Rgs19 (regulator of G-protein signaling 19) - Rat Genome Database

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Gene: Rgs19 (regulator of G-protein signaling 19) Rattus norvegicus
Analyze
Symbol: Rgs19
Name: regulator of G-protein signaling 19
RGD ID: 629471
Description: Enables G-protein alpha-subunit binding activity. Involved in response to ethanol. Located in brush border and clathrin-coated vesicle. Orthologous to human RGS19 (regulator of G protein signaling 19); INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: calcium/calmodulin-dependent protein kinase I; Camki; G alpha interacting protein; G-alpha-interacting protein; Gaip; MGC108699; regulator of G-protein signalling 19
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Bp286
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83189,182,041 - 189,190,494 (-)NCBIGRCr8
mRatBN7.23168,804,532 - 168,813,035 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3168,804,874 - 168,810,097 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3173,184,366 - 173,189,195 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03182,143,457 - 182,148,286 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03178,805,881 - 178,810,720 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03177,196,276 - 177,204,767 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3177,196,687 - 177,201,525 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03180,904,807 - 180,913,346 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43170,839,907 - 170,844,746 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13170,745,942 - 170,750,782 (-)NCBI
Celera3163,777,979 - 163,782,818 (+)NCBICelera
Cytogenetic Map3q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1,3,5-trinitro-1,3,5-triazinane  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-bromohexadecanoic acid  (ISO)
2-methylcholine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
Allylamine  (EXP)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
chloroprene  (ISO)
choline  (ISO)
cisplatin  (ISO)
clofibric acid  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
cyclosporin A  (ISO)
dextran sulfate  (ISO)
diazinon  (ISO)
dibutyl phthalate  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
flavonoids  (EXP)
flusilazole  (ISO)
folic acid  (ISO)
gentamycin  (EXP)
hexaconazole  (ISO)
ketamine  (EXP)
L-methionine  (ISO)
lead diacetate  (ISO)
lipopolysaccharide  (ISO)
nickel atom  (ISO)
paracetamol  (EXP)
perfluorohexanesulfonic acid  (ISO)
pirinixic acid  (ISO)
quercetin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
Soman  (EXP)
sunitinib  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
triadimefon  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)
zinc atom  (EXP)
zinc sulfate  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. RGS-GAIP, a GTPase-activating protein for Galphai heterotrimeric G proteins, is located on clathrin-coated vesicles. De Vries L, etal., Mol Biol Cell 1998 May;9(5):1123-34.
2. GIPC, a PDZ domain containing protein, interacts specifically with the C terminus of RGS-GAIP. De Vries L, etal., Proc Natl Acad Sci U S A 1998 Oct 13;95(21):12340-5.
3. GAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of G alpha i subunits. De Vries L, etal., Proc Natl Acad Sci U S A. 1996 Dec 24;93(26):15203-8.
4. GAIP, GIPC and Galphai3 are concentrated in endocytic compartments of proximal tubule cells: putative role in regulating megalin's function. Lou X, etal., J Am Soc Nephrol. 2002 Apr;13(4):918-27.
5. Chronic intermittent ethanol exposure selectively alters the expression of Ga subunit isoforms and RGS subtypes in rat prefrontal cortex. Luessen DJ, etal., Brain Res. 2017 Oct 1;1672:106-112. doi: 10.1016/j.brainres.2017.07.014. Epub 2017 Jul 21.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
11. FcgammaRI ligation leads to a complex with BLT1 in lipid rafts that enhances rat lung macrophage antimicrobial functions. Serezani CH, etal., Blood. 2009 Oct 8;114(15):3316-24. doi: 10.1182/blood-2009-01-199919. Epub 2009 Aug 5.
Additional References at PubMed
PMID:10760275   PMID:12477932   PMID:15489334  


