Eef2k (eukaryotic elongation factor-2 kinase)

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Gene: Eef2k (eukaryotic elongation factor-2 kinase) Rattus norvegicus

Analyze

Symbol:

Eef2k

Name:

eukaryotic elongation factor-2 kinase

RGD ID:

2538

Description:

Enables elongation factor-2 kinase activity. Involved in several processes, including cellular response to anoxia; positive regulation of cellular component organization; and response to peptide hormone. Located in dendritic spine. Is active in glutamatergic synapse and postsynaptic density. Orthologous to human EEF2K (eukaryotic elongation factor 2 kinase); PARTICIPATES IN mTOR signaling pathway; INTERACTS WITH (+)-schisandrin B; 1,2,4-trimethylbenzene; 17alpha-ethynylestradiol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase; eEF-2 kinase; eEF-2K; elongation factor 2 kinase; eukaroytic elongation factor 2 kinase; Eukaryotic elongation factor 2 kinase; SMEF2K

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	EEF2K (eukaryotic elongation factor 2 kinase)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Eef2k (eukaryotic elongation factor-2 kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Eef2k (eukaryotic elongation factor 2 kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	EEF2K (eukaryotic elongation factor 2 kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	EEF2K (eukaryotic elongation factor 2 kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Eef2k (eukaryotic elongation factor 2 kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	EEF2K (eukaryotic elongation factor 2 kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	EEF2K (eukaryotic elongation factor 2 kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Eef2k (eukaryotic elongation factor 2 kinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Eef2k (eukaryotic elongation factor-2 kinase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	EEF2K (eukaryotic elongation factor 2 kinase)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	eef2k (eukaryotic elongation factor 2 kinase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	efk-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	eef2k	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	175,393,119 - 175,456,756 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	175,393,154 - 175,455,164 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	183,753,768 - 183,794,993 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	190,939,743 - 190,980,965 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	183,625,310 - 183,666,539 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	190,780,211 - 190,839,926 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	190,780,236 - 190,842,324 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	197,704,669 - 197,766,058 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	179,712,404 - 179,754,345 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	179,832,738 - 179,895,924 (+)	NCBI
Celera	1	173,143,531 - 173,184,040 (+)	NCBI		Celera
Cytogenetic Map	1	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alzheimer's disease (ISO)

autistic disorder (ISO)

genetic disease (ISO)

lung adenocarcinoma (ISO)

schizophrenia (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(-)-epigallocatechin 3-gallate (ISO)

1,2,4-trimethylbenzene (EXP)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP,ISO)

17beta-estradiol (EXP,ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,2',5,5'-tetrachlorobiphenyl (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-amino-2,6-dinitrotoluene (EXP)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

aldehydo-D-glucose (ISO)

amitrole (EXP)

ammonium chloride (EXP)

arsane (ISO)

arsenic atom (ISO)

azoxystrobin (ISO)

Benoxacor (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP)

C60 fullerene (EXP)

caffeine (ISO)

cantharidin (ISO)

carbamazepine (ISO)

chloroprene (EXP)

choline (ISO)

cisplatin (ISO)

copper atom (ISO)

copper(0) (ISO)

corticosterone (EXP)

Cuprizon (EXP)

cyclosporin A (ISO)

D-glucose (ISO)

decabromodiphenyl ether (EXP)

diazinon (ISO)

diclofenac (ISO)

dicrotophos (ISO)

diethyl maleate (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

ethyl methanesulfonate (ISO)

fenvalerate (EXP)

flavonoids (EXP)

folic acid (ISO)

formaldehyde (ISO)

glucose (ISO)

glycine betaine (EXP)

hydroquinone (ISO)

iron atom (EXP)

iron(0) (EXP)

ketamine (EXP)

L-methionine (ISO)

lead(0) (ISO)

leflunomide (ISO)

methamphetamine (ISO)

methapyrilene (ISO)

methimazole (EXP)

methyl methanesulfonate (ISO)

N-methyl-4-phenylpyridinium (EXP)

paracetamol (EXP,ISO)

paraquat (ISO)

PCB138 (EXP,ISO)

phenethyl isothiocyanate (EXP)

pirinixic acid (ISO)

potassium chromate (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

progesterone (ISO)

resveratrol (EXP,ISO)

rotenone (EXP,ISO)

SB 431542 (ISO)

Soman (EXP)

sulforaphane (ISO)

tamoxifen (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

titanium dioxide (EXP)

triadimefon (EXP)

tributylstannane (EXP)

trichostatin A (ISO)

triphenyl phosphate (EXP)

triptonide (ISO)

trovafloxacin (ISO)

tungsten (ISO)

undecane (EXP)

valproic acid (ISO)

vinclozolin (EXP)

zinc atom (EXP)

zinc sulfate (EXP)

zinc(0) (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to anoxia (IEP)

cellular response to brain-derived neurotrophic factor stimulus (IEP)

cellular response to calcium ion (IEP)

cellular response to cAMP (IEP)

cellular response to insulin stimulus (IEP)

myosin II filament disassembly (IBA)

negative regulation of apoptotic process (IMP)

positive regulation of dendritic spine morphogenesis (IMP)

positive regulation of endocytosis (IMP)

positive regulation of synapse assembly (IMP)

regulation of protein autophosphorylation (ISO)

regulation of translation at postsynapse (IDA,IEP,IMP)

response to ischemia (IEP)

response to prolactin (IEP)

Cellular Component

dendritic spine (IDA)

glutamatergic synapse (IDA,IEP,IMP)

postsynaptic density (IDA,IEP)

Molecular Function

ATP binding (IEA)

calcium ion binding (IEA)

calmodulin binding (ISO,ISS)

elongation factor-2 kinase activity (IBA,IMP,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

