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Gene: Kdm8 (lysine demethylase 8) Rattus norvegicus
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Symbol: Kdm8
Name: lysine demethylase 8
Description: Predicted to have several functions, including histone demethylase activity (H3-K36 specific); methylated histone binding activity; and peptidase activity. Predicted to be involved in several processes, including histone H3-K36 demethylation; protein destabilization; and regulation of gene expression. Predicted to localize to the cytosol and nucleoplasm. Orthologous to human KDM8 (lysine demethylase 8); PARTICIPATES IN histone modification pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; chlorpyrifos.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: arginyl C3-hydroxylase KDM8; bifunctional peptidase and arginyl-hydroxylase JMJD5; jmjC domain-containing protein 5; Jmjd5; jumonji C domain-containing protein 5; jumonji domain containing 5; jumonji domain-containing protein 5; L-arginine (3R)-hydroxylase KDM8; LOC308976; lysine (K)-specific demethylase 8; lysine-specific demethylase 8; MGC124735; RGD1304823; similar to RIKEN cDNA 3110005O21
Orthologs:
Homo sapiens (human) : KDM8 (lysine demethylase 8)  HGNC  Alliance
Mus musculus (house mouse) : Kdm8 (lysine (K)-specific demethylase 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm8 (lysine demethylase 8)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM8 (lysine demethylase 8)
Canis lupus familiaris (dog) : KDM8 (lysine demethylase 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm8 (lysine demethylase 8)
Sus scrofa (pig) : KDM8 (lysine demethylase 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01196,838,460 - 196,854,192 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01203,825,823 - 203,840,790 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41184,510,173 - 184,525,036 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11184,666,742 - 184,674,917 (+)NCBI
Celera1177,684,363 - 177,699,127 (+)NCBICelera
Cytogenetic Map1q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Kdm8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1304823
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.