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Gene: Acly (ATP citrate lyase) Mus musculus
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Symbol: Acly
Name: ATP citrate lyase
Description: Exhibits ATP citrate synthase activity. Predicted to be involved in acetyl-CoA biosynthetic process and carboxylic acid metabolic process. Localizes to mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human ACLY (ATP citrate lyase); PARTICIPATES IN fatty acid biosynthetic pathway; citric acid cycle pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A730098H14Rik; ATP-citrate (pro-S-)-lyase; ATP-citrate synthase; AW538652; citrate cleavage enzyme
Orthologs:
Homo sapiens (human) : ACLY (ATP citrate lyase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Acly (ATP citrate lyase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acly (ATP citrate lyase)
Pan paniscus (bonobo/pygmy chimpanzee) : ACLY (ATP citrate lyase)
Canis lupus familiaris (dog) : ACLY (ATP citrate lyase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acly (ATP citrate lyase)
Sus scrofa (pig) : ACLY (ATP citrate lyase)
Chlorocebus sabaeus (African green monkey) : ACLY (ATP citrate lyase)
Heterocephalus glaber (naked mole-rat) : Acly (ATP citrate lyase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl11100,476,353 - 100,528,000 (-)EnsemblGRCm38mm10GRCm38
GRCm3811100,476,352 - 100,528,000 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3711100,337,670 - 100,389,215 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611100,292,446 - 100,343,991 (-)NCBImm8
Celera11111,095,710 - 111,147,350 (-)NCBICelera
Cytogenetic Map11DNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Acly
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10064
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-21
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.