mTOR signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Prolactin regulation of the calmodulin-dependent protein kinase III elongation factor-2 system in the rat corpus luteum.	Albarracin CT, etal., J Biol Chem. 1994 Mar 11;269(10):7772-6.
2.	Localization of translational components at the ultramicroscopic level at postsynaptic sites of the rat brain.	Asaki C, etal., Brain Res. 2003 May 16;972(1-2):168-76.
3.	Characterization of the role of microtubule-associated protein 1B in metabotropic glutamate receptor-mediated endocytosis of AMPA receptors in hippocampus.	Davidkova G and Carroll RC, J Neurosci. 2007 Nov 28;27(48):13273-8.
4.	Regulation of protein-synthesis elongation-factor-2 kinase by cAMP in adipocytes.	Diggle TA, etal., Biochem J. 1998 Dec 15;336 ( Pt 3):525-9.
5.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
7.	Gastric Adenocarcinoma Predictive Long Intergenic Non-Coding RNA Promotes Tumor Occurrence and Progression in Non-Small Cell Lung Cancer via Regulation of the miR-661/eEF2K Signaling Pathway.	Gu H, etal., Cell Physiol Biochem. 2018;51(5):2136-2147. doi: 10.1159/000495831. Epub 2018 Dec 6.
8.	Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis.	Horman S, etal., Curr Biol. 2002 Aug 20;12(16):1419-23.
9.	Myocardial ischemia and increased heart work modulate the phosphorylation state of eukaryotic elongation factor-2.	Horman S, etal., J Biol Chem. 2003 Oct 24;278(43):41970-6. Epub 2003 Aug 14.
10.	KEGG: Kyoto Encyclopedia of Genes and Genomes	KEGG
11.	Levels of mTOR and its downstream targets 4E-BP1, eEF2, and eEF2 kinase in relationships with tau in Alzheimer's disease brain.	Li X, etal., FEBS J. 2005 Aug;272(16):4211-20.
12.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
13.	PID Annotation Import Pipeline	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
14.	Cloning and expression of cDNA encoding protein synthesis elongation factor-2 kinase.	Redpath NT, etal., J Biol Chem 1996 Jul 19;271(29):17547-54.
15.	GOA pipeline	RGD automated data pipeline
16.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
17.	A Ca(2+)-calmodulin-eEF2K-eEF2 signalling cascade, but not AMPK, contributes to the suppression of skeletal muscle protein synthesis during contractions.	Rose AJ, etal., J Physiol. 2009 Apr 1;587(Pt 7):1547-63. doi: 10.1113/jphysiol.2008.167528. Epub 2009 Feb 2.
18.	Identification of a new class of protein kinases represented by eukaryotic elongation factor-2 kinase.	Ryazanov AG, etal., Proc Natl Acad Sci U S A 1997 May 13;94(10):4884-9.
19.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
20.	Brain-derived neurotrophic factor enhances the basal rate of protein synthesis by increasing active eukaryotic elongation factor 2 levels and promoting translation elongation in cortical neurons.	Takei N, etal., J Biol Chem. 2009 Sep 25;284(39):26340-8. doi: 10.1074/jbc.M109.023010. Epub 2009 Jul 22.
21.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
22.	AMP-activated protein kinase protects cardiomyocytes against hypoxic injury through attenuation of endoplasmic reticulum stress.	Terai K, etal., Mol Cell Biol. 2005 Nov;25(21):9554-75.
23.	Synaptic activity controls dendritic spine morphology by modulating eEF2-dependent BDNF synthesis.	Verpelli C, etal., J Neurosci. 2010 Apr 28;30(17):5830-42. doi: 10.1523/JNEUROSCI.0119-10.2010.

Additional References at PubMed

PMID:14709557	PMID:23184662	PMID:23640883	PMID:23812389	PMID:25943107	PMID:27005990	PMID:27317589	PMID:28205128	PMID:30737648	PMID:32569665	PMID:33191388	PMID:35598844

Genomics

Comparative Map Data

Eef2k
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	175,393,119 - 175,456,756 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	175,393,154 - 175,455,164 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	183,753,768 - 183,794,993 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	190,939,743 - 190,980,965 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	183,625,310 - 183,666,539 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	190,780,211 - 190,839,926 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	190,780,236 - 190,842,324 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	197,704,669 - 197,766,058 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	179,712,404 - 179,754,345 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	179,832,738 - 179,895,924 (+)	NCBI
Celera	1	173,143,531 - 173,184,040 (+)	NCBI		Celera
Cytogenetic Map	1	q36	NCBI

EEF2K
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	22,206,278 - 22,288,738 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	22,206,278 - 22,288,738 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	22,217,599 - 22,300,059 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	22,125,093 - 22,207,567 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	22,125,256 - 22,205,452	NCBI
Celera	16	20,997,480 - 21,079,953 (+)	NCBI		Celera
Cytogenetic Map	16	p12.2	NCBI
HuRef	16	20,462,336 - 20,544,660 (+)	NCBI		HuRef
CHM1_1	16	22,091,272 - 22,173,735 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	16	21,928,475 - 22,010,936 (-)	NCBI		T2T-CHM13v2.0

Eef2k
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	120,442,080 - 120,506,441 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	120,442,054 - 120,506,673 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	120,842,642 - 120,907,219 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	120,842,831 - 120,907,450 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	127,986,397 - 128,047,515 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	120,634,032 - 120,695,150 (+)	NCBI		MGSCv36	mm8
Celera	7	120,755,613 - 120,816,599 (+)	NCBI		Celera
Cytogenetic Map	7	F2	NCBI
cM Map	7	64.95	NCBI

Eef2k
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955493	865,830 - 922,765 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955493	865,830 - 922,765 (+)	NCBI	ChiLan1.0	ChiLan1.0

EEF2K
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	16	27,571,678 - 27,654,230 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	16,443,579 - 16,526,061 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	22,518,150 - 22,598,735 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	22,537,518 - 22,596,091 (+)	Ensembl	panpan1.1		panPan2

EEF2K
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	23,368,296 - 23,433,853 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	23,371,546 - 23,433,929 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	24,863,141 - 24,928,560 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	23,506,671 - 23,572,566 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	23,506,218 - 23,572,676 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	23,308,900 - 23,374,695 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	23,218,207 - 23,280,831 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	23,600,299 - 23,665,719 (-)	NCBI		UU_Cfam_GSD_1.0

Eef2k
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	119,053,057 - 119,105,538 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936501	7,160,134 - 7,207,377 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936501	7,160,134 - 7,205,231 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

EEF2K
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	23,887,125 - 23,956,373 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	23,887,120 - 23,980,231 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	24,287,297 - 24,412,626 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

