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Gene: Mdh2 (malate dehydrogenase 2, NAD (mitochondrial)) Mus musculus
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Symbol: Mdh2
Name: malate dehydrogenase 2, NAD (mitochondrial)
Description: Exhibits L-malate dehydrogenase activity. Predicted to be involved in several processes, including dicarboxylic acid metabolic process; internal protein amino acid acetylation; and tricarboxylic acid cycle. Localizes to membrane. Is expressed in several structures, including alimentary system; nervous system; respiratory system; sensory organ; and urinary system. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 51. Orthologous to human MDH2 (malate dehydrogenase 2); PARTICIPATES IN citric acid cycle pathway; fructose-1,6-bisphosphatase deficiency pathway; fumaric aciduria pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: malate dehydrogenase, mitochondrial; MDH; Mdh-2; mitochondrial malate dehydrogenase 2, NAD; Mor-1; Mor1
Orthologs:
Homo sapiens (human) : MDH2 (malate dehydrogenase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mdh2 (malate dehydrogenase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mdh2 (malate dehydrogenase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MDH2 (malate dehydrogenase 2)
Canis lupus familiaris (dog) : MDH2 (malate dehydrogenase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mdh2 (malate dehydrogenase 2)
Sus scrofa (pig) : MDH2 (malate dehydrogenase 2)
Chlorocebus sabaeus (African green monkey) : MDH2 (malate dehydrogenase 2)
Heterocephalus glaber (naked mole-rat) : Mdh2 (malate dehydrogenase 2)
more info ...
Related Pseudogenes: Gm11241   Gm12369   Gm12375  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl5135,778,480 - 135,790,398 (+)EnsemblGRCm38mm10GRCm38
GRCm385135,778,649 - 135,790,386 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375136,254,519 - 136,266,256 (+)NCBIGRCm37mm9NCBIm37
MGSCv365136,063,276 - 136,075,013 (+)NCBImm8
Celera5132,786,019 - 132,797,756 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map575.4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Mdh2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10889
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.