GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Srebf1 | increases expression | EXP | | 6480464 | CTD | Fenofibrate results in increased expression of SREBF1 mRNA | PMID:23063693 | Srebf1 | multiple interactions | EXP | | 6480464 | CTD | Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SREBF1 mRNA]; Fenofibrate inhibits the reaction [tyloxapol results in increased expression of SREBF1 protein]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SREBF1 mRNA]]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SREBF1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SREBF1 mRNA] | PMID:19593819 PMID:23063693 PMID:36905866 | Srebf1 | multiple interactions | ISO | Srebf1 (Rattus norvegicus) | 6480464 | CTD | [Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in increased expression of SREBF1 mRNA] | PMID:26973390 | Srebf1 | multiple interactions | ISO | SREBF1 (Homo sapiens) | 6480464 | CTD | Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in increased expression of SREBF1 mRNA]; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in increased expression of SREBF1 protein] | PMID:24735863 | | ||||||||||||||||||||||
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