Brcc3 (BRCA1/BRCA2-containing complex, subunit 3) - Rat Genome Database

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Gene: Brcc3 (BRCA1/BRCA2-containing complex, subunit 3) Mus musculus
Analyze
Symbol: Brcc3
Name: BRCA1/BRCA2-containing complex, subunit 3
RGD ID: 1557359
MGI Page MGI
Description: Enables metal-dependent deubiquitinase activity. Involved in chromatin remodeling; positive regulation of NLRP3 inflammasome complex assembly; and protein K63-linked deubiquitination. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of BRCA1-A complex; BRISC complex; and nuclear ubiquitin ligase complex. Is expressed in central nervous system and genitourinary system. Orthologous to human BRCC3 (BRCA1/BRCA2-containing complex subunit 3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 6.1A protein; BRCA1-A complex subunit BRCC36; BRCA1/BRCA2-containing complex subunit 3; BRCA1/BRCA2-containing complex subunit 36; BRISC complex subunit BRCC36; C6.1; C6.1A; lys-63-specific deubiquitinase BRCC36; MGC29148
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm12598   Gm18884  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X74,460,234 - 74,499,307 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX74,460,234 - 74,497,607 (+)EnsemblGRCm39 Ensembl
GRCm38X75,416,628 - 75,455,702 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX75,416,628 - 75,454,001 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X72,661,967 - 72,701,040 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X71,669,420 - 71,706,717 (+)NCBIMGSCv36mm8
CeleraX66,818,616 - 66,858,058 (+)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX38.22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
BRCA1-A complex  (IBA,ISO,ISS,NAS)
BRISC complex  (IBA,ISO,ISS)
cytoplasm  (IEA,ISO)
nuclear ubiquitin ligase complex  (ISO)
nucleoplasm  (ISO)
nucleus  (ISO,ISS,NAS)
spindle pole  (IEA)
ubiquitin ligase complex  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. H2A-DUBbing the mammalian epigenome: expanding frontiers for histone H2A deubiquitinating enzymes in cell biology and physiology. Belle JI and Nijnik A, Int J Biochem Cell Biol. 2014 May;50:161-74. doi: 10.1016/j.biocel.2014.03.004. Epub 2014 Mar 16.
2. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. miR-3940-5p associated with genetic damage in workers exposed to hexavalent chromium. Li Y, etal., Toxicol Lett. 2014 Aug 17;229(1):319-26. doi: 10.1016/j.toxlet.2014.06.033. Epub 2014 Jun 25.
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. Push back to respond better: regulatory inhibition of the DNA double-strand break response. Panier S and Durocher D, Nat Rev Mol Cell Biol. 2013 Oct;14(10):661-72. doi: 10.1038/nrm3659. Epub 2013 Sep 4.
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Identification of genes differentially expressed in mouse fetuses from streptozotocin-induced diabetic pregnancy by cDNA subtraction. Sato N, etal., Endocr J. 2008 May;55(2):317-23. Epub 2008 Mar 7.
Additional References at PubMed
PMID:8247530   PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12485996   PMID:14610273   PMID:14636569   PMID:15489334   PMID:16141072   PMID:16141073  
PMID:18077395   PMID:18287559   PMID:20656689   PMID:21267068   PMID:21677750   PMID:21873635   PMID:22369660   PMID:22974638   PMID:23246432   PMID:23451117   PMID:26195665   PMID:28190767  
PMID:28943315   PMID:29459677   PMID:29676259   PMID:30755420   PMID:30787184   PMID:31485755   PMID:31787240   PMID:31866999   PMID:32325033   PMID:32554809   PMID:32941940   PMID:34180153  
PMID:34615873   PMID:34888627   PMID:35938958   PMID:36600050   PMID:37196079   PMID:37781816   PMID:37968261   PMID:38355793   PMID:38449391   PMID:38544474   PMID:38557054   PMID:39227917  


Genomics

Comparative Map Data
Brcc3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X74,460,234 - 74,499,307 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX74,460,234 - 74,497,607 (+)EnsemblGRCm39 Ensembl
GRCm38X75,416,628 - 75,455,702 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX75,416,628 - 75,454,001 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X72,661,967 - 72,701,040 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X71,669,420 - 71,706,717 (+)NCBIMGSCv36mm8
CeleraX66,818,616 - 66,858,058 (+)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX38.22NCBI
