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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:chrysanthemic acid
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Accession:CHEBI:3680 term browser browse the term
Definition:A monocarboxylic acid that is cyclopropanecarboxylic acid substituted by two methyl groups at position 2 and a 2-methylprop-1-en-1-yl group at position 3.
Synonyms:exact_synonym: 2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropanecarboxylic acid
 related_synonym: Chrysanthemumsaeure;   Formula=C10H16O2;   InChI=1S/C10H16O2/c1-6(2)5-7-8(9(11)12)10(7,3)4/h5,7-8H,1-4H3,(H,11,12);   InChIKey=XLOPRKKSAJMMEW-UHFFFAOYSA-N;   SMILES=CC(C)=CC1C(C(O)=O)C1(C)C;   chrysanthemummonocarboxylic acid
 xref: Beilstein:2043418;   CAS:10453-89-1;   KEGG:C09842;   LINCS:LSM-21601;   PMID:13083;   PMID:16328989;   PMID:17226179;   PMID:24253739;   Patent:CN101830795;   Patent:US2010210721


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(+)-trans-(S)-allethrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme decreases activity ISO bioallethrin results in decreased activity of ACE protein CTD PMID:32097678 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Cat catalase decreases activity ISO bioallethrin results in decreased activity of CAT protein CTD PMID:32097678 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ces1d carboxylesterase 1D increases metabolic processing ISO CES1 protein results in increased metabolism of bioallethrin CTD PMID:19249324 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 multiple interactions ISO [DDT co-treated with bioallethrin] results in increased expression of CHRM4 mRNA CTD PMID:10192214 NCBI chr 3:80,833,272...80,841,165
Ensembl chr 3:80,833,272...80,841,006
JBrowse link
G Glo1 glyoxalase 1 increases activity ISO bioallethrin results in increased activity of GLO1 protein CTD PMID:32097678 NCBI chr20:9,273,589...9,291,608
Ensembl chr20:9,273,594...9,291,610
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity ISO bioallethrin results in decreased activity of GSR protein CTD PMID:32097678 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Ifng interferon gamma multiple interactions
decreases expression
affects expression
ISO [bioallethrin co-treated with Piperonyl Butoxide] results in increased expression of IFNG protein
bioallethrin results in decreased expression of IFNG mRNA
bioallethrin affects the expression of IFNG protein
CTD PMID:9860237, PMID:10414782, PMID:12755381 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il4 interleukin 4 multiple interactions
affects expression
ISO [bioallethrin co-treated with Piperonyl Butoxide] results in increased expression of IL4 protein
bioallethrin affects the expression of IL4 protein
CTD PMID:9860237, PMID:10414782 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO
EXP
bioallethrin results in increased activity of NR1I2 protein CTD PMID:19249324 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 affects activity EXP bioallethrin affects the activity of SCN10A protein CTD PMID:19766671 NCBI chr 8:128,298,593...128,416,896
Ensembl chr 8:128,298,594...128,416,650
JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 multiple interactions EXP bioallethrin affects the reaction [[SCN2B protein co-treated with SCN1B protein co-treated with SCN8A protein mutant form] results in increased transport of Sodium] CTD PMID:22465659 NCBI chr 1:89,550,738...89,560,469
Ensembl chr 1:89,550,738...89,560,719
JBrowse link
G Scn2b sodium voltage-gated channel beta subunit 2 multiple interactions EXP bioallethrin affects the reaction [[SCN2B protein co-treated with SCN1B protein co-treated with SCN8A protein mutant form] results in increased transport of Sodium] CTD PMID:22465659 NCBI chr 8:49,419,003...49,431,110
Ensembl chr 8:49,418,965...49,427,689
JBrowse link
G Scn8a sodium voltage-gated channel alpha subunit 8 multiple interactions EXP bioallethrin affects the reaction [[SCN2B protein co-treated with SCN1B protein co-treated with SCN8A protein mutant form] results in increased transport of Sodium] CTD PMID:22465659 NCBI chr 7:142,575,629...142,683,659
Ensembl chr 7:142,575,672...142,684,114
JBrowse link
allethrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Allethrins results in increased expression of BAX protein CTD PMID:24055895 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO
EXP
Allethrins results in decreased expression of BCL2 protein CTD PMID:24055895, PMID:25072698 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO Allethrins inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA] CTD PMID:32473317 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Brdt bromodomain testis associated decreases expression EXP Allethrins results in decreased expression of BRDT mRNA CTD PMID:28181402 NCBI chr14:3,437,876...3,462,613
Ensembl chr14:3,405,995...3,462,629
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A multiple interactions EXP Allethrins inhibits the reaction [CACNA1A protein results in increased transport of Calcium] CTD PMID:14634047 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C multiple interactions EXP Allethrins inhibits the reaction [CACNA1C protein results in increased transport of Calcium] CTD PMID:14634047 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G multiple interactions EXP Allethrins inhibits the reaction [CACNA1G protein results in increased transport of Calcium] CTD PMID:14634047 NCBI chr10:82,129,071...82,197,828
Ensembl chr10:82,129,506...82,197,848
JBrowse link
G Casp3 caspase 3 increases activity
decreases expression
ISO
EXP
Allethrins results in increased activity of CASP3 protein
Allethrins results in decreased expression of CASP3 protein
CTD PMID:24055895, PMID:25072698 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase affects activity EXP Allethrins affects the activity of CAT protein CTD PMID:23595975, PMID:25072698 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP Allethrins results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:22080754 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions EXP Allethrins results in increased expression of and results in increased activity of CYP3A2 protein CTD PMID:22080754 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Ddx25 DEAD-box helicase 25 decreases expression EXP Allethrins results in decreased expression of DDX25 mRNA CTD PMID:28181402 NCBI chr 8:36,744,686...36,760,720
Ensembl chr 8:36,744,667...36,760,742
JBrowse link
G Defb22 defensin beta 22 decreases expression EXP Allethrins results in decreased expression of DEFB22 mRNA CTD PMID:23595975 NCBI chr 3:147,961,818...147,966,097
Ensembl chr 3:147,961,818...147,966,097
JBrowse link
