Plppr4 (phospholipid phosphatase related 4) - Rat Genome Database

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Gene: Plppr4 (phospholipid phosphatase related 4) Rattus norvegicus
Analyze
Symbol: Plppr4
Name: phospholipid phosphatase related 4
RGD ID: 727806
Description: Enables lipid phosphatase activity and lysophosphatidic acid phosphatase activity. Involved in axonogenesis and phospholipid dephosphorylation. Located in external side of plasma membrane. Orthologous to human PLPPR4 (phospholipid phosphatase related 4); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; alpha-Zearalanol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2-lysophosphatidate phosphatase PLPPR4; brain-specific phosphatidic acid phosphatase-like protein 1; inactive 2-lysophosphatidate phosphatase PLPPR4; lipid phosphate phosphatase-related protein type 4; Lppr4; phospholipid phosphatase-related protein type 4; plasticity related gene 1; plasticity-related gene 1; Prg-1; Prg1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82208,056,206 - 208,097,191 (-)NCBIGRCr8
mRatBN7.22205,371,317 - 205,412,302 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2205,371,322 - 205,412,302 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2213,018,609 - 213,059,602 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02210,933,198 - 210,974,196 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02205,751,648 - 205,792,638 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02220,298,239 - 220,341,863 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2220,298,245 - 220,341,866 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02238,365,252 - 238,405,892 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42213,686,578 - 213,727,831 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12213,649,335 - 213,690,585 (-)NCBI
Celera2197,848,561 - 197,889,304 (-)NCBICelera
Cytogenetic Map2q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 20 of 53 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Plppr4Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of PLPPR4 mRNACTDPMID:21215274
Plppr4Rat4,4'-sulfonyldiphenol decreases methylationISORGD:16165516480464bisphenol S results in decreased methylation of PLPPR4 exonCTDPMID:33297965
Plppr4Ratacrylamide increases expressionEXP 6480464Acrylamide results in increased expression of PLPPR4 mRNACTDPMID:28959563
Plppr4Ratall-trans-retinoic acid decreases expressionISORGD:16050996480464Tretinoin results in decreased expression of PLPPR4 mRNACTDPMID:23724009
Plppr4Ratalpha-Zearalanol multiple interactionsEXP 6480464[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of PLPPR4 mRNACTDPMID:35163327
Plppr4Ratamitrole decreases expressionEXP 6480464Amitrole results in decreased expression of PLPPR4 mRNACTDPMID:38685447
Plppr4Ratatrazine affects methylationEXP 6480464Atrazine affects the methylation of PLPPR4 geneCTDPMID:35440735
Plppr4Ratbenzo[a]pyrene increases methylationISORGD:16050996480464Benzo(a)pyrene results in increased methylation of PLPPR4 exonCTDPMID:27901495
Plppr4Ratbenzo[a]pyrene affects methylationISORGD:16050996480464Benzo(a)pyrene affects the methylation of PLPPR4 3' UTR; Benzo(a)pyrene affects the methylation of PLPPR4 promoterCTDPMID:27901495
Plppr4Ratbenzo[a]pyrene diol epoxide I increases expressionISORGD:160509964804647,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of PLPPR4 mRNACTDPMID:20382639
Plppr4Ratbis(2-ethylhexyl) phthalate decreases expressionISORGD:16050996480464Diethylhexyl Phthalate results in decreased expression of PLPPR4 mRNACTDPMID:31163220
Plppr4Ratbis(2-ethylhexyl) phthalate increases expressionISORGD:16165516480464Diethylhexyl Phthalate results in increased expression of PLPPR4 mRNACTDPMID:33162236
Plppr4Ratbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of PLPPR4 mRNACTDPMID:25181051|PMID:30816183|PMID:34947998
Plppr4Ratbisphenol A increases expressionISORGD:16050996480464bisphenol A results in increased expression of PLPPR4 mRNACTDPMID:29275510
Plppr4Ratcadmium atom multiple interactionsISORGD:16050996480464[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PLPPR4 more ...CTDPMID:35301059
Plppr4Ratcadmium dichloride increases expressionEXP 6480464Cadmium Chloride results in increased expression of PLPPR4 mRNACTDPMID:33453195
Plppr4Ratcadmium dichloride multiple interactionsISORGD:16050996480464[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PLPPR4 more ...CTDPMID:35301059
Plppr4RatCuprizon decreases expressionEXP 6480464Cuprizone results in decreased expression of PLPPR4 mRNACTDPMID:26577399
Plppr4Ratdecabromodiphenyl ether decreases expressionEXP 6480464decabromobiphenyl ether results in decreased expression of PLPPR4 mRNACTDPMID:23640034
Plppr4Ratdibutyl phthalate decreases expressionEXP 6480464Dibutyl Phthalate results in decreased expression of PLPPR4 mRNACTDPMID:21266533

