Hectd1 (HECT domain E3 ubiquitin protein ligase 1) - Rat Genome Database

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Gene: Hectd1 (HECT domain E3 ubiquitin protein ligase 1) Mus musculus
Analyze
Symbol: Hectd1
Name: HECT domain E3 ubiquitin protein ligase 1
RGD ID: 1557564
MGI Page MGI
Description: Enables ubiquitin protein ligase activity. Acts upstream of or within several processes, including chordate embryonic development; circulatory system development; and protein ubiquitination. Predicted to be active in nuclear speck. Is expressed in several structures, including extraembryonic component; genitourinary system; heart; hemolymphoid system gland; and lung. Orthologous to human HECTD1 (HECT domain E3 ubiquitin protein ligase 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A630086P08Rik; AI844876; b2b327C; b2b327Clo; E3 ubiquitin-protein ligase HECTD1; HECT domain containing 1; HECT domain-containing protein 1; HECT-type E3 ubiquitin transferase HECTD1; MGC12070; o; opm; protein open mind
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391251,790,504 - 51,876,540 (-)NCBIGRCm39mm39
GRCm39 Ensembl1251,790,505 - 51,876,319 (-)Ensembl
GRCm381251,743,721 - 51,829,757 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1251,743,722 - 51,829,536 (-)EnsemblGRCm38mm10GRCm38
MGSCv371252,844,709 - 52,930,523 (-)NCBIGRCm37mm9NCBIm37
MGSCv361252,665,339 - 52,750,973 (-)NCBImm8
Celera1253,048,069 - 53,133,676 (-)NCBICelera
Cytogenetic Map12B3NCBI
cM Map1222.11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3. Mouse MP Annotation Import Pipeline RGD automated import pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:8889548   PMID:9636176   PMID:10349636   PMID:10512203   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12520002   PMID:14610273   PMID:15368895   PMID:15755804  
PMID:15782199   PMID:15840001   PMID:16141072   PMID:16141073   PMID:16602821   PMID:17442300   PMID:17967808   PMID:18799693   PMID:21267068   PMID:21873635   PMID:22431752   PMID:24855001  
PMID:25807483   PMID:26296893   PMID:26907377   PMID:27626380   PMID:28073378   PMID:28190767   PMID:29306077   PMID:29540674   PMID:30333137   PMID:30578278   PMID:31299141   PMID:31301385  
PMID:32325033   PMID:32555320   PMID:33148417   PMID:33711283   PMID:33853758   PMID:35148069  


Genomics

Comparative Map Data
Hectd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391251,790,504 - 51,876,540 (-)NCBIGRCm39mm39
GRCm39 Ensembl1251,790,505 - 51,876,319 (-)Ensembl
GRCm381251,743,721 - 51,829,757 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1251,743,722 - 51,829,536 (-)EnsemblGRCm38mm10GRCm38
MGSCv371252,844,709 - 52,930,523 (-)NCBIGRCm37mm9NCBIm37
MGSCv361252,665,339 - 52,750,973 (-)NCBImm8
Celera1253,048,069 - 53,133,676 (-)NCBICelera
Cytogenetic Map12B3NCBI
cM Map1222.11NCBI
HECTD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381431,100,117 - 31,207,793 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1431,100,117 - 31,207,804 (-)EnsemblGRCh38hg38GRCh38
GRCh371431,569,323 - 31,676,999 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361430,639,075 - 30,746,440 (-)NCBINCBI36hg18NCBI36
Build 341430,639,074 - 30,746,274NCBI
Celera1411,434,814 - 11,542,175 (-)NCBI
Cytogenetic Map14q12NCBI
HuRef1411,686,880 - 11,794,092 (-)NCBIHuRef
CHM1_11431,568,490 - 31,675,834 (-)NCBICHM1_1
T2T-CHM13v2.01425,297,934 - 25,405,631 (-)NCBI
Hectd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2669,181,429 - 69,267,803 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl669,181,436 - 69,268,053 (-)Ensembl
Rnor_6.0672,509,658 - 72,596,285 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl672,510,255 - 72,596,446 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0682,073,583 - 82,157,571 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4671,842,842 - 71,930,042 (-)NCBIRGSC3.4rn4RGSC3.4
Celera668,057,228 - 68,144,745 (-)NCBICelera
Cytogenetic Map6q23NCBI
Hectd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540929,373,572 - 29,470,623 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540929,373,572 - 29,470,623 (+)NCBIChiLan1.0ChiLan1.0
HECTD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11430,070,567 - 30,176,915 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1430,070,567 - 30,176,915 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01411,871,973 - 11,979,548 (-)NCBIMhudiblu_PPA_v0panPan3
HECTD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1810,399,183 - 10,493,074 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl810,400,604 - 10,491,247 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha810,325,552 - 10,419,807 (-)NCBI
