(+)-dexrazoxane multiple interactions EXP 6480464 Dexrazoxane inhibits the reaction [Cyclophosphamide results in increased expression of ACSL4 protein] CTD PMID:37690746 1,2-dimethylhydrazine decreases expression EXP 6480464 1 and 2-Dimethylhydrazine results in decreased expression of ACSL4 mRNA CTD PMID:22206623 1,3-dichloropropan-2-ol increases expression EXP 6480464 1 and 3-dichloro-2-propanol results in increased expression of ACSL4 protein CTD PMID:35870111 1,3-dichloropropan-2-ol increases expression ISO ACSL4 (Homo sapiens) 6480464 1 and 3-dichloro-2-propanol results in increased expression of ACSL4 protein CTD PMID:35870111 1,3-dichloropropan-2-ol multiple interactions ISO ACSL4 (Homo sapiens) 6480464 [Thiazoles binds to indoline] promotes the reaction [1 more ... CTD PMID:35870111 1-chloro-2,4-dinitrobenzene affects binding ISO ACSL4 (Homo sapiens) 6480464 Dinitrochlorobenzene binds to ACSL4 protein CTD PMID:32991956 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions EXP 6480464 3-Hydroxybutyric Acid inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:36435477 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases expression EXP 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:36435477 17alpha-ethynylestradiol increases expression ISO Acsl4 (Rattus norvegicus) 6480464 Ethinyl Estradiol results in increased expression of ACSL4 mRNA CTD PMID:17108234 17beta-estradiol multiple interactions ISO Acsl4 (Rattus norvegicus) 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of ACSL4 mRNA and [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in decreased expression of ACSL4 mRNA CTD PMID:26496021 and PMID:32741896 17beta-estradiol decreases expression ISO Acsl4 (Rattus norvegicus) 6480464 Estradiol results in decreased expression of ACSL4 mRNA CTD PMID:32145629 17beta-estradiol multiple interactions ISO ACSL4 (Homo sapiens) 6480464 [Estradiol co-treated with TGFB1 protein] results in increased expression of ACSL4 mRNA CTD PMID:30165855 17beta-estradiol 3-benzoate multiple interactions ISO Acsl4 (Rattus norvegicus) 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in decreased expression of ACSL4 mRNA CTD PMID:32741896 2,2',4,4'-Tetrabromodiphenyl ether affects expression EXP 6480464 2 more ... CTD PMID:30294300 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO ACSL4 (Homo sapiens) 6480464 2 more ... CTD PMID:31675489 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin binds to AHR protein] which results in decreased expression of ACSL4 mRNA CTD PMID:16214954 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Acsl4 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased expression of ACSL4 mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of ACSL4 mRNA CTD PMID:28922406 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO ACSL4 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of ACSL4 mRNA CTD PMID:26238291 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of ACSL4 mRNA CTD PMID:18796159 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Acsl4 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of ACSL4 mRNA CTD PMID:21215274 more ... 2,3,7,8-Tetrachlorodibenzofuran decreases expression ISO Acsl4 (Rattus norvegicus) 6480464 2 more ... CTD PMID:32109520 2,4,6-tribromophenol decreases expression ISO ACSL4 (Homo sapiens) 6480464 2 more ... CTD PMID:31675489 2,4-dinitrotoluene affects expression ISO Acsl4 (Rattus norvegicus) 6480464 2 and 4-dinitrotoluene affects the expression of ACSL4 mRNA CTD PMID:21346803 2-butoxyethanol increases expression EXP 6480464 n-butoxyethanol results in increased expression of ACSL4 mRNA CTD PMID:19812364 2-hydroxypropanoic acid increases expression ISO ACSL4 (Homo sapiens) 6480464 Lactic Acid results in increased expression of ACSL4 mRNA CTD PMID:30851411 3,3',5,5'-tetrabromobisphenol A decreases expression ISO ACSL4 (Homo sapiens) 6480464 tetrabromobisphenol A results in decreased expression of ACSL4 protein CTD PMID:31675489 3-chloropropane-1,2-diol increases expression ISO Acsl4 (Rattus norvegicus) 6480464 alpha-Chlorohydrin results in increased expression of ACSL4 protein CTD PMID:34915118 3-hydroxybutyric acid multiple interactions EXP 6480464 3-Hydroxybutyric Acid affects the reaction [ZFP36 protein affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of ACSL4 protein]] more ... CTD PMID:36435477 3-isobutyl-1-methyl-7H-xanthine multiple interactions EXP 6480464 [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ACSL4 mRNA CTD PMID:16054899 3-methylcholanthrene multiple interactions ISO ACSL4 (Homo sapiens) 6480464 Methylcholanthrene promotes the reaction [AHR protein binds to ACSL4 promoter] CTD