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Gene: Klf11 (Kruppel-like factor 11) Mus musculus
Symbol: Klf11
Name: Kruppel-like factor 11
Description: Exhibits DNA-binding transcription factor activity. Involved in negative regulation of transcription, DNA-templated. Predicted to localize to the cytosol; focal adhesion; and nuclear body. Human ortholog(s) of this gene implicated in maturity-onset diabetes of the young type 7 and type 2 diabetes mellitus. Is expressed in several structures, including brain; early conceptus; genitourinary system; liver; and sensory organ. Orthologous to human KLF11 (Kruppel like factor 11); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9830142A17; D12Ertd427e; Krueppel-like factor 11; TGFB inducible early growth response 2; TGFB inducible early growth response 3; TGFB-inducible early growth response protein 2b; TGFB-inducible early growth response protein 3; TIEG-3; Tieg2; Tieg2b; Tieg3; transforming growth factor-beta-inducible early growth response protein 3
Homo sapiens (human) : KLF11 (Kruppel like factor 11)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Klf11 (Kruppel-like factor 11)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Klf11 (Kruppel like factor 11)
Pan paniscus (bonobo/pygmy chimpanzee) : KLF11 (Kruppel like factor 11)
Canis lupus familiaris (dog) : KLF11 (Kruppel like factor 11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Klf11 (Kruppel like factor 11)
Sus scrofa (pig) : KLF11 (Kruppel like factor 11)
Chlorocebus sabaeus (African green monkey) : KLF11 (Kruppel like factor 11)
Heterocephalus glaber (naked mole-rat) : Klf11 (Kruppel like factor 11)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1224,651,274 - 24,662,789 (+)Ensembl
GRCm381224,651,371 - 24,662,782 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371225,336,236 - 25,347,647 (+)NCBIGRCm37mm9NCBIm37
MGSCv361225,240,353 - 25,251,754 (+)NCBImm8
Celera1226,112,243 - 26,123,694 (+)NCBICelera
Cytogenetic Map12 A1.3NCBI
cM Map128.49NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Klf11
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1616592
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2020-01-21
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.