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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cis-chrysanthemic acid
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Accession:CHEBI:39103 term browser browse the term
Synonyms:exact_synonym: rel-(1R,3S)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropanecarboxylic acid
 related_synonym: (1R,3S)-rel-2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylic acid;   Formula=C10H16O2;   chrysanthemic acid dl-cis-form;   cis-(1)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylic acid;   cis-Chrysanthemumsaeure
 xref: Beilstein:3196386;   CAS:2935-23-1



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bifenthrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression ISO bifenthrin results in increased expression of ABCB1B mRNA CTD PMID:26071804 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Ache acetylcholinesterase multiple interactions
decreases expression
EXP bifenthrin results in decreased expression of and results in decreased activity of ACHE protein
bifenthrin results in decreased expression of ACHE mRNA; bifenthrin results in decreased expression of ACHE protein
CTD PMID:29775722 PMID:30978409 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Adh1 alcohol dehydrogenase 1C (class I), gamma polypeptide increases expression ISO bifenthrin results in increased expression of ADH1 mRNA CTD PMID:26071804 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide increases expression ISO bifenthrin results in increased expression of ADH5 mRNA CTD PMID:26071804 NCBI chr 2:226,975,184...226,987,591
Ensembl chr 2:226,947,466...226,987,591
JBrowse link
G Ahr aryl hydrocarbon receptor increases expression ISO bifenthrin results in increased expression of AHR mRNA CTD PMID:26071804 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression ISO bifenthrin results in increased expression of ALDH1A1 mRNA CTD PMID:26071804 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type decreases expression ISO bifenthrin results in decreased expression of ALOX12 mRNA CTD PMID:26071804 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542
JBrowse link
G Alox15 arachidonate 15-lipoxygenase increases expression ISO bifenthrin results in increased expression of ALOX15 mRNA CTD PMID:26071804 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO bifenthrin inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] CTD PMID:29149346 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO bifenthrin results in increased expression of APAF1 mRNA CTD PMID:26071804 PMID:32408700 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Apoe apolipoprotein E increases expression ISO bifenthrin results in increased expression of APOE mRNA CTD PMID:26071804 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Areg amphiregulin multiple interactions EXP bifenthrin inhibits the reaction [CGA protein results in increased expression of AREG mRNA] CTD PMID:21251947 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases expression ISO bifenthrin results in increased expression of ARNT mRNA CTD PMID:26071804 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO bifenthrin results in increased expression of BAX mRNA CTD PMID:32408700 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bche butyrylcholinesterase decreases activity EXP bifenthrin results in decreased activity of BCHE protein CTD PMID:30978409 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO bifenthrin results in decreased expression of BCL2 mRNA CTD PMID:26071804 PMID:27916261 PMID:32408700 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO bifenthrin results in increased expression of BID mRNA CTD PMID:26071804 PMID:32408700 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Brca1 BRCA1, DNA repair associated affects binding ISO bifenthrin binds to BRCA1 protein CTD PMID:32278787 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Casp3 caspase 3 increases activity
increases expression
ISO
EXP
bifenthrin results in increased activity of CASP3 protein
bifenthrin results in increased expression of CASP3 mRNA
bifenthrin results in increased expression of CASP3 protein
CTD PMID:26071804 PMID:27916261 PMID:30978409 PMID:32408700 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases activity
decreases expression
ISO bifenthrin results in increased activity of CASP8 protein
bifenthrin results in decreased expression of CASP8 mRNA
CTD PMID:26071804 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases expression ISO bifenthrin results in increased expression of CASP9 mRNA CTD PMID:32408700 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions
decreases activity
affects activity
increases expression
decreases expression
ISO
EXP
