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G |
Abca1 |
ATP binding cassette subfamily A member 1 |
multiple interactions increases expression increases phosphorylation increases degradation |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ABCA1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ABCA1 mRNA; Oleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; Oleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]] Oleic Acid results in increased expression of ABCA1 mRNA Oleic Acid results in increased phosphorylation of ABCA1 protein Oleic Acid results in increased degradation of ABCA1 protein Oleic Acid inhibits the reaction [27-hydroxycholesterol results in increased expression of ABCA1 mRNA] |
CTD |
PMID:16118212 PMID:18356535 PMID:30547786 |
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NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:67,681,297...67,801,170
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G |
Abcb11 |
ATP binding cassette subfamily B member 11 |
increases expression |
EXP |
Oleic Acid results in increased expression of ABCB11 mRNA |
CTD |
PMID:32738331 |
|
NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:54,017,127...54,112,730
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G |
Abcd3 |
ATP binding cassette subfamily D member 3 |
multiple interactions |
ISO |
PPARA protein promotes the reaction [Oleic Acid results in increased expression of ABCD3 mRNA] |
CTD |
PMID:18489776 |
|
NCBI chr 2:212,536,791...212,590,379
Ensembl chr 2:209,852,087...209,906,020
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G |
Abcg1 |
ATP binding cassette subfamily G member 1 |
decreases expression |
ISO |
Oleic Acid results in decreased expression of ABCG1 mRNA; Oleic Acid results in decreased expression of ABCG1 protein |
CTD |
PMID:16730733 |
|
NCBI chr20:9,128,056...9,184,312
Ensembl chr20:9,126,687...9,182,948
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G |
Abcg2 |
ATP binding cassette subfamily G member 2 |
increases expression |
ISO |
Oleic Acid results in increased expression of ABCG2 mRNA |
CTD |
PMID:22819932 |
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NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:87,745,319...87,802,409
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G |
Acaa1a |
acetyl-CoA acyltransferase 1A |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of ACAA1 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACAA1 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 8:127,956,126...127,966,348
Ensembl chr 8:119,079,775...119,088,624
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G |
Acaa2 |
acetyl-CoA acyltransferase 2 |
multiple interactions increases expression |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACAA2 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACAA2 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACAA2 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACAA2 mRNA Oleic Acid results in increased expression of ACAA2 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr18:70,620,310...70,648,417
Ensembl chr18:68,345,012...68,373,249
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G |
Acaca |
acetyl-CoA carboxylase alpha |
multiple interactions increases expression |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of ACACA mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACACA mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ACACA mRNA; cyhalothrin promotes the reaction [Oleic Acid results in increased expression of ACACA protein]; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of ACACA mRNA] |
CTD |
PMID:30611723 PMID:36529352 PMID:36905866 |
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NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,014,170...69,276,457
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G |
Acacb |
acetyl-CoA carboxylase beta |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of ACACB mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACACB mRNA |
CTD |
PMID:30611723 |
|
NCBI chr12:48,026,394...48,138,214
Ensembl chr12:42,366,548...42,457,655
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G |
Acad9 |
acyl-CoA dehydrogenase family, member 9 |
multiple interactions increases expression |
ISO |
[Vehicle Emissions results in increased abundance of Particulate Matter] inhibits the reaction [Oleic Acid results in increased expression of ACAD9 mRNA] |
CTD |
PMID:31340670 |
|
NCBI chr 2:120,871,329...120,894,306
Ensembl chr 2:118,943,174...118,966,547
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G |
Acadl |
acyl-CoA dehydrogenase, long chain |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ACADL mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of ACADL mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 9:75,783,689...75,822,077
Ensembl chr 9:68,333,980...68,372,220
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G |
Acadm |
acyl-CoA dehydrogenase medium chain |
multiple interactions |
EXP ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of ACADM mRNA; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of ACADM mRNA]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of ACADM mRNA] [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACADM mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACADM mRNA |
CTD |
PMID:26190035 PMID:30611723 |
|
NCBI chr 2:245,518,693...245,542,864
Ensembl chr 2:242,858,865...242,883,147
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G |
Acads |
acyl-CoA dehydrogenase short chain |
multiple interactions increases expression |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACADS mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACADS mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACADS mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACADS mRNA Oleic Acid results in increased expression of ACADS mRNA |
CTD |
PMID:30611723 |
|
NCBI chr12:47,154,259...47,163,580
Ensembl chr12:41,493,626...41,502,898
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G |
Acadvl |
acyl-CoA dehydrogenase, very long chain |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ACADVL mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACADVL mRNA |
CTD |
PMID:30611723 |
|
NCBI chr10:55,231,558...55,236,786
Ensembl chr10:54,732,469...54,738,075
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G |
Acat1 |
acetyl-CoA acetyltransferase 1 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACAT1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACAT1 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 8:62,876,003...62,905,080
Ensembl chr 8:53,979,813...54,008,855
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G |
Acat2 |
acetyl-CoA acetyltransferase 2 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACAT2 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACAT2 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 1:50,100,840...50,118,886
Ensembl chr 1:47,695,788...47,752,821
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G |
Ace |
angiotensin I converting enzyme |
affects activity |
EXP |
Oleic Acid affects the activity of ACE protein |
CTD |
PMID:20804650 |
|
NCBI chr10:91,410,129...91,430,246
Ensembl chr10:90,910,316...90,931,131
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G |
Acly |
ATP citrate lyase |
multiple interactions decreases expression |
ISO |
[[Vehicle Emissions results in increased abundance of Particulate Matter] which co-treated with Oleic Acid] results in decreased expression of ACLY mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACLY mRNA Oleic Acid results in decreased expression of ACLY mRNA |
CTD |
PMID:30611723 PMID:31340670 |
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NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,412,049...85,463,320
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G |
Acot1 |
acyl-CoA thioesterase 1 |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of ACOT1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT1 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 6:109,367,274...109,375,268
Ensembl chr 6:103,636,041...103,644,163
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G |
Acot12 |
acyl-CoA thioesterase 12 |
multiple interactions increases expression |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACOT12 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACOT12 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT12 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACOT12 mRNA Oleic Acid results in increased expression of ACOT12 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 2:24,721,648...24,763,686
Ensembl chr 2:22,986,626...23,027,536
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G |
Acot4 |
acyl-CoA thioesterase 4 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACOT4 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT4 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACOT4 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 6:109,399,032...109,405,138
Ensembl chr 6:103,668,753...103,673,917
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G |
Acot6 |
acyl-CoA thioesterase 6 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACOT6 mRNA; [Farnesol analog co-treated with Oleic Acid] results in decreased expression of ACOT6 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT6 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 6:109,463,513...109,472,587
Ensembl chr 6:103,732,372...103,741,446
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G |
Acot7 |
acyl-CoA thioesterase 7 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACOT7 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT7 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 5:167,969,284...168,062,033
Ensembl chr 5:162,684,645...162,779,309
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G |
Acot8 |
acyl-CoA thioesterase 8 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of ACOT8 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT8 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 3:173,950,530...173,962,188
Ensembl chr 3:153,531,193...153,542,851
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G |
Acox1 |
acyl-CoA oxidase 1 |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; [Fenofibrate co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOX1 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; [muraglitazar co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of ACOX1 mRNA; [Rosiglitazone co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; [tesaglitazar co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of ACOX1 mRNA] |
CTD |
PMID:24534255 PMID:30611723 PMID:36905866 |
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NCBI chr10:101,905,083...101,930,136
Ensembl chr10:101,406,197...101,431,232
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G |
Acox2 |
acyl-CoA oxidase 2 |
multiple interactions decreases expression |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOX2 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of ACOX2 mRNA Oleic Acid results in decreased expression of ACOX2 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr15:19,090,820...19,122,392
Ensembl chr15:16,660,272...16,692,160
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G |
Acsl1 |
acyl-CoA synthetase long-chain family member 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ACSL1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ACSL1 mRNA |
CTD |
PMID:30547786 |
|
NCBI chr16:52,487,870...52,554,110
Ensembl chr16:45,755,254...45,821,541
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G |
Acsl3 |
acyl-CoA synthetase long-chain family member 3 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ACSL3 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 9:87,563,601...87,613,078
Ensembl chr 9:80,115,112...80,164,627
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G |
Acsl4 |
acyl-CoA synthetase long-chain family member 4 |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of ACSL4 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACSL4 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACSL4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ACSL4 mRNA |
CTD |
PMID:30547786 PMID:30611723 |
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NCBI chr X:110,739,633...110,803,416
Ensembl chr X:105,942,799...106,006,427
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G |
Acsl5 |
acyl-CoA synthetase long-chain family member 5 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACSL5 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACSL5 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACSL5 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 1:264,294,851...264,341,943
Ensembl chr 1:254,292,521...254,336,607
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G |
Acta2 |
actin alpha 2, smooth muscle |
multiple interactions increases expression |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of ACTA2 mRNA Oleic Acid results in increased expression of ACTA2 mRNA |
CTD |
PMID:26187275 PMID:32918399 |
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NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:231,746,548...231,759,554
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G |
Adam17 |
ADAM metallopeptidase domain 17 |
multiple interactions |
ISO |
[[Palmitic Acid co-treated with Oleic Acid] results in increased abundance of Fatty Acids, Nonesterified] which results in increased expression of ADAM17 mRNA; lactucin inhibits the reaction [[[Palmitic Acid co-treated with Oleic Acid] results in increased abundance of Fatty Acids, Nonesterified] which results in increased expression of ADAM17 mRNA] |
CTD |
PMID:36055749 |
|
NCBI chr 6:46,601,583...46,663,690
Ensembl chr 6:40,872,856...40,920,639
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
decreases expression multiple interactions |
EXP |
Oleic Acid results in decreased expression of ADIPOQ mRNA sophocarpine inhibits the reaction [Oleic Acid results in decreased expression of ADIPOQ mRNA] |
CTD |
PMID:23395669 |
|
NCBI chr11:91,226,524...91,240,244
Ensembl chr11:77,721,912...77,735,564
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G |
Adipor2 |
adiponectin receptor 2 |
decreases expression |
EXP |
oleic acid cotreated with ethanol decreases expression of adipor2 mRNA in rat primary hepatocytes |
RGD |
PMID:21194380 |
RGD:24922202 |
NCBI chr 4:154,195,440...154,261,141
Ensembl chr 4:152,524,623...152,559,355
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G |
Agpat1 |
1-acylglycerol-3-phosphate O-acyltransferase 1 |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in decreased expression of AGPAT1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of AGPAT1 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr20:4,140,565...4,149,531
Ensembl chr20:4,135,957...4,145,278
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G |
Agpat2 |
1-acylglycerol-3-phosphate O-acyltransferase 2 |
increases expression multiple interactions |
ISO |
Oleic Acid results in increased expression of AGPAT2 mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of AGPAT2 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of AGPAT2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AGPAT2 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of AGPAT2 mRNA |
CTD |
PMID:30547786 PMID:30611723 |
|
NCBI chr 3:29,814,924...29,826,569
Ensembl chr 3:9,416,843...9,428,371
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G |
Agpat5 |
1-acylglycerol-3-phosphate O-acyltransferase 5 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AGPAT5 mRNA |
CTD |
PMID:30547786 |
|
NCBI chr16:77,641,887...77,688,148
Ensembl chr16:70,943,135...70,985,560
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G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AHR mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of AHR mRNA; Oleic Acid inhibits the reaction [Particulate Matter affects the localization of AHR protein] |
CTD |
PMID:30547786 PMID:38456238 |
|
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions increases phosphorylation decreases phosphorylation |
EXP ISO |
Oleic Acid inhibits the reaction [IRS2 results in increased phosphorylation of and results in increased activity of AKT1 protein] Oleic acid increases phosphorylation of AKT1 protein in hepatocellular carcinoma cells [Oleic Acid co-treated with Palmitic Acid] results in decreased phosphorylation of AKT1 protein 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [NAD inhibits the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein]]; [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride co-treated with NAD] inhibits the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein]; NAD inhibits the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein]; PARP1 protein affects the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein] |
CTD RGD |
PMID:14604813 PMID:25536389 PMID:26847930 PMID:37460115 |
RGD:408364960 |
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921
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G |
Alb |
albumin |
multiple interactions affects binding decreases secretion |
ISO |
[ALB protein binds to Oleic Acid] promotes the reaction [ALB protein results in increased reduction of Dithionitrobenzoic Acid]; [ALB protein binds to Oleic Acid] promotes the reaction [Pyruvaldehyde results in increased oxidation of ALB protein]; [ALB protein modified form binds to Oleic Acid] which results in decreased reduction of Dithionitrobenzoic Acid; [Oleic Acid co-treated with muraglitazar] results in increased expression of ALB mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of ALB protein; [Oleic Acid co-treated with Rosiglitazone] results in increased expression of ALB mRNA; [Oleic Acid co-treated with tesaglitazar] results in increased expression of ALB mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of ALB protein]; Quercetin inhibits the reaction [Oleic Acid results in decreased secretion of ALB protein]; Silymarin inhibits the reaction [Oleic Acid results in decreased secretion of ALB protein]; Vitamin E inhibits the reaction [Oleic Acid results in decreased secretion of ALB protein] |
CTD |
PMID:23348005 PMID:24534255 PMID:25451573 PMID:38103844 |
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NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,607,381...17,622,836
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G |
Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
decreases expression |
ISO |
Oleic Acid results in decreased expression of ALDH1A1 mRNA |
CTD |
PMID:26739624 |
|
NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:218,042,127...218,152,961
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|
G |
Angptl4 |
angiopoietin-like 4 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ANGPTL4 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ANGPTL4 mRNA |
CTD |
PMID:30547786 |
|
NCBI chr 7:15,252,450...15,259,971
Ensembl chr 7:14,550,311...14,556,519
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G |
Anxa2 |
annexin A2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ANXA2 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ANXA2 mRNA |
CTD |
PMID:30547786 |
|
NCBI chr 8:78,986,252...79,022,638
Ensembl chr 8:70,105,253...70,141,658
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|
G |
Apoa1 |
apolipoprotein A1 |
multiple interactions |
ISO |
Oleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; Oleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]] |
CTD |
PMID:16118212 |
|
NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:46,527,144...46,529,035
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|
G |
Apoa4 |
apolipoprotein A4 |
increases expression |
ISO |
Oleic Acid results in increased expression of APOA4 mRNA |
CTD |
PMID:26739624 |
|
NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:46,539,082...46,541,469
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G |
Apoa5 |
apolipoprotein A5 |
increases expression multiple interactions |
ISO |
Oleic Acid results in increased expression of APOA5 mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of APOA5 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of APOA5 mRNA; [GW 4064 co-treated with Oleic Acid] results in increased expression of APOA5 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of APOA5 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 8:55,446,329...55,460,509
Ensembl chr 8:46,561,229...46,563,816
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G |
Apob |
apolipoprotein B |
multiple interactions decreases expression increases expression |
ISO EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of APOB mRNA; [Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Oleic Acid co-treated with Folic Acid co-treated with Vitamin B 6 co-treated with Vitamin E] results in decreased expression of APOB protein; [GW 4064 co-treated with Oleic Acid] results in decreased expression of APOB mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of APOB mRNA; Bezafibrate inhibits the reaction [Oleic Acid results in increased expression of APOB protein]; Oleic Acid inhibits the reaction [Glucosamine results in decreased secretion of APOB protein]; Oleic Acid results in increased expression of and results in increased secretion of APOB protein Oleic Acid results in decreased expression of APOB mRNA [Oleic Acid co-treated with Palmitic Acid] results in increased expression of APOB mRNA; Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of APOB mRNA]; Oleic Acid inhibits the reaction [Glucosamine results in increased degradation of APOB protein] |
CTD |
PMID:12048068 PMID:15618547 PMID:17237316 PMID:19383982 PMID:26854922 PMID:30611723 PMID:32918399 More...
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NCBI chr 6:36,563,704...36,603,300
Ensembl chr 6:30,844,368...30,892,497
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G |
Apoc3 |
apolipoprotein C3 |
multiple interactions |
ISO |
[Oleic Acid co-treated with muraglitazar] results in increased expression of APOC3 mRNA; [Oleic Acid co-treated with rosiglitazone] results in increased expression of APOC3 mRNA; [Oleic Acid co-treated with tesaglitazar] results in increased expression of APOC3 mRNA |
CTD |
PMID:24534255 |
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NCBI chr 8:55,428,172...55,430,352
Ensembl chr 8:46,531,478...46,533,583
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G |
Apoc4 |
apolipoprotein C4 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of APOC4 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of APOC4 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of APOC4 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 1:88,463,713...88,467,909
Ensembl chr 1:79,335,745...79,339,981
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G |
Apoe |
apolipoprotein E |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of APOE mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of APOE mRNA |
CTD |
PMID:30611723 |
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NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:79,353,916...79,357,932
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G |
App |
amyloid beta precursor protein |
multiple interactions |
ISO |
[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Oleic Acid; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Oleic Acid] |
CTD |
PMID:39172838 |
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NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561
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G |
Arg1 |
arginase 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ARG1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ARG1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:20,475,968...20,488,422
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G |
Atf6 |
activating transcription factor 6 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of ATF6 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ATF6 mRNA Oleic Acid inhibits the reaction [[Palmitates co-treated with bisphenol A] results in increased expression of ATF6 mRNA] |
CTD |
PMID:32369900 PMID:32976987 |
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NCBI chr13:85,460,312...85,639,959
Ensembl chr13:82,930,034...83,107,177
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G |
Atg5 |
autophagy related 5 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of ATG5 protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of ATG5 protein] |
CTD |
PMID:36905866 |
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NCBI chr20:49,380,835...49,471,826
Ensembl chr20:47,798,290...47,889,209
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G |
Atg7 |
autophagy related 7 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of ATG7 protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of ATG7 protein] |
CTD |
PMID:36905866 |
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NCBI chr 4:149,390,000...149,597,534
Ensembl chr 4:147,718,752...147,925,593
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G |
B4galt5 |
beta-1,4-galactosyltransferase 5 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of B4GALT5 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of B4GALT5 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 3:176,437,073...176,453,001
Ensembl chr 3:156,018,053...156,070,074
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G |
Bace1 |
beta-secretase 1 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of BACE1 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of BACE1 protein; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein]]; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein]]; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein]]; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 protein]]; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of BACE1 protein]]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of BACE1 protein] |
CTD |
PMID:37009739 |
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NCBI chr 8:55,038,842...55,061,138
Ensembl chr 8:46,142,116...46,165,876
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of BAX mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of BAX mRNA |
CTD |
PMID:32369900 |
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NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of BCL2 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of BCL2 mRNA |
CTD |
PMID:32369900 |
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NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Casp3 |
caspase 3 |
multiple interactions increases cleavage |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of CASP3 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CASP3 mRNA Oleic Acid results in increased cleavage of CASP3 protein Oleic Acid inhibits the reaction [[Palmitates co-treated with bisphenol A] results in increased cleavage of CASP3 protein] |
CTD |
PMID:32369900 PMID:32976987 PMID:36273635 |
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NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
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G |
Casp9 |
caspase 9 |
multiple interactions increases cleavage |
EXP ISO |
IRS2 inhibits the reaction [Oleic Acid results in increased cleavage of CASP9 protein] 3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of CASP9 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CASP9 mRNA |
CTD |
PMID:14604813 PMID:32369900 |
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Ensembl chr 5:154,109,046...154,126,626
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G |
Cat |
catalase |
multiple interactions increases activity decreases activity |
ISO EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CAT mRNA; Quercetin inhibits the reaction [Oleic Acid results in decreased activity of CAT protein]; Silymarin inhibits the reaction [Oleic Acid results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Oleic Acid results in decreased activity of CAT protein] Oleic Acid results in increased activity of CAT protein [Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in increased activity of CAT protein; [Oleic Acid co-treated with Palmitic Acid] results in increased activity of CAT protein; Dexamethasone inhibits the reaction [Oleic Acid results in increased activity of CAT protein]; gossypin inhibits the reaction [Oleic Acid results in increased activity of CAT protein] |
CTD |
PMID:23348005 PMID:26854922 PMID:30547786 PMID:37696682 |
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NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
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G |
Cav2 |
caveolin 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of CAV2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 4:46,582,681...46,590,058
Ensembl chr 4:45,616,712...45,624,244
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G |
Cd36 |
CD36 molecule |
multiple interactions increases expression |
ISO EXP |
GW 4064 inhibits the reaction [Oleic Acid results in increased expression of CD36 protein] Oleic Acid results in increased expression of CD36 mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of CD36 mRNA; [GW 4064 co-treated with Oleic Acid] results in increased expression of CD36 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of CD36 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CD36 mRNA; [Tamoxifen co-treated with Oleic Acid] results in increased expression of CD36 mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CD36 mRNA]; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CD36 mRNA] [Oleic Acid co-treated with Linoleic Acid] results in increased expression of CD36 mRNA |
CTD |
PMID:23371517 PMID:28552552 PMID:30611723 PMID:36347319 PMID:38092172 PMID:38103844 PMID:38191086 More...
