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Gene: Ptgs1 (prostaglandin-endoperoxide synthase 1) Mus musculus
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Symbol: Ptgs1
Name: prostaglandin-endoperoxide synthase 1
Description: Predicted to have prostaglandin-endoperoxide synthase activity. Involved in prostaglandin biosynthetic process; regulation of blood pressure; and regulation of cell population proliferation. Localizes to the cytoplasm and photoreceptor outer segment. Used to study pre-eclampsia. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human PTGS1 (prostaglandin-endoperoxide synthase 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Cox-1; Cox-3; COX1; cyclooxygenase 1; cyclooxygenase-1; PGH synthase 1; PGHS-1; Pghs1; PHS 1; prostaglandin G/H synthase 1; prostaglandin H2 synthase 1
Orthologs:
Homo sapiens (human) : PTGS1 (prostaglandin-endoperoxide synthase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ptgs1 (prostaglandin-endoperoxide synthase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptgs1 (prostaglandin-endoperoxide synthase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PTGS1 (prostaglandin-endoperoxide synthase 1)
Canis lupus familiaris (dog) : PTGS1 (prostaglandin-endoperoxide synthase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptgs1 (prostaglandin-endoperoxide synthase 1)
Sus scrofa (pig) : PTGS1 (prostaglandin-endoperoxide synthase 1)
Chlorocebus sabaeus (green monkey) : PTGS1 (prostaglandin-endoperoxide synthase 1)
Heterocephalus glaber (naked mole-rat) : Ptgs1 (prostaglandin-endoperoxide synthase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl236,230,426 - 36,252,272 (+)Ensembl
GRCm38236,216,742 - 36,258,593 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37236,085,946 - 36,107,789 (+)NCBIGRCm37mm9NCBIm37
MGSCv36236,052,536 - 36,074,271 (+)NCBImm8
Celera235,934,252 - 35,956,095 (+)NCBICelera
Cytogenetic Map2 BNCBI
cM Map224.19NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ptgs1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11184
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-01-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.