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G |
Aldh1a1 |
aldehyde dehydrogenase family 1, subfamily A1 |
increases expression |
ISO |
benzophenone results in increased expression of ALDH1A1 mRNA |
CTD |
PMID:22584684 |
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NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829
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G |
Anapc11 |
anaphase promoting complex subunit 11 |
decreases expression |
ISO |
benzophenone results in decreased expression of ANAPC11 mRNA |
CTD |
PMID:22584684 |
|
NCBI chr11:120,489,247...120,499,024
Ensembl chr11:120,489,247...120,499,024
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G |
Ar |
androgen receptor |
affects binding |
ISO |
benzophenone binds to AR protein |
CTD |
PMID:14565775 |
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NCBI chr X:97,192,363...97,366,824
Ensembl chr X:97,192,375...97,366,821
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G |
Ccnb1 |
cyclin B1 |
increases expression |
ISO |
benzophenone results in increased expression of CCNB1 mRNA |
CTD |
PMID:22584684 |
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NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078
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G |
Cdk1 |
cyclin dependent kinase 1 |
increases expression |
ISO |
benzophenone results in increased expression of CDK1 mRNA |
CTD |
PMID:22584684 |
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NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768
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G |
Cyp2b13 |
cytochrome P450, family 2, subfamily b, polypeptide 13 |
increases expression |
ISO |
benzophenone results in increased expression of CYP2B2 mRNA |
CTD |
PMID:14613717 |
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NCBI chr 7:25,760,813...25,795,622
Ensembl chr 7:25,760,922...25,795,622
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G |
Cyp2c52-ps |
cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene |
increases expression |
ISO |
benzophenone results in increased expression of CYP2C11 mRNA |
CTD |
PMID:14613717 |
|
NCBI chr19:38,965,106...38,992,071
Ensembl chr19:38,965,091...38,991,733
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G |
Esr1 |
estrogen receptor 1 (alpha) |
multiple interactions |
ISO |
benzophenone binds to and results in increased activity of ESR1 protein |
CTD |
PMID:16079615 PMID:27633901 |
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NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
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G |
Esr2 |
estrogen receptor 2 (beta) |
multiple interactions affects binding |
ISO |
benzophenone binds to and results in increased activity of ESR2 protein benzophenone binds to ESR2 protein |
CTD |
PMID:12224631 PMID:16079615 PMID:27633901 |
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NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
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G |
Fos |
FBJ osteosarcoma oncogene |
increases expression |
ISO |
benzophenone results in increased expression of FOS mRNA; benzophenone results in increased expression of FOS protein |
CTD |
PMID:24308608 |
|
NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
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G |
Hsd3b1 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
decreases activity |
ISO |
benzophenone results in decreased activity of HSD3B1 protein |
CTD |
PMID:37217011 |
|
NCBI chr 3:98,749,672...98,767,110
Ensembl chr 3:98,759,510...98,767,110
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G |
Mir200a |
microRNA 200a |
increases expression |
ISO |
benzophenone results in increased expression of MIR200A mRNA |
CTD |
PMID:22584684 |
|
NCBI chr 4:156,139,353...156,139,442
Ensembl chr 4:156,139,353...156,139,442
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G |
Mir200b |
microRNA 200b |
increases expression |
ISO |
benzophenone results in increased expression of MIR200B mRNA |
CTD |
PMID:22584684 |
|
NCBI chr 4:156,140,138...156,140,207
Ensembl chr 4:156,140,138...156,140,207
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G |
Mir221 |
microRNA 221 |
decreases expression |
ISO |
benzophenone results in decreased expression of MIR221 mRNA |
CTD |
PMID:22584684 |
|
NCBI chr X:19,012,533...19,012,627
Ensembl chr X:19,012,533...19,012,627
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G |
Mir429 |
microRNA 429 |
increases expression |
ISO |
benzophenone results in increased expression of MIR429 mRNA |
CTD |
PMID:22584684 |
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NCBI chr 4:156,138,362...156,138,444
Ensembl chr 4:156,138,362...156,138,444
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G |
Mir96 |
microRNA 96 |
increases expression |
ISO |
benzophenone results in increased expression of MIR96 mRNA |
CTD |
PMID:22584684 |
|
NCBI chr 6:30,169,445...30,169,550
Ensembl chr 6:30,169,445...30,169,550
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
multiple interactions |
ISO |
benzophenone binds to and results in increased activity of NR1I2 protein |
CTD |
PMID:14613717 |
|
NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186
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G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
increases activity |
ISO |
benzophenone results in increased activity of NR1I3 protein |
CTD |
PMID:28927721 |
|
NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270
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G |
Nusap1 |
nucleolar and spindle associated protein 1 |
increases expression |
ISO |
benzophenone results in increased expression of NUSAP1 mRNA |
CTD |
PMID:22584684 |
|
NCBI chr 2:119,449,205...119,480,646
Ensembl chr 2:119,448,779...119,481,725
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G |
Smad3 |
SMAD family member 3 |
decreases phosphorylation multiple interactions |
ISO |
benzophenone results in decreased phosphorylation of SMAD3 protein fulvestrant inhibits the reaction [benzophenone results in decreased phosphorylation of SMAD3 protein] |
CTD |
PMID:24308608 |
|
NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276
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G |
Steap3 |
STEAP family member 3 |
decreases expression |
ISO |
benzophenone results in decreased expression of STEAP3 mRNA |
CTD |
PMID:22584684 |
|
NCBI chr 1:120,154,137...120,198,810
Ensembl chr 1:120,118,487...120,200,435
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G |
Stmn1 |
stathmin 1 |
increases expression |
ISO |
benzophenone results in increased expression of STMN1 mRNA |
CTD |
PMID:22584684 |
|
NCBI chr 4:134,195,631...134,201,154
Ensembl chr 4:134,195,631...134,201,154
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G |
Tpo |
thyroid peroxidase |
decreases activity |
ISO |
benzophenone results in decreased activity of TPO protein |
CTD |
PMID:21809831 |
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NCBI chr12:30,104,658...30,182,983
Ensembl chr12:30,104,658...30,182,623
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G |
Txnl4b |
thioredoxin-like 4B |
increases expression |
ISO |
benzophenone results in increased expression of TXNL4B mRNA |
CTD |
PMID:22584684 |
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NCBI chr 8:110,292,524...110,300,683
Ensembl chr 8:110,292,524...110,300,683
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|
G |
1600014C10Rik |
RIKEN cDNA 1600014C10 gene |
increases expression |
ISO |
Fenofibrate results in increased expression of C19ORF12 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 7:37,882,642...37,896,992
Ensembl chr 7:37,882,642...37,896,992
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G |
A1bg |
alpha-1-B glycoprotein |
decreases expression |
ISO |
Fenofibrate results in decreased expression of A1BG protein |
CTD |
PMID:20118634 |
|
NCBI chr15:60,789,438...60,793,119
Ensembl chr15:60,768,708...60,794,861
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G |
Aadac |
arylacetamide deacetylase |
increases expression |
ISO |
Fenofibrate results in increased expression of AADAC mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 3:59,939,209...59,947,578
Ensembl chr 3:59,933,138...59,947,581
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G |
Aars1 |
alanyl-tRNA synthetase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of AARS1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 8:111,759,781...111,784,237
Ensembl chr 8:111,759,776...111,784,296
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G |
Abca1 |
ATP-binding cassette, sub-family A member 1 |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of ABCA1 mRNA; Fenofibrate results in increased expression of ABCA1 protein |
CTD |
PMID:19201410 |
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NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895
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G |
Abcb11 |
ATP-binding cassette, sub-family B member 11 |
multiple interactions decreases expression decreases activity |
ISO |
Fenofibrate inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid] Fenofibrate results in decreased expression of ABCB11 mRNA Fenofibrate results in decreased activity of ABCB11 protein |
CTD |
PMID:20829430 PMID:23956101 PMID:24014644 PMID:27765674 |
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NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958
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G |
Abcb1a |
ATP-binding cassette, sub-family B member 1A |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [ABCB1 protein results in increased transport of Vincristine] |
CTD |
PMID:16316932 |
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NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
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G |
Abcb4 |
ATP-binding cassette, sub-family B member 4 |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of ABCB4 mRNA |
CTD |
PMID:17118139 PMID:19118567 |
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NCBI chr 5:8,943,614...9,009,226
Ensembl chr 5:8,943,717...9,009,231
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G |
Abcb6 |
ATP-binding cassette, sub-family B member 6 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ABCB6 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:75,148,284...75,157,066
Ensembl chr 1:75,148,361...75,157,036
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G |
Abcb9 |
ATP-binding cassette, sub-family B member 9 |
increases expression |
ISO |
Fenofibrate results in increased expression of ABCB9 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 5:124,199,920...124,234,009
Ensembl chr 5:124,199,593...124,233,861
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G |
Abcc2 |
ATP-binding cassette, sub-family member 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of ABCC2 mRNA |
CTD |
PMID:27765674 |
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NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
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G |
Abcc3 |
ATP-binding cassette, sub-family C member 3 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ABCC3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823
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G |
Abcc4 |
ATP-binding cassette, sub-family C member 4 |
increases expression |
ISO |
Fenofibrate results in increased expression of ABCC4 mRNA |
CTD |
PMID:27765674 |
|
NCBI chr14:118,720,104...118,945,475
Ensembl chr14:118,720,104...118,943,631
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G |
Abcd3 |
ATP-binding cassette, sub-family D member 3 |
increases expression |
EXP |
Fenofibrate results in increased expression of ABCD3 mRNA |
CTD |
PMID:17118139 |
|
NCBI chr 3:121,552,553...121,609,851
Ensembl chr 3:121,552,423...121,608,951
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G |
Abcg1 |
ATP binding cassette subfamily G member 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of ABCG1 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr17:31,276,668...31,336,958
Ensembl chr17:31,276,649...31,336,962
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G |
Abcg5 |
ATP binding cassette subfamily G member 5 |
increases expression |
ISO |
Fenofibrate results in increased expression of ABCG5 mRNA |
CTD |
PMID:27765674 |
|
NCBI chr17:84,965,602...84,990,439
Ensembl chr17:84,965,662...84,990,439
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G |
Abcg8 |
ATP binding cassette subfamily G member 8 |
increases expression |
ISO |
Fenofibrate results in increased expression of ABCG8 mRNA |
CTD |
PMID:27765674 |
|
NCBI chr17:84,983,730...85,007,761
Ensembl chr17:84,983,730...85,007,761
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G |
Abhd4 |
abhydrolase domain containing 4 |
increases expression |
ISO |
Fenofibrate results in increased expression of ABHD4 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr14:54,491,586...54,506,626
Ensembl chr14:54,491,645...54,508,094
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G |
Abi3bp |
ABI family member 3 binding protein |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ABI3BP mRNA |
CTD |
PMID:25572481 |
|
NCBI chr16:56,298,179...56,510,498
Ensembl chr16:56,298,241...56,510,498
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G |
Acaa1a |
acetyl-Coenzyme A acyltransferase 1A |
increases expression multiple interactions affects expression |
EXP ISO |
Fenofibrate results in increased expression of ACAA1A mRNA Fenofibrate promotes the reaction [Pyrazinamide results in increased expression of ACAA1 mRNA]; Pyrazinamide promotes the reaction [Fenofibrate results in increased expression of ACAA1 mRNA] Fenofibrate results in increased expression of ACAA1 mRNA; Fenofibrate results in increased expression of ACAA1A mRNA Fenofibrate affects the expression of ACAA1A mRNA |
CTD |
PMID:11798191 PMID:20801182 PMID:27071702 PMID:32741897 |
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NCBI chr 9:119,170,113...119,179,361
Ensembl chr 9:119,168,742...119,179,365
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G |
Acaa1b |
acetyl-Coenzyme A acyltransferase 1B |
increases expression |
ISO |
Fenofibrate results in increased expression of ACAA1 mRNA |
CTD |
PMID:24752549 |
|
NCBI chr 9:118,977,111...118,986,149
Ensembl chr 9:118,977,091...118,986,161
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G |
Acaa2 |
acetyl-CoA acyltransferase 2 |
affects expression increases expression |
ISO |
Fenofibrate affects the expression of ACAA2 mRNA Fenofibrate results in increased expression of ACAA2 mRNA Fenofibrate results in increased expression of ACAA2 mRNA; Fenofibrate results in increased expression of ACAA2 protein |
CTD |
PMID:20118634 PMID:20801182 PMID:25572481 PMID:27665778 PMID:32741897 |
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NCBI chr18:74,912,283...74,939,278
Ensembl chr18:74,912,268...74,939,279
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G |
Acaca |
acetyl-Coenzyme A carboxylase alpha |
multiple interactions decreases expression increases expression |
EXP ISO |
NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA] Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of ACACA mRNA] Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of ACACA protein modified form]; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of ACACA protein] Fenofibrate results in decreased expression of ACACA protein |
CTD |
PMID:23063693 PMID:24752549 PMID:32730863 PMID:38216941 |
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NCBI chr11:84,020,461...84,292,477
Ensembl chr11:84,020,498...84,292,477
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G |
Acacb |
acetyl-Coenzyme A carboxylase beta |
multiple interactions increases expression |
EXP |
NR1H2 gene mutant form affects the reaction [Fenofibrate results in increased expression of ACACB mRNA]; NR1H3 gene mutant form affects the reaction [Fenofibrate results in increased expression of ACACB mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACB mRNA] |
CTD |
PMID:17118139 PMID:23063693 |
|
NCBI chr 5:114,284,748...114,388,822
Ensembl chr 5:114,284,596...114,388,822
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G |
Acadl |
acyl-Coenzyme A dehydrogenase, long-chain |
increases expression |
EXP |
Fenofibrate results in increased expression of ACADL mRNA |
CTD |
PMID:17690133 |
|
NCBI chr 1:66,869,998...66,902,468
Ensembl chr 1:66,869,998...66,902,436
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G |
Acadm |
acyl-Coenzyme A dehydrogenase, medium chain |
increases expression multiple interactions |
EXP ISO |
Fenofibrate results in increased expression of ACADM mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of ACADM mRNA] |
CTD |
PMID:11798191 PMID:17690133 PMID:19124612 PMID:24752549 PMID:25572481 PMID:33408297 More...
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NCBI chr 3:153,627,990...153,650,280
Ensembl chr 3:153,627,994...153,650,269
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G |
Acads |
acyl-Coenzyme A dehydrogenase, short chain |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [ACADS protein affects the cleavage of CASP3 protein]; Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of ACADS mRNA]; Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of and results in decreased activity of ACADS protein] |
CTD |
PMID:26989860 |
|
NCBI chr 5:115,248,358...115,257,405
Ensembl chr 5:115,248,358...115,257,405
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G |
Acadvl |
acyl-Coenzyme A dehydrogenase, very long chain |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of ACADVL mRNA |
CTD |
PMID:17118139 PMID:24752549 PMID:27665778 |
|
NCBI chr11:69,901,009...69,906,254
Ensembl chr11:69,901,009...69,906,237
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G |
Acat1 |
acetyl-Coenzyme A acetyltransferase 1 |
multiple interactions increases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of ACAT1 mRNA Fenofibrate results in increased expression of ACAT1 mRNA |
CTD |
PMID:18253720 PMID:24752549 |
|
NCBI chr 9:53,491,822...53,521,650
Ensembl chr 9:53,491,822...53,521,682
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G |
Acly |
ATP citrate lyase |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of ACLY mRNA PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACLY mRNA] |
CTD |
PMID:23063693 |
|
NCBI chr11:100,367,178...100,418,826
Ensembl chr11:100,367,179...100,418,826
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G |
Aco1 |
aconitase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of ACO1 mRNA |
CTD |
PMID:17264098 |
|
NCBI chr 4:40,143,429...40,199,011
Ensembl chr 4:40,143,081...40,198,338
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G |
Aco2 |
aconitase 2, mitochondrial |
increases expression |
ISO |
Fenofibrate results in increased expression of ACO2 mRNA |
CTD |
PMID:24752549 |
|
NCBI chr15:81,756,664...81,799,338
Ensembl chr15:81,756,510...81,799,334
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G |
Acot1 |
acyl-CoA thioesterase 1 |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of ACOT1 mRNA |
CTD |
PMID:11798191 PMID:17690133 PMID:27665778 PMID:32741897 |
|
NCBI chr12:84,056,276...84,064,444
Ensembl chr12:84,056,264...84,065,145
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G |
Acot2 |
acyl-CoA thioesterase 2 |
affects expression multiple interactions increases expression |
ISO |
Fenofibrate affects the expression of ACOT2 mRNA Fenofibrate results in increased expression of and results in increased activity of ACOT2 protein Fenofibrate results in increased expression of ACOT2 mRNA |
CTD |
PMID:16595124 PMID:20801182 PMID:27665778 PMID:32741897 |
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NCBI chr12:84,034,635...84,040,651
Ensembl chr12:84,034,635...84,040,647
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G |
Acot3 |
acyl-CoA thioesterase 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of ACOT3 mRNA |
CTD |
PMID:32741897 |
|
NCBI chr12:84,098,918...84,107,174
Ensembl chr12:84,098,918...84,107,176
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G |
Acot4 |
acyl-CoA thioesterase 4 |
increases expression |
ISO |
Fenofibrate results in increased expression of ACOT4 mRNA |
CTD |
PMID:27665778 PMID:32741897 |
|
NCBI chr12:84,084,028...84,091,497
Ensembl chr12:84,085,153...84,095,375
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G |
Acot7 |
acyl-CoA thioesterase 7 |
increases expression |
ISO |
Fenofibrate results in increased expression of ACOT7 mRNA |
CTD |
PMID:32741897 |
|
NCBI chr 4:152,258,872...152,356,312
Ensembl chr 4:152,262,591...152,356,312
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G |
Acox1 |
acyl-Coenzyme A oxidase 1, palmitoyl |
affects expression multiple interactions increases expression |
ISO EXP |
Fenofibrate affects the expression of ACOX1 mRNA [Fenofibrate co-treated with Fatty Acids, Nonesterified] results in increased expression of ACOX1 protein; [Fenofibrate co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of ACOX1 mRNA]; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of ACOX1 protein]; Fenofibrate promotes the reaction [Fatty Acids, Nonesterified results in increased expression of ACOX1 mRNA]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of ACOX1 protein] Fenofibrate results in increased expression of ACOX1 mRNA; Fenofibrate results in increased expression of ACOX1 protein Fenofibrate inhibits the reaction [Zoledronic Acid results in decreased expression of ACOX1 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 protein] [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of ACOX1 mRNA |
CTD |
PMID:16707586 PMID:17118139 PMID:17690133 PMID:18253720 PMID:18775883 PMID:19395589 PMID:20801182 PMID:22301950 PMID:23063693 PMID:24534255 PMID:24735863 PMID:24752549 PMID:24986865 PMID:25572481 PMID:28871336 PMID:30611848 PMID:32741897 More...
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NCBI chr11:116,062,714...116,089,605
Ensembl chr11:116,062,714...116,089,871
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G |
Acox2 |
acyl-Coenzyme A oxidase 2, branched chain |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of ACOX2 mRNA] |
CTD |
PMID:28871336 |
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NCBI chr14:14,210,406...14,244,262
Ensembl chr14:14,210,420...14,244,262
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G |
Acsl1 |
acyl-CoA synthetase long-chain family member 1 |
increases expression multiple interactions decreases expression affects expression |
EXP ISO |
Fenofibrate results in increased expression of ACSL1 mRNA; Fenofibrate results in increased expression of ACSL1 protein PPARA protein promotes the reaction [Fenofibrate results in increased expression of ACSL1 protein] PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACSL1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACSL1 protein] Fenofibrate results in decreased expression of ACSL1 protein Fenofibrate affects the expression of ACSL1 mRNA |
CTD |
PMID:10600944 PMID:17118139 PMID:20118634 PMID:20801182 PMID:24752549 PMID:25596134 PMID:32741897 More...