1 to 20 of 53 rows

Biological Process
1 to 20 of 23 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Plppr4Rataxonogenesis  IDA 1299556 RGD 
Plppr4Rataxonogenesis involved_inIBAPANTHER:PTN002563145|RGD:7278061600115GO_REF:0000033GO_CentralGO_REF:0000033
Plppr4RatG protein-coupled receptor signaling pathway acts_upstream_ofISSUniProtKB:Q7TME01600115GO_REF:0000024UniProtGO_REF:0000024
Plppr4RatG protein-coupled receptor signaling pathway acts_upstream_ofIEAUniProtKB:Q7TME0|ensembl:ENSMUSP000000523061600115GO_REF:0000107EnsemblGO_REF:0000107
Plppr4RatG protein-coupled receptor signaling pathway acts_upstream_ofISORGD:16165511624291 PMID:19766573RGDPMID:19766573
Plppr4Ratinner ear development acts_upstream_of_or_withinIEAUniProtKB:Q7TME0|ensembl:ENSMUSP000000523061600115GO_REF:0000107EnsemblGO_REF:0000107
Plppr4Ratinner ear development acts_upstream_of_or_withinISORGD:16165511624291 PMID:21795542RGDPMID:21795542
Plppr4Ratlipid import into cell involved_inIEAUniProtKB:Q7TME0|ensembl:ENSMUSP000000523061600115GO_REF:0000107EnsemblGO_REF:0000107
Plppr4Ratlipid import into cell involved_inISORGD:16165511624291 PMID:26671989RGDPMID:26671989
Plppr4Ratlipid import into cell involved_inISSUniProtKB:Q7TME01600115GO_REF:0000024UniProtGO_REF:0000024
Plppr4Ratmodulation of chemical synaptic transmission involved_inISORGD:16165511624291 PMID:26671989, PMID:27453502RGDPMID:26671989|PMID:27453502
Plppr4Ratmodulation of chemical synaptic transmission involved_inIEAUniProtKB:Q7TME0|ensembl:ENSMUSP000000523061600115GO_REF:0000107EnsemblGO_REF:0000107
Plppr4Ratphospholipid dephosphorylation  IDA 1299556 RGD 
Plppr4Ratphospholipid dephosphorylation involved_inIBAMGI:108412|PANTHER:PTN000017950|RGD:621832|RGD:727806|UniProtKB:O14494|UniProtKB:O14495|UniProtKB:O43688|UniProtKB:P60588|UniProtKB:Q5VZY2|UniProtKB:Q8NEB51600115GO_REF:0000033GO_CentralGO_REF:0000033
Plppr4Ratphospholipid dephosphorylation NOT|involved_inISORGD:16050991624291 PMID:15280885RGDPMID:15280885
Plppr4Ratphospholipid metabolic process involved_inIEAInterPro:IPR0432161600115GO_REF:0000002InterProGO_REF:0000002
Plppr4Ratphospholipid metabolic process involved_inIBAMGI:108412|MGI:1915166|PANTHER:PTN000017950|RGD:621832|SGD:S000002692|SGD:S000002911|UniProtKB:O14494|UniProtKB:O14495|UniProtKB:O43688|UniProtKB:P605881600115GO_REF:0000033GO_CentralGO_REF:0000033
Plppr4Ratregulation of postsynapse organization involved_inIEAUniProtKB:Q7TME0|ensembl:ENSMUSP000000523061600115GO_REF:0000107EnsemblGO_REF:0000107
Plppr4Ratregulation of postsynapse organization involved_inISORGD:16165511624291 PMID:27453502RGDPMID:27453502
Plppr4Ratregulation of synaptic transmission, glutamatergic involved_inIEAUniProtKB:Q7TME0|ensembl:ENSMUSP000000523061600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 20 of 23 rows

