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Gene: Klf11 (Kruppel-like factor 11) Mus musculus
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Symbol: Klf11
Name: Kruppel-like factor 11
Description: Exhibits DNA-binding transcription factor activity. Involved in negative regulation of transcription, DNA-templated. Predicted to localize to the cytosol; focal adhesion; and nuclear body. Human ortholog(s) of this gene implicated in maturity-onset diabetes of the young type 7 and type 2 diabetes mellitus. Is expressed in several structures, including brain; early conceptus; genitourinary system; liver; and sensory organ. Orthologous to human KLF11 (Kruppel like factor 11); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9830142A17; D12Ertd427e; Krueppel-like factor 11; TGFB inducible early growth response 2; TGFB inducible early growth response 3; TGFB-inducible early growth response protein 2b; TGFB-inducible early growth response protein 3; TIEG-3; Tieg2; Tieg2b; Tieg3; transforming growth factor-beta-inducible early growth response protein 3
Orthologs:
Homo sapiens (human) : KLF11 (Kruppel like factor 11)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Klf11 (Kruppel-like factor 11)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Klf11 (Kruppel like factor 11)
Pan paniscus (bonobo/pygmy chimpanzee) : KLF11 (Kruppel like factor 11)
Canis lupus familiaris (dog) : KLF11 (Kruppel like factor 11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Klf11 (Kruppel like factor 11)
Sus scrofa (pig) : KLF11 (Kruppel like factor 11)
Chlorocebus sabaeus (African green monkey) : KLF11 (Kruppel like factor 11)
Heterocephalus glaber (naked mole-rat) : Klf11 (Kruppel like factor 11)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1224,651,274 - 24,662,789 (+)Ensembl
GRCm381224,651,371 - 24,662,782 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371225,336,236 - 25,347,647 (+)NCBIGRCm37mm9NCBIm37
MGSCv361225,240,353 - 25,251,754 (+)NCBImm8
Celera1226,112,243 - 26,123,694 (+)NCBICelera
Cytogenetic Map12 A1.3NCBI
cM Map128.49NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Klf11
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1616592
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2020-01-21
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.