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NCBI chr 8:46,924,214...46,989,088
Ensembl chr 8:46,924,074...46,989,088
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Acsl3 |
acyl-CoA synthetase long-chain family member 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of ACSL3 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 1:78,635,600...78,685,462
Ensembl chr 1:78,635,542...78,685,460
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Acsl4 |
acyl-CoA synthetase long-chain family member 4 |
increases expression |
EXP |
Fenofibrate results in increased expression of ACSL4 mRNA |
CTD |
PMID:17118139 |
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NCBI chr X:141,100,989...141,173,792
Ensembl chr X:141,100,989...141,173,531
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Acsl5 |
acyl-CoA synthetase long-chain family member 5 |
increases expression |
EXP |
Fenofibrate results in increased expression of ACSL5 mRNA |
CTD |
PMID:17118139 |
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NCBI chr19:55,240,298...55,285,060
Ensembl chr19:55,240,370...55,286,152
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Acsl6 |
acyl-CoA synthetase long-chain family member 6 |
increases expression |
ISO |
Fenofibrate results in increased expression of ACSL6 mRNA |
CTD |
PMID:16595124 |
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NCBI chr11:54,194,580...54,255,582
Ensembl chr11:54,194,624...54,255,582
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Acss2 |
acyl-CoA synthetase short-chain family member 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ACSS2 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 2:155,359,963...155,404,663
Ensembl chr 2:155,359,868...155,427,644
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Acta2 |
actin alpha 2, smooth muscle, aorta |
multiple interactions |
EXP ISO |
Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of ACTA2 protein] Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA] |
CTD |
PMID:28871336 PMID:32613381 |
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NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
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Adam22 |
a disintegrin and metallopeptidase domain 22 |
increases expression |
ISO |
Fenofibrate results in increased expression of ADAM22 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 5:8,122,353...8,418,312
Ensembl chr 5:8,122,352...8,418,160
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Adcy1 |
adenylate cyclase 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ADCY1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr11:7,013,433...7,128,506
Ensembl chr11:7,013,489...7,128,506
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G |
Adh1 |
alcohol dehydrogenase 1 (class I) |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ADH1C mRNA |
CTD |
PMID:25572481 |
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NCBI chr 3:137,983,346...137,996,459
Ensembl chr 3:137,966,752...137,996,459
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Adh4 |
alcohol dehydrogenase 4 (class II), pi polypeptide |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ADH4 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 3:138,121,217...138,138,444
Ensembl chr 3:138,121,227...138,136,653
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Adipoq |
adiponectin, C1Q and collagen domain containing |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of ADIPOQ protein [candesartan co-treated with Fenofibrate] results in increased expression of ADIPOQ protein; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of ADIPOQ protein] |
CTD |
PMID:16443859 PMID:24735863 |
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NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
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Adipor2 |
adiponectin receptor 2 |
increases expression |
EXP |
Fenofibrate results in increased expression of ADIPOR2 mRNA |
CTD |
PMID:16306350 |
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NCBI chr 6:119,330,111...119,394,489
Ensembl chr 6:119,330,111...119,394,665
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Agrn |
agrin |
decreases expression |
ISO |
Fenofibrate results in decreased expression of AGRN mRNA |
CTD |
PMID:25596134 |
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NCBI chr 4:156,249,747...156,281,997
Ensembl chr 4:156,249,747...156,281,945
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Agt |
angiotensinogen |
multiple interactions |
EXP |
Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of EDN1 mRNA]; Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of JUN mRNA]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL1A1 mRNA]]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL3A1 mRNA]]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of VEGFA protein]] |
CTD |
PMID:31016362 |
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NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445
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Agxt2 |
alanine-glyoxylate aminotransferase 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of AGXT2 mRNA |
CTD |
PMID:25572481 |
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NCBI chr15:10,358,602...10,410,244
Ensembl chr15:10,358,618...10,410,239
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Ahr |
aryl-hydrocarbon receptor |
affects activity multiple interactions |
ISO EXP |
Fenofibrate affects the activity of AHR protein Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of EDN1 mRNA]; Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of JUN mRNA]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL1A1 mRNA]]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL3A1 mRNA]]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of VEGFA protein]] |
CTD |
PMID:25596134 PMID:31016362 |
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NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
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G |
Aifm2 |
apoptosis-inducing factor, mitochondrion-associated 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of AIFM2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr10:61,551,042...61,575,474
Ensembl chr10:61,551,042...61,575,039
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Aig1 |
androgen-induced 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of AIG1 mRNA |
CTD |
PMID:32741897 |
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NCBI chr10:13,522,798...13,744,980
Ensembl chr10:13,522,798...13,744,724
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Ak4 |
adenylate kinase 4 |
affects expression |
ISO |
Fenofibrate affects the expression of AK4 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 4:101,273,675...101,324,968
Ensembl chr 4:101,276,474...101,324,192
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G |
Akr1b10 |
aldo-keto reductase family 1, member B10 |
multiple interactions decreases activity |
ISO |
Fenofibrate inhibits the reaction [AKR1B10 protein results in increased reduction of Daunorubicin]; Fenofibrate inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde] Fenofibrate results in decreased activity of AKR1B10 protein; Fenofibrate results in decreased activity of AKR1B10 protein mutant form |
CTD |
PMID:18325492 PMID:19028477 |
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NCBI chr 6:34,361,182...34,373,884
Ensembl chr 6:34,361,153...34,373,885
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Akr1c21 |
aldo-keto reductase family 1, member C21 |
increases expression |
ISO |
Fenofibrate results in increased expression of AKR1C2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr13:4,624,074...4,636,542
Ensembl chr13:4,624,074...4,636,540
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Alb |
albumin |
multiple interactions |
ISO EXP |
dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of ICAM1 mRNA]]; dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of SELE mRNA]]; dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of VCAM1 mRNA]]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased degradation of NFKBIA protein]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of ICAM1 mRNA]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of NFKB1 protein]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of RELA protein]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of SELE mRNA]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of VCAM1 mRNA]; PRKAA1 protein affects the reaction [Fenofibrate results in decreased susceptibility to ALB protein modified form] Fenofibrate inhibits the reaction [tyloxapol results in decreased expression of ALB mRNA] |
CTD |
PMID:20580385 PMID:37076581 |
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NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
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G |
Aldh1a2 |
aldehyde dehydrogenase family 1, subfamily A2 |
increases expression |
EXP |
Fenofibrate results in increased expression of ALDH1A2 mRNA |
CTD |
PMID:17118139 |
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NCBI chr 9:71,123,071...71,203,525
Ensembl chr 9:71,123,071...71,203,525
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G |
Aldh6a1 |
aldehyde dehydrogenase family 6, subfamily A1 |
increases expression |
ISO |
Fenofibrate results in increased expression of ALDH6A1 mRNA |
CTD |
PMID:24752549 |
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NCBI chr12:84,477,491...84,497,798
Ensembl chr12:84,477,491...84,497,778
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G |
Alox12 |
arachidonate 12-lipoxygenase |
increases expression |
ISO |
Fenofibrate results in increased expression of ALOX12 mRNA |
CTD |
PMID:12759900 |
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NCBI chr11:70,132,283...70,146,206
Ensembl chr11:70,132,283...70,146,179
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G |
Alpk2 |
alpha-kinase 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of ALPK2 mRNA |
CTD |
PMID:25572481 |
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NCBI chr18:65,398,600...65,526,959
Ensembl chr18:65,398,600...65,527,137
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G |
Alpl |
alkaline phosphatase, liver/bone/kidney |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ALPL mRNA |
CTD |
PMID:25572481 |
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NCBI chr 4:137,469,042...137,523,695
Ensembl chr 4:137,469,044...137,523,695
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G |
Anapc11 |
anaphase promoting complex subunit 11 |
multiple interactions decreases expression |
EXP |
PPARA protein affects the reaction [Fenofibrate results in decreased expression of ANAPC11 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr11:120,489,247...120,499,024
Ensembl chr11:120,489,247...120,499,024
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G |
Angptl4 |
angiopoietin-like 4 |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of ANGPTL4 mRNA |
CTD |
PMID:17118139 PMID:25572481 PMID:25596134 PMID:27665778 PMID:32741897 |
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NCBI chr17:33,993,874...34,000,549
Ensembl chr17:33,992,724...34,000,804
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G |
Ankra2 |
ankyrin repeat family A member 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of ANKRA2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr13:98,399,584...98,411,262
Ensembl chr13:98,399,582...98,411,262
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Anxa3 |
annexin A3 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ANXA3 protein |
CTD |
PMID:20118634 |
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NCBI chr 5:96,941,257...96,993,825
Ensembl chr 5:96,941,198...96,993,825
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G |
Apex1 |
apurinic/apyrimidinic endonuclease 1 |
multiple interactions increases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of APEX1 mRNA Fenofibrate results in increased expression of APEX1 mRNA |
CTD |
PMID:17264098 PMID:18253720 PMID:18775883 |
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NCBI chr14:51,162,406...51,164,645
Ensembl chr14:51,162,425...51,164,596
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G |
Apoa1 |
apolipoprotein A-I |
decreases expression multiple interactions |
ISO EXP |
Fenofibrate results in decreased expression of APOA1 mRNA; Fenofibrate results in decreased expression of APOA1 protein Fenofibrate promotes the reaction [APOA1 protein results in increased secretion of Lipids]; PPARA protein inhibits the reaction [Fenofibrate results in decreased expression of APOA1 mRNA] Fenofibrate promotes the reaction [APOA1 protein results in increased secretion of Lipids]; PPARA protein affects the reaction [Fenofibrate promotes the reaction [APOA1 protein results in increased secretion of Lipids]] [Fenofibrate co-treated with Pyrazinamide] results in increased expression of APOA1 mRNA |
CTD |
PMID:7983038 PMID:19201410 PMID:19445040 PMID:27071702 |
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NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764
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G |
Apoa4 |
apolipoprotein A-IV |
decreases expression |
EXP |
Fenofibrate results in decreased expression of APOA4 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 9:46,152,142...46,154,756
Ensembl chr 9:46,151,994...46,154,757
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Apob |
apolipoprotein B |
decreases expression |
ISO |
Fenofibrate results in decreased expression of APOB protein |
CTD |
PMID:21411093 |
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NCBI chr12:8,027,629...8,066,839
Ensembl chr12:8,027,648...8,066,835
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G |
Apoc3 |
apolipoprotein C-III |
affects expression decreases expression |
ISO EXP |
Fenofibrate affects the expression of APOC3 mRNA Fenofibrate results in decreased expression of APOC3 mRNA; Fenofibrate results in decreased expression of APOC3 protein |
CTD |
PMID:8847480 PMID:10799317 PMID:20801182 PMID:24752549 |
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NCBI chr 9:46,144,348...46,146,934
Ensembl chr 9:46,144,231...46,146,934
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App |
amyloid beta precursor protein |
multiple interactions |
ISO |
Fenofibrate affects the reaction [PSEN1 protein affects the cleavage of APP protein] |
CTD |
PMID:17962197 |
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NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654
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G |
Aqp3 |
aquaporin 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of AQP3 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 4:41,092,724...41,098,183
Ensembl chr 4:41,092,722...41,098,183
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Aqp7 |
aquaporin 7 |
increases expression |
ISO |
Fenofibrate results in increased expression of AQP7 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 4:41,033,074...41,048,237
Ensembl chr 4:41,033,074...41,048,139
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Aqp9 |
aquaporin 9 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of AQP9 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 9:71,017,941...71,075,170
Ensembl chr 9:71,017,941...71,075,964
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G |
Arfgef2 |
ADP ribosylation factor guanine nucleotide exchange factor 2 |
increases expression decreases expression |
ISO |
Fenofibrate results in increased expression of ARFGEF2 mRNA Fenofibrate results in decreased expression of ARFGEF2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 2:166,647,371...166,739,972
Ensembl chr 2:166,647,508...166,739,972
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G |
Arhgef10 |
Rho guanine nucleotide exchange factor 10 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ARHGEF10 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 8:14,956,405...15,051,085
Ensembl chr 8:14,961,663...15,051,085
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G |
Arih1 |
ariadne RBR E3 ubiquitin protein ligase 1 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of ARIH1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of ARIH1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 9:59,295,837...59,395,469
Ensembl chr 9:59,295,541...59,393,901
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G |
Arl1 |
ADP-ribosylation factor-like 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ARL1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr10:88,566,720...88,579,956
Ensembl chr10:88,566,720...88,579,956
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G |
Asb6 |
ankyrin repeat and SOCS box-containing 6 |
multiple interactions increases expression |
EXP |
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of ASB6 mRNA Fenofibrate results in increased expression of ASB6 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 2:30,713,109...30,718,312
Ensembl chr 2:30,713,109...30,720,345
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G |
Asns |
asparagine synthetase |
increases expression |
ISO |
Fenofibrate results in increased expression of ASNS mRNA |
CTD |
PMID:25596134 |
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NCBI chr 6:7,675,169...7,693,209
Ensembl chr 6:7,675,169...7,693,254
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G |
Ate1 |
arginyltransferase 1 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of ATE1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of ATE1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 7:129,993,219...130,122,349
Ensembl chr 7:129,993,223...130,122,099
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G |
Atf3 |
activating transcription factor 3 |
multiple interactions increases expression |
EXP ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of ATF3 mRNA Fenofibrate results in increased expression of ATF3 mRNA |
CTD |
PMID:18978307 PMID:25596134 |
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NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236
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G |
Atf4 |
activating transcription factor 4 |
affects activity multiple interactions |
ISO |
Fenofibrate affects the activity of ATF4 protein Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of ATF4 mRNA]; Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of ATF4 protein] |
CTD |
PMID:25596134 PMID:38216941 |
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NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742
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G |
Atf6 |
activating transcription factor 6 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of ATF6 mRNA]; Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of ATF6 protein] |
CTD |
PMID:38216941 |
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NCBI chr 1:170,532,026...170,696,414
Ensembl chr 1:170,532,243...170,695,340
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G |
Atg12 |
autophagy related 12 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of ATG12 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of ATG12 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr18:46,865,484...46,874,683
Ensembl chr18:46,863,211...46,874,647
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G |
Atg7 |
autophagy related 7 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of ATG7 mRNA Fenofibrate inhibits the reaction [tyloxapol results in decreased expression of ATG7 protein]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ATG7 mRNA] |
CTD |
PMID:21318169 PMID:36905866 |
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NCBI chr 6:114,620,075...114,837,565
Ensembl chr 6:114,620,058...114,837,575
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G |
Atosa |
atos homolog A |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ATOSA mRNA |
CTD |
PMID:25596134 |
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NCBI chr 9:74,860,162...74,939,750
Ensembl chr 9:74,860,151...74,939,746
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G |
Atp2a2 |
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ATP2A2 protein |
CTD |
PMID:20118634 |
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NCBI chr 5:122,591,576...122,640,288
Ensembl chr 5:122,591,576...122,640,288
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G |
Atp2b4 |
ATPase, Ca++ transporting, plasma membrane 4 |
increases expression |
ISO |
Fenofibrate results in increased expression of ATP2B4 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 1:133,630,416...133,728,755
Ensembl chr 1:133,627,195...133,728,779
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G |
Bax |
BCL2-associated X protein |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in increased expression of BAX protein] |
CTD |
PMID:26989860 |
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NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
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G |
Bcar3 |
breast cancer anti-estrogen resistance 3 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of BCAR3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 3:122,213,406...122,323,840
Ensembl chr 3:122,087,785...122,323,840
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G |
Bcat1 |
branched chain aminotransferase 1, cytosolic |
decreases expression |
ISO |
Fenofibrate results in decreased expression of BCAT1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 6:144,939,561...145,021,883
Ensembl chr 6:144,939,561...145,021,910
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G |
Bcat2 |
branched chain aminotransferase 2, mitochondrial |
increases expression |
ISO |
Fenofibrate results in increased expression of BCAT2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 7:45,219,773...45,239,134
Ensembl chr 7:45,219,577...45,239,135
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G |
Bckdk |
branched chain ketoacid dehydrogenase kinase |
decreases activity |
ISO |
Fenofibrate results in decreased activity of BCKDK protein |
CTD |
PMID:19819289 |
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NCBI chr 7:127,503,245...127,508,836
Ensembl chr 7:127,503,254...127,509,393
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G |
Bcl2 |
B cell leukemia/lymphoma 2 |
decreases expression multiple interactions |
ISO |
Fenofibrate results in decreased expression of BCL2 mRNA Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of BCL2 protein] |
CTD |
PMID:15843896 PMID:26989860 |
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NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
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G |
Bcl2a1b |
B cell leukemia/lymphoma 2 related protein A1b |
decreases expression |
ISO |
Fenofibrate results in decreased expression of BCL2A1 mRNA |
CTD |
PMID:20520642 |
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NCBI chr 9:89,081,326...89,089,891
Ensembl chr 9:89,081,262...89,089,880
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G |
Bcl2l1 |
BCL2-like 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of BCL2L1 mRNA |
CTD |
PMID:20520642 |
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NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
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G |
Bcl3 |
B cell leukemia/lymphoma 3 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of BCL3 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 7:19,542,387...19,556,691
Ensembl chr 7:19,542,387...19,556,695
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G |
Bcr |
BCR activator of RhoGEF and GTPase |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of BCR mRNA |
CTD |
PMID:18253720 |
|
NCBI chr10:74,896,384...75,020,753
Ensembl chr10:74,896,424...75,020,753
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G |
Bdh1 |
3-hydroxybutyrate dehydrogenase, type 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of BDH1 protein |
CTD |
PMID:20118634 |
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NCBI chr16:31,241,115...31,277,719
Ensembl chr16:31,241,098...31,277,719
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G |
Becn1 |
beclin 1, autophagy related |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [tyloxapol results in decreased expression of BECN1 protein] |
CTD |
PMID:36905866 |
|
NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112
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G |
Bhlhe40 |
basic helix-loop-helix family, member e40 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of BHLHE40 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 6:108,637,590...108,643,886
Ensembl chr 6:108,637,590...108,643,886
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G |
Birc3 |
baculoviral IAP repeat-containing 3 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of BIRC3 mRNA |
CTD |
PMID:20520642 |
|
NCBI chr 9:7,848,698...7,873,199
Ensembl chr 9:7,848,700...7,873,187
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G |
Bmf |
BCL2 modifying factor |
increases expression decreases expression |
ISO |
Fenofibrate results in increased expression of BMF mRNA Fenofibrate results in decreased expression of BMF mRNA |
CTD |
PMID:25572481 PMID:25596134 |
|
NCBI chr 2:118,359,238...118,385,240
Ensembl chr 2:118,359,238...118,380,168
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G |
Bnip3 |
BCL2/adenovirus E1B interacting protein 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of BNIP3 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248
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G |
Brap |
BRCA1 associated protein |
affects expression multiple interactions |
EXP |
Fenofibrate affects the expression of BRAP mRNA PPARA protein affects the reaction [Fenofibrate affects the expression of BRAP mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr 5:121,798,626...121,825,312
Ensembl chr 5:121,798,626...121,825,319
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|
G |
Brcc3 |
BRCA1/BRCA2-containing complex, subunit 3 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of BRCC3 mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of BRCC3 mRNA |
CTD |
PMID:21318169 |
|
NCBI chr X:74,460,234...74,499,307
Ensembl chr X:74,460,234...74,497,607
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G |
Brd2 |
bromodomain containing 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of BRD2 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr17:34,330,993...34,341,581
Ensembl chr17:34,330,997...34,341,608
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G |
Btg2 |
BTG anti-proliferation factor 2 |
affects expression |
ISO |
Fenofibrate affects the expression of BTG2 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 1:134,002,603...134,006,893
Ensembl chr 1:134,002,908...134,006,858
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G |
C9 |
complement component 9 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of C9 mRNA |
CTD |
PMID:11798191 |
|
NCBI chr15:6,474,827...6,528,306
Ensembl chr15:6,474,808...6,528,232
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G |
Cacna2d3 |
calcium channel, voltage-dependent, alpha2/delta subunit 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of CACNA2D3 mRNA |
CTD |
PMID:32741897 |
|
NCBI chr14:28,626,900...29,444,732
Ensembl chr14:28,626,900...29,443,821
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G |
Calm1 |
calmodulin 1 |
affects expression |
ISO |
Fenofibrate affects the expression of CALM1 mRNA |
CTD |
PMID:20801182 |
|
NCBI chr12:100,165,694...100,176,083
Ensembl chr12:100,165,694...100,176,073
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G |
Canx |
calnexin |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of CANX mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of CANX mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr11:50,184,784...50,216,500
Ensembl chr11:50,184,788...50,216,500
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G |
Car9 |
carbonic anhydrase 9 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Oxygen deficiency results in increased expression of CA9 mRNA]; Fenofibrate inhibits the reaction [Oxygen deficiency results in increased expression of CA9 protein] |
CTD |
PMID:34520103 |
|
NCBI chr 4:43,507,026...43,513,729
Ensembl chr 4:43,506,966...43,513,729
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G |
Casp3 |
caspase 3 |
increases cleavage multiple interactions decreases expression |
ISO EXP |
Fenofibrate results in increased cleavage of CASP3 protein [Fenofibrate co-treated with Pioglitazone] inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]; Fenofibrate inhibits the reaction [ACADS protein affects the cleavage of CASP3 protein]; Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]; Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of CASP3 protein] [ESR1 protein results in increased susceptibility to Estradiol] inhibits the reaction [Fenofibrate results in decreased expression of CASP3 protein]; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased activity of CASP3 protein] Fenofibrate inhibits the reaction [Cyclophosphamide results in increased cleavage of CASP3 protein] |
CTD |
PMID:20520642 PMID:26989860 PMID:29134746 PMID:32730863 PMID:36988379 PMID:38278497 More...
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NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
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G |
Casp4 |
caspase 4, apoptosis-related cysteine peptidase |
increases expression |
ISO |
Fenofibrate results in increased expression of CASP4 mRNA |
CTD |
PMID:17264098 |
|
NCBI chr 9:5,308,816...5,336,791
Ensembl chr 9:5,308,828...5,336,783
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G |
Cat |
catalase |
multiple interactions increases expression increases activity |
ISO EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased activity of CAT protein; [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CAT mRNA Fenofibrate inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein] Fenofibrate results in increased expression of CAT mRNA Fenofibrate results in increased activity of CAT protein |
CTD |
PMID:17264098 PMID:18253720 PMID:38278497 |
|
NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
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G |
Cav1 |
caveolin 1, caveolae protein |
increases expression |
ISO |
Fenofibrate results in increased expression of CAV1 mRNA |
CTD |
PMID:15314095 |
|
NCBI chr 6:17,306,387...17,341,323
Ensembl chr 6:17,306,334...17,341,451
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G |
Cblb |
Casitas B-lineage lymphoma b |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of CBLB mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of CBLB mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr16:51,851,593...52,028,410
Ensembl chr16:51,851,588...52,028,411
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G |
Ccdc34 |
coiled-coil domain containing 34 |
increases expression |
ISO |
Fenofibrate results in increased expression of CCDC34 mRNA |
CTD |
PMID:32741897 |
|
NCBI chr 2:109,847,816...110,006,007
Ensembl chr 2:109,848,162...110,003,705
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G |
Ccdc90b |
coiled-coil domain containing 90B |
increases expression |
ISO |
Fenofibrate results in increased expression of CCDC90B mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 7:92,210,350...92,231,502
Ensembl chr 7:92,210,357...92,231,502
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G |
Ccl12 |
C-C motif chemokine ligand 12 |
increases expression |
ISO |
Fenofibrate results in increased expression of CCL13 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr11:81,992,671...81,994,225
Ensembl chr11:81,992,671...81,994,226
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions decreases expression |
ISO EXP |
Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Fenofibrate inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; Fenofibrate inhibits the reaction [Glucose results in increased expression of CCL2 protein]; Fenofibrate inhibits the reaction [Glucose results in increased secretion of CCL2 protein] Fenofibrate results in decreased expression of CCL2 mRNA; Fenofibrate results in decreased expression of CCL2 protein Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein] |
CTD |
PMID:15968640 PMID:16306350 PMID:16600694 PMID:18356826 PMID:19132243 PMID:32613381 More...
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NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Chenodeoxycholic Acid results in increased expression of CCL5 mRNA]; Fenofibrate inhibits the reaction [Chenodeoxycholic Acid results in increased expression of CCL5 protein]; Fenofibrate inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; Fenofibrate inhibits the reaction [TNF protein results in increased expression of CCL5 protein] |
CTD |
PMID:12126966 PMID:12586603 |
|
NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
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G |
Ccn1 |
cellular communication network factor 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of CCN1 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 3:145,352,726...145,355,740
Ensembl chr 3:145,352,731...145,355,736
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G |
Ccnd1 |
cyclin D1 |
decreases expression increases expression multiple interactions |
ISO EXP |
Fenofibrate results in decreased expression of CCND1 mRNA; Fenofibrate results in decreased expression of CCND1 protein Fenofibrate results in increased expression of CCND1 protein ESR1 protein inhibits the reaction [Fenofibrate results in increased expression of CCND1 protein]; Estradiol inhibits the reaction [Fenofibrate results in increased expression of CCND1 protein] Fenofibrate results in increased expression of CCND1 mRNA [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CCND1 mRNA |
CTD |
PMID:16569247 PMID:17264098 PMID:18253720 PMID:18978307 PMID:20520642 PMID:29134746 More...
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NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
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G |
Ccnf |
cyclin F |
increases expression |
ISO |
Fenofibrate results in increased expression of CCNF mRNA |
CTD |
PMID:32741897 |
|
NCBI chr17:24,441,518...24,470,333
Ensembl chr17:24,441,172...24,470,458
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G |
Ccng2 |
cyclin G2 |
decreases expression increases expression |
ISO |
Fenofibrate results in decreased expression of CCNG2 mRNA Fenofibrate results in increased expression of CCNG2 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 5:93,415,432...93,424,090
Ensembl chr 5:93,415,116...93,424,090
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G |
Ccnt1 |
cyclin T1 |
multiple interactions |
ISO |
Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein] |
CTD |
PMID:20828602 |
|
NCBI chr15:98,436,570...98,468,340
Ensembl chr15:98,436,570...98,468,804
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G |
Cd14 |
CD14 antigen |
increases expression |
ISO |
Fenofibrate results in increased expression of CD14 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851
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G |
Cd36 |
CD36 molecule |
increases expression multiple interactions |
EXP ISO |
Fenofibrate results in increased expression of CD36 mRNA Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA] |
CTD |
PMID:16707586 PMID:17118139 PMID:25572481 PMID:32613381 |
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NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799
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G |
Cd40 |
CD40 antigen |
decreases expression |
ISO |
Fenofibrate results in decreased expression of CD40 mRNA |
CTD |
PMID:20520642 |
|
NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868
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G |
Cd40lg |
CD40 ligand |
multiple interactions decreases expression |
ISO |
candesartan promotes the reaction [Fenofibrate results in decreased expression of CD40LG protein]; Fenofibrate promotes the reaction [candesartan results in decreased expression of CD40LG protein] |
CTD |
PMID:16443859 |
|
NCBI chr X:56,257,448...56,269,402
Ensembl chr X:56,257,503...56,269,402
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G |
Cdc25a |
cell division cycle 25A |
increases expression |
ISO |
Fenofibrate results in increased expression of CDC25A mRNA |
CTD |
PMID:17264098 |
|
NCBI chr 9:109,704,545...109,722,963
Ensembl chr 9:109,704,647...109,722,963
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G |
Cdk20 |
cyclin dependent kinase 20 |
increases expression |
ISO |
Fenofibrate results in increased expression of CDK20 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr13:64,580,133...64,587,536
Ensembl chr13:64,580,128...64,589,587
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G |
Cdk9 |
cyclin dependent kinase 9 |
multiple interactions |
ISO |
Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein] |
CTD |
PMID:20828602 |
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NCBI chr 2:32,595,794...32,608,098
Ensembl chr 2:32,595,796...32,603,088
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G |
Cdkn1a |
cyclin dependent kinase inhibitor 1A |
multiple interactions decreases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CDKN1A mRNA Fenofibrate results in decreased expression of CDKN1A mRNA |
CTD |
PMID:18253720 PMID:25596134 |
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NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
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G |
Cdkn1b |
cyclin dependent kinase inhibitor 1B |
multiple interactions decreases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CDKN1B mRNA Fenofibrate results in decreased expression of CDKN1B protein ESR1 protein inhibits the reaction [Fenofibrate results in decreased expression of CDKN1B protein]; Estradiol inhibits the reaction [Fenofibrate results in decreased expression of CDKN1B protein] |
CTD |
PMID:18253720 PMID:29134746 |
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NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476
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G |
Cep128 |
centrosomal protein 128 |
increases expression |
ISO |
Fenofibrate results in increased expression of CEP128 mRNA |
CTD |
PMID:32741897 |
|
NCBI chr12:90,965,264...91,351,207
Ensembl chr12:90,965,266...91,351,183
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G |
Cers5 |
ceramide synthase 5 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of CERS5 mRNA |
CTD |
PMID:25596134 |
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NCBI chr15:99,633,473...99,670,396
Ensembl chr15:99,632,762...99,670,766
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G |
Ces1d |
carboxylesterase 1D |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CES1 mRNA |
CTD |
PMID:18253720 |
|
NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466
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G |
Chek1 |
checkpoint kinase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of CHEK1 mRNA |
CTD |
PMID:17264098 |
|
NCBI chr 9:36,619,935...36,637,897
Ensembl chr 9:36,619,778...36,638,361
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G |
Chek2 |
checkpoint kinase 2 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CHEK2 mRNA |
CTD |
PMID:18253720 |
|
NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011
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G |
Chid1 |
chitinase domain containing 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of CHID1 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 7:141,073,049...141,119,818
Ensembl chr 7:141,073,049...141,119,770
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G |
Chrna2 |
cholinergic receptor nicotinic alpha 2 subunit |
increases expression |
ISO |
Fenofibrate results in increased expression of CHRNA2 mRNA |
CTD |
PMID:32741897 |
|
NCBI chr14:66,370,685...66,390,397
Ensembl chr14:66,372,488...66,390,397
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G |
Chst8 |
carbohydrate sulfotransferase 8 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CHST8 mRNA |
CTD |
PMID:18253720 |
|
NCBI chr 7:34,373,893...34,512,136
Ensembl chr 7:34,373,893...34,512,136
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G |
Cish |
cytokine inducible SH2-containing protein |
decreases expression multiple interactions |
EXP |
Fenofibrate results in decreased expression of CISH mRNA PPARA protein affects the reaction [Fenofibrate results in decreased expression of CISH mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr 9:107,173,858...107,179,983
Ensembl chr 9:107,173,225...107,179,983
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G |
Cmbl |
carboxymethylenebutenolidase homolog |
increases expression |
ISO |
Fenofibrate results in increased expression of CMBL mRNA |
CTD |
PMID:25596134 |
|
NCBI chr15:31,565,314...31,590,266
Ensembl chr15:31,565,535...31,590,265
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G |
Cnot4 |
CCR4-NOT transcription complex, subunit 4 |
multiple interactions increases expression |
EXP |
PPARA protein affects the reaction [Fenofibrate results in increased expression of CNOT4 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 6:34,999,000...35,110,646
Ensembl chr 6:34,999,000...35,110,659
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G |
Col1a1 |
collagen, type I, alpha 1 |
multiple interactions |
ISO EXP |
Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]] Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL1A1 mRNA]]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Fenofibrate inhibits the reaction [Zoledronic Acid results in increased expression of COL1A1 mRNA]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]] |
CTD |
PMID:19593819 PMID:28871336 PMID:31016362 |
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NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
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G |
Col3a1 |
collagen, type III, alpha 1 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL3A1 mRNA]]; Fenofibrate inhibits the reaction [Zoledronic Acid results in increased expression of COL3A1 mRNA] |
CTD |
PMID:28871336 PMID:31016362 |
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NCBI chr 1:45,350,698...45,388,866
Ensembl chr 1:45,350,698...45,388,866
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G |
Col4a1 |
collagen, type IV, alpha 1 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of COL4A1 mRNA] |
CTD |
PMID:28871336 |
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NCBI chr 8:11,248,423...11,362,889
Ensembl chr 8:11,248,423...11,362,826
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G |
Colq |
collagen like tail subunit of asymmetric acetylcholinesterase |
increases expression |
ISO |
Fenofibrate results in increased expression of COLQ mRNA |
CTD |
PMID:27665778 PMID:32741897 |
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NCBI chr14:31,245,039...31,299,820
Ensembl chr14:31,245,039...31,313,300
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G |
Coq7 |
demethyl-Q 7 |
increases expression |
ISO |
Fenofibrate results in increased expression of COQ7 mRNA |
CTD |
PMID:16595124 |
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NCBI chr 7:118,108,881...118,132,529
Ensembl chr 7:118,108,882...118,132,579
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G |
Cox6b2 |
cytochrome c oxidase subunit 6B2 |
increases expression |
EXP |
Fenofibrate results in increased expression of COX6B2 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 7:4,754,791...4,756,093
Ensembl chr 7:4,754,791...4,756,093
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G |
Cpt1a |
carnitine palmitoyltransferase 1a, liver |
increases expression multiple interactions |
EXP ISO |
Fenofibrate results in increased expression of CPT1A mRNA Fenofibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of CPT1A protein]; Fenofibrate promotes the reaction [Fatty Acids, Nonesterified results in increased expression of CPT1A mRNA]; Fenofibrate promotes the reaction [Oleic Acid results in increased expression of CPT1A mRNA] Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of CPT1A mRNA] |
CTD |
PMID:16595124 PMID:17070643 PMID:17118139 PMID:19124612 PMID:24534255 PMID:24735863 PMID:25572481 PMID:27665778 PMID:28871336 PMID:30611848 PMID:32613381 PMID:32741897 More...
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NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733
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Cpt1b |
carnitine palmitoyltransferase 1b, muscle |
affects expression increases expression multiple interactions |
ISO |
Fenofibrate affects the expression of CPT1B mRNA Fenofibrate results in increased expression of CPT1B mRNA Fenofibrate inhibits the reaction [Pyrazinamide results in decreased expression of CPT1B mRNA] |
CTD |
PMID:16595124 PMID:19395589 PMID:20801182 PMID:27071702 PMID:32741897 |
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NCBI chr15:89,300,608...89,310,065
Ensembl chr15:89,300,608...89,310,066
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G |
Cpt2 |
carnitine palmitoyltransferase 2 |
decreases expression multiple interactions increases expression |
ISO EXP |
Fenofibrate results in decreased expression of CPT2 protein [Oleic Acid co-treated with Fenofibrate] results in increased expression of CPT2 mRNA Fenofibrate results in increased expression of CPT2 mRNA Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of CPT2 mRNA] |
CTD |
PMID:16595124 PMID:16707586 PMID:19395589 PMID:20118634 PMID:24534255 PMID:25572481 PMID:27665778 PMID:28871336 PMID:32741897 More...
