Akr1b10 (aldo-keto reductase family 1, member B10) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Akr1b10 (aldo-keto reductase family 1, member B10) Mus musculus
Analyze
Symbol: Akr1b10
Name: aldo-keto reductase family 1, member B10
RGD ID: 1317960
MGI Page MGI
Description: Predicted to enable geranylgeranyl reductase activity; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; and retinal dehydrogenase activity. Located in mitochondrion. Is expressed in adrenal gland. Orthologous to several human genes including AKR1B10 (aldo-keto reductase family 1 member B10).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2310005E10Rik; Akr1b16; aldo-keto reductase family 1, member B10 (aldose reductase)
RGD Orthologs
Human
Rat
Bonobo
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm15806  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39634,361,182 - 34,373,884 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl634,361,153 - 34,373,885 (+)EnsemblGRCm39 Ensembl
GRCm38634,384,247 - 34,396,949 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl634,384,218 - 34,396,950 (+)EnsemblGRCm38mm10GRCm38
MGSCv37634,334,247 - 34,346,949 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36634,314,405 - 34,327,107 (+)NCBIMGSCv36mm8
Celera634,380,662 - 34,393,359 (+)NCBICelera
Cytogenetic Map6B1NCBI
cM Map614.93NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid  (ISO)
(E)-cinnamyl alcohol  (ISO)
(E,E)-2,4-hexadienal  (ISO)
(R)-acetoin  (ISO)
1,2-dimethylhydrazine  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
13-dihydrodaunorubicin  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-(chloromethyl)pyridine  (ISO)
2-acetamidofluorene  (ISO)
2-hexenal  (ISO)
2-hydroxypropanoic acid  (ISO)
2-palmitoylglycerol  (ISO)
2-tert-butylhydroquinone  (ISO)
3-chloropropane-1,2-diol  (ISO)
3-Hydroxybenzo[a]pyrene  (ISO)
3-methyl-3H-imidazo[4,5-f]quinolin-2-amine  (ISO)
3-phenylprop-2-enal  (ISO)
4,4'-methylene-bis-(2-chloroaniline)  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroperoxycyclophosphamide  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (EXP)
4-methylpentanal  (ISO)
4-nitro-1,2-phenylenediamine  (ISO)
5-fluorouracil  (ISO)
7,12-dimethyltetraphene  (ISO)
9,10-phenanthroquinone  (ISO)
9-cis-retinal  (ISO)
[6]-Shogaol  (ISO)
acetoin  (ISO)
acrolein  (ISO)
actinomycin D  (ISO)
adhumulone  (ISO)
aflatoxin B1  (ISO)
all-trans-4-oxoretinal  (ISO)
all-trans-dehydroretinal  (ISO)
all-trans-retinal  (ISO)
all-trans-retinol  (ISO)
Aloe emodin  (ISO)
alpha-hexylcinnamaldehyde  (ISO)
amoxicillin  (ISO)
ampicillin  (ISO)
anthranilic acid  (ISO)
antimonite  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
Augmentin  (ISO)
azathioprine  (ISO)
Bandrowski's base  (ISO)
benzalkonium chloride  (ISO)
benzidine  (ISO)
benzo[a]pyrene  (EXP,ISO)
Benzo[a]pyrene-7,8-diol  (ISO)
benzo[a]pyrene-7,8-dione  (ISO)
benzoic acid  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bortezomib  (ISO)
butane-2,3-diol  (ISO)
butane-2,3-dione  (ISO)
cadmium atom  (ISO)
cadmium sulfate  (ISO)
captan  (EXP)
carbamazepine  (ISO)
carbon nanotube  (EXP)
chlorambucil  (ISO)
chromium(6+)  (ISO)
chrysin  (ISO)
cinnamyl alcohol  (ISO)
ciprofibrate  (ISO)
cisplatin  (ISO)
clavulanic acid  (ISO)
Clofop  (ISO)
cobalt dichloride  (ISO)
Cohumulone  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
crotonaldehyde  (ISO)
cyclosporin A  (ISO)