G Hsf2 heat shock transcription factor 2 decreases expression EXP Allethrins results in decreased expression of HSF2 mRNA CTD PMID:28181402 NCBI chr20:38,935,820...38,963,444
Ensembl chr20:38,935,820...38,963,309
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Allethrins results in increased expression of IL1B mRNA CTD PMID:24055895 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Ins2 insulin 2 multiple interactions ISO Allethrins inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Allethrins inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA] CTD PMID:32473317 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Kdm3a lysine demethylase 3A decreases expression EXP Allethrins results in decreased expression of KDM3A mRNA CTD PMID:28181402 NCBI chr 4:99,503,160...99,547,315
Ensembl chr 4:99,503,176...99,546,905
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase decreases expression EXP Allethrins results in decreased expression of KIT mRNA CTD PMID:28181402 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610
JBrowse link
G Kitlg KIT ligand decreases expression EXP Allethrins results in decreased expression of KITLG mRNA CTD PMID:28181402 NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases expression EXP Allethrins results in increased expression of MAPK1 protein modified form CTD PMID:23595975 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases expression EXP Allethrins results in increased expression of MAPK3 protein modified form CTD PMID:23595975 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression ISO Allethrins results in increased expression of MMP9 protein CTD PMID:24055895 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mtf1 metal-regulatory transcription factor 1 increases activity ISO Allethrins results in increased activity of MTF1 protein CTD PMID:20143881 NCBI chr 5:142,797,340...142,843,896
Ensembl chr 5:142,797,366...142,842,122
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases activity ISO Allethrins results in increased activity of MYC protein CTD PMID:20143881 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO Allethrins results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Ovol1 ovo like transcriptional repressor 1 decreases expression EXP Allethrins results in decreased expression of OVOL1 mRNA CTD PMID:28181402 NCBI chr 1:220,927,309...220,938,814
Ensembl chr 1:220,925,605...220,938,814
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions EXP Allethrins results in decreased expression of and results in increased cleavage of PARP1 protein CTD PMID:25072698 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases activity
increases expression
ISO Allethrins results in increased activity of PPARG protein
Allethrins results in increased expression of PPARG mRNA
CTD PMID:20143881, PMID:32473317 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Rara retinoic acid receptor, alpha increases activity ISO Allethrins results in increased activity of RARA protein CTD PMID:20143881 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 multiple interactions EXP Allethrins affects the reaction [SCN10A protein results in increased transport of Sodium] CTD PMID:16051293 NCBI chr 8:128,298,593...128,416,896
Ensembl chr 8:128,298,594...128,416,650
JBrowse link
G Sp1 Sp1 transcription factor increases activity ISO Allethrins results in increased activity of SP1 protein CTD PMID:20143881 NCBI chr 7:144,014,173...144,044,635
Ensembl chr 7:144,014,173...144,044,629
JBrowse link
G Sp7 Sp7 transcription factor multiple interactions ISO Allethrins inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA] CTD PMID:32473317 NCBI chr 7:143,957,316...143,967,488
Ensembl chr 7:143,958,858...143,967,484
JBrowse link
G Spag11bl sperm associated antigen 11b-like decreases expression EXP Allethrins results in decreased expression of SPAG11A mRNA CTD PMID:23595975 NCBI chr16:75,145,234...75,148,750
Ensembl chr16:75,145,401...75,147,415
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression EXP Allethrins results in decreased expression of STAR mRNA CTD PMID:28181402 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression EXP Allethrins results in decreased expression of TGFB1 mRNA CTD PMID:23595975 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tnf tumor necrosis factor increases expression ISO Allethrins results in increased expression of TNF mRNA CTD PMID:24055895 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 affects expression
decreases expression
increases expression
EXP Allethrins affects the expression of TP53 protein
Allethrins results in decreased expression of TP53 mRNA
Allethrins results in increased expression of TP53 mRNA
CTD PMID:22356257, PMID:23595975, PMID:25072698 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Wnt10b Wnt family member 10B increases expression ISO Allethrins results in increased expression of WNT10B mRNA CTD PMID:12437293 NCBI chr 7:140,448,284...140,466,159
Ensembl chr 7:140,448,465...140,454,268
JBrowse link
G Ybx2 Y box binding protein 2 decreases expression EXP Allethrins results in decreased expression of YBX2 mRNA CTD PMID:28181402 NCBI chr10:56,546,689...56,552,339
Ensembl chr10:56,546,710...56,551,863
JBrowse link
bifenthrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression ISO bifenthrin results in increased expression of ABCB1B mRNA CTD PMID:26071804 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Ache acetylcholinesterase multiple interactions
decreases expression
EXP bifenthrin results in decreased expression of and results in decreased activity of ACHE protein
bifenthrin results in decreased expression of ACHE mRNA
CTD PMID:29775722 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) increases expression ISO bifenthrin results in increased expression of ADH1 mRNA CTD PMID:26071804 NCBI chr 2:243,550,655...243,562,243
Ensembl chr 2:243,550,627...243,687,857
JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide increases expression ISO bifenthrin results in increased expression of ADH5 mRNA CTD PMID:26071804 NCBI chr 2:243,728,500...243,740,907
Ensembl chr 2:243,700,784...243,740,899
JBrowse link
G Ahr aryl hydrocarbon receptor increases expression ISO bifenthrin results in increased expression of AHR mRNA CTD PMID:26071804 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression ISO bifenthrin results in increased expression of ALDH1A1 mRNA CTD PMID:26071804 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type decreases expression ISO bifenthrin results in decreased expression of ALOX12 mRNA CTD PMID:26071804 NCBI chr10:56,851,734...56,864,049
Ensembl chr10:56,851,734...56,864,005
JBrowse link
