Nat8f3 (N-acetyltransferase 8 (GCN5-related) family member 3) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References FTP Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Nat8f3 (N-acetyltransferase 8 (GCN5-related) family member 3) Mus musculus
Analyze
Symbol: Nat8f3
Name: N-acetyltransferase 8 (GCN5-related) family member 3
RGD ID: 732676
MGI Page MGI
Description: Exhibits H4 histone acetyltransferase activity. Involved in histone acetylation. Localizes to nuclear membrane. Orthologous to human NAT8 (N-acetyltransferase 8 (putative)); INTERACTS WITH benzo[a]pyrene; genistein; tetrachloroethene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4833414A14Rik; 4930583K21Rik; camello-like 3; camello-like protein 3; Cml; cml3; N-acetyltransferase CML3; N-acetyltransferase family 8 member 3; probable N-acetyltransferase CML3
RGD Orthologs
Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39685,737,613 - 85,742,726 (-)NCBIGRCm39mm39
GRCm38685,760,631 - 85,765,767 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl685,732,513 - 85,765,754 (-)EnsemblGRCm38mm10GRCm38
MGSCv37685,710,625 - 85,715,738 (-)NCBIGRCm37mm9NCBIm37
MGSCv36685,726,307 - 85,731,402 (-)NCBImm8
MGSCv36686,666,142 - 86,695,068 (-)NCBImm8
Celera687,754,957 - 87,774,445 (-)NCBICelera
Cytogenetic Map6C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:3510743   PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:16141072   PMID:16141073   PMID:20059953   PMID:21267068   PMID:21873635   PMID:25123547  


Genomics

Comparative Map Data
Nat8f3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39685,737,613 - 85,742,726 (-)NCBIGRCm39mm39
GRCm38685,760,631 - 85,765,767 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl685,732,513 - 85,765,754 (-)EnsemblGRCm38mm10GRCm38
MGSCv37685,710,625 - 85,715,738 (-)NCBIGRCm37mm9NCBIm37
MGSCv36685,726,307 - 85,731,402 (-)NCBImm8
MGSCv36686,666,142 - 86,695,068 (-)NCBImm8
Celera687,754,957 - 87,774,445 (-)NCBICelera
Cytogenetic Map6C3NCBI
Nat8f3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24118,241,792 - 118,246,010 (-)NCBI
Rnor_6.0 Ensembl4117,490,035 - 117,490,721 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04117,488,089 - 117,492,315 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04182,065,274 - 182,068,214 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44119,964,411 - 119,966,307 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14120,208,893 - 120,209,809 (-)NCBI
Celera4107,222,119 - 107,226,343 (-)NCBICelera
Cytogenetic Map4q34NCBI

Position Markers
UniSTS:235483  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38685,830,393 - 85,830,633UniSTSGRCm38
MGSCv37685,780,387 - 85,780,627UniSTSGRCm37
Celera687,767,880 - 87,768,120UniSTS
Cytogenetic Map6C3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487426034Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63866962592607450Mouse
1300618Pgia19_mproteoglycan induced arthritis 19 (mouse)Not determined64531405987426034Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
4141028Mclr_mmethylcholanthrene lymphoma resistance (mouse)Not determined5437342788379171Mouse
15039373Adip28_madiposity 28 (mouse)65630821190308211Mouse
15039375Bw41_mbody weight QTL 41 (mouse)65630821190308211Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65844758392447710Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65854043392540433Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66005768094057799Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66348473897484905Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666713869100714031Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670425898104426034Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670425898104426034Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670425898104426034Mouse
4141990Etax6_methanol induced ataxia 6 (mouse)Not determined7132262186275719Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67132262193464093Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671575060105575178Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671981024105981170Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671981024105981170Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673500000134700000Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675447583104503555Mouse
1301571Arrd1_mage-related retinal degeneration 1 (mouse)Not determined67554435692607450Mouse
1300674Nidd3n_mnon-insulin-dependent diabetes mellitus 3 in NSY (mouse)Not determined67554435694225955Mouse
10412195Efw_mepididymal fat weight (mouse)Not determined67554435694225955Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675607306109607450Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675716503109716697Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676463949110464093Mouse
14697704Stsl4_mSalmonella typhimurium susceptibility locus 4 (mouse)67710000090000000Mouse
13824985Alh1_mamplitude of lateral head displacement 1 (mouse)67800000097000000Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678629504121115387Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681500000102200000Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683713869147052561Mouse
11251720Ewc4_methanol withdrawal and consumption 4 (mouse)684122513118122513Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:289
Count of miRNA genes:138
Interacting mature miRNAs:143
Transcripts:ENSMUST00000050780, ENSMUST00000168531
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000050780   ⟹   ENSMUSP00000093431
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl685,760,649 - 85,765,744 (-)Ensembl
RefSeq Acc Id: ENSMUST00000168531   ⟹   ENSMUSP00000131413
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl685,760,679 - 85,762,480 (-)Ensembl
RefSeq Acc Id: ENSMUST00000201219
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl685,732,513 - 85,765,754 (-)Ensembl
RefSeq Acc Id: NM_001037842   ⟹   NP_001032931
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39685,737,613 - 85,742,726 (-)NCBI
GRCm38685,760,631 - 85,765,744 (-)NCBI
MGSCv37685,710,625 - 85,715,738 (-)RGD
Celera687,754,957 - 87,774,445 (-)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_017321841   ⟹   XP_017177330
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39685,737,613 - 85,739,636 (-)NCBI
GRCm38685,760,631 - 85,762,654 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001032931 (Get FASTA)   NCBI Sequence Viewer  
  XP_017177330 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH14696 (Get FASTA)   NCBI Sequence Viewer  
  BAC32679 (Get FASTA)   NCBI Sequence Viewer  
  Q9JIY8 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001032931   ⟸   NM_001037842
- UniProtKB: Q9JIY8 (UniProtKB/Swiss-Prot),   A0A0R4J157 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017177330   ⟸   XM_017321841
- Peptide Label: isoform X1
- UniProtKB: Q9JIY8 (UniProtKB/Swiss-Prot),   A0A0R4J157 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000131413   ⟸   ENSMUST00000168531
RefSeq Acc Id: ENSMUSP00000093431   ⟸   ENSMUST00000050780
Protein Domains
N-acetyltransferase

Promoters
RGD ID:6890240
Promoter ID:EPDNEW_M8571
Type:single initiation site
Name:Nat8f3_1
Description:Mus musculus N-acetyltransferase 8 (GCN5-related) family member3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38685,765,753 - 85,765,813EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2136449 AgrOrtholog
Ensembl Genes ENSMUSG00000051262 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSG00000079495 UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000084938 UniProtKB/Swiss-Prot
  ENSMUSP00000093431 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000131413 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000133846 UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000050780 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000087656 UniProtKB/Swiss-Prot
  ENSMUST00000168531 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000174143 UniProtKB/Swiss-Prot
InterPro Acyl_CoA_acyltransferase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GNAT_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:100504710 UniProtKB/Swiss-Prot
  mmu:93674 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:2136449 ENTREZGENE
NCBI Gene 93674 ENTREZGENE
Pfam Acetyltransf_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nat8f3 PhenoGen
PROSITE GNAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF55729 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J157 ENTREZGENE, UniProtKB/TrEMBL
  NT8F3_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q8BQW2 UniProtKB/Swiss-Prot
  Q91WM7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-02 Nat8f3  N-acetyltransferase 8 (GCN5-related) family member 3  Cml3  camello-like 3  Symbol and/or name change 5135510 APPROVED