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Gene: Vsir (V-set immunoregulatory receptor) Mus musculus
Symbol: Vsir
Name: V-set immunoregulatory receptor
Description: ENCODES a protein that exhibits endopeptidase activator activity (ortholog); enzyme binding (ortholog); identical protein binding (ortholog); INVOLVED IN BMP signaling pathway; negative regulation of CD4-positive, alpha-beta T cell proliferation; negative regulation of T cell cytokine production; ASSOCIATED WITH abnormal T cell activation; hepatic necrosis; increased IgA level; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN external side of plasma membrane; plasma membrane; INTERACTS WITH 1,1-dichloroethene; 4-hydroxyphenyl retinamide; benzo[a]pyrene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4632428N05Rik; Dies1; differentiation of ESCs 1; Gi24 receptor; PD-1H; platelet receptor Gi24; V-set domain-containing immunoregulatory receptor; V-type immunoglobulin domain-containing suppressor of T-cell activation; VISTA
Homo sapiens (human) : VSIR (V-set immunoregulatory receptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Vsir (V-set immunoregulatory receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vsir (V-set immunoregulatory receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : VSIR (V-set immunoregulatory receptor)
Canis lupus familiaris (dog) : VSIR (V-set immunoregulatory receptor)
Sus scrofa (pig) : VSIR (V-set immunoregulatory receptor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381060,346,851 - 60,430,294 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371059,809,599 - 59,835,432 (+)NCBIGRCm37mm9NCBIm37
MGSCv361059,742,261 - 59,768,041 (+)NCBImm8
Celera1061,443,716 - 61,469,794 (+)NCBICelera
Cytogenetic Map10 B4NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Vsir
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1614298
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2019-10-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.