G Alox15 arachidonate 15-lipoxygenase increases expression ISO bifenthrin results in increased expression of ALOX15 mRNA CTD PMID:26071804 NCBI chr10:56,953,692...56,962,145
Ensembl chr10:56,953,691...56,962,161
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO bifenthrin inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] CTD PMID:29149346 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO bifenthrin results in increased expression of APAF1 mRNA CTD PMID:26071804 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Apoe apolipoprotein E increases expression ISO bifenthrin results in increased expression of APOE mRNA CTD PMID:26071804 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Areg amphiregulin multiple interactions EXP bifenthrin inhibits the reaction [CGA protein results in increased expression of AREG mRNA] CTD PMID:21251947 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases expression ISO bifenthrin results in increased expression of ARNT mRNA CTD PMID:26071804 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO bifenthrin results in decreased expression of BCL2 mRNA CTD PMID:26071804, PMID:27916261 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO bifenthrin results in increased expression of BID mRNA CTD PMID:26071804 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Brca1 BRCA1, DNA repair associated affects binding ISO bifenthrin binds to BRCA1 protein CTD PMID:32278787 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Casp3 caspase 3 increases activity
increases expression
ISO bifenthrin results in increased activity of CASP3 protein
bifenthrin results in increased expression of CASP3 mRNA
CTD PMID:26071804, PMID:27916261 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases activity
decreases expression
ISO bifenthrin results in increased activity of CASP8 protein
bifenthrin results in decreased expression of CASP8 mRNA
CTD PMID:26071804 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Cat catalase multiple interactions
decreases activity
decreases expression
increases expression
affects activity
ISO
EXP
Quercetin inhibits the reaction [bifenthrin results in decreased activity of CAT protein]; Rutin inhibits the reaction [bifenthrin results in decreased activity of CAT protein]
bifenthrin results in decreased expression of CAT protein
bifenthrin analog results in increased expression of CAT mRNA; bifenthrin results in increased expression of CAT mRNA
bifenthrin affects the activity of CAT protein; bifenthrin analog affects the activity of CAT protein
CTD PMID:19833193, PMID:23172818, PMID:25149237, PMID:27916261, PMID:29775722, PMID:29793499, PMID:30102949, PMID:32061760, PMID:32408700 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccne1 cyclin E1 multiple interactions EXP bifenthrin inhibits the reaction [CGA protein results in increased expression of CCNE1 mRNA] CTD PMID:21251947 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Cd36 CD36 molecule increases expression ISO bifenthrin results in increased expression of CD36 mRNA CTD PMID:29554630 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions EXP bifenthrin inhibits the reaction [CGA protein results in increased expression of CDKN1A mRNA] CTD PMID:21251947 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions EXP bifenthrin inhibits the reaction [CGA protein results in increased expression of CEBPB mRNA] CTD PMID:21251947 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Ces2h carboxylesterase 2H increases metabolic processing ISO CES2 protein results in increased metabolism of bifenthrin CTD PMID:19249324 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Cga glycoprotein hormones, alpha polypeptide multiple interactions
increases secretion
EXP
ISO
bifenthrin analog inhibits the reaction [CGA protein results in increased abundance of Progesterone]; bifenthrin analog inhibits the reaction [CGA protein results in increased secretion of Dinoprostone]; bifenthrin analog inhibits the reaction [CGA results in increased expression of CYP11A1 mRNA]; bifenthrin analog inhibits the reaction [CGA results in increased expression of DBI mRNA]; bifenthrin analog inhibits the reaction [CGA results in increased expression of PTGS2 mRNA]; bifenthrin analog inhibits the reaction [CGA results in increased expression of STAR mRNA]; bifenthrin analog inhibits the reaction [CGA results in increased expression of TSPO mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of AREG mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of CCNE1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of CDKN1A mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of CEBPB mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of CYP11A1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of CYP19A1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of EREG mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of PGR mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of PTGS2 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of RUNX1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of STAR mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of SULT1E1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of TGFB1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased secretion of Dinoprostone]
fulvestrant inhibits the reaction [bifenthrin results in increased secretion of CGA protein]
CTD PMID:21251947, PMID:21871944, PMID:24938463 NCBI chr 5:50,362,491...50,393,368
Ensembl chr 5:50,381,244...50,393,367
JBrowse link
G Chat choline O-acetyltransferase decreases expression EXP bifenthrin results in decreased expression of CHAT mRNA CTD PMID:29775722 NCBI chr16:8,576,858...8,686,131
Ensembl chr16:8,577,840...8,686,131
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 decreases expression EXP bifenthrin results in decreased expression of CHRM1 mRNA CTD PMID:29775722 NCBI chr 1:224,869,087...224,885,101
Ensembl chr 1:224,882,439...224,884,205
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A decreases expression ISO bifenthrin results in decreased expression of CPT1A mRNA CTD PMID:29554630 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression ISO bifenthrin results in decreased expression of CXCL1 mRNA CTD PMID:28251819 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 increases expression ISO bifenthrin results in increased expression of CYB5R3 mRNA CTD PMID:26071804 NCBI chr 7:124,024,003...124,041,564
Ensembl chr 7:124,023,995...124,041,594
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions
decreases expression
EXP
ISO
bifenthrin analog inhibits the reaction [CGA results in increased expression of CYP11A1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of CYP11A1 mRNA]
bifenthrin results in decreased expression of CYP11A1 mRNA