Cellular Component
1 to 18 of 18 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Plppr4Ratexternal side of plasma membrane  IDA 1299556 RGD 
Plppr4Ratglutamatergic synapse is_active_inIEAUniProtKB:Q7TME0|ensembl:ENSMUSP000000523061600115GO_REF:0000107EnsemblGO_REF:0000107
Plppr4Ratglutamatergic synapse is_active_inISORGD:16165511624291 PMID:19766573, PMID:27453502RGDPMID:19766573|PMID:27453502
Plppr4Ratmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
Plppr4Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Plppr4Ratplasma membrane is_active_inIBAFB:FBgn0016078|FB:FBgn0041087|MGI:106530|MGI:108412|MGI:1915166|MGI:1923019|PANTHER:PTN000807400|RGD:1303116|RGD:621832|RGD:727806|UniProtKB:O14494|UniProtKB:O14495|UniProtKB:O43688|UniProtKB:P60588|UniProtKB:Q7Z2D51600115GO_REF:0000033GO_CentralGO_REF:0000033
Plppr4Ratplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043
Plppr4Ratpostsynaptic density membrane located_inISORGD:16050991624291 PMID:26671989RGDPMID:26671989
Plppr4Ratpostsynaptic density membrane is_active_inISORGD:16165511624291 PMID:19766573RGDPMID:19766573
Plppr4Ratpostsynaptic density membrane located_inISORGD:16165511624291 PMID:19766573RGDPMID:19766573
Plppr4Ratpostsynaptic density membrane located_inIEAUniProtKB:Q7Z2D5|ensembl:ENSP000003592041600115GO_REF:0000107EnsemblGO_REF:0000107
Plppr4Ratpostsynaptic density membrane located_inIEAUniProtKB:Q7TME0|ensembl:ENSMUSP000000523061600115GO_REF:0000107EnsemblGO_REF:0000107
Plppr4Ratpostsynaptic density membrane located_inIEAUniProtKB-SubCell:SL-05201600115GO_REF:0000044UniProtGO_REF:0000044
Plppr4Ratpostsynaptic density membrane located_inISSUniProtKB:Q7TME01600115GO_REF:0000024UniProtGO_REF:0000024
Plppr4Ratpostsynaptic membrane located_inIEAUniProtKB-KW:KW-06281600115GO_REF:0000043UniProtGO_REF:0000043
Plppr4RatSchaffer collateral - CA1 synapse is_active_inIEAUniProtKB:Q7TME0|ensembl:ENSMUSP000000523061600115GO_REF:0000107EnsemblGO_REF:0000107
Plppr4RatSchaffer collateral - CA1 synapse is_active_inISORGD:16165511624291 PMID:27453502RGDPMID:27453502
Plppr4Ratsynapse located_inIEAUniProtKB-KW:KW-07701600115GO_REF:0000043UniProtGO_REF:0000043
1 to 18 of 18 rows

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Plppr4Ratlipid phosphatase activity  IDA 1299556 RGD 
Plppr4Ratlysophosphatidic acid phosphatase activity enablesIMP 1299556PMID:12730698UniProt 
Plppr4Ratlysophosphatidic acid phosphatase activity NOT|enablesISSUniProtKB:Q7Z2D51600115GO_REF:0000024UniProtGO_REF:0000024
Plppr4Ratlysophosphatidic acid phosphatase activity NOT|enablesISORGD:16050991624291 PMID:15280885RGDPMID:15280885
Plppr4Ratphosphatidate phosphatase activity enablesIBAMGI:108412|PANTHER:PTN000017950|RGD:621832|SGD:S000002692|SGD:S000002911|TAIR:locus:2037758|TAIR:locus:2038826|UniProtKB:O14494|UniProtKB:O14495|UniProtKB:O43688|UniProtKB:P60588|UniProtKB:Q5VZY2|UniProtKB:Q8NEB51600115GO_REF:0000033GO_CentralGO_REF:0000033
Plppr4Ratprotein binding enablesISORGD:16165511624291PR:O08795|PR:Q7TME0 PMID:22337885RGDPMID:22337885