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NCBI chr 4:107,761,179...107,780,786
Ensembl chr 4:107,761,178...107,780,807
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G |
Crat |
carnitine acetyltransferase |
increases expression increases activity multiple interactions |
EXP ISO |
Fenofibrate results in increased expression of CRAT mRNA Fenofibrate results in increased activity of CRAT protein [Fenofibrate co-treated with Diethylnitrosamine] results in increased activity of CRAT protein; [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CRAT mRNA |
CTD |
PMID:11798191 PMID:17264098 PMID:18253720 PMID:27665778 PMID:32741897 |
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NCBI chr 2:30,290,483...30,305,602
Ensembl chr 2:30,290,483...30,305,825
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G |
Creb3l3 |
cAMP responsive element binding protein 3-like 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of CREB3L3 mRNA |
CTD |
PMID:25572481 PMID:32741897 |
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NCBI chr10:80,920,163...80,934,706
Ensembl chr10:80,920,158...80,934,708
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G |
Crot |
carnitine O-octanoyltransferase |
increases expression |
ISO |
Fenofibrate results in increased expression of CROT mRNA |
CTD |
PMID:32741897 |
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NCBI chr 5:9,016,033...9,047,926
Ensembl chr 5:9,016,033...9,047,324
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G |
Crp |
C-reactive protein, pentraxin-related |
multiple interactions decreases expression |
ISO |
candesartan promotes the reaction [Fenofibrate results in decreased expression of CRP protein]; Fenofibrate promotes the reaction [candesartan results in decreased expression of CRP protein] |
CTD |
PMID:16123850 PMID:16443859 |
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NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598
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G |
Csf1r |
colony stimulating factor 1 receptor |
decreases expression |
ISO |
Fenofibrate results in decreased expression of CSF1R mRNA |
CTD |
PMID:16707586 |
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NCBI chr18:61,238,644...61,264,211
Ensembl chr18:61,233,670...61,265,221
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G |
Csf2 |
colony stimulating factor 2 (granulocyte-macrophage) |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CSF2 mRNA |
CTD |
PMID:18253720 |
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NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493
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G |
Cth |
cystathionine gamma lyase |
increases expression decreases expression |
ISO |
Fenofibrate results in increased expression of CTH mRNA Fenofibrate results in decreased expression of CTH mRNA |
CTD |
PMID:25596134 |
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NCBI chr 3:157,599,885...157,630,718
Ensembl chr 3:157,599,885...157,630,714
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G |
Ctsc |
cathepsin C |
decreases expression |
ISO |
Fenofibrate results in decreased expression of CTSC mRNA |
CTD |
PMID:25596134 |
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NCBI chr 7:87,927,233...87,960,083
Ensembl chr 7:87,927,293...87,960,096
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G |
Cx3cl1 |
C-X3-C motif chemokine ligand 1 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Glucose results in increased expression of CX3CL1 mRNA]; Fenofibrate inhibits the reaction [Glucose results in increased expression of CX3CL1 protein] |
CTD |
PMID:19132243 |
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NCBI chr 8:95,498,808...95,509,055
Ensembl chr 8:95,498,637...95,509,055
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G |
Cycs |
cytochrome c, somatic |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of CYCS protein] |
CTD |
PMID:32730863 |
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NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518
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G |
Cyld |
CYLD lysine 63 deubiquitinase |
decreases expression multiple interactions |
EXP |
Fenofibrate results in decreased expression of CYLD mRNA PPARA protein affects the reaction [Fenofibrate results in decreased expression of CYLD mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 8:89,423,506...89,478,574
Ensembl chr 8:89,423,675...89,478,573
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
increases expression decreases activity |
ISO |
Fenofibrate results in increased expression of CYP1A1 mRNA Fenofibrate results in decreased activity of CYP1A1 protein |
CTD |
PMID:19118567 PMID:33814510 |
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NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
multiple interactions affects expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP1A2 mRNA Fenofibrate affects the expression of CYP1A2 mRNA |
CTD |
PMID:18253720 PMID:20801182 PMID:25596134 |
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NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
decreases activity |
ISO |
Fenofibrate results in decreased activity of CYP1B1 protein |
CTD |
PMID:33814510 |
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NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
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G |
Cyp2a4 |
cytochrome P450, family 2, subfamily a, polypeptide 4 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CYP2A3 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 7:26,006,617...26,014,513
Ensembl chr 7:26,006,594...26,014,513
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G |
Cyp2b10 |
cytochrome P450, family 2, subfamily b, polypeptide 10 |
increases expression |
EXP |
Fenofibrate results in increased expression of CYP2B10 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
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G |
Cyp2b9 |
cytochrome P450, family 2, subfamily b, polypeptide 9 |
increases expression |
EXP |
Fenofibrate results in increased expression of CYP2B9 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 7:25,872,775...25,910,086
Ensembl chr 7:25,872,836...25,910,086
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G |
Cyp2c29 |
cytochrome P450, family 2, subfamily c, polypeptide 29 |
increases expression affects expression decreases activity |
ISO |
Fenofibrate results in increased expression of CYP2C8 mRNA Fenofibrate affects the expression of CYP2C8 protein Fenofibrate results in decreased activity of CYP2C8 protein |
CTD |
PMID:15601807 PMID:25572481 PMID:29960002 |
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NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157
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G |
Cyp2c38 |
cytochrome P450, family 2, subfamily c, polypeptide 38 |
increases expression |
ISO |
Fenofibrate results in increased expression of CYP2C19 mRNA |
CTD |
PMID:25572481 |
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NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519
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G |
Cyp2c52-ps |
cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP2C mRNA |
CTD |
PMID:18253720 |
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NCBI chr19:38,965,106...38,992,071
Ensembl chr19:38,965,091...38,991,733
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G |
Cyp2d22 |
cytochrome P450, family 2, subfamily d, polypeptide 22 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP2D22 mRNA |
CTD |
PMID:18253720 |
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NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of CYP2E1 mRNA |
CTD |
PMID:19118567 |
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NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
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G |
Cyp2f2 |
cytochrome P450, family 2, subfamily f, polypeptide 2 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP2F2 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 7:26,819,380...26,833,085
Ensembl chr 7:26,819,334...26,833,085
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G |
Cyp2j9 |
cytochrome P450, family 2, subfamily j, polypeptide 9 |
affects expression |
ISO |
Fenofibrate affects the expression of CYP2J2 protein |
CTD |
PMID:29960002 |
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NCBI chr 4:96,456,661...96,480,748
Ensembl chr 4:96,456,666...96,479,815
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G |
Cyp3a13 |
cytochrome P450, family 3, subfamily a, polypeptide 13 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP3A13 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881
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G |
Cyp4a10 |
cytochrome P450, family 4, subfamily a, polypeptide 10 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of CYP4A10 mRNA NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A10 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A10 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A10 mRNA] |
CTD |
PMID:23063693 |
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NCBI chr 4:115,375,484...115,390,846
Ensembl chr 4:115,375,461...115,390,846
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G |
Cyp4a12b |
cytochrome P450, family 4, subfamily a, polypeptide 12B |
increases expression multiple interactions affects expression |
EXP ISO |
Fenofibrate results in increased expression of CYP4A12B mRNA Fenofibrate results in increased expression of CYP4A1 mRNA [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CYP4A1 mRNA Fenofibrate affects the expression of CYP4A1 mRNA |
CTD |
PMID:11798191 PMID:17264098 PMID:18775883 PMID:20801182 PMID:27665778 PMID:32741897 More...
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NCBI chr 4:115,268,821...115,296,231
Ensembl chr 4:115,268,821...115,296,231
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G |
Cyp4a14 |
cytochrome P450, family 4, subfamily a, polypeptide 14 |
multiple interactions increases expression |
EXP |
[Methionine deficiency co-treated with Choline deficiency co-treated with Fenofibrate] results in increased expression of CYP4A14 mRNA; NR0B2 protein promotes the reaction [[Methionine deficiency co-treated with Choline deficiency co-treated with Fenofibrate] results in increased expression of CYP4A14 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A14 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A14 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A14 mRNA] |
CTD |
PMID:11798191 PMID:19593819 PMID:23063693 |
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NCBI chr 4:115,343,397...115,353,355
Ensembl chr 4:115,343,397...115,353,339
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G |
Cyp4a31 |
cytochrome P450, family 4, subfamily a, polypeptide 31 |
increases expression |
ISO |
Fenofibrate results in increased expression of CYP4A22 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 4:115,420,824...115,436,212
Ensembl chr 4:115,420,846...115,436,212
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G |
Cyp4b1 |
cytochrome P450, family 4, subfamily b, polypeptide 1 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP4B1 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 4:115,481,895...115,504,918
Ensembl chr 4:115,481,922...115,504,920
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G |
Cyp4x1 |
cytochrome P450, family 4, subfamily x, polypeptide 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of CYP4X1 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 4:114,963,518...114,991,276
Ensembl chr 4:114,963,520...114,991,478
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G |
Cyp7a1 |
cytochrome P450, family 7, subfamily a, polypeptide 1 |
multiple interactions decreases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP7A1 mRNA Fenofibrate results in decreased expression of CYP7A1 mRNA |
CTD |
PMID:14685799 PMID:18253720 |
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NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633
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G |
Cyp7b1 |
cytochrome P450, family 7, subfamily b, polypeptide 1 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP7B1 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 3:18,126,108...18,298,054
Ensembl chr 3:18,126,114...18,297,502
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G |
Cyp8b1 |
cytochrome P450, family 8, subfamily b, polypeptide 1 |
multiple interactions increases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP8B1 mRNA Fenofibrate results in increased expression of CYP8B1 mRNA |
CTD |
PMID:18253720 PMID:32741897 |
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NCBI chr 9:121,743,422...121,745,371
Ensembl chr 9:121,743,422...121,745,371
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G |
Dact2 |
dishevelled-binding antagonist of beta-catenin 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of DACT2 mRNA |
CTD |
PMID:27665778 |
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NCBI chr17:14,415,492...14,424,595
Ensembl chr17:14,415,314...14,424,566
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G |
Dbi |
diazepam binding inhibitor |
increases expression |
EXP |
Fenofibrate results in increased expression of DBI mRNA |
CTD |
PMID:17118139 |
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NCBI chr 1:120,041,010...120,048,826
Ensembl chr 1:120,041,010...120,048,808
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G |
Dcun1d1 |
defective in cullin neddylation 1 domain containing 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of DCUN1D1 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 3:35,946,254...35,991,626
Ensembl chr 3:35,946,254...35,991,594
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of DDIT3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157 Ensembl chr10:127,126,643...127,132,157
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G |
Ddit4 |
DNA-damage-inducible transcript 4 |
decreases expression increases expression |
ISO |
Fenofibrate results in decreased expression of DDIT4 mRNA Fenofibrate results in increased expression of DDIT4 mRNA |
CTD |
PMID:25596134 |
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NCBI chr10:59,785,497...59,787,592
Ensembl chr10:59,785,491...59,787,656
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G |
Ddx24 |
DEAD box helicase 24 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of DDX24 mRNA |
CTD |
PMID:25596134 |
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NCBI chr12:103,374,235...103,392,106
Ensembl chr12:103,374,241...103,392,089
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G |
Decr1 |
2,4-dienoyl CoA reductase 1, mitochondrial |
increases expression affects expression |
EXP ISO |
Fenofibrate results in increased expression of DECR1 mRNA Fenofibrate results in increased expression of DECR1 mRNA; Fenofibrate results in increased expression of DECR1 protein Fenofibrate affects the expression of DECR1 mRNA |
CTD |
PMID:11798191 PMID:20118634 PMID:20801182 PMID:27665778 PMID:32741897 |
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NCBI chr 4:15,917,240...15,945,377
Ensembl chr 4:15,917,240...15,945,507
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G |
Decr2 |
2-4-dienoyl-Coenzyme A reductase 2, peroxisomal |
increases expression |
ISO |
Fenofibrate results in increased expression of DECR2 mRNA |
CTD |
PMID:27665778 |
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NCBI chr17:26,300,182...26,309,096
Ensembl chr17:26,300,182...26,309,311
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G |
Dhx37 |
DEAH-box helicase 37 |
increases expression |
ISO |
Fenofibrate results in increased expression of DHX37 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 5:125,490,811...125,511,203
Ensembl chr 5:125,490,922...125,511,185
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G |
Dmd |
dystrophin, muscular dystrophy |
decreases expression |
EXP |
Fenofibrate results in decreased expression of DMD mRNA |
CTD |
PMID:11798191 |
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NCBI chr X:81,858,244...84,248,656
Ensembl chr X:81,992,476...84,249,747
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G |
Dnaja2 |
DnaJ heat shock protein family (Hsp40) member A2 |
multiple interactions increases expression |
ISO EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of DNAJA2 mRNA Fenofibrate results in increased expression of DNAJA2 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJA2 mRNA] |
CTD |
PMID:18253720 PMID:21318169 |
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NCBI chr 8:86,264,262...86,281,990
Ensembl chr 8:86,264,262...86,281,973
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G |
Dnaja3 |
DnaJ heat shock protein family (Hsp40) member A3 |
increases expression |
EXP |
Fenofibrate results in increased expression of DNAJA3 mRNA |
CTD |
PMID:21318169 |
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NCBI chr16:4,501,934...4,525,559
Ensembl chr16:4,457,853...4,525,559
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G |
Dnajb1 |
DnaJ heat shock protein family (Hsp40) member B1 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of DNAJB1 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 8:84,334,804...84,339,282
Ensembl chr 8:84,334,822...84,339,282
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G |
Dnajb4 |
DnaJ heat shock protein family (Hsp40) member B4 |
decreases expression multiple interactions |
EXP |
Fenofibrate results in decreased expression of DNAJB4 mRNA PPARA protein affects the reaction [Fenofibrate results in decreased expression of DNAJB4 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 3:151,887,217...151,915,720
Ensembl chr 3:151,884,148...151,915,939
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G |
Dnajb6 |
DnaJ heat shock protein family (Hsp40) member B6 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of DNAJB6 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJB6 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 5:29,940,896...29,991,476
Ensembl chr 5:29,940,686...30,023,132
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G |
Dnajb9 |
DnaJ heat shock protein family (Hsp40) member B9 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of DNAJB9 mRNA |
CTD |
PMID:25596134 |
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NCBI chr12:44,252,680...44,256,851
Ensembl chr12:44,252,342...44,257,109
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G |
Dnajc14 |
DnaJ heat shock protein family (Hsp40) member C14 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of DNAJC14 mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC14 mRNA |
CTD |
PMID:21318169 |
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NCBI chr10:128,641,423...128,655,317
Ensembl chr10:128,639,931...128,655,315
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G |
Dnajc19 |
DnaJ heat shock protein family (Hsp40) member C19 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of DNAJC19 mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC19 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 3:34,111,429...34,135,503
Ensembl chr 3:34,110,169...34,135,470
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G |
Dnajc2 |
DnaJ heat shock protein family (Hsp40) member C2 |
multiple interactions increases expression |
EXP |
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC2 mRNA Fenofibrate results in increased expression of DNAJC2 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 5:21,962,279...21,990,183
Ensembl chr 5:21,962,265...21,990,249
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G |
Dnajc27 |
DnaJ heat shock protein family (Hsp40) member C27 |
decreases expression multiple interactions |
EXP |
Fenofibrate results in decreased expression of RBJ mRNA PPARA protein affects the reaction [Fenofibrate results in decreased expression of RBJ mRNA] |
CTD |
PMID:21318169 |
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NCBI chr12:4,132,569...4,174,140
Ensembl chr12:4,132,583...4,160,606
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G |
Dnajc3 |
DnaJ heat shock protein family (Hsp40) member C3 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of DNAJC3 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJC3 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr14:119,175,371...119,219,114
Ensembl chr14:119,175,388...119,219,109
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G |
Dnajc5 |
DnaJ heat shock protein family (Hsp40) member C5 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of DNAJC5 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJC5 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 2:181,162,141...181,194,679
Ensembl chr 2:181,162,278...181,196,926
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Dnajc5b |
DnaJ heat shock protein family (Hsp40) member C5 beta |
increases expression |
ISO |
Fenofibrate results in increased expression of DNAJC5B mRNA |
CTD |
PMID:25596134 |
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NCBI chr 3:19,562,755...19,665,026
Ensembl chr 3:19,562,759...19,665,026
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Dnm1l |
dynamin 1-like |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of DNM1L protein] |
CTD |
PMID:32730863 |
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NCBI chr16:16,130,092...16,176,863
Ensembl chr16:16,130,094...16,176,823
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Dnmbp |
dynamin binding protein |
decreases expression |
ISO |
Fenofibrate results in decreased expression of DNMBP mRNA |
CTD |
PMID:25596134 |
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NCBI chr19:43,835,259...43,930,930
Ensembl chr19:43,835,260...43,928,630
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Dusp5 |
dual specificity phosphatase 5 |
increases expression |
ISO |
Fenofibrate results in increased expression of DUSP5 mRNA |
CTD |
PMID:25596134 |
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NCBI chr19:53,517,576...53,530,240
Ensembl chr19:53,517,540...53,530,862
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Ech1 |
enoyl coenzyme A hydratase 1, peroxisomal |
affects expression increases expression |
ISO EXP |
Fenofibrate affects the expression of ECH1 mRNA Fenofibrate results in increased expression of ECH1 mRNA; Fenofibrate results in increased expression of ECH1 protein |
CTD |
PMID:11798191 PMID:17118139 PMID:20118634 PMID:20801182 PMID:27665778 PMID:32741897 More...
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NCBI chr 7:28,524,763...28,531,664
Ensembl chr 7:28,524,642...28,531,672
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Echs1 |
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial |
increases expression |
ISO |
Fenofibrate results in increased expression of ECHS1 mRNA |
CTD |
PMID:24752549 |
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NCBI chr 7:139,685,623...139,696,334
Ensembl chr 7:139,685,623...139,696,389
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G |
Eci1 |
enoyl-Coenzyme A delta isomerase 1 |
increases expression affects expression |
EXP ISO |
Fenofibrate results in increased expression of ECI1 mRNA Fenofibrate affects the expression of ECI1 mRNA |
CTD |
PMID:11798191 PMID:20801182 PMID:27665778 PMID:32741897 |
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NCBI chr17:24,645,657...24,658,290
Ensembl chr17:24,645,615...24,658,322
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G |
Eci2 |
enoyl-Coenzyme A delta isomerase 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of ECI2 mRNA |
CTD |
PMID:16707586 |
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NCBI chr13:35,161,731...35,211,098
Ensembl chr13:35,161,731...35,211,079
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G |
Edn1 |
endothelin 1 |
multiple interactions |
ISO EXP |
EDN1 protein promotes the reaction [Fenofibrate promotes the reaction [NFATC4 protein binds to PPARA protein]]; Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]; Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to NPPB promoter]]; Fenofibrate inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]] Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of EDN1 mRNA] |
CTD |
PMID:22198280 PMID:31016362 |
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NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
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G |
Egfr |
epidermal growth factor receptor |
decreases expression |
EXP |
Fenofibrate results in decreased expression of EGFR mRNA |
CTD |
PMID:11798191 |
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NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
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G |
Ehhadh |
enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase |
increases expression affects expression |
EXP ISO |
Fenofibrate results in increased expression of EHHADH mRNA Fenofibrate affects the expression of EHHADH mRNA |
CTD |
PMID:11798191 PMID:17118139 PMID:20801182 PMID:27665778 PMID:32741897 |
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NCBI chr16:21,580,035...21,606,589
Ensembl chr16:21,580,037...21,606,557
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G |
Eif1 |
eukaryotic translation initiation factor 1 |
decreases expression increases expression |
ISO |
Fenofibrate results in decreased expression of EIF1 mRNA Fenofibrate results in increased expression of EIF1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr11:100,210,775...100,212,925
Ensembl chr11:100,210,711...100,212,922
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G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Dietary Fats results in increased phosphorylation of EIF2AK3 protein] |
CTD |
PMID:38216941 |
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NCBI chr 6:70,821,468...70,882,225
Ensembl chr 6:70,821,499...70,882,229
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G |
Eif2s2 |
eukaryotic translation initiation factor 2 subunit 2 beta |
affects expression |
ISO |
Fenofibrate affects the expression of EIF2S2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 2:154,713,330...154,734,826
Ensembl chr 2:154,713,330...154,734,855
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G |
Eif3c |
eukaryotic translation initiation factor 3, subunit C |
increases expression |
ISO |
Fenofibrate results in increased expression of EIF3C mRNA |
CTD |
PMID:25596134 |
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NCBI chr 7:126,146,083...126,165,538
Ensembl chr 7:126,145,627...126,165,583
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Elk4 |
ELK4, member of ETS oncogene family |
increases expression |
ISO |
Fenofibrate results in increased expression of ELK4 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:131,935,129...131,954,186
Ensembl chr 1:131,935,345...131,960,350
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G |
Elovl6 |
ELOVL fatty acid elongase 6 |
multiple interactions increases expression |
ISO EXP |
[Oleic Acid co-treated with Fenofibrate] affects the expression of ELOVL6 mRNA Fenofibrate results in increased expression of ELOVL6 mRNA NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA] |
CTD |
PMID:23063693 PMID:24534255 PMID:27665778 |
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NCBI chr 3:129,326,035...129,432,144
Ensembl chr 3:129,326,004...129,432,144
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G |
Enc1 |
ectodermal-neural cortex 1 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of ENC1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of ENC1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr13:97,377,613...97,389,548
Ensembl chr13:97,377,613...97,389,542
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G |
Eno1 |
enolase 1, alpha non-neuron |
increases expression |
ISO |
Fenofibrate results in increased expression of ENO1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 4:150,321,165...150,333,336
Ensembl chr 4:150,321,178...150,333,336 Ensembl chr18:150,321,178...150,333,336
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G |
Enpp2 |
ectonucleotide pyrophosphatase/phosphodiesterase 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ENPP2 mRNA |
CTD |
PMID:25572481 |
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NCBI chr15:54,702,297...54,816,284
Ensembl chr15:54,702,297...54,816,288
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G |
Entpd7 |
ectonucleoside triphosphate diphosphohydrolase 7 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ENTPD7 mRNA |
CTD |
PMID:25596134 |
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NCBI chr19:43,678,128...43,722,292
Ensembl chr19:43,678,111...43,722,136
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G |
Ep400 |
E1A binding protein p400 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of EP400 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 5:110,812,239...110,918,583
Ensembl chr 5:110,812,239...110,918,583
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G |
Ephx2 |
epoxide hydrolase 2, cytoplasmic |
affects expression increases expression |
ISO |
Fenofibrate affects the expression of EPHX2 mRNA Fenofibrate results in increased expression of EPHX2 mRNA Fenofibrate affects the expression of EPHX2 protein |
CTD |
PMID:20801182 PMID:29960002 PMID:32741897 |
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NCBI chr14:66,321,821...66,361,971
Ensembl chr14:66,321,823...66,361,949
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G |
Eprs1 |
glutamyl-prolyl-tRNA synthetase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of EPRS1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:185,093,614...185,160,557
Ensembl chr 1:185,095,241...185,160,557
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G |
Ero1a |
endoplasmic reticulum oxidoreductase 1 alpha |
increases expression |
ISO |
Fenofibrate results in increased expression of ERO1A mRNA |
CTD |
PMID:25596134 |
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NCBI chr14:45,520,544...45,556,029
Ensembl chr14:45,520,544...45,556,228
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G |
Esr1 |
estrogen receptor 1 (alpha) |
multiple interactions |
ISO |
[ESR1 protein results in increased susceptibility to Estradiol] inhibits the reaction [Fenofibrate results in decreased expression of CASP3 protein]; ESR1 protein inhibits the reaction [Estradiol inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]]; ESR1 protein inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]; ESR1 protein inhibits the reaction [Fenofibrate results in decreased expression of CDKN1B protein]; ESR1 protein inhibits the reaction [Fenofibrate results in increased expression of CCND1 protein]; ESR1 protein inhibits the reaction [Fenofibrate results in increased expression of PCNA protein]; Estradiol inhibits the reaction [ESR1 protein inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]]; Estradiol inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]; Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein] |
CTD |
PMID:29134746 |
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NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
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G |
Etfa |
electron transferring flavoprotein, alpha polypeptide |
increases expression |
ISO |
Fenofibrate results in increased expression of ETFA mRNA |
CTD |
PMID:25572481 |
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NCBI chr 9:55,361,720...55,419,528
Ensembl chr 9:55,361,792...55,419,527
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G |
Etfdh |
electron transferring flavoprotein, dehydrogenase |
decreases expression increases expression |
ISO |
Fenofibrate results in decreased expression of ETFDH protein Fenofibrate results in increased expression of ETFDH mRNA |
CTD |
PMID:20118634 PMID:25572481 |
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NCBI chr 3:79,511,095...79,536,074
Ensembl chr 3:79,511,095...79,536,807
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G |
Etnk2 |
ethanolamine kinase 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ETNK2 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 1:133,291,308...133,308,056
Ensembl chr 1:133,291,310...133,308,074
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G |
F2 |
coagulation factor II |
multiple interactions |
ISO |
Fenofibrate promotes the reaction [Warfarin results in decreased expression of F2 protein] |
CTD |
PMID:9681093 |
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NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759
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G |
F7 |
coagulation factor VII |
multiple interactions |
ISO |
Fenofibrate promotes the reaction [Warfarin results in decreased expression of F7 protein] |
CTD |
PMID:9681093 |
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NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809
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G |
Fabp1 |
fatty acid binding protein 1, liver |
increases expression multiple interactions |
EXP ISO |
Fenofibrate results in increased expression of FABP1 mRNA Fenofibrate inhibits the reaction [Pyrazinamide results in decreased expression of FABP1 mRNA] |
CTD |
PMID:17118139 PMID:24752549 PMID:27071702 PMID:32741897 |
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NCBI chr 6:71,176,863...71,182,018
Ensembl chr 6:71,176,811...71,182,007
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G |
Fabp2 |
fatty acid binding protein 2, intestinal |
increases expression |
EXP |
Fenofibrate results in increased expression of FABP2 mRNA |
CTD |
PMID:17118139 |
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NCBI chr 3:122,688,721...122,693,155
Ensembl chr 3:122,688,721...122,693,155
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G |
Fabp3 |
fatty acid binding protein 3, muscle and heart |
increases expression |
ISO |
Fenofibrate results in increased expression of FABP3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 4:130,202,531...130,209,256
Ensembl chr 4:130,202,388...130,209,256
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G |
Fabp4 |
fatty acid binding protein 4, adipocyte |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of FABP4 mRNA |
CTD |
PMID:11798191 PMID:12759900 PMID:25572481 |
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NCBI chr 3:10,269,406...10,273,653
Ensembl chr 3:10,269,148...10,273,636
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G |
Fads1 |
fatty acid desaturase 1 |
multiple interactions increases expression |
ISO |
beta-hydroxy simvastatin acid promotes the reaction [Fenofibrate results in increased expression of FADS1 mRNA]; Fenofibrate promotes the reaction [beta-hydroxy simvastatin acid results in increased expression of FADS1 mRNA] |
CTD |
PMID:17655842 |
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NCBI chr19:10,160,245...10,174,238
Ensembl chr19:10,160,252...10,174,241
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G |
Fah |
fumarylacetoacetate hydrolase |
increases expression |
ISO |
Fenofibrate results in increased expression of FAH mRNA |
CTD |
PMID:25572481 |
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NCBI chr 7:84,234,367...84,255,150
Ensembl chr 7:84,234,367...84,255,930
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G |
Fam210a |
family with sequence similarity 210, member A |
affects expression |
ISO |
Fenofibrate affects the expression of FAM210A mRNA |
CTD |
PMID:25596134 |
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NCBI chr18:68,393,248...68,433,404
Ensembl chr18:68,393,258...68,433,404
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G |
Fam222a |
family with sequence similarity 222, member A |
increases expression |
ISO |
Fenofibrate results in increased expression of FAM222A mRNA |
CTD |
PMID:25572481 |
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NCBI chr 5:114,706,312...114,751,281
Ensembl chr 5:114,706,077...114,751,281
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G |
Fam241a |
family with sequence similarity 241, member A |
increases expression |
ISO |
Fenofibrate results in increased expression of FAM241A mRNA |
CTD |
PMID:25572481 |
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NCBI chr 3:127,663,337...127,689,972
Ensembl chr 3:127,662,707...127,689,973
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G |
Fam89a |
family with sequence similarity 89, member A |
increases expression |
ISO |
Fenofibrate results in increased expression of FAM89A mRNA |
CTD |
PMID:25596134 |