CTD PMID:21251947, PMID:21871944, PMID:23994515, PMID:24449165 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 increases expression
decreases expression
ISO bifenthrin results in increased expression of CYP17A1 mRNA
bifenthrin results in decreased expression of CYP17A1 mRNA
CTD PMID:23994515, PMID:24449165, PMID:24938463, PMID:26071804 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions
increases expression
EXP
ISO
bifenthrin inhibits the reaction [CGA protein results in increased expression of CYP19A1 mRNA]
bifenthrin results in increased expression of CYP19A1 mRNA
CTD PMID:21251947, PMID:24938463 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
decreases expression
EXP
ISO
bifenthrin results in increased activity of CYP1A1 protein
bifenthrin results in decreased expression of CYP1A1 mRNA
CTD PMID:20009351, PMID:26071804 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases expression ISO bifenthrin results in increased expression of CYP2C29 mRNA CTD PMID:26071804 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression ISO bifenthrin results in increased expression of CYP2E1 mRNA CTD PMID:26071804 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 decreases expression ISO bifenthrin results in decreased expression of CYP4B1 mRNA CTD PMID:26071804 NCBI chr 5:134,508,728...134,526,103
Ensembl chr 5:134,508,730...134,526,089
JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein multiple interactions EXP bifenthrin analog inhibits the reaction [CGA results in increased expression of DBI mRNA] CTD PMID:21871944 NCBI chr13:36,147,667...36,156,076
Ensembl chr13:36,117,119...36,174,908
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression ISO bifenthrin results in increased expression of EPHX1 mRNA CTD PMID:26071804 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 affects binding ISO bifenthrin binds to ERBB2 protein CTD PMID:32278787 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Ereg epiregulin multiple interactions EXP bifenthrin inhibits the reaction [CGA protein results in increased expression of EREG mRNA] CTD PMID:21251947 NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394
JBrowse link
G Esr1 estrogen receptor 1 decreases expression
affects binding
ISO bifenthrin results in decreased expression of ESR1 mRNA
bifenthrin binds to ESR1 protein
CTD PMID:20097460, PMID:32278787 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Faim Fas apoptotic inhibitory molecule decreases expression ISO bifenthrin results in decreased expression of FAIM mRNA CTD PMID:26071804 NCBI chr 8:107,225,119...107,247,228
Ensembl chr 8:107,225,212...107,241,224
Ensembl chr 8:107,225,212...107,241,224
JBrowse link
G Faslg Fas ligand decreases expression ISO bifenthrin results in decreased expression of FASL mRNA CTD PMID:26071804 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fasn fatty acid synthase increases expression ISO bifenthrin results in increased expression of FASN mRNA CTD PMID:29554630 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fbp1 fructose-bisphosphatase 1 increases expression ISO bifenthrin results in increased expression of FBP1 mRNA CTD PMID:26071804 NCBI chr17:396,175...417,480
Ensembl chr17:396,180...417,480
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 affects binding ISO bifenthrin binds to FGFR2 protein CTD PMID:32278787 NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 increases expression ISO bifenthrin results in increased expression of GGT1 mRNA CTD PMID:26071804 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 increases expression ISO bifenthrin results in increased expression of GNRH1 mRNA CTD PMID:24938463 NCBI chr15:44,441,856...44,446,064
Ensembl chr15:44,442,555...44,442,875
Ensembl chr15:44,442,555...44,442,875
JBrowse link
G Gnrhr gonadotropin releasing hormone receptor increases expression ISO bifenthrin results in increased expression of GNRHR mRNA CTD PMID:24938463 NCBI chr14:23,480,462...23,498,450
Ensembl chr14:23,480,462...23,498,450
JBrowse link
G Gpi glucose-6-phosphate isomerase increases expression ISO bifenthrin results in increased expression of GPI1 mRNA CTD PMID:26071804 NCBI chr 1:90,063,411...90,091,287
Ensembl chr 1:90,063,411...90,091,287
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression
decreases expression
ISO bifenthrin results in increased expression of GPX1 mRNA
bifenthrin results in decreased expression of GPX1 mRNA
CTD PMID:26071804, PMID:27916261 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression
decreases expression
ISO bifenthrin results in increased expression of GPX2 mRNA
bifenthrin results in decreased expression of GPX2 mRNA
CTD PMID:26071804, PMID:27916261 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression ISO bifenthrin results in increased expression of GPX3 mRNA CTD PMID:26071804 NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression ISO bifenthrin results in increased expression of GSTA1 mRNA CTD PMID:26071804, PMID:27916261 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression ISO bifenthrin results in increased expression of GSTA3 mRNA CTD PMID:26071804 NCBI chr 9:27,357,490...27,417,023
Ensembl chr 9:27,402,381...27,417,023
JBrowse link
G Gsta6 glutathione S-transferase alpha 6 increases expression ISO bifenthrin results in increased expression of GSTA1 mRNA CTD PMID:26071804, PMID:27916261 NCBI chr 9:27,475,273...27,533,939
Ensembl chr 9:27,475,273...27,511,176
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression ISO bifenthrin results in increased expression of GSTM1 mRNA CTD PMID:26071804 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression ISO bifenthrin results in increased expression of GSTM2 mRNA CTD PMID:26071804 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 increases expression ISO bifenthrin results in increased expression of GSTM5 mRNA CTD PMID:26071804 NCBI chr 2:210,685,338...210,688,133
Ensembl chr 2:210,685,197...210,688,272
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression ISO bifenthrin results in increased expression of GSTP1 mRNA CTD PMID:26071804 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hk2 hexokinase 2 increases expression ISO bifenthrin results in increased expression of HK2 mRNA CTD PMID:26071804 NCBI chr 4:113,559,396...113,609,897
Ensembl chr 4:113,559,427...113,610,243
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO bifenthrin analog results in increased expression of HMOX1 mRNA; bifenthrin results in increased expression of HMOX1 mRNA CTD PMID:25149237, PMID:27916261 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 decreases expression ISO bifenthrin results in decreased expression of HSD17B1 mRNA CTD PMID:24938463 NCBI chr10:88,987,558...88,989,758