PMID:20348232 3H-1,2-dithiole-3-thione decreases expression ISO Acsl4 (Rattus norvegicus) 6480464 1 and 2-dithiol-3-thione results in decreased expression of ACSL4 mRNA CTD PMID:19162173 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of ACSL4 mRNA CTD PMID:18648102 4,4'-sulfonyldiphenol increases expression ISO ACSL4 (Homo sapiens) 6480464 bisphenol S results in increased expression of ACSL4 protein CTD PMID:34186270 4,4'-sulfonyldiphenol increases methylation EXP 6480464 bisphenol S results in increased methylation of ACSL4 gene CTD PMID:31683443 4-hydroxyphenyl retinamide increases expression EXP 6480464 Fenretinide results in increased expression of ACSL4 mRNA CTD PMID:28973697 4-phenylbutyric acid multiple interactions ISO ACSL4 (Homo sapiens) 6480464 4-phenylbutyric acid inhibits the reaction [Particulate Matter results in increased expression of ACSL4 protein] CTD PMID:36700298 6-propyl-2-thiouracil decreases expression ISO Acsl4 (Rattus norvegicus) 6480464 Propylthiouracil results in decreased expression of ACSL4 mRNA CTD PMID:33150595 6-propyl-2-thiouracil increases methylation ISO Acsl4 (Rattus norvegicus) 6480464 Propylthiouracil results in increased methylation of ACSL4 promoter CTD PMID:33150595 acrolein increases expression EXP 6480464 Acrolein results in increased expression of ACSL4 protein CTD PMID:34813903 acrolein multiple interactions EXP 6480464 7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2 more ... CTD PMID:34813903 aflatoxin B1 decreases expression ISO ACSL4 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of ACSL4 mRNA CTD PMID:22100608 aflatoxin B1 increases expression ISO Acsl4 (Rattus norvegicus) 6480464 Aflatoxin B1 results in increased expression of ACSL4 protein CTD PMID:34116104 aflatoxin B1 multiple interactions ISO Acsl4 (Rattus norvegicus) 6480464 [2-hydroxy-4-methylselenobutanoic acid results in increased abundance of Selenium] inhibits the reaction [Aflatoxin B1 results in increased expression of ACSL4 protein] CTD PMID:34116104 all-trans-retinoic acid increases expression ISO ACSL4 (Homo sapiens) 6480464 Tretinoin results in increased expression of ACSL4 mRNA CTD PMID:33167477 ammonium chloride affects expression ISO Acsl4 (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of ACSL4 mRNA CTD PMID:16483693 amphetamine increases expression ISO Acsl4 (Rattus norvegicus) 6480464 Amphetamine results in increased expression of ACSL4 mRNA CTD PMID:30779732 Angoline multiple interactions EXP 6480464 angoline inhibits the reaction [monobutyl phthalate results in increased expression of ACSL4 protein] CTD PMID:37121744 apigenin multiple interactions EXP 6480464 Apigenin inhibits the reaction [Diethylhexyl Phthalate results in increased expression of ACSL4 mRNA] and Apigenin inhibits the reaction [Diethylhexyl Phthalate results in increased expression of ACSL4 protein] CTD PMID:35500696 aristolochic acid A decreases expression ISO ACSL4 (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of ACSL4 mRNA CTD PMID:33212167 arsenite(3-) multiple interactions ISO ACSL4 (Homo sapiens) 6480464 arsenite inhibits the reaction [G3BP1 protein binds to ACSL4 mRNA] CTD PMID:32406909 aurantio-obtusin increases expression ISO ACSL4 (Homo sapiens) 6480464 aurantio-obtusin results in increased expression of ACSL4 protein CTD PMID:35995123 beauvericin multiple interactions ISO ACSL4 (Homo sapiens) 6480464 [beauvericin co-treated with enniatins] results in decreased expression of ACSL4 protein CTD PMID:32407736 benzalkonium chloride increases expression EXP 6480464 Benzalkonium Compounds results in increased expression of ACSL4 mRNA CTD PMID:31199489 benzo[a]pyrene decreases expression ISO ACSL4 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of ACSL4 mRNA and Benzo(a)pyrene results in decreased expression of ACSL4 protein CTD PMID:22316170 more ... benzo[a]pyrene affects methylation ISO ACSL4 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of ACSL4 5' UTR more ... CTD PMID:27901495 and PMID:30157460 benzo[a]pyrene increases methylation ISO ACSL4 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of ACSL4 exon CTD PMID:27901495 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of ACSL4 mRNA CTD PMID:19770486 and PMID:23735875 benzo[e]pyrene decreases methylation ISO ACSL4 (Homo sapiens) 6480464 benzo(e)pyrene results in decreased methylation of ACSL4 intron CTD PMID:30157460 beryllium sulfate multiple interactions ISO ACSL4 (Homo sapiens) 6480464 [sodium bisulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [beryllium sulfate results in increased expression of ACSL4 mRNA] more ... CTD PMID:36843388 beryllium sulfate increases expression ISO