BRCC3 (BRCA1/BRCA2-containing complex subunit 3)

Advanced Search (OLGA)

Gene: BRCC3 (BRCA1/BRCA2-containing complex subunit 3) Pan paniscus

Analyze

Symbol:

BRCC3

Name:

BRCA1/BRCA2-containing complex subunit 3

RGD ID:

11884338

Description:

ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); enzyme regulator activity (inferred); K63-linked deubiquitinase activity (inferred); INVOLVED IN chromatin remodeling (ortholog); response to X-ray (ortholog); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; ASSOCIATED WITH adrenoleukodystrophy (ortholog); autistic disorder (ortholog); autosomal hemophilia A (ortholog); FOUND IN nucleus (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

lys-63-specific deubiquitinase BRCC36

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	155,049,262 - 155,097,994 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	155,052,870 - 155,104,458 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	144,550,320 - 144,592,795 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	154,389,179 - 154,431,616 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	154,389,283 - 154,428,669 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

adrenoleukodystrophy (ISO)

autistic disorder (ISO)

autosomal hemophilia A (ISO)

Barth syndrome (ISO)

cerebral creatine deficiency syndrome 1 (ISO)

dyskeratosis congenita (ISO)

Emery-Dreifuss muscular dystrophy (ISO)

factor VIII deficiency (ISO)

favism (ISO)

Hereditary Neoplastic Syndromes (ISO)

immunodeficiency 33 (ISO)

Occupational Diseases (ISO)

paraplegia (ISO)

periventricular nodular heterotopia (ISO)

Pregnancy in Diabetics (ISO)

Splenomegaly (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell division (IEA)

cellular response to ionizing radiation (IEA)

chromatin remodeling (ISO)

DNA repair (IEA)

DNA repair-dependent chromatin remodeling (IEA)

double-strand break repair (IEA)

mitotic G2 DNA damage checkpoint signaling (IEA)

positive regulation of DNA repair (IEA)

positive regulation of NLRP3 inflammasome complex assembly (IEA)

protein K63-linked deubiquitination (IEA)

proteolysis (IEA)

response to ionizing radiation (IEA)

response to X-ray (IEA,ISO)

Cellular Component

BRCA1-A complex (IEA)

BRISC complex (IEA)

cytoplasm (IEA)

cytoskeleton (IEA)

nuclear ubiquitin ligase complex (IEA)

nucleoplasm (IEA)

nucleus (IEA,ISO)

spindle pole (IEA)

ubiquitin ligase complex (IEA)

Molecular Function

cysteine-type deubiquitinase activity (IEA)

enzyme regulator activity (IEA)

K63-linked deubiquitinase activity (IEA)

metal ion binding (IEA)

metal-dependent deubiquitinase activity (IEA)

metallopeptidase activity (IEA)

polyubiquitin modification-dependent protein binding (IEA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

ataxia telangiectasia-mutated (ATM) signaling pathway (ISO)

histone modification pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

BRCC3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	155,049,262 - 155,097,994 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	155,052,870 - 155,104,458 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	144,550,320 - 144,592,795 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	154,389,179 - 154,431,616 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	154,389,283 - 154,428,669 (+)	Ensembl	panpan1.1		panPan2

BRCC3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	155,071,508 - 155,123,077 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	155,071,420 - 155,123,077 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	154,299,783 - 154,351,352 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	153,952,904 - 154,004,543 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	153,863,504 - 153,915,052	NCBI
Celera	X	154,458,427 - 154,510,104 (+)	NCBI		Celera
Cytogenetic Map	X	q28	NCBI
HuRef	X	142,845,949 - 142,896,583 (+)	NCBI		HuRef
CHM1_1	X	154,211,322 - 154,263,032 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	153,307,916 - 153,359,479 (+)	NCBI		T2T-CHM13v2.0

Brcc3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	74,460,234 - 74,499,307 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	74,460,234 - 74,497,607 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	75,416,628 - 75,455,702 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	75,416,628 - 75,454,001 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	72,661,967 - 72,701,040 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	71,669,420 - 71,706,717 (+)	NCBI		MGSCv36	mm8
Celera	X	66,818,616 - 66,858,058 (+)	NCBI		Celera
Cytogenetic Map	X	A7.3	NCBI
cM Map	X	38.22	NCBI