Ensembl chr10:88,987,558...88,989,757
JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 decreases expression ISO bifenthrin results in decreased expression of HSD17B3 mRNA CTD PMID:26071804 NCBI chr17:1,579,319...1,610,745
Ensembl chr17:1,579,319...1,610,745
JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 increases expression ISO bifenthrin results in increased expression of HSD3B2 mRNA CTD PMID:24938463 NCBI chr 2:200,712,895...200,722,429
Ensembl chr 2:202,341,422...202,350,929
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A decreases expression ISO bifenthrin results in decreased expression of HSPA1A protein CTD PMID:16271832 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO bifenthrin results in increased expression of HSPA5 protein CTD PMID:16271832 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression ISO bifenthrin results in decreased expression of HSPA8 protein CTD PMID:16271832 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspb2 heat shock protein family B (small) member 2 decreases expression ISO bifenthrin results in decreased expression of HSPB2 protein CTD PMID:16271832 NCBI chr 8:55,176,648...55,178,227
Ensembl chr 8:55,176,847...55,177,818
JBrowse link
G Il1b interleukin 1 beta decreases expression
increases expression
multiple interactions
ISO
EXP
bifenthrin results in decreased expression of IL1B mRNA
bifenthrin results in increased expression of IL1B mRNA
bifenthrin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B mRNA]
CTD PMID:27916261, PMID:28251819, PMID:30102949 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 increases expression ISO bifenthrin results in increased expression of IL2 mRNA CTD PMID:23172818 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il4 interleukin 4 increases expression ISO bifenthrin results in increased expression of IL4 mRNA CTD PMID:23172818 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 decreases expression
increases expression
multiple interactions
ISO
EXP
bifenthrin results in decreased expression of IL6 mRNA
bifenthrin results in increased expression of IL6 protein
bifenthrin results in increased expression of IL6 mRNA
bifenthrin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]
CTD PMID:27916261, PMID:28251819, PMID:29793499, PMID:30102949, PMID:32061760 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ldlr low density lipoprotein receptor decreases expression ISO bifenthrin results in decreased expression of LDLR mRNA CTD PMID:24449165, PMID:32408700 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO bifenthrin analog results in increased phosphorylation of MAPK1 protein CTD PMID:19442700 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO bifenthrin analog results in increased phosphorylation of MAPK3 protein CTD PMID:19442700 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 decreases expression ISO bifenthrin results in decreased expression of MGST2 mRNA CTD PMID:26071804 NCBI chr 2:140,708,396...140,727,381
Ensembl chr 2:140,708,397...140,727,281
JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 increases expression ISO bifenthrin results in increased expression of MGST3 mRNA CTD PMID:26071804 NCBI chr13:85,601,499...85,622,392
Ensembl chr13:85,601,499...85,622,314
JBrowse link
G Mt2A metallothionein 2A increases expression ISO bifenthrin results in increased expression of MT2 mRNA CTD PMID:26071804 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mt3 metallothionein 3 increases expression ISO bifenthrin results in increased expression of MT3 mRNA CTD PMID:26071804 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
G Mthfr methylenetetrahydrofolate reductase increases expression ISO bifenthrin results in increased expression of MTHFR mRNA CTD PMID:26071804 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Nat1 N-acetyltransferase 1 increases expression ISO bifenthrin results in increased expression of NAT1 mRNA CTD PMID:26071804 NCBI chr16:23,970,742...23,991,573
Ensembl chr16:23,970,743...23,991,573
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 decreases expression
increases expression
EXP
ISO
bifenthrin results in decreased expression of NFE2L2 mRNA; bifenthrin results in decreased expression of NFE2L2 protein
bifenthrin results in increased expression of NFE2L2 mRNA; bifenthrin results in increased expression of NFE2L2 protein
CTD PMID:29775722, PMID:29793499, PMID:30102949, PMID:32061760 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression
affects binding
ISO bifenthrin results in decreased expression of NQO1 mRNA
bifenthrin binds to NQO1 protein
CTD PMID:27916261, PMID:32278787 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO bifenthrin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
increases expression
affects binding
ISO
EXP
bifenthrin results in increased activity of NR1I2 protein
bifenthrin results in increased expression of NR1I2 mRNA; bifenthrin results in increased expression of NR1I2 protein
bifenthrin binds to NR1I2 protein
CTD PMID:19249324, PMID:29554630 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO bifenthrin inhibits the reaction [Hydrocortisone results in increased activity of NR3C1 protein] CTD PMID:26647222 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 multiple interactions ISO bifenthrin inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]; bifenthrin inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein] CTD PMID:29149346 NCBI chr19:34,408,275...34,761,003
Ensembl chr19:34,448,289...34,752,695
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions EXP bifenthrin inhibits the reaction [Hydrocortisone results in increased expression of PCK1 mRNA] CTD PMID:26647222 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871
JBrowse link
G Pgr progesterone receptor multiple interactions
increases expression
EXP
ISO
bifenthrin inhibits the reaction [CGA protein results in increased expression of PGR mRNA]
fulvestrant inhibits the reaction [bifenthrin results in increased expression of PGR mRNA]
bifenthrin results in increased expression of PGR; bifenthrin results in increased expression of PGR mRNA
CTD PMID:21251947, PMID:24938463 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Pklr pyruvate kinase L/R decreases expression ISO bifenthrin results in decreased expression of PKLR mRNA CTD PMID:26071804 NCBI chr 2:188,449,158...188,458,034
Ensembl chr 2:188,449,210...188,459,592
JBrowse link
G Pkm pyruvate kinase M1/2 increases expression ISO bifenthrin results in increased expression of PKM mRNA CTD PMID:26071804 NCBI chr 8:64,480,963...64,502,957
Ensembl chr 8:64,481,172...64,502,722
JBrowse link