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NCBI chr 8:125,466,996...125,478,605
Ensembl chr 8:125,466,996...125,478,571
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G |
Fas |
Fas cell surface death receptor |
multiple interactions decreases expression |
EXP ISO |
Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of FAS mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of FAS mRNA]] fenofibrate co-treated with fructose diet increases expression of Fas mRNA in liver Fenofibrate results in decreased expression of FAS mRNA |
CTD RGD |
PMID:19593819 PMID:25596134 PMID:11934685 |
RGD:628329 |
NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
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G |
Fasn |
fatty acid synthase |
multiple interactions increases expression |
ISO EXP |
[Oleic Acid co-treated with Fenofibrate] affects the expression of FASN mRNA; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of FASN protein] [Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in increased expression of FASN mRNA]; Fenofibrate inhibits the reaction [Fructose results in increased expression of FASN mRNA] Fenofibrate results in increased expression of FASN mRNA NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA] |
CTD |
PMID:17118139 PMID:23063693 PMID:24534255 PMID:26973390 PMID:32730863 |
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NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373
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G |
Fbp2 |
fructose bisphosphatase 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of FBP2 mRNA |
CTD |
PMID:32741897 |
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NCBI chr13:62,984,698...63,006,214
Ensembl chr13:62,984,691...63,006,236
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G |
Fbxo21 |
F-box protein 21 |
increases expression |
EXP |
Fenofibrate results in increased expression of FBXO21 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 5:118,114,835...118,148,263
Ensembl chr 5:118,114,795...118,148,266
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G |
Fbxo22 |
F-box protein 22 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of FBXO22 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 9:55,116,219...55,131,717
Ensembl chr 9:55,116,209...55,131,717
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G |
Fbxo3 |
F-box protein 3 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of FBXO3 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO3 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 2:103,858,144...103,893,582
Ensembl chr 2:103,858,066...103,893,585
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G |
Fbxo30 |
F-box protein 30 |
increases expression multiple interactions |
EXP ISO |
Fenofibrate results in increased expression of FBXO30 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO30 mRNA] |
CTD |
PMID:21318169 PMID:25596134 |
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NCBI chr10:11,157,009...11,181,494
Ensembl chr10:11,157,074...11,173,796
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G |
Fbxo32 |
F-box protein 32 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of FBXO32 mRNA; Fenofibrate results in increased expression of FBXO32 protein Lovastatin promotes the reaction [Fenofibrate results in increased expression of FBXO32 protein]; PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO32 mRNA] |
CTD |
PMID:33408297 |
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NCBI chr15:58,039,275...58,078,288
Ensembl chr15:58,039,275...58,078,328
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G |
Fbxo36 |
F-box protein 36 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of FBXO36 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 1:84,817,562...84,878,208
Ensembl chr 1:84,817,562...84,878,208
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G |
Fbxo9 |
f-box protein 9 |
increases expression |
EXP |
Fenofibrate results in increased expression of FBXO9 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 9:77,988,781...78,016,347
Ensembl chr 9:77,988,781...78,016,347
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G |
Fdft1 |
farnesyl diphosphate farnesyl transferase 1 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of FDFT1 mRNA NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FDFT1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FDFT1 mRNA] |
CTD |
PMID:23063693 |
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NCBI chr14:63,382,599...63,419,136
Ensembl chr14:63,382,599...63,417,027
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G |
Fga |
fibrinogen alpha chain |
multiple interactions decreases expression |
EXP ISO |
PPARA promotes the reaction [Fenofibrate results in decreased expression of FGA mRNA] |
CTD |
PMID:10216095 |
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NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934
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G |
Fgb |
fibrinogen beta chain |
decreases expression |
ISO |
Fenofibrate results in decreased expression of FGB mRNA |
CTD |
PMID:10216095 |
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NCBI chr 3:82,949,553...82,957,170
Ensembl chr 3:82,947,448...82,957,170
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G |
Fgf21 |
fibroblast growth factor 21 |
increases expression |
ISO |
Fenofibrate results in increased expression of FGF21 mRNA; Fenofibrate results in increased expression of FGF21 protein |
CTD |
PMID:22338096 |
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NCBI chr 7:45,263,314...45,264,914
Ensembl chr 7:45,263,310...45,264,914
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G |
Fgg |
fibrinogen gamma chain |
decreases expression |
ISO |
Fenofibrate results in decreased expression of FGG mRNA |
CTD |
PMID:10216095 |
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NCBI chr 3:82,915,031...82,922,363
Ensembl chr 3:82,915,031...82,922,356
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G |
Fgr |
FGR proto-oncogene, Src family tyrosine kinase |
affects expression |
ISO |
Fenofibrate affects the expression of FGR mRNA |
CTD |
PMID:25596134 |
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NCBI chr 4:132,701,406...132,729,204
Ensembl chr 4:132,701,406...132,729,221
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G |
Fis1 |
fission, mitochondrial 1 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of FIS1 protein] |
CTD |
PMID:32730863 |
|
NCBI chr 5:136,982,129...136,995,088
Ensembl chr 5:136,982,129...136,995,088
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G |
Fkbp15 |
FK506 binding protein 15 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of FKBP15 mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of FKBP15 mRNA |
CTD |
PMID:21318169 |
|
NCBI chr 4:62,218,579...62,278,828
Ensembl chr 4:62,218,579...62,278,785
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G |
Fkbp8 |
FK506 binding protein 8 |
increases expression |
EXP |
Fenofibrate results in increased expression of FKBP8 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 8:70,980,371...70,987,978
Ensembl chr 8:70,980,374...70,987,978
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G |
Fmo1 |
flavin containing monooxygenase 1 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of FMO1 mRNA |
CTD |
PMID:18253720 |
|
NCBI chr 1:162,657,130...162,694,170
Ensembl chr 1:162,657,130...162,694,179
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G |
Fmo5 |
flavin containing monooxygenase 5 |
multiple interactions decreases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of FMO5 mRNA Fenofibrate results in decreased expression of FMO5 mRNA |
CTD |
PMID:18253720 PMID:25572481 |
|
NCBI chr 3:97,517,248...97,562,603
Ensembl chr 3:97,536,120...97,562,598
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G |
Fn1 |
fibronectin 1 |
affects expression multiple interactions |
ISO EXP |
Fenofibrate affects the expression of FN1 mRNA Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of FN1 protein] |
CTD |
PMID:20801182 PMID:28871336 |
|
NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359
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G |
Foxo1 |
forkhead box O1 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of FOXO1 mRNA; Fenofibrate results in increased expression of FOXO1 protein Lovastatin promotes the reaction [Fenofibrate results in increased expression of FOXO1 protein]; PPARA protein affects the reaction [Fenofibrate results in increased expression of FOXO1 mRNA] |
CTD |
PMID:33408297 |
|
NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642
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G |
Foxq1 |
forkhead box Q1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of FOXQ1 mRNA |
CTD |
PMID:11798191 |
|
NCBI chr13:31,742,153...31,744,959
Ensembl chr13:31,740,117...31,744,959
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G |
G6pc1 |
glucose-6-phosphatase catalytic subunit 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of G6PC1 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr11:101,258,542...101,268,729
Ensembl chr11:101,258,387...101,268,729
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G |
Gadd45a |
growth arrest and DNA-damage-inducible 45 alpha |
multiple interactions increases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of GADD45A mRNA Fenofibrate results in increased expression of GADD45A mRNA |
CTD |
PMID:17264098 PMID:18253720 PMID:18775883 PMID:25596134 |
|
NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441
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|
G |
Gadd45b |
growth arrest and DNA-damage-inducible 45 beta |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GADD45B mRNA |
CTD |
PMID:18253720 |
|
NCBI chr10:80,765,925...80,768,038
Ensembl chr10:80,765,907...80,768,038
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G |
Galt |
galactose-1-phosphate uridyl transferase |
increases expression |
ISO |
Fenofibrate results in increased expression of GALT mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 4:41,755,517...41,759,243
Ensembl chr 4:41,755,228...41,758,695
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G |
Gars1 |
glycyl-tRNA synthetase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of GARS1 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 6:55,014,986...55,056,489
Ensembl chr 6:55,014,992...55,056,485
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G |
Gata4 |
GATA binding protein 4 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]] |
CTD |
PMID:22198280 |
|
NCBI chr14:63,436,363...63,509,161
Ensembl chr14:63,436,371...63,509,141
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G |
Gbe1 |
1,4-alpha-glucan branching enzyme 1 |
decreases expression increases expression |
ISO |
Fenofibrate results in decreased expression of GBE1 mRNA Fenofibrate results in increased expression of GBE1 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr16:70,110,837...70,366,608
Ensembl chr16:70,110,837...70,366,604
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|
G |
Gcat |
glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase) |
decreases expression |
ISO |
Fenofibrate results in decreased expression of GCAT mRNA |
CTD |
PMID:25572481 |
|
NCBI chr15:78,915,074...78,926,731
Ensembl chr15:78,915,074...78,922,553 Ensembl chr15:78,915,074...78,922,553
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
decreases expression multiple interactions |
ISO EXP |
Fenofibrate results in decreased expression of GCLC mRNA Fenofibrate inhibits the reaction [tyloxapol results in decreased expression of GCLC protein] |
CTD |
PMID:25596134 PMID:36905866 |
|
NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767
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G |
Gclm |
glutamate-cysteine ligase, modifier subunit |
increases expression |
ISO |
Fenofibrate results in increased expression of GCLM mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381
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G |
Gcnt3 |
glucosaminyl (N-acetyl) transferase 3, mucin type |
increases expression |
ISO |
Fenofibrate results in increased expression of GCNT3 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 9:69,938,777...69,947,172
Ensembl chr 9:69,938,778...69,945,370
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G |
Gde1 |
glycerophosphodiester phosphodiesterase 1 |
affects expression |
ISO |
Fenofibrate affects the expression of GDE1 mRNA |
CTD |
PMID:20801182 |
|
NCBI chr 7:118,287,781...118,304,961
Ensembl chr 7:118,287,768...118,305,001
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G |
Gdf15 |
growth differentiation factor 15 |
increases expression |
ISO |
Fenofibrate results in increased expression of GDF15 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 8:71,082,043...71,085,106
Ensembl chr 8:71,082,043...71,085,106
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G |
Gk |
glycerol kinase |
increases expression |
ISO |
Fenofibrate results in increased expression of GK mRNA |
CTD |
PMID:25572481 PMID:32741897 |
|
NCBI chr X:84,745,543...84,820,425
Ensembl chr X:84,745,543...84,820,425
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G |
Gm20348 |
predicted gene, 20348 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of TP53I3 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr12:4,860,475...4,867,155
Ensembl chr12:4,860,494...4,867,142
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G |
Gmnn |
geminin |
increases expression |
ISO |
Fenofibrate results in increased expression of GMNN mRNA |
CTD |
PMID:32741897 |
|
NCBI chr13:24,935,828...24,954,222
Ensembl chr13:24,935,828...24,945,906
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G |
Gnmt |
glycine N-methyltransferase |
decreases expression |
ISO |
Fenofibrate results in decreased expression of GNMT mRNA |
CTD |
PMID:25572481 |
|
NCBI chr17:47,036,590...47,040,091
Ensembl chr17:47,036,590...47,040,094
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G |
Got1 |
glutamic-oxaloacetic transaminase 1, soluble |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of GOT1 mRNA Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of GOT1 protein] |
CTD |
PMID:25596134 PMID:38216941 |
|
NCBI chr19:43,488,191...43,514,743
Ensembl chr19:43,488,191...43,513,044
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G |
Got2 |
glutamatic-oxaloacetic transaminase 2, mitochondrial |
increases expression |
ISO |
Fenofibrate results in increased expression of GOT2 mRNA |
CTD |
PMID:19652460 |
|
NCBI chr 8:96,590,761...96,615,029
Ensembl chr 8:96,590,762...96,615,175
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G |
Gpam |
glycerol-3-phosphate acyltransferase, mitochondrial |
increases expression |
ISO |
Fenofibrate results in increased expression of GPAM mRNA |
CTD |
PMID:16707586 |
|
NCBI chr19:55,056,067...55,115,666
Ensembl chr19:55,055,700...55,115,670
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G |
Gpat3 |
glycerol-3-phosphate acyltransferase 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of GPAT3 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 5:100,994,095...101,046,968
Ensembl chr 5:100,993,579...101,046,968
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G |
Gphn |
gephyrin |
increases expression |
ISO |
Fenofibrate results in increased expression of GPHN mRNA |
CTD |
PMID:25596134 |
|
NCBI chr12:78,264,099...78,731,546
Ensembl chr12:78,273,153...78,731,546
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G |
Gpt |
glutamic pyruvic transaminase, soluble |
multiple interactions |
ISO EXP |
Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of GPT protein]; Fenofibrate inhibits the reaction [Pyrazinamide results in increased expression of GPT protein] Fenofibrate inhibits the reaction [tyloxapol results in increased expression of GPT protein] |
CTD |
PMID:27071702 PMID:36905866 PMID:38216941 |
|
NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
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G |
Gpx1 |
glutathione peroxidase 1 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX1 mRNA] |
CTD |
PMID:31241159 |
|
NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
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G |
Gpx2 |
glutathione peroxidase 2 |
multiple interactions increases expression |
ISO EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of GPX2 mRNA Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX2 mRNA] Fenofibrate results in increased expression of GPX2 mRNA |
CTD |
PMID:17264098 PMID:18253720 PMID:18775883 PMID:31241159 |
|
NCBI chr12:76,839,109...76,842,328
Ensembl chr12:76,839,107...76,842,273
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G |
Gpx3 |
glutathione peroxidase 3 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX3 mRNA] |
CTD |
PMID:31241159 |
|
NCBI chr11:54,793,680...54,801,213
Ensembl chr11:54,793,279...54,801,203
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G |
Gpx4 |
glutathione peroxidase 4 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX4 mRNA] |
CTD |
PMID:31241159 |
|
NCBI chr10:79,883,000...79,892,273
Ensembl chr10:79,883,000...79,892,273
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G |
Grm3 |
glutamate receptor, metabotropic 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of GRM3 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 5:9,535,235...9,776,087
Ensembl chr 5:9,535,541...9,775,170
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G |
Grpel2 |
GrpE-like 2, mitochondrial |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of GRPEL2 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of GRPEL2 mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr18:61,845,495...61,860,068
Ensembl chr18:61,845,495...61,859,396
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G |
Gsr |
glutathione reductase |
increases expression |
ISO |
Fenofibrate results in increased expression of GSR mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
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G |
Gsta1 |
glutathione S-transferase, alpha 1 (Ya) |
multiple interactions increases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA Fenofibrate results in increased expression of GSTA5 mRNA |
CTD |
PMID:17264098 PMID:18253720 PMID:18775883 |
|
NCBI chr 9:78,137,951...78,149,965
Ensembl chr 9:78,137,938...78,149,966
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G |
Gsta2 |
glutathione S-transferase, alpha 2 (Yc2) |
decreases expression multiple interactions |
ISO |
Fenofibrate results in decreased expression of GSTA2 mRNA [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GSTA2 mRNA |
CTD |
PMID:18253720 PMID:18775883 |
|
NCBI chr 9:78,238,300...78,254,474
Ensembl chr 9:78,238,300...78,263,070
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G |
Gstm2 |
glutathione S-transferase, mu 2 |
multiple interactions decreases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GSTM2 mRNA Fenofibrate results in decreased expression of GSTM2 mRNA |
CTD |
PMID:18253720 PMID:18775883 |
|
NCBI chr 3:107,889,018...107,893,736
Ensembl chr 3:107,889,018...107,893,769
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G |
Gstm5 |
glutathione S-transferase, mu 5 |
multiple interactions decreases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GSTM3 mRNA Fenofibrate results in decreased expression of GSTM3 mRNA |
CTD |
PMID:18253720 PMID:18775883 |
|
NCBI chr 3:107,803,240...107,806,002
Ensembl chr 3:107,803,137...107,806,002
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G |
Gstp1 |
glutathione S-transferase, pi 1 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] |
CTD |
PMID:23769903 |
|
NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
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G |
Gstt2 |
glutathione S-transferase, theta 2 |
increases expression |
EXP |
Fenofibrate results in increased expression of GSTT2 mRNA |
CTD |
PMID:11798191 |
|
NCBI chr10:75,667,676...75,673,253
Ensembl chr10:75,666,948...75,673,258
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G |
Gtse1 |
G two S phase expressed protein 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of GTSE1 mRNA |
CTD |
PMID:32741897 |
|
NCBI chr15:85,743,928...85,760,774
Ensembl chr15:85,743,946...85,760,774
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G |
H1f2 |
H1.2 linker histone, cluster member |
decreases expression |
ISO |
Fenofibrate results in decreased expression of H1-2 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr13:23,922,790...23,923,514
Ensembl chr13:23,922,791...23,924,350
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G |
H2-Eb1 |
histocompatibility 2, class II antigen E beta |
decreases expression |
EXP |
Fenofibrate results in decreased expression of H2-EB1 mRNA |
CTD |
PMID:11798191 |
|
NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648
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G |
H2-Q1 |
histocompatibility 2, Q region locus 1 |
affects response to substance |
ISO |
HLA-A gene polymorphism affects the susceptibility to Fenofibrate |
CTD |
PMID:28043905 |
|
NCBI chr17:35,539,503...35,547,118
Ensembl chr17:35,539,381...35,544,075
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G |
Hadh |
hydroxyacyl-Coenzyme A dehydrogenase |
increases expression |
ISO |
Fenofibrate results in increased expression of HADH mRNA |
CTD |
PMID:24752549 |
|
NCBI chr 3:131,027,068...131,065,750
Ensembl chr 3:131,027,068...131,065,750
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G |
Hadha |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha |
increases expression decreases expression |
EXP ISO |
Fenofibrate results in increased expression of HADHA mRNA Fenofibrate results in decreased expression of HADHA protein |
CTD |
PMID:16707586 PMID:17118139 PMID:20118634 PMID:25572481 |
|
NCBI chr 5:30,324,421...30,359,978
Ensembl chr 5:30,323,302...30,360,160
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G |
Hadhb |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta |
increases expression decreases expression affects expression |
EXP ISO |
Fenofibrate results in increased expression of HADHB mRNA Fenofibrate results in decreased expression of HADHB protein Fenofibrate affects the expression of HADHB mRNA |
CTD |
PMID:17118139 PMID:20118634 PMID:20801182 PMID:24752549 PMID:25572481 |
|
NCBI chr 5:30,360,251...30,389,591
Ensembl chr 5:30,360,246...30,389,591
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G |
Hal |
histidine ammonia lyase |
decreases expression |
ISO |
Fenofibrate results in decreased expression of HAL mRNA |
CTD |
PMID:32741898 |
|
NCBI chr10:93,324,630...93,352,623
Ensembl chr10:93,324,630...93,355,166
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G |
Hdc |
histidine decarboxylase |
increases expression |
ISO |
Fenofibrate results in increased expression of HDC mRNA; Fenofibrate results in increased expression of HDC protein |
CTD |
PMID:32741897 PMID:32741898 |
|
NCBI chr 2:126,435,579...126,465,942
Ensembl chr 2:126,435,587...126,461,219
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G |
Hdgfl3 |
HDGF like 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of HDGFL3 mRNA |
CTD |
PMID:17264098 |
|
NCBI chr 7:81,531,004...81,587,227
Ensembl chr 7:81,530,999...81,584,221
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G |
Hectd1 |
HECT domain E3 ubiquitin protein ligase 1 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of HECTD1 mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of HECTD1 mRNA |
CTD |
PMID:21318169 |
|
NCBI chr12:51,790,504...51,876,540
Ensembl chr12:51,790,505...51,876,319
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G |
Herc3 |
hect domain and RLD 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of HERC3 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 6:58,808,440...58,897,383
Ensembl chr 6:58,808,450...58,897,383
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G |
Hes1 |
hes family bHLH transcription factor 1 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [triptolide results in increased expression of HES1 mRNA] |
CTD |
PMID:31241159 |
|
NCBI chr16:29,883,259...29,886,614
Ensembl chr16:29,883,202...29,886,614
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G |
Hif1a |
hypoxia inducible factor 1, alpha subunit |
increases expression multiple interactions affects activity |
EXP ISO |
Fenofibrate results in increased expression of HIF1A mRNA Fenofibrate inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; Fenofibrate results in decreased expression of and results in increased degradation of HIF1A protein Fenofibrate affects the activity of HIF1A protein |
CTD |
PMID:17118139 PMID:25596134 PMID:34520103 |
|
NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304
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G |
Hilpda |
hypoxia inducible lipid droplet associated |
increases expression |
ISO |
Fenofibrate results in increased expression of HILPDA mRNA |
CTD |
PMID:32741897 |
|
NCBI chr 6:29,272,487...29,275,448
Ensembl chr 6:29,272,487...29,275,445
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-Coenzyme A reductase |
increases expression decreases expression multiple interactions |
EXP ISO |
Fenofibrate results in increased expression of HMGCR mRNA Fenofibrate results in decreased expression of HMGCR mRNA NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of HMGCR mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of HMGCR mRNA] |
CTD |
PMID:16595124 PMID:23063693 |
|
NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
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G |
Hmgcs1 |
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of HMGCS1 mRNA |
CTD |
PMID:11798191 |
|
NCBI chr13:120,151,887...120,169,796
Ensembl chr13:120,151,915...120,169,796
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G |
Hmgcs2 |
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of HMGCS2 mRNA |
CTD |
PMID:25572481 PMID:27665778 PMID:32741897 |
|
NCBI chr 3:98,187,747...98,218,054
Ensembl chr 3:98,187,751...98,218,054
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G |
Hmox1 |
heme oxygenase 1 |
increases expression multiple interactions |
ISO EXP |
Fenofibrate results in increased expression of HMOX1 mRNA dorsomorphin inhibits the reaction [Fenofibrate results in increased expression of HMOX1 protein] Fenofibrate results in increased expression of HMOX1 mRNA; Fenofibrate results in increased expression of HMOX1 protein |
CTD |
PMID:25596134 PMID:34520103 |
|
NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
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|
G |
Hoga1 |
4-hydroxy-2-oxoglutarate aldolase 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of HOGA1 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr19:42,033,998...42,060,128
Ensembl chr19:42,034,049...42,059,392
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|
G |
Hras |
Harvey rat sarcoma virus oncogene |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of HRAS mRNA |
CTD |
PMID:18978307 |
|
NCBI chr 7:140,770,839...140,773,938
Ensembl chr 7:140,769,018...140,773,918
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|
G |
Hsd11b1 |
hydroxysteroid 11-beta dehydrogenase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of HSD11B1 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 1:192,903,917...192,946,345
Ensembl chr 1:192,903,942...192,946,383
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|
G |
Hsd17b4 |
hydroxysteroid (17-beta) dehydrogenase 4 |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of HSD17B4 mRNA |
CTD |
PMID:17118139 PMID:25572481 |
|
NCBI chr18:50,261,268...50,329,337
Ensembl chr18:50,261,268...50,329,336
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G |
Hsd3b5 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of HSD3B5 mRNA |
CTD |
PMID:11798191 |
|
NCBI chr 3:98,525,952...98,552,850
Ensembl chr 3:98,525,950...98,537,568
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G |
Hsdl2 |
hydroxysteroid dehydrogenase like 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of HSDL2 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 4:59,581,515...59,618,694
Ensembl chr 4:59,581,563...59,618,689
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G |
Hsf1 |
heat shock factor 1 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of HSF1 mRNA |
CTD |
PMID:18253720 |
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NCBI chr15:76,361,562...76,385,355
Ensembl chr15:76,361,622...76,386,113
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G |
Hsp90aa1 |
heat shock protein 90, alpha (cytosolic), class A member 1 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of HSP90AA1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of HSP90AA1 mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr12:110,657,470...110,662,829
Ensembl chr12:110,657,039...110,669,162
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G |
Hsp90ab1 |
heat shock protein 90 alpha (cytosolic), class B member 1 |
multiple interactions increases expression |
EXP |
PPARA protein affects the reaction [Fenofibrate results in increased expression of HSP90AB1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr17:45,878,704...45,884,187
Ensembl chr17:45,878,701...45,884,197
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G |
Hsp90b1 |
heat shock protein 90, beta (Grp94), member 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of HSP90B1 mRNA |
CTD |
PMID:21318169 |
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NCBI chr10:86,526,705...86,541,308
Ensembl chr10:86,526,073...86,541,373
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G |
Hspa13 |
heat shock protein 70 family, member 13 |
decreases expression multiple interactions |
EXP |
Fenofibrate results in decreased expression of HSPA13 mRNA PPARA protein affects the reaction [Fenofibrate results in decreased expression of HSPA13 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr16:75,552,078...75,564,575
Ensembl chr16:75,542,319...75,563,992
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G |
Hspa4l |
heat shock protein 4 like |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of HSPA4L mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA4L mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 3:40,698,664...40,750,538
Ensembl chr 3:40,699,814...40,750,538
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G |
Hspa5 |
heat shock protein 5 |
decreases expression multiple interactions |
ISO |
Fenofibrate results in decreased expression of HSPA5 mRNA Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of HSPA5 protein] |
CTD |
PMID:25596134 PMID:38216941 |
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NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
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G |
Hspa8 |
heat shock protein 8 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of HSPA8 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA8 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383
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G |
Hspa9 |
heat shock protein 9 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of HSPA9 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA9 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr18:35,070,467...35,087,404
Ensembl chr18:35,070,467...35,087,410
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G |
Hspb1 |
heat shock protein 1 |
affects expression multiple interactions increases expression |
ISO EXP |
Fenofibrate affects the expression of HSPB1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPB1 mRNA] |
CTD |
PMID:20801182 PMID:21318169 |
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NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417
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G |
Hspb8 |
heat shock protein 8 |
multiple interactions increases expression |
EXP |
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of HSPB8 mRNA Fenofibrate results in increased expression of HSPB8 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 5:116,546,550...116,560,923
Ensembl chr 5:116,546,550...116,560,923
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G |
Hspe1 |
heat shock protein 1 (chaperonin 10) |
affects expression |
ISO |
Fenofibrate affects the expression of HSPE1 mRNA |
CTD |
PMID:20801182 |
|
NCBI chr 1:55,127,307...55,130,476
Ensembl chr 1:55,127,291...55,130,466
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G |
Hsph1 |
heat shock 105kDa/110kDa protein 1 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of HSPH1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPH1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 5:149,540,308...149,562,594
Ensembl chr 5:149,537,752...149,559,841
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G |
Htatip2 |
HIV-1 Tat interactive protein 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of HTATIP2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 7:49,408,761...49,423,748
Ensembl chr 7:49,408,863...49,423,723
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G |
Iars1 |
isoleucyl-tRNA synthetase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of IARS1 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr13:49,835,606...49,887,743
Ensembl chr13:49,835,576...49,887,743
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions |
EXP ISO |
Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA] dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of ICAM1 mRNA]]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of ICAM1 mRNA] |
CTD |
PMID:20580385 PMID:21300114 |
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NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
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G |
Id2 |
inhibitor of DNA binding 2 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of ID2 mRNA |
CTD |
PMID:11798191 |
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NCBI chr12:25,143,798...25,146,091
Ensembl chr12:25,143,798...25,147,139
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G |
Idh3b |
isocitrate dehydrogenase 3 (NAD+) beta |
increases expression |
ISO |
Fenofibrate results in increased expression of IDH3B mRNA |
CTD |
PMID:24752549 |
|
NCBI chr 2:130,121,229...130,126,371
Ensembl chr 2:130,121,229...130,126,467
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G |
Iffo1 |
intermediate filament family orphan 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of IFFO1 mRNA |
CTD |
PMID:16707586 |
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NCBI chr 6:125,122,167...125,138,746
Ensembl chr 6:125,122,204...125,138,745
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G |
Ifng |
interferon gamma |
multiple interactions |
ISO |
Fenofibrate results in decreased susceptibility to [IFNG protein co-treated with IL1B protein] |
CTD |
PMID:20631892 |
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NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
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G |
Igf2r |
insulin-like growth factor 2 receptor |
decreases expression |
ISO |
Fenofibrate results in decreased expression of IGF2R mRNA |
CTD |
PMID:25596134 |
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NCBI chr17:12,901,293...12,988,593
Ensembl chr17:12,901,293...12,988,551
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G |
Il12b |
interleukin 12b |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] |
CTD |
PMID:15968640 |
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NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860
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G |
Il17rb |
interleukin 17 receptor B |
decreases expression |
ISO |
Fenofibrate results in decreased expression of IL17RB mRNA |
CTD |
PMID:25596134 |
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NCBI chr14:29,718,125...29,730,853
Ensembl chr14:29,718,092...29,730,853
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
EXP ISO |
[Fenofibrate co-treated with Alitretinoin] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Fenofibrate inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Fenofibrate inhibits the reaction [triptolide results in increased expression of IL1B mRNA] Fenofibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein] Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]; Fenofibrate promotes the reaction [Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]]; Fenofibrate results in decreased susceptibility to [IFNG protein co-treated with IL1B protein]; Pioglitazone promotes the reaction [Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]] |
CTD |
PMID:15968640 PMID:20631892 PMID:21300114 PMID:31241159 PMID:32613381 PMID:36988379 PMID:38278497 More...