EEF2K
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	19,871,669 - 19,957,471 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	19,871,310 - 19,957,395 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666068	9,911,761 - 9,997,341 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Eef2k
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624782	7,606,655 - 7,666,206 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624782	7,606,576 - 7,668,771 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Eef2k
335 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	550
Count of miRNA genes:	267
Interacting mature miRNAs:	347
Transcripts:	ENSRNOT00000022726
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32737458	199368955	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	49393289	199050459	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	81591954	219808434	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	90508614	180359386	Rat
1331751	Bp199	Blood pressure QTL 199	3.60022		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	94494440	181830018	Rat
1331749	Hrtrt11	Heart rate QTL 11	2.973		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	94494440	198211706	Rat
70209	Niddm23	Non-insulin dependent diabetes mellitus QTL 23	2.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	94494440	198324465	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94642644	214537671	Rat
8655649	Arrd1	Age-related retinal degeneration QTL 1	4.89		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	100357752	183970443	Rat
1354591	Cm36	Cardiac mass QTL 36	4.1		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	102813953	201278233	Rat
1354615	Cm32	Cardiac mass QTL 32	5.2		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	102813953	201278233	Rat
1354606	Bp246	Blood pressure QTL 246	3.6		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	102813953	218753816	Rat
1300158	Bp173	Blood pressure QTL 173	3.48		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	1	115540693	185145286	Rat
7794788	Mcs32	Mammary carcinoma susceptibility QTL 32	2.61		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	1	115540693	238914717	Rat
7421630	Bp362	Blood pressure QTL 362		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	118608292	241799120	Rat
631205	Bp196	Blood pressure QTL 196	4	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	118944897	199050459	Rat
631544	Bp84	Blood pressure QTL 84	5.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	123350408	181759564	Rat
1358189	Cstrr1	Cold stress response QTL 1		0.0001	catecholamine amount (VT:0010543)	urine norepinephrine level (CMO:0001629)	1	123350408	182418476	Rat
1641895	Bp298	Blood pressure QTL 298			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	123350408	182418476	Rat
1578770	Stresp23	Stress response QTL 23			kidney sympathetic nerve activity (VT:0004050)	stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)	1	123350408	182418476	Rat
631549	Bp89	Blood pressure QTL 89	5.7		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	123350581	201284552	Rat
738006	Anxrr14	Anxiety related response QTL 14	4	0.00035	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	130636910	175636910	Rat
738028	Anxrr12	Anxiety related response QTL 12	4.9	0.00001	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	130636910	175636910	Rat
6893347	Bw98	Body weight QTL 98	0.2	0.53	body mass (VT:0001259)	body weight (CMO:0000012)	1	133680936	178680936	Rat
6893361	Bw104	Body weight QTL 104	0.59	0.27	body mass (VT:0001259)	body weight (CMO:0000012)	1	133680936	178680936	Rat
1558645	Bw55	Body weight QTL 55	3.2	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	1	133680936	178680936	Rat
71118	Thym1	Thymus enlargement QTL 1	10.17	0.001	thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	1	136829932	181829932	Rat
724550	Thym3	Thymus enlargement QTL 3	7.82	0.001	thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	1	136829932	181829932	Rat
631519	Pia11	Pristane induced arthritis QTL 11	5.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	136830018	181830018	Rat
1598853	Memor3	Memory QTL 3	4.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	1	143506580	212458660	Rat
61348	Bp30	Blood pressure QTL 30	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	144017057	197814409	Rat
70160	Bw18	Body weight QTL 18	5.7		body mass (VT:0001259)	body weight (CMO:0000012)	1	144267353	196383668	Rat
737828	Hcas3	Hepatocarcinoma susceptibility QTL 3	4.9		liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	1	144267353	222987745	Rat
2302378	Insul11	Insulin level QTL 11	3.25		blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	1	144267353	251128347	Rat
7771612	Cm80	Cardiac mass QTL 80	8.4		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	1	149448574	221264292	Rat
724531	Uae5	Urinary albumin excretion QTL 5	4		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	1	150700142	252085212	Rat
1578759	Uae30	Urinary albumin excretion QTL 30	3.3	0.003	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	150700247	252085048	Rat
1578778	Pur4	Proteinuria QTL 4	3.3	0.003	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	1	150700247	252085048	Rat
1354602	Bw35	Body weight QTL 35	12.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	201278233	Rat
1354620	Kidm19	Kidney mass QTL 19	4		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	151162512	201278233	Rat
1354634	Kidm12	Kidney mass QTL 12	3.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	1	151162512	201278233	Rat
1354636	Lmblg1	Limb length QTL 1	6.4		tibia length (VT:0004357)	tibia length (CMO:0000450)	1	151162512	201278233	Rat
1354610	Bw34	Body weight QTL 34	4.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
1354646	Kidm18	Kidney mass QTL 18	5.7		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	151162512	256448636	Rat
1354661	Bw33	Body weight QTL 33	5.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
1358886	Bp260	Blood pressure QTL 260	3.67		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	151162766	225824951	Rat
61343	Bp28	Blood pressure QTL 28			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	151646613	196646613	Rat
1549837	Hcar15	Hepatocarcinoma resistance QTL 15		0.05	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	153136852	260522016	Rat
2303622	Vencon6	Ventilatory control QTL 6		0.001	respiration trait (VT:0001943)	respiration rate (CMO:0000289)	1	154561505	199561505	Rat
4889428	Stresp24	Stress response QTL 24		0.05	heart pumping trait (VT:2000009)	absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)	1	155866514	200866514	Rat
631548	Bp88	Blood pressure QTL 88	5	0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	156677124	176484451	Rat
1354618	Kidm15	Kidney mass QTL 15	5		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	1	156677124	201278233	Rat
2312420	Pur17	Proteinuria QTL 17	7.1	0.0001	urine protein amount (VT:0005160)	urine total protein excretion rate (CMO:0000756)	1	156677124	218753816	Rat
1354580	Scort1	Serum corticosterone level QTL 1	3.4		blood corticosterone amount (VT:0005345)	blood corticosterone level (CMO:0001172)	1	156677124	256448636	Rat
61347	Bp197	Blood pressure QTL 197	4.2		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	1	158633083	203633083	Rat
2292222	Bp307	Blood pressure QTL 307	3.06	0.0014	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	164310393	213533942	Rat
2292220	Bp306	Blood pressure QTL 306	3.47	0.00087	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	164310393	243914901	Rat
619613	Bp77	Blood pressure QTL 77		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	164747424	209747424	Rat
619613	Bp77	Blood pressure QTL 77		0.01	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	164747424	209747424	Rat
737974	Bp161	Blood pressure QTL 161		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	164747558	181133855	Rat
2312558	Glom17	Glomerulus QTL 17	3.9	0.001	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	1	166532971	191278129	Rat
1354653	Despr9	Despair related QTL 9		0.00019	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	167909849	212909849	Rat
619614	Bp78	Blood pressure QTL 78		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	169112897	197261052	Rat
619614	Bp78	Blood pressure QTL 78		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	169112897	197261052	Rat
61341	Bp26	Blood pressure QTL 26			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	169537671	214537671	Rat
724562	Rends1	Renal damage susceptibility QTL 1		0.05	kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	1	169537671	214537671	Rat
1358294	Bw37	Body weight QTL 37	5	0.000011	body mass (VT:0001259)	body weight (CMO:0000012)	1	171310381	216310381	Rat
2293689	Bss47	Bone structure and strength QTL 47	7.25	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	1	171629477	216629477	Rat
2293693	Bss22	Bone structure and strength QTL 22	33.52	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	1	171629477	216629477	Rat
2300161	Bmd43	Bone mineral density QTL 43	8.4	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	171629477	216629477	Rat
2300174	Bmd42	Bone mineral density QTL 42	8.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	bone mineral density (CMO:0001226)	1	171629477	216629477	Rat
2300187	Bmd41	Bone mineral density QTL 41	8.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	171629477	216629477	Rat
2293654	Bss30	Bone structure and strength QTL 30	32.65	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	1	171629477	216629477	Rat
2293673	Bss27	Bone structure and strength QTL 27	18.63	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	1	171629477	216629477	Rat
2293677	Bss41	Bone structure and strength QTL 41	9.38	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra cross-sectional area (CMO:0001689)	1	171629477	216629477	Rat
1549830	Bss1	Bone structure and strength QTL 1	4.8		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	1	172609619	217609619	Rat
61326	Eae6	Experimental allergic encephalomyelitis QTL 6	5.3		body mass (VT:0001259)	change in body weight (CMO:0002045)	1	172949660	181830018	Rat
631214	Bw61	Body weight QTL61	3.4	0.0001	intramuscular adipose amount (VT:0010044)	intramuscular fat area (CMO:0001162)	1	173108781	218108781	Rat
631670	Iddm10	Insulin dependent diabetes mellitus QTL 10	1.9		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	174133260	196383668	Rat
70163	Bw20	Body weight QTL 20	5.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	174133260	219133260	Rat

