Slc25a34 (solute carrier family 25, member 34) - Rat Genome Database

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Gene: Slc25a34 (solute carrier family 25, member 34) Mus musculus
Analyze
Symbol: Slc25a34
Name: solute carrier family 25, member 34
RGD ID: 1619669
MGI Page MGI
Description: Acts upstream of or within blastocyst hatching. Located in mitochondrion. Is expressed in early conceptus. Orthologous to human SLC25A34 (solute carrier family 25 member 34).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Gm1369; MGC107701; solute carrier family 25 member 34
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394141,346,130 - 141,351,202 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4141,346,135 - 141,351,132 (-)EnsemblGRCm39 Ensembl
GRCm384141,618,819 - 141,623,891 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4141,618,824 - 141,623,821 (-)EnsemblGRCm38mm10GRCm38
MGSCv374141,174,739 - 141,179,749 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364140,890,900 - 140,895,910 (-)NCBIMGSCv36mm8
Celera4143,441,650 - 143,447,213 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map474.64NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14681479   PMID:16141072   PMID:16141073   PMID:16602821   PMID:18614015  
PMID:27869233   PMID:35718058  


Genomics

Comparative Map Data
Slc25a34
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394141,346,130 - 141,351,202 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4141,346,135 - 141,351,132 (-)EnsemblGRCm39 Ensembl
GRCm384141,618,819 - 141,623,891 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4141,618,824 - 141,623,821 (-)EnsemblGRCm38mm10GRCm38
MGSCv374141,174,739 - 141,179,749 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364140,890,900 - 140,895,910 (-)NCBIMGSCv36mm8
Celera4143,441,650 - 143,447,213 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map474.64NCBI
SLC25A34
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38115,736,258 - 15,741,392 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl115,736,258 - 15,741,392 (+)EnsemblGRCh38hg38GRCh38
GRCh37116,062,753 - 16,067,887 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36115,935,396 - 15,940,471 (+)NCBINCBI36Build 36hg18NCBI36
Celera114,545,826 - 14,550,901 (+)NCBICelera
Cytogenetic Map1p36.21NCBI
HuRef114,581,786 - 14,586,858 (+)NCBIHuRef
CHM1_1115,861,410 - 15,866,482 (+)NCBICHM1_1
T2T-CHM13v2.0115,179,763 - 15,186,130 (+)NCBIT2T-CHM13v2.0
Slc25a34
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85159,215,120 - 159,219,892 (-)NCBIGRCr8
mRatBN7.25153,932,081 - 153,936,854 (-)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx5156,617,226 - 156,621,996 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05158,390,504 - 158,395,274 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05158,379,678 - 158,384,448 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05160,175,206 - 160,179,978 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5160,176,124 - 160,179,978 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05163,890,563 - 163,894,419 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45160,519,856 - 160,523,712 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15160,530,045 - 160,533,900 (-)NCBI
Celera5152,288,205 - 152,292,977 (-)NCBICelera
Cytogenetic Map5q36NCBI
Slc25a34
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555272,433,577 - 2,437,343 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555272,433,577 - 2,437,348 (-)NCBIChiLan1.0ChiLan1.0
SLC25A34
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21211,174,676 - 211,181,168 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11210,423,274 - 210,429,767 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0114,877,351 - 14,883,769 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1115,870,289 - 15,874,956 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl115,870,289 - 15,875,099 (+)Ensemblpanpan1.1panPan2
SLC25A34
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1281,859,294 - 81,864,808 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl281,860,234 - 81,863,494 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha278,397,257 - 78,402,075 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0282,507,877 - 82,512,692 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl282,507,895 - 82,512,066 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1279,261,239 - 79,266,057 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0280,279,274 - 80,284,086 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0281,345,216 - 81,349,965 (-)NCBIUU_Cfam_GSD_1.0
Slc25a34
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505837,541,409 - 37,546,539 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364743,367,695 - 3,370,133 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364743,367,374 - 3,371,315 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC25A34
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl674,909,705 - 74,914,426 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1674,909,637 - 74,914,430 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2669,389,608 - 69,394,491 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC25A34