ACSL4 (Homo sapiens) 6480464 beryllium sulfate results in increased expression of ACSL4 mRNA CTD PMID:36843388 bezafibrate increases expression EXP 6480464 Bezafibrate results in increased expression of ACSL4 mRNA CTD PMID:17118139 bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of ACSL4 mRNA and Diethylhexyl Phthalate results in increased expression of ACSL4 protein CTD PMID:34863575 and PMID:35500696 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 Apigenin inhibits the reaction [Diethylhexyl Phthalate results in increased expression of ACSL4 mRNA] and Apigenin inhibits the reaction [Diethylhexyl Phthalate results in increased expression of ACSL4 protein] CTD PMID:35500696 bisphenol A multiple interactions ISO Acsl4 (Rattus norvegicus) 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of ACSL4 mRNA and [bisphenol A co-treated with Testosterone] results in increased expression of ACSL4 mRNA CTD PMID:26496021 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of ACSL4 mRNA and bisphenol A results in increased expression of ACSL4 protein CTD PMID:36153926 bisphenol A increases expression ISO ACSL4 (Homo sapiens) 6480464 bisphenol A results in increased expression of ACSL4 protein CTD PMID:34186270 bisphenol A increases expression ISO Acsl4 (Rattus norvegicus) 6480464 bisphenol A results in increased expression of ACSL4 mRNA CTD PMID:33296240 bisphenol A decreases expression ISO Acsl4 (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of ACSL4 mRNA CTD PMID:30816183 more ... bisphenol A decreases expression ISO ACSL4 (Homo sapiens) 6480464 bisphenol A results in decreased expression of ACSL4 mRNA CTD PMID:29275510 bisphenol A affects expression ISO ACSL4 (Homo sapiens) 6480464 bisphenol A affects the expression of ACSL4 mRNA CTD PMID:30903817 bisphenol A increases methylation ISO Acsl4 (Rattus norvegicus) 6480464 bisphenol A results in increased methylation of ACSL4 gene CTD PMID:28505145 bisphenol A affects expression ISO Acsl4 (Rattus norvegicus) 6480464 bisphenol A affects the expression of ACSL4 mRNA CTD PMID:25181051 Bisphenol B increases expression ISO ACSL4 (Homo sapiens) 6480464 bisphenol B results in increased expression of ACSL4 protein CTD PMID:34186270 bisphenol F increases expression ISO ACSL4 (Homo sapiens) 6480464 bisphenol F results in increased expression of ACSL4 protein CTD PMID:34186270 buspirone increases expression ISO Acsl4 (Rattus norvegicus) 6480464 Buspirone results in increased expression of ACSL4 mRNA CTD PMID:24136188 cadmium atom multiple interactions ISO Acsl4 (Rattus norvegicus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ACSL4 mRNA and MIR34A mRNA affects the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ACSL4 mRNA] CTD PMID:34558789 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of ACSL4 mRNA CTD PMID:24982889 cadmium dichloride multiple interactions ISO Acsl4 (Rattus norvegicus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ACSL4 mRNA and MIR34A mRNA affects the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ACSL4 mRNA] CTD PMID:34558789 cadmium sulfate multiple interactions ISO ACSL4 (Homo sapiens) 6480464 [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of ACSL4 mRNA CTD PMID:18654764 caffeine decreases expression ISO ACSL4 (Homo sapiens) 6480464 Caffeine results in decreased expression of ACSL4 protein CTD PMID:31195006 caffeine affects phosphorylation ISO ACSL4 (Homo sapiens) 6480464 Caffeine affects the phosphorylation of ACSL4 protein CTD PMID:35688186 calciol increases expression EXP 6480464 Cholecalciferol results in increased expression of ACSL4 mRNA CTD PMID:16508948 cantharidin increases expression EXP 6480464 Cantharidin results in increased expression of ACSL4 mRNA CTD PMID:36907384 carbon nanotube decreases expression EXP 6480464 Nanotubes and Carbon analog results in decreased expression of ACSL4 mRNA CTD PMID:25620056 carbon nanotube increases expression EXP 6480464 Nanotubes more ... CTD PMID:25554681 chloroquine multiple interactions ISO ACSL4 (Homo sapiens) 6480464 Chloroquine inhibits the reaction [Particulate Matter results in increased expression of ACSL4 protein] CTD PMID:36700298 choline multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ACSL4 mRNA CTD PMID:20938992 chromium(6+) affects expression EXP 6480464 chromium hexavalent ion affects the expression of ACSL4 mRNA CTD PMID:28472532 cisplatin multiple interactions ISO ACSL4 (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of ACSL4 mRNA CTD PMID:27392435 clofibrate increases expression ISO Acsl4 (Rattus norvegicus) 6480464 Clofibrate results in increased expression of ACSL4 mRNA CTD PMID:18670166 and PMID:33983380 