BRCC3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X155,071,508 - 155,123,077 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX155,071,420 - 155,123,077 (+)EnsemblGRCh38hg38GRCh38
GRCh37X154,299,783 - 154,351,352 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X153,952,904 - 154,004,543 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X153,863,504 - 153,915,052NCBI
CeleraX154,458,427 - 154,510,104 (+)NCBICelera
Cytogenetic MapXq28NCBI
HuRefX142,845,949 - 142,896,583 (+)NCBIHuRef
CHM1_1X154,211,322 - 154,263,032 (+)NCBICHM1_1
T2T-CHM13v2.0X153,307,916 - 153,359,479 (+)NCBIT2T-CHM13v2.0
Brcc3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr892,073,927 - 2,076,469 (+)NCBIGRCr8
mRatBN7.291,986,942 - 1,989,484 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl91,986,575 - 1,991,080 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx92,421,214 - 2,423,760 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.097,770,588 - 7,773,134 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.096,726,439 - 6,728,985 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.099,863,380 - 9,865,920 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl99,863,404 - 9,865,920 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.098,864,902 - 8,867,442 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera96,530,917 - 6,533,459 (-)NCBICelera
Cytogenetic Map9q11NCBI
Brcc3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955594554,081 - 613,661 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955594551,407 - 613,772 (-)NCBIChiLan1.0ChiLan1.0
BRCC3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X155,049,262 - 155,097,994 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X155,052,870 - 155,104,458 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X144,550,320 - 144,592,795 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X154,389,179 - 154,431,616 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX154,389,283 - 154,428,669 (+)Ensemblpanpan1.1panPan2
BRCC3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X123,081,262 - 123,143,509 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX123,081,050 - 123,140,133 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX108,074,648 - 108,136,853 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X126,208,828 - 126,271,057 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX126,173,490 - 126,271,057 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X121,956,711 - 122,018,913 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X124,479,132 - 124,541,327 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X124,199,851 - 124,262,068 (+)NCBIUU_Cfam_GSD_1.0
Brcc3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X119,982,639 - 120,022,107 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936927341,253 - 376,700 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936927341,114 - 380,817 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BRCC3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX125,383,414 - 125,439,082 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X125,383,392 - 125,439,082 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X142,991,891 - 143,046,729 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BRCC3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X129,358,759 - 129,406,293 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX129,358,862 - 129,403,352 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606567,336,845 - 67,385,677 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Brcc3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624963145,580 - 212,064 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624963142,987 - 212,190 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Brcc3
677 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2260
Count of miRNA genes:760
Interacting mature miRNAs:973
Transcripts:ENSMUST00000033544, ENSMUST00000114074, ENSMUST00000118428, ENSMUST00000124321, ENSMUST00000133781, ENSMUST00000151938, ENSMUST00000152228
Prediction methods:Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141630Gct6_mgranulosa cell tumorigenesis 6 (mouse)Not determined47179121129764756Mouse
13464140Hdlq108_mHDL QTL 108 (mouse)X5777196091771960Mouse
25314311Syncl3_msynaptonemal complex length 3 (mouse)X5198887789743606Mouse
