B3gnt7 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: B3gnt7 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7) Rattus norvegicus
Analyze
Symbol: B3gnt7
Name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
RGD ID: 1310580
Description: Predicted to enable acetylglucosaminyltransferase activity. Predicted to be involved in keratan sulfate biosynthetic process; poly-N-acetyllactosamine biosynthetic process; and protein O-linked glycosylation. Predicted to be active in Golgi membrane. Orthologous to human B3GNT7 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7); PARTICIPATES IN keratan sulfate biosynthetic pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: beta-1,3-Gn-T7; beta-1,3-N-acetylglucosaminyltransferase 7; beta-1,3-N-acetylglucosaminyltransferase-7; beta3Gn-T7; BGnT-7; LOC316583; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8994,404,197 - 94,408,148 (+)NCBIGRCr8
mRatBN7.2986,956,220 - 86,960,171 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl986,956,220 - 86,960,170 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx995,373,838 - 95,377,789 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09100,502,605 - 100,506,556 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0998,884,564 - 98,888,515 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0993,326,283 - 93,330,234 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl993,326,283 - 93,330,233 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0993,055,878 - 93,059,829 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4985,069,241 - 85,073,192NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1985,252,659 - 85,256,610NCBI
Cytogenetic Map9q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:12477932   PMID:15489334  


Genomics

Comparative Map Data
B3gnt7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8994,404,197 - 94,408,148 (+)NCBIGRCr8
mRatBN7.2986,956,220 - 86,960,171 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl986,956,220 - 86,960,170 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx995,373,838 - 95,377,789 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09100,502,605 - 100,506,556 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0998,884,564 - 98,888,515 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0993,326,283 - 93,330,234 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl993,326,283 - 93,330,233 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0993,055,878 - 93,059,829 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4985,069,241 - 85,073,192NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1985,252,659 - 85,256,610NCBI
Cytogenetic Map9q35NCBI
B3GNT7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382231,395,710 - 231,401,164 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2231,395,671 - 231,408,799 (+)EnsemblGRCh38hg38GRCh38
GRCh372232,260,421 - 232,265,875 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362231,968,579 - 231,971,928 (+)NCBINCBI36Build 36hg18NCBI36
Build 342232,085,839 - 232,089,189NCBI
Celera2226,036,697 - 226,042,236 (+)NCBICelera
Cytogenetic Map2q37.1NCBI
HuRef2224,101,622 - 224,107,116 (+)NCBIHuRef
CHM1_12232,266,140 - 232,271,695 (+)NCBICHM1_1
T2T-CHM13v2.02231,880,160 - 231,885,616 (+)NCBIT2T-CHM13v2.0
B3gnt7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39186,230,943 - 86,235,027 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl186,230,554 - 86,235,027 (+)EnsemblGRCm39 Ensembl
GRCm38186,303,221 - 86,307,305 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl186,302,832 - 86,307,305 (+)EnsemblGRCm38mm10GRCm38
MGSCv37188,199,796 - 88,203,880 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36188,134,639 - 88,138,476 (+)NCBIMGSCv36mm8
Celera189,271,394 - 89,275,478 (+)NCBICelera
Cytogenetic Map1C5NCBI
cM Map143.94NCBI
B3gnt7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554534,179,547 - 4,180,737 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554534,178,544 - 4,180,738 (-)NCBIChiLan1.0ChiLan1.0
B3GNT7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213134,015,691 - 134,021,268 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B134,030,664 - 134,036,234 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B118,644,899 - 118,650,463 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
B3GNT7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12543,287,937 - 43,293,416 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2543,847,137 - 43,852,530 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02543,545,318 - 43,550,903 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2543,545,301 - 43,550,890 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12543,472,896 - 43,478,886 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02543,316,106 - 43,321,691 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02543,471,442 - 43,477,003 (+)NCBIUU_Cfam_GSD_1.0
B3gnt7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303185,441,557 - 185,443,920 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365255,496,465 - 5,505,278 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365255,495,815 - 5,508,400 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
B3GNT7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15132,127,396 - 132,131,916 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115132,127,386 - 132,131,912 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215145,843,455 - 145,846,480 (+)NCBISscrofa10.2Sscrofa10.2susScr3
B3GNT7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110117,429,516 - 117,435,910 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604082,013,921 - 82,018,409 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
B3gnt7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248434,603,181 - 4,605,744 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248434,603,014 - 4,606,757 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in B3gnt7
7 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:310
Count of miRNA genes:188
Interacting mature miRNAs:214
Transcripts:ENSRNOT00000024578
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
10058949Gmadr5Adrenal mass QTL 520.014adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)94279151387976209Rat
11353951Bp394Blood pressure QTL 394arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94464992189649921Rat
12879506Pur33Proteinuria QTL 33urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94859825193598251Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)956771635101771635Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)958163035100929646Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)961381434104821652Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)96207227596470995Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)96207227596470995Rat
61385Edpm9Estrogen-dependent pituitary mass QTL 93.430.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)963869687108869687Rat
731171Glom6Glomerulus QTL 62.80.0003kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)964573531109573531Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)975712843111552878Rat
4889852Pur26Proteinuria QTL 26150.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)977813894101597663Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)977813894111552878Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)97927151191616855Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)97927151191616855Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)97927151191616855Rat
724547Cm21Cardiac mass QTL 212.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)979271511102910209Rat
4889943Bss90Bone structure and strength QTL 904.1tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)98636963192058970Rat