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NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
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G |
Il6 |
interleukin 6 |
multiple interactions affects response to substance |
EXP ISO |
[Fenofibrate co-treated with Alitretinoin] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 mRNA]; Fenofibrate inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of IL6 mRNA]; Fenofibrate inhibits the reaction [triptolide results in increased expression of IL6 mRNA]; Fenofibrate inhibits the reaction [tyloxapol results in increased expression of IL6 mRNA]; Fenofibrate promotes the reaction [Dextran Sulfate results in increased expression of IL6 protein]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of IL6 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 mRNA]] IL6 promoter polymorphism affects the susceptibility to Fenofibrate |
CTD |
PMID:15968640 PMID:16607077 PMID:19593819 PMID:21300114 PMID:25035112 PMID:31241159 PMID:37076581 PMID:38278497 More...
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NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
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G |
Ins1 |
insulin I |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Fructose results in increased secretion of INS1 protein] |
CTD |
PMID:26973390 |
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NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914
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G |
Ins2 |
insulin II |
multiple interactions |
ISO |
Fenofibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein] |
CTD |
PMID:32613381 |
|
NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118
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G |
Insig1 |
insulin induced gene 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of INSIG1 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 5:28,276,410...28,283,660
Ensembl chr 5:28,276,361...28,283,660
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G |
Insig2 |
insulin induced gene 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of INSIG2 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 1:121,232,082...121,260,391
Ensembl chr 1:121,232,082...121,260,318
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G |
Irak2 |
interleukin-1 receptor-associated kinase 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of IRAK2 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 6:113,615,428...113,671,987
Ensembl chr 6:113,615,428...113,671,987
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G |
Irf7 |
interferon regulatory factor 7 |
increases expression |
ISO |
Fenofibrate results in increased expression of IRF7 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 7:140,843,096...140,846,412
Ensembl chr 7:140,842,619...140,846,394
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G |
Itch |
itchy, E3 ubiquitin protein ligase |
multiple interactions decreases expression |
EXP |
PPARA protein affects the reaction [Fenofibrate results in decreased expression of ITCH mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr 2:154,975,401...155,068,775
Ensembl chr 2:154,975,429...155,068,775
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G |
Itfg2 |
integrin alpha FG-GAP repeat containing 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of ITFG2 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 6:128,386,407...128,401,873
Ensembl chr 6:128,386,407...128,401,894
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G |
Itgb1 |
integrin beta 1 (fibronectin receptor beta) |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ITGB1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 8:129,412,135...129,460,060
Ensembl chr 8:129,412,135...129,459,681
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G |
Itgb3 |
integrin beta 3 |
affects expression |
ISO |
Fenofibrate affects the expression of ITGB3 mRNA |
CTD |
PMID:20801182 |
|
NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302
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G |
Jun |
jun proto-oncogene |
multiple interactions |
ISO EXP |
Fenofibrate inhibits the reaction [Glucose results in increased expression of JUN protein] [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of JUN mRNA; Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of JUN mRNA] |
CTD |
PMID:16600694 PMID:18978307 PMID:31016362 |
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NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
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G |
Kcnk13 |
potassium channel, subfamily K, member 13 |
increases expression |
ISO |
Fenofibrate results in increased expression of KCNK13 mRNA |
CTD |
PMID:25572481 PMID:25596134 |
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NCBI chr12:99,928,132...100,028,941
Ensembl chr12:99,930,758...100,028,941
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G |
Keap1 |
kelch-like ECH-associated protein 1 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [tyloxapol results in increased expression of KEAP1 protein] |
CTD |
PMID:36905866 |
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NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657
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G |
Kif22 |
kinesin family member 22 |
increases expression |
ISO |
Fenofibrate results in increased expression of KIF22 mRNA |
CTD |
PMID:32741897 |
|
NCBI chr 7:126,626,901...126,641,639
Ensembl chr 7:126,626,901...126,641,643
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G |
Kifc1 |
kinesin family member C1 |
increases expression |
ISO |
Fenofibrate results in increased expression of KIFC1 mRNA |
CTD |
PMID:32741897 |
|
NCBI chr17:34,094,640...34,109,607
Ensembl chr17:34,094,633...34,109,635
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G |
Klf10 |
Kruppel-like transcription factor 10 |
decreases expression increases expression |
EXP ISO |
Fenofibrate results in decreased expression of KLF10 mRNA Fenofibrate results in increased expression of KLF10 mRNA |
CTD |
PMID:11798191 PMID:25572481 |
|
NCBI chr15:38,291,702...38,300,950
Ensembl chr15:38,291,707...38,300,950
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G |
Klf11 |
Kruppel-like transcription factor 11 |
increases expression |
ISO |
Fenofibrate results in increased expression of KLF11 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr12:24,701,370...24,712,781
Ensembl chr12:24,701,273...24,712,788
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G |
Krt18 |
keratin 18 |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of KRT18 protein |
CTD |
PMID:18978307 |
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NCBI chr15:101,936,651...101,940,461
Ensembl chr15:101,936,615...101,940,462
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G |
Krt23 |
keratin 23 |
increases expression |
ISO |
Fenofibrate results in increased expression of KRT23 mRNA |
CTD |
PMID:32741897 |
|
NCBI chr11:99,368,799...99,383,946
Ensembl chr11:99,368,800...99,383,963
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G |
Krt8 |
keratin 8 |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of KRT8 protein |
CTD |
PMID:18978307 |
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NCBI chr15:101,905,146...101,912,777
Ensembl chr15:101,905,133...101,912,917
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G |
Krtap1-4 |
keratin associated protein 1-4 |
increases expression |
ISO |
Fenofibrate results in increased expression of KRTAP1-5 mRNA |
CTD |
PMID:32741897 |
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NCBI chr11:99,473,375...99,474,503
Ensembl chr11:99,473,888...99,474,480
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G |
Lama4 |
laminin, alpha 4 |
increases expression |
ISO |
Fenofibrate results in increased expression of LAMA4 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr10:38,841,511...38,986,184
Ensembl chr10:38,841,511...38,986,184
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G |
Lars1 |
leucyl-tRNA synthetase 1 |
increases expression decreases expression |
ISO |
Fenofibrate results in increased expression of LARS1 mRNA Fenofibrate results in decreased expression of LARS1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr18:42,335,363...42,395,302
Ensembl chr18:42,335,363...42,395,259
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G |
Lbh |
limb-bud and heart |
increases expression |
ISO |
Fenofibrate results in increased expression of LBH mRNA |
CTD |
PMID:25572481 |
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NCBI chr17:73,225,300...73,248,941
Ensembl chr17:73,225,300...73,248,942
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G |
Ldhb |
lactate dehydrogenase B |
increases expression |
ISO |
Fenofibrate results in increased expression of LDHB mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 6:142,435,975...142,453,683
Ensembl chr 6:142,435,975...142,453,683
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G |
Lep |
leptin |
multiple interactions |
ISO |
[Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in increased expression of LEP mRNA]; Fenofibrate inhibits the reaction [Fructose results in increased expression of LEP mRNA] Fenofibrate inhibits the reaction [Arsenic Trioxide results in decreased expression of and results in decreased secretion of LEP protein] |
CTD |
PMID:26973390 PMID:32929351 |
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NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
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G |
Lgals1 |
lectin, galactose binding, soluble 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of LGALS1 mRNA |
CTD |
PMID:11798191 |
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NCBI chr15:78,810,925...78,814,665
Ensembl chr15:78,810,925...78,814,665
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G |
Lifr |
LIF receptor alpha |
decreases expression |
EXP |
Fenofibrate results in decreased expression of LIFR mRNA |
CTD |
PMID:11798191 |
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NCBI chr15:7,120,091...7,226,970
Ensembl chr15:7,120,095...7,226,970
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G |
Lmcd1 |
LIM and cysteine-rich domains 1 |
affects expression |
ISO |
Fenofibrate affects the expression of LMCD1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 6:112,250,747...112,307,384
Ensembl chr 6:112,250,719...112,307,386
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G |
Lnx1 |
ligand of numb-protein X 1 |
multiple interactions decreases expression |
EXP |
PPARA protein affects the reaction [Fenofibrate results in decreased expression of LNX1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 5:74,753,108...74,865,203
Ensembl chr 5:74,753,108...74,863,573
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G |
Lpcat2 |
lysophosphatidylcholine acyltransferase 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of LPCAT2 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 8:93,581,948...93,645,907
Ensembl chr 8:93,581,967...93,645,907
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G |
Lpcat3 |
lysophosphatidylcholine acyltransferase 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of LPCAT3 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 6:124,639,887...124,681,142
Ensembl chr 6:124,639,990...124,681,381
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G |
Lpl |
lipoprotein lipase |
increases expression multiple interactions increases activity |
EXP ISO |
Fenofibrate results in increased expression of LPL mRNA; Fenofibrate results in increased expression of LPL protein PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LPL mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LPL protein] PPARA protein promotes the reaction [Fenofibrate results in increased expression of LPL protein] Fenofibrate inhibits the reaction [Pyrazinamide results in decreased expression of LPL mRNA] Fenofibrate results in increased activity of LPL protein |
CTD |
PMID:8593127 PMID:11798191 PMID:16595124 PMID:24752549 PMID:27071702 |
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NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100
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G |
Lrrc31 |
leucine rich repeat containing 31 |
increases expression |
ISO |
Fenofibrate results in increased expression of LRRC31 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 3:30,732,703...30,753,992
Ensembl chr 3:30,732,703...30,753,992
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G |
Lrsam1 |
leucine rich repeat and sterile alpha motif containing 1 |
multiple interactions decreases expression |
EXP |
PPARA protein affects the reaction [Fenofibrate results in decreased expression of LRSAM1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 2:32,815,227...32,851,666
Ensembl chr 2:32,815,228...32,851,626
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Lss |
lanosterol synthase |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of LSS mRNA NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LSS mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LSS mRNA] |
CTD |
PMID:23063693 |
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NCBI chr10:76,367,303...76,392,973
Ensembl chr10:76,367,422...76,392,972
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Ltn1 |
listerin E3 ubiquitin protein ligase 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of LTN1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr16:87,173,539...87,229,504
Ensembl chr16:87,173,539...87,229,500
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Ly6d |
lymphocyte antigen 6 family member D |
increases expression |
EXP |
Fenofibrate results in increased expression of LY6D mRNA |
CTD |
PMID:17118139 |
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NCBI chr15:74,633,905...74,635,416
Ensembl chr15:74,633,905...74,635,469
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G |
Lyrm1 |
LYR motif containing 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of LYRM1 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 7:119,495,038...119,515,979
Ensembl chr 7:119,495,084...119,556,186
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G |
Lyz2 |
lysozyme 2 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of LYZ2 mRNA |
CTD |
PMID:11798191 |
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NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226
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G |
Mafg |
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian) |
decreases expression increases expression |
ISO |
Fenofibrate results in decreased expression of MAFG mRNA Fenofibrate results in increased expression of MAFG mRNA |
CTD |
PMID:25596134 |
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NCBI chr11:120,515,943...120,525,771
Ensembl chr11:120,515,943...120,524,426
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G |
Man1a |
mannosidase 1, alpha |
decreases expression |
ISO |
Fenofibrate results in decreased expression of MAN1A mRNA |
CTD |
PMID:16707586 |
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NCBI chr10:53,780,881...53,952,712
Ensembl chr10:53,780,881...53,952,705
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G |
Man1a2 |
mannosidase, alpha, class 1A, member 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of MAN1A2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 3:100,469,519...100,592,789
Ensembl chr 3:100,469,524...100,592,819
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G |
Maob |
monoamine oxidase B |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of MAOB mRNA |
CTD |
PMID:18253720 |
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NCBI chr X:16,575,520...16,683,605
Ensembl chr X:16,575,521...16,683,605
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G |
Map1lc3a |
microtubule-associated protein 1 light chain 3 alpha |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of MAP1LC3A mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of MAP1LC3A mRNA |
CTD |
PMID:21318169 |
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NCBI chr 2:155,118,284...155,119,993
Ensembl chr 2:155,118,217...155,119,993
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [tyloxapol results in increased lipidation of MAP1LC3B protein] |
CTD |
PMID:36905866 |
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NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499
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G |
Map3k13 |
mitogen-activated protein kinase kinase kinase 13 |
increases expression |
ISO |
Fenofibrate results in increased expression of MAP3K13 mRNA |
CTD |
PMID:32741897 |
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NCBI chr16:21,643,923...21,752,189
Ensembl chr16:21,613,096...21,752,189
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G |
Mat2a |
methionine adenosyltransferase 2A |
decreases expression |
ISO |
Fenofibrate results in decreased expression of MAT2A mRNA |
CTD |
PMID:16569247 |
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NCBI chr 6:72,409,779...72,416,539
Ensembl chr 6:72,409,782...72,416,541
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G |
Mc1r |
melanocortin 1 receptor |
decreases expression multiple interactions |
EXP |
Fenofibrate results in decreased expression of MC1R mRNA [Fenofibrate results in decreased expression of MC1R mRNA] which results in decreased chemical synthesis of Melanins |
CTD |
PMID:23872139 |
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NCBI chr 8:124,133,839...124,137,483
Ensembl chr 8:124,133,846...124,137,483
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G |
Mdh2 |
malate dehydrogenase 2, NAD (mitochondrial) |
increases expression |
ISO |
Fenofibrate results in increased expression of MDH mRNA |
CTD |
PMID:24752549 |
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NCBI chr 5:135,807,503...135,819,240
Ensembl chr 5:135,807,334...135,819,252
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G |
Mdm2 |
transformed mouse 3T3 cell double minute 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of MDM2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663
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G |
Me1 |
malic enzyme 1, NADP(+)-dependent, cytosolic |
affects expression increases expression multiple interactions |
ISO EXP |
Fenofibrate affects the expression of ME1 mRNA Fenofibrate results in increased expression of ME1 mRNA NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA] |
CTD |
PMID:20801182 PMID:23063693 PMID:25596134 PMID:27071702 |
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NCBI chr 9:86,463,416...86,577,967
Ensembl chr 9:86,463,424...86,578,006
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G |
Mertk |
MER proto-oncogene tyrosine kinase |
increases expression |
ISO |
Fenofibrate results in increased expression of MERTK mRNA |
CTD |
PMID:25572481 |
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NCBI chr 2:128,540,836...128,645,082
Ensembl chr 2:128,540,876...128,644,814
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G |
Mfn2 |
mitofusin 2 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of MFN2 protein] |
CTD |
PMID:32730863 |
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NCBI chr 4:147,958,043...147,989,527
Ensembl chr 4:147,958,056...147,989,161
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G |
Mfsd2a |
MFSD2 lysolipid transporter A, lysophospholipid |
decreases expression |
ISO |
Fenofibrate results in decreased expression of MFSD2A mRNA |
CTD |
PMID:25572481 |
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NCBI chr 4:122,840,643...122,855,844
Ensembl chr 4:122,840,643...122,854,981
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G |
Mgll |
monoglyceride lipase |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of MGLL mRNA |
CTD |
PMID:11798191 PMID:17118139 PMID:27665778 |
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NCBI chr 6:88,701,397...88,805,342
Ensembl chr 6:88,701,394...88,805,342
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G |
Mgmt |
O-6-methylguanine-DNA methyltransferase |
multiple interactions increases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of MGMT mRNA Fenofibrate results in increased expression of MGMT mRNA |
CTD |
PMID:17264098 PMID:18253720 |
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NCBI chr 7:136,496,315...136,732,001
Ensembl chr 7:136,496,343...136,731,995
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G |
Mgrn1 |
mahogunin, ring finger 1 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of MGRN1 mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of MGRN1 mRNA |
CTD |
PMID:21318169 |
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NCBI chr16:4,703,964...4,756,160
Ensembl chr16:4,704,113...4,756,160
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G |
Mgst3 |
microsomal glutathione S-transferase 3 |
increases expression |
EXP |
Fenofibrate results in increased expression of MGST3 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 1:167,199,535...167,221,410
Ensembl chr 1:167,199,535...167,221,410
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G |
Mitf |
melanogenesis associated transcription factor |
decreases expression |
EXP |
Fenofibrate results in decreased expression of MITF mRNA; Fenofibrate results in decreased expression of MITF protein |
CTD |
PMID:23872139 |
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NCBI chr 6:97,783,966...97,998,321
Ensembl chr 6:97,784,013...97,998,310
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G |
Mki67 |
antigen identified by monoclonal antibody Ki 67 |
increases expression |
ISO |
Fenofibrate results in increased expression of MKI67 mRNA; Fenofibrate results in increased expression of MKI67 protein |
CTD |
PMID:17264098 PMID:32741897 |
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NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090
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G |
Mlh1 |
mutL homolog 1 |
multiple interactions increases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of MLH1 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of MLH1 mRNA Fenofibrate results in increased expression of MLH1 mRNA |
CTD |
PMID:17264098 PMID:18253720 PMID:18775883 |
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NCBI chr 9:111,057,296...111,100,854
Ensembl chr 9:111,057,296...111,100,859
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G |
Mlycd |
malonyl-CoA decarboxylase |
multiple interactions |
ISO |
[Fenofibrate co-treated with Resveratrol] inhibits the reaction [Fructose results in decreased expression of MLYCD mRNA]; Fenofibrate inhibits the reaction [Fructose results in decreased expression of MLYCD mRNA]; Fenofibrate promotes the reaction [PPARA protein results in increased expression of MLYCD mRNA] |
CTD |
PMID:14641110 PMID:26973390 |
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NCBI chr 8:120,121,591...120,148,577
Ensembl chr 8:120,121,617...120,137,841
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G |
Mmd |
monocyte to macrophage differentiation-associated |
increases expression |
ISO |
Fenofibrate results in increased expression of MMD mRNA |
CTD |
PMID:25572481 |
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NCBI chr11:90,078,513...90,169,399
Ensembl chr11:90,140,282...90,169,415
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G |
Mmp19 |
matrix metallopeptidase 19 |
increases expression |
ISO |
Fenofibrate results in increased expression of MMP19 mRNA |
CTD |
PMID:25596134 |
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NCBI chr10:128,626,779...128,636,696
Ensembl chr10:128,626,779...128,636,693
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G |
Mmp1b |
matrix metallopeptidase 1b (interstitial collagenase) |
decreases expression |
ISO |
Fenofibrate results in decreased expression of MMP1 protein |
CTD |
PMID:25545733 |
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NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
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G |
Mmp2 |
matrix metallopeptidase 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of MMP2 protein |
CTD |
PMID:25545733 |
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NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
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G |
Mmp7 |
matrix metallopeptidase 7 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of MMP7 protein |
CTD |
PMID:25545733 |
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NCBI chr 9:7,692,095...7,699,587
Ensembl chr 9:7,692,091...7,699,587
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions decreases expression |
ISO |
Fenofibrate inhibits the reaction [Dinoprostone results in increased expression of MMP9 mRNA]; Fenofibrate inhibits the reaction [Dinoprostone results in increased secretion of MMP9 protein]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP9 protein] Fenofibrate results in decreased expression of MMP9 protein |
CTD |
PMID:19880272 PMID:21075133 PMID:25545733 |
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NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
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G |
Mrap |
melanocortin 2 receptor accessory protein |
increases expression |
EXP |
Fenofibrate results in increased expression of MRAP mRNA |
CTD |
PMID:11798191 |
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NCBI chr16:90,535,095...90,546,673
Ensembl chr16:90,535,095...90,546,673
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G |
Ms4a10 |
membrane-spanning 4-domains, subfamily A, member 10 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of MS4A10 mRNA |
CTD |
PMID:25572481 |
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NCBI chr19:10,939,653...10,952,088
Ensembl chr19:10,939,657...10,952,034
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G |
Msc |
musculin |
decreases expression |
ISO |
Fenofibrate results in decreased expression of MSC mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:14,823,570...14,826,216
Ensembl chr 1:14,823,570...14,826,216
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G |
Msmo1 |
methylsterol monoxygenase 1 |
affects expression |
ISO |
Fenofibrate affects the expression of MSMO1 mRNA |
CTD |
PMID:20801182 |
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NCBI chr 8:65,171,157...65,186,822
Ensembl chr 8:65,171,173...65,186,826
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G |
Mttp |
microsomal triglyceride transfer protein |
increases expression |
ISO |
Fenofibrate results in increased expression of MTTP mRNA |
CTD |
PMID:32741897 |
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NCBI chr 3:137,795,616...137,849,179
Ensembl chr 3:137,795,615...137,850,729
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G |
Myc |
myelocytomatosis oncogene |
multiple interactions increases expression |
EXP ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of MYC mRNA Fenofibrate results in increased expression of MYC mRNA |
CTD |
PMID:18978307 PMID:32741897 |
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NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
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G |
Mylk |
myosin, light polypeptide kinase |
decreases expression |
ISO |
Fenofibrate results in decreased expression of MYLK mRNA |
CTD |
PMID:25572481 |
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NCBI chr16:34,565,569...34,822,806
Ensembl chr16:34,565,580...34,822,790
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G |
N4bp2l1 |
NEDD4 binding protein 2-like 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of N4BP2L1 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 5:150,495,108...150,518,288
Ensembl chr 5:150,495,109...150,520,653
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G |
Nacc1 |
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing |
increases expression |
ISO |
Fenofibrate results in increased expression of NACC1 mRNA |
CTD |
PMID:17264098 |
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NCBI chr 8:85,397,106...85,414,528
Ensembl chr 8:85,397,108...85,414,531
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G |
Nampt |
nicotinamide phosphoribosyltransferase |
increases expression |
ISO |
Fenofibrate results in increased expression of NAMPT mRNA |
CTD |
PMID:25596134 |
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NCBI chr12:32,870,334...32,903,368
Ensembl chr12:32,869,544...32,903,348
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G |
Nars1 |
asparaginyl-tRNA synthetase 1 |
affects expression |
ISO |
Fenofibrate affects the expression of NARS1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr18:64,632,726...64,649,586
Ensembl chr18:64,632,718...64,649,723
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G |
Nat8f3 |
N-acetyltransferase 8 (GCN5-related) family member 3 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of NAT8F3 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 6:85,737,613...85,742,726
Ensembl chr 6:85,709,495...85,742,736
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Nbn |
nibrin |
multiple interactions increases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of NBN mRNA Fenofibrate results in increased expression of NBN mRNA |
CTD |
PMID:17264098 PMID:18253720 PMID:18775883 |
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NCBI chr 4:15,955,388...15,992,589
Ensembl chr 4:15,957,925...15,992,589
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G |
Nceh1 |
neutral cholesterol ester hydrolase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of NCEH1 mRNA |
CTD |
PMID:27665778 |
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NCBI chr 3:27,237,153...27,299,112
Ensembl chr 3:27,237,114...27,338,757
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G |
Ndufab1 |
NADH:ubiquinone oxidoreductase subunit AB1 |
increases expression |
EXP |
Fenofibrate results in increased expression of NDUFAB1 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 7:121,686,038...121,701,071
Ensembl chr 7:121,684,626...121,701,109
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G |
Neat1 |
nuclear paraspeckle assembly transcript 1 (non-protein coding) |
increases expression |
ISO |
Fenofibrate results in increased expression of NEAT1 mRNA; Fenofibrate results in increased expression of NEAT1 mRNA alternative form |
CTD |
PMID:31311324 |
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NCBI chr19:5,874,736...5,895,508
Ensembl chr19:5,874,736...5,897,132
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G |
Nedd4 |
neural precursor cell expressed, developmentally down-regulated 4 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of NEDD4 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of NEDD4 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 9:72,569,613...72,657,133
Ensembl chr 9:72,569,628...72,657,134
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G |
Nedd9 |
neural precursor cell expressed, developmentally down-regulated gene 9 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of NEDD9 mRNA |
CTD |
PMID:25596134 |
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NCBI chr13:41,463,392...41,640,836
Ensembl chr13:41,463,057...41,640,838
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G |
Nfatc4 |
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4 |
multiple interactions |
ISO |
EDN1 protein promotes the reaction [Fenofibrate promotes the reaction [NFATC4 protein binds to PPARA protein]]; Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]; Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to NPPB promoter]]; Fenofibrate promotes the reaction [NFATC4 protein binds to PPARA protein]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]] |
CTD |
PMID:22198280 |
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NCBI chr14:56,062,252...56,071,400
Ensembl chr14:56,060,601...56,071,400
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G |
Nfe2l2 |
nuclear factor, erythroid derived 2, like 2 |
multiple interactions increases activity decreases expression affects activity |
ISO EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of NFE2L2 protein Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of NFE2L2 protein] Fenofibrate inhibits the reaction [triptolide results in increased expression of NFE2L2 mRNA]; Fenofibrate inhibits the reaction [triptolide results in increased expression of NFE2L2 protein] Fenofibrate results in increased activity of NFE2L2 protein Fenofibrate results in decreased expression of NFE2L2 mRNA Fenofibrate affects the activity of NFE2L2 protein |
CTD |
PMID:18775883 PMID:25596134 PMID:30114225 PMID:30203046 PMID:31241159 PMID:32730863 More...
