Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Cd40 (CD40 antigen) Mus musculus
Analyze
Symbol: Cd40
Name: CD40 antigen
Description: Predicted to have antigen binding activity; protein domain specific binding activity; and ubiquitin protein ligase binding activity. Involved in several processes, including defense response to other organism; positive regulation of B cell activation; and protein kinase B signaling. Localizes to the CD40 receptor complex; external side of plasma membrane; and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; arthritis (multiple); autoimmune hypersensitivity disease (multiple); hematologic cancer (multiple); and hyperimmunoglobulin syndrome (multiple). Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human CD40 (CD40 molecule); PARTICIPATES IN allograft rejection pathway; asthma pathway; autoimmune thyroiditis pathway; INTERACTS WITH (R)-mevalonic acid; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI326936; B-cell surface antigen CD40; Bp50; CD40L receptor; GP39; HIGM1; IGM; IMD3; p50; T-BAM; T-cell differentiation antigen; Tnfrsf5; TRAP; tumor necrosis factor receptor superfamily member 5; tumor necrosis factor receptor superfamily, member 5
Orthologs:
Homo sapiens (human) : CD40 (CD40 molecule)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cd40 (CD40 molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd40 (CD40 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD40 (CD40 molecule)
Canis lupus familiaris (dog) : CD40 (CD40 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd40 (CD40 molecule)
Sus scrofa (pig) : CD40 (CD40 molecule)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm382165,055,614 - 165,071,654 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372164,881,136 - 164,897,154 (+)NCBIGRCm37mm9NCBIm37
MGSCv362164,746,841 - 164,762,859 (+)NCBImm8
Celera2170,992,951 - 171,008,953 (+)NCBICelera
Cytogenetic Map2 H3NCBI
cM Map285.38NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cd40
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1615152
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.