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NCBI chr 4:18,209,088...18,302,142
Ensembl chr 4:17,354,466...17,513,903
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of CDKN1A mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CDKN1A mRNA |
CTD |
PMID:32369900 |
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NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585
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G |
Cidec |
cell death-inducing DFFA-like effector c |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CIDEC protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CIDEC mRNA |
CTD |
PMID:30547786 |
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NCBI chr 4:148,124,924...148,137,806
Ensembl chr 4:146,569,289...146,582,173
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G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions increases expression |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of COL1A1 mRNA; Sorafenib inhibits the reaction [Oleic Acid results in increased expression of COL1A1 mRNA] |
CTD |
PMID:26187275 PMID:32918399 |
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NCBI chr10:80,380,458...80,397,461
Ensembl chr10:79,883,622...79,900,624
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G |
Cox10 |
cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of COX10 mRNA |
CTD |
PMID:30611723 |
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NCBI chr10:49,130,209...49,242,009
Ensembl chr10:48,630,676...48,746,667
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G |
Cpt1a |
carnitine palmitoyltransferase 1A |
increases expression decreases expression multiple interactions |
EXP ISO |
Oleic Acid results in increased expression of CPT1A mRNA Oleic Acid results in decreased expression of CPT1A mRNA [Starch co-treated with Oleic Acid] results in increased expression of CPT1A mRNA; [Sucrose co-treated with Oleic Acid] results in increased expression of CPT1A mRNA [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of CPT1A mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A protein; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of CPT1A mRNA]; Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A protein]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of CPT1A mRNA]; tetrabromobisphenol A promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA]; Triiodothyronine promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA] [Farnesol analog co-treated with Oleic Acid] results in increased expression of CPT1A mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of CPT1A mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of CPT1A mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in decreased expression of CPT1A protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CPT1A mRNA; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of CPT1A protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CPT1A mRNA; Bezafibrate promotes the reaction [Oleic Acid results in increased expression of CPT1A mRNA]; Fenofibrate promotes the reaction [Oleic Acid results in increased expression of CPT1A mRNA]; isosilybin promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA]; muraglitazar promotes the reaction [Oleic Acid results in increased expression of CPT1A mRNA]; Rosiglitazone promotes the reaction [Oleic Acid results in increased expression of CPT1A mRNA]; Sorafenib inhibits the reaction [Oleic Acid results in decreased expression of CPT1A mRNA]; tesaglitazar promotes the reaction [Oleic Acid results in increased expression of CPT1A mRNA] |
CTD |
PMID:11171094 PMID:24534255 PMID:25048947 PMID:26190035 PMID:26854922 PMID:26895660 PMID:30547786 PMID:30611723 PMID:32918399 PMID:36347319 More...
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NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:200,565,613...200,627,055
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G |
Cpt2 |
carnitine palmitoyltransferase 2 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of CPT2 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of CPT2 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of CPT2 mRNA; [muraglitazar co-treated with Oleic Acid] results in increased expression of CPT2 mRNA; [Oleic Acid co-treated with Bezafibrate] results in increased expression of CPT2 mRNA; [Oleic Acid co-treated with Fenofibrate] results in increased expression of CPT2 mRNA; [Oleic Acid co-treated with tesaglitazar] results in increased expression of CPT2 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of CPT2 mRNA; [Rosiglitazone co-treated with Oleic Acid] results in increased expression of CPT2 mRNA; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of CPT2 mRNA] |
CTD |
PMID:24534255 PMID:30611723 PMID:36905866 |
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NCBI chr 5:127,893,450...127,911,347
Ensembl chr 5:122,664,677...122,682,095
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G |
Crebbp |
CREB binding protein |
decreases expression |
EXP |
Oleic Acid results in decreased expression of CREBBP mRNA |
CTD |
PMID:24349266 |
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NCBI chr10:11,842,307...11,968,266
Ensembl chr10:11,335,953...11,461,888
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G |
Crp |
C-reactive protein |
multiple interactions |
ISO |
[Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Oleic Acid co-treated with Folic Acid co-treated with Vitamin B 6 co-treated with Vitamin E] results in decreased expression of CRP protein |
CTD |
PMID:17237316 |
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NCBI chr13:87,694,062...87,695,978
Ensembl chr13:85,124,977...85,175,178
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of CXCL10 mRNA |
CTD |
PMID:30547786 |
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NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,704,758...15,706,975
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CXCL2 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of CXCL2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,181,062...17,183,075
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G |
Cycs |
cytochrome c, somatic |
multiple interactions |
ISO |
[Oleic Acid co-treated with anastrozole] affects the localization of CYCS protein; [Oleic Acid co-treated with letrozole] affects the localization of CYCS protein; [Oleic Acid co-treated with Linoleic Acid] results in increased expression of CYCS protein |
CTD |
PMID:24161488 PMID:27016407 |
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NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
increases expression multiple interactions |
ISO |
Oleic Acid results in increased expression of CYP1A1 mRNA; Oleic Acid results in increased expression of CYP1A1 protein [Estradiol co-treated with Benzo(a)pyrene] promotes the reaction [Oleic Acid results in increased expression of CYP1A1 mRNA]; [Estradiol co-treated with Benzo(a)pyrene] promotes the reaction [Oleic Acid results in increased expression of CYP1A1 protein]; Oleic Acid inhibits the reaction [Particulate Matter results in increased expression of CYP1A1 mRNA]; Oleic Acid inhibits the reaction [Particulate Matter results in increased expression of CYP1A1 protein] |
CTD |
PMID:31730885 PMID:38456238 |
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NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
decreases expression multiple interactions |
ISO |
Oleic Acid results in decreased expression of CYP1A2 mRNA Farnesol analog inhibits the reaction [Oleic Acid results in decreased expression of CYP1A2 mRNA] |
CTD |
PMID:30611723 |
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NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:58,075,367...58,082,312
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G |
Cyp24a1 |
cytochrome P450, family 24, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CYP24A1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CYP24A1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 3:179,694,647...179,709,083
Ensembl chr 3:159,275,947...159,290,383
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G |
Cyp26a1 |
cytochrome P450, family 26, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CYP26A1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CYP26A1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 1:244,883,822...244,887,657
Ensembl chr 1:235,471,298...235,475,204
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G |
Cyp26b1 |
cytochrome P450, family 26, subfamily b, polypeptide 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in increased expression of CYP26B1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 4:118,599,356...118,616,176
Ensembl chr 4:117,041,808...117,058,628
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G |
Cyp2b3 |
cytochrome P450, family 2, subfamily b, polypeptide 3 |
multiple interactions decreases expression |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of CYP2B6 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of CYP2B6 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of CYP2B6 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of CYP2B6 mRNA; [Oleic Acid co-treated with Rosiglitazone] results in increased expression of CYP2B6 mRNA; [Oleic Acid co-treated with Troglitazone] results in increased expression of CYP2B6 mRNA; Farnesol analog inhibits the reaction [Oleic Acid results in decreased expression of CYP2B6 mRNA] |
CTD |
PMID:24534255 PMID:30611723 |
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NCBI chr 1:90,780,468...90,859,852
Ensembl chr 1:81,652,787...81,732,143
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions increases expression |
EXP ISO |
[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of CYP2E1 mRNA]; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CYP2E1 mRNA; Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CYP2E1 mRNA] Oleic Acid results in increased expression of CYP2E1 mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of CYP2E1 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of CYP2E1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of CYP2E1 mRNA; Farnesol analog inhibits the reaction [Oleic Acid results in increased expression of CYP2E1 mRNA] |
CTD |
PMID:26854922 PMID:30611723 |
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NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
multiple interactions decreases expression |
ISO |
Farnesol analog inhibits the reaction [Oleic Acid results in decreased expression of CYP3A4 mRNA] Oleic Acid results in decreased expression of CYP3A4 mRNA; Oleic Acid results in decreased expression of CYP3A4 protein |
CTD |
PMID:26739624 PMID:30611723 |
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NCBI chr12:14,321,771...14,343,886
Ensembl chr12:9,015,383...9,285,008
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G |
Cyp4a1 |
cytochrome P450, family 4, subfamily a, polypeptide 1 |
multiple interactions |
EXP |
[Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in decreased expression of CYP4A1 mRNA |
CTD |
PMID:26854922 |
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NCBI chr 5:134,360,096...134,374,233
Ensembl chr 5:129,123,336...129,137,464
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G |
Cyp4f6 |
cytochrome P450, family 4, subfamily f, polypeptide 6 |
multiple interactions |
ISO |
PPARA protein promotes the reaction [Oleic Acid results in increased expression of CYP4F16 mRNA] |
CTD |
PMID:18489776 |
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NCBI chr 7:12,680,799...12,708,378
Ensembl chr 7:12,030,301...12,057,782
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G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
decreases expression multiple interactions |
EXP ISO |
Oleic Acid results in decreased expression of CYP7A1 mRNA [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CYP7A1 mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CYP7A1 mRNA] |
CTD |
PMID:32738331 PMID:38103844 |
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NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:19,376,974...19,386,688
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of DDIT3 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of DDIT3 mRNA [Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein]]; Oleic Acid inhibits the reaction [[Palmitates co-treated with bisphenol A] results in increased expression of DDIT3 mRNA]; Oleic Acid inhibits the reaction [[Palmitates co-treated with bisphenol A] results in increased expression of DDIT3 protein]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein] |
CTD |
PMID:32369900 PMID:32976987 PMID:37009739 |
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NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201
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G |
Decr1 |
2,4-dienoyl-CoA reductase 1 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of DECR1 mRNA; [Farnesol analog co-treated with Oleic Acid] results in decreased expression of DECR1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of DECR1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 5:34,208,195...34,236,074
Ensembl chr 5:29,411,172...29,439,018
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G |
Derl1 |
derlin 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of DERL1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 7:91,293,963...91,316,639
Ensembl chr 7:89,404,417...89,427,145
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G |
Dgat1 |
diacylglycerol O-acyltransferase 1 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of DGAT1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:108,218,524...108,234,299
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G |
Dgat2 |
diacylglycerol O-acyltransferase 2 |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of DGAT2 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of DGAT2 mRNA; [Oleic Acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of DGAT2 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of DGAT2 mRNA |
CTD |
PMID:30611723 PMID:38092172 |
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NCBI chr 1:162,866,237...162,896,655
Ensembl chr 1:153,454,080...153,484,428
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G |
Dhdds |
dehydrodolichyl diphosphate synthase subunit |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of DHDDS mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of DHDDS mRNA |
CTD |
PMID:30611723 |
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NCBI chr 5:151,482,139...151,508,248
Ensembl chr 5:146,197,457...146,224,454
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G |
Dnm1l |
dynamin 1-like |
affects phosphorylation |
ISO |
Oleic Acid affects the phosphorylation of DNM1L protein |
CTD |
PMID:36273635 |
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NCBI chr11:98,084,049...98,135,663
Ensembl chr11:84,581,216...84,631,482
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G |
Dst |
dystonin |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in decreased expression of DST mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of DST mRNA |
CTD |
PMID:30547786 |
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NCBI chr 9:43,631,716...44,025,535
Ensembl chr 9:36,135,284...36,529,615
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G |
Dync1h1 |
dynein cytoplasmic 1 heavy chain 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of DYNC1H1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of DYNC1H1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 6:135,436,375...135,502,117
Ensembl chr 6:129,609,397...129,680,883
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G |
Dync1i1 |
dynein cytoplasmic 1 intermediate chain 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of DYNC1I1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of DYNC1I1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 4:34,819,313...35,132,647
Ensembl chr 4:33,852,927...34,166,149
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G |
E2f1 |
E2F transcription factor 1 |
decreases expression |
ISO |
Oleic Acid results in decreased expression of E2F1 protein |
CTD |
PMID:16027227 |
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NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:143,049,478...143,075,361
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G |
Ech1 |
enoyl-CoA hydratase 1 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ECH1 mRNA; [Oleic Acid co-treated with muraglitazar] results in increased expression of ECH1 mRNA; [Oleic Acid co-treated with Rosiglitazone] results in increased expression of ECH1 mRNA; [Oleic Acid co-treated with tesaglitazar] results in increased expression of ECH1 mRNA; [Oleic Acid co-treated with Troglitazone] results in increased expression of ECH1 mRNA |
CTD |
PMID:24534255 PMID:30611723 |
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NCBI chr 1:93,241,076...93,248,314
Ensembl chr 1:84,112,751...84,120,795
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G |
Echs1 |
enoyl-CoA hydratase, short chain 1 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ECHS1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:194,895,036...194,903,884
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G |
Edn1 |
endothelin 1 |
decreases expression |
ISO |
Oleic Acid results in decreased expression of EDN1 mRNA; Oleic Acid results in decreased expression of EDN1 protein |
CTD |
PMID:16895544 |
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NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,454,420...22,460,885
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions increases phosphorylation |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of EGFR protein; [Palmitic Acid co-treated with Oleic Acid] affects the expression of EGFR mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of EGFR protein] Oleic Acid results in increased phosphorylation of EGFR protein |
CTD |
PMID:27447558 PMID:30547786 PMID:38103844 |
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NCBI chr14:95,378,626...95,551,358
Ensembl chr14:91,177,067...91,344,382
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G |
Ehhadh |
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of EHHADH mRNA |
CTD |
PMID:30611723 |
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NCBI chr11:92,746,409...92,779,647
Ensembl chr11:79,241,938...79,275,188
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G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of EIF2AK3 mRNA]; [Palmitic Acid co-treated with Oleic Acid] affects the expression of EIF2AK3 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of EIF2AK3 mRNA |
CTD |
PMID:30547786 PMID:32369900 |
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NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:102,805,510...102,866,911
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G |
Elovl5 |
ELOVL fatty acid elongase 5 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ELOVL5 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 8:87,671,164...87,737,618
Ensembl chr 8:78,790,846...78,857,284
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G |
Elovl6 |
ELOVL fatty acid elongase 6 |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of ELOVL6 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ELOVL6 mRNA; [Oleic Acid co-treated with Bezafibrate] results in increased expression of ELOVL6 mRNA; [Oleic Acid co-treated with Fenofibrate] affects the expression of ELOVL6 mRNA; [Oleic Acid co-treated with Rosiglitazone] results in increased expression of ELOVL6 mRNA; [Oleic Acid co-treated with tesaglitazar] results in increased expression of ELOVL6 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ELOVL6 mRNA |
CTD |
PMID:24534255 PMID:30547786 PMID:30611723 |
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NCBI chr 2:220,738,095...220,845,528
Ensembl chr 2:218,063,804...218,171,186
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G |
Eno3 |
enolase 3 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ENO3 mRNA |
CTD |
PMID:30547786 |
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NCBI chr10:55,868,880...55,876,099
Ensembl chr10:55,366,975...55,375,921
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G |
Erlin1 |
ER lipid raft associated 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ERLIN1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 1:252,870,356...252,905,681
Ensembl chr 1:242,921,152...242,956,394
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G |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of ERN1 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ERN1 mRNA |
CTD |
PMID:32369900 |
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NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,330,654...91,421,029
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G |
Fabp1 |
fatty acid binding protein 1 |
affects binding multiple interactions decreases expression |
EXP ISO |
Oleic Acid binds to FABP1 protein Oleic acid binds to Fabp1 protein [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of FABP1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of FABP1 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of FABP1 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of FABP1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of FABP1 mRNA; Dibutyl Phthalate inhibits the reaction [Oleic Acid results in decreased expression of FABP1 mRNA]; Diethylhexyl Phthalate inhibits the reaction [Oleic Acid results in decreased expression of FABP1 mRNA]; Oleic Acid inhibits the reaction [11-(dansylamino)undecanoic acid binds to FABP1 protein] Bezafibrate inhibits the reaction [Oleic Acid binds to FABP1 protein] |
CTD RGD |
PMID:2328261 PMID:30547786 PMID:30611723 PMID:31110286 PMID:38092172 PMID:1939124 More...
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RGD:1626448 |
NCBI chr 4:104,744,302...104,753,119
Ensembl chr 4:103,191,006...103,194,788
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G |
Fabp2 |
fatty acid binding protein 2 |
affects binding |
EXP |
FABP2 protein modified form binds to Oleic Acid |
CTD |
PMID:16137630 |
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NCBI chr 2:213,724,629...213,728,686
Ensembl chr 2:211,040,032...211,044,089
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G |
Fabp4 |
fatty acid binding protein 4 |
multiple interactions affects localization increases expression |
ISO |
[Glucose deficiency co-treated with Clofibrate co-treated with Oleic Acid] results in increased expression of FABP4 mRNA; [Glucose deficiency co-treated with Oleic Acid] results in increased expression of FABP4 mRNA Oleic Acid analog affects the localization of FABP4 protein Oleic Acid results in increased expression of FABP4 mRNA |
CTD |
PMID:8536680 PMID:26739624 PMID:27939595 |
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NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:91,580,885...91,585,578
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G |
Fas |
Fas cell surface death receptor |
multiple interactions increases expression |
EXP ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of FAS mRNA; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of FAS mRNA] [Oleic Acid co-treated with Palmitic Acid] results in increased expression of FAS protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of FAS mRNA; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of FAS protein] Oleic Acid results in increased expression of FAS mRNA |
CTD |
PMID:26190035 PMID:32918399 PMID:36347319 PMID:36905866 |
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NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591
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G |
Fasn |
fatty acid synthase |
multiple interactions |
ISO EXP |
[cyhalothrin co-treated with Oleic Acid] results in increased expression of FASN protein; [Farnesol analog co-treated with Oleic Acid] results in increased expression of FASN mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of FASN mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of FASN mRNA; [Oleic Acid co-treated with Bezafibrate] results in increased expression of FASN mRNA; [Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of FASN protein; [Oleic Acid co-treated with Fenofibrate] affects the expression of FASN mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of FASN mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of FASN mRNA]; GW 6471 inhibits the reaction [[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of FASN protein]; Metformin inhibits the reaction [[cyhalothrin co-treated with Oleic Acid] results in increased expression of FASN protein] [Sucrose co-treated with Oleic Acid] results in increased expression of FASN mRNA [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of FASN mRNA]; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of FASN mRNA |
CTD |
PMID:24534255 PMID:26854922 PMID:26895660 PMID:30611723 PMID:33508418 PMID:36529352 PMID:38103844 More...