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NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
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G |
Nfkb1 |
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 |
multiple interactions affects localization |
ISO |
Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of NFKB1 protein] Fenofibrate affects the localization of NFKB1 protein |
CTD |
PMID:20580385 PMID:25545733 |
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NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
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G |
Nfkbia |
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha |
multiple interactions decreases expression |
ISO |
Fenofibrate inhibits the reaction [ALB protein modified form results in increased degradation of NFKBIA protein] Fenofibrate results in decreased expression of NFKBIA protein modified form |
CTD |
PMID:20580385 PMID:25545733 |
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NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
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G |
Nfkbib |
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of NFKBIB mRNA; [Fenofibrate co-treated with Sodium Glutamate] results in increased expression of NFKBIB mRNA |
CTD |
PMID:18253720 PMID:21999347 |
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NCBI chr 7:28,457,676...28,466,069
Ensembl chr 7:28,457,676...28,466,937
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G |
Nim1k |
NIM1 serine/threonine protein kinase |
increases expression |
ISO |
Fenofibrate results in increased expression of NIM1K mRNA |
CTD |
PMID:32741897 |
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NCBI chr13:120,171,630...120,217,418
Ensembl chr13:120,171,630...120,217,418
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G |
Ninj1 |
ninjurin 1 |
affects expression |
ISO |
Fenofibrate affects the expression of NINJ1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr13:49,341,005...49,349,727
Ensembl chr13:49,340,961...49,349,720
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G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [Cyclophosphamide results in increased expression of NLRP3 protein] |
CTD |
PMID:38278497 |
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NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
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G |
Nmur1 |
neuromedin U receptor 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of NMUR1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:86,313,964...86,317,083
Ensembl chr 1:86,314,025...86,353,950
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G |
Nnmt |
nicotinamide N-methyltransferase |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of NNMT mRNA |
CTD |
PMID:18253720 |
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NCBI chr 9:48,448,905...48,518,958
Ensembl chr 9:48,503,177...48,516,453
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G |
Nos2 |
nitric oxide synthase 2, inducible |
multiple interactions |
EXP ISO |
Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] [Fenofibrate co-treated with Sodium Glutamate] results in increased expression of NOS2 mRNA; [Fenofibrate co-treated with Sodium Glutamate] results in increased expression of NOS2 protein |
CTD |
PMID:21300114 PMID:21999347 |
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NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
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G |
Nos3 |
nitric oxide synthase 3, endothelial cell |
multiple interactions increases phosphorylation increases activity |
ISO |
dorsomorphin inhibits the reaction [Fenofibrate results in increased activity of NOS3 protein]; Fenofibrate inhibits the reaction [Wortmannin results in decreased phosphorylation of NOS3 protein]; PRKAA1 protein affects the reaction [Fenofibrate results in increased activity of NOS3 protein] Fenofibrate results in increased phosphorylation of NOS3 protein |
CTD |
PMID:16442496 PMID:20580385 |
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NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472
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G |
Notch1 |
notch 1 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [triptolide results in increased expression of NOTCH1 mRNA] |
CTD |
PMID:31241159 |
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NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675
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G |
Notch3 |
notch 3 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [triptolide results in increased expression of NOTCH3 mRNA]; Fenofibrate inhibits the reaction [triptolide results in increased expression of NOTCH3 protein] |
CTD |
PMID:31241159 |
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NCBI chr17:32,339,794...32,385,869
Ensembl chr17:32,339,794...32,385,826
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G |
Nppa |
natriuretic peptide type A |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [Doxorubicin results in decreased expression of NPPA mRNA] |
CTD |
PMID:17531194 |
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NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536
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G |
Nppb |
natriuretic peptide type B |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to NPPB promoter]]; Fenofibrate inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]] |
CTD |
PMID:22198280 |
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NCBI chr 4:148,070,264...148,071,662
Ensembl chr 4:148,070,245...148,071,662
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G |
Nr0b2 |
nuclear receptor subfamily 0, group B, member 2 |
multiple interactions increases expression |
ISO EXP |
Dactinomycin inhibits the reaction [Fenofibrate results in increased expression of NR0B2 mRNA]; dorsomorphin inhibits the reaction [Fenofibrate results in increased expression of NR0B2 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD4 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]]; pyrazolanthrone inhibits the reaction [Fenofibrate results in increased expression of NR0B2 mRNA] [Methionine deficiency co-treated with Choline deficiency co-treated with Fenofibrate] results in increased expression of NR0B2 mRNA; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of IL6 mRNA]]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 mRNA]]; NR0B2 protein promotes the reaction [[Methionine deficiency co-treated with Choline deficiency co-treated with Fenofibrate] results in increased expression of CYP4A14 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of FAS mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SREBF1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TGFB1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF mRNA]] Fenofibrate results in increased expression of NR0B2 mRNA; Fenofibrate results in increased expression of NR0B2 protein |
CTD |
PMID:19593819 |
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NCBI chr 4:133,280,687...133,283,997
Ensembl chr 4:133,280,687...133,283,847
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G |
Nr1h2 |
nuclear receptor subfamily 1, group H, member 2 |
increases expression multiple interactions |
ISO EXP |
Fenofibrate results in increased expression of NR1H2 mRNA NR1H2 gene mutant form affects the reaction [Fenofibrate results in increased expression of ACACB mRNA]; NR1H2 gene mutant form affects the reaction [Fenofibrate results in increased expression of SCD1 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A10 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A14 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FDFT1 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of HMGCR mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LSS mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of PPARA mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SQLE mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SREBF1 mRNA] |
CTD |
PMID:19201410 PMID:23063693 |
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NCBI chr 7:44,199,040...44,204,928
Ensembl chr 7:44,199,040...44,203,375
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G |
Nr1h3 |
nuclear receptor subfamily 1, group H, member 3 |
increases expression multiple interactions affects response to substance |
ISO EXP |
Fenofibrate results in increased expression of NR1H3 mRNA NR1H3 gene mutant form affects the reaction [Fenofibrate results in increased expression of ACACB mRNA]; NR1H3 gene mutant form affects the reaction [Fenofibrate results in increased expression of SCD1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A10 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A14 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FDFT1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of HMGCR mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LSS mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of PPARA mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SQLE mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SREBF1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of NR1H3 mRNA] NR1H3 protein affects the susceptibility to Fenofibrate [Oleic Acid co-treated with Fenofibrate] affects the expression of NR1H3 mRNA; NR1H3 protein affects the reaction [Fenofibrate results in increased expression of PPARA mRNA] |
CTD |
PMID:19201410 PMID:23063693 PMID:24534255 PMID:25949234 |
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NCBI chr 2:91,014,406...91,033,189
Ensembl chr 2:91,014,406...91,033,179
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
multiple interactions increases expression |
ISO |
[Oleic Acid co-treated with Fenofibrate] results in decreased expression of NR1H4 mRNA fenofibrate increases expression of Nr1h4 mRNA in steatotic liver |
CTD RGD |
PMID:24534255 PMID:30257410 |
RGD:15090799 |
NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
multiple interactions |
ISO |
Fenofibrate binds to and results in increased activity of NR1I2 protein |
CTD |
PMID:20024649 |
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NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186
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G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
affects localization increases activity multiple interactions increases expression |
EXP ISO |
Fenofibrate affects the localization of NR1I3 protein Fenofibrate results in increased activity of NR1I3 protein [Oleic Acid co-treated with Fenofibrate] results in increased expression of NR1I3 mRNA; Fenofibrate binds to and results in increased activity of NR1I3 protein alternative form Fenofibrate results in increased expression of NR1I3 mRNA |
CTD |
PMID:17962186 PMID:19118567 PMID:24534255 PMID:30203046 PMID:31312845 PMID:32741897 More...
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NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270
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G |
Nr4a1 |
nuclear receptor subfamily 4, group A, member 1 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]] |
CTD |
PMID:19593819 |
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NCBI chr15:101,151,783...101,172,676
Ensembl chr15:101,152,150...101,172,676
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G |
Nrep |
neuronal regeneration related protein |
decreases expression |
ISO |
Fenofibrate results in decreased expression of NREP mRNA |
CTD |
PMID:25596134 |
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NCBI chr18:33,570,072...33,597,444
Ensembl chr18:33,570,072...33,597,082
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G |
Nsdhl |
NAD(P) dependent steroid dehydrogenase-like |
increases expression |
EXP |
Fenofibrate results in increased expression of NSDHL mRNA |
CTD |
PMID:11798191 |
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NCBI chr X:71,962,127...72,002,134
Ensembl chr X:71,962,163...72,002,120
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G |
Ntpcr |
nucleoside-triphosphatase, cancer-related |
affects expression |
ISO |
Fenofibrate affects the expression of NTPCR mRNA |
CTD |
PMID:25596134 |
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NCBI chr 8:126,456,724...126,474,974
Ensembl chr 8:126,456,702...126,474,974
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G |
Nuak1 |
NUAK family, SNF1-like kinase, 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of NUAK1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr10:84,206,764...84,282,028
Ensembl chr10:84,206,769...84,276,461
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G |
Oasl1 |
2'-5' oligoadenylate synthetase-like 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of OASL mRNA |
CTD |
PMID:25572481 |
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NCBI chr 5:115,061,236...115,075,970
Ensembl chr 5:115,061,299...115,075,974
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G |
Opa1 |
OPA1, mitochondrial dynamin like GTPase |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of OPA1 protein] |
CTD |
PMID:32730863 |
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NCBI chr16:29,398,099...29,481,924
Ensembl chr16:29,398,152...29,473,702
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G |
Orai3 |
ORAI calcium release-activated calcium modulator 3 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ORAI3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 7:127,368,987...127,374,322
Ensembl chr 7:127,368,987...127,374,322
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G |
Orm2 |
orosomucoid 2 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of ORM2 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 4:63,280,543...63,284,114
Ensembl chr 4:63,280,686...63,284,115
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G |
Osgin1 |
oxidative stress induced growth inhibitor 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of OSGIN1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 8:120,160,874...120,172,996
Ensembl chr 8:120,160,863...120,172,995
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G |
P4ha1 |
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide |
affects expression |
ISO |
Fenofibrate affects the expression of P4HA1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr10:59,159,019...59,209,126
Ensembl chr10:59,159,118...59,209,126
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G |
P4hb |
prolyl 4-hydroxylase, beta polypeptide |
affects expression |
ISO |
Fenofibrate affects the expression of P4HB mRNA |
CTD |
PMID:20801182 |
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NCBI chr11:120,451,124...120,464,079
Ensembl chr11:120,451,124...120,464,079
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G |
Pank1 |
pantothenate kinase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of PANK1 mRNA |
CTD |
PMID:16707586 PMID:25572481 PMID:25596134 |
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NCBI chr19:34,784,335...34,862,420
Ensembl chr19:34,784,340...34,856,855
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G |
Pbk |
PDZ binding kinase |
increases expression |
ISO |
Fenofibrate results in increased expression of PBK mRNA |
CTD |
PMID:32741897 |
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NCBI chr14:66,043,337...66,055,271
Ensembl chr14:66,043,286...66,055,271
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G |
Pck1 |
phosphoenolpyruvate carboxykinase 1, cytosolic |
increases expression |
ISO |
Fenofibrate results in increased expression of PCK1 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066
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G |
Pck2 |
phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
increases expression |
ISO |
Fenofibrate results in increased expression of PCK2 mRNA |
CTD |
PMID:16569247 PMID:24752549 |
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NCBI chr14:55,777,721...55,787,477
Ensembl chr14:55,777,723...55,788,699
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G |
Pcna |
proliferating cell nuclear antigen |
multiple interactions increases expression |
EXP ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of PCNA protein Fenofibrate results in increased expression of PCNA protein ESR1 protein inhibits the reaction [Fenofibrate results in increased expression of PCNA protein]; Estradiol inhibits the reaction [Fenofibrate results in increased expression of PCNA protein] |
CTD |
PMID:18978307 PMID:29134746 |
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NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
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G |
Pcsk9 |
proprotein convertase subtilisin/kexin type 9 |
increases expression |
ISO |
Fenofibrate results in increased expression of PCSK9 protein |
CTD |
PMID:21411093 |
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NCBI chr 4:106,299,531...106,321,522
Ensembl chr 4:106,299,526...106,321,526
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G |
Pdia5 |
protein disulfide isomerase associated 5 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of PDIA5 mRNA |
CTD |
PMID:25596134 |
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NCBI chr16:35,217,678...35,311,289
Ensembl chr16:35,217,682...35,311,243
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G |
Pdk1 |
pyruvate dehydrogenase kinase, isoenzyme 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of PDK1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 2:71,703,398...71,734,202
Ensembl chr 2:71,703,568...71,734,202
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G |
Pdk4 |
pyruvate dehydrogenase kinase, isoenzyme 4 |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of PDK4 mRNA |
CTD |
PMID:17118139 PMID:19395589 PMID:25572481 PMID:25596134 PMID:27665778 PMID:32741897 More...
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NCBI chr 6:5,483,351...5,496,278
Ensembl chr 6:5,483,351...5,496,309
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G |
Pdlim1 |
PDZ and LIM domain 1 (elfin) |
decreases expression |
ISO |
Fenofibrate results in decreased expression of PDLIM1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr19:40,210,683...40,260,060
Ensembl chr19:40,209,617...40,260,286
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G |
Pdrg1 |
p53 and DNA damage regulated 1 |
multiple interactions decreases expression |
EXP |
PPARA protein affects the reaction [Fenofibrate results in decreased expression of PDRG1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 2:152,850,810...152,857,939
Ensembl chr 2:152,850,810...152,857,347
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G |
Pemt |
phosphatidylethanolamine N-methyltransferase |
increases expression |
ISO |
Fenofibrate results in increased expression of PEMT mRNA |
CTD |
PMID:25572481 |
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NCBI chr11:59,861,440...59,937,394
Ensembl chr11:59,861,440...59,937,315
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G |
Pex11a |
peroxisomal biogenesis factor 11 alpha |
affects expression increases expression |
ISO |
Fenofibrate affects the expression of PEX11A mRNA Fenofibrate results in increased expression of PEX11A mRNA |
CTD |
PMID:20801182 PMID:25572481 PMID:27665778 PMID:32741897 |
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NCBI chr 7:79,385,705...79,392,879
Ensembl chr 7:79,385,705...79,392,879
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G |
Pgm1 |
phosphoglucomutase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of PGM1 mRNA |
CTD |
PMID:24752549 |
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NCBI chr 4:99,786,648...99,844,491
Ensembl chr 4:99,786,611...99,844,491
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G |
Phgdh |
3-phosphoglycerate dehydrogenase |
increases expression |
ISO |
Fenofibrate results in increased expression of PHGDH mRNA |
CTD |
PMID:25596134 |
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NCBI chr 3:98,220,487...98,247,285
Ensembl chr 3:98,220,486...98,247,306
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G |
Phlda1 |
pleckstrin homology like domain, family A, member 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of PHLDA1 mRNA |
CTD |
PMID:11798191 |
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NCBI chr10:111,342,147...111,344,510
Ensembl chr10:111,342,147...111,344,506
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G |
Phlda3 |
pleckstrin homology like domain, family A, member 3 |
affects expression |
ISO |
Fenofibrate affects the expression of PHLDA3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:135,693,823...135,696,872
Ensembl chr 1:135,693,857...135,696,874
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G |
Pik3c2g |
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma |
decreases expression |
ISO |
Fenofibrate results in decreased expression of PIK3C2G mRNA |
CTD |
PMID:16707586 |
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NCBI chr 6:139,591,070...139,915,010
Ensembl chr 6:139,564,219...139,915,010
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G |
Pir |
pirin |
decreases expression |
ISO |
Fenofibrate results in decreased expression of PIR mRNA |
CTD |
PMID:25596134 |
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NCBI chr X:163,052,427...163,156,009
Ensembl chr X:163,052,367...163,156,007
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G |
Pja2 |
praja ring finger ubiquitin ligase 2 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of PJA2 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of PJA2 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr17:64,588,001...64,638,878
Ensembl chr17:64,588,000...64,638,911
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G |
Pkib |
protein kinase inhibitor beta, cAMP dependent, testis specific |
increases expression |
ISO |
Fenofibrate results in increased expression of PKIB mRNA |
CTD |
PMID:25572481 |
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NCBI chr10:57,508,077...57,617,208
Ensembl chr10:57,508,077...57,617,208
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G |
Pklr |
pyruvate kinase liver and red blood cell |
decreases expression |
ISO |
Fenofibrate results in decreased expression of PKLR mRNA |
CTD |
PMID:25572481 |
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NCBI chr 3:89,043,429...89,054,122
Ensembl chr 3:89,043,449...89,054,091
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G |
Pla1a |
phospholipase A1 member A |
increases expression |
ISO |
Fenofibrate results in increased expression of PLA1A mRNA |
CTD |
PMID:25572481 |
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NCBI chr16:38,214,245...38,253,553
Ensembl chr16:38,216,479...38,253,507
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G |
Pla2g7 |
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
decreases activity multiple interactions |
ISO |
Fenofibrate results in decreased activity of PLA2G7 protein [orlistat co-treated with Fenofibrate] results in decreased activity of PLA2G7 protein |
CTD |
PMID:16911813 |
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NCBI chr17:43,879,009...43,923,093
Ensembl chr17:43,878,989...43,923,092
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G |
Plcxd3 |
phosphatidylinositol-specific phospholipase C, X domain containing 3 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of PLCXD3 mRNA |
CTD |
PMID:25572481 |
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NCBI chr15:4,404,973...4,605,067
Ensembl chr15:4,404,973...4,605,035
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G |
Plin1 |
perilipin 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of PLIN1 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 7:79,370,912...79,382,652
Ensembl chr 7:79,369,966...79,382,651
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G |
Plin2 |
perilipin 2 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of PLIN2 mRNA Fenofibrate promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA] |
CTD |
PMID:24534255 PMID:25572481 PMID:25596134 PMID:27665778 |
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NCBI chr 4:86,545,147...86,588,518
Ensembl chr 4:86,566,623...86,588,297
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G |
Plin4 |
perilipin 4 |
increases expression |
ISO |
Fenofibrate results in increased expression of PLIN4 mRNA |
CTD |
PMID:25572481 |
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NCBI chr17:56,407,587...56,416,947
Ensembl chr17:56,407,591...56,416,803
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G |
Plin5 |
perilipin 5 |
increases expression |
ISO |
Fenofibrate results in increased expression of PLIN5 mRNA |
CTD |
PMID:32741897 |
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NCBI chr17:56,418,601...56,424,606
Ensembl chr17:56,418,601...56,424,596
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G |
Pltp |
phospholipid transfer protein |
increases expression |
EXP |
Fenofibrate results in increased expression of PLTP mRNA |
CTD |
PMID:11798191 |
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NCBI chr 2:164,681,441...164,699,564
Ensembl chr 2:164,681,438...164,699,631
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G |
Pmepa1 |
prostate transmembrane protein, androgen induced 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of PMEPA1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 2:173,066,251...173,118,329
Ensembl chr 2:173,066,251...173,118,326
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G |
Pml |
promyelocytic leukemia |
multiple interactions |
ISO |
Fenofibrate promotes the reaction [Arsenic Trioxide results in decreased expression of PML protein mutant form] |
CTD |
PMID:32929351 |
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NCBI chr 9:58,125,359...58,157,077
Ensembl chr 9:58,125,359...58,157,069
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G |
Podxl |
podocalyxin-like |
decreases expression |
ISO |
Fenofibrate results in decreased expression of PODXL mRNA |
CTD |
PMID:25596134 |
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NCBI chr 6:31,496,428...31,540,872
Ensembl chr 6:31,496,423...31,540,916
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G |
Pon1 |
paraoxonase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of PON1 protein |
CTD |
PMID:16123850 |
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NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946
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G |
Por |
cytochrome p450 oxidoreductase |
increases expression |
ISO |
Fenofibrate results in increased expression of POR mRNA |
CTD |
PMID:16707586 PMID:25572481 |
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NCBI chr 5:135,698,894...135,764,180
Ensembl chr 5:135,698,887...135,764,180
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G |
Ppan |
peter pan homolog |
affects expression |
ISO |
Fenofibrate affects the expression of PPAN mRNA |
CTD |
PMID:25596134 |
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NCBI chr 9:20,799,471...20,803,475
Ensembl chr 9:20,799,471...20,803,474
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
decreases expression multiple interactions increases response to substance decreases response to substance increases activity increases expression affects response to substance |
ISO EXP |
Fenofibrate results in decreased expression of PPARA mRNA fenofibrate co-treated with fructose diet decreases expression of ppara mRNA in liver PPARA protein results in increased susceptibility to Fenofibrate PPARA gene mutant form results in decreased susceptibility to Fenofibrate Fenofibrate results in increased activity of PPARA protein [Fenofibrate co-treated with Fatty Acids, Nonesterified] results in increased expression of PPARA mRNA; ESR1 protein inhibits the reaction [Estradiol inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]]; ESR1 protein inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]; Estradiol inhibits the reaction [ESR1 protein inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]]; Estradiol inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]; Fenofibrate binds to and results in increased activity of PPARA protein; Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of PPARA mRNA]; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of PPARA protein]; NR1H3 protein affects the reaction [Fenofibrate results in increased expression of PPARA mRNA]; PPARA protein inhibits the reaction [Fenofibrate results in decreased expression of APOA1 mRNA]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of ACOX1 protein]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of ACSL1 protein]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of LPL protein]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of SLC27A4 protein]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of UCP2 protein] [Fenofibrate binds to and results in increased activity of PPARA protein] which affects the abundance of Fatty Acids, Nonesterified; [Fenofibrate binds to and results in increased activity of PPARA protein] which affects the abundance of Triglycerides; [Fenofibrate results in increased activity of PPARA protein] which results in decreased abundance of Adenosine Triphosphate; [Fenofibrate results in increased activity of PPARA protein] which results in increased expression of TRIB3 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of ASB6 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of BRCC3 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC14 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC19 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC2 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of FKBP15 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of HECTD1 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of HSPB8 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of MAP1LC3A mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of MGRN1 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of PRKAB2 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of SEC63 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of SMPD3 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of TOPORS mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of UBR2 mRNA; Fenofibrate binds to and results in increased activity of PPARA protein; Fenofibrate inhibits the reaction [Zoledronic Acid results in decreased expression of PPARA mRNA]; Fenofibrate promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Fenofibrate results in increased expression of and results in increased activity of PPARA protein; Lipopolysaccharides inhibits the reaction [Fenofibrate results in increased expression of PPARA mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of PPARA mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of PPARA mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACB mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACLY mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 protein]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACSL1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACSL1 protein]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A10 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A14 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LPL mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LPL protein]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of NR1H3 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SLC27A4 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SLC27A4 protein]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of UCP2 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of UCP2 protein]; PPARA promotes the reaction [Fenofibrate results in decreased expression of FGA mRNA]; PPARA protein affects the reaction [Fenofibrate affects the expression of BRAP mRNA]; PPARA protein affects the reaction [Fenofibrate promotes the reaction [APOA1 protein results in increased secretion of Lipids]]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of ANAPC11 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of CISH mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of CYLD mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of DNAJB4 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of HSPA13 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of ITCH mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of LNX1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of LRSAM1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of PDRG1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of PPP3CA mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of PRKAB1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of RBJ mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of RNF144B mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of UBE2R2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of URM1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of USP36 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of WSB1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ACADM mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ARIH1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ATE1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ATG12 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ATG7 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of CANX mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of CBLB mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of CNOT4 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJA2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJB6 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJC3 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJC5 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ENC1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO3 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO30 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO32 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of FOXO1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of GRPEL2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSP90AA1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSP90AB1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA4L mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA8 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA9 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPB1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPH1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of NEDD4 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of PJA2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of PPP1R15B mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMB2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMC6 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMD4 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of RABGEF1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of RNF14 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of SENP2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of SOCS6 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of SPOP mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of TOR1B mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of TOR3A mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of TRIM63 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of TRIP12 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of UBE2Q2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of UBE3A mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of URI1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP10 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP22 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP38 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP7 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP9X mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USPL1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of VCPIP1 mRNA] Fenofibrate results in increased expression of PPARA mRNA; Fenofibrate results in increased expression of PPARA protein PPARA protein results in increased susceptibility to Fenofibrate; PPARA results in increased susceptibility to Fenofibrate [Fenofibrate binds to and results in increased activity of PPARA protein] which results in increased expression of UCP2 mRNA; EDN1 protein promotes the reaction [Fenofibrate promotes the reaction [NFATC4 protein binds to PPARA protein]]; Fenofibrate binds to and results in increased activity of PPARA protein; Fenofibrate inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PPARA protein]; Fenofibrate inhibits the reaction [Fructose results in decreased expression of and results in decreased activity of PPARA protein]; Fenofibrate inhibits the reaction [Pyrazinamide results in decreased expression of PPARA mRNA]; Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of PPARA mRNA]; Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of PPARA protein]; Fenofibrate promotes the reaction [NFATC4 protein binds to PPARA protein]; Fenofibrate promotes the reaction [PPARA protein results in increased expression of MLYCD mRNA]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]] |
CTD RGD |
PMID:7983038 PMID:10216095 PMID:11341955 PMID:11798191 PMID:11934685 PMID:12759900 PMID:14641110 PMID:15299082 PMID:15968640 PMID:16569247 PMID:17201732 PMID:17655842 PMID:18300857 PMID:18338635 PMID:18356826 PMID:18812576 PMID:19118567 PMID:19124612 PMID:19201410 PMID:19445040 PMID:19569716 PMID:19593819 PMID:20520642 PMID:21300114 PMID:21318169 PMID:22198280 PMID:23063693 PMID:24735863 PMID:24752549 PMID:24986865 PMID:25035112 PMID:25689681 PMID:25949234 PMID:26989860 PMID:27071702 PMID:28743512 PMID:28871336 PMID:29134746 PMID:30203046 PMID:30611848 PMID:33408297 PMID:11934685 More...
