Wdr46 (WD repeat domain 46) - Rat Genome Database

Name: Wdr46
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Wdr46 (WD repeat domain 46) Rattus norvegicus

Analyze

Symbol:

Wdr46

Name:

WD repeat domain 46

RGD ID:

2209

Description:

Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to localize to nucleolus and small-subunit processome. Orthologous to human WDR46 (WD repeat domain 46); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 4-amino-2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

Bing4; MGC94931; WD repeat-containing protein 46

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	WDR46 (WD repeat domain 46)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Wdr46 (WD repeat domain 46)	HGNC	Treefam, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Wdr46 (WD repeat domain 46)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	WDR46 (WD repeat domain 46)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	WDR46 (WD repeat domain 46)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Wdr46 (WD repeat domain 46)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	WDR46 (WD repeat domain 46)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	WDR46 (WD repeat domain 46)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Wdr46 (WD repeat domain 46)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	WDR46 (WD repeat domain 46)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Mus musculus (house mouse):	Wdr46 (WD repeat domain 46)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Drosophila melanogaster (fruit fly):	CG2260	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Saccharomyces cerevisiae (baker's yeast):	UTP7	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Caenorhabditis elegans (roundworm):	wdr-46	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	20	4,937,845 - 4,945,796 (-)	NCBI
Rnor_6.0 Ensembl	20	5,447,860 - 5,455,632 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	20	5,447,860 - 5,455,632 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	20	7,506,472 - 7,514,244 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	5,089,611 - 5,097,383 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	20	5,089,839 - 5,097,610 (-)	NCBI
Celera	20	6,522,088 - 6,529,834 (-)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal dominant non-syndromic intellectual disability 5 (ISO)

Disease Progression (ISO)

Stomach Neoplasms (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4-amino-2,6-dinitrotoluene (EXP)

ammonium chloride (EXP)

atrazine (ISO)

benzalkonium chloride (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

bisphenol F (ISO)

cadmium atom (ISO)

cadmium dichloride (EXP)

carbon nanotube (ISO)

cisplatin (ISO)

clobetasol (ISO)

clofibric acid (EXP)

cyclosporin A (ISO)

dexamethasone (ISO)

ethyl methanesulfonate (ISO)

flusilazole (ISO)

flutamide (EXP)

folic acid (ISO)

furan (EXP)

hexaconazole (ISO)

hydralazine (ISO)

indometacin (ISO)

methyl methanesulfonate (ISO)

N-nitrosodiethylamine (EXP)

ochratoxin A (EXP)

paracetamol (ISO)

perfluorononanoic acid (ISO)

rac-lactic acid (ISO)

rotenone (EXP)

sodium arsenate (ISO)

tamoxifen (ISO)

testosterone enanthate (ISO)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

triadimefon (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

zinc atom (ISO)

zinc sulfate (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (IBA)

Cellular Component

nucleolus (IBA)

small-subunit processome (IBA)

References

References - curated


1.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Herberg JA, etal., J Mol Biol 1998 Apr 10;277(4):839-57.
3.	MGD data from the GO Consortium
4.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	RGD automated import pipeline for gene-chemical interactions
6.	Walter L and Gunther E, Genomics 1998 Sep 15;52(3):298-304.

Additional References at PubMed

PMID:12477932	PMID:15060004	PMID:22658674	PMID:22681889	PMID:24270810

Genomics

Comparative Map Data

Wdr46
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	20	4,937,845 - 4,945,796 (-)	NCBI
Rnor_6.0 Ensembl	20	5,447,860 - 5,455,632 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	20	5,447,860 - 5,455,632 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	20	7,506,472 - 7,514,244 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	5,089,611 - 5,097,383 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	20	5,089,839 - 5,097,610 (-)	NCBI
Celera	20	6,522,088 - 6,529,834 (-)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