Quercetin inhibits the reaction [bifenthrin results in decreased activity of CAT protein]; Rutin inhibits the reaction [bifenthrin results in decreased activity of CAT protein]
bifenthrin affects the activity of CAT protein; bifenthrin analog affects the activity of CAT protein
bifenthrin analog results in increased expression of CAT mRNA; bifenthrin results in increased expression of CAT mRNA
bifenthrin results in decreased expression of CAT protein
CTD PMID:19833193 PMID:23172818 PMID:25149237 PMID:27916261 PMID:29775722 More... NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccne1 cyclin E1 multiple interactions EXP bifenthrin inhibits the reaction [CGA protein results in increased expression of CCNE1 mRNA] CTD PMID:21251947 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Cd36 CD36 molecule increases expression ISO bifenthrin results in increased expression of CD36 mRNA CTD PMID:29554630 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions EXP bifenthrin inhibits the reaction [CGA protein results in increased expression of CDKN1A mRNA] CTD PMID:21251947 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions EXP bifenthrin inhibits the reaction [CGA protein results in increased expression of CEBPB mRNA] CTD PMID:21251947 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Ces2h carboxylesterase 2H increases metabolic processing ISO CES2 protein results in increased metabolism of bifenthrin CTD PMID:19249324 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
JBrowse link
G Cga glycoprotein hormones, alpha polypeptide multiple interactions
increases secretion
EXP
ISO
bifenthrin analog inhibits the reaction [CGA protein results in increased abundance of Progesterone]; bifenthrin analog inhibits the reaction [CGA protein results in increased secretion of Dinoprostone]; bifenthrin analog inhibits the reaction [CGA results in increased expression of CYP11A1 mRNA]; bifenthrin analog inhibits the reaction [CGA results in increased expression of DBI mRNA]; bifenthrin analog inhibits the reaction [CGA results in increased expression of PTGS2 mRNA]; bifenthrin analog inhibits the reaction [CGA results in increased expression of STAR mRNA]; bifenthrin analog inhibits the reaction [CGA results in increased expression of TSPO mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of AREG mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of CCNE1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of CDKN1A mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of CEBPB mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of CYP11A1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of CYP19A1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of EREG mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of PGR mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of PTGS2 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of RUNX1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of STAR mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of SULT1E1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of TGFB1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased secretion of Dinoprostone]
fulvestrant inhibits the reaction [bifenthrin results in increased secretion of CGA protein]
CTD PMID:21251947 PMID:21871944 PMID:24938463 NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191
JBrowse link
G Chat choline O-acetyltransferase decreases expression EXP bifenthrin results in decreased expression of CHAT mRNA CTD PMID:29775722 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 decreases expression EXP bifenthrin results in decreased expression of CHRM1 mRNA CTD PMID:29775722 PMID:30978409 NCBI chr 1:205,567,046...205,583,001
Ensembl chr 1:205,567,220...205,582,356
JBrowse link
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit decreases expression EXP bifenthrin results in decreased expression of CHRNA2 mRNA CTD PMID:30978409 NCBI chr15:40,342,317...40,358,601
Ensembl chr15:40,342,317...40,358,601
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A decreases expression ISO bifenthrin results in decreased expression of CPT1A mRNA CTD PMID:29554630 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression ISO bifenthrin results in decreased expression of CXCL1 mRNA CTD PMID:28251819 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 increases expression ISO bifenthrin results in increased expression of CYB5R3 mRNA CTD PMID:26071804 NCBI chr 7:114,306,686...114,324,247
Ensembl chr 7:114,306,685...114,324,298
JBrowse link
G Cycs cytochrome c, somatic increases expression ISO bifenthrin results in increased expression of CYCS mRNA CTD PMID:32408700 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions
decreases expression
EXP
ISO