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RGD:628329 |
NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
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G |
Ppard |
peroxisome proliferator activator receptor delta |
increases expression multiple interactions |
EXP ISO |
Fenofibrate results in increased expression of PPARD mRNA Fenofibrate inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PPARD protein] |
CTD |
PMID:18338635 PMID:19201410 |
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NCBI chr17:28,451,715...28,520,446
Ensembl chr17:28,451,674...28,520,448
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G |
Pparg |
peroxisome proliferator activated receptor gamma |
increases expression affects activity multiple interactions |
ISO EXP |
Fenofibrate results in increased expression of PPARG mRNA Fenofibrate affects the activity of PPARG protein [Oleic Acid co-treated with Fenofibrate] results in increased expression of PPARG mRNA |
CTD |
PMID:19201410 PMID:24534255 PMID:25596134 PMID:28034800 |
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NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
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G |
Ppargc1a |
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha |
multiple interactions |
EXP ISO |
Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of PPARGC1A mRNA] Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of PPARGC1A protein] |
CTD |
PMID:28871336 PMID:32730863 |
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NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068
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G |
Ppcs |
phosphopantothenoylcysteine synthetase |
increases expression |
ISO |
Fenofibrate results in increased expression of PPCS mRNA |
CTD |
PMID:27665778 |
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NCBI chr 4:119,275,724...119,279,673
Ensembl chr 4:119,275,727...119,279,617
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G |
Ppm1d |
protein phosphatase 1D magnesium-dependent, delta isoform |
decreases expression |
ISO |
Fenofibrate results in decreased expression of PPM1D mRNA |
CTD |
PMID:25596134 |
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NCBI chr11:85,202,080...85,237,897
Ensembl chr11:85,202,070...85,237,892
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G |
Ppp1r15a |
protein phosphatase 1, regulatory subunit 15A |
increases expression decreases expression |
ISO |
Fenofibrate results in increased expression of PPP1R15A mRNA Fenofibrate results in decreased expression of PPP1R15A mRNA |
CTD |
PMID:25596134 |
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NCBI chr 7:45,172,341...45,175,692
Ensembl chr 7:45,172,340...45,175,692
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G |
Ppp1r15b |
protein phosphatase 1, regulatory subunit 15B |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of PPP1R15B mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of PPP1R15B mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 1:133,058,904...133,067,538
Ensembl chr 1:133,058,881...133,067,521
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G |
Ppp3ca |
protein phosphatase 3, catalytic subunit, alpha isoform |
multiple interactions decreases expression |
EXP |
PPARA protein affects the reaction [Fenofibrate results in decreased expression of PPP3CA mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 3:136,375,778...136,643,488
Ensembl chr 3:136,375,885...136,643,488
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G |
Prkaa1 |
protein kinase, AMP-activated, alpha 1 catalytic subunit |
multiple interactions decreases response to substance |
ISO |
PRKAA1 protein affects the reaction [Fenofibrate results in decreased susceptibility to ALB protein modified form]; PRKAA1 protein affects the reaction [Fenofibrate results in increased abundance of Nitric Oxide]; PRKAA1 protein affects the reaction [Fenofibrate results in increased activity of NOS3 protein] PRKAA1 gene mutant form results in decreased susceptibility to Fenofibrate |
CTD |
PMID:20580385 PMID:25545733 |
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NCBI chr15:5,172,641...5,211,380
Ensembl chr15:5,173,343...5,211,380
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G |
Prkab1 |
protein kinase, AMP-activated, beta 1 non-catalytic subunit |
decreases expression increases phosphorylation multiple interactions |
EXP ISO |
Fenofibrate results in decreased expression of PRKAB1 mRNA Fenofibrate results in increased phosphorylation of PRKAB1 protein PPARA protein affects the reaction [Fenofibrate results in decreased expression of PRKAB1 mRNA] |
CTD |
PMID:21318169 PMID:25545733 |
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NCBI chr 5:116,151,654...116,162,449
Ensembl chr 5:116,151,645...116,162,567
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G |
Prkab2 |
protein kinase, AMP-activated, beta 2 non-catalytic subunit |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of PRKAB2 mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of PRKAB2 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 3:97,565,527...97,581,128
Ensembl chr 3:97,565,509...97,581,128
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G |
Prkag1 |
protein kinase, AMP-activated, gamma 1 non-catalytic subunit |
increases expression |
ISO |
Fenofibrate results in increased expression of PRKAG1 protein |
CTD |
PMID:25545733 |
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NCBI chr15:98,710,678...98,729,354
Ensembl chr15:98,710,678...98,729,402
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G |
Prodh |
proline dehydrogenase |
decreases expression |
ISO |
Fenofibrate results in decreased expression of PRODH mRNA |
CTD |
PMID:25572481 |
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NCBI chr16:17,889,593...17,907,147
Ensembl chr16:17,878,221...17,908,067
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G |
Prrg4 |
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
increases expression |
ISO |
Fenofibrate results in increased expression of PRRG4 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 2:104,657,374...104,680,216
Ensembl chr 2:104,661,086...104,680,221
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G |
Psen1 |
presenilin 1 |
multiple interactions |
ISO |
Fenofibrate affects the reaction [PSEN1 protein affects the cleavage of APP protein] |
CTD |
PMID:17962197 |
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NCBI chr12:83,734,926...83,781,869
Ensembl chr12:83,734,926...83,781,973
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G |
Psmb2 |
proteasome (prosome, macropain) subunit, beta type 2 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of PSMB2 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMB2 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 4:126,571,460...126,603,503
Ensembl chr 4:126,571,423...126,603,507
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G |
Psmc6 |
proteasome (prosome, macropain) 26S subunit, ATPase, 6 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of PSMC6 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMC6 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr14:45,567,285...45,587,150
Ensembl chr14:45,567,245...45,587,162
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G |
Psmd4 |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of PSMD4 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMD4 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 3:94,939,999...94,949,880
Ensembl chr 3:94,940,005...94,949,925
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G |
Ptgs1 |
prostaglandin-endoperoxide synthase 1 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of PTGS1 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] |
CTD |
PMID:21300114 |
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NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
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G |
Ptprf |
protein tyrosine phosphatase receptor type F |
affects expression |
ISO |
Fenofibrate affects the expression of PTPRF mRNA |
CTD |
PMID:20801182 |
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NCBI chr 4:118,065,410...118,148,602
Ensembl chr 4:118,065,410...118,148,602
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G |
Ptprq |
protein tyrosine phosphatase receptor type Q |
decreases expression |
ISO |
Fenofibrate results in decreased expression of PTPRQ mRNA |
CTD |
PMID:25572481 |
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NCBI chr10:107,350,224...107,555,939
Ensembl chr10:107,352,910...107,555,912
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G |
Pygl |
liver glycogen phosphorylase |
increases expression |
ISO |
Fenofibrate results in increased expression of PYGL mRNA |
CTD |
PMID:25596134 |
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NCBI chr12:70,237,589...70,274,457
Ensembl chr12:70,237,585...70,278,262
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G |
Qpct |
glutaminyl-peptide cyclotransferase (glutaminyl cyclase) |
increases expression |
ISO |
Fenofibrate results in increased expression of QPCT mRNA |
CTD |
PMID:27665778 PMID:32741897 |
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NCBI chr17:79,359,335...79,397,807
Ensembl chr17:79,359,335...79,397,807
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G |
Rab30 |
RAB30, member RAS oncogene family |
increases expression |
ISO |
Fenofibrate results in increased expression of RAB30 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 7:92,390,845...92,493,743
Ensembl chr 7:92,390,811...92,493,743
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G |
Rab31 |
RAB31, member RAS oncogene family |
decreases expression |
ISO |
Fenofibrate results in decreased expression of RAB31 mRNA |
CTD |
PMID:25596134 |
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NCBI chr17:65,958,721...66,079,747
Ensembl chr17:65,958,724...66,079,747
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G |
Rabgef1 |
RAB guanine nucleotide exchange factor (GEF) 1 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of RABGEF1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of RABGEF1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 5:130,200,644...130,243,178
Ensembl chr 5:130,200,639...130,243,183
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G |
Rad50 |
RAD50 double strand break repair protein |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of RAD50 mRNA |
CTD |
PMID:18253720 |
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NCBI chr11:53,540,346...53,598,146
Ensembl chr11:53,540,346...53,598,146
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G |
Rad51b |
RAD51 paralog B |
increases expression |
EXP |
Fenofibrate results in increased expression of RAD51B mRNA |
CTD |
PMID:11798191 |
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NCBI chr12:79,344,032...79,895,034
Ensembl chr12:79,344,056...79,861,464
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G |
Raet1e |
retinoic acid early transcript 1E |
increases expression |
EXP |
Fenofibrate results in increased expression of RAET1E mRNA |
CTD |
PMID:11798191 |
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NCBI chr10:22,034,441...22,059,820
Ensembl chr10:22,034,468...22,250,038
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G |
Ramp2 |
receptor (calcitonin) activity modifying protein 2 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of RAMP2 mRNA |
CTD |
PMID:11798191 |
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NCBI chr11:101,137,160...101,139,076
Ensembl chr11:101,136,854...101,150,372
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G |
Rara |
retinoic acid receptor, alpha |
multiple interactions decreases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of RARA mRNA Fenofibrate results in decreased expression of RARA mRNA |
CTD |
PMID:18253720 PMID:25596134 |
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NCBI chr11:98,818,626...98,865,768
Ensembl chr11:98,818,644...98,865,768
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G |
Rarb |
retinoic acid receptor, beta |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of RARB mRNA |
CTD |
PMID:18253720 |
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NCBI chr14:5,387,365...6,038,924
Ensembl chr14:5,650,540...6,038,924
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G |
Rbp2 |
retinol binding protein 2, cellular |
increases expression |
ISO |
Fenofibrate results in increased expression of RBP2 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 9:98,372,590...98,391,824
Ensembl chr 9:98,368,168...98,391,834
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G |
Rbx1 |
ring-box 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of RBX1 mRNA |
CTD |
PMID:21318169 |
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NCBI chr15:81,350,517...81,360,570
Ensembl chr15:81,350,497...81,360,570
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G |
Rdh16 |
retinol dehydrogenase 16 |
increases expression |
EXP |
Fenofibrate results in increased expression of RDH16 mRNA |
CTD |
PMID:11798191 |
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NCBI chr10:127,636,959...127,651,715
Ensembl chr10:127,637,021...127,682,434
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G |
Rela |
v-rel reticuloendotheliosis viral oncogene homolog A (avian) |
multiple interactions |
ISO |
Fenofibrate affects the localization of and results in decreased activity of RELA protein; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of RELA protein]; Fenofibrate inhibits the reaction [Glucose results in increased expression of RELA protein]; Fenofibrate results in decreased localization of and results in decreased activity of RELA protein [Fenofibrate co-treated with Sodium Glutamate] results in increased expression of RELA protein; Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of RELA protein]; Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of RELA protein]; Fenofibrate promotes the reaction [Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of RELA protein]]; Pioglitazone promotes the reaction [Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of RELA protein]] |
CTD |
PMID:16600694 PMID:20520642 PMID:20580385 PMID:21999347 PMID:25545733 PMID:36988379 PMID:38216941 More...
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NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
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G |
Retn |
resistin |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Arsenic Trioxide results in increased expression of and results in increased secretion of RETN protein] |
CTD |
PMID:32929351 |
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NCBI chr 8:3,705,770...3,709,818
Ensembl chr 8:3,705,770...3,710,110
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G |
Retsat |
retinol saturase (all trans retinol 13,14 reductase) |
increases expression |
EXP |
Fenofibrate results in increased expression of RETSAT mRNA |
CTD |
PMID:11798191 |
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NCBI chr 6:72,575,585...72,584,471
Ensembl chr 6:72,575,458...72,585,408
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G |
Rgs16 |
regulator of G-protein signaling 16 |
increases expression |
ISO |
Fenofibrate results in increased expression of RGS16 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 1:153,616,099...153,621,212
Ensembl chr 1:153,616,095...153,621,214
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G |
Rhof |
ras homolog family member F (in filopodia) |
increases expression |
ISO |
Fenofibrate results in increased expression of RHOF mRNA |
CTD |
PMID:32741897 |
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NCBI chr 5:123,256,243...123,270,692
Ensembl chr 5:123,241,107...123,270,755
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G |
Rlf |
rearranged L-myc fusion sequence |
increases expression |
ISO |
Fenofibrate results in increased expression of RLF mRNA |
CTD |
PMID:25596134 |
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NCBI chr 4:121,003,080...121,072,318
Ensembl chr 4:121,002,570...121,072,281
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G |
Rnd1 |
Rho family GTPase 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of RND1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr15:98,567,086...98,575,342
Ensembl chr15:98,561,302...98,575,342
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G |
Rnd3 |
Rho family GTPase 3 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of RND3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 2:51,020,451...51,039,123
Ensembl chr 2:51,020,450...51,039,123
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G |
Rnf125 |
ring finger protein 125 |
increases expression |
EXP |
Fenofibrate results in increased expression of RNF125 mRNA |
CTD |
PMID:21318169 |
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NCBI chr18:21,077,672...21,120,416
Ensembl chr18:21,077,682...21,116,919
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G |
Rnf14 |
ring finger protein 14 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of RNF14 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of RNF14 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr18:38,410,513...38,450,905
Ensembl chr18:38,417,590...38,450,902
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G |
Rnf144b |
ring finger protein 144B |
decreases expression multiple interactions |
EXP |
Fenofibrate results in decreased expression of RNF144B mRNA PPARA protein affects the reaction [Fenofibrate results in decreased expression of RNF144B mRNA] |
CTD |
PMID:21318169 |
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NCBI chr13:47,276,196...47,401,470
Ensembl chr13:47,276,132...47,401,467
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G |
Rnf19a |
ring finger protein 19A |
increases expression |
EXP |
Fenofibrate results in increased expression of RNF19A mRNA |
CTD |
PMID:21318169 |
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NCBI chr15:36,240,080...36,283,293
Ensembl chr15:36,240,079...36,283,293
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G |
Ro60 |
Ro60, Y RNA binding protein |
decreases expression |
ISO |
Fenofibrate results in decreased expression of RO60 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:143,626,528...143,652,794
Ensembl chr 1:143,626,528...143,652,806
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G |
Rsrc2 |
arginine/serine-rich coiled-coil 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of RSRC2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 5:123,866,489...123,887,522
Ensembl chr 5:123,866,489...123,887,477
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G |
Rxra |
retinoid X receptor alpha |
decreases expression affects expression |
ISO |
Fenofibrate results in decreased expression of RXRA mRNA Fenofibrate affects the expression of RXRA mRNA |
CTD |
PMID:25596134 |
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NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969
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G |
S100a10 |
S100 calcium binding protein A10 (calpactin) |
increases expression |
EXP |
Fenofibrate results in increased expression of S100A10 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 3:93,462,424...93,471,952
Ensembl chr 3:93,462,387...93,471,950
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G |
Saa1 |
serum amyloid A 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of SAA1 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 7:46,389,921...46,392,404
Ensembl chr 7:46,389,921...46,392,404
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G |
Saa2 |
serum amyloid A 2 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of SAA2 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 7:46,401,257...46,403,737
Ensembl chr 7:46,401,214...46,403,737
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G |
Saa3 |
serum amyloid A 3 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of SAA3 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 7:46,361,422...46,365,100
Ensembl chr 7:46,361,422...46,365,124
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G |
Sars1 |
seryl-tRNA synthetase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of SARS1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 3:108,332,180...108,352,575
Ensembl chr 3:108,332,181...108,352,525
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G |
Sat1 |
spermidine/spermine N1-acetyl transferase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of SAT1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr X:153,996,128...153,999,345
Ensembl chr X:153,996,128...153,999,445
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G |
Scamp1 |
secretory carrier membrane protein 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of SCAMP1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr13:94,337,818...94,422,339
Ensembl chr13:94,337,818...94,422,365
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G |
Scarb1 |
scavenger receptor class B, member 1 |
multiple interactions decreases activity increases expression |
ISO EXP |
[Aspirin co-treated with Fenofibrate] results in increased expression of SCARB1 protein Fenofibrate results in decreased activity of SCARB1 protein Fenofibrate inhibits the reaction [SCARB1 protein results in increased export of Cholesterol, HDL]; Fenofibrate inhibits the reaction [SCARB1 protein results in increased uptake of cholesteryl oleyl ether] Fenofibrate results in increased expression of SCARB1 protein |
CTD |
PMID:16816107 PMID:17533223 |
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NCBI chr 5:125,354,151...125,418,082
Ensembl chr 5:125,354,151...125,418,158
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G |
Scd1 |
stearoyl-Coenzyme A desaturase 1 |
multiple interactions affects expression increases expression |
EXP ISO |
NR1H2 gene mutant form affects the reaction [Fenofibrate results in increased expression of SCD1 mRNA]; NR1H3 gene mutant form affects the reaction [Fenofibrate results in increased expression of SCD1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD1 mRNA] Fenofibrate affects the expression of SCD mRNA |
CTD |
PMID:23063693 PMID:27665778 |
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NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318
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G |
Scd2 |
stearoyl-Coenzyme A desaturase 2 |
increases expression multiple interactions |
EXP ISO |
Fenofibrate results in increased expression of SCD mRNA; Fenofibrate results in increased expression of SCD2 mRNA [Oleic Acid co-treated with Fenofibrate] results in increased expression of SCD1 mRNA NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA] |
CTD |
PMID:17118139 PMID:23063693 PMID:24534255 |
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NCBI chr19:44,282,115...44,295,303
Ensembl chr19:44,282,113...44,295,303
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G |
Scly |
selenocysteine lyase |
affects expression |
ISO |
Fenofibrate affects the expression of SCLY mRNA |
CTD |
PMID:20801182 |
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NCBI chr 1:91,226,017...91,248,797
Ensembl chr 1:91,226,060...91,248,797
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G |
Sdhb |
succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
increases expression |
ISO |
Fenofibrate results in increased expression of SDHB protein |
CTD |
PMID:24752549 |
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NCBI chr 4:140,688,582...140,706,509
Ensembl chr 4:140,688,514...140,706,504
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G |
Sec63 |
SEC63 homolog, protein translocation regulator |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of SEC63 mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of SEC63 mRNA |
CTD |
PMID:21318169 |
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NCBI chr10:42,637,492...42,708,510
Ensembl chr10:42,637,492...42,708,510
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G |
Sele |
selectin, endothelial cell |
multiple interactions |
ISO |
dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of SELE mRNA]]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of SELE mRNA] |
CTD |
PMID:20580385 |
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NCBI chr 1:163,867,200...163,886,056
Ensembl chr 1:163,875,773...163,885,246
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G |
Sema6b |
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B |
multiple interactions decreases expression |
ISO |
alitretinoin promotes the reaction [Fenofibrate results in decreased expression of SEMA6B mRNA]; alitretinoin promotes the reaction [Fenofibrate results in decreased expression of SEMA6B protein] Fenofibrate results in decreased expression of SEMA6B mRNA; Fenofibrate results in decreased expression of SEMA6B protein |
CTD |
PMID:16525649 |
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NCBI chr17:56,430,085...56,447,343
Ensembl chr17:56,430,085...56,447,343
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G |
Senp2 |
SUMO/sentrin specific peptidase 2 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of SENP2 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of SENP2 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr16:21,828,182...21,868,019
Ensembl chr16:21,828,234...21,868,019
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G |
Serpina3k |
serine (or cysteine) peptidase inhibitor, clade A, member 3K |
decreases expression |
EXP |
Fenofibrate results in decreased expression of SERPINA3K mRNA |
CTD |
PMID:11798191 |
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NCBI chr12:104,304,745...104,311,998
Ensembl chr12:104,304,745...104,312,403
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G |
Serpina3n |
serine (or cysteine) peptidase inhibitor, clade A, member 3N |
affects expression |
ISO |
Fenofibrate affects the expression of SERPINA3N mRNA |
CTD |
PMID:20801182 |
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NCBI chr12:104,372,967...104,380,588
Ensembl chr12:104,372,988...104,380,588
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G |
Serpine1 |
serine (or cysteine) peptidase inhibitor, clade E, member 1 |
multiple interactions affects expression |
ISO EXP |
Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [SMAD4 protein results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD4 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]] [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of SERPINE1 mRNA Fenofibrate affects the expression of SERPINE1 mRNA Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA]] |
CTD |
PMID:18253720 PMID:19593819 PMID:20801182 |
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NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122
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G |
Sertad1 |
SERTA domain containing 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of SERTAD1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 7:27,186,378...27,189,741
Ensembl chr 7:27,186,335...27,189,741
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G |
Sesn1 |
sestrin 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of SESN1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr10:41,686,570...41,784,432
Ensembl chr10:41,685,931...41,784,420
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G |
Sgk2 |
serum/glucocorticoid regulated kinase 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of SGK2 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 2:162,829,249...162,856,059
Ensembl chr 2:162,829,250...162,856,047
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G |
Sh3bgrl2 |
SH3 domain binding glutamic acid-rich protein like 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of SH3BGRL2 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 9:83,430,391...83,482,345
Ensembl chr 9:83,430,380...83,520,854
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G |
Sh3tc1 |
SH3 domain and tetratricopeptide repeats 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of SH3TC1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 5:35,854,524...35,897,331
Ensembl chr 5:35,854,524...35,897,331
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G |
Siah2 |
siah E3 ubiquitin protein ligase 2 |
affects expression |
ISO |
Fenofibrate affects the expression of SIAH2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 3:58,582,370...58,599,857
Ensembl chr 3:58,582,359...58,599,821
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G |
Sik1 |
salt inducible kinase 1 |
increases expression decreases expression |
ISO |
Fenofibrate results in increased expression of SIK1 mRNA Fenofibrate results in decreased expression of SIK1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr17:32,063,222...32,074,808
Ensembl chr17:32,063,224...32,074,778
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G |
Sirt1 |
sirtuin 1 |
multiple interactions increases expression |
ISO EXP |
dorsomorphin inhibits the reaction [Fenofibrate results in increased expression of SIRT1 protein]; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of SIRT1 protein]; zinc protoporphyrin inhibits the reaction [Fenofibrate results in increased expression of SIRT1 protein] |
CTD |
PMID:32730863 PMID:34520103 |
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NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483
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G |
Siva1 |
SIVA1, apoptosis-inducing factor |
decreases expression |
ISO |
Fenofibrate results in decreased expression of SIVA1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr12:112,611,262...112,615,586
Ensembl chr12:112,611,113...112,615,583
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G |
Slc10a1 |
solute carrier family 10 (sodium/bile acid cotransporter family), member 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of SLC10A1 mRNA |
CTD |
PMID:25572481 PMID:27765674 |
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NCBI chr12:80,999,959...81,015,479
Ensembl chr12:80,999,957...81,015,479
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G |
Slc16a13 |
solute carrier family 16 (monocarboxylic acid transporters), member 13 |
increases expression |
ISO |
Fenofibrate results in increased expression of SLC16A13 mRNA |
CTD |
PMID:25572481 |
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NCBI chr11:70,107,615...70,113,638
Ensembl chr11:70,107,615...70,111,890
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G |
Slc16a6 |
solute carrier family 16 (monocarboxylic acid transporters), member 6 |
increases expression |
ISO |
Fenofibrate results in increased expression of SLC16A6 mRNA |
CTD |
PMID:25596134 |
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NCBI chr11:109,341,681...109,366,428
Ensembl chr11:109,341,681...109,364,424
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G |
Slc1a7 |
solute carrier family 1 (glutamate transporter), member 7 |
increases expression |
ISO |
Fenofibrate results in increased expression of SLC1A7 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 4:107,825,603...107,870,726
Ensembl chr 4:107,825,529...107,870,729
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G |
Slc22a5 |
solute carrier family 22 (organic cation transporter), member 5 |
increases expression |
ISO |
Fenofibrate results in increased expression of SLC22A5 mRNA |
CTD |
PMID:27665778 PMID:32741897 |
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NCBI chr11:53,755,368...53,782,609
Ensembl chr11:53,755,368...53,782,486
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G |
Slc25a20 |
solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 |
increases expression |
ISO |
Fenofibrate results in increased expression of SLC25A20 mRNA |
CTD |
PMID:16707586 PMID:25572481 PMID:25596134 |
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NCBI chr 9:108,539,335...108,561,841
Ensembl chr 9:108,539,287...108,561,840
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G |
Slc25a30 |
solute carrier family 25, member 30 |
increases expression |
ISO |
Fenofibrate results in increased expression of SLC25A30 mRNA |
CTD |
PMID:32741897 |
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NCBI chr14:75,994,986...76,024,477
Ensembl chr14:75,997,557...76,024,477
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G |
Slc25a34 |
solute carrier family 25, member 34 |
increases expression |
ISO |
Fenofibrate results in increased expression of SLC25A34 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 4:141,346,130...141,351,202
Ensembl chr 4:141,346,135...141,351,132
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G |
Slc25a4 |
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of SLC25A4 protein |
CTD |
PMID:20118634 |
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NCBI chr 8:46,660,205...46,664,099
Ensembl chr 8:46,659,834...46,664,321
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G |
Slc27a1 |
solute carrier family 27 (fatty acid transporter), member 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of SLC27A1 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 8:72,021,372...72,039,951
Ensembl chr 8:72,021,526...72,039,946
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Slc27a2 |
solute carrier family 27 (fatty acid transporter), member 2 |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of SLC27A2 mRNA |
CTD |
PMID:17118139 PMID:25572481 PMID:27665778 PMID:32741897 PMID:32741898 |
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NCBI chr 2:126,394,944...126,430,163
Ensembl chr 2:126,394,327...126,430,163
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Slc27a4 |
solute carrier family 27 (fatty acid transporter), member 4 |
increases expression multiple interactions |
ISO EXP |
Fenofibrate results in increased expression of SLC27A4 mRNA; Fenofibrate results in increased expression of SLC27A4 protein PPARA protein promotes the reaction [Fenofibrate results in increased expression of SLC27A4 protein] PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SLC27A4 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SLC27A4 protein] |
CTD |
PMID:24752549 |
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NCBI chr 2:29,692,646...29,707,534
Ensembl chr 2:29,692,646...29,707,534
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Slc34a2 |
solute carrier family 34 (sodium phosphate), member 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of SLC34A2 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 5:53,206,695...53,229,006
Ensembl chr 5:53,195,423...53,229,006
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Slc3a2 |
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of SLC3A2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr19:8,684,931...8,700,733
Ensembl chr19:8,684,246...8,700,733
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Slc6a9 |
solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
decreases expression increases expression |
ISO |
Fenofibrate results in decreased expression of SLC6A9 mRNA Fenofibrate results in increased expression of SLC6A9 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 4:117,692,240...117,726,502
Ensembl chr 4:117,691,703...117,732,395
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G |
Slc7a1 |
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of SLC7A1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 5:148,264,220...148,336,714
Ensembl chr 5:148,264,220...148,336,714
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G |
Slc7a5 |
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 |
increases expression |
ISO |
Fenofibrate results in increased expression of SLC7A5 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 8:122,607,885...122,634,425
Ensembl chr 8:122,607,889...122,634,433
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G |
Slco2b1 |
solute carrier organic anion transporter family, member 2b1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of SLCO2B1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 7:99,307,011...99,360,547
Ensembl chr 7:99,307,011...99,360,547
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G |
Smad3 |
SMAD family member 3 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]] |
CTD |
PMID:19593819 |
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NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276
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G |
Smad4 |
SMAD family member 4 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [SMAD4 protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD4 protein results in increased expression of SERPINE1 mRNA]] |
CTD |
PMID:19593819 |
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NCBI chr18:73,767,861...73,836,862
Ensembl chr18:73,772,080...73,836,851
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G |
Smpd2 |
sphingomyelin phosphodiesterase 2, neutral |
multiple interactions |
EXP |
Fenofibrate promotes the reaction [Dextran Sulfate results in decreased expression of SMPD2 mRNA] |
CTD |
PMID:25035112 |
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NCBI chr10:41,363,168...41,366,410
Ensembl chr10:41,361,638...41,366,365
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G |
Smpd3 |
sphingomyelin phosphodiesterase 3, neutral |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of SMPD3 mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of SMPD3 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 8:106,979,180...107,064,597
Ensembl chr 8:106,979,180...107,064,620
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G |
Smpd4 |
sphingomyelin phosphodiesterase 4 |
multiple interactions |
EXP |
Fenofibrate promotes the reaction [Dextran Sulfate results in decreased expression of SMPD4 mRNA] |
CTD |
PMID:25035112 |
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NCBI chr16:17,437,218...17,462,694
Ensembl chr16:17,437,218...17,462,692
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G |
Socs3 |
suppressor of cytokine signaling 3 |
multiple interactions |
ISO |
[Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in increased expression of SOCS3 mRNA]; Fenofibrate inhibits the reaction [Fructose results in increased expression of SOCS3 mRNA] |
CTD |
PMID:26973390 |
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NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873
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G |
Socs6 |
suppressor of cytokine signaling 6 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of SOCS6 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of SOCS6 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr18:88,883,293...88,912,623
Ensembl chr18:88,683,348...88,945,605
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G |
Socs7 |
suppressor of cytokine signaling 7 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of SOCS7 mRNA |
CTD |
PMID:21318169 |
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NCBI chr11:97,253,044...97,289,368
Ensembl chr11:97,253,261...97,289,368
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G |
Sod2 |
superoxide dismutase 2, mitochondrial |
increases expression |
ISO |
Fenofibrate results in increased expression of SOD2 mRNA |
CTD |
PMID:17264098 |
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NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
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G |
Son |
Son DNA binding protein |
decreases expression |
ISO |
Fenofibrate results in decreased expression of SON mRNA |
CTD |
PMID:25596134 |
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NCBI chr16:91,444,712...91,476,080
Ensembl chr16:91,444,394...91,476,109
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G |
Sorl1 |
sortilin-related receptor, LDLR class A repeats-containing |
increases expression decreases expression |
ISO |
Fenofibrate results in increased expression of SORL1 mRNA Fenofibrate results in decreased expression of SORL1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 9:41,876,005...42,035,593
Ensembl chr 9:41,876,016...42,035,593
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G |
Sort1 |
sortilin 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of SORT1 mRNA |
CTD |
PMID:24986865 |
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NCBI chr 3:108,191,272...108,268,835
Ensembl chr 3:108,191,398...108,268,827
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G |
Spmip11 |
sperm microtubule inner protein 11 |
increases expression |
ISO |
Fenofibrate results in increased expression of SPMIP11 mRNA |
CTD |
PMID:32741897 |
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NCBI chr15:98,468,885...98,487,469
Ensembl chr15:98,468,885...98,487,461
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G |
Spns2 |
SPNS lysolipid transporter 2, sphingosine-1-phosphate |
increases expression |
ISO |
Fenofibrate results in increased expression of SPNS2 mRNA |
CTD |
PMID:25572481 |
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NCBI chr11:72,342,464...72,380,797
Ensembl chr11:72,342,464...72,380,730
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G |
Spop |
speckle-type BTB/POZ protein |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of SPOP mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of SPOP mRNA] |
CTD |
PMID:21318169 |
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NCBI chr11:95,304,909...95,384,236
Ensembl chr11:95,304,906...95,384,232
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G |
Spsb1 |
splA/ryanodine receptor domain and SOCS box containing 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of SPSB1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 4:149,980,740...150,039,494
Ensembl chr 4:149,980,740...150,039,500
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G |
Sqle |
squalene epoxidase |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of SQLE mRNA NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SQLE mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SQLE mRNA] |
CTD |
PMID:23063693 |
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NCBI chr15:59,186,941...59,203,042
Ensembl chr15:59,186,926...59,203,041
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G |
Sqstm1 |
sequestosome 1 |
increases expression multiple interactions |
ISO EXP |
Fenofibrate results in increased expression of SQSTM1 mRNA Fenofibrate inhibits the reaction [tyloxapol results in increased expression of SQSTM1 protein] |
CTD |
PMID:25596134 PMID:36905866 |
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NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654
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G |
Srd5a3 |
steroid 5 alpha-reductase 3 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of SRD5A3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 5:76,285,296...76,303,350
Ensembl chr 5:76,288,118...76,303,351
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
multiple interactions increases expression |
EXP ISO |
Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SREBF1 mRNA]; Fenofibrate inhibits the reaction [tyloxapol results in increased expression of SREBF1 protein]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SREBF1 mRNA]]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SREBF1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SREBF1 mRNA] Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in increased expression of SREBF1 mRNA]; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in increased expression of SREBF1 protein] [Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in increased expression of SREBF1 mRNA] |
CTD |
PMID:19593819 PMID:23063693 PMID:24735863 PMID:26973390 PMID:36905866 |
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NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407
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G |
Srxn1 |
sulfiredoxin 1 homolog (S. cerevisiae) |
increases expression |
ISO |
Fenofibrate results in increased expression of SRXN1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 2:151,946,738...151,953,296
Ensembl chr 2:151,947,436...151,953,296
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G |
St3gal4 |
ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of ST3GAL4 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 9:34,957,872...35,028,160
Ensembl chr 9:34,957,872...35,030,564
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G |
Stat5b |
signal transducer and activator of transcription 5B |
decreases activity |
EXP |
Fenofibrate results in decreased activity of STAT5B protein |
CTD |
PMID:30114225 |
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NCBI chr11:100,671,557...100,741,407
Ensembl chr11:100,671,557...100,741,550
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G |
Stk11 |
serine/threonine kinase 11 |
multiple interactions |
ISO |
Fenofibrate results in increased expression of and results in increased phosphorylation of STK11 protein |
CTD |
PMID:25545733 |
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NCBI chr10:79,951,602...79,966,513
Ensembl chr10:79,951,637...79,966,516
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G |
Strbp |
spermatid perinuclear RNA binding protein |
increases expression |
ISO |
Fenofibrate results in increased expression of STRBP mRNA |
CTD |
PMID:25596134 |
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NCBI chr 2:37,459,880...37,593,890
Ensembl chr 2:37,373,240...37,593,871
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G |
Suclg1 |
succinate-CoA ligase, GDP-forming, alpha subunit |
affects expression increases expression |
ISO |
Fenofibrate affects the expression of SUCLG1 mRNA Fenofibrate results in increased expression of SUCLG1 protein Fenofibrate results in increased expression of SUCLG1 mRNA |
CTD |
PMID:16707586 PMID:20801182 PMID:24752549 |
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NCBI chr 6:73,225,488...73,253,890
Ensembl chr 6:73,225,365...73,253,894
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G |
Sulf2 |
sulfatase 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of SULF2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 2:165,915,819...165,997,603
Ensembl chr 2:165,915,009...165,997,583
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G |
Sult1c2 |
sulfotransferase family, cytosolic, 1C, member 2 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of SULT1C2 mRNA |
CTD |
PMID:18253720 |
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NCBI chr17:54,136,665...54,152,986
Ensembl chr17:54,136,665...54,153,367
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G |
Sult1e1 |
sulfotransferase family 1E, member 1 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of SULT1E1 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 5:87,723,827...87,739,470
Ensembl chr 5:87,723,828...87,739,453
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Sult4a1 |
sulfotransferase family 4A, member 1 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of SULT4A1 mRNA |
CTD |
PMID:18253720 |
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NCBI chr15:83,960,298...83,989,955
Ensembl chr15:83,960,298...83,989,955
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Taldo1 |
transaldolase 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of TALDO1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 7:140,972,073...140,982,889
Ensembl chr 7:140,972,112...140,982,881
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Tars1 |
threonyl-tRNA synthetase 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of TARS1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr15:11,383,749...11,399,744
Ensembl chr15:11,382,387...11,399,751
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Tcp1 |
t-complex protein 1 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of TCP1 mRNA |
CTD |
PMID:18253720 |
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NCBI chr17:13,135,216...13,143,954
Ensembl chr17:13,134,588...13,143,954
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G |
Tdo2 |
tryptophan 2,3-dioxygenase |
increases expression |
ISO |
Fenofibrate results in increased expression of TDO2 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 3:81,865,719...81,883,035
Ensembl chr 3:81,864,397...81,883,509
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G |
Tfe3 |
transcription factor E3 |
affects expression increases expression |
ISO |
Fenofibrate affects the expression of TFE3 mRNA Fenofibrate results in increased expression of TFE3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr X:7,628,769...7,641,441
Ensembl chr X:7,628,799...7,641,441
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Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
ISO EXP |
Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]] [Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in increased expression of TGFB1 mRNA]; Fenofibrate inhibits the reaction [Fructose results in increased expression of TGFB1 mRNA] Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TGFB1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in decreased expression of TRIB3 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of IL6 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 mRNA]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of IL6 mRNA]]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TGFB1 mRNA]] |
CTD |
PMID:19593819 PMID:26973390 PMID:32613381 |
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NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
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G |
Thrsp |
thyroid hormone responsive |
multiple interactions decreases expression |
ISO |
Fenofibrate promotes the reaction [Oleic Acid results in decreased expression of THRSP mRNA] Fenofibrate results in decreased expression of THRSP mRNA |
CTD |
PMID:24534255 PMID:25572481 |
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NCBI chr 7:97,062,140...97,066,757
Ensembl chr 7:97,062,145...97,066,937
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G |
Timp1 |
tissue inhibitor of metalloproteinase 1 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 mRNA]; Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of TIMP1 mRNA]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]] |
CTD |
PMID:19593819 PMID:28871336 |
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NCBI chr X:20,736,524...20,740,972
Ensembl chr X:20,736,405...20,740,974
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G |
Timp2 |
tissue inhibitor of metalloproteinase 2 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of TIMP2 mRNA] |
CTD |
PMID:28871336 |
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NCBI chr11:118,191,887...118,246,237
Ensembl chr11:118,191,887...118,246,566
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G |
Tiparp |
TCDD-inducible poly(ADP-ribose) polymerase |
increases expression |
ISO |
Fenofibrate results in increased expression of TIPARP mRNA |
CTD |
PMID:25596134 |
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NCBI chr 3:65,435,868...65,462,939
Ensembl chr 3:65,435,831...65,462,939
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G |
Tlr4 |
toll-like receptor 4 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [Cyclophosphamide results in increased expression of TLR4 protein] |
CTD |
PMID:38278497 |
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NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
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G |
Tmem120a |
transmembrane protein 120A |
decreases expression increases expression |
ISO |
Fenofibrate results in decreased expression of TMEM120A mRNA Fenofibrate results in increased expression of TMEM120A mRNA |
CTD |
PMID:25572481 PMID:32741897 |
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NCBI chr 5:135,764,344...135,773,026
Ensembl chr 5:135,764,339...135,773,302
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G |
Tnf |
tumor necrosis factor |
multiple interactions decreases expression decreases response to substance |
ISO EXP |
Fenofibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Fenofibrate inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; Fenofibrate inhibits the reaction [TNF protein results in increased expression of CCL5 protein]; Fenofibrate inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]] [Fenofibrate co-treated with Resveratrol] inhibits the reaction [Fructose results in increased expression of and results in increased secretion of TNF protein]; [Fenofibrate co-treated with Sodium Glutamate] results in increased expression of TNF protein; Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Fenofibrate inhibits the reaction [Fructose results in increased expression of and results in increased secretion of TNF protein]; Fenofibrate promotes the reaction [Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of TNF protein]]; Pioglitazone promotes the reaction [Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of TNF protein]] Fenofibrate results in decreased expression of TNF mRNA; Fenofibrate results in decreased expression of TNF protein [Fenofibrate co-treated with Alitretinoin] inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF mRNA]; Fenofibrate inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Fenofibrate inhibits the reaction [triptolide results in increased expression of TNF mRNA]; Fenofibrate promotes the reaction [Dextran Sulfate results in increased expression of TNF protein]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF mRNA]] Fenofibrate results in decreased susceptibility to TNF protein; TNF protein results in decreased susceptibility to Fenofibrate |
CTD |
PMID:12586603 PMID:15968640 PMID:18356826 PMID:19593819 PMID:20520642 PMID:21300114 PMID:21999347 PMID:25035112 PMID:26973390 PMID:31241159 PMID:32613381 PMID:36988379 PMID:38278497 More...