Markers in Region

AI102667

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	175,432,817 - 175,432,969 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	190,819,682 - 190,819,833	NCBI	Rnor6.0
Rnor_5.0	1	197,745,820 - 197,745,971	UniSTS	Rnor5.0
RGSC_v3.4	1	179,733,272 - 179,733,423	UniSTS	RGSC3.4
Celera	1	173,164,030 - 173,164,181	UniSTS
Cytogenetic Map	1	q35	UniSTS

RH133994

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	175,439,360 - 175,439,547 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	190,826,223 - 190,826,409	NCBI	Rnor6.0
Rnor_5.0	1	197,752,355 - 197,752,541	UniSTS	Rnor5.0
RGSC_v3.4	1	179,740,875 - 179,741,061	UniSTS	RGSC3.4
Celera	1	173,170,564 - 173,170,750	UniSTS
Cytogenetic Map	1	q35	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	36	31	23	11	23	8	11	66	21	33	11	8
Low		7	26	18	8	18			8	14	8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_012947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006230157	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006230158	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101738	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC116250	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC145398	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC061825	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473956	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000044	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U93849	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X96426	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000022726 ⟹ ENSRNOP00000022726

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	175,393,154 - 175,455,164 (+)	Ensembl
Rnor_6.0 Ensembl	1	190,780,236 - 190,842,324 (+)	Ensembl

RefSeq Acc Id:

NM_012947 ⟹ NP_037079

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	175,393,127 - 175,456,756 (+)	NCBI
Rnor_6.0	1	190,798,705 - 190,839,693 (+)	NCBI
Rnor_5.0	1	197,704,669 - 197,766,058 (+)	NCBI
RGSC_v3.4	1	179,712,404 - 179,754,345 (+)	RGD
Celera	1	173,143,531 - 173,184,040 (+)	RGD

Sequence:

show sequence

ATGGCAGACGAAGACCTCATCTTCCGCCTGGAAGGTGTTGACGGTGGCGGGTCCTCCGGAGCTG
GCCGCCATGGGGACTCTGACACAGACAGTGACGATGATGAGGGCTACTTCATCTGCCCCATCAC
TGATGACCACATGTCCAACCAGAATGTCAACTCCAAAGGCCAGGGCTACTACAACAACCTACTG
AAAACGGAGTGTGGCTCCACAGGGTCACCAGCCAGCTCCTTCCACTTCAAGGAGGCCTGGAAGC
ATGCGATCGAGAAGGCCAAGCACATGCCCGACCCCTGGGCTGAATTCCATCTGGAGGACATCGC
CACAGAGCATGCTACTCGGCACAGGTACAATGCTGTCACCGGGGAGTGGCTGAAAGACGAGGTT
CTGATCAAGATGGCATCTCAGCCCTTCGGCCGTGGAGCAATGAGGGAGTGCTTCAGGACGAAGA
AACTCTCCAACTTCTTGCATGCCCAGCATTGGAAGGGGGCCTCCAACTACGTGGCAAAACGCTA
CCTCGAGCCAGTGGACAGGAGCGTGTACTTTGAGGATGTGCAGCTCCAGATGGAAGCGAAGCTC
TGGGGGGAGGAGTACAACCGGCACAAGCCCCCCAAGCAGGTAGATATCATGCAGATGTGCATCA
TTGAGCTAAAGGACAGACAAGGACAGCCCCTCTTCCACCTGGAGCACTACATTGAGGGCAAGTA
CATCAAGTATAATTCCAACTCAGGCTTTGTCCGTGATGACAACATCAGACTAACACCACAGGCC
TTCAGCCATTTCACATTTGAACGTTCTGGTCATCAGCTGATTGTAGTGGACATCCAGGGTGTGG
GCGACCTTTATACTGACCCACAGATCCACACTGAGAAAGGCACTGACTTTGGAGATGGTAACCT
TGGTGTCCGGGGAATGGCTCTCTTCTTCTACTCTCATGCCTGCAACCGTATTTGCCAGAGCATG
GGCCTTGCGCCCTTTGACCTCTCCCCACGGGAGCAGGATGCCGTGAACCAGAGCACCAAGCTGT
TGCAATCAGCCAAGACCATCTTGAGGGGGACAGAGGAGAAGTGTGGGAGTCCCCGCATAAGGAC
ACTCTCTGGCAGCCGGCCCCCCTTGCTCCTTCGCCTGTCAGAGAACTCTGGGGATGAGAACATG
AGTGATGTGACCTTTGACTCTCTGCCTTCCTCCCCGTCTTCAGCCACACCACACAGCCAGAAGT
TGGACCACCTCCATTGGCCAGTGTTTGGTGACCTCGATAACATGGGCCCTAGAGACCATGACCG
CATGGACAATCACCGGGACTCTGAGAATAGTGGGGACAGTGGGTATCCAAGCGAGAAGCGAAGT
GACCTGGATGATCCTGAGCCCCGAGAACACGGCCACTCCAATGGCAACCGAAGGCCTGAATCTG
ATGAGGACAGCCTGGGCAGCTCTGGACGGGTCTGTGTGGAGACGTGGAACCTGCTCAATCCCTC
CCGCCTGCACCTGCCCAGGCCCTCGGCCGTGGCCCTAGAAGTGCAAAGGTTAAATGCTCTGGAC
CTTGGAAGGAAAATCGGGAAGTCTGTTTTGGGGAAGGTCCATCTGGCCATGGTACGGTACCACG
AGGGCGGGCGCTTCTGCGAGAAGGATGAGGAATGGGATCAAGAGTCTGCCATCTTCCATCTGGA
GCATGCAGCCGACCTGGGAGAACTGGAGGCCATCGTGGGCCTAGGCCTCATGTACTCTCAGCTG
CCCCACCACATCCTGGCTGATGTCTCTCTGGAGGAGACAGAAGAGAACAAGACAAAAGGCTTTG
ATTACCTCCTGAAGGCCGCAGAAGCTGGTGACAGGCAGTCCATGATTTTAGTGGCTCGAGCTTT
TGACACCGGCCTGAACCTCAGCCCAGACAGGTGTCAAGACTGGTCGGAAGCCTTACACTGGTAC
AACACGGCCCTGGAGACGACGGACTGCGATGAAGGCGGGGAGTATGACGGAATACAGGACGAGC
CCCAGTATGCACTGCTGGCCAGGGAGGCAGAGATGTTGCTCACCGGTGGATTTGGACTGGACAA
GAACCCCCAAAGATCAGGAGACTTGTACACCCAGGCAGCCGAGGCAGCAATGGAAGCCATGAAG
GGCCGGCTAGCCAACCAGTACTATGAGAAGGCGGAAGAGGCCTGGGCGCAAATGGAGGAATAA