bifenthrin analog inhibits the reaction [CGA results in increased expression of CYP11A1 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of CYP11A1 mRNA]
bifenthrin results in decreased expression of CYP11A1 mRNA
CTD PMID:21251947 PMID:21871944 PMID:23994515 PMID:24449165 PMID:32408700 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 increases expression
decreases expression
ISO bifenthrin results in increased expression of CYP17A1 mRNA
bifenthrin results in decreased expression of CYP17A1 mRNA
CTD PMID:23994515 PMID:24449165 PMID:24938463 PMID:26071804 PMID:32408700 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions
increases expression
EXP
ISO
bifenthrin inhibits the reaction [CGA protein results in increased expression of CYP19A1 mRNA]
bifenthrin results in increased expression of CYP19A1 mRNA
CTD PMID:21251947 PMID:24938463 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
decreases expression
EXP
ISO
bifenthrin results in increased activity of CYP1A1 protein
bifenthrin results in decreased expression of CYP1A1 mRNA
CTD PMID:20009351 PMID:26071804 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases expression ISO bifenthrin results in increased expression of CYP2C29 mRNA CTD PMID:26071804
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression ISO bifenthrin results in increased expression of CYP2E1 mRNA CTD PMID:26071804 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO bifenthrin results in increased expression of CYP3A4 mRNA CTD PMID:19249324 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 decreases expression ISO bifenthrin results in decreased expression of CYP4B1 mRNA CTD PMID:26071804 NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348
JBrowse link
G Dbi diazepam binding inhibitor multiple interactions EXP bifenthrin analog inhibits the reaction [CGA results in increased expression of DBI mRNA] CTD PMID:21871944 NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression ISO bifenthrin results in increased expression of EPHX1 mRNA CTD PMID:26071804 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 affects binding ISO bifenthrin binds to ERBB2 protein CTD PMID:32278787 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Ereg epiregulin multiple interactions EXP bifenthrin inhibits the reaction [CGA protein results in increased expression of EREG mRNA] CTD PMID:21251947 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062
JBrowse link
G Esr1 estrogen receptor 1 decreases expression
multiple interactions
affects binding
ISO bifenthrin results in decreased expression of ESR1 mRNA
bifenthrin binds to and results in increased activity of ESR1 protein
bifenthrin binds to ESR1 protein
CTD PMID:20097460 PMID:32278787 PMID:33049310 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO bifenthrin binds to and results in increased activity of ESR2 protein CTD PMID:33049310 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Faim Fas apoptotic inhibitory molecule decreases expression ISO bifenthrin results in decreased expression of FAIM mRNA CTD PMID:26071804 NCBI chr 8:99,543,877...99,569,499
Ensembl chr 8:99,542,405...99,560,562
JBrowse link
G Faslg Fas ligand decreases expression ISO bifenthrin results in decreased expression of FASL mRNA CTD PMID:26071804 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fasn fatty acid synthase increases expression
decreases expression
ISO bifenthrin results in increased expression of FASN mRNA
bifenthrin results in decreased expression of FASN mRNA
CTD PMID:29554630 PMID:32408700 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fbp1 fructose-bisphosphatase 1 increases expression ISO bifenthrin results in increased expression of FBP1 mRNA CTD PMID:26071804 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 affects binding ISO bifenthrin binds to FGFR2 protein CTD PMID:32278787 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 increases expression ISO bifenthrin results in increased expression of GGT1 mRNA CTD PMID:26071804 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 increases expression ISO bifenthrin results in increased expression of GNRH1 mRNA CTD PMID:24938463 NCBI chr15:41,972,482...41,976,690
Ensembl chr15:41,972,905...41,973,581
Ensembl chr15:41,972,905...41,973,581
JBrowse link
G Gnrhr gonadotropin releasing hormone receptor increases expression ISO bifenthrin results in increased expression of GNRHR mRNA CTD PMID:24938463 NCBI chr14:21,856,871...21,874,861
Ensembl chr14:21,856,871...21,874,861
JBrowse link
G Gpi glucose-6-phosphate isomerase increases expression ISO bifenthrin results in increased expression of GPI1 mRNA CTD PMID:26071804 NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression
decreases expression
ISO bifenthrin results in increased expression of GPX1 mRNA
bifenthrin results in decreased expression of GPX1 mRNA