G Pon1 paraoxonase 1 increases expression ISO bifenthrin results in increased expression of PON1 mRNA CTD PMID:26071804 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Pon3 paraoxonase 3 increases expression ISO bifenthrin results in increased expression of PON3 mRNA CTD PMID:26071804 NCBI chr 4:30,311,981...30,338,679
Ensembl chr 4:30,311,982...30,338,679
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta affects binding ISO bifenthrin binds to PPARD protein CTD PMID:32278787 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO bifenthrin results in increased expression of PPARG mRNA CTD PMID:29554630 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ptges prostaglandin E synthase increases expression EXP
ISO
bifenthrin results in increased expression of PTGES mRNA; bifenthrin results in increased expression of PTGES protein CTD PMID:29775722, PMID:29793499, PMID:30102949, PMID:32061760 NCBI chr 3:9,727,408...9,738,752
Ensembl chr 3:9,727,408...9,738,752
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
EXP
ISO
bifenthrin analog inhibits the reaction [CGA results in increased expression of PTGS2 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of PTGS2 mRNA]; bifenthrin inhibits the reaction [Colforsin results in increased expression of PTGS2 mRNA]
bifenthrin results in increased expression of PTGS2 mRNA; bifenthrin results in increased expression of PTGS2 protein
CTD PMID:21251947, PMID:21871944, PMID:29775722, PMID:29793499, PMID:30102949, PMID:32061760 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases expression EXP
ISO
bifenthrin results in increased expression of RELA mRNA; bifenthrin results in increased expression of RELA protein CTD PMID:29775722, PMID:29793499, PMID:30102949, PMID:32061760 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rora RAR-related orphan receptor A affects binding ISO bifenthrin binds to RORA protein CTD PMID:32278787 NCBI chr 8:75,515,886...75,616,477
Ensembl chr 8:75,516,904...75,607,212
JBrowse link
G Rorc RAR-related orphan receptor C affects binding ISO bifenthrin binds to RORC protein CTD PMID:32278787 NCBI chr 2:195,612,471...195,636,797
Ensembl chr 2:195,617,021...195,637,630
JBrowse link
G Runx1 RUNX family transcription factor 1 multiple interactions EXP bifenthrin inhibits the reaction [CGA protein results in increased expression of RUNX1 mRNA] CTD PMID:21251947 NCBI chr11:32,765,147...33,003,061
Ensembl chr11:32,769,165...33,003,021
JBrowse link
G Scarb1 scavenger receptor class B, member 1 decreases expression ISO bifenthrin results in decreased expression of SCARB1 mRNA CTD PMID:23994515 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO bifenthrin results in increased expression of SCD mRNA CTD PMID:29554630 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 multiple interactions EXP bifenthrin affects the reaction [SCN10A protein results in increased transport of Sodium] CTD PMID:16051293 NCBI chr 8:128,298,593...128,416,896
Ensembl chr 8:128,298,594...128,416,650
JBrowse link
G Shbg sex hormone binding globulin affects binding ISO bifenthrin binds to SHBG protein CTD PMID:32278787 NCBI chr10:56,219,861...56,237,354
Ensembl chr10:56,219,858...56,223,245
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
increases expression
EXP
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bifenthrin analog results in increased expression of SOD1 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [bifenthrin analog results in increased expression of SOD1 protein]
bifenthrin analog results in increased expression of SOD1 mRNA; bifenthrin results in increased expression of SOD1 mRNA
CTD PMID:22718203, PMID:25149237, PMID:27916261 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression
EXP
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bifenthrin analog results in increased expression of SOD2 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [bifenthrin analog results in increased expression of SOD2 protein]
bifenthrin results in increased expression of SOD2 mRNA
CTD PMID:22718203, PMID:27916261 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase affects binding ISO bifenthrin binds to SRC protein CTD PMID:32278787 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 decreases expression ISO bifenthrin results in decreased expression of SRD5A2 mRNA CTD PMID:26071804 NCBI chr 6:25,279,635...25,315,501
Ensembl chr 6:25,279,626...25,315,511
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions
decreases expression
EXP
ISO
bifenthrin analog inhibits the reaction [CGA results in increased expression of STAR mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of STAR mRNA]
bifenthrin results in decreased expression of STAR mRNA
CTD PMID:21251947, PMID:21871944, PMID:23994515 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 multiple interactions EXP bifenthrin inhibits the reaction [CGA protein results in increased expression of SULT1E1 mRNA] CTD PMID:21251947 NCBI chr14:22,070,861...22,089,264
Ensembl chr14:22,072,024...22,089,248
JBrowse link
G Tff1 trefoil factor 1 increases expression ISO bifenthrin results in increased expression of TFF1 mRNA CTD PMID:20097460 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP bifenthrin inhibits the reaction [CGA protein results in increased expression of TGFB1 mRNA] CTD PMID:21251947 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
decreases expression
ISO
EXP
bifenthrin results in increased expression of TNF mRNA
bifenthrin results in increased expression of TNF protein
bifenthrin results in increased expression of TNF mRNA; bifenthrin results in increased expression of TNF protein
bifenthrin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF mRNA]
bifenthrin results in decreased expression of TNF mRNA
CTD PMID:23172818, PMID:26071804, PMID:27916261, PMID:28251819, PMID:29775722, PMID:29793499, PMID:30102949, PMID:32061760 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 increases expression
decreases expression
ISO bifenthrin results in increased expression of TRP53 mRNA
bifenthrin results in decreased expression of TRP53 mRNA
CTD PMID:20097460, PMID:26071804, PMID:27916261 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tspo translocator protein multiple interactions
decreases expression
EXP
ISO
bifenthrin analog inhibits the reaction [CGA results in increased expression of TSPO mRNA]
bifenthrin results in decreased expression of TSPO mRNA
CTD PMID:21871944, PMID:23994515, PMID:24449165 NCBI chr 7:124,460,358...124,470,610
Ensembl chr 7:124,460,358...124,470,609
JBrowse link
bioresmethrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ces1d carboxylesterase 1D multiple interactions
increases hydrolysis
increases metabolic processing
ISO
EXP
27-hydroxycholesterol inhibits the reaction [CES1 protein results in increased metabolism of bioresmethrin]