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NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261
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G |
Fdft1 |
farnesyl diphosphate farnesyl transferase 1 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of FDFT1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of FDFT1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr15:41,588,114...41,616,168
Ensembl chr15:37,412,146...37,440,287
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G |
Fdps |
farnesyl diphosphate synthase |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of FDPS mRNA |
CTD |
PMID:30611723 |
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NCBI chr 2:176,795,192...176,804,816
Ensembl chr 2:174,486,665...174,507,776
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G |
Ffar1 |
free fatty acid receptor 1 |
decreases expression |
EXP |
Oleic Acid results in decreased expression of FFAR1 mRNA |
CTD |
PMID:24349266 |
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NCBI chr 1:95,238,785...95,239,689
Ensembl chr 1:86,111,368...86,112,272
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G |
Fgf21 |
fibroblast growth factor 21 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of FGF21 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of FGF21 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 1:105,219,825...105,221,376
Ensembl chr 1:96,083,441...96,090,454
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G |
Fis1 |
fission, mitochondrial 1 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of FIS1 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of FIS1 mRNA |
CTD |
PMID:32369900 |
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NCBI chr12:25,345,239...25,360,135
Ensembl chr12:19,708,558...19,723,377
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G |
Flot1 |
flotillin 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of FLOT1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr20:2,922,662...2,932,906
Ensembl chr20:2,917,137...2,927,978
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G |
Fnta |
farnesyltransferase, CAAX box, subunit alpha |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of FNTA mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of FNTA mRNA |
CTD |
PMID:30611723 |
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NCBI chr16:72,767,864...72,786,193
Ensembl chr16:66,065,132...66,083,460
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G |
Fntb |
farnesyltransferase, CAAX box, subunit beta |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of FNTB mRNA |
CTD |
PMID:30611723 |
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NCBI chr 6:101,269,657...101,352,716
Ensembl chr 6:95,470,683...95,619,586
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G |
Foxa1 |
forkhead box A1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of FOXA1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of FOXA1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 6:80,838,380...80,871,195
Ensembl chr 6:75,103,503...75,136,188
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G |
Foxo1 |
forkhead box O1 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased phosphorylation of FOXO1 protein; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NFE2L2 mRNA]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NRF1 mRNA]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARGC1A mRNA]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of TFAM mRNA] |
CTD |
PMID:26847930 |
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NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:136,312,168...136,387,790
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G |
Fth1 |
ferritin heavy chain 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of FTH1 protein; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of FTH1 protein] |
CTD |
PMID:32976958 |
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NCBI chr 1:216,052,037...216,054,325
Ensembl chr 1:206,627,103...206,725,424
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G |
G6pc1 |
glucose-6-phosphatase catalytic subunit 1 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]] |
CTD |
PMID:26847930 |
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NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,257,668...86,333,804
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G |
Gba1 |
glucosylceramidase beta 1 |
multiple interactions |
ISO |
[[Palmitic Acid co-treated with Oleic Acid] results in increased abundance of Fatty Acids, Nonesterified] which results in increased expression of GBA1 mRNA; intybin inhibits the reaction [[[Palmitic Acid co-treated with Oleic Acid] results in increased abundance of Fatty Acids, Nonesterified] which results in increased expression of GBA1 mRNA] |
CTD |
PMID:36055749 |
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NCBI chr 2:176,902,141...176,916,015
Ensembl chr 2:174,609,403...174,618,263
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G |
Gcg |
glucagon |
multiple interactions increases secretion |
ISO |
GNAT3 protein promotes the reaction [Oleic Acid results in increased secretion of GCG protein] |
CTD |
PMID:23341498 |
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NCBI chr 3:67,522,489...67,531,533
Ensembl chr 3:47,113,914...47,122,929
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GCLC protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GCLC protein] |
CTD |
PMID:36905866 |
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NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:78,630,127...78,668,544
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G |
Gclm |
glutamate cysteine ligase, modifier subunit |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GCLM protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GCLM protein] |
CTD |
PMID:36905866 |
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NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:210,347,482...210,367,535
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G |
Ggps1 |
geranylgeranyl diphosphate synthase 1 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of GGPS1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr17:55,958,750...55,982,762
Ensembl chr17:51,263,263...51,276,220
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G |
Ggt1 |
gamma-glutamyltransferase 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of GGT1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,700...13,108,442
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G |
Glp1r |
glucagon-like peptide 1 receptor |
multiple interactions affects localization |
EXP |
[Glucose co-treated with Oleic Acid] results in decreased expression of GLP1R protein; Acetylcysteine inhibits the reaction [Oleic Acid results in increased degradation of and results in decreased expression of GLP1R protein]; Chloroquine inhibits the reaction [Oleic Acid results in increased degradation of and results in decreased expression of GLP1R protein]; exenatide inhibits the reaction [[Glucose co-treated with Oleic Acid] results in decreased expression of GLP1R protein]; Oleic Acid results in increased degradation of and results in decreased expression of GLP1R protein; wortmannin inhibits the reaction [Oleic Acid results in increased degradation of and results in decreased expression of GLP1R protein] Oleic Acid affects the localization of GLP1R protein |
CTD |
PMID:22925809 |
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NCBI chr20:8,973,393...9,011,622
Ensembl chr20:8,972,004...9,010,241
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G |
Glud1 |
glutamate dehydrogenase 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of GLUD1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr16:9,646,569...9,680,215
Ensembl chr16:9,640,312...9,673,957
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G |
Gna11 |
G protein subunit alpha 11 |
increases expression |
EXP |
Oleic Acid results in increased expression of GNA11 protein |
CTD |
PMID:20804650 |
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NCBI chr 7:8,814,285...8,828,628
Ensembl chr 7:8,162,750...8,179,812
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G |
Gnaq |
G protein subunit alpha q |
increases expression |
EXP |
Oleic Acid results in increased expression of GNAQ protein |
CTD |
PMID:20804650 |
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NCBI chr 1:222,852,453...223,098,754
Ensembl chr 1:213,424,465...213,667,672
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G |
Gnat3 |
G protein subunit alpha transducin 3 |
multiple interactions |
ISO |
GNAT3 protein promotes the reaction [Oleic Acid results in increased secretion of GCG protein] |
CTD |
PMID:23341498 |
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NCBI chr 4:18,054,551...18,104,332
Ensembl chr 4:17,162,490...17,212,283
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G |
Gpam |
glycerol-3-phosphate acyltransferase, mitochondrial |
multiple interactions |
ISO |
[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of GPAM protein; acadesine inhibits the reaction [[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of GPAM protein]; GW 6471 inhibits the reaction [[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of GPAM protein] |
CTD |
PMID:33508418 |
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NCBI chr 1:264,111,599...264,176,112
Ensembl chr 1:254,106,331...254,142,639
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G |
Gpat3 |
glycerol-3-phosphate acyltransferase 3 |
increases expression multiple interactions |
ISO |
Oleic Acid results in increased expression of GPAT3 mRNA [GW 4064 co-treated with Oleic Acid] results in decreased expression of GPAT3 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of GPAT3 mRNA |
CTD |
PMID:30611723 |
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NCBI chr14:9,018,762...9,072,552
Ensembl chr14:8,714,373...8,766,490
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G |
Gpat4 |
glycerol-3-phosphate acyltransferase 4 |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of GPAT4 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of GPAT4 mRNA |
CTD |
PMID:30611723 |
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NCBI chr16:75,515,935...75,555,431
Ensembl chr16:68,819,079...68,852,901
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G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in increased activity of GPT protein; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased activity of GPT protein] |
CTD |
PMID:32976958 |
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NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:108,416,642...108,419,494
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G |
Gpx4 |
glutathione peroxidase 4 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GPX4 protein; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GPX4 protein]; NFE2L2 protein affects the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GPX4 protein] |
CTD |
PMID:32976958 |
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NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:9,650,185...9,652,982
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G |
Greb1 |
growth regulating estrogen receptor binding 1 |
increases expression multiple interactions |
ISO |
Oleic Acid results in increased expression of GREB1 mRNA Tamoxifen inhibits the reaction [Oleic Acid results in increased expression of GREB1 mRNA] |
CTD |
PMID:38191086 |
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NCBI chr 6:45,169,289...45,321,973
Ensembl chr 6:39,440,504...39,581,633
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions decreases phosphorylation |
ISO |
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [NAD inhibits the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein]]; [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride co-treated with NAD] inhibits the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein]; NAD inhibits the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein]; PARP1 protein affects the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein] |
CTD |
PMID:25536389 |
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NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646
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G |
Gsta1 |
glutathione S-transferase alpha 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of GSTA1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:23,703,477...23,720,121
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G |
Hadh |
hydroxyacyl-CoA dehydrogenase |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of HADH mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of HADH mRNA |
CTD |
PMID:30611723 |
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NCBI chr 2:222,462,049...222,504,446
Ensembl chr 2:219,787,927...219,830,353
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G |
Hadha |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha |
increases expression multiple interactions |
ISO |
Oleic Acid results in increased expression of HADHA mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of HADHA mRNA; [[Palmitic Acid co-treated with Oleic Acid] results in increased abundance of Fatty Acids, Nonesterified] which results in decreased expression of HADHA mRNA; [[Palmitic Acid co-treated with Oleic Acid] results in increased abundance of Fatty Acids, Nonesterified] which results in decreased expression of HADHA protein; [Farnesol analog co-treated with Oleic Acid] results in increased expression of HADHA mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of HADHA mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of HADHA mRNA; GW 7647 promotes the reaction [Oleic Acid results in increased expression of HADHA mRNA]; intybin inhibits the reaction [[[Palmitic Acid co-treated with Oleic Acid] results in increased abundance of Fatty Acids, Nonesterified] which results in decreased expression of HADHA mRNA]; intybin inhibits the reaction [[[Palmitic Acid co-treated with Oleic Acid] results in increased abundance of Fatty Acids, Nonesterified] which results in decreased expression of HADHA protein]; lactucin inhibits the reaction [[[Palmitic Acid co-treated with Oleic Acid] results in increased abundance of Fatty Acids, Nonesterified] which results in decreased expression of HADHA mRNA]; lactucin inhibits the reaction [[[Palmitic Acid co-treated with Oleic Acid] results in increased abundance of Fatty Acids, Nonesterified] which results in decreased expression of HADHA protein] |
CTD |
PMID:30611723 PMID:36055749 |
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NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:26,187,956...26,227,869
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G |
Hadhb |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta |
multiple interactions increases expression |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of HADHB mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of HADHB mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of HADHB mRNA; GW 7647 promotes the reaction [Oleic Acid results in increased expression of HADHB mRNA]; Oleic Acid promotes the reaction [GW 7647 results in increased expression of HADHB mRNA] |
CTD |
PMID:30611723 |
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NCBI chr 6:31,873,404...31,907,557
Ensembl chr 6:26,153,578...26,184,869
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G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
increases secretion |
ISO |
Oleic Acid results in increased secretion of HAVCR1 protein |
CTD |
PMID:31686351 |
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NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,119,088...31,151,698
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of HIF1A protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of HIF1A protein |
CTD |
PMID:30547786 |
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NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:92,624,390...92,669,261
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G |
Hilpda |
hypoxia inducible lipid droplet-associated |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of HILPDA protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of HILPDA protein |
CTD |
PMID:30547786 |
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NCBI chr 4:58,836,463...58,839,423
Ensembl chr 4:57,871,110...57,874,557
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of HMGCR mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of HMGCR mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of HMGCR mRNA [[Palmitic Acid co-treated with Oleic Acid] co-treated with IFNA2 protein alternative form] results in decreased expression of HMGCR protein |
CTD |
PMID:30611723 PMID:31299271 |
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NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:27,997,525...28,019,703
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G |
Hmgcs1 |
3-hydroxy-3-methylglutaryl-CoA synthase 1 |
multiple interactions |
ISO |
[perfluorodecanoic acid co-treated with Oleic Acid] results in increased expression of HMGCS1 mRNA |
CTD |
PMID:36423729 |
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NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:51,649,497...51,667,100
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions |
ISO |
[gastrodin co-treated with Oleic Acid] results in increased expression of HMOX1 protein; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein; dorsomorphin inhibits the reaction [[gastrodin co-treated with Oleic Acid] results in increased expression of HMOX1 protein]; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein]; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein] |
CTD |
PMID:26634892 PMID:32976958 PMID:36905866 |
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NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079
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G |
Hnf4a |
hepatocyte nuclear factor 4, alpha |
multiple interactions increases expression |
EXP ISO |
sophocarpine inhibits the reaction [Oleic Acid results in increased expression of HNF4A protein] [Palmitic Acid co-treated with Oleic Acid] affects the expression of HNF4A mRNA |
CTD |
PMID:23395669 PMID:30547786 |
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NCBI chr 3:172,606,220...172,667,758
Ensembl chr 3:152,186,787...152,248,320
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G |
Hsdl2 |
hydroxysteroid dehydrogenase like 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of HSDL2 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of HSDL2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 5:79,238,881...79,274,051
Ensembl chr 5:74,443,872...74,479,839
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
increases expression multiple interactions |
EXP ISO |
Oleic Acid results in increased expression of HSPA5 mRNA [Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein]]; Oleic Acid inhibits the reaction [[Palmitates co-treated with bisphenol A] results in increased expression of HSPA5 mRNA]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein] [Palmitic Acid co-treated with Oleic Acid] affects the expression of HSPA5 mRNA |
CTD |
PMID:24349266 PMID:30547786 PMID:32976987 PMID:37009739 |
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NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:18,055,405...18,059,891
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G |
Il18 |
interleukin 18 |
multiple interactions |
ISO |
[perfluorodecanoic acid co-treated with Oleic Acid] results in increased expression of IL18 mRNA; [perfluorodecanoic acid co-treated with Oleic Acid] results in increased secretion of IL18 protein |
CTD |
PMID:36423729 |
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NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:50,906,960...50,932,887
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G |
Il1a |
interleukin 1 alpha |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of IL1A mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of IL1A mRNA |
CTD |
PMID:30547786 |
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NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression |
EXP ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein; Dexamethasone inhibits the reaction [Oleic Acid results in increased expression of IL1B mRNA]; gossypin inhibits the reaction [Oleic Acid results in increased expression of IL1B mRNA]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein] [Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein]]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein] [Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B mRNA; [perfluorodecanoic acid co-treated with Oleic Acid] results in increased expression of IL1B mRNA; [perfluorodecanoic acid co-treated with Oleic Acid] results in increased secretion of IL1B protein; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B mRNA] |
CTD |
PMID:26190035 PMID:36423729 PMID:37009739 PMID:37696682 PMID:38103844 |
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NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415
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G |
Il6 |
interleukin 6 |
multiple interactions increases expression decreases expression |
EXP ISO |
3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]; [Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein; Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]; coomassie Brilliant Blue inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; coomassie Brilliant Blue inhibits the reaction [Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; Dexamethasone inhibits the reaction [Oleic Acid results in increased expression of IL6 mRNA]; gossypin inhibits the reaction [Oleic Acid results in increased expression of IL6 mRNA]; Resveratrol inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; Resveratrol inhibits the reaction [Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; SB 203580 inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; SB 203580 inhibits the reaction [Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]] [Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 protein; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 protein]]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 protein] Oleic Acid results in decreased expression of IL6 mRNA Oleic Acid results in increased expression of IL6 mRNA; Oleic Acid results in increased expression of IL6 protein [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of IL6 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of IL6 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of IL6 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 mRNA]; dorsomorphin inhibits the reaction [gastrodin inhibits the reaction [Oleic Acid results in increased expression of IL6 mRNA]]; gastrodin inhibits the reaction [Oleic Acid results in increased expression of IL6 mRNA]; Sorafenib inhibits the reaction [Oleic Acid results in increased expression of IL6 protein] |
CTD |
PMID:25348860 PMID:26634892 PMID:30611723 PMID:32918399 PMID:37009739 PMID:37696682 PMID:38103844 More...
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NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
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G |
Ins1 |
insulin 1 |
multiple interactions increases secretion |
ISO EXP |
[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]; [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]] Oleic Acid results in increased secretion of INS1 protein Oleic Acid promotes the reaction [Glucose results in increased secretion of INS1 protein] |
CTD |
PMID:24349266 PMID:26847930 |
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NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:251,244,973...251,245,536
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G |
Ins2 |
insulin 2 |
multiple interactions |
ISO |
[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 mRNA; [Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 protein; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 mRNA]; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 protein]; troglitazone promotes the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 mRNA]; troglitazone promotes the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 protein] [[Dexamethasone co-treated with INS protein co-treated with 1-Methyl-3-isobutylxanthine] co-treated with alitretinoin] results in increased uptake of Oleic Acid |
CTD |
PMID:10777552 PMID:11292061 |
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NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:197,843,281...197,864,775
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G |
Insr |
insulin receptor |
decreases phosphorylation multiple interactions |
ISO |
Oleic Acid results in decreased phosphorylation of INSR protein 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased phosphorylation of INSR protein]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [NAD inhibits the reaction [Oleic Acid results in decreased phosphorylation of INSR protein]]; [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride co-treated with NAD] inhibits the reaction [Oleic Acid results in decreased phosphorylation of INSR protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased phosphorylation of INSR protein]; NAD inhibits the reaction [Oleic Acid results in decreased phosphorylation of INSR protein]; PARP1 protein affects the reaction [Oleic Acid results in decreased phosphorylation of INSR protein] |
CTD |
PMID:25536389 |
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NCBI chr12:5,991,135...6,129,275
Ensembl chr12:1,197,100...1,330,883
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G |
Irs2 |
insulin receptor substrate 2 |
multiple interactions decreases expression |
EXP ISO |
IRS2 inhibits the reaction [Oleic Acid results in increased cleavage of CASP9 protein]; Oleic Acid inhibits the reaction [IRS2 results in increased phosphorylation of and results in increased activity of AKT1 protein] Oleic Acid results in decreased expression of IRS2 protein Metformin inhibits the reaction [Oleic Acid results in decreased expression of IRS2 protein]; qidan inhibits the reaction [Oleic Acid results in decreased expression of IRS2 protein] |
CTD |
PMID:14604813 PMID:36592823 |
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NCBI chr16:85,190,310...85,214,543
Ensembl chr16:78,485,045...78,512,482
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G |
Iyd |
iodotyrosine deiodinase |
multiple interactions |
ISO |
Oleic Acid inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] |
CTD |
PMID:33352258 |
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NCBI chr 1:42,410,099...42,425,414
Ensembl chr 1:40,004,041...40,019,319
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G |
Jak1 |
Janus kinase 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of JAK1 protein; [Palmitic Acid co-treated with Oleic Acid] affects the expression of JAK1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of JAK1 protein |
CTD |
PMID:30547786 |
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NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:115,780,248...115,888,926
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G |
Jak2 |
Janus kinase 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of JAK2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:226,995,334...227,054,189
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G |
Keap1 |
Kelch-like ECH-associated protein 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in increased expression of KEAP1 protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of KEAP1 protein] |
CTD |
PMID:36905866 |
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NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:19,768,375...19,777,862
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G |
Lamb1 |
laminin subunit beta 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of LAMB1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of LAMB1 mRNA |
CTD |
PMID:30547786 |
|
NCBI chr 6:53,562,849...53,630,118
Ensembl chr 6:47,835,525...47,902,585
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G |
Ldlr |
low density lipoprotein receptor |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of LDLR mRNA |
CTD |
PMID:30547786 |
|
NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:20,270,041...20,294,580
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G |
Lep |
leptin |
decreases expression increases expression multiple interactions |
ISO EXP |
Oleic Acid results in decreased expression of LEP mRNA Oleic Acid results in increased expression of LEP mRNA sophocarpine inhibits the reaction [Oleic Acid results in increased expression of LEP mRNA] |
CTD |
PMID:9002984 PMID:23395669 |
|
NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:57,661,131...57,675,262
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G |
Lipc |
lipase C, hepatic type |
multiple interactions decreases expression |
ISO |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of Oleic Acid Oleic Acid results in decreased expression of LIPC mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of LIPC mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of LIPC mRNA; Sorafenib inhibits the reaction [Oleic Acid results in decreased expression of LIPC mRNA] |
CTD |
PMID:24777581 PMID:30611723 PMID:32918399 |
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NCBI chr 8:80,390,470...80,516,463
Ensembl chr 8:71,509,635...71,635,464
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G |
Lipg |
lipase G, endothelial type |
multiple interactions |
ISO |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of Oleic Acid |
CTD |
PMID:24777581 |
|
NCBI chr18:70,790,077...70,811,259
Ensembl chr18:68,514,923...68,536,260