Genomics

Comparative Map Data
Rgs19
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83189,182,041 - 189,190,494 (-)NCBIGRCr8
mRatBN7.23168,804,532 - 168,813,035 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3168,804,874 - 168,810,097 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3173,184,366 - 173,189,195 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03182,143,457 - 182,148,286 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03178,805,881 - 178,810,720 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03177,196,276 - 177,204,767 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3177,196,687 - 177,201,525 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03180,904,807 - 180,913,346 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43170,839,907 - 170,844,746 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13170,745,942 - 170,750,782 (-)NCBI
Celera3163,777,979 - 163,782,818 (+)NCBICelera
Cytogenetic Map3q43NCBI
RGS19
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382064,073,181 - 64,079,964 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2064,073,181 - 64,079,988 (-)EnsemblGRCh38hg38GRCh38
GRCh372062,704,534 - 62,711,317 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362062,174,978 - 62,181,768 (-)NCBINCBI36Build 36hg18NCBI36
Build 342062,174,980 - 62,181,309NCBI
Celera2059,390,619 - 59,397,513 (-)NCBICelera
Cytogenetic Map20q13.33NCBI
HuRef2059,438,299 - 59,444,668 (-)NCBIHuRef
CHM1_12062,605,550 - 62,612,340 (-)NCBICHM1_1
T2T-CHM13v2.02065,893,259 - 65,900,019 (-)NCBIT2T-CHM13v2.0
Rgs19
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392181,330,212 - 181,336,330 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2181,330,212 - 181,335,770 (-)EnsemblGRCm39 Ensembl
GRCm382181,688,419 - 181,694,537 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2181,688,419 - 181,693,977 (-)EnsemblGRCm38mm10GRCm38
MGSCv372181,423,128 - 181,428,629 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362181,617,829 - 181,623,330 (-)NCBIMGSCv36mm8
Celera2185,770,805 - 185,776,249 (-)NCBICelera
Cytogenetic Map2H4NCBI
cM Map2103.72NCBI
Rgs19
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955528183,066 - 185,703 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955528183,067 - 185,703 (+)NCBIChiLan1.0ChiLan1.0
RGS19
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22169,891,049 - 69,897,800 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12069,883,060 - 69,889,794 (-)NCBINHGRI_mPanPan1
PanPan1.12061,987,428 - 61,993,936 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2061,987,428 - 61,993,936 (-)Ensemblpanpan1.1panPan2
RGS19
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12447,512,987 - 47,518,282 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2447,512,552 - 47,519,247 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2446,646,828 - 46,652,108 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02448,651,886 - 48,657,163 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2448,651,451 - 48,654,348 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12447,496,513 - 47,501,791 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02447,620,957 - 47,626,215 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02448,359,943 - 48,365,223 (-)NCBIUU_Cfam_GSD_1.0
Rgs19
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640195,797,576 - 195,802,860 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651411,251,202 - 11,255,994 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651411,251,293 - 11,256,461 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RGS19
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1762,889,210 - 62,895,556 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11762,889,207 - 62,896,149 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RGS19
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12166,690 - 173,324 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2169,758 - 173,409 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605047,599,855 - 47,606,545 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rgs19
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474129,700,045 - 29,705,206 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474129,700,033 - 29,705,297 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rgs19
15 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:141
Count of miRNA genes:96
Interacting mature miRNAs:112
Transcripts:ENSRNOT00000022451
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3131635904169034231Rat
1300161Rf10Renal function QTL 103.57renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)3161192952169034231Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3145956084169034231Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141074471169034231Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3130656562169034231Rat
2317883Alcrsp26Alcohol response QTL 261.80.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)3145526770169034231Rat
8552952Pigfal13Plasma insulin-like growth factor 1 level QTL 13blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)3138799500169034231Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3124122556169034231Rat
2298477Eau4Experimental allergic uveoretinitis QTL 40.0011uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)3137398739169034231Rat