WDR46
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	6	33,279,108 - 33,289,247 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	6	33,278,207 - 33,289,239 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	6	33,246,885 - 33,257,016 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	33,354,863 - 33,364,969 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	6	33,354,863 - 33,364,969	NCBI
Celera	6	34,801,238 - 34,811,662 (-)	NCBI
Cytogenetic Map	6	p21.32	NCBI
HuRef	6	32,988,537 - 32,998,938 (-)	NCBI		HuRef
CHM1_1	6	33,248,816 - 33,259,244 (-)	NCBI		CHM1_1

Wdr46
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	34,159,608 - 34,168,669 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	17	34,159,634 - 34,168,671 (+)	Ensembl
GRCm38	17	33,940,634 - 33,949,695 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	33,940,660 - 33,949,697 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	34,077,668 - 34,086,640 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	17	33,551,177 - 33,560,149 (+)	NCBI			mm8
Celera	17	36,693,635 - 36,702,594 (+)	NCBI		Celera
Cytogenetic Map	17	B1	NCBI

Wdr46
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955437	1,840,791 - 1,848,172 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955437	1,840,875 - 1,848,258 (-)	NCBI	ChiLan1.0	ChiLan1.0

WDR46
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	6	33,965,528 - 33,975,898 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	33,965,528 - 33,975,898 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	6	32,851,335 - 32,861,806 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

WDR46
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	2,721,262 - 2,729,365 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	2,720,658 - 2,729,394 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	2,802,170 - 2,810,395 (-)	NCBI
ROS_Cfam_1.0	12	3,052,429 - 3,060,890 (-)	NCBI
UMICH_Zoey_3.1	12	2,719,901 - 2,728,119 (-)	NCBI
UNSW_CanFamBas_1.0	12	2,801,391 - 2,809,605 (-)	NCBI
UU_Cfam_GSD_1.0	12	2,876,085 - 2,884,317 (-)	NCBI

Wdr46
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	38,373,210 - 38,383,152 (-)	NCBI
SpeTri2.0	NW_004936476	25,577,115 - 25,587,057 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

WDR46
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	29,645,131 - 29,662,400 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	29,645,128 - 29,653,567 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	34,148,893 - 34,157,252 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

WDR46
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	38,787,932 - 38,797,940 (+)	NCBI
ChlSab1.1 Ensembl	17	38,788,275 - 38,799,858 (+)	Ensembl

Wdr46
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624754	23,532,579 - 23,542,109 (+)	NCBI