D-glyceraldehyde  (ISO)
daunorubicin  (ISO)
DDT  (ISO)
diarsenic trioxide  (ISO)
dibenzo[a,l]pyrene  (ISO)
diethyl maleate  (ISO)
diethylstilbestrol  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
diquat  (ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
emodin  (ISO)
ethanol  (EXP)
ethoxyquin  (ISO)
Ethyl 1-benzyl-3-hydroxy- 2-oxo[5H]pyrrole-4-carboxylate  (ISO)
Ethyl acrylate  (ISO)
eugenol  (ISO)
farnesal  (ISO)
farnesol  (ISO)
fenofibrate  (ISO)
Fidarestat  (ISO)
flucloxacillin  (ISO)
folpet  (EXP)
formaldehyde  (ISO)
formononetin  (ISO)
Frangulin A  (ISO)
Frangulin B  (ISO)
furan  (ISO)
gemfibrozil  (ISO)
gentamycin  (ISO)
geranylgeraniol  (ISO)
glyceraldehyde  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
hexane  (ISO)
hexane-2,3-dione  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
indan-1-ol  (ISO)
indometacin  (ISO)
isoeugenol  (ISO)
isoniazide  (ISO)
Isoxanthohumol  (ISO)
L-ascorbic acid  (ISO)
lead diacetate  (ISO)
lead(II) chloride  (ISO)
Licochalcone B  (ISO)
lipopolysaccharide  (ISO)
LY294002  (ISO)
menadione  (ISO)
methyl salicylate  (ISO)
methylisothiazolinone  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-N-nitrosourea  (EXP)
N-nitrosodiethylamine  (ISO)
N-Nitrosopyrrolidine  (ISO)
NADP zwitterion  (ISO)
NADP(+)  (ISO)
naphthalenes  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
nitrososulfamethoxazole  (ISO)
Nutlin-3  (ISO)
O-methyleugenol  (ISO)
ochratoxin A  (ISO)
oleanolic acid  (ISO)
p-chloromercuribenzenesulfonic acid  (ISO)
para-Cresidine  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
pazopanib  (ISO)
pentane-2,3-dione  (ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenethyl caffeate  (ISO)
phenobarbital  (ISO)
phenol  (ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
picoxystrobin  (ISO)
pimecrolimus  (ISO)
pirinixic acid  (EXP,ISO)
potassium bromate  (EXP)
progesterone  (ISO)
propan-2-ol  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
quinolin-8-ol  (ISO)
rac-lactic acid  (ISO)
reserpine  (ISO)
resorcinol  (ISO)
resveratrol  (EXP)
rifampicin  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium dodecyl sulfate  (ISO)
sorbinil  (ISO)
sulforaphane  (ISO)
sulindac  (ISO)
sulindac sulfone  (ISO)
tebuconazole  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
tetraphene  (ISO)
thioacetamide  (ISO)
titanium dioxide  (ISO)
trans-isoeugenol  (ISO)
Tributyltin oxide  (ISO)
trichloroethene  (ISO)
Triptolide  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IBA,ISO)
extracellular region  (ISO)
lysosome  (ISO)
mitochondrion  (HDA,IBA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Properties and tissue distribution of a novel aldo-keto reductase encoding in a rat gene (Akr1b10). Endo S, etal., Arch Biochem Biophys. 2010 Nov 15;503(2):230-7. Epub 2010 Aug 13.
2. Aldo-keto reductases and bioactivation/detoxication. Jin Y and Penning TM, Annu Rev Pharmacol Toxicol. 2007;47:263-92.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. Meta-analysis of three diabetes population studies: association of inactive ALDH2 genotype with maternal inheritance of diabetes. Murata C, etal., Diabetes Res Clin Pract. 2004 Dec;66 Suppl 1:S145-7.
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. ALDH2/ADH2 polymorphism associated with vasculopathy and neuropathy in type 2 diabetes. Suzuki Y, etal., Alcohol Clin Exp Res. 2004 Aug;28(8 Suppl Proceedings):111S-116S.