ROS_Cfam_1.0810,500,312 - 10,594,712 (-)NCBI
ROS_Cfam_1.0 Ensembl810,500,682 - 10,594,730 (-)Ensembl
UMICH_Zoey_3.1810,183,683 - 10,277,214 (-)NCBI
UNSW_CanFamBas_1.0810,260,046 - 10,354,820 (-)NCBI
UU_Cfam_GSD_1.0810,544,896 - 10,638,539 (-)NCBI
Hectd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864042,255,912 - 42,347,810 (-)NCBI
SpeTri2.0NW_0049364945,761,801 - 5,853,673 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HECTD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl768,318,417 - 68,422,396 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1768,318,167 - 68,422,403 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2773,199,984 - 73,303,548 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Hectd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248201,097,463 - 1,196,499 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248201,097,323 - 1,196,556 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
UniSTS:236841  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381251,783,455 - 51,783,775UniSTSGRCm38
MGSCv371252,884,442 - 52,884,762UniSTSGRCm37
Celera1253,087,738 - 53,088,058UniSTS
Cytogenetic Map12C1UniSTS
cM Map1217.0UniSTS
AI844876  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381251,798,750 - 51,798,896UniSTSGRCm38
MGSCv371252,899,737 - 52,899,883UniSTSGRCm37
Celera1253,102,943 - 53,103,089UniSTS
Cytogenetic Map12C1UniSTS
cM Map1217.0UniSTS
Whitehead/MRC_RH12449.54UniSTS


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142234Tmc1m3_mTmc1 modifier 3 (mouse)Not determined12541844077031203Mouse
27226753Femd7_mfemur midshaft diameter 7, 10 week (mouse)12955000084146774Mouse
13207568Tcq14_mtotal cholesterol QTL 14 (mouse)121166000197176774Mouse
13524839Ppiq10_mprepulse inhibition QTL 10 (mouse)121304319554945798Mouse
1558978Cplaq10_mcircadian period of locomotor activity 10 (mouse)Not determined121534102679040364Mouse
1301574Lmblgq5_mlimb length QTL 5 (mouse)Not determined121759644780956883Mouse
15039339Nmrs29_mNAFLD-associated magnetic resonance shift 29 (mouse)121782585251825852Mouse
10043848Hdlq90_mHDL QTL 90 (mouse)Not determined121783993951840081Mouse
1300870Ath18_matherosclerosis 18 (mouse)Not determined121825996652260067Mouse
12904956Edlmmq10_mextensor digitorum longus muscle mass QTL 10 (mouse)121973983353739833Mouse
1302172Skts5_mskin tumor susceptibility 5 (mouse)Not determined122214886656149016Mouse
1301989Hdlq18_mHDL QTL 18 (mouse)Not determined122916068563160884Mouse
1300636Gct2_mgranulosa cell tumorigenesis 2 (mouse)Not determined122916068563160884Mouse
4141843Moen3_mmodifier of engrailed QTL 3 (mouse)Not determined122980158463801733Mouse
14747008Mancz10_mmandible centroid size 10 (mouse)122986352263863522Mouse
10402492Dipa8_mdrug induced psychomotor activation 8 (mouse)Not determined123493387268934019Mouse
1300818Bbaa10_mB.burgdorferi-associated arthritis 10 (mouse)Not determined123509100465511019Mouse
4142002Tbqt3_mtibia bone quality traits 3 (mouse)Not determined1235285496109936243Mouse
1357479Splwt1_mspleen weight 1 (mouse)Not determined124169317590887526Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:404
Count of miRNA genes:183
Interacting mature miRNAs:193
Transcripts:ENSMUST00000042052, ENSMUST00000179265
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001405181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001405182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001405183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001405184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001405185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001405186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001405187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_144788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011244049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011244050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011244051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017315008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036157282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036157283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036157285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036157286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036157287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC157213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC159644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK042387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK044788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK051619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK077185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK085720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK173106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC010205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC031446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC048868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC089310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000042052   ⟹   ENSMUSP00000046766