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G |
Lox |
lysyl oxidase |
increases activity |
ISO |
Oleic Acid results in increased activity of LOX protein |
CTD |
PMID:26240151 |
|
NCBI chr18:48,162,889...48,175,640
Ensembl chr18:45,967,343...46,041,477
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G |
Lpin1 |
lipin 1 |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of LPIN1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of LPIN1 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 6:45,039,110...45,145,845
Ensembl chr 6:39,312,748...39,417,097
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G |
Lpin2 |
lipin 2 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of LPIN2 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of LPIN2 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 9:118,529,988...118,604,796
Ensembl chr 9:111,083,745...111,158,193
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G |
Lpin3 |
lipin 3 |
decreases expression multiple interactions |
ISO |
Oleic Acid results in decreased expression of LPIN3 mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of LPIN3 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of LPIN3 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 3:169,953,479...169,978,034
Ensembl chr 3:149,534,051...149,558,327
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of MAP1LC3B mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased lipidation of MAP1LC3B protein |
CTD |
PMID:30547786 PMID:36905866 |
|
NCBI chr19:66,571,631...66,582,270
Ensembl chr19:49,665,791...49,677,690 Ensembl chr16:49,665,791...49,677,690
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G |
Map3k8 |
mitogen-activated protein kinase kinase kinase 8 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MAP3K8 mRNA |
CTD |
PMID:30547786 |
|
NCBI chr17:58,078,175...58,098,455
Ensembl chr17:53,383,131...53,403,216
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G |
Map4k4 |
mitogen-activated protein kinase kinase kinase kinase 4 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MAP4K4 mRNA |
CTD |
PMID:30547786 |
|
NCBI chr 9:49,696,573...49,822,353
Ensembl chr 9:42,200,278...42,326,698
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO |
Oleic Acid inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:38456238 |
|
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk14 |
mitogen activated protein kinase 14 |
multiple interactions |
ISO |
Oleic Acid inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK14 protein] |
CTD |
PMID:38456238 |
|
NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,749,670...6,810,589
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO |
Oleic Acid inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:38456238 |
|
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions |
ISO |
Oleic Acid inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK8 protein] |
CTD |
PMID:38456238 |
|
NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981
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G |
Mcat |
malonyl-CoA-acyl carrier protein transacylase |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of MCAT mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of MCAT mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 7:116,573,632...116,585,767
Ensembl chr 7:114,693,612...114,704,542
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G |
Mecr |
mitochondrial trans-2-enoyl-CoA reductase |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of MECR mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 5:149,313,765...149,339,964
Ensembl chr 5:144,029,731...144,055,863
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G |
Mff |
mitochondrial fission factor |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of MFF mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of MFF mRNA |
CTD |
PMID:32369900 |
|
NCBI chr 9:91,455,931...91,484,171
Ensembl chr 9:84,007,798...84,036,039
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G |
Mfn1 |
mitofusin 1 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of MFN1 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of MFN1 mRNA |
CTD |
PMID:32369900 |
|
NCBI chr 2:117,240,525...117,288,017
Ensembl chr 2:115,313,401...115,359,640
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G |
Mgll |
monoglyceride lipase |
multiple interactions |
EXP |
[Oleic Acid co-treated with Palmitic Acid] affects the reaction [Chlorpyrifos results in decreased activity of MGLL protein] |
CTD |
PMID:35151815 |
|
NCBI chr 4:122,749,436...122,851,440
Ensembl chr 4:121,192,195...121,294,179
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G |
Mir30a |
microRNA 30a |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MIR30A mRNA |
CTD |
PMID:39423997 |
|
NCBI chr 9:33,233,941...33,234,011
Ensembl chr 9:25,737,600...25,737,670
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G |
Mir497 |
microRNA 497 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MIR497 mRNA; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of BACE1 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein]]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MIR497 mRNA] |
CTD |
PMID:37009739 |
|
NCBI chr10:55,450,171...55,450,239
Ensembl chr10:54,951,505...54,951,584
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G |
Mir675 |
microRNA 675 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MIR675 mRNA |
CTD |
PMID:39423997 |
|
NCBI chr 1:207,161,752...207,161,835
Ensembl chr 1:197,732,275...197,732,358
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G |
Mlkl |
mixed lineage kinase domain like pseudokinase |
multiple interactions increases phosphorylation |
ISO |
necrostatin-1 inhibits the reaction [Oleic Acid results in increased phosphorylation of MLKL protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased phosphorylation of MLKL protein] |
CTD |
PMID:36273635 |
|
NCBI chr19:56,186,860...56,213,886
Ensembl chr19:39,276,785...39,304,502
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G |
Mlxipl |
MLX interacting protein-like |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of MLXIPL mRNA; [Farnesol analog co-treated with Oleic Acid] results in decreased expression of MLXIPL mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of MLXIPL mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of MLXIPL mRNA |
CTD |
PMID:30611723 |
|
NCBI chr12:27,178,158...27,213,675
Ensembl chr12:21,543,576...21,577,112
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G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MMP2 mRNA |
CTD |
PMID:26187275 |
|
NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of MMP9 protein; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of MMP9 protein] |
CTD |
PMID:38103844 |
|
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120
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G |
Mt1 |
metallothionein 1 |
multiple interactions |
EXP |
[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of MT1 mRNA]; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of MT1 mRNA; Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of MT1 mRNA] |
CTD |
PMID:26854922 |
|
NCBI chr19:10,831,959...10,832,975
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049 Ensembl chr X:10,826,032...10,827,049
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G |
Mt2 |
metallothionein 2 |
multiple interactions |
EXP |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of MT2A mRNA |
CTD |
PMID:26854922 |
|
NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,832,002...10,832,784
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G |
Mttp |
microsomal triglyceride transfer protein |
multiple interactions decreases expression |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of MTTP mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of MTTP mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MTTP mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MTTP mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of MTTP mRNA; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MTTP mRNA]; Sorafenib inhibits the reaction [Oleic Acid results in decreased expression of MTTP mRNA] |
CTD |
PMID:30547786 PMID:30611723 PMID:32918399 PMID:36347319 PMID:38092172 |
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NCBI chr 2:229,286,501...229,327,650
Ensembl chr 2:226,613,090...226,654,239
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions increases expression |
ISO |
[gastrodin co-treated with Oleic Acid] results in increased phosphorylation of and affects the localization of NFE2L2 protein; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of and affects the localization of NFE2L2 protein; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of NFE2L2 protein; dorsomorphin inhibits the reaction [[gastrodin co-treated with Oleic Acid] results in increased phosphorylation of and affects the localization of NFE2L2 protein]; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of NFE2L2 protein]; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of and affects the localization of NFE2L2 protein]; NFE2L2 protein affects the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GPX4 protein]; NFE2L2 protein affects the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein] [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NFE2L2 mRNA; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NFE2L2 mRNA] Oleic Acid results in increased expression of NFE2L2 mRNA; Oleic Acid results in increased expression of NFE2L2 protein |
CTD |
PMID:26634892 PMID:26847930 PMID:28555106 PMID:32976958 PMID:36905866 |
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NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737
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G |
Nos3 |
nitric oxide synthase 3 |
decreases expression |
ISO |
Oleic Acid results in decreased expression of NOS3 mRNA |
CTD |
PMID:16895544 |
|
NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:10,793,834...10,814,166
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of NQO1 protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of NQO1 protein] |
CTD |
PMID:36905866 |
|
NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557
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G |
Nr0b2 |
nuclear receptor subfamily 0, group B, member 2 |
decreases expression increases expression multiple interactions |
ISO EXP |
Oleic Acid results in decreased expression of NR0B2 mRNA Oleic Acid results in increased expression of NR0B2 mRNA [Farnesol analog co-treated with Oleic Acid] results in decreased expression of NR0B2 mRNA; [GW 4064 co-treated with Oleic Acid] results in increased expression of NR0B2 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of NR0B2 mRNA |
CTD |
PMID:30611723 PMID:32738331 |
|
NCBI chr 5:151,063,160...151,066,475
Ensembl chr 5:145,779,294...145,782,609
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G |
Nr1h3 |
nuclear receptor subfamily 1, group H, member 3 |
multiple interactions |
ISO EXP |
[Oleic Acid co-treated with Fenofibrate] affects the expression of NR1H3 mRNA; [Oleic Acid co-treated with muraglitazar] results in increased expression of NR1H3 mRNA; [Oleic Acid co-treated with Rosiglitazone] results in increased expression of NR1H3 mRNA; [Oleic Acid co-treated with tesaglitazar] affects the expression of NR1H3 mRNA; [Oleic Acid co-treated with Troglitazone] affects the expression of NR1H3 mRNA [Oleic Acid co-treated with Palmitic Acid] results in increased expression of NR1H3 mRNA |
CTD |
PMID:24534255 PMID:26190035 |
|
NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:77,158,808...77,168,722
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
multiple interactions decreases expression |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of NR1H4 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of NR1H4 mRNA; [Oleic Acid co-treated with Bezafibrate] results in increased expression of NR1H4 mRNA; [Oleic Acid co-treated with Fenofibrate] results in decreased expression of NR1H4 mRNA; [Oleic Acid co-treated with muraglitazar] results in increased expression of NR1H4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of NR1H4 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of NR1H4 mRNA Oleic Acid results in decreased expression of NR1H4 mRNA |
CTD |
PMID:24534255 PMID:30547786 PMID:30611723 |
|
NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:23,846,122...23,942,047
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G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of NR1I3 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of NR1I3 mRNA; [Oleic Acid co-treated with Fenofibrate] results in increased expression of NR1I3 mRNA; [Oleic Acid co-treated with muraglitazar] results in increased expression of NR1I3 mRNA; [Oleic Acid co-treated with Rosiglitazone] results in decreased expression of NR1I3 mRNA; [Oleic Acid co-treated with Troglitazone] affects the expression of NR1I3 mRNA |
CTD |
PMID:24534255 PMID:30611723 |
|
NCBI chr13:86,165,327...86,170,362
Ensembl chr13:83,632,899...83,637,906
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G |
Nrf1 |
nuclear respiratory factor 1 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NRF1 mRNA; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NRF1 mRNA] |
CTD |
PMID:26847930 |
|
NCBI chr 4:59,632,366...59,738,166
Ensembl chr 4:58,664,957...58,825,328
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G |
P2rx7 |
purinergic receptor P2X 7 |
multiple interactions |
EXP |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 protein; Resveratrol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 mRNA]; Resveratrol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 protein] |
CTD |
PMID:25348860 |
|
NCBI chr12:39,550,531...39,594,984
Ensembl chr12:33,879,745...33,934,619
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
increases cleavage increases activity multiple interactions |
ISO |
Oleic Acid results in increased cleavage of PARP1 protein Oleic Acid results in increased activity of PARP1 protein [NAD co-treated with Oleic Acid] results in increased activity of PARP1 protein; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[NAD co-treated with Oleic Acid] results in increased activity of PARP1 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in increased activity of PARP1 protein]; PARP1 protein affects the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein]; PARP1 protein affects the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein]; PARP1 protein affects the reaction [Oleic Acid results in decreased phosphorylation of INSR protein] |
CTD |
PMID:21132278 PMID:25536389 PMID:30165350 |
|
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404
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G |
Pc |
pyruvate carboxylase |
decreases expression |
EXP |
Oleic Acid results in decreased expression of PC mRNA |
CTD |
PMID:24349266 |
|
NCBI chr 1:211,228,708...211,327,792
Ensembl chr 1:201,804,267...201,898,380
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G |
Pck1 |
phosphoenolpyruvate carboxykinase 1 |
multiple interactions increases expression |
ISO |
[Glucose deficiency co-treated with Clofibrate co-treated with Oleic Acid] results in increased expression of PCK1 mRNA; [Glucose deficiency co-treated with Oleic Acid] results in increased expression of PCK1 mRNA; [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]; Dexamethasone inhibits the reaction [Oleic Acid results in increased expression of PCK1 mRNA]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]] [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of PCK1 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of PCK1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of PCK1 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of PCK1 mRNA |
CTD |
PMID:8536680 PMID:9518257 PMID:26847930 PMID:30611723 |
|
NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:161,930,256...161,936,191
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G |
Pdgfb |
platelet derived growth factor subunit B |
multiple interactions increases expression |
ISO |
Sorafenib inhibits the reaction [Oleic Acid results in increased expression of PDGFB mRNA] |
CTD |
PMID:32918399 |
|
NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:111,540,345...111,557,984
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G |
Pdk4 |
pyruvate dehydrogenase kinase 4 |
increases expression multiple interactions |
ISO |
Oleic Acid results in increased expression of PDK4 mRNA [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PDK4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PDK4 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PDK4 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PDK4 protein |
CTD |
PMID:26739624 PMID:30547786 |
|
NCBI chr 4:34,558,327...34,568,329
Ensembl chr 4:33,589,799...33,601,850
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G |
Pdss1 |
decaprenyl diphosphate synthase subunit 1 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of PDSS1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of PDSS1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr17:89,964,768...90,006,819
Ensembl chr17:85,060,106...85,098,730
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G |
Pebp1 |
phosphatidylethanolamine binding protein 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PEBP1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of PEBP1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr12:44,946,307...44,967,890
Ensembl chr12:39,302,840...39,307,862
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G |
Pecr |
peroxisomal trans-2-enoyl-CoA reductase |
decreases expression multiple interactions |
ISO |
Oleic Acid results in decreased expression of PECR mRNA [GW 4064 co-treated with Oleic Acid] results in decreased expression of PECR mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of PECR mRNA |
CTD |
PMID:30611723 |
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NCBI chr 9:81,347,170...81,375,809
Ensembl chr 9:73,897,880...73,926,511
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G |
Pgam5 |
PGAM family member 5, mitochondrial serine/threonine protein phosphatase |
multiple interactions |
ISO |
PGAM5 protein promotes the reaction [Oleic Acid results in increased expression of SQSTM1 protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased phosphorylation of MLKL protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased phosphorylation of RIPK1 protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased phosphorylation of RIPK3 protein] |
CTD |
PMID:36273635 |
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NCBI chr12:52,069,023...52,076,131
Ensembl chr12:46,409,369...46,416,420
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G |
Pik3c2a |
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of PIK3C2A mRNA |
CTD |
PMID:30547786 |
|
NCBI chr 1:180,012,248...180,117,786
Ensembl chr 1:170,577,942...170,683,472
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G |
Pink1 |
PTEN induced kinase 1 |
multiple interactions decreases expression |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of PINK1 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of PINK1 mRNA; Metformin inhibits the reaction [Oleic Acid results in decreased expression of PINK1 protein]; qidan inhibits the reaction [Oleic Acid results in decreased expression of PINK1 protein] |
CTD |
PMID:32369900 PMID:36592823 |
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NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:150,530,523...150,542,635
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G |
Pklr |
pyruvate kinase L/R |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PKLR mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of PKLR mRNA |
CTD |
PMID:30547786 |
|
NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:174,543,039...174,551,870
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G |
Pld1 |
phospholipase D1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PLD1 mRNA |
CTD |
PMID:30547786 |
|
NCBI chr 2:112,777,820...112,975,857
Ensembl chr 2:110,893,608...111,047,692
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G |
Plek |
pleckstrin |
multiple interactions |
ISO |
Oleic Acid promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) results in increased phosphorylation of PLEK protein] |
CTD |
PMID:8928743 |
|
NCBI chr14:95,598,650...95,631,326
Ensembl chr14:91,397,019...91,454,131
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G |
Plin1 |
perilipin 1 |
increases expression |
ISO |
Oleic Acid results in increased expression of PLIN1 mRNA |
CTD |
PMID:26739624 |
|
NCBI chr 1:143,073,612...143,086,199
Ensembl chr 1:133,664,892...133,676,828
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G |
Plin2 |
perilipin 2 |
multiple interactions increases expression |
EXP ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PLIN2 mRNA; Oleic Acid promotes the reaction [LG 100268 results in increased expression of PLIN2 protein]; Oleic Acid promotes the reaction [pirinixic acid results in increased expression of PLIN2 protein] Rimonabant inhibits the reaction [Oleic Acid results in increased expression of PLIN2 protein] Oleic Acid results in increased expression of PLIN2 mRNA; Oleic Acid results in increased expression of PLIN2 protein [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of PLIN2 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of PLIN2 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of PLIN2 mRNA; [Oleic Acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of PLIN2 mRNA; [Oleic Acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of PLIN2 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PLIN2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PLIN2 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PLIN2 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PLIN2 protein; Bezafibrate promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA]; Dichlorodiphenyl Dichloroethylene promotes the reaction [Oleic Acid results in increased expression of PLIN2 protein]; Diethylhexyl Phthalate promotes the reaction [Oleic Acid results in increased expression of PLIN2 protein]; Fenofibrate promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA]; muraglitazar promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA]; Rosiglitazone promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA]; tesaglitazar promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA]; Troglitazone promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA] |
CTD |
PMID:16489205 PMID:24534255 PMID:25048947 PMID:26739624 PMID:30547786 PMID:30611723 PMID:31570772 PMID:38092172 More...
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NCBI chr 5:106,202,634...106,258,748
Ensembl chr 5:101,154,411...101,242,319
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G |
Plin3 |
perilipin 3 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in increased expression of PLIN3 mRNA |
CTD |
PMID:30547786 |
|
NCBI chr 9:1,198,336...1,210,212
Ensembl chr 9:1,102,366...1,123,147
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G |
Plin4 |
perilipin 4 |
multiple interactions increases expression |
ISO |
Bezafibrate promotes the reaction [Oleic Acid results in increased expression of PLIN4 mRNA]; muraglitazar promotes the reaction [Oleic Acid results in increased expression of PLIN4 mRNA]; rosiglitazone promotes the reaction [Oleic Acid results in increased expression of PLIN4 mRNA]; tesaglitazar promotes the reaction [Oleic Acid results in increased expression of PLIN4 mRNA]; troglitazone promotes the reaction [Oleic Acid results in increased expression of PLIN4 mRNA] |
CTD |
PMID:24534255 |
|
NCBI chr 9:1,016,334...1,025,249
Ensembl chr 9:929,176...938,056
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G |
Plin5 |
perilipin 5 |
multiple interactions |
EXP |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PLIN5 mRNA; tetrabromobisphenol A promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PLIN5 mRNA] |
CTD |
PMID:25048947 |
|
NCBI chr 9:1,026,910...1,033,352
Ensembl chr 9:939,747...946,120
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G |
Plpp6 |
phospholipid phosphatase 6 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of PLPP6 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of PLPP6 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 1:236,092,642...236,095,494
Ensembl chr 1:226,679,100...226,681,949
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G |
Pnpla3 |
patatin-like phospholipase domain containing 3 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PNPLA3 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of PNPLA3 mRNA |
CTD |
PMID:30547786 |
|
NCBI chr 7:117,173,485...117,194,065
Ensembl chr 7:115,293,538...115,314,077
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G |
Pon1 |
paraoxonase 1 |
multiple interactions decreases activity |
ISO |
[Calcium co-treated with Oleic Acid] results in increased stability of PON1 protein; Calcium promotes the reaction [Oleic Acid inhibits the reaction [4-hydroxymercuribenzoate results in decreased activity of PON1 protein]]; Oleic Acid inhibits the reaction [4-hydroxymercuribenzoate results in decreased activity of PON1 protein]; Oleic Acid inhibits the reaction [[Ascorbic Acid co-treated with Copper Sulfate] results in decreased activity of PON1 protein]; Oleic Acid inhibits the reaction [Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]]; Oleic Acid inhibits the reaction [Hydrogen Peroxide results in decreased activity of PON1 protein]; Oleic Acid inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon] Oleic Acid results in decreased activity of PON1 protein |
CTD |
PMID:12871208 PMID:15104111 PMID:15375178 |
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NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:33,294,722...33,321,360
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions affects binding increases expression affects abundance decreases expression increases activity |
ISO EXP |
Diethylhexyl Phthalate inhibits the reaction [PPARA protein affects the abundance of Oleic Acid]; Oleic Acid binds to and results in increased activity of PPARA protein; Oleic Acid inhibits the reaction [troglitazone results in decreased expression of PPARA mRNA]; PPARA protein promotes the reaction [Oleic Acid results in decreased expression of SLC13A1 mRNA]; PPARA protein promotes the reaction [Oleic Acid results in decreased expression of SLC16A9 mRNA]; PPARA protein promotes the reaction [Oleic Acid results in increased expression of ABCD3 mRNA]; PPARA protein promotes the reaction [Oleic Acid results in increased expression of CYP2C65 mRNA]; PPARA protein promotes the reaction [Oleic Acid results in increased expression of CYP4F16 mRNA]; PPARA protein promotes the reaction [Oleic Acid results in increased expression of SLC27A4 mRNA]; PPARA protein promotes the reaction [Oleic Acid results in increased expression of SLC6A3 mRNA] Oleic Acid binds to PPARA protein Oleic Acid results in increased expression of PPARA mRNA; Oleic Acid results in increased expression of PPARA protein [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARA mRNA; [tetrabromobisphenol A co-treated with Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA; [Triiodothyronine co-treated with Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA]; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein]; Oleic Acid binds to and results in increased activity of PPARA protein; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein] Oleic Acid results in decreased expression of PPAR mRNA; Oleic Acid results in decreased expression of PPARA mRNA; Oleic Acid results in decreased expression of PPARA protein [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of PPARA mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of PPARA mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of PPARA mRNA; [Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of PPARA protein; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PPARA mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of PPARA mRNA; [Vehicle Emissions results in increased abundance of Particulate Matter] inhibits the reaction [Oleic Acid results in increased expression of PPARA mRNA]; Benzo(a)pyrene inhibits the reaction [Estradiol inhibits the reaction [Oleic Acid results in decreased expression of PPARA mRNA]]; Benzo(a)pyrene inhibits the reaction [Estradiol inhibits the reaction [Oleic Acid results in decreased expression of PPARA protein]]; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA]; Diethylhexyl Phthalate promotes the reaction [Oleic Acid results in increased activity of and results in increased localization of PPARA protein]; Diethylhexyl Phthalate promotes the reaction [Oleic Acid results in increased expression of PPARA protein]; Estradiol inhibits the reaction [Oleic Acid results in decreased expression of PPARA mRNA]; Estradiol inhibits the reaction [Oleic Acid results in decreased expression of PPARA protein]; GW 6471 inhibits the reaction [[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of PPARA protein]; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA]; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein]; Oleic Acid binds to and results in increased activity of PPARA protein; Oleic Acid results in increased activity of and results in increased localization of PPARA protein; Plant Extracts inhibits the reaction [Oleic Acid results in decreased expression of PPARA mRNA]; Plant Extracts inhibits the reaction [Oleic Acid results in decreased expression of PPARA protein] Oleic Acid results in increased activity of PPARA protein |
CTD |
PMID:9688458 PMID:10403814 PMID:11056218 PMID:15491415 PMID:15949695 PMID:16731579 PMID:18154422 PMID:18489776 PMID:23603006 PMID:23619606 PMID:25048947 PMID:26190035 PMID:26854922 PMID:27996362 PMID:30547786 PMID:30611723 PMID:31340670 PMID:31730885 PMID:33508418 PMID:35752307 PMID:36347319 PMID:38103844 More...