#
Reference Title
Reference Citation
1. A new phospholipid phosphatase, PRG-1, is involved in axon growth and regenerative sprouting. Brauer AU, etal., Nat Neurosci 2003 Jun;6(6):572-8.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. NCBI rat LocusLink and RefSeq merged data October 15, 2003 NCBI rat LocusLink and RefSeq merged data October 15, 2003
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:18643870   PMID:19059322   PMID:19766573   PMID:20167268   PMID:21795542   PMID:22871113   PMID:23015549   PMID:24038138   PMID:25931508  



Plppr4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82208,056,206 - 208,097,191 (-)NCBIGRCr8
mRatBN7.22205,371,317 - 205,412,302 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2205,371,322 - 205,412,302 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2213,018,609 - 213,059,602 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02210,933,198 - 210,974,196 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02205,751,648 - 205,792,638 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02220,298,239 - 220,341,863 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2220,298,245 - 220,341,866 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02238,365,252 - 238,405,892 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42213,686,578 - 213,727,831 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12213,649,335 - 213,690,585 (-)NCBI
Celera2197,848,561 - 197,889,304 (-)NCBICelera
Cytogenetic Map2q42NCBI
PLPPR4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38199,262,924 - 99,309,584 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl199,264,292 - 99,309,590 (+)EnsemblGRCh38hg38GRCh38
GRCh37199,730,048 - 99,775,140 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36199,502,488 - 99,547,728 (+)NCBINCBI36Build 36hg18NCBI36
Celera197,983,902 - 98,029,193 (+)NCBICelera
Cytogenetic Map1p21.3-p21.2NCBI
HuRef197,852,810 - 97,898,096 (+)NCBIHuRef
CHM1_1199,846,184 - 99,891,476 (+)NCBICHM1_1
T2T-CHM13v2.0199,111,296 - 99,157,921 (+)NCBIT2T-CHM13v2.0
Plppr4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393117,112,794 - 117,154,525 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3117,112,788 - 117,154,525 (-)EnsemblGRCm39 Ensembl
GRCm383117,319,145 - 117,360,876 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3117,319,139 - 117,360,876 (-)EnsemblGRCm38mm10GRCm38
MGSCv373117,022,063 - 117,063,794 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363117,311,149 - 117,352,880 (-)NCBIMGSCv36mm8
Celera3123,722,032 - 123,763,668 (-)NCBICelera
Cytogenetic Map3G1NCBI
cM Map350.57NCBI
Plppr4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554354,091,165 - 4,114,376 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554354,085,918 - 4,112,207 (+)NCBIChiLan1.0ChiLan1.0
PLPPR4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21127,720,740 - 127,766,341 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11126,875,286 - 126,920,897 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01101,919,714 - 101,965,146 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11100,640,187 - 100,685,483 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1100,640,187 - 100,685,483 (+)Ensemblpanpan1.1panPan2
PLPPR4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1650,553,769 - 50,594,298 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl650,554,949 - 50,594,383 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha653,237,104 - 53,277,408 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0650,906,076 - 50,946,382 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl650,906,113 - 50,946,341 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1650,599,385 - 50,639,586 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0650,578,764 - 50,619,057 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0651,011,414 - 51,051,742 (-)NCBIUU_Cfam_GSD_1.0
Plppr4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405058108,444,124 - 108,485,378 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936537462,583 - 503,874 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936537462,595 - 503,770 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLPPR4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4118,713,994 - 118,752,224 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14118,713,987 - 118,752,499 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24130,278,777 - 130,316,328 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLPPR4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12033,996,027 - 34,042,145 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2033,996,021 - 34,042,004 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603824,010,104 - 24,055,697 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plppr4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248571,907,932 - 1,956,093 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248571,761,972 - 1,955,112 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Plppr4
288 total Variants

Predicted Target Of
Summary Value
Count of predictions:776
Count of miRNA genes:304
Interacting mature miRNAs:402
Transcripts:ENSRNOT00000022625
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 50 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168358098223265385Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)218960362228801039Rat
152025245Scl81Serum cholesterol level QTL 813.49blood cholesterol amount (VT:0000180)2122609194206936711Rat
61458Bp10Blood pressure QTL 103.42arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189020722215287351Rat
70162Bp63Blood pressure QTL 635.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2114837675212549332Rat