Brcc3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	2,073,927 - 2,076,469 (+)	NCBI		GRCr8
mRatBN7.2	9	1,986,942 - 1,989,484 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	1,986,575 - 1,991,080 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	2,421,214 - 2,423,760 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	7,770,588 - 7,773,134 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	6,726,439 - 6,728,985 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	9,863,380 - 9,865,920 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	9,863,404 - 9,865,920 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	8,864,902 - 8,867,442 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	9	6,530,917 - 6,533,459 (-)	NCBI		Celera
Cytogenetic Map	9	q11	NCBI

Brcc3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955594	554,081 - 613,661 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955594	551,407 - 613,772 (-)	NCBI	ChiLan1.0	ChiLan1.0

BRCC3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	123,081,262 - 123,143,509 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	123,081,050 - 123,140,133 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	108,074,648 - 108,136,853 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	126,208,828 - 126,271,057 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	126,173,490 - 126,271,057 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	121,956,711 - 122,018,913 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	124,479,132 - 124,541,327 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	124,199,851 - 124,262,068 (+)	NCBI		UU_Cfam_GSD_1.0

Brcc3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	119,982,639 - 120,022,107 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936927	341,253 - 376,700 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936927	341,114 - 380,817 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

BRCC3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	125,383,414 - 125,439,082 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	125,383,392 - 125,439,082 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	142,991,891 - 143,046,729 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

BRCC3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	129,358,759 - 129,406,293 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	129,358,862 - 129,403,352 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666065	67,336,845 - 67,385,677 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Brcc3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624963	145,580 - 212,064 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624963	142,987 - 212,190 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003809952	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003809953	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008962323	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008962324	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008962325	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008962326	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008962328	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008962329	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_024927246	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055106759	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_057301166	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_057301167	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_057301168	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063601715	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000057016 ⟹ ENSPPAP00000034135

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	X	154,389,283 - 154,428,669 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000057023 ⟹ ENSPPAP00000034142

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	X	154,389,283 - 154,428,669 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000057028 ⟹ ENSPPAP00000034147

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	X	154,389,283 - 154,428,669 (+)	Ensembl

RefSeq Acc Id:

XM_008962324 ⟹ XP_008960572

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	X	155,049,265 - 155,089,645 (+)	NCBI
NHGRI_mPanPan1	X	155,052,873 - 155,093,253 (+)	NCBI
Mhudiblu_PPA_v0	X	144,550,325 - 144,590,551 (+)	NCBI
PanPan1.1	X	154,389,181 - 154,429,374 (+)	NCBI

Sequence:

show sequence

GGGCGGAGCGCACAGCGCTGGGCGCTGAGGAGGCTGCGCCGCAGCACCCGGTTGGTCAGGACCA
AGTGGGCCCGAGGCGGACGTGAGAAGGGTCGGGCCAAGATGGCGGTGCAGGTGGTGCAGGCGGT
GCAGGCGGTTCATCTCGAGTCTGACGCTTTCCTCGTTTGTCTCAACCACGCTCTGAGCACAGAG
AAGGAGGAAGTAATGGGGCTGTGCATAGGGGAGTTGAACGATGATACAAGTAGGAGTGACTCCA
AATTTGCATATACTGGAACTGAAATGCGCACAGTTGCTGAAAAGGTTGATGCCGTCAGAATTGT
TCACATTCATTCTGTCATCATCTTACGACGTTCTGATAAGAGGAAGGACCGAGTAGAAATTTCT
CCAGAGCAGCTGTCTGCAGCTTCAACAGAGGCAGAGAGGTTGGCTGAACTGACAGGCCGCCCCA
TGAGAGTTGTGGGCTGGTATCATTCCCACCCTCATATAACTGTTTGGCCTTCACATGTTGATGT
TCGCACACAAGCCATGTACCAGATGATGGATCAAGGCTTTGTAGGACTTATTTTTTCCTGTTTC
ATAGAAGATAAGAACACAAAGACTGGCCGGGTACTCTACACTTGCTTCCAATCCATACAGGCCC
AAAAGAGTTCAGAGTCCCTTCATGGTCCACGAGACTTCTGGAGCTCCAGCCAGCACATCTCCAT
TGAGGGCCAGAAGGAAGAGGAAAGGTATGAGAGAATCGAAATCCCAATCCATATTGTACCTCAT
GTCACTATCGGGAAAGTGTGCCTTGAATCAGCAGTAGAGCTGCCCAAGATCCTGTGCCAGGAGG
AGCAGGATGCGTATAGGAGGATCCACAGCCTTACACATCTGGACTCAGTAACCAAGATCCATAA
TGGCTCAGTGTTTACCAAGAATCTGTGCAGTCAGATGTCGGCAATCAGCGGGCCTCTCCTACAG
TGGTTGGAGGACAGACTGGAGCAAAACCAACAGCATTTGCAGGAATTACAACAAGAAAAGGAAG
AGCTTATGCAAGAACTTTCTTCTCTAGAATAAATCAGCAGACAAAATGGGGTATGATGCTTATG
TTGGACAAGCAAATAATAAATCCAGTGTGAGTGGAAGGAAGTACCCCACCTCTATGCCCTCATT
GAGAGGACAGTGTCTTCCTTCTTGATTTCTAAAATATATGTTCTGAGATACCTATCAAACATTG
AATCTCTGAGGGTGCCCTTTTTAGCCAAACATGAGTTCTAGCATATTTGACTCTGAAGTAAATT
CCTATTGAGCAGATCCTATCTGCCTAGGAGTTTCCATTATAGTAAAATGTGTTTCTCCAGAAAC
ATTTAGGATTGAGGATATAATAAAAATCATGCTTTAAAAA