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NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346
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G |
Ppard |
peroxisome proliferator-activated receptor delta |
increases expression multiple interactions decreases expression |
ISO EXP |
Oleic Acid results in increased expression of PPARD mRNA Oleic Acid binds to and results in increased activity of PPARB protein [Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in increased expression of PPARD mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARB mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARD mRNA; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARB mRNA]; Oleic Acid binds to and results in increased activity of PPARB protein; tetrabromobisphenol A inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARD mRNA] Oleic Acid results in decreased expression of PPARD mRNA [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PPARD mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PPARD mRNA; Oleic Acid binds to and results in increased activity of PPARB protein |
CTD |
PMID:11172467 PMID:16731579 PMID:24349266 PMID:25048947 PMID:26190035 PMID:26854922 PMID:30547786 More...
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NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,298,785...6,363,968
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
increases expression affects binding multiple interactions |
ISO EXP |
Oleic Acid results in increased expression of PPARG mRNA Oleic Acid binds to PPARG protein [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of PPARG mRNA]; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA; Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA]; tetrabromobisphenol A inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA]; Triiodothyronine inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA] [cyhalothrin co-treated with Oleic Acid] results in increased expression of PPARG protein; [Farnesol analog co-treated with Oleic Acid] results in increased expression of PPARG mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of PPARG mRNA; [Oleic Acid co-treated with Fenofibrate] results in increased expression of PPARG mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG protein; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of PPARG protein; [Tamoxifen co-treated with Oleic Acid] results in increased expression of PPARG mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA]; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG protein]; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of PPARG protein]; Metformin inhibits the reaction [[cyhalothrin co-treated with Oleic Acid] results in increased expression of PPARG protein]; Oleic Acid binds to and results in increased activity of PPARG protein Oleic Acid results in increased expression of PPARG mRNA; Oleic Acid results in increased expression of PPARG protein |
CTD |
PMID:11172467 PMID:18154422 PMID:24534255 PMID:24998974 PMID:25048947 PMID:26190035 PMID:26854922 PMID:27131391 PMID:30611723 PMID:35752307 PMID:36529352 PMID:36905866 PMID:38103844 PMID:38191086 More...
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NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARGC1A mRNA; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARGC1A mRNA] |
CTD |
PMID:26847930 |
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NCBI chr14:63,073,505...63,729,215
Ensembl chr14:58,861,144...59,512,656
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G |
Prkaa1 |
protein kinase AMP-activated catalytic subunit alpha 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PRKAA1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:54,240,137...54,275,978
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G |
Prkaa2 |
protein kinase AMP-activated catalytic subunit alpha 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of PRKAA2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 5:125,036,945...125,109,010
Ensembl chr 5:119,813,226...119,879,543
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G |
Prkn |
parkin RBR E3 ubiquitin protein ligase |
decreases expression multiple interactions |
ISO |
Oleic Acid results in decreased expression of PRKN protein Metformin inhibits the reaction [Oleic Acid results in decreased expression of PRKN protein]; qidan inhibits the reaction [Oleic Acid results in decreased expression of PRKN protein] |
CTD |
PMID:36592823 |
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NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555
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G |
Psen1 |
presenilin 1 |
multiple interactions |
ISO |
[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Oleic Acid; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Oleic Acid] |
CTD |
PMID:39172838 |
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NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:103,323,120...103,371,650
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions increases expression |
ISO |
dorsomorphin inhibits the reaction [gastrodin inhibits the reaction [Oleic Acid results in increased expression of PTGS2 mRNA]]; gastrodin inhibits the reaction [Oleic Acid results in increased expression of PTGS2 mRNA] |
CTD |
PMID:26634892 |
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NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188
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G |
Rab18 |
RAB18, member RAS oncogene family |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RAB18 mRNA |
CTD |
PMID:30547786 |
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NCBI chr17:59,639,264...59,670,653
Ensembl chr17:54,943,955...54,976,043
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G |
Rabggta |
Rab geranylgeranyltransferase subunit alpha |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in decreased expression of RABGGTA mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of RABGGTA mRNA |
CTD |
PMID:30611723 |
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NCBI chr15:33,176,268...33,183,320
Ensembl chr15:29,206,157...29,213,348
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G |
Rabggtb |
Rab geranylgeranyltransferase subunit beta |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of RABGGTB mRNA; [Farnesol analog co-treated with Oleic Acid] results in decreased expression of RABGGTB mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of RABGGTB mRNA |
CTD |
PMID:30611723 |
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NCBI chr 2:245,504,586...245,510,878
Ensembl chr 2:242,844,762...242,851,050
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G |
Rb1 |
RB transcriptional corepressor 1 |
decreases phosphorylation |
ISO |
Oleic Acid results in decreased phosphorylation of RB1 protein |
CTD |
PMID:16027227 |
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NCBI chr15:54,780,858...54,911,989
Ensembl chr15:48,371,296...48,502,302
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
Oleic Acid inhibits the reaction [Particulate Matter results in increased phosphorylation of RELA protein] |
CTD |
PMID:38456238 |
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NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484
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G |
Rheb |
Ras homolog, mTORC1 binding |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RHEB mRNA |
CTD |
PMID:30547786 |
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NCBI chr 4:11,012,173...11,053,860
Ensembl chr 4:10,279,370...10,320,160
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G |
Rhob |
ras homolog family member B |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RHOB mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of RHOB mRNA |
CTD |
PMID:30547786 |
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NCBI chr 6:37,083,030...37,085,204
Ensembl chr 6:31,363,548...31,366,108
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G |
Ripk1 |
receptor interacting serine/threonine kinase 1 |
multiple interactions increases phosphorylation |
ISO |
necrostatin-1 inhibits the reaction [Oleic Acid results in increased phosphorylation of RIPK1 protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased phosphorylation of RIPK1 protein] |
CTD |
PMID:36273635 |
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NCBI chr17:31,044,983...31,077,167
Ensembl chr17:30,839,650...30,871,824
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G |
Ripk3 |
receptor-interacting serine-threonine kinase 3 |
increases phosphorylation multiple interactions |
ISO |
Oleic Acid results in increased phosphorylation of RIPK3 protein necrostatin-1 inhibits the reaction [Oleic Acid results in increased phosphorylation of RIPK3 protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased phosphorylation of RIPK3 protein] |
CTD |
PMID:36273635 |
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NCBI chr15:33,253,071...33,262,025
Ensembl chr15:29,283,145...29,292,121
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G |
Rock2 |
Rho-associated coiled-coil containing protein kinase 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ROCK2 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ROCK2 protein |
CTD |
PMID:30547786 |
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NCBI chr 6:45,407,823...45,502,773
Ensembl chr 6:39,679,082...39,774,031
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G |
Rxra |
retinoid X receptor alpha |
multiple interactions |
ISO |
Oleic Acid binds to and results in increased activity of RXRA protein |
CTD |
PMID:16731579 PMID:27131391 |
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NCBI chr 3:31,387,892...31,474,415
Ensembl chr 3:10,989,832...11,073,712
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G |
Scd |
stearoyl-CoA desaturase |
multiple interactions decreases expression |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of SCD mRNA; [Farnesol analog co-treated with Oleic Acid] results in decreased expression of SCD mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of SCD mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of SCD mRNA; [Oleic Acid co-treated with Bezafibrate] results in increased expression of SCD1 mRNA; [Oleic Acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SCD mRNA; [Oleic Acid co-treated with Fenofibrate] results in increased expression of SCD1 mRNA; [Oleic Acid co-treated with muraglitazar] results in increased expression of SCD1 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of SCD1 mRNA; [Oleic Acid co-treated with tesaglitazar] results in increased expression of SCD1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SCD mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SCD mRNA; [perfluorodecanoic acid co-treated with Oleic Acid] results in increased expression of SCD mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SCD1 mRNA] Oleic Acid results in decreased expression of SCD mRNA [Starch co-treated with Oleic Acid] results in increased expression of SCD1 mRNA; [Sucrose co-treated with Oleic Acid] results in increased expression of SCD1 mRNA |
CTD |
PMID:24534255 PMID:26895660 PMID:30547786 PMID:30611723 PMID:36423729 PMID:38092172 PMID:38103844 More...
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NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:243,269,747...243,282,562
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G |
Scp2 |
sterol carrier protein 2 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of SCP2 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 5:128,035,714...128,110,015
Ensembl chr 5:122,776,549...122,881,287
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G |
Serpine1 |
serpin family E member 1 |
multiple interactions |
ISO |
[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 mRNA; [Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SERPINE1 mRNA; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 mRNA]; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 protein]; Troglitazone promotes the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 mRNA]; Troglitazone promotes the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 protein] |
CTD |
PMID:11292061 PMID:30547786 |
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NCBI chr12:25,237,977...25,248,356
Ensembl chr12:19,601,272...19,611,657
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G |
Sirt1 |
sirtuin 1 |
increases expression multiple interactions decreases activity |
EXP ISO |
Oleic Acid results in increased expression of SIRT1 protein 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [NAD promotes the reaction [Oleic Acid results in decreased activity of SIRT1 protein]]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased activity of SIRT1 protein]; NAD promotes the reaction [Oleic Acid results in decreased activity of SIRT1 protein] [Ethanol co-treated with Oleic Acid co-treated with Palmitic Acid] results in decreased expression of SIRT1 protein |
CTD |
PMID:24349266 PMID:25536389 PMID:26854922 |
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NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260
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G |
Sirt4 |
sirtuin 4 |
decreases expression |
EXP |
Oleic Acid results in decreased expression of SIRT4 mRNA |
CTD |
PMID:24349266 |
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NCBI chr12:46,785,852...46,800,179
Ensembl chr12:41,131,262...41,139,439
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G |
Slc13a1 |
solute carrier family 13 member 1 |
multiple interactions |
ISO |
PPARA protein promotes the reaction [Oleic Acid results in decreased expression of SLC13A1 mRNA] |
CTD |
PMID:18489776 |
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NCBI chr 4:53,534,763...53,612,704
Ensembl chr 4:52,569,375...52,647,099
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G |
Slc16a9 |
solute carrier family 16, member 9 |
multiple interactions |
ISO |
PPARA protein promotes the reaction [Oleic Acid results in decreased expression of SLC16A9 mRNA] |
CTD |
PMID:18489776 |
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NCBI chr20:18,334,946...18,376,195
Ensembl chr20:18,335,862...18,377,022
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G |
Slc25a11 |
solute carrier family 25 member 11 |
decreases expression |
EXP |
Oleic Acid results in decreased expression of SLC25A11 mRNA |
CTD |
PMID:24349266 |
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NCBI chr10:55,856,209...55,859,060
Ensembl chr10:55,357,597...55,360,410
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G |
Slc25a20 |
solute carrier family 25 member 20 |
increases expression multiple interactions |
EXP ISO |
Oleic Acid results in increased expression of SLC25A20 protein [Farnesol analog co-treated with Oleic Acid] results in increased expression of SLC25A20 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of SLC25A20 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of SLC25A20 mRNA |
CTD |
PMID:24349266 PMID:30611723 |
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NCBI chr 8:118,243,573...118,265,027
Ensembl chr 8:109,365,002...109,386,512
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G |
Slc25a22 |
solute carrier family 25 member 22 |
decreases expression |
EXP |
Oleic Acid results in decreased expression of SLC25A22 mRNA |
CTD |
PMID:24349266 |
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NCBI chr 1:205,954,713...205,966,188
Ensembl chr 1:196,528,472...196,536,331
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G |
Slc27a1 |
solute carrier family 27 member 1 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of SLC27A1 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of SLC27A1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of SLC27A1 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of SLC27A1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr16:18,311,859...18,337,024
Ensembl chr16:18,278,984...18,296,063
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G |
Slc27a2 |
solute carrier family 27 member 2 |
multiple interactions increases expression |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of SLC27A2 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of SLC27A2 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of SLC27A2 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of SLC27A2 mRNA; Tamoxifen promotes the reaction [Oleic Acid results in increased expression of SLC27A2 mRNA] |
CTD |
PMID:30611723 PMID:38092172 PMID:38191086 |
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NCBI chr 3:134,258,101...134,295,581
Ensembl chr 3:113,804,728...113,842,208
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G |
Slc27a4 |
solute carrier family 27 member 4 |
multiple interactions |
ISO |
PPARA protein promotes the reaction [Oleic Acid results in increased expression of SLC27A4 mRNA] |
CTD |
PMID:18489776 |
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NCBI chr 3:33,472,903...33,485,824
Ensembl chr 3:13,075,022...13,087,943
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G |
Slc2a1 |
solute carrier family 2 member 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SLC2A1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:132,717,196...132,745,416
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G |
Slc2a2 |
solute carrier family 2 member 2 |
increases expression multiple interactions |
ISO |
Oleic Acid results in increased expression of SLC2A2 mRNA [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of SLC2A2 mRNA; Bezafibrate inhibits the reaction [Oleic Acid results in increased expression of SLC2A2 mRNA] |
CTD |
PMID:12048068 PMID:30547786 |
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NCBI chr 2:113,537,884...113,568,422
Ensembl chr 2:111,611,774...111,639,933
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G |
Slc6a3 |
solute carrier family 6 member 3 |
multiple interactions |
ISO |
PPARA protein promotes the reaction [Oleic Acid results in increased expression of SLC6A3 mRNA] |
CTD |
PMID:18489776 |
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NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:29,709,443...29,750,413
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G |
Smim20 |
small integral membrane protein 20 |
increases expression |
ISO |
Oleic Acid results in increased expression of SMIM20 mRNA |
CTD |
PMID:30524225 |
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NCBI chr14:61,924,155...61,935,630
Ensembl chr14:57,711,307...57,722,681
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G |
Snap23 |
synaptosome associated protein 23 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SNAP23 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SNAP23 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 3:127,966,184...127,999,929
Ensembl chr 3:107,514,131...107,544,320
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G |
Socs1 |
suppressor of cytokine signaling 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SOCS1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr10:5,389,574...5,391,265
Ensembl chr10:4,882,560...4,884,383
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G |
Socs2 |
suppressor of cytokine signaling 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SOCS2 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SOCS2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 7:31,890,564...31,932,092
Ensembl chr 7:30,008,578...30,043,548
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G |
Socs3 |
suppressor of cytokine signaling 3 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SOCS3 mRNA |
CTD |
PMID:30547786 |
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NCBI chr10:103,692,579...103,695,975
Ensembl chr10:103,193,537...103,197,787
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G |
Sod1 |
superoxide dismutase 1 |
multiple interactions decreases secretion decreases expression |
ISO |
Diethylhexyl Phthalate promotes the reaction [Oleic Acid results in decreased secretion of SOD1 protein]; gastrodin inhibits the reaction [Oleic Acid results in decreased expression of SOD1 mRNA] |
CTD |
PMID:26634892 PMID:27996362 |
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NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249
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G |
Sod2 |
superoxide dismutase 2 |
increases expression multiple interactions |
EXP ISO |
Oleic Acid results in increased expression of SOD2 mRNA [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SOD2 mRNA |
CTD |
PMID:24349266 PMID:30547786 |
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NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189
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G |
Sqstm1 |
sequestosome 1 |
increases expression multiple interactions |
ISO |
Oleic Acid results in increased expression of SQSTM1 protein [[Palmitic Acid co-treated with Oleic Acid] results in increased abundance of Fatty Acids, Nonesterified] which results in increased expression of SQSTM1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SQSTM1 protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of SQSTM1 protein]; lactucin inhibits the reaction [[[Palmitic Acid co-treated with Oleic Acid] results in increased abundance of Fatty Acids, Nonesterified] which results in increased expression of SQSTM1 mRNA]; Metformin inhibits the reaction [Oleic Acid results in increased expression of SQSTM1 protein]; necrostatin-1 inhibits the reaction [Oleic Acid results in increased expression of SQSTM1 protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased expression of SQSTM1 protein]; qidan inhibits the reaction [Oleic Acid results in increased expression of SQSTM1 protein] |
CTD |
PMID:36055749 PMID:36273635 PMID:36592823 PMID:36905866 |
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NCBI chr10:35,026,598...35,037,750
Ensembl chr10:34,525,519...34,536,673
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
increases expression multiple interactions decreases expression |
EXP ISO |
Oleic Acid results in increased expression of SREBF1 mRNA Oleic Acid results in increased expression of SREBF1 mRNA; Oleic Acid results in increased expression of SREBF1 protein [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride co-treated with Oleic Acid] results in increased expression of SREBF1 mRNA [Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in increased expression of SREBF1 protein; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA]; sophocarpine inhibits the reaction [Oleic Acid results in increased expression of SREBF1 mRNA] [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of SREBF1 mRNA; [cyhalothrin co-treated with Oleic Acid] results in increased expression of SREBF1 protein; [GW 4064 co-treated with Oleic Acid] results in decreased expression of SREBF1 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of SREBF1 mRNA; [Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of SREBF1 mRNA; [Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of SREBF1 protein; [Oleic Acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SREBF1 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SREBF1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SREBF1 protein; Benzo(a)pyrene inhibits the reaction [Estradiol inhibits the reaction [Oleic Acid results in increased expression of SREBF1 mRNA]]; Benzo(a)pyrene inhibits the reaction [Estradiol inhibits the reaction [Oleic Acid results in increased expression of SREBF1 protein]]; Cholecalciferol inhibits the reaction [Tamoxifen promotes the reaction [Oleic Acid results in increased expression of SREBF1 mRNA]]; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA]; Dibutyl Phthalate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA]; Diethylhexyl Phthalate promotes the reaction [Oleic Acid results in increased expression of SREBF1 protein]; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of SREBF1 mRNA]; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of SREBF1 protein]; Estradiol inhibits the reaction [Oleic Acid results in increased expression of SREBF1 mRNA]; Estradiol inhibits the reaction [Oleic Acid results in increased expression of SREBF1 protein]; GW 6471 inhibits the reaction [[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of SREBF1 protein]; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 protein]; Metformin inhibits the reaction [[cyhalothrin co-treated with Oleic Acid] results in increased expression of SREBF1 protein]; Plant Extracts inhibits the reaction [Oleic Acid results in decreased expression of SREBF1 mRNA]; Plant Extracts inhibits the reaction [Oleic Acid results in decreased expression of SREBF1 protein]; Tamoxifen promotes the reaction [Oleic Acid results in increased expression of SREBF1 mRNA]; VDR protein affects the reaction [Tamoxifen promotes the reaction [Oleic Acid results in increased expression of SREBF1 mRNA]] Oleic Acid results in decreased expression of SREBF1 mRNA; Oleic Acid results in decreased expression of SREBF1 protein |
CTD |
PMID:15949695 PMID:23395669 PMID:23603006 PMID:26190035 PMID:26854922 PMID:27996362 PMID:30165350 PMID:30611723 PMID:31730885 PMID:33508418 PMID:36347319 PMID:36529352 PMID:36905866 PMID:38092172 PMID:38103844 PMID:38191086 More...