CTD PMID:26071804 PMID:27916261 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression
decreases expression
ISO bifenthrin results in increased expression of GPX2 mRNA
bifenthrin results in decreased expression of GPX2 mRNA
CTD PMID:26071804 PMID:27916261 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression ISO bifenthrin results in increased expression of GPX3 mRNA CTD PMID:26071804 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression ISO bifenthrin results in increased expression of GSTA3 mRNA CTD PMID:26071804 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression ISO bifenthrin results in increased expression of GSTA1 mRNA CTD PMID:26071804 PMID:27916261 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression ISO bifenthrin results in increased expression of GSTM1 mRNA CTD PMID:26071804 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression ISO bifenthrin results in increased expression of GSTM2 mRNA CTD PMID:26071804 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 increases expression ISO bifenthrin results in increased expression of GSTM5 mRNA CTD PMID:26071804 NCBI chr 2:195,531,627...195,534,562
Ensembl chr 2:195,531,495...195,534,553
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression ISO bifenthrin results in increased expression of GSTP1 mRNA CTD PMID:26071804 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Hk2 hexokinase 2 increases expression ISO bifenthrin results in increased expression of HK2 mRNA CTD PMID:26071804 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO bifenthrin analog results in increased expression of HMOX1 mRNA; bifenthrin results in increased expression of HMOX1 mRNA CTD PMID:25149237 PMID:27916261 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 decreases expression ISO bifenthrin results in decreased expression of HSD17B1 mRNA CTD PMID:24938463 NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927
JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 decreases expression ISO bifenthrin results in decreased expression of HSD17B3 mRNA CTD PMID:26071804 NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression ISO bifenthrin results in decreased expression of HSD3B1 mRNA CTD PMID:32408700 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 increases expression ISO bifenthrin results in increased expression of HSD3B2 mRNA CTD PMID:24938463 NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A decreases expression ISO bifenthrin results in decreased expression of HSPA1A protein CTD PMID:16271832
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO bifenthrin results in increased expression of HSPA5 protein CTD PMID:16271832 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression ISO bifenthrin results in decreased expression of HSPA8 protein CTD PMID:16271832 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspb2 heat shock protein family B (small) member 2 decreases expression ISO bifenthrin results in decreased expression of HSPB2 protein CTD PMID:16271832 NCBI chr 8:51,093,267...51,094,864
Ensembl chr 8:51,081,342...51,094,533
JBrowse link
G Il1b interleukin 1 beta decreases expression
increases expression
multiple interactions
ISO
EXP
bifenthrin results in decreased expression of IL1B mRNA
bifenthrin results in increased expression of IL1B mRNA
bifenthrin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B mRNA]
CTD PMID:27916261 PMID:28251819 PMID:30102949 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 increases expression ISO bifenthrin results in increased expression of IL2 mRNA CTD PMID:23172818 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il4 interleukin 4 increases expression ISO bifenthrin results in increased expression of IL4 mRNA CTD PMID:23172818 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 decreases expression
increases expression
multiple interactions
ISO
EXP
bifenthrin results in decreased expression of IL6 mRNA
bifenthrin results in increased expression of IL6 protein
bifenthrin results in increased expression of IL6 mRNA
bifenthrin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]
CTD PMID:27916261 PMID:28251819 PMID:29793499 PMID:30102949 PMID:32061760 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ldlr low density lipoprotein receptor decreases expression ISO bifenthrin results in decreased expression of LDLR mRNA CTD PMID:24449165 PMID:32408700 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO bifenthrin analog results in increased phosphorylation of MAPK1 protein CTD PMID:19442700 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO bifenthrin analog results in increased phosphorylation of MAPK3 protein CTD PMID:19442700 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 decreases expression ISO bifenthrin results in decreased expression of MGST2 mRNA CTD PMID:26071804 NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828
JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 increases expression ISO bifenthrin results in increased expression of MGST3 mRNA CTD PMID:26071804 NCBI chr13:79,526,541...79,547,479
Ensembl chr13:79,526,541...79,547,411
JBrowse link
G Mir122 microRNA 122 increases expression ISO bifenthrin results in increased expression of MIR122 mRNA CTD PMID:32408700 NCBI chr18:58,758,703...58,758,787 JBrowse link
G Mir17 microRNA 17 decreases expression ISO bifenthrin results in decreased expression of MIR17 mRNA CTD PMID:32408700 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712
JBrowse link
G Mir34b microRNA 34b decreases expression ISO bifenthrin results in decreased expression of MIR34B mRNA CTD PMID:32408700 NCBI chr 8:51,410,244...51,410,327
Ensembl chr 8:51,410,244...51,410,327
JBrowse link
G Mir34c microRNA 34c decreases expression ISO bifenthrin results in decreased expression of MIR34C mRNA CTD PMID:32408700 NCBI chr 8:51,409,726...51,409,802
Ensembl chr 8:51,409,726...51,409,802
JBrowse link
G Mir449a microRNA 449a decreases expression ISO bifenthrin results in decreased expression of MIR449A mRNA CTD PMID:32408700 NCBI chr 2:44,670,714...44,670,804
Ensembl chr 2:44,670,714...44,670,804
JBrowse link
G Mir449c microRNA 449c decreases expression ISO bifenthrin results in decreased expression of MIR449C mRNA CTD PMID:32408700 NCBI chr 2:44,669,179...44,669,277
Ensembl chr 2:44,669,179...44,669,277
JBrowse link
G Mt2A metallothionein 2A increases expression ISO bifenthrin results in increased expression of MT2 mRNA CTD PMID:26071804 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mt3 metallothionein 3 increases expression ISO bifenthrin results in increased expression of MT3 mRNA CTD PMID:26071804 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158
JBrowse link
G Mthfr methylenetetrahydrofolate reductase increases expression ISO bifenthrin results in increased expression of MTHFR mRNA CTD PMID:26071804 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
JBrowse link
G Nat1 N-acetyltransferase 1 increases expression ISO bifenthrin results in increased expression of NAT1 mRNA CTD PMID:26071804 NCBI chr16:22,218,217...22,238,516
Ensembl chr16:22,208,194...22,238,520
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases expression
increases expression
EXP
ISO
bifenthrin results in decreased expression of NFE2L2 mRNA; bifenthrin results in decreased expression of NFE2L2 protein
bifenthrin results in increased expression of NFE2L2 mRNA; bifenthrin results in increased expression of NFE2L2 protein
CTD PMID:29775722 PMID:29793499 PMID:30102949 PMID:32061760 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression
affects binding
ISO bifenthrin results in decreased expression of NQO1 mRNA
bifenthrin binds to NQO1 protein
CTD PMID:27916261 PMID:32278787 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO bifenthrin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions
increases expression
affects binding
ISO
EXP
bifenthrin results in increased activity of NR1I2 protein
bifenthrin binds to and results in increased activity of NR1I2 protein
bifenthrin results in increased expression of NR1I2 mRNA; bifenthrin results in increased expression of NR1I2 protein
bifenthrin binds to NR1I2 protein
CTD PMID:19249324 PMID:29554630 PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO bifenthrin inhibits the reaction [Hydrocortisone results in increased activity of NR3C1 protein] CTD PMID:26647222 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 multiple interactions ISO bifenthrin inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]; bifenthrin inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein] CTD PMID:29149346 NCBI chr19:30,715,648...31,059,885
Ensembl chr19:30,715,648...31,059,885
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 decreases expression EXP bifenthrin results in decreased expression of NR4A2 mRNA; bifenthrin results in decreased expression of NR4A2 protein CTD PMID:30978409 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions EXP bifenthrin inhibits the reaction [Hydrocortisone results in increased expression of PCK1 mRNA] CTD PMID:26647222 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pgr progesterone receptor multiple interactions
increases expression
EXP
ISO
bifenthrin inhibits the reaction [CGA protein results in increased expression of PGR mRNA]
fulvestrant inhibits the reaction [bifenthrin results in increased expression of PGR mRNA]
bifenthrin results in increased expression of PGR; bifenthrin results in increased expression of PGR mRNA