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120116,564,687 - 116,568,695 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20116,565,024 - 116,567,981 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605420,096,900 - 20,103,467 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Slc25a34
213 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:788
Count of miRNA genes:424
Interacting mature miRNAs:530
Transcripts:ENSMUST00000038661
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155684457Mouse
25314312Syncl2_msynaptonemal complex length 2 (mouse)465718237146584457Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468018237150884457Mouse
1301823Bmd7_mbone mineral density 7 (mouse)Not determined488982069151654550Mouse
13208562Wght7_mweight 7 (mouse)490888237148084457Mouse
1301815Sles2_msystemic lupus erythmatosus suppressor 2 (mouse)Not determined494957579150676858Mouse
12910794Pwbwq8_mpost-weaning body weight QTL 8 (mouse)4105835310141433838Mouse
12910797Pwgrq4_mpre-weaning growth rate QTL 4 (mouse)4105835310141433838Mouse
12910808Pwbwq9_mpost-weaning body weight QTL 9 (mouse)4105835310141433838Mouse
12910813Pwbwq4_mpre-weaning body weight QTL 4 (mouse)4105835310141433838Mouse
1301382Arvm2_mautoimmune renal vasculitis 2 (mouse)Not determined4107791564141791756Mouse
10755522Hgb1_mhemoglobin 1 (mouse)4108477692142477692Mouse
10755521Hct1_mhematocrit 1 (mouse)4108477692142477692Mouse
10755520Rbc1_mred blood cell count 1 (mouse)4108477692142477692Mouse
1300839Dyscalc2_mdystrophic cardiac calcinosis 2 (mouse)Not determined4111009051145009280Mouse
1300743Skull6_mskull morphology 6 (mouse)Not determined4111009051145009280Mouse
15039385Mvlq3_mmacrovesicular liver lesion QTL 3 (mouse)4112182386146182386Mouse
4141001Tgq17_mtriglyceride QTL 17 (mouse)Not determined112523489146523489Mouse
10047132Albq19_malbuminuria QTL 19 (mouse)Not determined4112824389146824389Mouse
4142493Femwf13_mfemur work to failure 13 (mouse)Not determined116154678150154782Mouse
1302078Sluc21_msusceptibility to lung cancer 21 (mouse)Not determined4117401141151401275Mouse
14746982Manh56_mmandible shape 56 (mouse)4117815917151815917Mouse
1302102Bis1_mbeta-carboline-induced seizures 1 (mouse)Not determined4119864433153864536Mouse
1301964Bw8q2_mbody weight at 8 weeks QTL 2 (mouse)Not determined4119864433153864536Mouse
13503348Bntq18_mbone traits QTL 18 (mouse)4120617848154617995Mouse
10412210Cypr6_mcytokine production 6 (mouse)Not determined4120617848154617995Mouse
4141180Ssic1_msusceptibility to small intestinal cancer 1 (mouse)Not determined120674005154674151Mouse
1300803Sluc6_msusceptibility to lung cancer 6 (mouse)Not determined4120674005154674151Mouse
10043985Stheal12_msoft tissue heal 12 (mouse)Not determined4121342649155342753Mouse
4142061Chlq16_mcirculating hormone level QTL 16 (mouse)Not determined4121342649155342753Mouse
1301452Elsgp1_melevated serum gp70 1 (mouse)Not determined4121342649155342753Mouse
27226757Femd1_mfemur midshaft diameter 1, 5 week (mouse)4123993793144326570Mouse
4141065Shali2_msurvival time to hyperoxic acute lung injury 2 (mouse)Not determined124055093141572792Mouse
1300917Gasa1_mgastritis type A susceptibility locus 1 (mouse)Not determined4124055093142438020Mouse
1302149Tlsr2_mthymic lymphoma suppressor region 2 (mouse)Not determined4124264957142230960Mouse
1301525Lmb1_mlupus in MRL and B6 F2 cross (mouse)Not determined4124264957150676858Mouse
10755531Lymph3_mlymphocyte differential 3 (mouse)4124553483156860686Mouse
1300858Tafat_mtally ho associated mesenteric fat pad weight (mouse)Not determined4124621281156860686Mouse
4142139Adip12_madiposity 12 (mouse)Not determined4124621281156860686Mouse
1301982Pltiq1_mphospholipid transfer protein inducibility QTL 1 (mouse)Not determined4124621281156860686Mouse
1300933Cdcs9_mcytokine deficiency colitis susceptibility 9 (mouse)Not determined4125230872156860686Mouse
1300621Tpnr1_mthermal pain response 1 (mouse)Not determined4125230872156860686Mouse
10045620Heal22_mwound healing/regeneration 22 (mouse)Not determined4125230872156860686Mouse
11533916Mts1_mmammary tumor susceptibility 1 (mouse)4125289325156860686Mouse
10043996Gct5_mgranulosa cell tumorigenesis 5 (mouse)Not determined4127784226156860686Mouse
4142481Gct1_mgranulosa cell tumorigenesis 1 (mouse)Not determined4127784226156860686Mouse
1301584Lrdg2_mlight induced retinal degeneration 2 (mouse)Not determined4129465811151654550Mouse
1300874Gasa2_mgastritis type A susceptibility locus 2 (mouse)Not determined4133010494156860686Mouse
1301267Bcmd2_mB cell maturation defect 2 (mouse)Not determined4133154678150789451Mouse
4142077Ignpq2_mIgA nephropathy QTL 2 (mouse)Not determined4133676733156860686Mouse
1301108Scon2_msucrose consumption 2 (mouse)Not determined4134654451156860686Mouse
1300537Ap3q_malcohol preference 3 QTL (mouse)Not determined4134654451156860686Mouse
1357534Cinda3_mcytokine induced activation 3 (mouse)Not determined4137617848142289472Mouse
1300553Athsq1_matherosclerosis susceptibility QTL 1 (mouse)Not determined4137617848151654550Mouse
4141184Tb2r1_mTGF-beta2 responsiveness 1 (mouse)Not determined137674005150676858Mouse
1300780Cocrb16_mcocaine related behavior 16 (mouse)Not determined4138943725156860686Mouse