13824980Ferq1_mgenetic fertility QTL 1 (mouse)X54045360148782996Mouse
4142200Rtwq1_mreduced testis weight QTL 1 (mouse)Not determined4147706075477203Mouse
1300794Spha2_msperm head anomaly 2 (mouse)Not determinedX3992149886260137Mouse
12879918Shm4_msperm head morphology 4 (mouse)X72072050102062720Mouse
25314318Sccor2_msynaptonemal complex length to mean MLH1 count ratio 2 (mouse)X7054360696543606Mouse
1357433Dbts2_mdiabetes 2 (mouse)Not determinedX7226295150107038Mouse
1301278Bdln1_mbody length 1 (mouse)Not determinedX4170210675702218Mouse
1300702Fcsa4_mfemoral cross-sectional area 4 (mouse)Not determinedX4602744480027567Mouse
25314316Mlh1fc3_mMLH1 foci count 3 (mouse)X6134360689843606Mouse
10412108Desp5_mdespair 5 (mouse)Not determinedX5472235188722351Mouse
1357730Hstx1_mhybrid sterility, X chromosome 1 (mouse)Not determinedX7145385277600812Mouse
13208567Bmiq12_mbody mass index QTL 12 (mouse)X3526365377043606Mouse
4141665Mhysq2_mmale hybrid sterility QTL 2 (mouse)Not determined71453852139203212Mouse

Markers in Region
px-70e7  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X75,423,166 - 75,423,271UniSTSGRCm38
MGSCv37X72,668,505 - 72,668,610UniSTSGRCm37
CeleraX66,825,154 - 66,825,259UniSTS
Cytogenetic MapXA7.3UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001166457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001166459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001358736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001358737 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_145956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC124025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK011876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK030736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK038919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK079866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL671860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC048179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD774860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S68022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000033544   ⟹   ENSMUSP00000033544
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX74,460,234 - 74,497,607 (+)Ensembl
GRCm38.p6 EnsemblX75,416,628 - 75,454,001 (+)Ensembl
Ensembl Acc Id: ENSMUST00000114074   ⟹   ENSMUSP00000109708
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX74,460,316 - 74,495,314 (+)Ensembl
GRCm38.p6 EnsemblX75,416,710 - 75,451,708 (+)Ensembl
Ensembl Acc Id: ENSMUST00000118428   ⟹   ENSMUSP00000114057
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX74,460,303 - 74,495,591 (+)Ensembl
GRCm38.p6 EnsemblX75,416,697 - 75,451,985 (+)Ensembl
Ensembl Acc Id: ENSMUST00000124321
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX74,477,584 - 74,494,830 (+)Ensembl
GRCm38.p6 EnsemblX75,433,978 - 75,451,224 (+)Ensembl
Ensembl Acc Id: ENSMUST00000133781   ⟹   ENSMUSP00000123031
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX74,460,322 - 74,481,597 (+)Ensembl
GRCm38.p6 EnsemblX75,416,716 - 75,437,991 (+)Ensembl
Ensembl Acc Id: ENSMUST00000151938
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX74,460,306 - 74,494,338 (+)Ensembl
GRCm38.p6 EnsemblX75,416,700 - 75,450,732 (+)Ensembl
Ensembl Acc Id: ENSMUST00000152228   ⟹   ENSMUSP00000127772
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX74,460,913 - 74,479,081 (+)Ensembl
GRCm38.p6 EnsemblX75,417,307 - 75,435,475 (+)Ensembl
RefSeq Acc Id: NM_001166457   ⟹   NP_001159929
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X74,460,234 - 74,497,607 (+)NCBI
GRCm38X75,416,628 - 75,454,001 (+)NCBI
MGSCv37X72,661,967 - 72,701,040 (+)RGD
CeleraX66,818,616 - 66,858,058 (+)RGD
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001166459   ⟹   NP_001159931
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X74,460,234 - 74,499,307 (+)NCBI
GRCm38X75,416,628 - 75,455,701 (+)NCBI
MGSCv37X72,661,967 - 72,701,040 (+)RGD
CeleraX66,818,616 - 66,858,058 (+)RGD
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001358736   ⟹   NP_001345665
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X74,460,234 - 74,499,307 (+)NCBI
GRCm38X75,416,628 - 75,455,701 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001358737   ⟹   NP_001345666