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NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,007,637...45,029,650
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G |
Tbxa2r |
thromboxane A2 receptor |
multiple interactions |
EXP |
Phenolsulfonphthalein inhibits the reaction [Oleic Acid results in increased expression of TBXA2R mRNA] |
CTD |
PMID:11263294 |
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NCBI chr 7:9,034,077...9,041,489
Ensembl chr 7:8,383,378...8,388,176
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G |
Tecr |
trans-2,3-enoyl-CoA reductase |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of TECR mRNA |
CTD |
PMID:30611723 |
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NCBI chr19:41,431,422...41,472,880
Ensembl chr19:24,541,615...24,568,168
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G |
Tfam |
transcription factor A, mitochondrial |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of TFAM mRNA; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of TFAM mRNA] |
CTD |
PMID:26847930 |
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NCBI chr20:17,355,373...17,367,422
Ensembl chr20:17,356,197...17,368,292
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G |
Tfrc |
transferrin receptor |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in increased expression of TFRC protein; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of TFRC protein] |
CTD |
PMID:32976958 |
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NCBI chr11:81,668,478...81,690,318
Ensembl chr11:68,163,413...68,185,257
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions increases expression |
ISO |
Sorafenib inhibits the reaction [Oleic Acid results in increased expression of TGFB1 protein] |
CTD |
PMID:32918399 |
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NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847
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G |
Tgfb2 |
transforming growth factor, beta 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TGFB2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr13:100,691,540...100,793,227
Ensembl chr13:98,160,087...98,261,405
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G |
Thrsp |
thyroid hormone responsive |
multiple interactions decreases expression |
ISO |
Bezafibrate promotes the reaction [Oleic Acid results in decreased expression of THRSP mRNA]; Fenofibrate promotes the reaction [Oleic Acid results in decreased expression of THRSP mRNA] |
CTD |
PMID:24534255 |
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NCBI chr 1:161,134,640...161,138,964
Ensembl chr 1:151,723,086...151,728,075
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G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
multiple interactions increases expression |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TIMP1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of TIMP1 mRNA; Sorafenib inhibits the reaction [Oleic Acid results in increased expression of TIMP1 mRNA] |
CTD |
PMID:26187275 PMID:30547786 PMID:32918399 |
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NCBI chr X:3,766,509...3,772,578
Ensembl chr X:1,212,972...1,217,664
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G |
Tnf |
tumor necrosis factor |
decreases response to substance increases expression multiple interactions |
ISO EXP |
Oleic Acid results in decreased susceptibility to TNF protein Oleic Acid results in increased expression of TNF mRNA; Oleic Acid results in increased expression of TNF protein [Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein]]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein] [Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein; Dexamethasone inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]; Dexamethasone inhibits the reaction [Oleic Acid results in increased expression of TNF protein]; gossypin inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]; gossypin inhibits the reaction [Oleic Acid results in increased expression of TNF protein]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein] [Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ABCA1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ACSL1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AGPAT2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AGPAT5 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AHR mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ARG1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of B4GALT5 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CAT mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CXCL2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CXCL3 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of DYNC1H1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of DYNC1I1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ENO3 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ERLIN1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of FOXA1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of GLUD1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of GLUD2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of HSDL2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of IL1A mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of LAMB1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of NR1H4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PEBP1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PKLR mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PLD1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PNPLA3 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PPARD mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PRKAA1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RAB18 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RHEB mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RHOB mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SCD mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SERPINE1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SLC2A1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SOCS1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SOD2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TGFB2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TNFAIP2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TUBB2A mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of UGCG mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of VAMP4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of VCAN mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in decreased expression of CPT1A protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in decreased expression of DST mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ACSL4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ANGPTL4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ANXA2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CIDEC protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CPT1A mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CXCL8 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CYP24A1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CYP26A1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of FGF21 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of FLOT1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of HIF1A protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of HILPDA protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of JAK1 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of LDLR mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MAP3K8 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MAP4K4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MTTP mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PDK4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PDK4 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PLIN2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PLIN2 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PPARA mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ROCK2 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SNAP23 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SOCS2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SOCS3 mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF mRNA]; dorsomorphin inhibits the reaction [gastrodin inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]]; gastrodin inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]; Quercetin inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]; Quercetin inhibits the reaction [Oleic Acid results in increased expression of TNF protein]; Silymarin inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]; Silymarin inhibits the reaction [Oleic Acid results in increased expression of TNF protein]; Sorafenib inhibits the reaction [Oleic Acid results in increased expression of TNF protein]; Vitamin E inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]; Vitamin E inhibits the reaction [Oleic Acid results in increased expression of TNF protein] |
CTD |
PMID:22683933 PMID:23348005 PMID:26190035 PMID:26634892 PMID:30547786 PMID:32918399 PMID:37009739 PMID:37696682 PMID:38103844 More...
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NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
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G |
Tnfaip2 |
TNF alpha induced protein 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TNFAIP2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 6:136,297,388...136,311,106
Ensembl chr 6:130,476,889...130,489,914
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G |
Tp53 |
tumor protein p53 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of TP53 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of TP53 mRNA |
CTD |
PMID:32369900 |
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NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524
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G |
Trpv1 |
transient receptor potential cation channel, subfamily V, member 1 |
multiple interactions |
ISO |
Oleic Acid inhibits the reaction [Particulate Matter results in increased expression of and results in increased phosphorylation of TRPV1 protein] |
CTD |
PMID:38456238 |
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NCBI chr10:58,349,936...58,375,021
Ensembl chr10:57,851,428...57,876,513
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G |
Tubb2a |
tubulin, beta 2A class IIa |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TUBB2A mRNA |
CTD |
PMID:30547786 |
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NCBI chr17:31,002,186...31,006,057
Ensembl chr17:30,747,503...30,800,714
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G |
Tufm |
Tu translation elongation factor, mitochondrial |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of TUFM mRNA |
CTD |
PMID:30547786 |
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NCBI chr 1:190,504,373...190,507,980
Ensembl chr 1:181,073,788...181,077,395
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G |
Ucp2 |
uncoupling protein 2 |
increases expression multiple interactions decreases expression |
EXP |
Oleic Acid results in increased expression of UCP2 mRNA [Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in decreased expression of UCP2 protein; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of UCP2 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 protein; tetrabromobisphenol A promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 mRNA]; tetrabromobisphenol A promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 protein]; Triiodothyronine promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 mRNA]; Triiodothyronine promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 protein] Oleic Acid results in decreased expression of UCP2 mRNA |
CTD |
PMID:11341955 PMID:12588052 PMID:24349266 PMID:25048947 PMID:26854922 |
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NCBI chr 1:164,251,373...164,257,742
Ensembl chr 1:154,839,209...154,845,611
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G |
Ucp3 |
uncoupling protein 3 |
increases expression multiple interactions |
EXP ISO |
Oleic Acid results in increased expression of UCP3 mRNA Oleic Acid inhibits the reaction [troglitazone results in decreased expression of UCP3 mRNA] |
CTD |
PMID:11056218 PMID:12630940 |
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NCBI chr 1:164,227,910...164,240,893
Ensembl chr 1:154,815,777...154,828,762
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G |
Ugcg |
UDP-glucose ceramide glucosyltransferase |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of UGCG mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of UGCG mRNA |
CTD |
PMID:30547786 |
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NCBI chr 5:78,828,006...78,860,725
Ensembl chr 5:74,032,978...74,065,393
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G |
Vamp4 |
vesicle-associated membrane protein 4 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of VAMP4 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of VAMP4 mRNA |
CTD |
PMID:30547786 |
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NCBI chr13:77,453,135...77,475,909
Ensembl chr13:74,919,880...74,933,686
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G |
Vcan |
versican |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of VCAN mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of VCAN mRNA |
CTD |
PMID:30547786 |
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NCBI chr 2:22,497,035...22,595,955
Ensembl chr 2:20,761,718...20,860,637
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G |
Vdr |
vitamin D receptor |
multiple interactions |
ISO |
VDR protein affects the reaction [Tamoxifen promotes the reaction [Oleic Acid results in increased expression of SREBF1 mRNA]] |
CTD |
PMID:38191086 |
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NCBI chr 7:130,864,764...130,916,757
Ensembl chr 7:128,987,981...129,037,677
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G |
Vnn1 |
vanin 1 |
multiple interactions |
ISO |
Oleic Acid promotes the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of VNN1 mRNA] |
CTD |
PMID:31340670 |
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NCBI chr 1:23,356,324...23,366,629
Ensembl chr 1:21,537,094...21,547,395
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G |
Xbp1 |
X-box binding protein 1 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased splicing of XBP1 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased splicing of XBP1 mRNA Oleic Acid inhibits the reaction [[Palmitates co-treated with bisphenol A] results in increased splicing of XBP1 mRNA] |
CTD |
PMID:32369900 PMID:32976987 |
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NCBI chr14:84,604,623...84,609,707
Ensembl chr14:80,390,643...80,395,693
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G |
Yap1 |
Yes1 associated transcriptional regulator |
affects localization |
ISO |
Oleic Acid affects the localization of YAP1 protein |
CTD |
PMID:37117602 |
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NCBI chr 8:13,380,551...13,451,640
Ensembl chr 8:5,095,722...5,167,010
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G |
Lipc |
lipase C, hepatic type |
multiple interactions decreases abundance |
ISO |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of 1-stearoyl-2-oleoyl-sn-glycerol LIPC gene mutant form results in decreased abundance of 1-stearoyl-2-oleoyl-sn-glycerol |
CTD |
PMID:24777581 |
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NCBI chr 8:80,390,470...80,516,463
Ensembl chr 8:71,509,635...71,635,464
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G |
Lipg |
lipase G, endothelial type |
decreases abundance multiple interactions |
ISO |
LIPG gene mutant form results in decreased abundance of 1-stearoyl-2-oleoyl-sn-glycerol [LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of 1-stearoyl-2-oleoyl-sn-glycerol |
CTD |
PMID:24777581 |
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NCBI chr18:70,790,077...70,811,259
Ensembl chr18:68,514,923...68,536,260
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G |
Lipc |
lipase C, hepatic type |
decreases abundance |
ISO |
LIPC gene mutant form results in decreased abundance of 1-palmitoyl-2-oleoyl-sn-glycerol |
CTD |
PMID:24777581 |
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NCBI chr 8:80,390,470...80,516,463
Ensembl chr 8:71,509,635...71,635,464
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G |
Lipg |
lipase G, endothelial type |
decreases abundance |
ISO |
LIPG gene mutant form results in decreased abundance of 1-palmitoyl-2-oleoyl-sn-glycerol |
CTD |
PMID:24777581 |
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NCBI chr18:70,790,077...70,811,259
Ensembl chr18:68,514,923...68,536,260
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G |
Fabp1 |
fatty acid binding protein 1 |
affects abundance |
ISO |
FABP1 protein affects the abundance of 2-oleoylglycerol |
CTD |
PMID:29414765 |
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NCBI chr 4:104,744,302...104,753,119
Ensembl chr 4:103,191,006...103,194,788
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G |
Mgll |
monoglyceride lipase |
increases degradation multiple interactions |
EXP |
MGLL protein results in increased degradation of 2-oleoylglycerol Nitroglycerin promotes the reaction [MGLL protein results in increased degradation of 2-oleoylglycerol] |
CTD |
PMID:19515121 |
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NCBI chr 4:122,749,436...122,851,440
Ensembl chr 4:121,192,195...121,294,179
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G |
Pafah1b1 |
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 |
increases expression multiple interactions |
EXP |
Castor Oil results in increased expression of PAFAH1B1 protein isosorbide-5-mononitrate inhibits the reaction [Castor Oil results in increased expression of PAFAH1B1 protein] |
CTD |
PMID:1354728 PMID:2743081 PMID:8738301 |
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NCBI chr10:60,031,441...60,090,259
Ensembl chr10:59,534,117...59,591,808
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G |
Lipc |
lipase C, hepatic type |
multiple interactions |
ISO |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of cholesteryl oleate |
CTD |
PMID:24777581 |
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NCBI chr 8:80,390,470...80,516,463
Ensembl chr 8:71,509,635...71,635,464
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G |
Lipg |
lipase G, endothelial type |
multiple interactions increases abundance |
ISO |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of cholesteryl oleate LIPG gene mutant form results in increased abundance of cholesteryl oleate |
CTD |
PMID:24777581 |
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NCBI chr18:70,790,077...70,811,259
Ensembl chr18:68,514,923...68,536,260
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G |
Abcg8 |
ATP binding cassette subfamily G member 8 |
affects expression |
EXP |
Corn Oil affects the expression of ABCG8 mRNA |
CTD |
PMID:16360708 |
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NCBI chr 6:15,698,448...15,717,730
Ensembl chr 6:9,945,629...9,964,912
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G |
Acaca |
acetyl-CoA carboxylase alpha |
increases expression |
EXP |
Corn Oil results in increased expression of ACACA mRNA |
CTD |
PMID:1973097 |
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NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,014,170...69,276,457
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G |
Acly |
ATP citrate lyase |
affects expression |
EXP |
Corn Oil affects the expression of ACLY mRNA |
CTD |
PMID:16360708 |
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NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,412,049...85,463,320
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G |
Acot2 |
acyl-CoA thioesterase 2 |
affects expression |
EXP |
Corn Oil affects the expression of ACOT2 mRNA |
CTD |
PMID:16360708 |
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NCBI chr 6:109,341,426...109,352,818
Ensembl chr 6:103,611,544...103,619,245
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
multiple interactions |
EXP |
Corn Oil promotes the reaction [Glucose results in increased expression of ADIPOQ protein] |
CTD |
PMID:29165388 |
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NCBI chr11:91,226,524...91,240,244
Ensembl chr11:77,721,912...77,735,564
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G |
Akr1b7 |
aldo-keto reductase family 1, member B7 |
affects expression |
EXP |
Corn Oil affects the expression of AKR1B7 mRNA |
CTD |
PMID:16360708 |
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NCBI chr 4:64,043,901...64,083,751
Ensembl chr 4:63,076,800...63,089,502
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G |
Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
affects expression |
EXP |
Corn Oil affects the expression of ALDH1A1 mRNA |
CTD |
PMID:16360708 |
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NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:218,042,127...218,152,961
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G |
Angptl4 |
angiopoietin-like 4 |
affects expression |
EXP |
Corn Oil affects the expression of ANGPTL4 mRNA |
CTD |
PMID:16360708 |
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NCBI chr 7:15,252,450...15,259,971
Ensembl chr 7:14,550,311...14,556,519
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G |
Areg |
amphiregulin |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of AREG mRNA |
CTD |
PMID:32186404 |
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NCBI chr14:17,256,384...17,265,641
Ensembl chr14:16,972,187...16,981,535
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G |
Bad |
BCL2-associated agonist of cell death |
increases expression |
EXP |
Corn Oil results in increased expression of BAD mRNA |
CTD |
PMID:22760963 |
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NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:204,131,501...204,142,823
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G |
Bdkrb1 |
bradykinin receptor B1 |
multiple interactions |
EXP |
Corn Oil inhibits the reaction [Glucose results in increased expression of BDKRB1 protein] |
CTD |
PMID:29165388 |
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NCBI chr 6:130,275,631...130,284,968
Ensembl chr 6:124,510,870...124,513,747
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G |
Bhlhe40 |
basic helix-loop-helix family, member e40 |
affects expression |
EXP |
Corn Oil affects the expression of BHLHE40 mRNA |
CTD |
PMID:16360708 |
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NCBI chr 4:143,174,450...143,180,150
Ensembl chr 4:141,618,476...141,624,774
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G |
Bhmt |
betaine-homocysteine S-methyltransferase |
affects expression |
EXP |
Corn Oil affects the expression of BHMT mRNA |
CTD |
PMID:16360708 |
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NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:24,859,873...24,879,742
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G |
Birc3 |
baculoviral IAP repeat-containing 3 |
increases expression |
ISO |
Corn Oil results in increased expression of BIRC3 mRNA |
CTD |
PMID:33263755 |
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NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:5,000,845...5,015,802
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G |
Bmp1 |
bone morphogenetic protein 1 |
affects expression |
EXP |
Corn Oil affects the expression of BMP1 mRNA |
CTD |
PMID:16360708 |
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NCBI chr15:51,961,310...52,005,597
Ensembl chr15:45,551,603...45,595,776
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G |
Bmp2 |
bone morphogenetic protein 2 |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of BMP2 mRNA |
CTD |
PMID:32186404 |
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NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:120,812,882...120,821,397
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G |
Cadm1 |
cell adhesion molecule 1 |
affects expression |
EXP |
Corn Oil affects the expression of CADM1 mRNA |
CTD |
PMID:16360708 |
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NCBI chr 8:56,744,374...57,075,264
Ensembl chr 8:47,847,325...48,182,833
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G |
Calca |
calcitonin-related polypeptide alpha |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of CALCA mRNA |
CTD |
PMID:32186404 |
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NCBI chr 1:178,312,636...178,317,588
Ensembl chr 1:168,878,214...168,883,105
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G |
Car6 |
carbonic anhydrase 6 |
increases expression |
ISO |
Corn Oil results in increased expression of CAR6 mRNA |
CTD |
PMID:33263755 |
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NCBI chr 5:165,941,028...165,959,566
Ensembl chr 5:160,658,105...160,676,644
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G |
Card9 |
caspase recruitment domain family, member 9 |
increases expression |
ISO |
Corn Oil results in increased expression of CARD9 mRNA |
CTD |
PMID:33263755 |
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NCBI chr 3:29,569,907...29,578,402
Ensembl chr 3:9,171,815...9,180,237
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G |
Cat |
catalase |
multiple interactions decreases expression |
ISO |
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in decreased expression of CAT protein Corn Oil results in decreased expression of CAT protein |
CTD |
PMID:36432690 |
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NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
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G |
Cav3 |
caveolin 3 |
decreases expression |
ISO |
Corn Oil results in decreased expression of CAV3 mRNA |
CTD |
PMID:33263755 |
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NCBI chr 4:147,137,993...147,153,967
Ensembl chr 4:145,582,060...145,598,137
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
increases expression decreases expression |
ISO EXP |
Corn Oil results in increased expression of CCL3 mRNA Corn Oil results in decreased expression of CCL3 mRNA |
CTD |
PMID:22760963 PMID:23409006 |
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NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,451,388...68,452,938
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G |
Ccnd1 |
cyclin D1 |
affects expression |
EXP |
Corn Oil affects the expression of CCND1 mRNA |
CTD |
PMID:16360708 |
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NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602
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G |
Cd36 |
CD36 molecule |
decreases expression |
EXP |
Corn Oil results in decreased expression of CD36 mRNA |
CTD |
PMID:22760963 |
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NCBI chr 4:18,209,088...18,302,142
Ensembl chr 4:17,354,466...17,513,903
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G |
Cdhr1 |
cadherin-related family member 1 |
increases expression |
EXP |
Corn Oil results in increased expression of CDHR1 mRNA |
CTD |
PMID:22760963 |
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NCBI chr16:12,863,696...12,883,579
Ensembl chr16:12,843,437...12,863,396
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
affects expression increases expression |
EXP |
Corn Oil affects the expression of CDKN1A mRNA Corn Oil results in increased expression of CDKN1A mRNA |
CTD |
PMID:16360708 PMID:22760963 |
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NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585
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G |
Cenpt |
centromere protein T |
increases expression |
EXP |
Corn Oil results in increased expression of CENPT mRNA |
CTD |
PMID:22760963 |
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NCBI chr19:50,644,548...50,651,048
Ensembl chr19:33,734,685...33,741,142
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G |
Cfb |
complement factor B |
increases expression |
EXP |
Corn Oil results in increased expression of CFB mRNA |
CTD |
PMID:22760963 |
|
NCBI chr20:3,975,271...3,981,138
Ensembl chr20:3,951,474...3,976,505
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G |
Cldn1 |
claudin 1 |
decreases expression |
ISO |