CES1 protein results in increased hydrolysis of bioresmethrin
CTD PMID:16387282, PMID:19249324, PMID:19761868 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO
EXP
bioresmethrin results in increased activity of NR1I2 protein CTD PMID:19249324 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
kadethrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO kadethrin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
phenothrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 decreases expression
affects binding
ISO phenothrin results in decreased expression of ESR1 protein
phenothrin binds to ESR1 protein
CTD PMID:15118252, PMID:32278787 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 decreases expression ISO phenothrin results in decreased expression of ESR2 protein CTD PMID:15118252 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO phenothrin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO phenothrin affects the localization of and results in increased activity of NR1I3 protein CTD PMID:30247703 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Tff1 trefoil factor 1 multiple interactions
increases expression
ISO ICI 164384 inhibits the reaction [phenothrin results in increased expression of TFF1 mRNA] CTD PMID:10064545, PMID:15118252 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
JBrowse link
G Vdr vitamin D receptor affects binding ISO phenothrin binds to VDR protein CTD PMID:32278787 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
G Wnt10b Wnt family member 10B increases expression ISO phenothrin results in increased expression of WNT10B mRNA CTD PMID:12437293 NCBI chr 7:140,448,284...140,466,159
Ensembl chr 7:140,448,465...140,454,268
JBrowse link
prallethrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO d,d-T80-prallethrin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA] CTD PMID:32473317 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions ISO d,d-T80-prallethrin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA] CTD PMID:32473317 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Ins2 insulin 2 multiple interactions ISO d,d-T80-prallethrin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; d,d-T80-prallethrin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; d,d-T80-prallethrin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA] CTD PMID:32473317 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO d,d-T80-prallethrin results in increased expression of PPARG mRNA CTD PMID:32473317 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Sp7 Sp7 transcription factor multiple interactions ISO d,d-T80-prallethrin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA] CTD PMID:32473317 NCBI chr 7:143,957,316...143,967,488
Ensembl chr 7:143,958,858...143,967,484
JBrowse link
G Xbp1 X-box binding protein 1 increases activity ISO d,d-T80-prallethrin results in increased activity of XBP1 protein CTD PMID:20143881 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
pyrethrins term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator affects expression ISO Pyrethrins affects the expression of BAX protein CTD PMID:27939866 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator affects expression ISO Pyrethrins affects the expression of BCL2 protein CTD PMID:27939866 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO Pyrethrins inhibits the reaction [Potassium results in increased expression of BDNF mRNA] CTD PMID:15527870 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Casp3 caspase 3 increases activity ISO Pyrethrins results in increased activity of CASP3 protein CTD PMID:27939866 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 increases activity ISO Pyrethrins results in increased activity of CASP9 protein CTD PMID:27939866 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP Pyrethrins results in increased expression of CYP2B1 mRNA CTD PMID:18022748 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP Pyrethrins results in increased expression of CYP2B2 mRNA CTD PMID:18022748 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO Pyrethrins results in increased expression of CYP2B6 mRNA CTD PMID:18022748 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Pyrethrins inhibits the reaction [Potassium results in increased expression of FOS mRNA] CTD PMID:15527870 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO Pyrethrins binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Pyrethrins results in increased cleavage of PARP1 protein CTD PMID:27939866 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO Pyrethrins binds to and results in increased activity of PPARA protein CTD PMID:17084873 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
resmethrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 decreases activity ISO resmethrin results in decreased activity of ABCG2 protein CTD PMID:23169446 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Amh anti-Mullerian hormone increases expression ISO resmethrin results in increased expression of AMH mRNA CTD PMID:31593228 NCBI chr 7:11,775,155...11,777,503
Ensembl chr 7:11,775,155...11,777,503
JBrowse link
G Ddx4 DEAD-box helicase 4 decreases expression ISO resmethrin results in decreased expression of DDX4 mRNA CTD PMID:31593228 NCBI chr 2:44,447,610...44,504,263
Ensembl chr 2:44,447,573...44,504,354
JBrowse link
G Esr1 estrogen receptor 1 affects binding ISO resmethrin binds to ESR1 protein CTD PMID:32278787 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Gfra1 GDNF family receptor alpha 1 decreases expression ISO resmethrin results in decreased expression of GFRA1 mRNA CTD PMID:31593228 NCBI chr 1:279,203,046...279,572,789 JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO resmethrin results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO resmethrin inhibits the reaction [Hydrocortisone results in increased activity of NR3C1 protein] CTD PMID:26647222 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases activity ISO resmethrin results in increased activity of PPARG protein CTD PMID:20143881 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Sohlh1 spermatogenesis and oogenesis specific basic helix-loop-helix 1 decreases expression ISO resmethrin results in decreased expression of SOHLH1 mRNA CTD PMID:31593228 NCBI chr 3:3,290,766...3,295,226
Ensembl chr 3:3,291,084...3,295,101
JBrowse link
G Sohlh2 spermatogenesis and oogenesis specific basic helix-loop-helix 2 decreases expression ISO resmethrin results in decreased expression of SOHLH2 mRNA CTD PMID:31593228 NCBI chr 2:144,591,755...144,614,065
Ensembl chr 2:144,591,755...144,614,064
JBrowse link
