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Gene: Usp4 (ubiquitin specific peptidase 4) Rattus norvegicus
Symbol: Usp4
Name: ubiquitin specific peptidase 4
Description: Predicted to have adenosine receptor binding activity; identical protein binding activity; and thiol-dependent ubiquitin-specific protease activity. Predicted to be involved in several processes, including negative regulation of protein ubiquitination; protein localization to cell surface; and spliceosomal tri-snRNP complex assembly. Predicted to localize to the cytosol; nucleus; and plasma membrane. Orthologous to human USP4 (ubiquitin specific peptidase 4); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; benzo[a]pyrene; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: deubiquitinating enzyme 4; LOC290864; similar to Ubiquitin carboxyl-terminal hydrolase 4 (Ubiquitin thiolesterase 4) (Ubiquitin-specific processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein); ubiquitin carboxyl-terminal hydrolase 4; ubiquitin specific peptidase 4 (proto-oncogene); ubiquitin specific protease 4; ubiquitin specific protease 4 (proto-oncogene); ubiquitin thioesterase 4; ubiquitin-specific-processing protease 4
Homo sapiens (human) : USP4 (ubiquitin specific peptidase 4)  HGNC  Alliance
Mus musculus (house mouse) : Usp4 (ubiquitin specific peptidase 4 (proto-oncogene))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Usp4 (ubiquitin specific peptidase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : USP4 (ubiquitin specific peptidase 4)
Canis lupus familiaris (dog) : USP4 (ubiquitin specific peptidase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Usp4 (ubiquitin specific peptidase 4)
Sus scrofa (pig) : USP4 (ubiquitin specific peptidase 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.08117,126,692 - 117,171,012 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,126,692 - 117,171,012 (+)Ensembl
Rnor_5.08116,474,812 - 116,519,375 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera8108,338,833 - 108,383,118 (+)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Usp4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1587387
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.