9. Aldehyde dehydrogenase 2 genotype in type 1 diabetes mellitus. Suzuki Y, etal., Diabetes Res Clin Pract. 2003 May;60(2):139-41.
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:16141072   PMID:16141073   PMID:18614015   PMID:21267068   PMID:21276782   PMID:21677750   PMID:21873635   PMID:23689354  
PMID:28322781   PMID:34954342   PMID:37142655  


Genomics

Comparative Map Data
Akr1b10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39634,361,182 - 34,373,884 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl634,361,153 - 34,373,885 (+)EnsemblGRCm39 Ensembl
GRCm38634,384,247 - 34,396,949 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl634,384,218 - 34,396,950 (+)EnsemblGRCm38mm10GRCm38
MGSCv37634,334,247 - 34,346,949 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36634,314,405 - 34,327,107 (+)NCBIMGSCv36mm8
Celera634,380,662 - 34,393,359 (+)NCBICelera
Cytogenetic Map6B1NCBI
cM Map614.93NCBI
AKR1B10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387134,527,567 - 134,541,412 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7134,527,567 - 134,541,412 (+)EnsemblGRCh38hg38GRCh38
GRCh377134,212,319 - 134,226,164 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367133,862,939 - 133,876,700 (+)NCBINCBI36Build 36hg18NCBI36
Build 347133,669,653 - 133,683,413NCBI
Celera7128,949,765 - 128,963,585 (+)NCBICelera
Cytogenetic Map7q33NCBI
HuRef7128,514,188 - 128,528,007 (+)NCBIHuRef
CHM1_17134,146,625 - 134,160,442 (+)NCBICHM1_1
T2T-CHM13v2.07135,835,650 - 135,849,492 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27133,556,663 - 133,570,483 (+)NCBI
Akr1b10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8464,005,632 - 64,027,860 (+)NCBIGRCr8
mRatBN7.2463,038,459 - 63,060,336 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl463,040,169 - 63,053,852 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx467,989,273 - 68,004,664 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0463,904,967 - 63,920,356 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0462,307,393 - 62,322,778 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0461,813,265 - 61,830,371 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl461,771,970 - 61,828,657 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0461,550,785 - 61,568,072 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4461,755,871 - 61,771,264 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1462,032,000 - 62,047,393 (+)NCBI
Celera458,091,866 - 58,107,253 (+)NCBICelera
Cytogenetic Map4q22NCBI
AKR1B10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26171,343,443 - 171,357,364 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1723,353,774 - 23,367,619 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07126,486,012 - 126,499,852 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17138,992,802 - 139,006,042 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7138,992,835 - 139,006,003 (+)Ensemblpanpan1.1panPan2

Variants

.