Markers in Region
RH137271  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2986,959,960 - 86,960,140 (+)MAPPERmRatBN7.2
Rnor_6.0993,330,024 - 93,330,203NCBIRnor6.0
Rnor_5.0993,059,619 - 93,059,798UniSTSRnor5.0
RGSC_v3.4985,072,982 - 85,073,161UniSTSRGSC3.4
Cytogenetic Map9q35UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 21 24 16 4
Low 1 42 52 36 19 36 2 53 11 25 7
Below cutoff 1 5 5 5 8 9 8

Sequence


RefSeq Acc Id: ENSRNOT00000024578   ⟹   ENSRNOP00000024578
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl986,956,220 - 86,960,170 (+)Ensembl
Rnor_6.0 Ensembl993,326,283 - 93,330,233 (+)Ensembl
RefSeq Acc Id: NM_001012134   ⟹   NP_001012134
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8994,404,197 - 94,408,148 (+)NCBI
mRatBN7.2986,956,220 - 86,960,171 (+)NCBI
Rnor_6.0993,326,283 - 93,330,234 (+)NCBI
Rnor_5.0993,055,878 - 93,059,829 (+)NCBI
RGSC_v3.4985,069,241 - 85,073,192 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001012134 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH81994 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000024578
  ENSRNOP00000024578.4
  ENSRNOP00055010617
  ENSRNOP00060010802
  ENSRNOP00065026297
GenBank Protein Q66H69 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001012134   ⟸   NM_001012134
- UniProtKB: Q66H69 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000024578   ⟸   ENSRNOT00000024578

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q66H69-F1-model_v2 AlphaFold Q66H69 1-397 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696821
Promoter ID:EPDNEW_R7346
Type:multiple initiation site
Name:B3gnt7_1
Description:UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0993,326,492 - 93,326,552EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310580 AgrOrtholog
BioCyc Gene G2FUF-26892 BioCyc
Ensembl Genes ENSRNOG00000018267 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055007880 UniProtKB/Swiss-Prot
  ENSRNOG00060008466 UniProtKB/Swiss-Prot
  ENSRNOG00065019536 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000024578 ENTREZGENE
  ENSRNOT00000024578.6 UniProtKB/Swiss-Prot
  ENSRNOT00055013241 UniProtKB/Swiss-Prot
  ENSRNOT00060014104 UniProtKB/Swiss-Prot
  ENSRNOT00065032903 UniProtKB/Swiss-Prot
Gene3D-CATH 3.90.550.50 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7130315 IMAGE-MGC_LOAD
InterPro Glyco_trans_31 UniProtKB/Swiss-Prot
KEGG Report rno:316583 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94211 IMAGE-MGC_LOAD
NCBI Gene 316583 ENTREZGENE
PANTHER PTHR11214 UniProtKB/Swiss-Prot
  UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 7 UniProtKB/Swiss-Prot
Pfam Galactosyl_T UniProtKB/Swiss-Prot
PhenoGen B3gnt7 PhenoGen
RatGTEx ENSRNOG00000018267 RatGTEx
  ENSRNOG00055007880 RatGTEx
  ENSRNOG00060008466 RatGTEx
  ENSRNOG00065019536 RatGTEx
UniProt B3GN7_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 B3gnt7  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7  LOC100364677  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7-like  Data merged from RGD:2320586 1643240 APPROVED
2010-05-05 LOC100364677  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-12-06 B3gnt7  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7  B3gnt7_predicted  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 B3gnt7_predicted  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 (predicted)      Symbol and Name status set to approved 70820 APPROVED