Sult1c2 (sulfotransferase family, cytosolic, 1C, member 2) - Rat Genome Database

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Gene: Sult1c2 (sulfotransferase family, cytosolic, 1C, member 2) Mus musculus
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Symbol: Sult1c2
Name: sulfotransferase family, cytosolic, 1C, member 2
RGD ID: 1623189
MGI Page MGI
Description: Exhibits sulfotransferase activity. Involved in sulfation. Predicted to localize to cytoplasm. Is expressed in central nervous system; sensory organ; and skeleton. Orthologous to human SULT1C2 (sulfotransferase family 1C member 2); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 2-acetamidofluorene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 1810008N17Rik; ST1C; ST1C1; ST1C2; sulfotransferase 1C2; Sult1c1
RGD Orthologs
Human
Rat
Bonobo
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm19007  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391754,136,665 - 54,152,986 (-)NCBIGRCm39mm39
GRCm39 Ensembl1754,136,665 - 54,153,367 (-)Ensembl
GRCm381753,829,637 - 53,845,958 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1753,829,637 - 53,846,339 (-)EnsemblGRCm38mm10GRCm38
MGSCv371753,968,962 - 53,985,283 (-)NCBIGRCm37mm9NCBIm37
MGSCv361753,294,566 - 53,310,887 (-)NCBImm8
Celera1757,258,480 - 57,274,710 (-)NCBICelera
Cytogenetic Map17CNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-acetamidofluorene  (EXP)
2-Amino-3-methyl-9H-pyrido[2,3-b]indole  (ISO)
2-naphthylamine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-hydroxyphenyl retinamide  (EXP)
4-nitrophenol  (ISO)
5-azacytidine  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (ISO)
butanal  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (EXP)
catechol  (ISO)
cefaloridine  (ISO)
chenodeoxycholic acid  (ISO)
cis-caffeic acid  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
dichloroacetic acid  (EXP)
dorsomorphin  (ISO)
enilconazole  (ISO)
entinostat  (ISO)
ethanol  (ISO)
fenofibrate  (ISO)
fipronil  (EXP,ISO)
flutamide  (ISO)
folic acid  (EXP)
furan  (EXP,ISO)
genistein  (ISO)
glafenine  (ISO)
glutathione  (ISO)
kojic acid  (ISO)
lead diacetate  (EXP)
methotrexate  (ISO)
N,N-diethyl-m-toluamide  (ISO)
N-hydroxy-4-aminobiphenyl  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosomorpholine  (ISO)
nefazodone  (ISO)
nimesulide  (ISO)
ochratoxin A  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
pentanal  (ISO)
perfluorononanoic acid  (ISO)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
pioglitazone  (EXP)
pirinixic acid  (EXP)
pravastatin  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
Propiverine  (ISO)
pyrazinecarboxamide  (ISO)
quercetin  (ISO)
Rebamipide  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium dichromate  (ISO)
streptozocin  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
trans-caffeic acid  (ISO)
tributylstannane  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)
zaragozic acid A  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
sulfation  (IBA,IDA,ISO)

Cellular Component
cytoplasm  (IBA)
lysosome  (IEA)

Molecular Function

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12164856   PMID:12466851   PMID:12477932   PMID:15167709   PMID:15489334   PMID:16141072   PMID:16141073   PMID:19548878  
PMID:21267068   PMID:21677750   PMID:21873635   PMID:24028175   PMID:32325033  


Genomics

Comparative Map Data
Sult1c2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391754,136,665 - 54,152,986 (-)NCBIGRCm39mm39
GRCm39 Ensembl1754,136,665 - 54,153,367 (-)Ensembl
GRCm381753,829,637 - 53,845,958 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1753,829,637 - 53,846,339 (-)EnsemblGRCm38mm10GRCm38
MGSCv371753,968,962 - 53,985,283 (-)NCBIGRCm37mm9NCBIm37
MGSCv361753,294,566 - 53,310,887 (-)NCBImm8
Celera1757,258,480 - 57,274,710 (-)NCBICelera
Cytogenetic Map17CNCBI
SULT1C2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2108,288,639 - 108,309,915 (+)EnsemblGRCh38hg38GRCh38
GRCh382108,288,895 - 108,309,915 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372108,905,351 - 108,926,371 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362108,271,527 - 108,292,803 (+)NCBINCBI36hg18NCBI36
Build 342108,363,612 - 108,384,888NCBI
Celera2103,213,362 - 103,234,637 (+)NCBI
Cytogenetic Map2q12.3NCBI
HuRef2102,504,173 - 102,525,477 (+)NCBIHuRef
CHM1_12108,909,367 - 108,930,641 (+)NCBICHM1_1
Sult1c2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.296,873,697 - 6,904,736 (-)NCBI
Rnor_6.0 Ensembl94,152,589 - 4,168,221 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.094,152,588 - 4,168,355 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.093,191,456 - 3,207,086 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.491,030,264 - 1,168,243 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.191,030,264 - 1,168,243 (-)NCBI
Celera93,009,670 - 3,026,700 (-)NCBICelera
Cytogenetic Map9q11NCBI
SULT1C2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A109,572,466 - 109,592,866 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A109,572,466 - 109,622,211 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A94,468,094 - 94,489,191 (+)NCBIMhudiblu_PPA_v0panPan3
SULT1C2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11035,561,023 - 35,589,999 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1035,563,044 - 35,578,434 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1035,483,649 - 35,512,230 (-)NCBI
ROS_Cfam_1.01036,414,407 - 36,443,621 (-)NCBI
UMICH_Zoey_3.11036,144,418 - 36,173,605 (-)NCBI
UNSW_CanFamBas_1.01036,430,769 - 36,459,752 (-)NCBI
UU_Cfam_GSD_1.01036,619,212 - 36,648,177 (-)NCBI
LOC100623541
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl347,807,832 - 47,824,187 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1347,807,830 - 47,824,199 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2349,978,744 - 49,993,703 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SULT1C2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11411,709,266 - 11,731,318 (+)NCBI
ChlSab1.1 Ensembl1411,711,120 - 11,732,613 (+)Ensembl