Position Markers

BE104185

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	20	5,448,116 - 5,448,219	NCBI	Rnor6.0
Rnor_5.0	20	7,506,728 - 7,506,831	UniSTS	Rnor5.0
RGSC_v3.4	20	5,089,867 - 5,089,970	UniSTS	RGSC3.4
Celera	20	6,522,318 - 6,522,421	UniSTS
RH 3.4 Map	20	56.74	UniSTS
Cytogenetic Map	20	p12	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354642	Despr15	Despair related QTL 15		0.0027	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	20	1	24652101	Rat
1600382	Edcs3	Endometrial carcinoma susceptibility QTL3	3.5	0.003	uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	20	1	25653396	Rat
1641893	Alcrsp7	Alcohol response QTL 7			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	26305996	Rat
2317851	Alcrsp22	Alcohol response QTL 22	3.2	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	26305996	Rat
7387283	Uae44	Urinary albumin excretion QTL 44		0.1712	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	20	1	27357423	Rat
9590275	Scort15	Serum corticosterone level QTL 15	3.48	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	28375393	Rat
9589155	Insul32	Insulin level QTL 32	6.38	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	20	1	28375393	Rat
9590109	Sffal8	Serum free fatty acids level QTL 8	5.32	0.01	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	20	1	28375393	Rat
7411650	Foco23	Food consumption QTL 23	20.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	28375393	Rat
8694189	Bw153	Body weight QTL 153	3.13	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	20	1	28375393	Rat
6893685	Bw111	Body weight QTL 111	2.7	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	20	1	33300419	Rat
9590252	Scort12	Serum corticosterone level QTL 12	20.46	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	37550487	Rat
7411668	Foco32	Food consumption QTL 32	8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	37550487	Rat
2305926	Iddm37	Insulin dependent diabetes mellitus QTL 37	6		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	20	2018654	47018654	Rat
2306850	Pia40	Pristane induced arthritis QTL 40		0.0001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	20	2018770	6567419	Rat
1641915	Colcr9	Colorectal carcinoma resistance QTL 9	2.97	0.0024	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	20	2999707	47999707	Rat
61472	Aia1	Adjuvant induced arthritis QTL 1	18	0.001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	20	3151815	6896013	Rat
61448	Ciaa1	CIA Autoantibody QTL 1	30	0.001	blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	20	3151815	6896013	Rat
2317057	Aia27	Adjuvant induced arthritis QTL 27	2.83		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	20	3402111	27968216	Rat
7175096	Tcs1	T cell selection QTL 1			T cell selection	expression	20	3910555	5533640	Rat
61474	Eae1	Experimental allergic encephalomyelitis QTL 1	3		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	20	4039113	5875448	Rat
1558640	Prcs2	Prostate cancer susceptibility QTL 2	3.3		prostate integrity trait (VT:0010571)	percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)	20	4039113	18872273	Rat
4889857	Pur27	Proteinuria QTL 27	12.2	0.001	total urine protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	20	4039113	18872273	Rat
1598816	Memor12	Memory QTL 12	2.4		exploratory behavior trait (VT:0010471)	average horizontal distance in proximity to the target during voluntary locomotion in an experimental apparatus (CMO:0002674)	20	4108956	49108956	Rat
1300152	Bp195	Blood pressure QTL 195	3.46		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	20	4855468	9899946	Rat
1331772	Cdexp2	CD45RC expression in CD8 T cells QTL 2	5.7		CD8-positive T cell quantity (VT:0008077)	blood CD45RChigh CD8 T cell count to CD45RClow CD8 T cell count ratio (CMO:0001990)	20	4855468	10800530	Rat
61432	Cia1	Collagen induced arthritis QTL 1			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	20	4855475	15050565	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	57
Count of miRNA genes:	48
Interacting mature miRNAs:	55
Transcripts:	ENSRNOT00000000552
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	24	40	30	17	30			66	29	41	3
Low		19	17	11	2	11	8	11	8	6		8	8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_212491	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039098678	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC128962	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC085934	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BX883042	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473988	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000324	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000000552 ⟹ ENSRNOP00000000552

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	20	5,447,860 - 5,455,632 (-)	Ensembl

RefSeq Acc Id:

NM_212491 ⟹ NP_997656

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	20	4,937,845 - 4,945,617 (-)	NCBI
Rnor_6.0	20	5,447,860 - 5,455,632 (-)	NCBI
Rnor_5.0	20	7,506,472 - 7,514,244 (-)	NCBI
RGSC_v3.4	20	5,089,611 - 5,097,383 (-)	RGD
Celera	20	6,522,088 - 6,529,834 (-)	RGD

Sequence:

