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Gene: Acly (ATP citrate lyase) Mus musculus
Symbol: Acly
Name: ATP citrate lyase
Description: Exhibits ATP citrate synthase activity. Predicted to be involved in acetyl-CoA biosynthetic process and carboxylic acid metabolic process. Localizes to mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human ACLY (ATP citrate lyase); PARTICIPATES IN fatty acid biosynthetic pathway; citric acid cycle pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A730098H14Rik; ATP-citrate (pro-S-)-lyase; ATP-citrate synthase; AW538652; citrate cleavage enzyme
Homo sapiens (human) : ACLY (ATP citrate lyase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Acly (ATP citrate lyase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acly (ATP citrate lyase)
Pan paniscus (bonobo/pygmy chimpanzee) : ACLY (ATP citrate lyase)
Canis lupus familiaris (dog) : ACLY (ATP citrate lyase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acly (ATP citrate lyase)
Sus scrofa (pig) : ACLY (ATP citrate lyase)
Chlorocebus sabaeus (African green monkey) : ACLY (ATP citrate lyase)
Heterocephalus glaber (naked mole-rat) : Acly (ATP citrate lyase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl11100,476,353 - 100,528,000 (-)EnsemblGRCm38mm10GRCm38
GRCm3811100,476,352 - 100,528,000 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3711100,337,670 - 100,389,215 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611100,292,446 - 100,343,991 (-)NCBImm8
Celera11111,095,710 - 111,147,350 (-)NCBICelera
Cytogenetic Map11DNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Acly
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10064
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-21
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.