Variants in Akr1b10
460 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:628
Count of miRNA genes:399
Interacting mature miRNAs:442
Transcripts:ENSMUST00000038383, ENSMUST00000115051, ENSMUST00000139156, ENSMUST00000144072, ENSMUST00000144384, ENSMUST00000182055
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396633110Mouse
4140989Spqq2_msperm quality QTL 2 (mouse)Not determined1771159851711719Mouse
26884441Sklq3_mskull length QTL 3, 5 week (mouse)6760000080576983Mouse
1357520Axtq2_manxiety QTL 2 (mouse)Not determined6450382348703611Mouse
10043869Cia6a_mcollagen induced arthritis QTL 6a (mouse)Not determined61211797146118069Mouse
11252142Mom12_mModifier of Min 12 (mouse)63387226167872400Mouse
1301850Fglu_mfasting glucose (mouse)Not determined61771159851711719Mouse
4141749Obrq2_mobesity resistance QTL 2 (mouse)Not determined1275122146751333Mouse
1300959Lxw2_mlupus BXSB x NZW 2 (mouse)Not determined63387226167872400Mouse
1301724Pcd4ts1_mp-glycoprotein positive CD4 T cell subset 1 (mouse)Not determined61771159851711719Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396633110Mouse
10412107Desp4_mdespair 4 (mouse)Not determined62004983054049830Mouse
1357442Dbts1_mdiabetes 1 (mouse)Not determined61823414773364675Mouse
4141988Obrq3_mobesity resistance QTL 3 (mouse)Not determined2829099362291115Mouse
11353841Bmiq3_mbody mass index QTL 3 (mouse)6450382348703611Mouse
11353840Bmiq2_mbody mass index QTL 2 (mouse)6450382345291115Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487403016Mouse
11352717Obrq2a_mobesity resistance QTL 2a (mouse)63169434134847895Mouse
25440480Moaq2_mmodifier of alien QTL 2 (mouse)63050001117476961Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396633110Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396633110Mouse
1300731Smdq3_msegregation of mitochondrial DNA QTL 3 (mouse)Not determined6424920638249325Mouse
12904940Edlmmq5_mextensor digitorum longus muscle mass QTL 5 (mouse)61961634653616346Mouse
15039372Nmrs22_mNAFLD-associated magnetic resonance shift 22 (mouse)6147633435476334Mouse
4141782Mrdq5_mmodifier of retinal degeneration QTL 5 (mouse)Not determined3282758578215957Mouse
12904943Tammq4_mtibialis anterior muscle mass QTL 4 (mouse)61961634653616346Mouse
10412213Sxbq2_mSGC/Knj cross B6 QTL 2 (mouse)Not determined61991268571299759Mouse
12880425V25Dq5_mvitamin D inactive form serum level QTL 5 (mouse)63267698066676980Mouse
1302051Sluc7_msusceptibility to lung cancer 7 (mouse)Not determined6929707443297168Mouse
4141454Obrq4_mobesity resistance QTL 4 (mouse)Not determined3170349965703611Mouse
14700690Ccs6_mcolon cancer susceptibility 6 (mouse)62377693457776934Mouse
27226726Tibmd7_mtibia midshaft diameter 7, 16 week (mouse)61769999953476985Mouse
12904952Gmmq4_mgastrocnemius muscle mass QTL 4 (mouse)61961634653616346Mouse
1357481Aaj2_manxiety in A/J 2 (mouse)Not determined6450382348703611Mouse
1301998Bts2_mbladder tumor susceptibility 2 (mouse)Not determined61275122146751333Mouse
13208564Bmiq7_mbody mass index QTL 7 (mouse)62499999979976983Mouse


Sequence


Ensembl Acc Id: ENSMUST00000038383   ⟹   ENSMUSP00000039114
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl634,361,153 - 34,373,885 (+)Ensembl
GRCm38.p6 Ensembl634,384,218 - 34,396,950 (+)Ensembl
Ensembl Acc Id: ENSMUST00000115051   ⟹   ENSMUSP00000110703
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl634,361,216 - 34,373,683 (+)Ensembl
GRCm38.p6 Ensembl634,384,281 - 34,396,748 (+)Ensembl
Ensembl Acc Id: ENSMUST00000139156   ⟹   ENSMUSP00000138639
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl634,361,216 - 34,373,882 (+)Ensembl
GRCm38.p6 Ensembl634,384,281 - 34,396,947 (+)Ensembl