Corn Oil results in decreased expression of CLDN1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr11:87,926,376...87,941,533
Ensembl chr11:74,421,569...74,436,724
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G |
Cldn9 |
claudin 9 |
increases expression |
ISO |
Corn Oil results in increased expression of CLDN9 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr10:13,218,728...13,220,159
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G |
Cox7a1 |
cytochrome c oxidase subunit 7A1 |
decreases expression |
ISO |
Corn Oil results in decreased expression of COX7A1 mRNA |
CTD |
PMID:23409006 |
|
NCBI chr 1:94,549,663...94,572,330
Ensembl chr 1:85,441,871...85,445,151
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G |
Cpt1a |
carnitine palmitoyltransferase 1A |
increases expression multiple interactions affects expression |
EXP ISO |
Corn Oil results in increased expression of CPT1A mRNA [bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of CPT1A mRNA Corn Oil affects the expression of CPT1A mRNA |
CTD |
PMID:16360708 PMID:22760963 PMID:36432690 |
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NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:200,565,613...200,627,055
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G |
Cpt2 |
carnitine palmitoyltransferase 2 |
multiple interactions |
ISO |
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of CPT2 mRNA |
CTD |
PMID:36432690 |
|
NCBI chr 5:127,893,450...127,911,347
Ensembl chr 5:122,664,677...122,682,095
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G |
Crot |
carnitine O-octanoyltransferase |
affects expression multiple interactions |
EXP ISO |
Corn Oil affects the expression of CROT mRNA [bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of CROT mRNA |
CTD |
PMID:16360708 PMID:36432690 |
|
NCBI chr 4:26,031,729...26,088,057
Ensembl chr 4:25,080,587...25,133,109
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G |
Ctsg |
cathepsin G |
increases expression |
EXP |
Corn Oil results in increased expression of CTSG mRNA |
CTD |
PMID:22760963 |
|
NCBI chr15:33,901,230...33,907,596
Ensembl chr15:29,931,003...29,937,353
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G |
Cyp17a1 |
cytochrome P450, family 17, subfamily a, polypeptide 1 |
affects expression |
EXP |
Corn Oil affects the expression of CYP17A1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:245,535,462...245,541,573
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G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
affects expression |
EXP |
Corn Oil affects the expression of CYP7A1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:19,376,974...19,386,688
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G |
Cyp8b1 |
cytochrome P450 family 8 subfamily B member 1 |
affects expression |
EXP |
Corn Oil affects the expression of CYP8B1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 8:130,455,622...130,457,592
Ensembl chr 8:121,557,062...121,580,166
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G |
Ephx2 |
epoxide hydrolase 2 |
affects expression |
EXP |
Corn Oil affects the expression of EPHX2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr15:44,465,447...44,503,157
Ensembl chr15:40,289,902...40,327,615
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G |
Ets1 |
ETS proto-oncogene 1, transcription factor |
decreases expression |
EXP |
Corn Oil results in decreased expression of ETS1 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 8:39,303,936...39,426,022
Ensembl chr 8:31,045,945...31,168,010
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G |
Fabp1 |
fatty acid binding protein 1 |
multiple interactions |
EXP |
[Ethanol co-treated with Corn Oil] results in decreased expression of FABP1 mRNA |
CTD |
PMID:15016835 |
|
NCBI chr 4:104,744,302...104,753,119
Ensembl chr 4:103,191,006...103,194,788
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G |
Fabp2 |
fatty acid binding protein 2 |
affects expression |
EXP |
Corn Oil affects the expression of FABP2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 2:213,724,629...213,728,686
Ensembl chr 2:211,040,032...211,044,089
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G |
Fabp7 |
fatty acid binding protein 7 |
affects expression |
EXP |
Corn Oil affects the expression of FABP7 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr20:37,667,125...37,673,299
Ensembl chr20:37,123,193...37,126,880
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G |
Fasn |
fatty acid synthase |
affects expression |
EXP |
Corn Oil affects the expression of FASN mRNA |
CTD |
PMID:16360708 |
|
NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261
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G |
Fcgrt |
Fc gamma receptor and transporter |
decreases expression |
EXP |
Corn Oil results in decreased expression of FCGRT mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 1:104,710,902...104,720,685
Ensembl chr 1:95,567,175...95,584,084
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G |
Fgb |
fibrinogen beta chain |
affects expression |
EXP |
Corn Oil affects the expression of FGB mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:168,394,916...168,405,979
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G |
Fgf21 |
fibroblast growth factor 21 |
affects expression |
EXP |
Corn Oil affects the expression of FGF21 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:105,219,825...105,221,376
Ensembl chr 1:96,083,441...96,090,454
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G |
Fst |
follistatin |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of FST mRNA |
CTD |
PMID:32186404 |
|
NCBI chr 2:47,856,345...47,863,670
Ensembl chr 2:46,123,439...46,130,571
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G |
G0s2 |
G0/G1switch 2 |
affects expression |
EXP |
Corn Oil affects the expression of G0S2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr13:107,335,036...107,335,948
Ensembl chr13:104,806,156...104,807,451
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G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
affects expression |
EXP |
Corn Oil affects the expression of GADD45A mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:96,154,789...96,157,115
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G |
Gal |
galanin and GMAP prepropeptide |
increases expression |
EXP |
Corn Oil results in increased expression of GAL mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 1:210,079,709...210,084,572
Ensembl chr 1:200,650,439...200,654,959
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G |
Gck |
glucokinase |
affects expression |
EXP |
Corn Oil affects the expression of GCK mRNA |
CTD |
PMID:16360708 |
|
NCBI chr14:84,999,019...85,041,098
Ensembl chr14:80,785,060...80,826,995
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G |
Gjd2 |
gap junction protein, delta 2 |
increases expression |
ISO |
Corn Oil results in increased expression of GJD2 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 3:121,226,372...121,229,367
Ensembl chr 3:100,772,062...100,775,061
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G |
Got1 |
glutamic-oxaloacetic transaminase 1 |
affects expression |
EXP |
Corn Oil affects the expression of GOT1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:242,357,306...242,380,633
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G |
Got2 |
glutamic-oxaloacetic transaminase 2 |
decreases expression |
EXP |
Corn Oil results in decreased expression of GOT2 mRNA |
CTD |
PMID:34987138 |
|
NCBI chr19:9,180,428...9,206,113
Ensembl chr19:9,174,311...9,199,994
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G |
Gpd2 |
glycerol-3-phosphate dehydrogenase 2 |
affects expression |
EXP |
Corn Oil affects the expression of GPD2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 3:62,209,432...62,346,590
Ensembl chr 3:41,801,930...41,936,901
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G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions |
EXP |
[Corn Oil co-treated with (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid] results in increased activity of GPT protein; Dactinomycin inhibits the reaction [[Corn Oil co-treated with (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid] results in increased activity of GPT protein]; Orlistat inhibits the reaction [[Corn Oil co-treated with (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid] results in increased activity of GPT protein] |
CTD |
PMID:29479035 |
|
NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:108,416,642...108,419,494
|
|
G |
H2ac25 |
H2A clustered histone 25 |
affects expression |
EXP |
Corn Oil affects the expression of H2A mRNA |
CTD |
PMID:16360708 |
|
NCBI chr10:44,233,283...44,234,835
Ensembl chr10:43,733,668...43,744,874
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G |
Hal |
histidine ammonia lyase |
affects expression |
EXP |
Corn Oil affects the expression of HAL mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 7:29,894,495...29,924,744
Ensembl chr 7:28,006,972...28,037,701
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G |
Hamp |
hepcidin antimicrobial peptide |
affects expression |
EXP |
Corn Oil affects the expression of HAMP mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:86,170,901...86,172,891
|
|
G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
affects expression |
EXP |
Corn Oil affects the expression of HMGCR mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:27,997,525...28,019,703
|
|
G |
Hoxa11 |
homeobox A11 |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of HOXA11 mRNA |
CTD |
PMID:32186404 |
|
NCBI chr 4:82,673,139...82,676,801
Ensembl chr 4:81,342,528...81,346,232
|
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G |
Hp |
haptoglobin |
increases expression |
EXP |
Corn Oil results in increased expression of HP mRNA |
CTD |
PMID:22760963 |
|
NCBI chr19:54,449,151...54,453,701
Ensembl chr19:37,539,627...37,544,523
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G |
Hsp90aa1 |
heat shock protein 90 alpha family class A member 1 |
increases expression |
ISO |
Corn Oil results in increased expression of HSP90AA1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:129,702,383...129,707,268
|
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G |
Idi1 |
isopentenyl-diphosphate delta isomerase 1 |
affects expression |
EXP |
Corn Oil affects the expression of IDI1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr17:66,539,761...66,547,524
Ensembl chr17:61,629,594...61,637,357
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G |
Igf2bp2 |
insulin-like growth factor 2 mRNA binding protein 2 |
affects expression increases expression |
EXP |
Corn Oil affects the expression of IGF2BP2 mRNA Corn Oil results in increased expression of IGF2BP2 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr11:92,378,908...92,478,893
Ensembl chr11:78,874,414...78,974,377
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G |
Igfbp1 |
insulin-like growth factor binding protein 1 |
affects expression |
EXP |
Corn Oil affects the expression of IGFBP1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr14:86,261,277...86,266,344
Ensembl chr14:82,047,415...82,052,482
|
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G |
Ihh |
Indian hedgehog signaling molecule |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of IHH mRNA |
CTD |
PMID:32186404 |
|
NCBI chr 9:83,952,986...83,959,203
Ensembl chr 9:76,504,315...76,510,532
|
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G |
Il12b |
interleukin 12B |
increases secretion |
EXP |
Corn Oil results in increased secretion of IL12B protein |
CTD |
PMID:33263755 |
|
NCBI chr10:29,390,300...29,405,194
Ensembl chr10:28,893,008...28,902,903
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G |
Il18 |
interleukin 18 |
increases expression |
ISO |
Corn Oil results in increased expression of IL18 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:50,906,960...50,932,887
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G |
Il1a |
interleukin 1 alpha |
increases secretion |
EXP |
Corn Oil results in increased secretion of IL1A protein |
CTD |
PMID:33263755 |
|
NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
increases secretion |
EXP |
Corn Oil results in increased secretion of IL1B protein |
CTD |
PMID:33263755 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415
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G |
Il1rn |
interleukin 1 receptor antagonist |
increases expression |
EXP |
Corn Oil results in increased expression of IL1RN mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:7,111,550...7,127,445
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G |
Il4 |
interleukin 4 |
increases expression increases secretion decreases expression |
ISO EXP |
Corn Oil results in increased expression of IL4 mRNA Corn Oil results in increased secretion of IL4 protein Corn Oil results in decreased expression of IL4 mRNA |
CTD |
PMID:23409006 PMID:33263755 |
|
NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750
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G |
Il6r |
interleukin 6 receptor |
increases expression |
EXP |
Corn Oil results in increased expression of IL6R mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:175,298,686...175,347,536
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G |
Il9 |
interleukin 9 |
increases secretion |
EXP |
Corn Oil results in increased secretion of IL9 protein |
CTD |
PMID:33263755 |
|
NCBI chr17:8,117,028...8,120,151
Ensembl chr17:8,111,772...8,114,895
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G |
Inhbe |
inhibin subunit beta E |
affects expression |
EXP |
Corn Oil affects the expression of INHBE mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 7:65,061,531...65,064,519
Ensembl chr 7:63,176,219...63,179,172
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G |
Ins1 |
insulin 1 |
multiple interactions |
EXP |
Corn Oil inhibits the reaction [Glucose results in increased expression of INS1 protein] |
CTD |
PMID:29165388 |
|
NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:251,244,973...251,245,536
|
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G |
Irak1 |
interleukin-1 receptor-associated kinase 1 |
increases expression |
ISO |
Corn Oil results in increased expression of IRAK1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr X:156,919,927...156,929,825
Ensembl chr X:151,768,777...151,778,521
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G |
Irf5 |
interferon regulatory factor 5 |
increases expression |
ISO |
Corn Oil results in increased expression of IRF5 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 4:59,092,914...59,104,596
Ensembl chr 4:58,127,640...58,139,267
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G |
Irf7 |
interferon regulatory factor 7 |
increases expression |
ISO |
Corn Oil results in increased expression of IRF7 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 1:205,796,956...205,800,543
Ensembl chr 1:196,367,361...196,370,832
|
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
Corn Oil results in increased expression of JUN mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656
|
|
G |
Klf2 |
KLF transcription factor 2 |
affects expression |
EXP |
Corn Oil affects the expression of KLF2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr16:17,555,136...17,557,768
Ensembl chr16:17,514,552...17,523,944
|
|
G |
Lcat |
lecithin cholesterol acyltransferase |
multiple interactions |
ISO |
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of LCAT mRNA |
CTD |
PMID:36432690 |
|
NCBI chr19:50,744,598...50,748,064
Ensembl chr19:33,834,403...33,838,231
|
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G |
Lcn2 |
lipocalin 2 |
increases expression |
EXP |
Corn Oil results in increased expression of LCN2 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:15,680,687...15,684,095
|
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G |
Lep |
leptin |
multiple interactions |
EXP |
Corn Oil inhibits the reaction [Glucose results in increased expression of LEP protein] |
CTD |
PMID:29165388 |
|
NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:57,661,131...57,675,262
|
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G |
Lgals1 |
galectin 1 |
increases expression |
EXP |
Corn Oil results in increased expression of LGALS1 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 7:112,365,695...112,368,801
Ensembl chr 7:110,481,392...110,488,345
|
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G |
Lox |
lysyl oxidase |
multiple interactions |
ISO |
Corn Oil results in increased activity of and results in increased cleavage of LOX protein |
CTD |
PMID:26240151 |
|
NCBI chr18:48,162,889...48,175,640
Ensembl chr18:45,967,343...46,041,477
|
|
G |
Ly75 |
lymphocyte antigen 75 |
increases expression |
EXP |
Corn Oil results in increased expression of LY75 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 3:65,173,395...65,260,878
Ensembl chr 3:44,765,122...44,852,374
|
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G |
Map2k1 |
mitogen activated protein kinase kinase 1 |
increases expression |
ISO |
Corn Oil results in increased expression of MAP2K1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:64,683,449...64,755,147
|
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G |
Map2k3 |
mitogen activated protein kinase kinase 3 |
increases expression |
ISO |
Corn Oil results in increased expression of MAP2K3 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr10:46,107,639...46,128,986
Ensembl chr10:45,607,163...45,629,492
|
|
G |
Map2k6 |
mitogen-activated protein kinase kinase 6 |
affects expression |
EXP |
Corn Oil affects the expression of MAP2K6 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr10:95,872,747...95,987,747
Ensembl chr10:95,373,204...95,488,293
|
|
G |
Map3k7 |
mitogen activated protein kinase kinase kinase 7 |
increases expression |
ISO |
Corn Oil results in increased expression of MAP3K7 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 5:51,149,524...51,212,012
Ensembl chr 5:46,357,931...46,415,597
|
|
G |
Mapk1 |
mitogen activated protein kinase 1 |
increases expression |
ISO |
Corn Oil results in increased expression of MAPK1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616
|
|
G |
Mapk14 |
mitogen activated protein kinase 14 |
increases expression |
ISO |
Corn Oil results in increased expression of MAPK14 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,749,670...6,810,589
|
|
G |
Mapk3 |
mitogen activated protein kinase 3 |
increases expression |
ISO |
Corn Oil results in increased expression of MAPK3 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863
|
|
G |
Mdm2 |
MDM2 proto-oncogene |
decreases expression |
EXP |
Corn Oil results in decreased expression of MDM2 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:53,290,664...53,314,915
|
|
G |
Mgmt |
O-6-methylguanine-DNA methyltransferase |
increases expression |
EXP |
Corn Oil results in increased expression of MGMT mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:191,710,930...191,937,756
|
|
G |
Mgst2 |
microsomal glutathione S-transferase 2 |
increases expression |
EXP |
Corn Oil results in increased expression of MGST2 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 2:137,821,787...137,866,664
Ensembl chr 2:135,693,557...135,715,828
|
|
G |
Mlycd |
malonyl-CoA decarboxylase |
decreases expression |
EXP |
Corn Oil results in decreased expression of MLYCD mRNA |
CTD |
PMID:22760963 |
|
NCBI chr19:64,356,582...64,372,447
Ensembl chr19:47,447,970...47,463,793
|
|
G |
Msmo1 |
methylsterol monooxygenase 1 |
affects expression |
EXP |
Corn Oil affects the expression of MSMO1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr16:29,747,113...29,764,360
Ensembl chr16:24,980,697...24,998,016
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G |
Mtr |
5-methyltetrahydrofolate-homocysteine methyltransferase |
multiple interactions |
ISO |
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of MTR mRNA |
CTD |
PMID:36432690 |
|
NCBI chr17:62,911,705...62,996,544
Ensembl chr17:58,220,071...58,304,822
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G |
Mx2 |
MX dynamin like GTPase 2 |
affects expression |
EXP |
Corn Oil affects the expression of MX2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr11:50,375,101...50,399,373
Ensembl chr11:36,906,111...36,930,342
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G |
Myd88 |
MYD88, innate immune signal transduction adaptor |
increases expression |
ISO |
Corn Oil results in increased expression of MYD88 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
decreases activity |
ISO |
Corn Oil results in decreased activity of NFE2L2 protein |
CTD |
PMID:30203046 |
|
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737
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G |
Nfkbia |
NFKB inhibitor alpha |
increases expression |
ISO |
Corn Oil results in increased expression of NFKBIA mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941
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G |
Nlrc4 |
NLR family, CARD domain containing 4 |
increases expression |
ISO |
Corn Oil results in increased expression of NLRC4 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 6:26,743,658...26,771,783
Ensembl chr 6:20,995,266...21,018,248
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
affects expression |
EXP |
Corn Oil affects the expression of NR1H4 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:23,846,122...23,942,047
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G |
Nr4a2 |
nuclear receptor subfamily 4, group A, member 2 |
increases expression |
EXP |
Corn Oil results in increased expression of NR4A2 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 3:62,098,739...62,115,926
Ensembl chr 3:41,689,851...41,697,877
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G |
Nsmce3 |
NSE3 homolog, SMC5-SMC6 complex component |
affects expression |
EXP |
Corn Oil affects the expression of NSMCE3 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:127,812,572...127,813,899
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G |
Oat |
ornithine aminotransferase |
affects expression |
EXP |
Corn Oil affects the expression of OAT mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:196,777,973...196,797,754
Ensembl chr 1:187,347,865...187,367,682
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G |
Osgin1 |
oxidative stress induced growth inhibitor 1 |
affects expression |
EXP |
Corn Oil affects the expression of OSGIN1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr19:64,380,336...64,409,165
Ensembl chr19:47,492,171...47,500,516
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G |
P2rx5 |
purinergic receptor P2X 5 |
affects expression |
EXP |
Corn Oil affects the expression of P2RX5 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr10:58,276,329...58,291,108
Ensembl chr10:57,777,819...57,789,423
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G |
Pax8 |
paired box 8 |
affects expression |
EXP |
Corn Oil affects the expression of PAX8 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 3:27,584,000...27,641,094
Ensembl chr 3:7,185,723...7,242,363
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G |
Pdgfa |
platelet derived growth factor subunit A |
affects expression |
EXP |
Corn Oil affects the expression of PDGFA mRNA |
CTD |
PMID:16360708 |
|
NCBI chr12:20,759,366...20,780,337
Ensembl chr12:15,645,541...15,666,497
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G |
Pdgfrb |
platelet derived growth factor receptor beta |
increases expression |
EXP |
Corn Oil results in increased expression of PDGFRB mRNA |
CTD |
PMID:22760963 |
|
NCBI chr18:56,770,348...56,809,228
Ensembl chr18:54,499,964...54,538,843
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G |
Pdlim1 |
PDZ and LIM domain 1 |
affects expression |
EXP |
Corn Oil affects the expression of PDLIM1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:248,991,818...249,040,409
Ensembl chr 1:239,042,385...239,091,076
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G |
Pdlim2 |
PDZ and LIM domain 2 |
affects expression |
EXP |
Corn Oil affects the expression of PDLIM2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr15:51,647,195...51,659,904
Ensembl chr15:45,237,477...45,249,242
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G |
Pgf |
placental growth factor |
increases expression |
EXP |
Corn Oil results in increased expression of PGF mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 6:110,547,165...110,557,747
Ensembl chr 6:104,816,104...104,826,685
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G |
Pgrmc2 |
progesterone receptor membrane component 2 |
affects expression |
EXP |
Corn Oil affects the expression of PGRMC2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 2:125,996,190...126,012,090
Ensembl chr 2:124,068,260...124,084,155
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G |
Pik3ca |
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha |
increases expression |
ISO |
Corn Oil results in increased expression of PIK3CA mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:115,174,984...115,249,032
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G |
Plin2 |
perilipin 2 |
affects expression |
EXP |
Corn Oil affects the expression of PLIN2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 5:106,202,634...106,258,748
Ensembl chr 5:101,154,411...101,242,319
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G |
Prlr |
prolactin receptor |
affects expression |
EXP |
Corn Oil affects the expression of PRLR mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 2:60,861,391...61,051,883
Ensembl chr 2:59,134,588...59,324,718
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of PTGS2 mRNA |
CTD |
PMID:32186404 |
|
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188
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G |
Ptprf |
protein tyrosine phosphatase, receptor type, F |
affects expression |
EXP |
Corn Oil affects the expression of PTPRF mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 5:137,027,376...137,109,405
Ensembl chr 5:131,742,754...131,810,023
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G |
Pycard |
PYD and CARD domain containing |
increases expression |
ISO |
Corn Oil results in increased expression of PYCARD mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:182,601,174...182,602,955
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G |
Rac1 |
Rac family small GTPase 1 |
increases expression |
ISO |
Corn Oil results in increased expression of RAC1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr12:16,150,411...16,170,864
Ensembl chr12:11,036,698...11,057,251
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G |
Ripk1 |
receptor interacting serine/threonine kinase 1 |
increases expression |
ISO |
Corn Oil results in increased expression of RIPK1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr17:31,044,983...31,077,167
Ensembl chr17:30,839,650...30,871,824
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G |
Ripk2 |
receptor-interacting serine-threonine kinase 2 |
increases expression |
ISO |
Corn Oil results in increased expression of RIPK2 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:29,631,570...29,662,657
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G |
RT1-A |
RT1 class I, locus A |
increases expression |
EXP |
Corn Oil results in increased expression of RT1-A mRNA |
CTD |
PMID:22760963 |
|
|
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G |
RT1-Bb |
RT1 class II, locus Bb |
increases expression |
EXP |
Corn Oil results in increased expression of RT1-BB mRNA |
CTD |
PMID:22760963 |
|
NCBI chr20:4,598,475...4,604,118
Ensembl chr20:4,596,559...4,607,597
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G |
RT1-CE11 |
RT1 class I, locus CE11 |
decreases expression |
EXP |
Corn Oil results in decreased expression of RT1-CE11 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr20:3,355,422...3,385,063
Ensembl chr20:3,350,937...3,380,362
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G |
RT1-CE14 |
RT1 class I, locus CE14 |
increases expression |
EXP |
Corn Oil results in increased expression of RT1-CE14 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr20:3,301,813...3,305,472
Ensembl chr20:3,297,196...3,305,134
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G |
RT1-CE15 |
RT1 class I, locus CE15 |
decreases expression |
EXP |
Corn Oil results in decreased expression of RT1-CE15 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr20:3,269,135...3,283,819
