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Gene: Arfgef2 (ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)) Mus musculus
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Symbol: Arfgef2
Name: ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
Description: Predicted to have several functions, including ARF guanyl-nucleotide exchange factor activity; GABA receptor binding activity; and protein kinase A regulatory subunit binding activity. Predicted to be involved in several processes, including Golgi to plasma membrane transport; positive regulation of tumor necrosis factor production; and receptor recycling. Predicted to localize to several cellular components, including the Golgi apparatus; microtubule cytoskeleton; and recycling endosome. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Is expressed in brown fat; central nervous system; duodenum; thymus; and trunk. Orthologous to human ARFGEF2 (ADP ribosylation factor guanine nucleotide exchange factor 2); INTERACTS WITH aflatoxin B1; bisphenol A; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI463430; AW493672; BIG2; brefeldin A-inhibited GEP 2; brefeldin A-inhibited guanine nucleotide-exchange protein 2; E230011G24Rik
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm382166,805,451 - 166,898,052 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372166,631,081 - 166,723,552 (+)NCBIGRCm37mm9NCBIm37
MGSCv362166,496,769 - 166,589,258 (+)NCBImm8
Celera2172,745,033 - 172,837,457 (+)NCBICelera
Cytogenetic Map2 H3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Arfgef2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1332439
Created: 2005-02-01
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.