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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3770
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Star
Name: steroidogenic acute regulatory protein
Acc ID: CHEBI:3093
Term: bifenthrin
Definition: A carboxylic ester obtained by formal condensation of cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylic acid and [(2-methyl-1,1'-biphenyl)-3-yl]methanol.
Chemical ID: MESH:C099952
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Starmultiple interactionsEXP 6480464CTDbifenthrin analog inhibits the reaction [CGA results in increased expression of STAR mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of STAR mRNA]PMID:21251947 PMID:21871944
Stardecreases expressionISOStar (Mus musculus)6480464CTDbifenthrin results in decreased expression of STAR mRNAPMID:23994515
Stardecreases expressionISOSTAR (Homo sapiens)6480464CTDbifenthrin results in decreased expression of STAR mRNA; bifenthrin results in decreased expression of STAR proteinPMID:34896276
Starmultiple interactionsISOSTAR (Homo sapiens)6480464CTDbifenthrin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR mRNA]; bifenthrin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR protein]PMID:34896276
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