show sequence

TGGGAAGACTGAAAGGAGTTTTGCACGTGGATCGTCGTTCCGTCGTCGGGATGGAGACAGCCCC
CAAGCCGGGTAGGGGTGACCCACCCAAGAAAGACAAGCCTCAGGCCAAGAGGAAGAAACCGCGG
CGCTACTGGGAGGAGGAGCCCACCCCGTCCGCCGCCGGCGCCTCTCCGGGGCCGCCACGGAAGA
AGGCGAGGACTGGGGAGCCGCGACCCCCGAGGTCCCAGAGCGCGCGCATCGCCCAGAAGCCTCG
GTTCTCCAAGAAGCCCCCGATCCCAAAGAACGCCTCAGACTGGAAGAAGCCGCAGAGGACCCTG
TCTGGGGCTCAGGACCCGTTCCCAGGACCTGTCCCCGCCCCCCTGGAGGTGGCCAGGAAGTTCT
GCCGTATTGACAAGTCCAAAAAGCTCCCGCATTCGAAGCCTAAAACCCAAAGCCAACTGGAGAA
GGCTGAAGCACAGGAGGAAGAGGCGAGCGTCAGAGCTGCCCGCGCTGAGCTGCTGCTTGCAGAG
GAACCTGGGTTTCTGGTAGGAGAAGATGGGGAAGACACAGCAAAAATACTGCAGACAGACATCG
TGGAGGCTGTGGACATCTCTAGTGCTGCCAAGCACTTTGACCTGAATCTGAGGCAGTTTGGACC
CTACAGACTGAACTACTCTCGAACTGGGAGACACCTGGCTTTAGGAGGGCGTCGGGGTCACGTG
GCTGCCCTGGATTGGGTGACAAAGAAGCTCATGTGTGAGATCAACGTCACGGAAGCGGTGCGGG
ACATCCACTTTCTCCATTCCGAGGCTCTGCTCGCAGTTGCCCAGAACCGCTGGCTTTACATCTA
CGACAACCAAGGCATCGAGCTCCACTGCATCCGCCGCTGTGACCGAGTGACCCGGCTTGAATTC
CTCCCCTTCCATTTCCTCCTGGCCACCGCTTCAGAGACAGGGTTTCTGACCTACCTGGATGTGT
CAGTGGGGAAGATCGTGACAGCTCTGAATGCGCGGGCTGGACGGCTCAATGTCATGGCTCAGAA
CCCCTACAATGCTGTTATCCACCTCGGACACAGTAATGGCACAGTGTCTTTATGGAGTCCAGCT
ATGAAGGAGCCACTGGCGAAGATTCTGTGTCACCGTGGCGGGGTGCGGGCTGTGGGAGTGGATT
CTACAGGCACGTACATGGCCACCTCTGGTCTGGACCATCAGCTGAAGATCTTTGACTTGCGAGG
GACATTCCAGCCCCTGAGTTCCCGGACCTTACCGCAGGGAGCAGGGCACCTGGCCTTTTCCCAG
CGGGGACTATTAGTTGCGGGAATGGGTGACGTGGTCAACATATGGGCAGGGCAGGGCAAAGGCA
GCCCACCCTCCCTGGAGCAGCCCTACCTCACCCACAGGCTCTCGGGCAATGTGCATGGACTCCA
GTTCTGCCCCTTTGAAGATGTGTTGGGGGTGGGGCACAGTGGAGGCATCACCAGCATGCTGGTC
CCTGGGGCTGCTGAGCCCAACTTTGACGGTTTGGAGAGTAACCCATACCGGAGCCGGAAGCAGC
GCCAGGAGTGGGAGGTGAAGGCCCTGCTGGAGAAGGTACCCGCAGAGCTCATCTGTTTGGACCC
CCGAGCCCTGGCAGAGGTAGATGTGACCACTCTGGAGCAGCAGAAGAAGGAGCGGATAGAGAGG
CTGGGCTACGATCCTGACGCTAAGGCTGCCTTCCAACCCAAGGCAAAGCAGAAGGGCCGAAGCT
CTACAGCGAGCCTGGTGAAGAGGAAGAAGAAGGTCATGGACCAGGAGCACAGGGACAAAGTCCG
GCAGAGCCTTGAGCAACAGCAGAAGAAGAAGCAAGATAAGGCCAAGCCTGGAGCCCATCCATCT
GCACTGGACAGATTTGTACGATGAGCCAGAGACAGCAGTTTCCACCCTGACCCTTAGGGGCCAG
AATGCTCAGTGGGCAAGGCTAAACCTGATGCCAAACCTGAGTTCAGTTCCCAGAAGACACATGG
CAGGAGAAACACACAAGTTGTCTTTTAACCTTTCCGTGCCCACATGGACCAGCACACTTGAGCT
TGTGTGCACGCGTGCGTGCGTGCGTGCGTGCGCGCGCGCGCGCGCGCGCACACACACACACACA
CACACACACACACACACACACACACACACACTGTGAATAACACAGAGATCCATAGGGAAATTGT
CCTGTTTGCCTTGTGTCACAGCTGTGTGAGCCGCTAGCTCCTGGAGGGGAGTGGGCATTAAACA
AGGTTTCTGAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039098678 ⟹ XP_038954606

