Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ptprq (protein tyrosine phosphatase, receptor type, Q) Mus musculus
Symbol: Ptprq
Name: protein tyrosine phosphatase, receptor type, Q
RGD ID: 736320
Description: Predicted to have protein tyrosine phosphatase activity. Involved in several processes, including detection of mechanical stimulus involved in sensory perception of sound; hematopoietic progenitor cell differentiation; and vestibular receptor cell morphogenesis. Localizes to stereocilium bundle. Is expressed in cochlea; crista ampullaris; inner ear vestibular component; macula of utricle; and saccule. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 73 and autosomal recessive nonsyndromic deafness 84A. Orthologous to human PTPRQ (protein tyrosine phosphatase receptor type Q); PARTICIPATES IN auditory mechanotransduction pathway; INTERACTS WITH folic acid; 17beta-estradiol (ortholog); 2,2',4,4'-Tetrabromodiphenyl ether (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: phosphatidylinositol phosphatase PTPRQ; phosphotidylinositol phosphatase PTPRQ; PTP-RQ; R-PTP-Q; receptor-type tyrosine-protein phosphatase Q
Homo sapiens (human) : PTPRQ (protein tyrosine phosphatase receptor type Q)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ptprq (protein tyrosine phosphatase, receptor type, Q)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptprq (protein tyrosine phosphatase receptor type Q)
Pan paniscus (bonobo/pygmy chimpanzee) : PTPRQ (protein tyrosine phosphatase receptor type Q)
Canis lupus familiaris (dog) : PTPRQ (protein tyrosine phosphatase receptor type Q)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptprq (protein tyrosine phosphatase receptor type Q)
Sus scrofa (pig) : PTPRQ (protein tyrosine phosphatase receptor type Q)
Chlorocebus sabaeus (African green monkey) : PTPRQ (protein tyrosine phosphatase receptor type Q)
Heterocephalus glaber (naked mole-rat) : Ptprq (protein tyrosine phosphatase receptor type Q)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm3910107,350,224 - 107,555,939 (-)NCBI
GRCm3810107,514,363 - 107,720,098 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10107,517,049 - 107,720,051 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710106,954,416 - 107,157,083 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610106,921,470 - 107,124,137 (-)NCBImm8
Celera10109,459,813 - 109,656,738 (-)NCBICelera
Cytogenetic Map10D1NCBI
cM Map1055.97NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ptprq
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736320
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.