cobalt dichloride multiple interactions ISO ACSL4 (Homo sapiens) 6480464 [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of ACSL4 mRNA CTD PMID:18654764 cobalt dichloride decreases expression ISO ACSL4 (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of ACSL4 mRNA CTD PMID:19320972 cobalt dichloride decreases expression ISO Acsl4 (Rattus norvegicus) 6480464 cobaltous chloride results in decreased expression of ACSL4 mRNA CTD PMID:24386269 copper atom increases expression ISO Acsl4 (Rattus norvegicus) 6480464 Copper results in increased expression of ACSL4 mRNA CTD PMID:22465980 copper(0) increases expression ISO Acsl4 (Rattus norvegicus) 6480464 Copper results in increased expression of ACSL4 mRNA CTD PMID:22465980 copper(II) sulfate decreases expression ISO ACSL4 (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of ACSL4 mRNA CTD PMID:19549813 CU-O LINKAGE decreases expression ISO ACSL4 (Homo sapiens) 6480464 cupric oxide results in decreased expression of ACSL4 protein CTD PMID:25470785 Cuprizon decreases expression ISO Acsl4 (Rattus norvegicus) 6480464 Cuprizone results in decreased expression of ACSL4 mRNA CTD PMID:26577399 cyclophosphamide multiple interactions EXP 6480464 Dexrazoxane inhibits the reaction [Cyclophosphamide results in increased expression of ACSL4 protein] CTD PMID:37690746 cyclophosphamide increases expression EXP 6480464 Cyclophosphamide results in increased expression of ACSL4 protein CTD PMID:37690746 deoxynivalenol decreases expression ISO ACSL4 (Homo sapiens) 6480464 deoxynivalenol results in decreased expression of ACSL4 protein CTD PMID:33890134 desferrioxamine B multiple interactions ISO ACSL4 (Homo sapiens) 6480464 Deferoxamine inhibits the reaction [beryllium sulfate results in increased expression of ACSL4 mRNA] CTD PMID:36843388 dexamethasone multiple interactions EXP 6480464 [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ACSL4 mRNA CTD PMID:16054899 dexamethasone multiple interactions ISO Acsl4 (Rattus norvegicus) 6480464 Testosterone inhibits the reaction [Dexamethasone results in increased expression of ACSL4 mRNA] CTD PMID:20032058 dexamethasone increases expression ISO Acsl4 (Rattus norvegicus) 6480464 Dexamethasone results in increased expression of ACSL4 mRNA CTD PMID:20032058 dibutyl phthalate decreases expression ISO Acsl4 (Rattus norvegicus) 6480464 Dibutyl Phthalate results in decreased expression of ACSL4 mRNA CTD PMID:21266533 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of ACSL4 mRNA CTD PMID:21266533 dibutyl phthalate increases expression ISO Acsl4 (Rattus norvegicus) 6480464 Dibutyl Phthalate results in increased expression of ACSL4 mRNA CTD PMID:21266533 dichloroacetic acid increases expression EXP 6480464 Dichloroacetic Acid results in increased expression of ACSL4 mRNA CTD PMID:28962523 dimethyl fumarate multiple interactions ISO ACSL4 (Homo sapiens) 6480464 Dimethyl Fumarate inhibits the reaction [1 and 3-dichloro-2-propanol results in increased expression of ACSL4 protein] CTD PMID:35870111 diuron decreases expression ISO Acsl4 (Rattus norvegicus) 6480464 Diuron results in decreased expression of ACSL4 mRNA CTD PMID:21551480 dorsomorphin multiple interactions ISO ACSL4 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ACSL4 mRNA CTD PMID:27188386 doxorubicin decreases expression ISO ACSL4 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of ACSL4 mRNA CTD PMID:29803840 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of ACSL4 protein CTD PMID:36195186 doxorubicin multiple interactions ISO Acsl4 (Rattus norvegicus) 6480464 Melatonin inhibits the reaction [Doxorubicin results in increased expression of ACSL4 protein] more ... CTD PMID:35093381 doxorubicin increases expression ISO Acsl4 (Rattus norvegicus) 6480464 Doxorubicin results in increased expression of ACSL4 protein CTD PMID:35093381 and PMID:36195186 elemental selenium multiple interactions ISO Acsl4 (Rattus norvegicus) 6480464 [2-hydroxy-4-methylselenobutanoic acid results in increased abundance of Selenium] inhibits the reaction [Aflatoxin B1 results in increased expression of ACSL4 protein] and [2-hydroxy-4-methylselenobutanoic acid results in increased abundance of Selenium] which results in decreased expression of ACSL4 protein CTD PMID:34116104 enniatin multiple interactions ISO ACSL4 (Homo sapiens) 6480464 [beauvericin co-treated with enniatins] results in decreased expression of ACSL4 protein CTD PMID:32407736 enzyme inhibitor multiple interactions ISO ACSL4 (Homo sapiens) 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of ACSL4 protein CTD PMID:23301498 epoxiconazole decreases expression EXP 6480464 epoxiconazole results in