hide sequence

RefSeq Acc Id:

XM_006230157 ⟹ XP_006230219

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	175,393,824 - 175,454,452 (+)	NCBI
Rnor_6.0	1	190,780,465 - 190,839,926 (+)	NCBI
Rnor_5.0	1	197,704,669 - 197,766,058 (+)	NCBI

Sequence:

show sequence

CGCCTCCAGCTGCAGTGGCCCCCCGAAAGGAGCTTCTTTGGTTGCAGAGCTTCCGCGGGGCTCA
GTATTTGCGCCTATAAAGAAAAGAATGAAAGACGCTGGCAAGCGATGGGCGGGCGCCGTTCGGG
TTGCACCAGGCAGCGCACGCGGGCTTCCGCCAGGGTCTCTCCTTCGTGTCTCGGAGAACCCGCC
TGTCCCTCTGAAGCGCTCAAGCAGCATTCCCCTCACGAGGTTCCCCCACACTAGAGGCCTGTGC
GAGCCTCAGTCGAGGAATCTCGAGATCTGTGCAGCATACGCCCTTGCAGCATTGTTGTTGAGGG
AGTTGGGGTGTTGGCAGGCGTTGGAGACTTGTGCGCCAAGGGGCTGAGCATTCATATGCAGTTG
GTGGCGCGGGGGCGGGGACCTCCCGGGTAAGCCTCGGGCCAAATCTAGCTTGTGTCTGTTAAGG
GAATTGCGGGGAACCTGCCCAGCTGCGCCCTGTGTGTGACTGATCGCGTGTATTTCGGAGGAGT
GAGATCTGACTTGGGGATTCTCCTTGGGGGCGCTGGGACCACTGAACAGATTTTACGGAGGAGA
ACGCCGAGGTCCAAAGAGGCCCCCAGACCCACGGAGGCTAGGACCATCCTTGCTGCGCGTGCGC
AGTAACTTCGGCTGCACGTGCGCATTAACTCTGGCTGCACAGCGAAGCCCTGGGATAACACCGG
CGCCCCCGCAACATGGCAGACGAAGACCTCATCTTCCGCCTGGAAGGTGTTGACGGTGGCGGGT
CCTCCGGAGCTGGCCGCCATGGGGACTCTGACACAGACAGTGACGATGATGAGGGCTACTTCAT
CTGCCCCATCACTGATGACCACATGTCCAACCAGAATGTCAACTCCAAAGGCCAGGGCTACTAC
AACAACCTACTGAAAACGGAGTGTGGCTCCACAGGGTCACCAGCCAGCTCCTTCCACTTCAAGG
AGGCCTGGAAGCATGCGATCGAGAAGGCCAAGCACATGCCCGACCCCTGGGCTGAATTCCATCT
GGAGGACATCGCCACAGAGCATGCTACTCGGCACAGGTACAATGCTGTCACCGGGGAGTGGCTG
AAAGACGAGGTTCTGATCAAGATGGCATCTCAGCCCTTCGGCCGTGGAGCAATGAGGGAGTGCT
TCAGGACGAAGAAACTCTCCAACTTCTTGCATGCCCAGCATTGGAAGGGGGCCTCCAACTACGT
GGCAAAACGCTACCTCGAGCCAGTGGACAGGAGCGTGTACTTTGAGGATGTGCAGCTCCAGATG
GAAGCGAAGCTCTGGGGGGAGGAGTACAACCGGCACAAGCCCCCCAAGCAGGTAGATATCATGC
AGATGTGCATCATTGAGCTAAAGGACAGACAAGGACAGCCCCTCTTCCACCTGGAGCACTACAT
TGAGGGCAAGTACATCAAGTATAATTCCAACTCAGGCTTTGTCCGTGATGACAACATCAGACTA
ACACCACAGGCCTTCAGCCATTTCACATTTGAACGTTCTGGTCATCAGCTGATTGTAGTGGACA
TCCAGGGTGTGGGCGACCTTTATACTGACCCACAGATCCACACTGAGAAAGGCACTGACTTTGG
AGATGGTAACCTTGGTGTCCGGGGAATGGCTCTCTTCTTCTACTCTCATGCCTGCAACCGTATT
TGCCAGAGCATGGGCCTTGCGCCCTTTGACCTCTCCCCACGGGAGCAGGATGCCGTGAACCAGA
GCACCAAGCTGTTGCAATCAGCCAAGACCATCTTGAGGGGGACAGAGGAGAAGTGTGGGAGTCC
CCGCATAAGGACACTCTCTGGCAGCCGGCCCCCCTTGCTCCTTCGCCTGTCAGAGAACTCTGGG
GATGAGAACATGAGTGATGTGACCTTTGACTCTCTGCCTTCCTCCCCGTCTTCAGCCACACCAC
ACAGCCAGAAGTTGGACCACCTCCATTGGCCAGTGTTTGGTGACCTCGATAACATGGGCCCTAG
AGACCATGACCGCATGGACAATCACCGGGACTCTGAGAATAGTGGGGACAGTGGGTATCCAAGC
GAGAAGCGAAGTGACCTGGATGATCCTGAGCCCCGAGAACACGGCCACTCCAATGGCAACCGAA
GGCCTGAATCTGATGAGGACAGCCTGGGCAGCTCTGGACGGGTCTGTGTGGAGACGTGGAACCT
GCTCAATCCCTCCCGCCTGCACCTGCCCAGGCCCTCGGCCGTGGCCCTAGAAGTGCAAAGGTTA
AATGCTCTGGACCTTGGAAGGAAAATCGGGAAGTCTGTTTTGGGGAAGGTCCATCTGGCCATGG
TACGGTACCACGAGGGCGGGCGCTTCTGCGAGAAGGATGAGGAATGGGATCAAGAGTCTGCCAT
CTTCCATCTGGAGCATGCAGCCGACCTGGGAGAACTGGAGGCCATCGTGGGCCTAGGCCTCATG
TACTCTCAGCTGCCCCACCACATCCTGGCTGATGTCTCTCTGGAGGAGACAGAAGAGAACAAGA
CAAAAGGCTTTGATTACCTCCTGAAGGCCGCAGAAGCTGGTGACAGGCAGTCCATGATTTTAGT
GGCTCGAGCTTTTGACACCGGCCTGAACCTCAGCCCAGACAGGTGTCAAGACTGGTCGGAAGCC
TTACACTGGTACAACACGGCCCTGGAGACGACGGACTGCGATGAAGGCGGGGAGTATGACGGAA
TACAGGACGAGCCCCAGTATGCACTGCTGGCCAGGGAGGCAGAGATGTTGCTCACCGGTGGATT
TGGACTGGACAAGAACCCCCAAAGATCAGGAGACTTGTACACCCAGGCAGCCGAGGCAGCAATG
GAAGCCATGAAGGGCCGGCTAGCCAACCAGTACTATGAGAAGGCGGAAGAGGCCTGGGCGCAAA
TGGAGGAATAACTGTCCACAGGATCACTGCCGAGGAGAAGGGCTGGGGAGGGGAGGATGGGACC
CATTTCTTTTGGGAGGGGAGAAGTAGTTTTACTATGGTATAAATTCACTTTTGTATTGCCTTTT
TTTGACTCTTGACAGTCTTTGCAGCTGGCAGAGACATTATAACTGCCCTTTTAGGGGTGGTATT
TTGGGGGAGTGGGGGGTTGAAGATGCAGCCTAATGAATTCTTTTTCCCCCTG