hide sequence

RefSeq Acc Id:

XM_008962325 ⟹ XP_008960573

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	X	155,049,265 - 155,097,994 (+)	NCBI
NHGRI_mPanPan1	X	155,052,873 - 155,104,458 (+)	NCBI
Mhudiblu_PPA_v0	X	144,550,325 - 144,591,688 (+)	NCBI
PanPan1.1	X	154,389,181 - 154,430,462 (+)	NCBI

Sequence:

show sequence

GGGCGGAGCGCACAGCGCTGGGCGCTGAGGAGGCTGCGCCGCAGCACCCGGTTGGTCAGGACCA
AGTGGGCCCGAGGCGGACGTGAGAAGGGTCGGGCCAAGATGGCGGTGCAGGTGGTGCAGGCGGT
GCAGGCGGTTCATCTCGAGTCTGACGCTTTCCTCGTTTGTCTCAACCACGCTCTGAGCACAGAG
AAGGAGGAAGTAATGGGGCTGTGCATAGGGGAGTTGAACGATGATACAAGTAGGAGTGACTCCA
AATTTGCATATACTGGAACTGAAATGCGCACAGTTGCTGAAAAGGTTGATGCCGTCAGAATTGT
TCACATTCATTCTGTCATCATCTTACGACGTTCTGATAAGAGGAAGGACCGAGTAGAAATTTCT
CCAGAGCAGCTGTCTGCAGCTTCAACAGAGGCAGAGAGGTTGGCTGAACTGACAGGCCGCCCCA
TGAGAGTTGTGGGCTGGTATCATTCCCACCCTCATATAACTGTTTGGCCTTCACATGTTGATGT
TCGCACACAAGCCATGTACCAGATGATGGATCAAGGCTTTGTAGGACTTATTTTTTCCTGTTTC
ATAGAAGATAAGAACACAAAGACTGGCCGGGTACTCTACACTTGCTTCCAATCCATACAGGCCC
AAAAGAGTTCAGAGTCCCTTCATGGTCCACGAGACTTCTGGAGCTCCAGCCAGCACATCTCCAT
TGAGGGCCAGAAGGAAGAGGAAAGGTATGAGAGAATCGAAATCCCAATCCATATTGTACCTCAT
GTCACTATCGGGAAAGTGTGCCTTGAATCAGCAGTAGAGCTGCCCAAGATCCTGTGCCAGGAGG
AGCAGGATGCGTATAGGAGGATCCACAGCCTTACACATCTGGACTCAGTAACCAAGATCCATAA
TGGCTCAGTGTTTACCAAGAATCTGTGCAGTCAGATGTCGGCAATCAGCGGGCCTCTCCTACAG
TGGTTGGAGGACAGACTGGAGCAAAACCAACAGCATTTGCAGGAATTACAACAAGAAAAGGAAG
AGCTTATGCAAGAACTTTCTTCTCTAGAATAAATCAGCAGACAAAATGGGGAAAGATGAAAATA
TCCAGTGTAAAGTTACTTAAGCTAAATCAATTTCGAAGAAGAAAAACTTGGAGGACTCATTTTA
CCTGACTTCAAGACTTACTATAAAGCTATAGTAATCAAGATAGATGGTATTGGCAGAGGAACAG
ACACATACGTCAATGGAACAGATGAGAGAACCCAGAAATAAACCCATATAAATATGCTCAGCTG
ATTTTGAAAAAGTGCAAAAGCAATTCAATGGAGGAAGAATAGCCTTTCTGACAAATTATGCTAG
AGCAATTAGACACCCATGGCGAGGAGAAAAAAGAACCTCTACTTAAACCTCACATCTTATATAA
AATTTAACTCAAAATGTATAACGGACTTAAATGTGATACATAAAACTATATAACTTTGAAAAAA
GCCACAGGAGAAAAATCTTCAGGATCTTGGGCTAGGTGACAAGTTCTTGGACTTTGCCCCAAAA
GCACATCCATAAAAGACAAAATCTGATATATTGGACTTCTTCAAAATTTAAAAACTTGTGATTT
AAGAAGAGGAAAAGATAAGCTACAGATTGAGATGAATTTGCAAACCATATATCTGATTAATTTG
GAATATATAAAGTGTACTAAAAACTCAACTGAAGTCAGGCATGGTAGCTCATGCTTGTAATCTC
ACCACTTTGGAAGGCCAAGATGGGAGGAGTGCTTGAGGTTA