decreased expression of ACSL4 mRNA CTD PMID:35436446 ethambutol multiple interactions ISO Acsl4 (Rattus norvegicus) 6480464 [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in increased expression of ACSL4 protein CTD PMID:36878459 ethanol increases expression EXP 6480464 Ethanol results in increased expression of ACSL4 protein CTD PMID:33017621 ethanol multiple interactions ISO ACSL4 (Homo sapiens) 6480464 [CYP2E1 protein affects the susceptibility to Ethanol] which affects the expression of ACSL4 protein and FXN protein affects the reaction [[CYP2E1 protein affects the susceptibility to Ethanol] which affects the expression of ACSL4 protein] CTD PMID:33017621 ethyl methanesulfonate decreases expression ISO ACSL4 (Homo sapiens) 6480464 Ethyl Methanesulfonate results in decreased expression of ACSL4 mRNA CTD PMID:23649840 farnesol multiple interactions ISO ACSL4 (Homo sapiens) 6480464 [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACSL4 mRNA CTD PMID:30611723 fenofibrate increases expression EXP 6480464 Fenofibrate results in increased expression of ACSL4 mRNA CTD PMID:17118139 ferrostatin-1 multiple interactions EXP 6480464 ferrostatin-1 inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:34813903 more ... ferrostatin-1 multiple interactions ISO ACSL4 (Homo sapiens) 6480464 ferrostatin-1 inhibits the reaction [1 and 3-dichloro-2-propanol results in increased expression of ACSL4 protein] CTD PMID:35870111 fluoranthene multiple interactions EXP 6480464 [1-methylanthracene co-treated with fluoranthene] results in increased expression of ACSL4 mRNA CTD PMID:28329830 fluoxetine increases expression ISO ACSL4 (Homo sapiens) 6480464 Fluoxetine results in increased expression of ACSL4 mRNA CTD PMID:37386098 folic acid multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ACSL4 mRNA CTD PMID:20938992 formaldehyde decreases expression ISO ACSL4 (Homo sapiens) 6480464 Formaldehyde results in decreased expression of ACSL4 mRNA CTD PMID:23649840 Gastrodin multiple interactions EXP 6480464 gastrodin inhibits the reaction [Glutamic Acid results in increased expression of ACSL4 protein] CTD PMID:31698019 glutathione increases expression ISO Acsl4 (Rattus norvegicus) 6480464 Glutathione deficiency results in increased expression of ACSL4 mRNA CTD PMID:15345336 glycidol increases methylation ISO Acsl4 (Rattus norvegicus) 6480464 glycidol results in increased methylation of ACSL4 promoter CTD PMID:33150595 glycidol decreases expression ISO Acsl4 (Rattus norvegicus) 6480464 glycidol results in decreased expression of ACSL4 mRNA CTD PMID:33150645 GW 4064 multiple interactions ISO ACSL4 (Homo sapiens) 6480464 [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACSL4 mRNA CTD PMID:30611723 GW 7647 increases expression ISO ACSL4 (Homo sapiens) 6480464 GW 7647 results in increased expression of ACSL4 mRNA CTD PMID:30611723 GW 7647 multiple interactions ISO ACSL4 (Homo sapiens) 6480464 [GW 7647 co-treated with Oleic Acid] results in increased expression of ACSL4 mRNA CTD PMID:30611723 hexadecanoic acid multiple interactions ISO ACSL4 (Homo sapiens) 6480464 [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ACSL4 mRNA CTD PMID:30547786 hydrogen sulfide multiple interactions ISO ACSL4 (Homo sapiens) 6480464 [sodium bisulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [beryllium sulfate results in increased expression of ACSL4 mRNA] CTD PMID:36843388 indoline multiple interactions ISO ACSL4 (Homo sapiens) 6480464 [Thiazoles binds to indoline] promotes the reaction [1 and 3-dichloro-2-propanol results in increased expression of ACSL4 protein] CTD PMID:35870111 indometacin affects expression ISO Acsl4 (Rattus norvegicus) 6480464 Indomethacin affects the expression of ACSL4 mRNA CTD PMID:36868495 isoniazide multiple interactions ISO Acsl4 (Rattus norvegicus) 6480464 [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in increased expression of ACSL4 protein CTD PMID:36878459 ivermectin decreases expression ISO ACSL4 (Homo sapiens) 6480464 Ivermectin results in decreased expression of ACSL4 protein CTD PMID:32959892 ketoconazole decreases expression ISO Acsl4 (Rattus norvegicus) 6480464 Ketoconazole results in decreased expression of ACSL4 mRNA CTD PMID:37077353 L-ascorbic acid decreases expression ISO Acsl4 (Rattus norvegicus) 6480464 Ascorbic Acid results in decreased expression of ACSL4 mRNA CTD PMID:15372504 L-glutamic acid increases expression EXP 6480464 Glutamic Acid results in increased expression of ACSL4 protein CTD PMID:31698019 L-glutamic acid multiple interactions EXP 6480464 gastrodin inhibits the reaction [Glutamic Acid results in increased expression of ACSL4 protein] CTD