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141272Tfv1_mtotal food volume 1 (mouse)Not determined480447765330362Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined17986241186688972Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171206732483054339Mouse
1301454Eae5_msusceptibility to experimental allergic encephalomyelitis 5 (mouse)Not determined172430185958301973Mouse
10412198Sst5_msusceptibility to tuberculosis 5 (mouse)Not determined172485760955405969Mouse
10412204Bbaa29_mB.burgdorferi-associated arthritis 29 (mouse)Not determined172574029459740461Mouse
1302005Loco2_mlocomotor activity 2 (mouse)Not determined172657408160574223Mouse
15039348Nmrs37_mNAFLD-associated magnetic resonance shift 37 (mouse)172750432261504322Mouse
1300703Uvbi2_mUVB induced immunosuppression 2 (mouse)Not determined172831148062311728Mouse
1300589Myaa2_mmodifier of Yaa 2 (mouse)Not determined172982162963821740Mouse
4140955Plgr1_mplague resistance locus 1 (mouse)Not determined3072257564722705Mouse
1300885Mbis4_mMycobacterium bovis-induced systemic lupus erythematosus 4 (mouse)Not determined173495684169858931Mouse
10755514Amzn2_manatomical modifier of Zfp423 2 (mouse)173565926669659396Mouse
12904951Smmq2_msoleus muscle mass QTL 2 (mouse)173648271570482715Mouse
1300592Pcyts5_mplasmacytoma susceptibility 5 (mouse)Not determined173840588672405969Mouse
10755525Lymph2_mlymphocyte differential 2 (mouse)173849862572498625Mouse
10755534Lymph4_mlymphocyte differential 4 (mouse)173849862572498625Mouse
4141319Hmtb8_mhemostasis and thrombosis rebleeding time 8 (mouse)Not determined4022744774227623Mouse
15039324Nmrs48_mNAFLD-associated magnetic resonance shift 48 (mouse)174063218774632187Mouse
26884390Skwq9_mskull length QTL 9, 10 week (mouse)174340000067500000Mouse
26884428Cvht3_mcranial vault height 3, 5 week (mouse)174620000082100000Mouse
35673315Ari1_mantibody response to influenza 1, day 7, IgG2a+IgG2c (mouse)174700000054400000Mouse
14700692Cihvtq1_mcoxsackieviral infection heart viral titre QTL 1 (mouse)174970000069700000Mouse
1357754Ahl3_mage related hearing loss 3 (mouse)Not determined174989696283897108Mouse
4142243Lfnq5_mlung function QTL 5 (mouse)Not determined5143195157227623Mouse
1357532Bmch7_mbone mechanical trait 7 (mouse)Not determined175145143085451617Mouse
4141879Chlq9_mcirculating hormone level QTL 9 (mouse)Not determined175145143085451617Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:78
Count of miRNA genes:72
Interacting mature miRNAs:76
Transcripts:ENSMUST00000023886
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000023886   ⟹   ENSMUSP00000023886
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1753,829,637 - 53,846,339 (-)Ensembl
RefSeq Acc Id: NM_026935   ⟹   NP_081211
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391754,136,665 - 54,152,986 (-)NCBI
GRCm381753,829,637 - 53,845,958 (-)ENTREZGENE
MGSCv371753,968,962 - 53,985,283 (-)RGD
Celera1757,258,480 - 57,274,710 (-)RGD
cM Map17 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_081211   ⟸   NM_026935
- UniProtKB: Q9D939 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000023886   ⟸   ENSMUST00000023886

Promoters
RGD ID:13676422
Promoter ID:EPDNEW_M22360
Type:multiple initiation site
Name:Sult1c2_2
Description:Mus musculus sulfotransferase family, cytosolic, 1C, member 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M22361  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381753,845,816 - 53,845,876EPDNEW
RGD ID:13676424
Promoter ID:EPDNEW_M22361
Type:initiation region
Name:Sult1c2_1
Description:Mus musculus sulfotransferase family, cytosolic, 1C, member 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M22360  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381753,845,942 - 53,846,002EPDNEW
RGD ID:6828735
Promoter ID:MM_KWN:23825
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Liver
Transcripts:OTTMUST00000070552
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361753,985,364 - 53,985,864 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1916333 AgrOrtholog
Ensembl Genes ENSMUSG00000023122 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000023886 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000023886 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro P-loop_NTPase UniProtKB/Swiss-Prot
  Sulfotransferase_dom UniProtKB/Swiss-Prot
KEGG Report mmu:69083 UniProtKB/Swiss-Prot
MGD MGI:1916333 ENTREZGENE
NCBI Gene 69083 ENTREZGENE
Pfam Sulfotransfer_1 UniProtKB/Swiss-Prot
PhenoGen Sult1c2 PhenoGen
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt Q9D939 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q3UNA9 UniProtKB/Swiss-Prot
  Q8R210 UniProtKB/Swiss-Prot