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1251,790,505 - 51,876,319 (-)Ensembl
GRCm38.p6 Ensembl1251,743,722 - 51,829,536 (-)Ensembl
RefSeq Acc Id: ENSMUST00000179265   ⟹   ENSMUSP00000136449
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1251,790,505 - 51,876,319 (-)Ensembl
GRCm38.p6 Ensembl1251,743,722 - 51,829,536 (-)Ensembl
RefSeq Acc Id: ENSMUST00000217804
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1251,872,966 - 51,876,101 (-)Ensembl
GRCm38.p6 Ensembl1251,826,183 - 51,829,318 (-)Ensembl
RefSeq Acc Id: ENSMUST00000218626
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1251,804,821 - 51,812,014 (-)Ensembl
GRCm38.p6 Ensembl1251,758,038 - 51,765,231 (-)Ensembl
RefSeq Acc Id: ENSMUST00000220098
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1251,826,790 - 51,829,364 (-)Ensembl
GRCm38.p6 Ensembl1251,780,007 - 51,782,581 (-)Ensembl
RefSeq Acc Id: NM_144788   ⟹   NP_659037
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391251,790,505 - 51,876,319 (-)NCBI
GRCm381251,743,722 - 51,829,536 (-)NCBI
MGSCv371252,844,709 - 52,930,523 (-)RGD
Celera1253,048,069 - 53,133,676 (-)RGD
cM Map12 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011244049   ⟹   XP_011242351
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391251,790,504 - 51,876,540 (-)NCBI
GRCm381251,743,721 - 51,829,757 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011244050   ⟹   XP_011242352
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391251,790,504 - 51,876,540 (-)NCBI
GRCm381251,743,721 - 51,829,757 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011244051   ⟹   XP_011242353
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391251,790,504 - 51,876,540 (-)NCBI
GRCm381251,743,721 - 51,829,757 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017315008   ⟹   XP_017170497
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391251,790,504 - 51,876,540 (-)NCBI
GRCm381251,743,721 - 51,829,757 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036157282   ⟹   XP_036013175
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391251,790,504 - 51,876,540 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036157283   ⟹   XP_036013176
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391251,790,504 - 51,876,540 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036157285   ⟹   XP_036013178
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391251,790,504 - 51,876,540 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036157286   ⟹   XP_036013179
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391251,790,504 - 51,876,540 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036157287   ⟹   XP_036013180
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391251,790,504 - 51,876,540 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001392110 (Get FASTA)   NCBI Sequence Viewer  
  NP_001392111 (Get FASTA)   NCBI Sequence Viewer  
  NP_001392112 (Get FASTA)   NCBI Sequence Viewer  
  NP_001392113 (Get FASTA)   NCBI Sequence Viewer  
  NP_001392114 (Get FASTA)   NCBI Sequence Viewer  
  NP_001392115 (Get FASTA)   NCBI Sequence Viewer  
  NP_001392116 (Get FASTA)   NCBI Sequence Viewer  
  NP_659037 (Get FASTA)   NCBI Sequence Viewer  
  XP_011242351 (Get FASTA)   NCBI Sequence Viewer  
  XP_011242352 (Get FASTA)   NCBI Sequence Viewer  
  XP_011242353 (Get FASTA)   NCBI Sequence Viewer  
  XP_017170497 (Get FASTA)   NCBI Sequence Viewer  
  XP_036013175 (Get FASTA)   NCBI Sequence Viewer  
  XP_036013176 (Get FASTA)   NCBI Sequence Viewer  
  XP_036013178 (Get FASTA)   NCBI Sequence Viewer  
  XP_036013179 (Get FASTA)   NCBI Sequence Viewer  
  XP_036013180 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH10205 (Get FASTA)   NCBI Sequence Viewer  
  AAH31446 (Get FASTA)   NCBI Sequence Viewer  
  AAH89310 (Get FASTA)   NCBI Sequence Viewer  
  BAC36667 (Get FASTA)   NCBI Sequence Viewer  
  BAD32384 (Get FASTA)   NCBI Sequence Viewer  
  BAE24902 (Get FASTA)   NCBI Sequence Viewer  
  BAE32138 (Get FASTA)   NCBI Sequence Viewer  
  BAE41193 (Get FASTA)   NCBI Sequence Viewer  
  BAE41253 (Get FASTA)   NCBI Sequence Viewer  