hide sequence

RefSeq Acc Id:

XM_008962326 ⟹ XP_008960574

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	X	155,049,262 - 155,095,129 (+)	NCBI
NHGRI_mPanPan1	X	155,052,870 - 155,093,253 (+)	NCBI
Mhudiblu_PPA_v0	X	144,550,323 - 144,590,551 (+)	NCBI
PanPan1.1	X	154,389,180 - 154,429,374 (+)	NCBI

Sequence:

show sequence

TGGGCGGAGCGCACAGCGCTGGGCGCTGAGGAGGCTGCGCCGCAGCACCCGGTTGGTCAGGACC
AAGTGGGCCCGAGGCGGACGTGAGAAGGGTCGGGCCAAGATGGCGGTGCAGGTGGTGCAGGCGG
TGCAGGCGGTTCATCTCGAGTCTGACGCTTTCCTCGTTTGTCTCAACCACGCTCTGAGCACAGA
GAAGGAGGAAGTAATGGGGCTGTGCATAGGGGAGTTGAACGATGATACAAGGAGTGACTCCAAA
TTTGCATATACTGGAACTGAAATGCGCACAGTTGCTGAAAAGGTTGATGCCGTCAGAATTGTTC
ACATTCATTCTGTCATCATCTTACGACGTTCTGATAAGAGGAAGGACCGAGTAGAAATTTCTCC
AGAGCAGCTGTCTGCAGCTTCAACAGAGGCAGAGAGGTTGGCTGAACTGACAGGCCGCCCCATG
AGAGTTGTGGGCTGGTATCATTCCCACCCTCATATAACTGTTTGGCCTTCACATGTTGATGTTC
GCACACAAGCCATGTACCAGATGATGGATCAAGGCTTTGTAGGACTTATTTTTTCCTGTTTCAT
AGAAGATAAGAACACAAAGACTGGCCGGGTACTCTACACTTGCTTCCAATCCATACAGGCCCAA
AAGAGTTCAGAGTCCCTTCATGGTCCACGAGACTTCTGGAGCTCCAGCCAGCACATCTCCATTG
AGGGCCAGAAGGAAGAGGAAAGGTATGAGAGAATCGAAATCCCAATCCATATTGTACCTCATGT
CACTATCGGGAAAGTGTGCCTTGAATCAGCAGTAGAGCTGCCCAAGATCCTGTGCCAGGAGGAG
CAGGATGCGTATAGGAGGATCCACAGCCTTACACATCTGGACTCAGTAACCAAGATCCATAATG
GCTCAGTGTTTACCAAGAATCTGTGCAGTCAGATGTCGGCAATCAGCGGGCCTCTCCTACAGTG
GTTGGAGGACAGACTGGAGCAAAACCAACAGCATTTGCAGGAATTACAACAAGAAAAGGAAGAG
CTTATGCAAGAACTTTCTTCTCTAGAATAAATCAGCAGACAAAATGGGGTACAAAACTTCTTTT
TCAGTTTGTGTACTAAACACAGTCTGAAAATGCACACAGCTCACATGCAGGCAGACAATAGAGT
AGTTATTTTTCACATGCAATCAGCACAGGATGTCTTCTTGACAGTTTAATTAGAGTTCACTGAA
CCCTCCTACCTATAACTGACCAATAAGGAGCTTATGCAAGATGATTTAAGTAGAATATGGAAGT
TATTTTTAAAAAGGCTATGGGTGGTACAATGGCAAGGAATATCTTAGAATAAAATGTCTGGGGA
GTATATTTTAAACATTTATATTTCCCTTTCTTTTAACTTGGAAGTCTTTATTTTCATTTTCAAA
TACATTCACTCACTAGAGTATTTTATGTTTCAATTTTGTAGGTATGATGCTTATGTTGGACAAG
CAAATAATAAATCCAGTGTGAGTGGAAGGAAGTACCCCACCTCTATGCCCTCATTGAGAGGACA
GTGTCTTCCTTCTTGATTTCTAAAATATATGTTCTGAGATACCTATCAAACATTGAATCTCTGA
GGGTGCCCTTTTTAGCCAAACATGAGTTCTAGCATATTTGACTCTGAAGTAAATTCCTATTGAG
CAGATCCTATCTGCCTAGGAGTTTCCATTATAGTAAAATGTGTTTCTCCAGAAACATTTAGGAT
TGAGGATATAATAAAAATCATGCTTTAAAAA