CTD PMID:21251947 PMID:24938463 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Pklr pyruvate kinase L/R decreases expression ISO bifenthrin results in decreased expression of PKLR mRNA CTD PMID:26071804 NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
JBrowse link
G Pkm pyruvate kinase M1/2 increases expression ISO bifenthrin results in increased expression of PKM mRNA CTD PMID:26071804 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
JBrowse link
G Pon1 paraoxonase 1 increases expression ISO bifenthrin results in increased expression of PON1 mRNA CTD PMID:26071804 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Pon3 paraoxonase 3 increases expression ISO bifenthrin results in increased expression of PON3 mRNA CTD PMID:26071804 NCBI chr 4:33,356,983...33,383,681
Ensembl chr 4:33,349,168...33,383,855
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta affects binding ISO bifenthrin binds to PPARD protein CTD PMID:32278787 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression
multiple interactions
ISO bifenthrin results in increased expression of PPARG mRNA
bifenthrin binds to and results in increased activity of PPARG protein
CTD PMID:29554630 PMID:33049310 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ptges prostaglandin E synthase increases expression EXP
ISO
bifenthrin results in increased expression of PTGES mRNA; bifenthrin results in increased expression of PTGES protein CTD PMID:29775722 PMID:29793499 PMID:30102949 PMID:32061760 NCBI chr 3:14,177,892...14,189,236 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
EXP
ISO
bifenthrin analog inhibits the reaction [CGA results in increased expression of PTGS2 mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of PTGS2 mRNA]; bifenthrin inhibits the reaction [Colforsin results in increased expression of PTGS2 mRNA]
bifenthrin results in increased expression of PTGS2 mRNA; bifenthrin results in increased expression of PTGS2 protein
CTD PMID:21251947 PMID:21871944 PMID:29775722 PMID:29793499 PMID:30102949 More... NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases expression EXP
ISO
bifenthrin results in increased expression of RELA mRNA; bifenthrin results in increased expression of RELA protein CTD PMID:29775722 PMID:29793499 PMID:30102949 PMID:32061760 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rora RAR-related orphan receptor A affects binding ISO bifenthrin binds to RORA protein CTD PMID:32278787 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931
JBrowse link
G Rorc RAR-related orphan receptor C affects binding ISO bifenthrin binds to RORC protein CTD PMID:32278787 NCBI chr 2:182,009,707...182,034,910
Ensembl chr 2:182,009,286...182,034,907
JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [bifenthrin results in increased expression of HLA-G mRNA] CTD PMID:24938463 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117
JBrowse link
G Runx1 RUNX family transcription factor 1 multiple interactions EXP bifenthrin inhibits the reaction [CGA protein results in increased expression of RUNX1 mRNA] CTD PMID:21251947 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542
JBrowse link
G Scarb1 scavenger receptor class B, member 1 decreases expression ISO bifenthrin results in decreased expression of SCARB1 mRNA CTD PMID:23994515 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO bifenthrin results in increased expression of SCD mRNA CTD PMID:29554630 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 multiple interactions EXP bifenthrin affects the reaction [SCN10A protein results in increased transport of Sodium] CTD PMID:16051293 NCBI chr 8:119,350,723...119,462,882
Ensembl chr 8:119,350,724...119,462,614
JBrowse link
G Shbg sex hormone binding globulin affects binding ISO bifenthrin binds to SHBG protein CTD PMID:32278787 NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
increases expression
EXP
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bifenthrin analog results in increased expression of SOD1 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [bifenthrin analog results in increased expression of SOD1 protein]
bifenthrin analog results in increased expression of SOD1 mRNA; bifenthrin results in increased expression of SOD1 mRNA
CTD PMID:22718203 PMID:25149237 PMID:27916261 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression
EXP
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bifenthrin analog results in increased expression of SOD2 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [bifenthrin analog results in increased expression of SOD2 protein]
bifenthrin results in increased expression of SOD2 mRNA
CTD PMID:22718203 PMID:27916261 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase affects binding ISO bifenthrin binds to SRC protein CTD PMID:32278787 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 decreases expression ISO bifenthrin results in decreased expression of SRD5A2 mRNA CTD PMID:26071804 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions
decreases expression
EXP
ISO
bifenthrin analog inhibits the reaction [CGA results in increased expression of STAR mRNA]; bifenthrin inhibits the reaction [CGA protein results in increased expression of STAR mRNA]
bifenthrin results in decreased expression of STAR mRNA
CTD PMID:21251947 PMID:21871944 PMID:23994515 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 multiple interactions EXP bifenthrin inhibits the reaction [CGA protein results in increased expression of SULT1E1 mRNA] CTD PMID:21251947 NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275
JBrowse link
G Tff1 trefoil factor 1 increases expression ISO bifenthrin results in increased expression of TFF1 mRNA CTD PMID:20097460 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP bifenthrin inhibits the reaction [CGA protein results in increased expression of TGFB1 mRNA] CTD PMID:21251947 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
decreases expression
ISO
EXP
bifenthrin results in increased expression of TNF mRNA
bifenthrin results in increased expression of TNF protein
bifenthrin results in increased expression of TNF mRNA; bifenthrin results in increased expression of TNF protein
bifenthrin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF mRNA]
bifenthrin results in decreased expression of TNF mRNA
CTD PMID:23172818 PMID:26071804 PMID:27916261 PMID:28251819 PMID:29775722 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 increases expression
decreases expression
ISO bifenthrin results in increased expression of TRP53 mRNA
bifenthrin results in decreased expression of TRP53 mRNA
CTD PMID:20097460 PMID:26071804 PMID:27916261 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tspo translocator protein multiple interactions
decreases expression
EXP
ISO
bifenthrin analog inhibits the reaction [CGA results in increased expression of TSPO mRNA]
bifenthrin results in decreased expression of TSPO mRNA
CTD PMID:21871944 PMID:23994515 PMID:24449165 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450
JBrowse link
imiprothrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase decreases expression EXP imiprothrin results in decreased expression of CAT protein CTD PMID:33638779 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP imiprothrin results in increased expression of CYP1A2 mRNA CTD PMID:33638779 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression EXP imiprothrin results in increased expression of GPT protein CTD PMID:33638779 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Mt1 metallothionein 1 increases expression EXP imiprothrin results in increased expression of MT1 mRNA CTD PMID:33638779 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
JBrowse link
kadethrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO kadethrin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20057
    role 20023
      biological role 20010
        biochemical role 19662
          metabolite 19645
            eukaryotic metabolite 19348
              plant metabolite 17806
                chrysanthemic acid 241
                  cis-chrysanthemic acid 136
                    (+)-cis-chrysanthemic acid + 5
                    (-)-cis-chrysanthemic acid + 0
                    bifenthrin 132
Path 2
Term Annotations click to browse term
  CHEBI ontology 20057
    subatomic particle 20056
      composite particle 20068
        hadron 20056
          baryon 20056
            nucleon 20056
              atomic nucleus 20056
                atom 20056
                  main group element atom 19971
                    p-block element atom 19971
                      carbon group element atom 19889
                        carbon atom 19894
                          organic molecular entity 19882
                            organic group 18982
                              organic divalent group 18968
                                organodiyl group 18968
                                  carbonyl group 18923
                                    carbonyl compound 18923
                                      carboxylic acid 18620
                                        monocarboxylic acid 17854
                                          cyclopropanecarboxylic acid 1673
                                            chrysanthemic acid 241
                                              cis-chrysanthemic acid 136
                                                (+)-cis-chrysanthemic acid + 5
                                                (-)-cis-chrysanthemic acid + 0
                                                bifenthrin 132
paths to the root