hide sequence

RefSeq Acc Id:

XM_006230158 ⟹ XP_006230220

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	175,403,809 - 175,454,452 (+)	NCBI
Rnor_6.0	1	190,789,781 - 190,839,926 (+)	NCBI
Rnor_5.0	1	197,704,669 - 197,766,058 (+)	NCBI

Sequence:

show sequence

AATAGCTGTTCCCTGAGGACCCCTAAAAATCTTGACTTTGCTGCTACTGGGACATCTAGGTCCC
CTTCTGGAGAGATCCTGGCTTCTAGAGAATAGCTGCTCCCTGAGGACCCCTGAAGAATCTTGGC
TTTGCTGCTACTCGGACATCCAGGTCCCCTTTGGCTAATATTCAAGGCTCAGCCTCACAATTTA
CAAAGCTGAAGATGAGTCTTGTGCCGTACTAGAGAGCTAACTGACGGCTATGCTTCCACATCCC
AGGTTCATGGTATGGCAGGGAGAGAGGAAGGACGTAGAACTCTTCGGAGAAACTTCTCCTCAGG
TGTGTCTAGAACTCTCCGGAGAAACTTCTCCTCAGGTGTGTCTGGCTAGAAGTGGGTACCTAAG
TGAGTAACTTCTGGAAATTTCTCATTTCCTGTGAACTGGGGTCTCTCTCCTTCCTTGGGTTTGG
GAATCCATAATAGGTTGAGTTTGCTAGGAGGCTGGGGTCTGAGGTAAGGTCCCAGGTACTGTCT
GGTGTGCAGAGTGAGGTCGGCCACCAAGCTGCAACTCTGCATTGAGCTGGTTTTCCTAAAGTGT
CCCTCCCTAGCAGGGGACCTTGTCATAAGGAATATGACCTTTTATGCTATGAGAGAGAGAGAGC
ATTGCTGGAGCCAATATAATTAGCAACTTGAAGTAAGGGGAGGAAAGAAAAGGACAATAAATCA
CCTTACAGGTTTGATATCAAAGTACGGTGTTTGTGAGTCCGTGACTAGGATGCTGCCCCATGAT
ATGAGACCTATGTGCTGTGCCTCTGCCAGCCTCTGGATCTGGCTTGTACTTCATGGCCTATCAC
AGTTGCCTAAACGGTAGAGGCACCTGCCGCCAAGCCTACTGACGTGTTCAGTCCCTGGAACCCA
CATGGTAGGAGGAGACTCCCACTTGTGTCCCCGGACCTCCACGTGTTCTTTGCAGAGAGCCCCC
TGACCCAAATTAAACAAACTGAATGTTAAAACACCACCAACAAACTAACCCTTCCTCAAAGTTG
TACACAGCCTTTCTGCTTCTGTTTCATCAAGCTTGGGTGTGTGACGTTGGGAAACCATTTCCAC
AGAGCTGATAAACCTCCCCTCTGAAGAGAGAAGCTCAGAAAGCTACAAGATTAACTGGGCTCCT
GAGCTTATAGACAGTGAGCAGTTACTGGGGACAGACACTGCAGCCAGCAAGGTAGCAAGATAGC
CCACAAGGAGCTCGGGGTTGCAGCTTTCCTGAGTCCTCAAGAGTGCTGGGGCTGGCTTTAGCTG
ATGCAGCTGCTGCTCCTGACCATCCTTGCTGCGCGTGCGCAGTAACTTCGGCTGCACGTGCGCA
TTAACTCTGGCTGCACAGCGAAGCCCTGGGATAACACCGGCGCCCCCGCAACATGGCAGACGAA
GACCTCATCTTCCGCCTGGAAGGTGTTGACGGTGGCGGGTCCTCCGGAGCTGGCCGCCATGGGG
ACTCTGACACAGACAGTGACGATGATGAGGGCTACTTCATCTGCCCCATCACTGATGACCACAT
GTCCAACCAGAATGTCAACTCCAAAGGCCAGGGCTACTACAACAACCTACTGAAAACGGAGTGT
GGCTCCACAGGGTCACCAGCCAGCTCCTTCCACTTCAAGGAGGCCTGGAAGCATGCGATCGAGA
AGGCCAAGCACATGCCCGACCCCTGGGCTGAATTCCATCTGGAGGACATCGCCACAGAGCATGC
TACTCGGCACAGGTACAATGCTGTCACCGGGGAGTGGCTGAAAGACGAGGTTCTGATCAAGATG
GCATCTCAGCCCTTCGGCCGTGGAGCAATGAGGGAGTGCTTCAGGACGAAGAAACTCTCCAACT
TCTTGCATGCCCAGCATTGGAAGGGGGCCTCCAACTACGTGGCAAAACGCTACCTCGAGCCAGT
GGACAGGAGCGTGTACTTTGAGGATGTGCAGCTCCAGATGGAAGCGAAGCTCTGGGGGGAGGAG
TACAACCGGCACAAGCCCCCCAAGCAGGTAGATATCATGCAGATGTGCATCATTGAGCTAAAGG
ACAGACAAGGACAGCCCCTCTTCCACCTGGAGCACTACATTGAGGGCAAGTACATCAAGTATAA
TTCCAACTCAGGCTTTGTCCGTGATGACAACATCAGACTAACACCACAGGCCTTCAGCCATTTC