hide sequence

RefSeq Acc Id:

XM_008962328 ⟹ XP_008960576

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	X	155,049,267 - 155,095,129 (+)	NCBI
NHGRI_mPanPan1	X	155,052,876 - 155,093,253 (+)	NCBI
Mhudiblu_PPA_v0	X	144,550,451 - 144,590,551 (+)	NCBI
PanPan1.1	X	154,389,181 - 154,429,374 (+)	NCBI

Sequence:

show sequence

GGGCGGAGCGCACAGCGCTGGGCGCTGAGGAGGCTGCGCCGCAGCACCCGGTTGGTCAGGACCA
AGTGGGCCCGAGGCGGACGTGAGAAGGGTCGGGCCAAGATGGCGGTGCAGGTGGTGCAGGCGGT
GCAGGCGGTTCATCTCGAGTCTGACGCTTTCCTCGTTTGTCTCAACCACGCTCTGAGCACAGAG
AAGGAGGAAGTAATGGGGCTGTGCATAGGGGAGTTGAACGATGATACAAGGAGTGACTCCAAAT
TTGCATATACTGGAACTGAAATGCGCACAGTTGCTGAAAAGGTTGATGCCGTCAGAATTGTTCA
CATTCATTCTGTCATCATCTTACGACGTTCTGATAAGAGGAAGGACCGAGTAGAAATTTCTCCA
GAGCAGCTGTCTGCAGCTTCAACAGAGGCAGAGAGGTTGGCTGAACTGACAGGCCGCCCCATGA
GAGTTGTGGGCTGGTATCATTCCCACCCTCATATAACTGTTTGGCCTTCACATGTTGATGTTCG
CACACAAGCCATGTACCAGATGATGGATCAAGGCTTTGTAGGACTTATTTTTTCCTGTTTCATA
GAAGATAAGAACACAAAGACTGGCCGGGTACTCTACACTTGCTTCCAATCCATACAGGCCCAAA
AGAGTTCAGAGTATGAGAGAATCGAAATCCCAATCCATATTGTACCTCATGTCACTATCGGGAA
AGTGTGCCTTGAATCAGCAGTAGAGCTGCCCAAGATCCTGTGCCAGGAGGAGCAGGATGCGTAT
AGGAGGATCCACAGCCTTACACATCTGGACTCAGTAACCAAGATCCATAATGGCTCAGTGTTTA
CCAAGAATCTGTGCAGTCAGATGTCGGCAATCAGCGGGCCTCTCCTACAGTGGTTGGAGGACAG
ACTGGAGCAAAACCAACAGCATTTGCAGGAATTACAACAAGAAAAGGAAGAGCTTATGCAAGAA
CTTTCTTCTCTAGAATAAATCAGCAGACAAAATGGGGTACAAAACTTCTTTTTCAGTTTGTGTA
CTAAACACAGTCTGAAAATGCACACAGCTCACATGCAGGCAGACAATAGAGTAGTTATTTTTCA
CATGCAATCAGCACAGGATGTCTTCTTGACAGTTTAATTAGAGTTCACTGAACCCTCCTACCTA
TAACTGACCAATAAGGAGCTTATGCAAGATGATTTAAGTAGAATATGGAAGTTATTTTTAAAAA
GGCTATGGGTGGTACAATGGCAAGGAATATCTTAGAATAAAATGTCTGGGGAGTATATTTTAAA
CATTTATATTTCCCTTTCTTTTAACTTGGAAGTCTTTATTTTCATTTTCAAATACATTCACTCA
CTAGAGTATTTTATGTTTCAATTTTGTAGGTATGATGCTTATGTTGGACAAGCAAATAATAAAT
CCAGTGTGAGTGGAAGGAAGTACCCCACCTCTATGCCCTCATTGAGAGGACAGTGTCTTCCTTC
TTGATTTCTAAAATATATGTTCTGAGATACCTATCAAACATTGAATCTCTGAGGGTGCCCTTTT
TAGCCAAACATGAGTTCTAGCATATTTGACTCTGAAGTAAATTCCTATTGAGCAGATCCTATCT
GCCTAGGAGTTTCCATTATAGTAAAATGTGTTTCTCCAGAAACATTTAGGATTGAGGATATAAT
AAAAATCATGCTTTAAAAA