PMID:31698019 L-methionine multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ACSL4 mRNA CTD PMID:20938992 lead(II) chloride multiple interactions ISO ACSL4 (Homo sapiens) 6480464 [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of ACSL4 mRNA CTD PMID:18654764 maneb multiple interactions EXP 6480464 [Maneb co-treated with Paraquat] results in decreased expression of ACSL4 mRNA CTD PMID:36117858 melatonin multiple interactions ISO Acsl4 (Rattus norvegicus) 6480464 Melatonin inhibits the reaction [Doxorubicin results in increased expression of ACSL4 protein] more ... CTD PMID:35093381 methapyrilene decreases methylation ISO ACSL4 (Homo sapiens) 6480464 Methapyrilene results in decreased methylation of ACSL4 intron CTD PMID:30157460 methotrexate increases expression ISO ACSL4 (Homo sapiens) 6480464 Methotrexate results in increased expression of ACSL4 mRNA CTD PMID:17400583 methyl methanesulfonate decreases expression ISO ACSL4 (Homo sapiens) 6480464 Methyl Methanesulfonate results in decreased expression of ACSL4 mRNA CTD PMID:23649840 methylmercury chloride decreases expression ISO ACSL4 (Homo sapiens) 6480464 methylmercuric chloride results in decreased expression of ACSL4 mRNA CTD PMID:23179753 and PMID:28001369 mono(2-ethylhexyl) phthalate decreases expression EXP 6480464 mono-(2-ethylhexyl)phthalate results in decreased expression of ACSL4 mRNA CTD PMID:22401849 mono(2-ethylhexyl) phthalate multiple interactions EXP 6480464 ferrostatin-1 inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of ACSL4 protein] and HIF1A gene mutant form inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of ACSL4 protein] CTD PMID:34863575 mono(2-ethylhexyl) phthalate increases expression EXP 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of ACSL4 mRNA and mono-(2-ethylhexyl)phthalate results in increased expression of ACSL4 protein CTD PMID:34863575 Monobutylphthalate increases expression EXP 6480464 monobutyl phthalate results in increased expression of ACSL4 protein CTD PMID:37121744 Monobutylphthalate multiple interactions EXP 6480464 angoline inhibits the reaction [monobutyl phthalate results in increased expression of ACSL4 protein] and ferrostatin-1 inhibits the reaction [monobutyl phthalate results in increased expression of ACSL4 protein] CTD PMID:37121744 N-methyl-4-phenylpyridinium increases expression ISO Acsl4 (Rattus norvegicus) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of ACSL4 mRNA CTD PMID:16026605 N-methyl-4-phenylpyridinium multiple interactions EXP 6480464 3-Hydroxybutyric Acid affects the reaction [ZFP36 protein affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of ACSL4 protein]] more ... CTD PMID:36435477 N-methyl-4-phenylpyridinium increases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in increased expression of ACSL4 protein CTD PMID:36435477 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of ACSL4 mRNA CTD PMID:24535843 nefazodone increases expression ISO Acsl4 (Rattus norvegicus) 6480464 nefazodone results in increased expression of ACSL4 mRNA CTD PMID:24136188 nickel atom increases expression ISO ACSL4 (Homo sapiens) 6480464 Nickel results in increased expression of ACSL4 mRNA CTD PMID:24768652 and PMID:25583101 nimesulide increases expression ISO Acsl4 (Rattus norvegicus) 6480464 nimesulide results in increased expression of ACSL4 mRNA CTD PMID:24136188 O-methyleugenol decreases expression ISO ACSL4 (Homo sapiens) 6480464 methyleugenol results in decreased expression of ACSL4 mRNA CTD PMID:32234424 obeticholic acid increases expression ISO ACSL4 (Homo sapiens) 6480464 obeticholic acid results in increased expression of ACSL4 mRNA CTD PMID:27939613 oleic acid multiple interactions ISO ACSL4 (Homo sapiens) 6480464 [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACSL4 mRNA more ... CTD PMID:30547786 and PMID:30611723 ozone multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of ACSL4 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in increased expression of ACSL4 mRNA CTD PMID:34911549 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of ACSL4 mRNA CTD PMID:17562736 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of ACSL4 mRNA CTD PMID:34401974 paracetamol decreases expression ISO ACSL4 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of ACSL4 mRNA CTD PMID:29067470 paraquat increases expression ISO Acsl4 (Rattus norvegicus) 6480464 Paraquat results in increased expression of ACSL4 mRNA CTD PMID:32680482 paraquat multiple interactions EXP 6480464 [Maneb co-treated with Paraquat] results in decreased expression of ACSL4 mRNA CTD PMID:36117858 perfluorohexanesulfonic acid increases expression EXP 6480464 