G Sox9 SRY-box transcription factor 9 increases expression ISO resmethrin results in increased expression of SOX9 mRNA CTD PMID:31593228 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
JBrowse link
G Stra8 stimulated by retinoic acid 8 decreases expression ISO resmethrin results in decreased expression of STRA8 mRNA CTD PMID:31593228 NCBI chr 4:62,447,724...62,474,802
Ensembl chr 4:62,457,694...62,473,360
JBrowse link
G Sycp3 synaptonemal complex protein 3 decreases expression ISO resmethrin results in decreased expression of SYCP3 mRNA CTD PMID:31593228 NCBI chr 7:29,029,887...29,044,344
Ensembl chr 7:29,029,263...29,044,251
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO resmethrin inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:26647222 NCBI chr  X:111,884,285...111,944,693
Ensembl chr  X:111,884,295...111,887,906
JBrowse link
G Wt1 WT1 transcription factor increases expression ISO resmethrin results in increased expression of WT1 mRNA CTD PMID:31593228 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564
JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 decreases expression ISO resmethrin results in decreased expression of ZBTB16 mRNA CTD PMID:31593228 NCBI chr 8:52,980,226...53,146,765
Ensembl chr 8:52,985,313...53,146,953
JBrowse link
tetramethrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions
decreases expression
ISO tetramethrin results in decreased activity of [Dihydrotestosterone results in increased activity of AR protein]
tetramethrin results in decreased expression of AR mRNA
CTD PMID:12711008, PMID:16621434 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Brca1 BRCA1, DNA repair associated affects binding ISO tetramethrin binds to BRCA1 protein CTD PMID:32278787 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Ces2h carboxylesterase 2H multiple interactions
increases metabolic processing
ISO CES2 protein inhibits the reaction [tetramethrin results in increased activity of NR1I2 protein]
CES2 protein results in increased metabolism of tetramethrin
CTD PMID:19249324 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Esr1 estrogen receptor 1 decreases expression EXP tetramethrin results in decreased expression of ESR1 protein CTD PMID:16326440 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 increases expression EXP tetramethrin results in increased expression of ESR2 protein CTD PMID:16326440 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Folh1 folate hydrolase 1 decreases expression ISO tetramethrin results in decreased expression of FOLH1 mRNA CTD PMID:12711008 NCBI chr 1:150,323,768...150,395,415
Ensembl chr 1:150,323,768...150,395,415
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO tetramethrin inhibits the reaction [IGF1 protein results in increased import of Calcium] CTD PMID:1550224, PMID:2460452, PMID:2539779 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf2 insulin-like growth factor 2 multiple interactions ISO tetramethrin inhibits the reaction [IGF2 protein results in increased import of Calcium] CTD PMID:2442157, PMID:2539779 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO tetramethrin results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Nkx3-1 NK3 homeobox 1 decreases expression ISO tetramethrin results in decreased expression of NKX3-1 mRNA CTD PMID:12711008 NCBI chr15:51,065,316...51,067,908
Ensembl chr15:51,065,316...51,068,421
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
ISO
EXP
CES2 protein inhibits the reaction [tetramethrin results in increased activity of NR1I2 protein] CTD PMID:19249324 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO [Diethylhexyl Phthalate co-treated with butylparaben co-treated with tetramethrin co-treated with propylparaben] results in increased activity of NR3C1 protein; [Diethylhexyl Phthalate co-treated with butylparaben co-treated with tetramethrin] results in increased activity of NR3C1 protein; [tetramethrin co-treated with propylparaben] results in increased activity of NR3C1 protein CTD PMID:25448277 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G S100g S100 calcium binding protein G decreases expression
multiple interactions
EXP tetramethrin results in decreased expression of S100G mRNA
tetramethrin inhibits the reaction [Estradiol results in increased expression of S100G mRNA]
CTD PMID:16326440 NCBI chr  X:33,442,820...33,445,714
Ensembl chr  X:33,443,186...33,445,709
JBrowse link
G Shbg sex hormone binding globulin affects binding ISO tetramethrin binds to SHBG protein CTD PMID:32278787 NCBI chr10:56,219,861...56,237,354
Ensembl chr10:56,219,858...56,223,245
JBrowse link
G Tmprss2 transmembrane serine protease 2 increases expression ISO tetramethrin results in increased expression of TMPRSS2 mRNA CTD PMID:12711008 NCBI chr11:38,063,914...38,103,406
Ensembl chr11:38,063,915...38,103,290
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        biochemical role 19282
          metabolite 19263
            eukaryotic metabolite 18908
              plant metabolite 17360
                chrysanthemic acid 181
                  (EZ)-(1R)-empenthrin 0
                  allethrin + 50
                  cis-chrysanthemic acid + 115
                  cyphenothrin + 0
                  epsilon-momfluorothrin 0
                  imiprothrin 0
                  phenothrin + 7
                  prallethrin 6
                  resmethrin + 18
                  tetramethrin + 15
                  trans-chrysanthemic acid + 24
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              organic divalent group 18488
                                organodiyl group 18488
                                  carbonyl group 18391
                                    carbonyl compound 18391
                                      carboxylic acid 18061
                                        monocarboxylic acid 17407
                                          cyclopropanecarboxylic acid 738
                                            chrysanthemic acid 181
                                              (EZ)-(1R)-empenthrin 0
                                              allethrin + 50
                                              cis-chrysanthemic acid + 115
                                              cyphenothrin + 0
                                              epsilon-momfluorothrin 0
                                              imiprothrin 0
                                              phenothrin + 7
                                              prallethrin 6
                                              resmethrin + 18
                                              tetramethrin + 15
                                              trans-chrysanthemic acid + 24
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.