associated membrane protein 1

increases expression

triadimefon results in increased expression of TRAM1 mRNA

NCBI chr 5:5,642,579...5,667,666
Ensembl chr 5:5,642,546...5,686,971

G

tribbles pseudokinase 1

decreases expression

triadimefon results in decreased expression of TRIB1 mRNA

NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731

G

tripartite motif-containing 41

decreases expression

triadimefon results in decreased expression of TRIM41 mRNA

NCBI chr10:33,175,213...33,186,472
Ensembl chr10:33,175,213...33,186,694

G

tripartite motif-containing 59

affects expression

triadimefon affects the expression of TRIM59 mRNA

NCBI chr 2:153,269,210...153,281,185
Ensembl chr 2:153,268,584...153,281,031

G

tRNA methyltransferase 10A

increases expression

triadimefon results in increased expression of TRMT10A mRNA

NCBI chr 2:226,669,445...226,684,166
Ensembl chr 2:226,669,832...226,684,151

G

tRNA methyltransferase 61A

increases expression

triadimefon results in increased expression of TRMT61A mRNA

NCBI chr 6:130,737,230...130,743,251
Ensembl chr 6:130,737,219...130,743,243

G

thyroid stimulating hormone receptor

increases expression

triadimefon results in increased expression of TSHR mRNA

NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538

G

tetraspanin 13

increases expression

triadimefon results in increased expression of TSPAN13 mRNA

NCBI chr 6:52,738,748...52,765,503
Ensembl chr 6:52,738,758...52,765,547

G

tetraspanin 15

increases expression

triadimefon results in increased expression of TSPAN15 mRNA

NCBI chr20:30,130,528...30,174,912
Ensembl chr20:30,130,530...30,174,930

G

tetraspanin 9

increases expression

triadimefon results in increased expression of TSPAN9 mRNA

NCBI chr 4:160,813,879...160,995,574
Ensembl chr 4:160,813,879...160,995,501

G

translocator protein

decreases expression

triadimefon results in decreased expression of TSPO mRNA

NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450

G

thiosulfate sulfurtransferase

decreases expression

triadimefon results in decreased expression of TST mRNA

NCBI chr 7:109,948,061...109,955,378
Ensembl chr 7:109,948,062...109,957,216

G

tubulin, alpha 1A

decreases expression

triadimefon results in decreased expression of TUBA1A mRNA

NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186

G

tubulin, beta 2A class IIa

increases expression

triadimefon results in increased expression of TUBB2A mRNA

NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714

G

tubulin, beta 5 class I

increases expression

triadimefon results in increased expression of TUBB5 mRNA

NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940

G

thioredoxin reductase 1

affects expression

triadimefon affects the expression of TXNRD1 mRNA

NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863

G

ubiquitin C

affects expression

triadimefon affects the expression of UBC mRNA

NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925

G

ubiquilin 2

increases expression

triadimefon results in increased expression of UBQLN2 mRNA

NCBI chr X:17,853,086...17,856,505
Ensembl chr X:17,853,114...17,856,505

G

UBX domain protein 6

decreases expression

triadimefon results in decreased expression of UBXN6 mRNA

NCBI chr 9:900,883...906,047
Ensembl chr 9:900,884...906,124

G

UDP glucuronosyltransferase family 1 member A1

increases expression

triadimefon results in increased expression of UGT1A1 mRNA

PMID:19409404 PMID:19423681

NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

UDP glucuronosyltransferase family 1 member A6

increases expression

triadimefon results in increased expression of UGT1A6 mRNA

NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

UDP glucuronosyltransferase family 2 member A1

increases expression

triadimefon results in increased expression of UGT2A1 mRNA

NCBI chr14:20,521,018...20,545,934
Ensembl chr14:20,517,951...20,545,531

G

UDP glucuronosyltransferase 2 family, polypeptide B1

increases expression

triadimefon results in increased expression of UGT2B1 mRNA; triadimefon results in increased expression of UGT2B17 mRNA

PMID:16643972 PMID:17178689 PMID:19409404 PMID:19423681

NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986

G

upstream transcription factor 1

decreases expression

triadimefon results in decreased expression of USF1 mRNA

NCBI chr13:83,845,230...83,854,875
Ensembl chr13:83,822,035...83,854,885

G

vomeronasal 2 receptor, 72

decreases expression

triadimefon results in decreased expression of VOM2R72 mRNA

NCBI chr14:887,435...894,893
Ensembl chr14:803,326...895,020

G

von Willebrand factor

decreases expression

triadimefon results in decreased expression of VWF mRNA; triadimefon results in decreased expression of VWF protein

NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539

G

WD repeat domain 46

affects expression

triadimefon affects the expression of WDR46 mRNA

NCBI chr20:4,937,845...4,945,796
Ensembl chr20:4,937,847...4,946,535

G

WAP four-disulfide core domain 1

decreases expression

triadimefon results in decreased expression of WFDC1 mRNA

NCBI chr19:47,720,191...47,739,121
Ensembl chr19:47,720,423...47,739,108

G

xylosyltransferase 2

decreases expression

triadimefon results in decreased expression of XYLT2 mRNA

NCBI chr10:79,605,910...79,619,482
Ensembl chr10:79,606,007...79,619,391

G

yrdC N(6)-threonylcarbamoyltransferase domain containing

increases expression

triadimefon results in increased expression of YRDC mRNA

NCBI chr 5:137,110,244...137,115,127
Ensembl chr 5:137,110,279...137,115,120

G

YTH N6-methyladenosine RNA binding protein F2

increases expression

triadimefon results in increased expression of YTHDF2 mRNA

NCBI chr 5:144,381,426...144,407,126
Ensembl chr 5:144,381,431...144,408,144

G

zinc finger CCCH type containing 3

decreases expression

triadimefon results in decreased expression of ZC3H3 mRNA

NCBI chr 7:107,440,694...107,525,451
Ensembl chr 7:107,440,694...107,525,451

G

zinc finger DHHC-type palmitoyltransferase 2

increases expression

triadimefon results in increased expression of ZDHHC2 mRNA

NCBI chr16:51,808,465...51,878,060
Ensembl chr16:51,808,468...51,878,060

G

zinc finger protein 157

decreases expression

triadimefon results in decreased expression of ZFP157 mRNA

NCBI chr12:16,248,230...16,279,459
Ensembl chr12:16,248,230...16,270,698

G

zinc finger protein 322a

affects expression

triadimefon affects the expression of ZFP322A mRNA

NCBI chr17:41,773,789...41,789,654
Ensembl chr17:41,773,782...41,790,078

G

zinc finger protein 410

affects expression

triadimefon affects the expression of ZFP410 mRNA

NCBI chr 6:103,963,265...103,990,252
Ensembl chr 6:103,964,060...103,990,225

G

zinc finger protein 428

decreases expression

triadimefon results in decreased expression of ZFP428 mRNA

NCBI chr 1:80,099,520...80,108,875
Ensembl chr 1:80,099,441...80,108,870

G

zinc finger protein 46

decreases expression

triadimefon results in decreased expression of ZFP46 mRNA

NCBI chr 5:148,519,398...148,529,903
Ensembl chr 5:148,520,855...148,529,459

G

zinc finger protein 503

affects expression

triadimefon affects the expression of ZFP503 mRNA

NCBI chr15:2,313,060...2,316,848
Ensembl chr15:2,313,060...2,316,848

G

zinc finger protein 606

decreases expression

triadimefon results in decreased expression of ZFP606 mRNA

NCBI chr 1:72,981,920...73,022,423
Ensembl chr 1:72,981,989...73,008,072

G

zinc finger protein 647

affects expression

triadimefon affects the expression of ZFP647 mRNA

NCBI chr 7:108,632,248...108,649,264
Ensembl chr 7:108,632,250...108,637,433

G

zinc finger protein 703

increases expression

triadimefon results in increased expression of ZFP703 mRNA

NCBI chr16:65,076,507...65,080,677
Ensembl chr16:65,076,507...65,080,677

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	19898
role	19868
application	19714
NMR chemical shift reference compound	18086
ammonia	17885
organic amino compound	17885
hemiaminal ether	654
1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one	630
(R)-triadimefon +	630
(S)-triadimefon +	630
Path 2
Term	Annotations
CHEBI ontology	19898
subatomic particle	19896
composite particle	19896
hadron	19896
baryon	19896
nucleon	19896
atomic nucleus	19896
atom	19896
main group element atom	19835
main group molecular entity	19835
s-block molecular entity	19670
hydrogen molecular entity	19651
hydrides	19158
inorganic hydride	18176
pnictogen hydride	18166
nitrogen hydride	18079
azane	17886
ammonia	17885
organic amino compound	17885
hemiaminal	730
hemiaminal ether	654
1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one	630
(R)-triadimefon +	630
(S)-triadimefon +	630

paths to the root