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X74,460,234 - 74,497,607 (+)NCBI
GRCm38X75,416,628 - 75,454,001 (+)NCBI
Sequence:
RefSeq Acc Id: NM_145956   ⟹   NP_666068
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X74,460,234 - 74,497,607 (+)NCBI
GRCm38X75,416,628 - 75,454,001 (+)NCBI
MGSCv37X72,661,967 - 72,701,040 (+)RGD
CeleraX66,818,616 - 66,858,058 (+)RGD
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: NP_666068   ⟸   NM_145956
- UniProtKB: Q3UDZ4 (UniProtKB/Swiss-Prot),   A8Y5K0 (UniProtKB/Swiss-Prot),   A3KGA9 (UniProtKB/Swiss-Prot),   Q9D025 (UniProtKB/Swiss-Prot),   P46737 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001159931   ⟸   NM_001166459
- UniProtKB: Q3UDZ4 (UniProtKB/Swiss-Prot),   A8Y5K0 (UniProtKB/Swiss-Prot),   A3KGA9 (UniProtKB/Swiss-Prot),   Q9D025 (UniProtKB/Swiss-Prot),   P46737 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001159929   ⟸   NM_001166457
- UniProtKB: Q3UDZ4 (UniProtKB/Swiss-Prot),   A8Y5K0 (UniProtKB/Swiss-Prot),   A3KGA9 (UniProtKB/Swiss-Prot),   Q9D025 (UniProtKB/Swiss-Prot),   P46737 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001345665   ⟸   NM_001358736
- UniProtKB: Q3UDZ4 (UniProtKB/Swiss-Prot),   P46737 (UniProtKB/Swiss-Prot),   A8Y5K0 (UniProtKB/Swiss-Prot),   A3KGA9 (UniProtKB/Swiss-Prot),   Q9D025 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001345666   ⟸   NM_001358737
- UniProtKB: Q3UDZ4 (UniProtKB/Swiss-Prot),   P46737 (UniProtKB/Swiss-Prot),   A8Y5K0 (UniProtKB/Swiss-Prot),   A3KGA9 (UniProtKB/Swiss-Prot),   Q9D025 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSMUSP00000114057   ⟸   ENSMUST00000118428
Ensembl Acc Id: ENSMUSP00000127772   ⟸   ENSMUST00000152228
Ensembl Acc Id: ENSMUSP00000033544   ⟸   ENSMUST00000033544
Ensembl Acc Id: ENSMUSP00000123031   ⟸   ENSMUST00000133781
Ensembl Acc Id: ENSMUSP00000109708   ⟸   ENSMUST00000114074
Protein Domains
MPN

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P46737-F1-model_v2 AlphaFold P46737 1-291 view protein structure

Promoters
RGD ID:6845537
Promoter ID:MM_KWN:60890
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000033544,   ENSMUST00000114074,   ENSMUST00000114081,   ENSMUST00000118428,   NM_001039373,   NM_001166459,   NM_145956,   OTTMUST00000049307,   OTTMUST00000049310,   OTTMUST00000049311,   OTTMUST00000049313,   OTTMUST00000049314,   OTTMUST00000049316,   OTTMUST00000054728,   OTTMUST00000072977
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X72,661,626 - 72,662,126 (+)MPROMDB
RGD ID:13680824
Promoter ID:EPDNEW_M24561
Type:multiple initiation site
Name:Brcc3_1
Description:Mus musculus BRCA1/BRCA2-containing complex, subunit 3 , transcriptvariant 5, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X75,416,700 - 75,416,760EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2389572 AgrOrtholog
Ensembl Genes ENSMUSG00000031201 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000033544 ENTREZGENE
  ENSMUST00000033544.14 UniProtKB/Swiss-Prot
  ENSMUST00000114074 ENTREZGENE
  ENSMUST00000114074.8 UniProtKB/Swiss-Prot
  ENSMUST00000118428.8 UniProtKB/Swiss-Prot
  ENSMUST00000133781.8 UniProtKB/TrEMBL
  ENSMUST00000152228.3 UniProtKB/TrEMBL
Gene3D-CATH Cytidine Deaminase, domain 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro BRCC36_C UniProtKB/Swiss-Prot
  JAMM/MPN+_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  JAMM_MPN+_peptidase_M67A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MPN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MPN_BRCC36 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:210766 UniProtKB/Swiss-Prot
MGD MGI:2389572 ENTREZGENE
NCBI Gene 210766 ENTREZGENE
PANTHER EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam BRCC36_C UniProtKB/Swiss-Prot
  JAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Brcc3 PhenoGen
PROSITE MPN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART JAB_MPN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP JAB1/MPN domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A3KGA8_MOUSE UniProtKB/TrEMBL
  A3KGA9 ENTREZGENE
  A8Y5K0 ENTREZGENE
  BRCC3_MOUSE UniProtKB/Swiss-Prot
  E9Q0P6_MOUSE UniProtKB/TrEMBL
  P46737 ENTREZGENE
  Q3UDZ4 ENTREZGENE
  Q9D025 ENTREZGENE
UniProt Secondary A3KGA9 UniProtKB/Swiss-Prot
  A8Y5K0 UniProtKB/Swiss-Prot
  Q3UDZ4 UniProtKB/Swiss-Prot
  Q9D025 UniProtKB/Swiss-Prot