  BAE42946 (Get FASTA)   NCBI Sequence Viewer  
  Q69ZR2 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_659037   ⟸   NM_144788
- UniProtKB: F8WIE5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011242352   ⟸   XM_011244050
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011242351   ⟸   XM_011244049
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011242353   ⟸   XM_011244051
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017170497   ⟸   XM_017315008
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: ENSMUSP00000136449   ⟸   ENSMUST00000179265
RefSeq Acc Id: ENSMUSP00000046766   ⟸   ENSMUST00000042052
RefSeq Acc Id: XP_036013175   ⟸   XM_036157282
- Peptide Label: isoform X4
RefSeq Acc Id: XP_036013180   ⟸   XM_036157287
- Peptide Label: isoform X9
RefSeq Acc Id: XP_036013179   ⟸   XM_036157286
- Peptide Label: isoform X8
RefSeq Acc Id: XP_036013178   ⟸   XM_036157285
- Peptide Label: isoform X7
RefSeq Acc Id: XP_036013176   ⟸   XM_036157283
- Peptide Label: isoform X6
Protein Domains
HECT   MIB/HERC2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q69ZR2-F1-model_v2 AlphaFold Q69ZR2 1-2618 view protein structure

Promoters
RGD ID:8678250
Promoter ID:EPDNEW_M17155
Type:initiation region
Name:Hectd1_2
Description:Mus musculus HECT domain E3 ubiquitin protein ligase 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M17156  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381251,829,308 - 51,829,368EPDNEW
RGD ID:8678252
Promoter ID:EPDNEW_M17156
Type:initiation region
Name:Hectd1_1
Description:Mus musculus HECT domain E3 ubiquitin protein ligase 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M17155  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381251,829,537 - 51,829,597EPDNEW
RGD ID:6823004
Promoter ID:MM_KWN:11616
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:AK033420_GM5785,   ENSMUST00000042052,   NM_144788,   UC007NMZ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361252,930,251 - 52,933,902 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2384768 AgrOrtholog
Ensembl Genes ENSMUSG00000035247 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000046766 ENTREZGENE
  ENSMUSP00000046766.9 UniProtKB/TrEMBL
  ENSMUSP00000136449 UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000042052 ENTREZGENE
  ENSMUST00000042052.9 UniProtKB/TrEMBL
  ENSMUST00000179265 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.25.40.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARM-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FKBP3_BTHB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Galactose-bd-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HECT_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hect_E3_ubiquitin_ligase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HECTD1/TRIP12-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Mib_Herc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Mib_Herc2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SUN_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:207304 UniProtKB/TrEMBL
MGD MGI:2384768 ENTREZGENE
NCBI Gene 207304 ENTREZGENE
PANTHER PTHR45670 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BTHB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HECT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIB_HERC2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sad1_UNC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hectd1 PhenoGen
PROSITE ANK_REP_REGION UniProtKB/Swiss-Prot
  ANK_REPEAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HECT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIB_HERC2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ANK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HECTc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF159034 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48371 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48403 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49785 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56204 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt F8WIE5 ENTREZGENE, UniProtKB/TrEMBL
  HECD1_MOUSE UniProtKB/Swiss-Prot
  Q05BY9_MOUSE UniProtKB/TrEMBL
  Q3T9S4_MOUSE UniProtKB/TrEMBL
  Q3TEJ5_MOUSE UniProtKB/TrEMBL
  Q3TEQ5_MOUSE UniProtKB/TrEMBL
  Q3U5E1_MOUSE UniProtKB/TrEMBL
  Q3UQY6_MOUSE UniProtKB/TrEMBL
  Q5EBQ8_MOUSE UniProtKB/TrEMBL
  Q69ZR2 ENTREZGENE
  Q8C5S2_MOUSE UniProtKB/TrEMBL
  Q91Z48_MOUSE UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-05-23 Hectd1  HECT domain E3 ubiquitin protein ligase 1    HECT domain containing 1  Symbol and/or name change 5135510 APPROVED