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	20	4,939,220 - 4,945,796 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_997656	(Get FASTA)	NCBI Sequence Viewer
	XP_038954606	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH85934	(Get FASTA)	NCBI Sequence Viewer
	CAE83923	(Get FASTA)	NCBI Sequence Viewer
	EDL96845	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_997656 ⟸ NM_212491

- UniProtKB:

Q6MGC3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

METAPKPGRGDPPKKDKPQAKRKKPRRYWEEEPTPSAAGASPGPPRKKARTGEPRPPRSQSARI
AQKPRFSKKPPIPKNASDWKKPQRTLSGAQDPFPGPVPAPLEVARKFCRIDKSKKLPHSKPKTQ
SQLEKAEAQEEEASVRAARAELLLAEEPGFLVGEDGEDTAKILQTDIVEAVDISSAAKHFDLNL
RQFGPYRLNYSRTGRHLALGGRRGHVAALDWVTKKLMCEINVTEAVRDIHFLHSEALLAVAQNR
WLYIYDNQGIELHCIRRCDRVTRLEFLPFHFLLATASETGFLTYLDVSVGKIVTALNARAGRLN
VMAQNPYNAVIHLGHSNGTVSLWSPAMKEPLAKILCHRGGVRAVGVDSTGTYMATSGLDHQLKI
FDLRGTFQPLSSRTLPQGAGHLAFSQRGLLVAGMGDVVNIWAGQGKGSPPSLEQPYLTHRLSGN
VHGLQFCPFEDVLGVGHSGGITSMLVPGAAEPNFDGLESNPYRSRKQRQEWEVKALLEKVPAEL
ICLDPRALAEVDVTTLEQQKKERIERLGYDPDAKAAFQPKAKQKGRSSTASLVKRKKKVMDQEH
RDKVRQSLEQQQKKKQDKAKPGAHPSALDRFVR

hide sequence

RefSeq Acc Id:

ENSRNOP00000000552 ⟸ ENSRNOT00000000552

RefSeq Acc Id:	XP_038954606 ⟸ XM_039098678
- Peptide Label:	isoform X1

Protein Domains

WD_REPEATS_REGION

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701412

Promoter ID:

EPDNEW_R11935

Type:

initiation region

Name:

Wdr46_1

Description:

WD repeat domain 46

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	20	5,455,649 - 5,455,709	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:2209	AgrOrtholog
Ensembl Genes	ENSRNOG00000031171	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000000552	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000000552	ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH	2.130.10.10	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7112671	IMAGE-MGC_LOAD
InterPro	BING4_C	UniProtKB/TrEMBL
	WD40/YVTN_repeat-like_dom	UniProtKB/TrEMBL
	WD40_repeat	UniProtKB/TrEMBL
	WD40_repeat_dom	UniProtKB/TrEMBL
	WD40_repeat_dom_sf	UniProtKB/TrEMBL
	WDR46/Utp7	UniProtKB/TrEMBL
KEGG Report	rno:309628	UniProtKB/TrEMBL
MGC_CLONE	MGC:94931	IMAGE-MGC_LOAD
NCBI Gene	309628	ENTREZGENE
PANTHER	PTHR14085	UniProtKB/TrEMBL
Pfam	BING4CT	UniProtKB/TrEMBL
PhenoGen	Wdr46	PhenoGen
PROSITE	WD_REPEATS_REGION	UniProtKB/TrEMBL
SMART	BING4CT	UniProtKB/TrEMBL
	WD40	UniProtKB/TrEMBL
Superfamily-SCOP	WD40_like	UniProtKB/TrEMBL
UniProt	Q6MGC3	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	F7EQJ9	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-07-20	Wdr46	WD repeat domain 46	Bing4	Unknown function	Symbol and Name updated to reflect Human and Mouse nomenclature	1299863	APPROVED
2002-06-10	Bing4	Unknown function			Symbol and Name status set to approved	70586	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

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