hide sequence

RefSeq Acc Id:

XM_024927246 ⟹ XP_024783014

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	X	155,049,265 - 155,095,129 (+)	NCBI
NHGRI_mPanPan1	X	155,052,873 - 155,093,253 (+)	NCBI
Mhudiblu_PPA_v0	X	144,550,328 - 144,590,551 (+)	NCBI
PanPan1.1	X	154,389,181 - 154,429,374 (+)	NCBI

Sequence:

show sequence

GGGCGGAGCGCACAGCGCTGGGCGCTGAGGAGGCTGCGCCGCAGCACCCGGTTGGTCAGGACCA
AGTGGGCCCGAGGCGGACGTGAGAAGGGTCGGGCCAAGATGGCGGTGCAGGTGGTGCAGGCGGT
GCAGGCGGTTCATCTCGAGTCTGACGCTTTCCTCGTTTGTCTCAACCACGCTCTGAGCACAGAG
AAGGAGGAAGTAATGGGGCTGTGCATAGGGGAGTTGAACGATGATACAAGGAGTGACTCCAAAT
TTGCATATACTGGAACTGAAATGCGCACAGTTGCTGAAAAGGTTGATGCCGTCAGAATTGTTCA
CATTCATTCTGTCATCATCTTACGACGTTCTGATAAGAGGAAGGACCGAGTAGAAATTTCTCCA
GAGCAGCTGTCTGCAGCTTCAACAGAGGCAGAGAGGTTGGCTGAACTGACAGGCCGCCCCATGA
GAGTTGTGGGCTGGTATCATTCCCACCCTCATATAACTGTTTGGCCTTCACATGTTGATGTTCG
CACACAAGCCATGTACCAGATGATGGATCAAGGCTTTGTAGGACTTATTTTTTCCTGTTTCATA
GAAGATAAGAACACAAAGACTGGCCGGGTACTCTACACTTGCTTCCAATCCATACAGGCCCAAA
AGAGTTCAGACCTTACACATCTGGACTCAGTAACCAAGATCCATAATGGCTCAGTGTTTACCAA
GAATCTGTGCAGTCAGATGTCGGCAATCAGCGGGCCTCTCCTACAGTGGTTGGAGGACAGACTG
GAGCAAAACCAACAGCATTTGCAGGAATTACAACAAGAAAAGGAAGAGCTTATGCAAGAACTTT
CTTCTCTAGAATAAATCAGCAGACAAAATGGGGTACAAAACTTCTTTTTCAGTTTGTGTACTAA
ACACAGTCTGAAAATGCACACAGCTCACATGCAGGCAGACAATAGAGTAGTTATTTTTCACATG
CAATCAGCACAGGATGTCTTCTTGACAGTTTAATTAGAGTTCACTGAACCCTCCTACCTATAAC
TGACCAATAAGGAGCTTATGCAAGATGATTTAAGTAGAATATGGAAGTTATTTTTAAAAAGGCT
ATGGGTGGTACAATGGCAAGGAATATCTTAGAATAAAATGTCTGGGGAGTATATTTTAAACATT
TATATTTCCCTTTCTTTTAACTTGGAAGTCTTTATTTTCATTTTCAAATACATTCACTCACTAG
AGTATTTTATGTTTCAATTTTGTAGGTATGATGCTTATGTTGGACAAGCAAATAATAAATCCAG
TGTGAGTGGAAGGAAGTACCCCACCTCTATGCCCTCATTGAGAGGACAGTGTCTTCCTTCTTGA
TTTCTAAAATATATGTTCTGAGATACCTATCAAACATTGAATCTCTGAGGGTGCCCTTTTTAGC
CAAACATGAGTTCTAGCATATTTGACTCTGAAGTAAATTCCTATTGAGCAGATCCTATCTGCCT
AGGAGTTTCCATTATAGTAAAATGTGTTTCTCCAGAAACATTTAGGATTGAGGATATAATAAAA
ATCATGCTTTAAAAA