perfluorohexanesulfonic acid results in increased expression of ACSL4 mRNA CTD PMID:21705711 perfluorononanoic acid decreases expression ISO ACSL4 (Homo sapiens) 6480464 perfluoro-n-nonanoic acid results in decreased expression of ACSL4 mRNA CTD PMID:32588087 perfluorooctane-1-sulfonic acid affects expression EXP 6480464 perfluorooctane sulfonic acid affects the expression of ACSL4 mRNA CTD PMID:19429403 perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of ACSL4 mRNA CTD PMID:36331819 perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of ACSL4 mRNA CTD PMID:20936131 and PMID:21705711 perfluorooctane-1-sulfonic acid increases expression ISO Acsl4 (Rattus norvegicus) 6480464 perfluorooctane sulfonic acid results in increased expression of ACSL4 mRNA CTD PMID:19162173 perfluorooctanoic acid affects expression EXP 6480464 perfluorooctanoic acid affects the expression of ACSL4 mRNA CTD PMID:19429403 perfluorooctanoic acid increases expression ISO ACSL4 (Homo sapiens) 6480464 perfluorooctanoic acid results in increased expression of ACSL4 mRNA CTD PMID:37738295 perfluorooctanoic acid multiple interactions EXP 6480464 PPARA protein promotes the reaction [perfluorooctanoic acid results in increased expression of ACSL4 mRNA] CTD PMID:18467677 and PMID:20936131 perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of ACSL4 mRNA CTD PMID:17681415 more ... phenobarbital multiple interactions EXP 6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of ACSL4 mRNA] CTD PMID:19482888 phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of ACSL4 mRNA CTD PMID:23091169 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of ACSL4 mRNA CTD PMID:19482888 phenobarbital decreases expression EXP 6480464 Phenobarbital results in decreased expression of ACSL4 mRNA CTD PMID:19363144 pirinixic acid multiple interactions EXP 6480464 [pirinixic acid co-treated with PPARA] results in increased expression of ACSL4 mRNA and PPARA protein promotes the reaction [pirinixic acid results in increased expression of ACSL4 mRNA] CTD PMID:17950772 more ... pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of ACSL4 mRNA CTD PMID:17118139 more ... pirinixic acid increases expression ISO Acsl4 (Rattus norvegicus) 6480464 pirinixic acid results in increased expression of ACSL4 mRNA CTD PMID:19162173 and PMID:33983380 pregnenolone 16alpha-carbonitrile decreases expression EXP 6480464 Pregnenolone Carbonitrile results in decreased expression of ACSL4 mRNA CTD PMID:28903501 pyrazinecarboxamide multiple interactions ISO Acsl4 (Rattus norvegicus) 6480464 [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in increased expression of ACSL4 protein CTD PMID:36878459 rac-lactic acid increases expression ISO ACSL4 (Homo sapiens) 6480464 Lactic Acid results in increased expression of ACSL4 mRNA CTD PMID:30851411 resveratrol multiple interactions ISO ACSL4 (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in increased expression of ACSL4 mRNA CTD PMID:23557933 resveratrol increases expression ISO ACSL4 (Homo sapiens) 6480464 Resveratrol results in increased expression of ACSL4 mRNA CTD PMID:37419272 resveratrol multiple interactions EXP 6480464 Resveratrol inhibits the reaction [Acrolein results in increased expression of ACSL4 protein] CTD PMID:34813903 rifampicin multiple interactions ISO Acsl4 (Rattus norvegicus) 6480464 [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in increased expression of ACSL4 protein CTD PMID:36878459 SB 431542 multiple interactions ISO ACSL4 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ACSL4 mRNA CTD PMID:27188386 selenium atom multiple interactions ISO Acsl4 (Rattus norvegicus) 6480464 [2-hydroxy-4-methylselenobutanoic acid results in increased abundance of Selenium] inhibits the reaction [Aflatoxin B1 results in increased expression of ACSL4 protein] and [2-hydroxy-4-methylselenobutanoic acid results in increased abundance of Selenium] which results in decreased expression of ACSL4 protein CTD PMID:34116104 senecionine decreases expression EXP 6480464 senecionine results in decreased expression of ACSL4 protein CTD PMID:35357534 sevoflurane increases expression ISO Acsl4 (Rattus norvegicus) 6480464 Sevoflurane results in increased expression of ACSL4 protein CTD PMID:37494465 sevoflurane multiple interactions ISO Acsl4 (Rattus norvegicus) 6480464 TBX2 protein affects the reaction [Sevoflurane results in increased expression of ACSL4 protein] CTD PMID:37494465 silicon dioxide increases expression ISO ACSL4 (Homo sapiens) 6480464 Silicon Dioxide analog results in increased expression of ACSL4 mRNA CTD PMID:25895662 sodium arsenate increases expression EXP 6480464 sodium arsenate