Ensembl Acc Id: ENSMUST00000144072
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl634,368,366 - 34,369,890 (+)Ensembl
GRCm38.p6 Ensembl634,391,431 - 34,392,955 (+)Ensembl
Ensembl Acc Id: ENSMUST00000144384
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl634,361,184 - 34,366,514 (+)Ensembl
GRCm38.p6 Ensembl634,384,249 - 34,389,579 (+)Ensembl
Ensembl Acc Id: ENSMUST00000182055
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl634,366,534 - 34,367,502 (+)Ensembl
GRCm38.p6 Ensembl634,389,599 - 34,390,567 (+)Ensembl
RefSeq Acc Id: NM_172398   ⟹   NP_765986
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39634,361,182 - 34,373,884 (+)NCBI
GRCm38634,384,247 - 34,396,949 (+)NCBI
MGSCv37634,334,247 - 34,346,949 (+)RGD
Celera634,380,662 - 34,393,359 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_149754
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39634,361,182 - 34,373,884 (+)NCBI
GRCm38634,384,247 - 34,396,949 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_765986 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH26843 (Get FASTA)   NCBI Sequence Viewer  
  BAC38615 (Get FASTA)   NCBI Sequence Viewer  
  EDL13691 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000039114
  ENSMUSP00000039114.8
  ENSMUSP00000110703.2
  ENSMUSP00000138639.2
RefSeq Acc Id: NP_765986   ⟸   NM_172398
- UniProtKB: G5E895 (UniProtKB/TrEMBL),   Q8BIV6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000138639   ⟸   ENSMUST00000139156
Ensembl Acc Id: ENSMUSP00000110703   ⟸   ENSMUST00000115051
Ensembl Acc Id: ENSMUSP00000039114   ⟸   ENSMUST00000038383
Protein Domains
NADP-dependent oxidoreductase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G5E895-F1-model_v2 AlphaFold G5E895 1-316 view protein structure

Promoters
RGD ID:6838725
Promoter ID:MM_KWN:45527
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000115051,   OTTMUST00000035094,   UC009BHA.1,   UC009BHC.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36634,334,014 - 34,334,514 (+)MPROMDB
RGD ID:6889286
Promoter ID:EPDNEW_M8094
Type:initiation region
Name:Akr1b10_1
Description:Mus musculus aldo-keto reductase family 1, member B10 , transcriptvariant 2, non-coding RNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38634,384,236 - 34,384,296EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1915111 AgrOrtholog
Ensembl Genes ENSMUSG00000061758 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000038383 ENTREZGENE
  ENSMUST00000038383.14 UniProtKB/TrEMBL
  ENSMUST00000115051.8 UniProtKB/TrEMBL
  ENSMUST00000139156 ENTREZGENE
  ENSMUST00000139156.8 UniProtKB/TrEMBL
Gene3D-CATH 3.20.20.100 UniProtKB/TrEMBL
InterPro Aldo/ket_reductase_CS UniProtKB/TrEMBL
  Aldo/keto_reductase_subgr UniProtKB/TrEMBL
  NADP_OxRdtase_dom UniProtKB/TrEMBL
  NADP_OxRdtase_dom_sf UniProtKB/TrEMBL
KEGG Report mmu:67861 UniProtKB/TrEMBL
MGD MGI:1915111 ENTREZGENE
NCBI Gene 67861 ENTREZGENE
PANTHER ALDO-KETO REDUCTASE FAMILY 1 MEMBER B10 UniProtKB/TrEMBL
  ALDO/KETO REDUCTASE UniProtKB/TrEMBL
Pfam Aldo_ket_red UniProtKB/TrEMBL
PhenoGen Akr1b10 PhenoGen
PIRSF AKR UniProtKB/TrEMBL
PRINTS ALDKETRDTASE UniProtKB/TrEMBL
PROSITE ALDOKETO_REDUCTASE_1 UniProtKB/TrEMBL
  ALDOKETO_REDUCTASE_2 UniProtKB/TrEMBL
  ALDOKETO_REDUCTASE_3 UniProtKB/TrEMBL
Superfamily-SCOP Aldo/ket_red UniProtKB/TrEMBL
UniProt D3Z494_MOUSE UniProtKB/TrEMBL
  G5E895 ENTREZGENE, UniProtKB/TrEMBL
  Q8BIV6 ENTREZGENE, UniProtKB/TrEMBL
  Q8R318_MOUSE UniProtKB/TrEMBL
  S4R2G9_MOUSE UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-07-04 Akr1b10  aldo-keto reductase family 1, member B10  Akr1b10  aldo-keto reductase family 1, member B10 (aldose reductase)  Symbol and/or name change 5135510 APPROVED