hide sequence

RefSeq Acc Id:

XM_055106759 ⟹ XP_054962734

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	X	155,049,266 - 155,089,645 (+)	NCBI
NHGRI_mPanPan1	X	155,052,875 - 155,093,253 (+)	NCBI

RefSeq Acc Id:

XM_057301166 ⟹ XP_057157149

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	X	155,049,265 - 155,097,994 (+)	NCBI
NHGRI_mPanPan1	X	155,052,873 - 155,104,458 (+)	NCBI

RefSeq Acc Id:

XM_057301167 ⟹ XP_057157150

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	X	155,049,266 - 155,097,994 (+)	NCBI
NHGRI_mPanPan1	X	155,052,875 - 155,104,456 (+)	NCBI

RefSeq Acc Id:

XM_057301168 ⟹ XP_057157151

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	X	155,049,266 - 155,097,994 (+)	NCBI
NHGRI_mPanPan1	X	155,052,875 - 155,104,456 (+)	NCBI

RefSeq Acc Id:

XM_063601715 ⟹ XP_063457785

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	X	155,049,267 - 155,095,129 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_008960572	(Get FASTA)	NCBI Sequence Viewer
	XP_008960573	(Get FASTA)	NCBI Sequence Viewer
	XP_008960574	(Get FASTA)	NCBI Sequence Viewer
	XP_008960576	(Get FASTA)	NCBI Sequence Viewer
	XP_024783014	(Get FASTA)	NCBI Sequence Viewer
	XP_054962734	(Get FASTA)	NCBI Sequence Viewer
	XP_057157149	(Get FASTA)	NCBI Sequence Viewer
	XP_057157150	(Get FASTA)	NCBI Sequence Viewer
	XP_057157151	(Get FASTA)	NCBI Sequence Viewer
	XP_063457785	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000034135
	ENSPPAP00000034135.1
	ENSPPAP00000034142.1
	ENSPPAP00000034147
	ENSPPAP00000034147.1

RefSeq Acc Id:	XP_008960574 ⟸ XM_008962326
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R9C065 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAVQVVQAVQAVHLESDAFLVCLNHALSTEKEEVMGLCIGELNDDTRSDSKFAYTGTEMRTVAE KVDAVRIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAERLAELTGRPMRVVGWYHSHPHIT VWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQSIQAQKSSESLHGPRDFW SSSQHISIEGQKEEERYERIEIPIHIVPHVTIGKVCLESAVELPKILCQEEQDAYRRIHSLTHL DSVTKIHNGSVFTKNLCSQMSAISGPLLQWLEDRLEQNQQHLQELQQEKEELMQELSSLE hide sequence

RefSeq Acc Id:	XP_008960573 ⟸ XM_008962325
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9C065 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAVQVVQAVQAVHLESDAFLVCLNHALSTEKEEVMGLCIGELNDDTSRSDSKFAYTGTEMRTVA EKVDAVRIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAERLAELTGRPMRVVGWYHSHPHI TVWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQSIQAQKSSESLHGPRDF WSSSQHISIEGQKEEERYERIEIPIHIVPHVTIGKVCLESAVELPKILCQEEQDAYRRIHSLTH LDSVTKIHNGSVFTKNLCSQMSAISGPLLQWLEDRLEQNQQHLQELQQEKEELMQELSSLE hide sequence

