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Gene: Acsl4 (acyl-CoA synthetase long-chain family member 4) Mus musculus
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Symbol: Acsl4
Name: acyl-CoA synthetase long-chain family member 4
Description: Exhibits long-chain fatty acid-CoA ligase activity. Involved in embryonic process involved in female pregnancy and neuron differentiation. Localizes to mitochondrion. Human ortholog(s) of this gene implicated in intellectual disability and non-syndromic X-linked intellectual disability. Is expressed in several structures, including alimentary system; integumental system; limb mesenchyme; nervous system; and sensory organ. Orthologous to human ACSL4 (acyl-CoA synthetase long chain family member 4); PARTICIPATES IN fatty acid beta degradation pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2-butoxyethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9430020A05Rik; ACS4; arachidonate--CoA ligase; AU018108; Facl4; fatty acid-Coenzyme A ligase, long chain 4; LACS 4; Lacs4; long-chain acyl-CoA synthetase 4; long-chain-fatty-acid--CoA ligase 4; mACS4
Orthologs:
Homo sapiens (human) : ACSL4 (acyl-CoA synthetase long chain family member 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Acsl4 (acyl-CoA synthetase long-chain family member 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acsl4 (acyl-CoA synthetase long chain family member 4)
Pan paniscus (bonobo/pygmy chimpanzee) : ACSL4 (acyl-CoA synthetase long chain family member 4)
Canis lupus familiaris (dog) : ACSL4 (acyl-CoA synthetase long chain family member 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acsl4 (acyl-CoA synthetase long chain family member 4)
Sus scrofa (pig) : ACSL4 (acyl-CoA synthetase long chain family member 4)
Chlorocebus sabaeus (African green monkey) : ACSL4 (acyl-CoA synthetase long chain family member 4)
Heterocephalus glaber (naked mole-rat) : Acsl4 (acyl-CoA synthetase long chain family member 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 EnsemblX142,317,993 - 142,390,535 (-)EnsemblGRCm38mm10GRCm38
GRCm38X142,317,993 - 142,390,802 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X138,752,536 - 138,825,078 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X137,564,361 - 137,636,903 (-)NCBImm8
CeleraX126,313,470 - 126,386,150 (-)NCBICelera
Cytogenetic MapXF2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Acsl4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69444
Created: 2001-11-27
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.