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Gene: Sesn1 (sestrin 1) Mus musculus
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Symbol: Sesn1
Name: sestrin 1
Description: Predicted to have leucine binding activity and oxidoreductase activity, acting on peroxide as acceptor. Involved in cellular response to amino acid stimulus; negative regulation of cell growth; and regulation of intracellular signal transduction. Predicted to colocalize with the GATOR2 complex; TORC2 complex; and cytoplasm. Is expressed in cortical plate. Orthologous to human SESN1 (sestrin 1); PARTICIPATES IN p53 signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110002G11Rik; AU044290; MGC118148; p53 regulated Pa26 nuclear protein; p53-regulated protein PA26; Pa26; Sest1; sestrin-1
Orthologs:
Homo sapiens (human) : SESN1 (sestrin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sesn1 (sestrin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sesn1 (sestrin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SESN1 (sestrin 1)
Canis lupus familiaris (dog) : SESN1 (sestrin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sesn1 (sestrin 1)
Sus scrofa (pig) : SESN1 (sestrin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381041,810,574 - 41,908,436 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371041,530,380 - 41,628,242 (+)NCBIGRCm37mm9NCBIm37
MGSCv361041,575,864 - 41,596,839 (+)NCBImm8
Celera1042,690,911 - 42,787,751 (+)NCBICelera
Cytogenetic Map10 B2NCBI
cM Map1022.77NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Sesn1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1316758
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.