ACATTTGAACGTTCTGGTCATCAGCTGATTGTAGTGGACATCCAGGGTGTGGGCGACCTTTATA
CTGACCCACAGATCCACACTGAGAAAGGCACTGACTTTGGAGATGGTAACCTTGGTGTCCGGGG
AATGGCTCTCTTCTTCTACTCTCATGCCTGCAACCGTATTTGCCAGAGCATGGGCCTTGCGCCC
TTTGACCTCTCCCCACGGGAGCAGGATGCCGTGAACCAGAGCACCAAGCTGTTGCAATCAGCCA
AGACCATCTTGAGGGGGACAGAGGAGAAGTGTGGGAGTCCCCGCATAAGGACACTCTCTGGCAG
CCGGCCCCCCTTGCTCCTTCGCCTGTCAGAGAACTCTGGGGATGAGAACATGAGTGATGTGACC
TTTGACTCTCTGCCTTCCTCCCCGTCTTCAGCCACACCACACAGCCAGAAGTTGGACCACCTCC
ATTGGCCAGTGTTTGGTGACCTCGATAACATGGGCCCTAGAGACCATGACCGCATGGACAATCA
CCGGGACTCTGAGAATAGTGGGGACAGTGGGTATCCAAGCGAGAAGCGAAGTGACCTGGATGAT
CCTGAGCCCCGAGAACACGGCCACTCCAATGGCAACCGAAGGCCTGAATCTGATGAGGACAGCC
TGGGCAGCTCTGGACGGGTCTGTGTGGAGACGTGGAACCTGCTCAATCCCTCCCGCCTGCACCT
GCCCAGGCCCTCGGCCGTGGCCCTAGAAGTGCAAAGGTTAAATGCTCTGGACCTTGGAAGGAAA
ATCGGGAAGTCTGTTTTGGGGAAGGTCCATCTGGCCATGGTACGGTACCACGAGGGCGGGCGCT
TCTGCGAGAAGGATGAGGAATGGGATCAAGAGTCTGCCATCTTCCATCTGGAGCATGCAGCCGA
CCTGGGAGAACTGGAGGCCATCGTGGGCCTAGGCCTCATGTACTCTCAGCTGCCCCACCACATC
CTGGCTGATGTCTCTCTGGAGGAGACAGAAGAGAACAAGACAAAAGGCTTTGATTACCTCCTGA
AGGCCGCAGAAGCTGGTGACAGGCAGTCCATGATTTTAGTGGCTCGAGCTTTTGACACCGGCCT
GAACCTCAGCCCAGACAGGTGTCAAGACTGGTCGGAAGCCTTACACTGGTACAACACGGCCCTG
GAGACGACGGACTGCGATGAAGGCGGGGAGTATGACGGAATACAGGACGAGCCCCAGTATGCAC
TGCTGGCCAGGGAGGCAGAGATGTTGCTCACCGGTGGATTTGGACTGGACAAGAACCCCCAAAG
ATCAGGAGACTTGTACACCCAGGCAGCCGAGGCAGCAATGGAAGCCATGAAGGGCCGGCTAGCC
AACCAGTACTATGAGAAGGCGGAAGAGGCCTGGGCGCAAATGGAGGAATAACTGTCCACAGGAT
CACTGCCGAGGAGAAGGGCTGGGGAGGGGAGGATGGGACCCATTTCTTTTGGGAGGGGAGAAGT
AGTTTTACTATGGTATAAATTCACTTTTGTATTGCCTTTTTTTGACTCTTGACAGTCTTTGCAG
CTGGCAGAGACATTATAACTGCCCTTTTAGGGGTGGTATTTTGGGGGAGTGGGGGGTTGAAGAT
GCAGCCTAATGAATTCTTTTTCCCCCTG

hide sequence

RefSeq Acc Id:

XM_039101738 ⟹ XP_038957666

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	175,393,119 - 175,454,446 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_037079	(Get FASTA)	NCBI Sequence Viewer
	XP_006230219	(Get FASTA)	NCBI Sequence Viewer
	XP_006230220	(Get FASTA)	NCBI Sequence Viewer
	XP_038957666	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB58272	(Get FASTA)	NCBI Sequence Viewer
	AAH61825	(Get FASTA)	NCBI Sequence Viewer
	CAA65286	(Get FASTA)	NCBI Sequence Viewer
	EDM17599	(Get FASTA)	NCBI Sequence Viewer
	EDM17600	(Get FASTA)	NCBI Sequence Viewer
	EDM17601	(Get FASTA)	NCBI Sequence Viewer
	EDM17602	(Get FASTA)	NCBI Sequence Viewer
	EDM17603	(Get FASTA)	NCBI Sequence Viewer
	EDM17604	(Get FASTA)	NCBI Sequence Viewer
	P70531	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_037079 ⟸ NM_012947

- UniProtKB:

