Vcpip1 (valosin containing protein (p97)/p47 complex interacting protein 1) - Rat Genome Database

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Gene: Vcpip1 (valosin containing protein (p97)/p47 complex interacting protein 1) Mus musculus
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Symbol: Vcpip1
Name: valosin containing protein (p97)/p47 complex interacting protein 1
RGD ID: 1552825
MGI Page MGI
Description: Predicted to have thiol-dependent ubiquitin-specific protease activity. Predicted to be involved in several processes, including endoplasmic reticulum membrane fusion; protein modification by small protein conjugation or removal; and protein-DNA covalent cross-linking repair. Localizes to synapse. Orthologous to human VCPIP1 (valosin containing protein interacting protein 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 4932442A08; 5730421J18Rik; 5730538E15Rik; deubiquitinating protein VCIP135; deubiquitinating protein VCPIP1; mKIAA1850; valosin-containing protein p97/p47 complex-interacting protein 1; valosin-containing protein p97/p47 complex-interacting protein p135; Vcip; VCIP135
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3919,788,847 - 9,818,607 (-)NCBIGRCm39mm39
GRCm39 Ensembl19,788,847 - 9,818,607 (-)Ensembl
GRCm3819,718,622 - 9,748,382 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl19,718,622 - 9,748,382 (-)EnsemblGRCm38mm10GRCm38
MGSCv3719,713,273 - 9,738,463 (-)NCBIGRCm37mm9NCBIm37
MGSCv3619,708,406 - 9,733,596 (-)NCBImm8
Celera19,697,685 - 9,724,194 (-)NCBICelera
Cytogenetic Map1A2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
progeria  (IEA)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:14610273   PMID:14988733   PMID:15489334   PMID:16141072   PMID:16141073   PMID:16452087   PMID:21267068   PMID:21811234  
PMID:21873635   PMID:26496610   PMID:28190767   PMID:28378742   PMID:28584101   PMID:29459677   PMID:30457570   PMID:30550785   PMID:32325033   PMID:32649882  


Genomics

Comparative Map Data
Vcpip1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3919,788,847 - 9,818,607 (-)NCBIGRCm39mm39
GRCm39 Ensembl19,788,847 - 9,818,607 (-)Ensembl
GRCm3819,718,622 - 9,748,382 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl19,718,622 - 9,748,382 (-)EnsemblGRCm38mm10GRCm38
MGSCv3719,713,273 - 9,738,463 (-)NCBIGRCm37mm9NCBIm37
MGSCv3619,708,406 - 9,733,596 (-)NCBImm8
Celera19,697,685 - 9,724,194 (-)NCBICelera
Cytogenetic Map1A2NCBI
VCPIP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl866,628,487 - 66,667,231 (-)EnsemblGRCh38hg38GRCh38
GRCh38866,628,487 - 66,667,231 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37867,540,722 - 67,579,466 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36867,705,042 - 67,742,006 (-)NCBINCBI36hg18NCBI36
Celera863,535,483 - 63,572,240 (-)NCBI
Cytogenetic Map8q13.1NCBI
HuRef863,032,538 - 63,071,315 (-)NCBIHuRef
CHM1_1867,597,370 - 67,634,328 (-)NCBICHM1_1
Vcpip1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.259,534,247 - 9,560,889 (+)NCBI
Rnor_6.0 Ensembl59,230,984 - 9,257,934 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.059,231,180 - 9,257,821 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0514,031,258 - 14,057,899 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.459,088,295 - 9,114,936 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.159,088,236 - 9,116,073 (+)NCBI
Celera59,042,984 - 9,069,572 (+)NCBICelera
Cytogenetic Map5q11NCBI
Vcpip1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544412,542,479 - 12,567,971 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544412,542,479 - 12,567,971 (+)NCBIChiLan1.0ChiLan1.0
VCPIP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1864,836,468 - 64,874,818 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl864,842,479 - 64,874,818 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0863,173,116 - 63,210,119 (-)NCBIMhudiblu_PPA_v0panPan3
VCPIP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12916,204,932 - 16,235,893 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2916,209,353 - 16,235,586 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2916,520,420 - 16,552,129 (-)NCBI
ROS_Cfam_1.02916,284,665 - 16,316,409 (-)NCBI
UMICH_Zoey_3.12916,316,618 - 16,348,345 (-)NCBI
UNSW_CanFamBas_1.02916,416,266 - 16,447,999 (-)NCBI
UU_Cfam_GSD_1.02916,672,097 - 16,703,810 (-)NCBI
Vcpip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530367,409,454 - 67,433,444 (-)NCBI
SpeTri2.0NW_0049364967,352,043 - 7,376,023 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VCPIP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl468,073,447 - 68,110,621 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1468,073,403 - 68,109,221 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2474,259,695 - 74,274,272 (+)NCBISscrofa10.2Sscrofa10.2susScr3
VCPIP1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1862,506,541 - 62,546,238 (-)NCBI
ChlSab1.1 Ensembl862,510,808 - 62,546,229 (-)Ensembl
Vero_WHO_p1.0NW_02366603978,961,467 - 79,002,860 (+)NCBI
Vcpip1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474424,664,833 - 24,700,416 (+)NCBI

