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Gene: Nfatc4 (nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4) Mus musculus
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Symbol: Nfatc4
Name: nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and transcription factor binding activity. Involved in several processes, including intracellular signal transduction; negative regulation of nervous system development; and regulation of transcription by RNA polymerase II. Localizes to the cytosol; nucleus; and transcription factor complex. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human NFATC4 (nuclear factor of activated T cells 4); PARTICIPATES IN calcineurin signaling pathway; nuclear factor of activated T-cells signaling pathway; B cell receptor signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3110041H08Rik; AW107667; AW546455; NF-AT3; NF-ATc4; Nfat3; nuclear factor of activated T-cells, cytoplasmic 4; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4; T-cell transcription factor NFAT3; transcription complex subunit NF-ATc4
Orthologs:
Homo sapiens (human) : NFATC4 (nuclear factor of activated T cells 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nfatc4 (nuclear factor of activated T-cells 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfatc4 (nuclear factor of activated T cells 4)
Pan paniscus (bonobo/pygmy chimpanzee) : NFATC4 (nuclear factor of activated T cells 4)
Canis lupus familiaris (dog) : NFATC4 (nuclear factor of activated T cells 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfatc4 (nuclear factor of activated T cells 4)
Sus scrofa (pig) : NFATC4 (nuclear factor of activated T cells 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381455,824,795 - 55,833,943 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371456,443,632 - 56,452,780 (+)NCBIGRCm37mm9NCBIm37
MGSCv361454,779,079 - 54,788,014 (+)NCBImm8
Celera1453,626,552 - 53,635,649 (+)NCBICelera
Cytogenetic Map14 C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Annotation    (Toggle Annotation Detail/Summary View)

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Genomics

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Sequence

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Nomenclature History
  
More on Nfatc4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
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RGD Object Information
RGD ID: 1321837
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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