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NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
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G |
Tnfrsf11b |
tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) |
decreases expression |
ISO |
Fenofibrate results in decreased expression of TNFRSF11B mRNA |
CTD |
PMID:25572481 |
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NCBI chr15:54,114,014...54,141,700
Ensembl chr15:54,114,015...54,141,880
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G |
Tnfrsf21 |
tumor necrosis factor receptor superfamily, member 21 |
increases expression |
ISO |
Fenofibrate results in increased expression of TNFRSF21 mRNA |
CTD |
PMID:25572481 PMID:25596134 |
|
NCBI chr17:43,327,446...43,400,079
Ensembl chr17:43,327,446...43,400,080
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G |
Tnni3 |
troponin I, cardiac 3 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [Cyclophosphamide results in increased expression of TNNI3 protein] |
CTD |
PMID:38278497 |
|
NCBI chr 7:4,521,304...4,526,228
Ensembl chr 7:4,521,304...4,527,228
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G |
Top1 |
topoisomerase (DNA) I |
multiple interactions increases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of TOP1 mRNA Fenofibrate results in increased expression of TOP1 mRNA |
CTD |
PMID:18253720 PMID:25596134 |
|
NCBI chr 2:160,487,901...160,564,684
Ensembl chr 2:160,487,808...160,564,684
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G |
Top2a |
topoisomerase (DNA) II alpha |
increases expression |
ISO |
Fenofibrate results in increased expression of TOP2A mRNA |
CTD |
PMID:32741897 |
|
NCBI chr11:98,883,773...98,915,037
Ensembl chr11:98,883,769...98,915,015
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G |
Topors |
topoisomerase I binding, arginine/serine-rich |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of TOPORS mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of TOPORS mRNA |
CTD |
PMID:21318169 |
|
NCBI chr 4:40,259,606...40,269,841
Ensembl chr 4:40,259,601...40,269,850
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G |
Tor1b |
torsin family 1, member B |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of TOR1B mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of TOR1B mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr 2:30,842,951...30,854,085
Ensembl chr 2:30,842,971...30,849,027
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G |
Tor3a |
torsin family 3, member A |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of TOR3A mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of TOR3A mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr 1:156,481,187...156,501,909
Ensembl chr 1:156,481,187...156,501,926
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G |
Trafd1 |
TRAF type zinc finger domain containing 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of TRAFD1 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 5:121,509,788...121,524,543
Ensembl chr 5:121,509,788...121,523,695
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G |
Triap1 |
TP53 regulated inhibitor of apoptosis 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of TRIAP1 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 5:115,479,290...115,481,612
Ensembl chr 5:115,479,284...115,481,628
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G |
Trib3 |
tribbles pseudokinase 3 |
multiple interactions decreases expression |
EXP ISO |
[Fenofibrate results in increased activity of PPARA protein] which results in increased expression of TRIB3 mRNA; Fenofibrate inhibits the reaction [TGFB1 protein results in decreased expression of TRIB3 mRNA] Fenofibrate results in decreased expression of TRIB3 mRNA Fenofibrate inhibits the reaction [Arsenic Trioxide results in increased expression of TRIB3 mRNA]; Fenofibrate inhibits the reaction [Arsenic Trioxide results in increased expression of TRIB3 protein] |
CTD |
PMID:19593819 PMID:32929351 |
|
NCBI chr 2:152,179,345...152,185,980
Ensembl chr 2:152,179,342...152,185,952
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G |
Trim24 |
tripartite motif-containing 24 |
increases expression |
ISO |
Fenofibrate results in increased expression of TRIM24 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 6:37,846,816...37,945,380
Ensembl chr 6:37,847,746...37,943,231
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G |
Trim63 |
tripartite motif-containing 63 |
multiple interactions increases expression |
EXP |
Lovastatin promotes the reaction [Fenofibrate results in increased expression of TRIM63 protein]; PPARA protein affects the reaction [Fenofibrate results in increased expression of TRIM63 mRNA] Fenofibrate results in increased expression of TRIM63 mRNA; Fenofibrate results in increased expression of TRIM63 protein |
CTD |
PMID:33408297 |
|
NCBI chr 4:134,042,431...134,056,940
Ensembl chr 4:134,042,431...134,056,940
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G |
Trip12 |
thyroid hormone receptor interactor 12 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of TRIP12 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of TRIP12 mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr 1:84,698,910...84,818,285
Ensembl chr 1:84,698,910...84,818,237
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G |
Trp53 |
transformation related protein 53 |
increases expression affects activity |
ISO |
Fenofibrate results in increased expression of TP53 mRNA Fenofibrate affects the activity of TP53 protein |
CTD |
PMID:17264098 PMID:25596134 |
|
NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
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G |
Trp53inp1 |
transformation related protein 53 inducible nuclear protein 1 |
increases expression affects expression decreases expression |
ISO |
Fenofibrate results in increased expression of TRP53INP1 mRNA Fenofibrate affects the expression of TP53INP1 mRNA Fenofibrate results in decreased expression of TP53INP1 mRNA |
CTD |
PMID:17264098 PMID:25596134 |
|
NCBI chr 4:11,156,441...11,174,379
Ensembl chr 4:11,156,431...11,174,379
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G |
Txnip |
thioredoxin interacting protein |
increases expression |
ISO |
Fenofibrate results in increased expression of TXNIP mRNA |
CTD |
PMID:17264098 PMID:25572481 |
|
NCBI chr 3:96,465,273...96,469,173
Ensembl chr 3:96,465,273...96,469,199
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G |
Txnrd1 |
thioredoxin reductase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of TXNRD1 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr10:82,669,785...82,733,558
Ensembl chr10:82,669,785...82,733,546
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G |
Tyr |
tyrosinase |
multiple interactions decreases expression |
EXP |
[Fenofibrate results in decreased chemical synthesis of Melanins] which results in decreased expression of TYR; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Fenofibrate results in decreased expression of TYR protein]; Fenofibrate results in decreased expression of and results in decreased activity of TYR protein Fenofibrate results in decreased expression of TYR mRNA |
CTD |
PMID:23872139 |
|
NCBI chr 7:87,073,979...87,142,637
Ensembl chr 7:87,073,979...87,142,720
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G |
Uba5 |
ubiquitin-like modifier activating enzyme 5 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of UBA5 mRNA |
CTD |
PMID:21318169 |
|
NCBI chr 9:103,923,786...103,940,767
Ensembl chr 9:103,923,798...103,940,333
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G |
Ube2g2 |
ubiquitin-conjugating enzyme E2G 2 |
affects expression |
ISO |
Fenofibrate affects the expression of UBE2G2 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr10:77,458,155...77,481,824
Ensembl chr10:77,458,109...77,481,827
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G |
Ube2q2 |
ubiquitin-conjugating enzyme E2Q family member 2 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of UBE2Q2 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of UBE2Q2 mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr 9:55,056,602...55,114,813
Ensembl chr 9:55,056,138...55,114,813
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G |
Ube2r2 |
ubiquitin-conjugating enzyme E2R 2 |
decreases expression multiple interactions |
EXP |
Fenofibrate results in decreased expression of UBE2R2 mRNA PPARA protein affects the reaction [Fenofibrate results in decreased expression of UBE2R2 mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr 4:41,136,021...41,193,370
Ensembl chr 4:41,135,743...41,193,380
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G |
Ube2w |
ubiquitin-conjugating enzyme E2W (putative) |
increases expression |
EXP |
Fenofibrate results in increased expression of UBE2W mRNA |
CTD |
PMID:21318169 |
|
NCBI chr 1:16,611,012...16,689,676
Ensembl chr 1:16,611,014...16,689,713
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G |
Ube3a |
ubiquitin protein ligase E3A |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of UBE3A mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of UBE3A mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr 7:58,871,891...58,960,585
Ensembl chr 7:58,878,498...58,961,284
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G |
Ubr2 |
ubiquitin protein ligase E3 component n-recognin 2 |
multiple interactions increases expression |
EXP |
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of UBR2 mRNA Fenofibrate results in increased expression of UBR2 mRNA |
CTD |
PMID:21318169 |
|
NCBI chr17:47,239,217...47,321,812
Ensembl chr17:47,239,221...47,321,482
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G |
Ucp2 |
uncoupling protein 2 (mitochondrial, proton carrier) |
multiple interactions increases expression |
ISO EXP |
[Fenofibrate binds to and results in increased activity of PPARA protein] which results in increased expression of UCP2 mRNA; [Fenofibrate co-treated with Sodium Glutamate] results in increased expression of UCP2 mRNA PPARA protein promotes the reaction [Fenofibrate results in increased expression of UCP2 protein] PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of UCP2 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of UCP2 protein] Fenofibrate results in increased expression of UCP2 mRNA; Fenofibrate results in increased expression of UCP2 protein |
CTD |
PMID:11341955 PMID:16595124 PMID:21999347 PMID:24752549 PMID:32741897 |
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NCBI chr 7:100,142,565...100,148,832
Ensembl chr 7:100,142,544...100,151,227
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G |
Ucp3 |
uncoupling protein 3 (mitochondrial, proton carrier) |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of UCP3 mRNA fenofibrate co-treated with fructose increases expression of Ucp3 mRNA in liver and muscle fenofibrate increases expression of Ucp3 mRNA in muscle |
CTD RGD |
PMID:16595124 PMID:11934685 PMID:11934685 |
RGD:628329, RGD:628329 |
NCBI chr 7:100,122,198...100,135,639
Ensembl chr 7:100,122,197...100,135,639
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G |
Ugt1a1 |
UDP glucuronosyltransferase 1 family, polypeptide A1 |
increases expression |
ISO |
Fenofibrate results in increased expression of UGT1A1 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719
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G |
Ugt1a2 |
UDP glucuronosyltransferase 1 family, polypeptide A2 |
increases expression |
ISO |
Fenofibrate results in increased expression of UGT1A3 mRNA |
CTD |
PMID:17058234 |
|
NCBI chr 1:88,128,333...88,147,724
Ensembl chr 1:88,128,323...88,146,719
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G |
Ugt1a6b |
UDP glucuronosyltransferase 1 family, polypeptide A6B |
multiple interactions increases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of UGT1A6 mRNA Fenofibrate results in increased expression of UGT1A6 mRNA |
CTD |
PMID:18253720 PMID:18775883 |
|
NCBI chr 1:88,030,979...88,146,720
Ensembl chr 1:88,030,974...88,146,725
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G |
Urad |
ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5) decarboxylase |
increases expression |
ISO |
Fenofibrate results in increased expression of URAD mRNA |
CTD |
PMID:32741897 |
|
NCBI chr 5:147,251,794...147,259,250
Ensembl chr 5:147,251,794...147,259,250
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G |
Uri1 |
URI1, prefoldin-like chaperone |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of URI1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of URI1 mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr 7:37,659,417...37,722,989
Ensembl chr 7:37,659,417...37,722,976
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G |
Urm1 |
ubiquitin related modifier 1 |
decreases expression multiple interactions |
EXP |
Fenofibrate results in decreased expression of URM1 mRNA PPARA protein affects the reaction [Fenofibrate results in decreased expression of URM1 mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr 2:29,717,401...29,735,008
Ensembl chr 2:29,710,087...29,735,014
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G |
Usp1 |
ubiquitin specific peptidase 1 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of USP1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of USP1 mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr 4:98,812,047...98,823,780
Ensembl chr 4:98,812,047...98,823,780
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G |
Usp10 |
ubiquitin specific peptidase 10 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of USP10 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of USP10 mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr 8:120,637,099...120,684,299
Ensembl chr 8:120,637,099...120,684,299
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G |
Usp22 |
ubiquitin specific peptidase 22 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of USP22 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of USP22 mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr11:61,042,607...61,065,885
Ensembl chr11:61,042,611...61,065,881
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G |
Usp3 |
ubiquitin specific peptidase 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of USP3 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 9:66,421,573...66,501,996
Ensembl chr 9:66,421,919...66,500,424
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G |
Usp36 |
ubiquitin specific peptidase 36 |
decreases expression multiple interactions |
EXP |
Fenofibrate results in decreased expression of USP36 mRNA PPARA protein affects the reaction [Fenofibrate results in decreased expression of USP36 mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr11:118,150,477...118,181,086
Ensembl chr11:118,150,477...118,181,070
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G |
Usp38 |
ubiquitin specific peptidase 38 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of USP38 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of USP38 mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr 8:81,707,353...81,741,631
Ensembl chr 8:81,707,362...81,741,557
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G |
Usp4 |
ubiquitin specific peptidase 4 (proto-oncogene) |
increases expression |
ISO |
Fenofibrate results in increased expression of USP4 mRNA |
CTD |
PMID:32741897 |
|
NCBI chr 9:108,223,763...108,269,744
Ensembl chr 9:108,225,052...108,269,744
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G |
Usp7 |
ubiquitin specific peptidase 7 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of USP7 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of USP7 mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr16:8,506,586...8,574,931
Ensembl chr16:8,507,459...8,610,172
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G |
Usp9x |
ubiquitin specific peptidase 9, X chromosome |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of USP9X mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of USP9X mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr X:12,937,221...13,039,567
Ensembl chr X:12,937,737...13,039,567
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G |
Uspl1 |
ubiquitin specific peptidase like 1 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of USPL1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of USPL1 mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr 5:149,121,338...149,152,246
Ensembl chr 5:149,121,160...149,152,244
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G |
Vars1 |
valyl-tRNA synthetase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of VARS1 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr17:35,219,895...35,235,304
Ensembl chr17:35,219,963...35,235,298
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G |
Vcam1 |
vascular cell adhesion molecule 1 |
multiple interactions |
EXP ISO |
Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 mRNA] dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of VCAM1 mRNA]]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of VCAM1 mRNA] |
CTD |
PMID:20580385 PMID:21300114 |
|
NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
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G |
Vcpip1 |
valosin containing protein (p97)/p47 complex interacting protein 1 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of VCPIP1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of VCPIP1 mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr 1:9,788,847...9,818,607
Ensembl chr 1:9,788,847...9,818,607
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of VEGFA protein]] |
CTD |
PMID:31016362 |
|
NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
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G |
Vegfb |
vascular endothelial growth factor B |
increases expression |
ISO |
Fenofibrate results in increased expression of VEGFB mRNA |
CTD |
PMID:17264098 PMID:25596134 |
|
NCBI chr19:6,959,840...6,965,019
Ensembl chr19:6,959,841...6,965,019
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G |
Vnn1 |
vanin 1 |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of VNN1 mRNA |
CTD |
PMID:11798191 PMID:25572481 PMID:27665778 PMID:32741897 |
|
NCBI chr10:23,770,586...23,781,242
Ensembl chr10:23,770,586...23,781,241
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G |
Vsir |
V-set immunoregulatory receptor |
decreases expression |
ISO |
Fenofibrate results in decreased expression of VSIR mRNA |
CTD |
PMID:25572481 |
|
NCBI chr10:60,182,630...60,266,073
Ensembl chr10:60,182,630...60,208,463
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G |
Vwa8 |
von Willebrand factor A domain containing 8 |
increases expression |
ISO |
Fenofibrate results in increased expression of VWA8 mRNA |
CTD |
PMID:32741897 |
|
NCBI chr14:79,086,489...79,439,750
Ensembl chr14:79,086,492...79,439,750
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G |
Wsb1 |
WD repeat and SOCS box-containing 1 |
decreases expression multiple interactions |
EXP |
Fenofibrate results in decreased expression of WSB1 mRNA PPARA protein affects the reaction [Fenofibrate results in decreased expression of WSB1 mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr11:79,130,208...79,145,521
Ensembl chr11:79,130,198...79,145,497
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G |
Wsb2 |
WD repeat and SOCS box-containing 2 |
increases expression |
EXP |
Fenofibrate results in increased expression of WSB2 mRNA |
CTD |
PMID:21318169 |
|
NCBI chr 5:117,495,370...117,516,666
Ensembl chr 5:117,495,369...117,516,666
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G |
Wwc2 |
WW, C2 and coiled-coil domain containing 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of WWC2 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 8:48,279,117...48,443,579
Ensembl chr 8:48,276,994...48,443,959
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|
G |
Xbp1 |
X-box binding protein 1 |
affects activity decreases expression |
ISO |
Fenofibrate affects the activity of XBP1 protein Fenofibrate results in decreased expression of XBP1 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893
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|
G |
Xpc |
xeroderma pigmentosum, complementation group C |
decreases expression |
ISO |
Fenofibrate results in decreased expression of XPC mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 6:91,466,287...91,492,870
Ensembl chr 6:91,466,287...91,492,870
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G |
Xrcc5 |
X-ray repair complementing defective repair in Chinese hamster cells 5 |
multiple interactions increases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of XRCC5 mRNA Fenofibrate results in increased expression of XRCC5 mRNA |
CTD |
PMID:17264098 PMID:18253720 PMID:18775883 |
|
NCBI chr 1:72,346,576...72,434,112
Ensembl chr 1:72,346,586...72,434,111
|
|
G |
Yars1 |
tyrosyl-tRNA synthetase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of YARS1 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 4:129,083,595...129,113,033
Ensembl chr 4:129,083,553...129,113,400
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|
|
G |
Lrrc4c |
leucine rich repeat containing 4C |
multiple interactions |
ISO |
[Herbicides results in increased abundance of mesotrione] which affects the methylation of LRRC4C gene |
CTD |
PMID:34516295 |
|
NCBI chr 2:96,148,514...97,466,871
Ensembl chr 2:96,148,514...97,462,011
|
|
G |
Mfsd4b1 |
major facilitator superfamily domain containing 4B1 |
multiple interactions |
ISO |
[Herbicides results in increased abundance of mesotrione] which affects the methylation of MFSD4B gene |
CTD |
PMID:34516295 |
|
NCBI chr10:39,877,569...39,901,264
Ensembl chr10:39,877,571...39,901,264
|
|
G |
Ms4a4a |
membrane-spanning 4-domains, subfamily A, member 4A |
multiple interactions |
ISO |
[Herbicides results in increased abundance of mesotrione] which affects the methylation of MS4A4A gene |
CTD |
PMID:34516295 |
|
NCBI chr19:11,352,827...11,370,682
Ensembl chr19:11,352,887...11,370,154
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|
G |
Myo1b |
myosin IB |
multiple interactions |
ISO |
[Herbicides results in increased abundance of mesotrione] which affects the methylation of MYO1B gene |
CTD |
PMID:34516295 |
|
NCBI chr 1:51,788,915...51,955,143
Ensembl chr 1:51,788,924...51,955,230
|
|
G |
Pik3r4 |
phosphoinositide-3-kinase regulatory subunit 4 |
multiple interactions |
ISO |
[Herbicides results in increased abundance of mesotrione] which affects the methylation of PIK3R4 gene |
CTD |
PMID:34516295 |
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NCBI chr 9:105,520,156...105,564,854
Ensembl chr 9:105,520,177...105,564,856
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G |
Ppp1r2 |
protein phosphatase 1, regulatory inhibitor subunit 2 |
multiple interactions |
ISO |
[Herbicides results in increased abundance of mesotrione] which affects the methylation of PPP1R2 gene |
CTD |
PMID:34516295 |
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NCBI chr16:31,070,359...31,094,095
Ensembl chr16:31,070,355...31,094,095
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G |
Schip1 |
schwannomin interacting protein 1 |
multiple interactions |
ISO |
[Herbicides results in increased abundance of mesotrione] which affects the methylation of SCHIP1 gene |
CTD |
PMID:34516295 |
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NCBI chr 3:67,972,135...68,533,815
Ensembl chr 3:67,972,135...68,533,814
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G |
Wdr43 |
WD repeat domain 43 |
multiple interactions |
ISO |
[Herbicides results in increased abundance of mesotrione] which affects the methylation of WDR43 gene |
CTD |
PMID:34516295 |
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NCBI chr17:71,923,175...71,966,026
Ensembl chr17:71,922,890...71,966,026
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions |
EXP |
[nitisinone results in decreased activity of HPD protein] which results in decreased expression of GCLC mRNA |
CTD |
PMID:12899938 |
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NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767
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G |
Gclm |
glutamate-cysteine ligase, modifier subunit |
multiple interactions |
EXP |
[nitisinone results in decreased activity of HPD protein] which results in decreased expression of GCLM mRNA |
CTD |
PMID:12899938 |
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NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions |
EXP |
[nitisinone results in decreased activity of HPD protein] which results in decreased expression of HMOX1 mRNA |
CTD |
PMID:12899938 |
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NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
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G |
Hpd |
4-hydroxyphenylpyruvic acid dioxygenase |
multiple interactions |
EXP |
[nitisinone results in decreased activity of HPD protein] which results in decreased expression of GCLC mRNA; [nitisinone results in decreased activity of HPD protein] which results in decreased expression of GCLM mRNA; [nitisinone results in decreased activity of HPD protein] which results in decreased expression of HMOX1 mRNA; [nitisinone results in decreased activity of HPD protein] which results in decreased expression of NQO1 mRNA |
CTD |
PMID:12899938 |
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NCBI chr 5:123,309,870...123,320,786
Ensembl chr 5:123,309,870...123,320,790
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G |
Nqo1 |
NAD(P)H dehydrogenase, quinone 1 |
multiple interactions |
EXP |
[nitisinone results in decreased activity of HPD protein] which results in decreased expression of NQO1 mRNA |
CTD |
PMID:12899938 |
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NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
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