RefSeq Acc Id:	XP_008960572 ⟸ XM_008962324
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9C065 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAVQVVQAVQAVHLESDAFLVCLNHALSTEKEEVMGLCIGELNDDTSRSDSKFAYTGTEMRTVA EKVDAVRIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAERLAELTGRPMRVVGWYHSHPHI TVWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQSIQAQKSSESLHGPRDF WSSSQHISIEGQKEEERYERIEIPIHIVPHVTIGKVCLESAVELPKILCQEEQDAYRRIHSLTH LDSVTKIHNGSVFTKNLCSQMSAISGPLLQWLEDRLEQNQQHLQELQQEKEELMQELSSLE hide sequence

RefSeq Acc Id:	XP_008960576 ⟸ XM_008962328
- Peptide Label:	isoform X4
- UniProtKB:	A0A2R9BWT4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAVQVVQAVQAVHLESDAFLVCLNHALSTEKEEVMGLCIGELNDDTRSDSKFAYTGTEMRTVAE KVDAVRIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAERLAELTGRPMRVVGWYHSHPHIT VWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQSIQAQKSSEYERIEIPIH IVPHVTIGKVCLESAVELPKILCQEEQDAYRRIHSLTHLDSVTKIHNGSVFTKNLCSQMSAISG PLLQWLEDRLEQNQQHLQELQQEKEELMQELSSLE hide sequence

RefSeq Acc Id:	XP_024783014 ⟸ XM_024927246
- Peptide Label:	isoform X5
- UniProtKB:	A0A2R9BWT8 (UniProtKB/TrEMBL), A0A2R9BWT4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAVQVVQAVQAVHLESDAFLVCLNHALSTEKEEVMGLCIGELNDDTRSDSKFAYTGTEMRTVAE KVDAVRIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAERLAELTGRPMRVVGWYHSHPHIT VWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQSIQAQKSSDLTHLDSVTK IHNGSVFTKNLCSQMSAISGPLLQWLEDRLEQNQQHLQELQQEKEELMQELSSLE hide sequence

Ensembl Acc Id:

ENSPPAP00000034135 ⟸ ENSPPAT00000057016

Ensembl Acc Id:

ENSPPAP00000034142 ⟸ ENSPPAT00000057023

Ensembl Acc Id:

ENSPPAP00000034147 ⟸ ENSPPAT00000057028

RefSeq Acc Id:	XP_054962734 ⟸ XM_055106759
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_057157149 ⟸ XM_057301166
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_057157150 ⟸ XM_057301167
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_057157151 ⟸ XM_057301168
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_063457785 ⟸ XM_063601715
- Peptide Label:	isoform X3

Protein Domains

MPN

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000039895	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000057016.1	UniProtKB/TrEMBL
	ENSPPAT00000057023.1	UniProtKB/TrEMBL
	ENSPPAT00000057028.1	UniProtKB/TrEMBL
Gene3D-CATH	Cytidine Deaminase, domain 2	UniProtKB/TrEMBL
InterPro	BRCC36_C	UniProtKB/TrEMBL
	JAMM/MPN+_dom	UniProtKB/TrEMBL
	JAMM_MPN+_peptidase_M67A	UniProtKB/TrEMBL
	MPN	UniProtKB/TrEMBL
	MPN_BRCC36	UniProtKB/TrEMBL
NCBI Gene	BRCC3	ENTREZGENE
PANTHER	EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED	UniProtKB/TrEMBL
	LYS-63-SPECIFIC DEUBIQUITINASE BRCC36	UniProtKB/TrEMBL
	LYS-63-SPECIFIC DEUBIQUITINASE BRCC36-RELATED	UniProtKB/TrEMBL
Pfam	BRCC36_C	UniProtKB/TrEMBL
	JAB	UniProtKB/TrEMBL
PROSITE	MPN	UniProtKB/TrEMBL
SMART	JAB_MPN	UniProtKB/TrEMBL
Superfamily-SCOP	JAB1/MPN domain	UniProtKB/TrEMBL
UniProt	A0A2R9BWT4	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9BWT8	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9C065	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

RGD Manual Annotations

Send us a Message

Imported Disease Annotations - ClinVar

RGD Manual Annotations