1 to 10 of 50 rows
AW526088  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22205,371,352 - 205,371,561 (-)MAPPERmRatBN7.2
Rnor_6.02220,341,619 - 220,341,827NCBIRnor6.0
Rnor_5.02238,405,648 - 238,405,856UniSTSRnor5.0
RGSC_v3.42213,686,613 - 213,686,821UniSTSRGSC3.4
Celera2197,848,597 - 197,848,805UniSTS
RH 3.4 Map21489.3UniSTS
Cytogenetic Map2q41UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 8 45 107 75 74 43 25 43 6 192 87 87 45 60 31



Ensembl Acc Id: ENSRNOT00000022625   ⟹   ENSRNOP00000022625
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2205,371,322 - 205,412,302 (-)Ensembl
Rnor_6.0 Ensembl2220,298,245 - 220,341,866 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114094   ⟹   ENSRNOP00000084199
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2205,371,322 - 205,390,852 (-)Ensembl
RefSeq Acc Id: NM_001001508   ⟹   NP_001001508
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82208,056,206 - 208,097,191 (-)NCBI
mRatBN7.22205,371,317 - 205,412,302 (-)NCBI
Rnor_6.02220,298,239 - 220,341,863 (+)NCBI
Rnor_5.02238,365,252 - 238,405,892 (+)NCBI
RGSC_v3.42213,686,578 - 213,727,831 (-)RGD
Celera2197,848,561 - 197,889,304 (-)NCBI
Sequence:
Protein RefSeqs NP_001001508 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAP41101 (Get FASTA)   NCBI Sequence Viewer  
  AAP57769 (Get FASTA)   NCBI Sequence Viewer  
  EDL82053 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000022625
GenBank Protein Q7TMB7 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001001508   ⟸   NM_001001508
- UniProtKB: Q7TMB7 (UniProtKB/Swiss-Prot),   G3V864 (UniProtKB/TrEMBL),   A6HVB7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000022625   ⟸   ENSRNOT00000022625
Ensembl Acc Id: ENSRNOP00000084199   ⟸   ENSRNOT00000114094
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TMB7-F1-model_v2 AlphaFold Q7TMB7 1-766 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 19 of 19 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-51476 BioCyc
Ensembl Genes ENSRNOG00000016872 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000022625 ENTREZGENE
Gene3D-CATH Phosphatidic acid phosphatase type 2/haloperoxidase UniProtKB/Swiss-Prot
InterPro P_Acid_Pase_2/haloperoxi_sf UniProtKB/Swiss-Prot
  P_Acid_Pase_2/haloperoxidase UniProtKB/Swiss-Prot
  PLPP UniProtKB/Swiss-Prot
NCBI Gene 295401 ENTREZGENE
PANTHER PTHR10165 UniProtKB/Swiss-Prot
  PTHR10165:SF13 UniProtKB/Swiss-Prot
Pfam PAP2 UniProtKB/Swiss-Prot
PhenoGen Plppr4 PhenoGen
RatGTEx ENSRNOG00000016872 RatGTEx
SMART acidPPc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48317 UniProtKB/Swiss-Prot
UniProt A0A8I6A0S8_RAT UniProtKB/TrEMBL
  A6HVB7 ENTREZGENE, UniProtKB/TrEMBL
  G3V864 ENTREZGENE, UniProtKB/TrEMBL
  PLPR4_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 19 of 19 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-10-26 Plppr4  phospholipid phosphatase related 4  Lppr4  lipid phosphate phosphatase-related protein type 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-11-02 Lppr4  lipid phosphate phosphatase-related protein type 4  Lppr4  plasticity related gene 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-14 Lppr4  plasticity related gene 1  Prg-1  plasticity-related gene 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-07-23 Prg-1  plasticity-related gene 1  Lppr4  plasticity related gene 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Lppr4  plasticity related gene 1  Prg1  plasticity related gene 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-09-30 Prg1        Symbol and Name status set to provisional 70820 PROVISIONAL

Note Type Note Reference
gene_cellular_localization localizes to the plasma membranes of outgrowing axons 1299556
gene_process attenuates phospholipid-induced axon collapse in neurons thereby facilitating axonal outgrowth in the hippocampus 1299556
gene_process acts as an ectoenzyme 1299556