Markers in Region
Slc25a34  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4E1UniSTS
cM Map474.64UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000038661   ⟹   ENSMUSP00000039188
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4141,346,135 - 141,351,132 (-)Ensembl
GRCm38.p6 Ensembl4141,618,824 - 141,623,821 (-)Ensembl
RefSeq Acc Id: NM_001013780   ⟹   NP_001013802
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394141,346,135 - 141,351,145 (-)NCBI
GRCm384141,618,824 - 141,623,834 (-)NCBI
MGSCv374141,174,739 - 141,179,749 (-)RGD
Celera4143,441,650 - 143,447,213 (-)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006538996   ⟹   XP_006539059
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394141,346,130 - 141,351,202 (-)NCBI
GRCm384141,618,819 - 141,623,891 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001013802 (Get FASTA)   NCBI Sequence Viewer  
  XP_006539059 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein A2ADF7 (Get FASTA)   NCBI Sequence Viewer  
  AAH89627 (Get FASTA)   NCBI Sequence Viewer  
  EDL13389 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000039188
  ENSMUSP00000039188.8
RefSeq Acc Id: NP_001013802   ⟸   NM_001013780
- UniProtKB: Q5FW51 (UniProtKB/Swiss-Prot),   A2ADF7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006539059   ⟸   XM_006538996
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000039188   ⟸   ENSMUST00000038661

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A2ADF7-F1-model_v2 AlphaFold A2ADF7 1-318 view protein structure

Promoters
RGD ID:6836398
Promoter ID:MM_KWN:40501
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B6
Transcripts:ENSMUST00000038661,   UC008VOY.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364141,179,241 - 141,180,277 (-)MPROMDB
RGD ID:6885330
Promoter ID:EPDNEW_M6116
Type:initiation region
Name:Slc25a34_1
Description:Mus musculus solute carrier family 25, member 34 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384141,623,806 - 141,623,866EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2686215 AgrOrtholog
Ensembl Genes ENSMUSG00000040740 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000038661 ENTREZGENE
  ENSMUST00000038661.8 UniProtKB/Swiss-Prot
Gene3D-CATH 1.50.40.10 UniProtKB/Swiss-Prot
InterPro Mitochondrial_sb/sol_carrier UniProtKB/Swiss-Prot
  Mt_carrier_dom_sf UniProtKB/Swiss-Prot
KEGG Report mmu:384071 UniProtKB/Swiss-Prot
MGD MGI:2686215 ENTREZGENE
NCBI Gene 384071 ENTREZGENE
PANTHER RE38146P UniProtKB/Swiss-Prot
  SOLUTE CARRIER FAMILY 25 MEMBER 34 UniProtKB/Swiss-Prot
Pfam Mito_carr UniProtKB/Swiss-Prot
PhenoGen Slc25a34 PhenoGen
PROSITE SOLCAR UniProtKB/Swiss-Prot
Superfamily-SCOP SSF103506 UniProtKB/Swiss-Prot
UniProt A2ADF7 ENTREZGENE
  Q5FW51 ENTREZGENE
  S2534_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q5FW51 UniProtKB/Swiss-Prot