Position Markers
D1Mit296  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3819,749,730 - 9,749,873UniSTSGRCm38
MGSCv3719,739,811 - 9,739,954UniSTSGRCm37
Celera19,725,549 - 9,725,684UniSTS
Cytogenetic Map1A2UniSTS
cM Map18.3UniSTS
Whitehead Genetic13.3UniSTS
Whitehead/MRC_RH171.54UniSTS
Whitehead_YAC1 UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10412226Alpq4_malcohol preference QTL 4 (mouse)Not determined1122906465Mouse
1301891Alcp25_malcohol preference locus 25 (mouse)Not determined1125132961Mouse
1300834Cia20_mcollagen induced arthritis 20 (mouse)Not determined1125132961Mouse
1301482Morph1_mmorphine antinociception 1 (mouse)Not determined1130297523Mouse
1301275Sle10_msystematic lupus erythematosus susceptibility 10 (mouse)Not determined1281197036812128Mouse
1301370Adip1_madiposity 1 (mouse)Not determined1281197036812128Mouse
13824984Twq5_mtestis weight QTL 5 (mouse)13000000185000000Mouse
1301471Obq2_mobesity QTL 2 (mouse)Not determined1387139637871663Mouse
10043970Obq23_mobesity QTL 23 (mouse)Not determined1494244138942441Mouse
1301011Cplaq4_mcircadian period of locomotor activity 4 (mouse)Not determined1963436143634520Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1995
Count of miRNA genes:711
Interacting mature miRNAs:953
Transcripts:ENSMUST00000057438
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000057438   ⟹   ENSMUSP00000051248
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl19,718,622 - 9,748,382 (-)Ensembl
RefSeq Acc Id: NM_173443   ⟹   NP_775619
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3919,788,847 - 9,818,607 (-)NCBI
GRCm3819,718,622 - 9,748,382 (-)NCBI
MGSCv3719,713,273 - 9,738,463 (-)RGD
Celera19,693,120 - 9,724,194 (-)NCBI
cM Map1 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_775619   ⟸   NM_173443
- UniProtKB: Q8CDG3 (UniProtKB/Swiss-Prot),   A0A0R4J0M9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000051248   ⟸   ENSMUST00000057438
Protein Domains
OTU

Promoters
RGD ID:6817292
Promoter ID:MM_KWN:79
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day3,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Liver,   MEF_B6
Transcripts:UC007AGR.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3619,710,911 - 9,714,967 (-)MPROMDB
RGD ID:6818707
Promoter ID:MM_KWN:80
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Liver,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000052491
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3619,735,846 - 9,738,877 (-)MPROMDB
RGD ID:6873156
Promoter ID:EPDNEW_M29
Type:initiation region
Name:Vcpip1_2
Description:Mus musculus valosin containing protein /p47 complex interactingprotein 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M30  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3819,748,253 - 9,748,313EPDNEW
RGD ID:6873158
Promoter ID:EPDNEW_M30
Type:initiation region
Name:Vcpip1_1
Description:Mus musculus valosin containing protein /p47 complex interactingprotein 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M29  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3819,748,395 - 9,748,455EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1917925 AgrOrtholog
Ensembl Genes ENSMUSG00000045210 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000051248 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000057438 ENTREZGENE, UniProtKB/TrEMBL
InterPro OTU_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VCIP135 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:70675 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1917925 ENTREZGENE
NCBI Gene 70675 ENTREZGENE
PANTHER PTHR14843 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam OTU UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Vcpip1 PhenoGen
PROSITE OTU UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54236 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J0M9 ENTREZGENE, UniProtKB/TrEMBL
  Q05DM9_MOUSE UniProtKB/TrEMBL
  Q3UMT4_MOUSE UniProtKB/TrEMBL
  Q80T83_MOUSE UniProtKB/TrEMBL
  Q8CDG3 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q7TMU9 UniProtKB/Swiss-Prot
  Q8BP90 UniProtKB/Swiss-Prot