O09089 (UniProtKB/Swiss-Prot), P70531 (UniProtKB/Swiss-Prot), A6I8S8 (UniProtKB/TrEMBL), Q6P757 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MADEDLIFRLEGVDGGGSSGAGRHGDSDTDSDDDEGYFICPITDDHMSNQNVNSKGQGYYNNLL
KTECGSTGSPASSFHFKEAWKHAIEKAKHMPDPWAEFHLEDIATEHATRHRYNAVTGEWLKDEV
LIKMASQPFGRGAMRECFRTKKLSNFLHAQHWKGASNYVAKRYLEPVDRSVYFEDVQLQMEAKL
WGEEYNRHKPPKQVDIMQMCIIELKDRQGQPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQA
FSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFYSHACNRICQSM
GLAPFDLSPREQDAVNQSTKLLQSAKTILRGTEEKCGSPRIRTLSGSRPPLLLRLSENSGDENM
SDVTFDSLPSSPSSATPHSQKLDHLHWPVFGDLDNMGPRDHDRMDNHRDSENSGDSGYPSEKRS
DLDDPEPREHGHSNGNRRPESDEDSLGSSGRVCVETWNLLNPSRLHLPRPSAVALEVQRLNALD
LGRKIGKSVLGKVHLAMVRYHEGGRFCEKDEEWDQESAIFHLEHAADLGELEAIVGLGLMYSQL
PHHILADVSLEETEENKTKGFDYLLKAAEAGDRQSMILVARAFDTGLNLSPDRCQDWSEALHWY
NTALETTDCDEGGEYDGIQDEPQYALLAREAEMLLTGGFGLDKNPQRSGDLYTQAAEAAMEAMK
GRLANQYYEKAEEAWAQMEE

hide sequence

RefSeq Acc Id:	XP_006230219 ⟸ XM_006230157
- Peptide Label:	isoform X1
- UniProtKB:	O09089 (UniProtKB/Swiss-Prot), P70531 (UniProtKB/Swiss-Prot), A6I8S8 (UniProtKB/TrEMBL), Q6P757 (UniProtKB/TrEMBL)
- Sequence:	show sequence MADEDLIFRLEGVDGGGSSGAGRHGDSDTDSDDDEGYFICPITDDHMSNQNVNSKGQGYYNNLL KTECGSTGSPASSFHFKEAWKHAIEKAKHMPDPWAEFHLEDIATEHATRHRYNAVTGEWLKDEV LIKMASQPFGRGAMRECFRTKKLSNFLHAQHWKGASNYVAKRYLEPVDRSVYFEDVQLQMEAKL WGEEYNRHKPPKQVDIMQMCIIELKDRQGQPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQA FSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFYSHACNRICQSM GLAPFDLSPREQDAVNQSTKLLQSAKTILRGTEEKCGSPRIRTLSGSRPPLLLRLSENSGDENM SDVTFDSLPSSPSSATPHSQKLDHLHWPVFGDLDNMGPRDHDRMDNHRDSENSGDSGYPSEKRS DLDDPEPREHGHSNGNRRPESDEDSLGSSGRVCVETWNLLNPSRLHLPRPSAVALEVQRLNALD LGRKIGKSVLGKVHLAMVRYHEGGRFCEKDEEWDQESAIFHLEHAADLGELEAIVGLGLMYSQL PHHILADVSLEETEENKTKGFDYLLKAAEAGDRQSMILVARAFDTGLNLSPDRCQDWSEALHWY NTALETTDCDEGGEYDGIQDEPQYALLAREAEMLLTGGFGLDKNPQRSGDLYTQAAEAAMEAMK GRLANQYYEKAEEAWAQMEE hide sequence

RefSeq Acc Id:	XP_006230220 ⟸ XM_006230158
- Peptide Label:	isoform X1
- UniProtKB:	O09089 (UniProtKB/Swiss-Prot), P70531 (UniProtKB/Swiss-Prot), A6I8S8 (UniProtKB/TrEMBL), Q6P757 (UniProtKB/TrEMBL)
- Sequence:	show sequence MADEDLIFRLEGVDGGGSSGAGRHGDSDTDSDDDEGYFICPITDDHMSNQNVNSKGQGYYNNLL KTECGSTGSPASSFHFKEAWKHAIEKAKHMPDPWAEFHLEDIATEHATRHRYNAVTGEWLKDEV LIKMASQPFGRGAMRECFRTKKLSNFLHAQHWKGASNYVAKRYLEPVDRSVYFEDVQLQMEAKL WGEEYNRHKPPKQVDIMQMCIIELKDRQGQPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQA FSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFYSHACNRICQSM GLAPFDLSPREQDAVNQSTKLLQSAKTILRGTEEKCGSPRIRTLSGSRPPLLLRLSENSGDENM SDVTFDSLPSSPSSATPHSQKLDHLHWPVFGDLDNMGPRDHDRMDNHRDSENSGDSGYPSEKRS DLDDPEPREHGHSNGNRRPESDEDSLGSSGRVCVETWNLLNPSRLHLPRPSAVALEVQRLNALD LGRKIGKSVLGKVHLAMVRYHEGGRFCEKDEEWDQESAIFHLEHAADLGELEAIVGLGLMYSQL PHHILADVSLEETEENKTKGFDYLLKAAEAGDRQSMILVARAFDTGLNLSPDRCQDWSEALHWY NTALETTDCDEGGEYDGIQDEPQYALLAREAEMLLTGGFGLDKNPQRSGDLYTQAAEAAMEAMK GRLANQYYEKAEEAWAQMEE hide sequence

RefSeq Acc Id:

ENSRNOP00000022726 ⟸ ENSRNOT00000022726

RefSeq Acc Id:	XP_038957666 ⟸ XM_039101738
- Peptide Label:	isoform X2
- UniProtKB:	Q6P757 (UniProtKB/TrEMBL)

Protein Domains

Alpha-type protein kinase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P70531-F1-model_v2	AlphaFold	P70531	1-724	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:2538	AgrOrtholog
BioCyc Gene	G2FUF-57595	BioCyc
Ensembl Genes	ENSRNOG00000016448	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSRNOP00000022726	ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000022726	ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH	1.25.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MHCK/EF2 kinase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:5599075	IMAGE-MGC_LOAD
InterPro	eEF-2K	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	eEF2K_a_kinase_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Kinase-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MHCK_EF2_kinase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Sel1-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TPR-like_helical_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:25435	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:72540	IMAGE-MGC_LOAD
NCBI Gene	25435	ENTREZGENE
PANTHER	EUKARYOTIC ELONGATION FACTOR 2 KINASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	EUKARYOTIC ELONGATION FACTOR 2 KINASE-RELATED	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Alpha_kinase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Sel1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Eef2k	PhenoGen
PIRSF	Elongation_factor_2_kinase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	ALPHA_KINASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	Alpha_kinase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	HCP-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF56112	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR	TC204086
UniProt	A6I8S8	ENTREZGENE, UniProtKB/TrEMBL
	A6I8T0_RAT	UniProtKB/TrEMBL
	EF2K_RAT	UniProtKB/Swiss-Prot
	O09089	ENTREZGENE
	P70531	ENTREZGENE
	Q6P757	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	O09089	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2002-06-10	Eef2k	Eukaryotic elongation factor 2 kinase			Symbol and Name status set to approved	70586	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Annotations - PID (archival)