Ensembl chr20:3,264,172...3,279,563 Ensembl chr20:3,264,172...3,279,563
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G |
RT1-CE16 |
RT1 class I, locus CE16 |
increases expression |
EXP |
Corn Oil results in increased expression of RT1-CE16 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr20:3,261,656...3,265,548
Ensembl chr20:3,257,123...3,279,563
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G |
RT1-CE2 |
RT1 class I, locus CE2 |
increases expression |
EXP |
Corn Oil results in increased expression of RT1-CE2 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr20:3,542,984...3,546,753
Ensembl chr20:3,537,809...3,541,790
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G |
RT1-CE3 |
RT1 class I, locus CE3 |
increases expression |
EXP |
Corn Oil results in increased expression of RT1-CE3 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr20:3,521,323...3,525,218
Ensembl chr20:2,623,953...2,692,081
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G |
RT1-CE4 |
RT1 class I, locus CE4 |
increases expression |
EXP |
Corn Oil results in increased expression of RT1-CE4 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr20:3,436,182...3,509,236
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G |
RT1-CE5 |
RT1 class I, locus CE5 |
increases expression |
EXP |
Corn Oil results in increased expression of RT1-CE5 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr20:3,407,880...3,484,130
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G |
RT1-N1 |
RT1 class Ib, locus N1 |
decreases expression |
EXP |
Corn Oil results in decreased expression of RT1-N1 mRNA |
CTD |
PMID:22760963 |
|
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G |
S100a8 |
S100 calcium binding protein A8 |
increases expression |
EXP |
Corn Oil results in increased expression of S100A8 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 2:178,464,095...178,465,223
Ensembl chr 2:176,167,124...176,167,643
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G |
S100a9 |
S100 calcium binding protein A9 |
increases expression |
EXP |
Corn Oil results in increased expression of S100A9 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 2:178,487,941...178,490,622
Ensembl chr 2:176,190,361...176,193,230
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G |
Scd |
stearoyl-CoA desaturase |
affects expression |
EXP |
Corn Oil affects the expression of SCD1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:243,269,747...243,282,562
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G |
Scn1b |
sodium voltage-gated channel beta subunit 1 |
affects expression |
EXP |
Corn Oil affects the expression of SCN1B mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:95,481,298...95,491,211
Ensembl chr 1:86,353,917...86,363,739
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G |
Sds |
serine dehydratase |
affects expression |
EXP |
Corn Oil affects the expression of SDS mRNA |
CTD |
PMID:16360708 |
|
NCBI chr12:41,743,796...41,751,108
Ensembl chr12:36,083,229...36,088,203
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G |
Sfrp2 |
secreted frizzled-related protein 2 |
decreases expression |
EXP |
Corn Oil results in decreased expression of SFRP2 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 2:171,387,536...171,395,081
Ensembl chr 2:169,089,517...169,097,063
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G |
Slc25a20 |
solute carrier family 25 member 20 |
multiple interactions |
ISO |
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of SLC25A20 mRNA |
CTD |
PMID:36432690 |
|
NCBI chr 8:118,243,573...118,265,027
Ensembl chr 8:109,365,002...109,386,512
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G |
Slc25a25 |
solute carrier family 25 member 25 |
affects expression |
EXP |
Corn Oil affects the expression of SLC25A25 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 3:36,106,448...36,139,812
Ensembl chr 3:15,708,703...15,742,216
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G |
Sod1 |
superoxide dismutase 1 |
decreases activity multiple interactions |
ISO |
Corn Oil results in decreased activity of SOD1 protein [Corn Oil co-treated with Iron, Dietary] results in decreased activity of SOD1 protein; [Corn Oil co-treated with Iron] results in decreased activity of SOD1 protein; Iron promotes the reaction [Corn Oil results in decreased activity of SOD1 protein]; Iron, Dietary promotes the reaction [Corn Oil results in decreased activity of SOD1 protein] |
CTD |
PMID:17194920 |
|
NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249
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G |
Sparc |
secreted protein acidic and cysteine rich |
increases expression |
EXP |
Corn Oil results in increased expression of SPARC mRNA |
CTD |
PMID:22760963 |
|
NCBI chr10:40,017,065...40,038,816
Ensembl chr10:39,516,406...39,538,396
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G |
Sqle |
squalene epoxidase |
affects expression |
EXP |
Corn Oil affects the expression of SQLE mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 7:92,758,175...92,773,049
Ensembl chr 7:90,868,011...90,883,618
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
affects expression |
EXP |
Corn Oil affects the expression of SREBF1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,007,637...45,029,650
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G |
Sstr3 |
somatostatin receptor 3 |
decreases expression |
EXP |
Corn Oil results in decreased expression of SSTR3 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 7:111,973,049...111,980,250
Ensembl chr 7:110,092,575...110,099,769
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G |
Sugt1 |
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone |
increases expression |
ISO |
Corn Oil results in increased expression of SUGT1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr15:61,400,478...61,441,303
Ensembl chr15:54,990,672...55,069,150
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G |
Syk |
spleen associated tyrosine kinase |
increases expression |
ISO |
Corn Oil results in increased expression of SYK mRNA |
CTD |
PMID:23409006 |
|
NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,604,619...12,661,410
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G |
Tac1 |
tachykinin, precursor 1 |
decreases expression |
EXP |
Corn Oil results in decreased expression of TAC1 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 4:36,645,344...36,653,548
Ensembl chr 4:35,679,704...35,687,178
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G |
Tat |
tyrosine aminotransferase |
affects expression |
EXP |
Corn Oil affects the expression of TAT mRNA |
CTD |
PMID:16360708 |
|
NCBI chr19:54,856,604...54,867,168
Ensembl chr19:37,947,112...37,958,031
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G |
Tbc1d14 |
TBC1 domain family, member 14 |
affects expression |
EXP |
Corn Oil affects the expression of TBC1D14 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr14:78,397,345...78,496,863
Ensembl chr14:74,172,664...74,272,183
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G |
Tgfa |
transforming growth factor alpha |
decreases expression |
EXP |
Corn Oil results in decreased expression of TGFA mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 4:120,175,549...120,258,342
Ensembl chr 4:118,618,269...118,700,894
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G |
Ticam1 |
TIR domain containing adaptor molecule 1 |
increases expression |
ISO |
Corn Oil results in increased expression of TICAM1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 9:1,189,717...1,197,730
Ensembl chr 9:1,102,366...1,123,147
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G |
Tjp2 |
tight junction protein 2 |
increases expression |
ISO |
Corn Oil results in increased expression of TJP2 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 1:231,136,218...231,264,750
Ensembl chr 1:221,709,745...221,838,295
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G |
Tjp3 |
tight junction protein 3 |
increases expression |
ISO |
Corn Oil results in increased expression of TJP3 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 7:9,078,757...9,097,003
Ensembl chr 7:8,432,811...8,446,279
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G |
Tnfrsf1a |
TNF receptor superfamily member 1A |
increases expression |
ISO |
Corn Oil results in increased expression of TNFRSF1A mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:158,150,820...158,163,591
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G |
Tollip |
toll interacting protein |
increases expression |
ISO |
Corn Oil results in increased expression of TOLLIP mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 1:206,391,120...206,413,809
Ensembl chr 1:196,950,771...196,983,625
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G |
Tpcn2 |
two pore segment channel 2 |
affects expression |
EXP |
Corn Oil affects the expression of TPCN2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:209,845,827...209,875,561
Ensembl chr 1:200,416,540...200,446,236
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G |
Tpt1 |
tumor protein, translationally-controlled 1 |
increases expression |
EXP |
Corn Oil results in increased expression of TPT1 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr15:57,562,217...57,568,968
Ensembl chr15:51,146,154...51,159,625
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G |
Vegfb |
vascular endothelial growth factor B |
decreases expression |
EXP |
Corn Oil results in decreased expression of VEGFB mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 1:213,601,570...213,607,254
Ensembl chr 1:204,172,225...204,177,944
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G |
Vnn1 |
vanin 1 |
affects expression |
EXP |
Corn Oil affects the expression of VNN1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:23,356,324...23,366,629
Ensembl chr 1:21,537,094...21,547,395
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G |
Xiap |
X-linked inhibitor of apoptosis |
decreases expression |
ISO |
Corn Oil results in decreased expression of XIAP mRNA |
CTD |
PMID:33263755 |
|
NCBI chr X:125,756,107...125,803,979
Ensembl chr X:120,897,907...120,934,700
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G |
Xpnpep2 |
X-prolyl aminopeptidase 2 |
affects expression |
EXP |
Corn Oil affects the expression of XPNPEP2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr X:132,165,696...132,194,937
Ensembl chr X:127,287,979...127,317,223
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G |
Zdhhc23 |
zinc finger DHHC-type palmitoyltransferase 23 |
affects expression |
EXP |
Corn Oil affects the expression of ZDHHC23 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr11:70,224,581...70,240,971
Ensembl chr11:56,718,826...56,734,194
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G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
methyl oleate binds to and results in increased activity of AHR protein |
CTD |
PMID:27633901 |
|
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO |
methyl oleate binds to and results in increased activity of ESR1 protein |
CTD |
PMID:27633901 |
|
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002
|
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions |
ISO |
methyl oleate binds to and results in increased activity of PPARG protein |
CTD |
PMID:27633901 |
|
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468
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|
|
G |
Cnr1 |
cannabinoid receptor 1 |
multiple interactions |
EXP |
N-oleoyldopamine binds to and results in increased activity of CNR1 protein |
CTD |
PMID:12569099 |
|
NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:48,408,574...48,435,099
|
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G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions |
ISO |
N-oleoyldopamine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] |
CTD |
PMID:27936102 |
|
NCBI chr10:80,380,458...80,397,461
Ensembl chr10:79,883,622...79,900,624
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
ISO |
N-oleoyldopamine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] |
CTD |
PMID:27936102 |
|
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847
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|
G |
Trpv1 |
transient receptor potential cation channel, subfamily V, member 1 |
multiple interactions increases activity |
ISO EXP |
3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [N-oleoyldopamine promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; [N-oleoyldopamine results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; iodoresiniferatoxin inhibits the reaction [[N-oleoyldopamine results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; iodoresiniferatoxin inhibits the reaction [N-oleoyldopamine results in increased activity of TRPV1 protein] |
CTD |
PMID:12569099 PMID:15615864 |
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NCBI chr10:58,349,936...58,375,021
Ensembl chr10:57,851,428...57,876,513
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
increases export |
ISO |
ABCB1 protein results in increased export of N-oleoylethanolamine |
CTD |
PMID:30102254 |
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NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:25,158,362...25,442,709
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
increases response to substance multiple interactions |
ISO |
PPARA results in increased susceptibility to N-oleoylethanolamine N-oleoylethanolamine binds to and results in increased activity of PPARA protein |
CTD |
PMID:17906680 |
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NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
decreases expression |
ISO |
N-oleoylethanolamine results in decreased expression of PTGS2 protein |
CTD |
PMID:17906680 |
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NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188
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G |
Cnr1 |
cannabinoid receptor 1 |
affects binding |
ISO |
ricinoleic acid analog binds to CNR1 protein |
CTD |
PMID:16406364 |
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NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:48,408,574...48,435,099
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G |
Cnr2 |
cannabinoid receptor 2 |
multiple interactions |
ISO |
ricinoleic acid analog binds to and affects the activity of CNR2 protein |
CTD |
PMID:16406364 |
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NCBI chr 5:153,408,968...153,435,092
Ensembl chr 5:148,125,604...148,151,548
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G |
Il4 |
interleukin 4 |
multiple interactions |
ISO |
ricinoleic acid inhibits the reaction [IL4 protein results in increased expression of VCAM1 protein] |
CTD |
PMID:7544037 |
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NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750
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G |
Ptgds |
prostaglandin D2 synthase |
affects binding |
ISO |
ricinoleic acid binds to PTGDS protein |
CTD |
PMID:26456343 |
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NCBI chr 3:28,680,044...28,682,978
Ensembl chr 3:8,281,899...8,284,833
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G |
Trpv1 |
transient receptor potential cation channel, subfamily V, member 1 |
multiple interactions |
ISO |
ricinoleic acid analog binds to and affects the activity of TRPV1 protein |
CTD |
PMID:16406364 |
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NCBI chr10:58,349,936...58,375,021
Ensembl chr10:57,851,428...57,876,513
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G |
Vcam1 |
vascular cell adhesion molecule 1 |
multiple interactions |
ISO |
ricinoleic acid inhibits the reaction [IL4 protein results in increased expression of VCAM1 protein] |
CTD |
PMID:7544037 |
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NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:204,038,114...204,057,958
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G |
Abcb11 |
ATP binding cassette subfamily B member 11 |
affects expression |
EXP |
Soybean Oil affects the expression of ABCB11 mRNA |
CTD |
PMID:15770074 |
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NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:54,017,127...54,112,730
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G |
Abcb1b |
ATP-binding cassette, sub-family B member 1B |
affects expression |
EXP |
Soybean Oil affects the expression of ABCB1B mRNA |
CTD |
PMID:15770074 |
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NCBI chr 4:26,197,706...26,280,156
Ensembl chr 4:25,242,798...25,325,199
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G |
Abcb4 |
ATP binding cassette subfamily B member 4 |
affects expression |
EXP |
Soybean Oil affects the expression of ABCB4 mRNA |
CTD |
PMID:15770074 |
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NCBI chr 4:26,106,895...26,164,440
Ensembl chr 4:25,151,953...25,209,202
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G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
affects expression |
EXP |
Soybean Oil affects the expression of ABCC1 mRNA |
CTD |
PMID:15770074 |
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NCBI chr10:1,022,041...1,162,431
Ensembl chr10:531,812...655,114
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G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
affects expression |
EXP |
Soybean Oil affects the expression of ABCC2 mRNA |
CTD |
PMID:15770074 |
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NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:242,664,657...242,723,238
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G |
Abcc5 |
ATP binding cassette subfamily C member 5 |
affects expression |
EXP |
Soybean Oil affects the expression of ABCC5 mRNA |
CTD |
PMID:15770074 |
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NCBI chr11:93,975,579...94,071,659
Ensembl chr11:80,473,872...80,567,253
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G |
Abcc6 |
ATP binding cassette subfamily C member 6 |
affects expression |
EXP |
Soybean Oil affects the expression of ABCC6 mRNA |
CTD |
PMID:15770074 |
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NCBI chr 1:105,583,681...105,637,895
Ensembl chr 1:96,447,251...96,501,464
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G |
Acat1 |
acetyl-CoA acetyltransferase 1 |
decreases activity |
EXP |
Soybean Oil results in decreased activity of ACAT1 protein |
CTD |
PMID:12559476 |
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NCBI chr 8:62,876,003...62,905,080
Ensembl chr 8:53,979,813...54,008,855
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G |
Bcl2 |
BCL2, apoptosis regulator |
increases expression |
EXP |
Soybean Oil results in increased expression of BCL2 protein |
CTD |
PMID:15309441 |
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NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Cat |
catalase |
increases activity |
EXP |
Soybean Oil results in increased activity of CAT protein |
CTD |
PMID:12781854 |
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NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
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G |
Ccnd1 |
cyclin D1 |
increases expression |
EXP |
Soybean Oil results in increased expression of CCND1 mRNA |
CTD |
PMID:21088903 |
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NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602
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G |
Cyp4a1 |
cytochrome P450, family 4, subfamily a, polypeptide 1 |
affects expression |
EXP |
Soybean Oil affects the expression of CYP4A1 mRNA |
CTD |
PMID:16079505 |
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NCBI chr 5:134,360,096...134,374,233
Ensembl chr 5:129,123,336...129,137,464
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G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
increases activity |
EXP |
Soybean Oil results in increased activity of CYP7A1 protein |
CTD |
PMID:12559476 |
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NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:19,376,974...19,386,688
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G |
Gstp1 |
glutathione S-transferase pi 1 |
multiple interactions |
EXP |
Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 mRNA]; Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 protein] |
CTD |
PMID:11600134 |
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NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
increases activity |
EXP |
Soybean Oil results in increased activity of HMGCR protein |
CTD |
PMID:12559476 |
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NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:27,997,525...28,019,703
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G |
Il12b |
interleukin 12B |
decreases expression |
ISO |
Soybean Oil results in decreased expression of IL12B mRNA |
CTD |
PMID:10065739 |
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NCBI chr10:29,390,300...29,405,194
Ensembl chr10:28,893,008...28,902,903
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G |
Slc22a1 |
solute carrier family 22 member 1 |
affects expression |
EXP |
Soybean Oil affects the expression of SLC22A1 mRNA |
CTD |
PMID:15770074 |
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NCBI chr 1:50,624,339...50,651,437
Ensembl chr 1:48,076,666...48,103,678
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G |
Slc22a7 |
solute carrier family 22 member 7 |
affects expression |
EXP |
Soybean Oil affects the expression of SLC22A7 mRNA |
CTD |
PMID:15770074 |
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NCBI chr 9:22,044,672...22,052,051
Ensembl chr 9:14,547,849...14,553,921
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G |
Abca1 |
ATP binding cassette subfamily A member 1 |
decreases expression |
ISO |
Triolein results in decreased expression of ABCA1 mRNA |
CTD |
PMID:18356535 |
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NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:67,681,297...67,801,170
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G |
Abcg5 |
ATP binding cassette subfamily G member 5 |
decreases expression |
ISO |
Triolein results in decreased expression of ABCG5 mRNA |
CTD |
PMID:18356535 |
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NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:9,965,118...9,990,563
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G |
Abcg8 |
ATP binding cassette subfamily G member 8 |
decreases expression |
ISO |
Triolein results in decreased expression of ABCG8 mRNA |
CTD |
PMID:18356535 |
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NCBI chr 6:15,698,448...15,717,730
Ensembl chr 6:9,945,629...9,964,912
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G |
Acaca |
acetyl-CoA carboxylase alpha |
multiple interactions |
ISO |
Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of ACACA mRNA]]; Triolein promotes the reaction [Fructose results in increased expression of ACACA mRNA] |
CTD |
PMID:15066988 |
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NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,014,170...69,276,457
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G |
Apoa4 |
apolipoprotein A4 |
multiple interactions |
EXP |
[Taurocholic Acid co-treated with Triolein co-treated with Lecithins] results in increased expression of APOA4 protein |
CTD |
PMID:6631239 |
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NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:46,539,082...46,541,469
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G |
Apoe |
apolipoprotein E |
multiple interactions |
EXP |
[Taurocholic Acid co-treated with Triolein co-treated with Lecithins] results in decreased expression of APOE protein |
CTD |
PMID:6631239 |
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NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:79,353,916...79,357,932
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G |
App |
amyloid beta precursor protein |
multiple interactions |
EXP |
Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in increased expression of APP protein alternative form]; Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in increased expression of APP protein] |
CTD |
PMID:28734741 |
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NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561
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G |
Cat |
catalase |
multiple interactions |
EXP |
Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in decreased expression of CAT mRNA] |
CTD |
PMID:28734741 |
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NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
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G |
Cyp27a1 |
cytochrome P450, family 27, subfamily a, polypeptide 1 |
decreases expression |
ISO |
Triolein results in decreased expression of CYP27A1 mRNA |
CTD |
PMID:18356535 |
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NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:76,264,860...76,294,551
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G |
Fasn |
fatty acid synthase |
multiple interactions |
ISO |
Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of FASN mRNA]]; Triolein promotes the reaction [Fructose results in increased expression of FASN mRNA] |
CTD |
PMID:15066988 |
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NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261
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G |
Gpx1 |
glutathione peroxidase 1 |
multiple interactions |
EXP |
Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in decreased expression of GPX1 mRNA] |
CTD |
PMID:28734741 |
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NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
increases expression |
ISO |
Triolein results in increased expression of HMGCR mRNA |
CTD |
PMID:18356535 |
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NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:27,997,525...28,019,703
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G |
Mttp |
microsomal triglyceride transfer protein |
increases expression |
ISO |
Triolein results in increased expression of MTTP mRNA |
CTD |
PMID:18356535 |
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NCBI chr 2:229,286,501...229,327,650
Ensembl chr 2:226,613,090...226,654,239
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G |
Npc1l1 |
NPC1 like intracellular cholesterol transporter 1 |
decreases expression |
ISO |
Triolein results in decreased expression of NPC1L1 mRNA |
CTD |
PMID:18356535 |
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NCBI chr14:85,285,387...85,305,050
Ensembl chr14:81,071,451...81,091,113
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G |
Scd |
stearoyl-CoA desaturase |
multiple interactions |
ISO |
Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased abundance of Triglycerides]]; Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of ACACA mRNA]]; Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of FASN mRNA]]; Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of SREBF1 mRNA]]; Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of SREBF1 protein]] |
CTD |
PMID:15066988 |
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NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:243,269,747...243,282,562
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G |
Sod1 |
superoxide dismutase 1 |
multiple interactions |
EXP |
Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in decreased expression of SOD1 mRNA] |
CTD |
PMID:28734741 |
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NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249
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G |
Sod2 |
superoxide dismutase 2 |
multiple interactions |
EXP |
Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in decreased expression of SOD2 mRNA] |
CTD |
PMID:28734741 |
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NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
multiple interactions |
ISO |
Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of SREBF1 mRNA]]; Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of SREBF1 protein]] |
CTD |
PMID:15066988 |
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NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,007,637...45,029,650
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