results in increased expression of ACSL4 mRNA CTD PMID:21795629 sodium arsenite increases expression ISO Acsl4 (Rattus norvegicus) 6480464 sodium arsenite results in increased expression of ACSL4 mRNA and sodium arsenite results in increased expression of ACSL4 protein CTD PMID:32593899 sodium arsenite increases expression ISO ACSL4 (Homo sapiens) 6480464 sodium arsenite results in increased expression of ACSL4 protein CTD PMID:32593899 sodium arsenite multiple interactions ISO ACSL4 (Homo sapiens) 6480464 ACSL4 protein affects the reaction [sodium arsenite results in decreased expression of GPX4 protein] more ... CTD PMID:32593899 sodium fluoride increases expression EXP 6480464 Sodium Fluoride results in increased expression of ACSL4 mRNA CTD PMID:37245782 succimer multiple interactions EXP 6480464 [Succimer binds to Magnetite Nanoparticles] which results in increased expression of ACSL4 mRNA CTD PMID:21641980 testosterone multiple interactions ISO Acsl4 (Rattus norvegicus) 6480464 [bisphenol A co-treated with Testosterone] results in increased expression of ACSL4 mRNA more ... CTD PMID:20032058 more ... testosterone decreases expression EXP 6480464 Testosterone deficiency results in decreased expression of ACSL4 mRNA CTD PMID:33848595 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of ACSL4 mRNA CTD PMID:17484886 tetrachloromethane affects expression ISO Acsl4 (Rattus norvegicus) 6480464 Carbon Tetrachloride affects the expression of ACSL4 mRNA CTD PMID:16239168 tetradecane increases expression ISO Acsl4 (Rattus norvegicus) 6480464 n-tetradecane results in increased expression of ACSL4 protein CTD PMID:17337753 thiazoles multiple interactions ISO ACSL4 (Homo sapiens) 6480464 [Thiazoles binds to indoline] promotes the reaction [1 and 3-dichloro-2-propanol results in increased expression of ACSL4 protein] CTD PMID:35870111 thimerosal increases expression ISO ACSL4 (Homo sapiens) 6480464 Thimerosal results in increased expression of ACSL4 mRNA CTD PMID:27188386 titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of ACSL4 mRNA CTD PMID:23557971 topiramate decreases expression ISO Acsl4 (Rattus norvegicus) 6480464 topiramate results in decreased expression of ACSL4 mRNA CTD PMID:16979414 trichostatin A increases expression ISO ACSL4 (Homo sapiens) 6480464 trichostatin A results in increased expression of ACSL4 mRNA CTD PMID:26272509 trichostatin A multiple interactions ISO ACSL4 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ACSL4 mRNA CTD PMID:27188386 triclosan affects expression ISO ACSL4 (Homo sapiens) 6480464 Triclosan affects the expression of ACSL4 mRNA CTD PMID:31714634 trimellitic anhydride increases expression EXP 6480464 trimellitic anhydride results in increased expression of ACSL4 mRNA CTD PMID:19042947 triptonide decreases expression EXP 6480464 triptonide results in decreased expression of ACSL4 mRNA CTD PMID:33045310 troglitazone increases expression ISO Acsl4 (Rattus norvegicus) 6480464 troglitazone results in increased expression of ACSL4 mRNA CTD PMID:21515302 urethane decreases expression ISO ACSL4 (Homo sapiens) 6480464 Urethane results in decreased expression of ACSL4 mRNA CTD PMID:28818685 valproic acid increases methylation ISO ACSL4 (Homo sapiens) 6480464 Valproic Acid results in increased methylation of ACSL4 gene CTD PMID:29154799 valproic acid decreases expression ISO Acsl4 (Rattus norvegicus) 6480464 Valproic Acid results in decreased expression of ACSL4 mRNA CTD PMID:33150595 valproic acid increases methylation ISO Acsl4 (Rattus norvegicus) 6480464 Valproic Acid results in increased methylation of ACSL4 promoter CTD PMID:33150595 valproic acid decreases methylation ISO ACSL4 (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of ACSL4 gene CTD PMID:29501571 valproic acid decreases expression ISO ACSL4 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of ACSL4 mRNA CTD PMID:29501571 valproic acid increases expression ISO ACSL4 (Homo sapiens) 6480464 Valproic Acid results in increased expression of ACSL4 mRNA CTD PMID:23179753 vancomycin decreases expression EXP 6480464 Vancomycin results in decreased expression of ACSL4 mRNA CTD PMID:18930951 verteporfin multiple interactions ISO Acsl4 (Rattus norvegicus) 6480464 Verteporfin inhibits the reaction [Melatonin inhibits the reaction [Doxorubicin results in increased expression of ACSL4 protein]] CTD PMID:35093381 vinclozolin increases methylation ISO Acsl4 (Rattus norvegicus) 6480464 vinclozolin results in increased methylation of ACSL4 gene CTD PMID:31682807 vorinostat increases expression ISO ACSL4 (Homo sapiens) 6480464 vorinostat results in increased expression of ACSL4 mRNA CTD PMID:27188386