Markers in Region
Rgs19  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23168,805,439 - 168,805,586 (+)MAPPERmRatBN7.2
Rnor_6.03177,197,187 - 177,197,333NCBIRnor6.0
Rnor_5.03180,905,718 - 180,905,864UniSTSRnor5.0
RGSC_v3.43170,840,408 - 170,840,554UniSTSRGSC3.4
Celera3163,782,171 - 163,782,317UniSTS
Cytogenetic Map3q43UniSTS
RH132176  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23168,804,592 - 168,804,810 (+)MAPPERmRatBN7.2
Rnor_6.03177,196,340 - 177,196,557NCBIRnor6.0
Rnor_5.03180,904,871 - 180,905,088UniSTSRnor5.0
RGSC_v3.43170,839,561 - 170,839,778UniSTSRGSC3.4
Celera3163,782,947 - 163,783,164UniSTS
RH 3.4 Map31554.7UniSTS
Cytogenetic Map3q43UniSTS
UniSTS:239149  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23168,804,855 - 168,805,333 (+)MAPPERmRatBN7.2
Rnor_6.03177,196,603 - 177,197,080NCBIRnor6.0
Rnor_5.03180,905,134 - 180,905,611UniSTSRnor5.0
RGSC_v3.43170,839,824 - 170,840,301UniSTSRGSC3.4
Celera3163,782,424 - 163,782,901UniSTS
Cytogenetic Map3q43UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000022451   ⟹   ENSRNOP00000022451
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3168,804,950 - 168,810,097 (-)Ensembl
Rnor_6.0 Ensembl3177,196,687 - 177,201,525 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000113622   ⟹   ENSRNOP00000086203
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3168,804,874 - 168,810,097 (-)Ensembl
RefSeq Acc Id: NM_021661   ⟹   NP_067693
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83189,182,448 - 189,187,287 (-)NCBI
mRatBN7.23168,804,939 - 168,809,778 (-)NCBI
Rnor_6.03177,196,686 - 177,201,525 (-)NCBI
Rnor_5.03180,904,807 - 180,913,346 (-)NCBI
RGSC_v3.43170,839,907 - 170,844,746 (-)RGD
Celera3163,777,979 - 163,782,818 (+)RGD
Sequence:
RefSeq Acc Id: XM_006235801   ⟹   XP_006235863
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83189,182,041 - 189,188,028 (-)NCBI
mRatBN7.23168,804,532 - 168,810,221 (-)NCBI
Rnor_6.03177,196,276 - 177,202,000 (-)NCBI
Rnor_5.03180,904,807 - 180,913,346 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008762540   ⟹   XP_008760762
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83189,182,041 - 189,187,657 (-)NCBI
mRatBN7.23168,804,532 - 168,810,189 (-)NCBI
Rnor_6.03177,196,276 - 177,201,908 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008762541   ⟹   XP_008760763
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83189,182,041 - 189,187,737 (-)NCBI
mRatBN7.23168,804,532 - 168,810,219 (-)NCBI
Rnor_6.03177,196,276 - 177,201,919 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063284433   ⟹   XP_063140503
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83189,183,236 - 189,190,494 (-)NCBI
RefSeq Acc Id: XM_063284434   ⟹   XP_063140504
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83189,182,041 - 189,190,469 (-)NCBI
RefSeq Acc Id: NP_067693   ⟸   NM_021661
- UniProtKB: O70521 (UniProtKB/Swiss-Prot),   A6KLX5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006235863   ⟸   XM_006235801
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008760762   ⟸   XM_008762540
- Peptide Label: isoform X4
- UniProtKB: A6KLX9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008760763   ⟸   XM_008762541
- Peptide Label: isoform X4
- UniProtKB: A6KLX9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000022451   ⟸   ENSRNOT00000022451
Ensembl Acc Id: ENSRNOP00000086203   ⟸   ENSRNOT00000113622
RefSeq Acc Id: XP_063140504   ⟸   XM_063284434
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063140503   ⟸   XM_063284433
- Peptide Label: isoform X2
Protein Domains
RGS

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O70521-F1-model_v2 AlphaFold O70521 1-216 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692765
Promoter ID:EPDNEW_R3288
Type:single initiation site
Name:Rgs19_1
Description:regulator of G-protein signaling 19
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03177,201,518 - 177,201,578EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:629471 AgrOrtholog
BioCyc Gene G2FUF-46262 BioCyc
Ensembl Genes ENSRNOG00000016547 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055001222 UniProtKB/Swiss-Prot
  ENSRNOG00060001420 UniProtKB/Swiss-Prot
  ENSRNOG00065014006 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000022451.5 UniProtKB/Swiss-Prot
  ENSRNOT00000113622.1 UniProtKB/TrEMBL
  ENSRNOT00055002045 UniProtKB/Swiss-Prot
  ENSRNOT00060002087 UniProtKB/Swiss-Prot
  ENSRNOT00065023124 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.167.10 UniProtKB/Swiss-Prot
  1.10.196.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Regulator of G-protein Signalling 4, domain 2 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7377022 IMAGE-MGC_LOAD
InterPro RGS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS_subdom1/3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS_subdomain_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:59293 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:108699 IMAGE-MGC_LOAD
NCBI Gene 59293 ENTREZGENE
PANTHER REGULATOR OF G PROTEIN SIGNALING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  REGULATOR OF G-PROTEIN SIGNALING 19 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RGS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rgs19 PhenoGen
PRINTS RGSPROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE RGS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016547 RatGTEx
  ENSRNOG00055001222 RatGTEx
  ENSRNOG00060001420 RatGTEx
  ENSRNOG00065014006 RatGTEx
SMART RGS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Regulator of G-protein signaling, RGS UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt A0A8I6A5E3_RAT UniProtKB/TrEMBL
  A6KLX5 ENTREZGENE, UniProtKB/TrEMBL
  A6KLX7_RAT UniProtKB/TrEMBL
  A6KLX9 ENTREZGENE, UniProtKB/TrEMBL
  A6KLY0_RAT UniProtKB/TrEMBL
  A6KLY1_RAT UniProtKB/TrEMBL
  A6KLY2_RAT UniProtKB/TrEMBL
  O70521 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-01-20 Rgs19  regulator of G-protein signaling 19    calcium/calmodulin-dependent protein kinase I  Name updated 1299863 APPROVED
2003-04-06 Rgs19  calcium/calmodulin-dependent protein kinase I      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to clathrin coated vesicles associated with both the Golgi apparatus and plasma membrane 737647