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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:fenofibrate
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Accession:CHEBI:5001 term browser browse the term
Definition:A chlorobenzophenone that is (4-chlorophenyl)(phenyl)methanone substituted by a [2-methyl-1-oxo-1-(propan-2-yloxy)propan-2-yl]oxy group at position 1 on the phenyl ring.
Synonyms:exact_synonym: propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate
 related_synonym: 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester;   FNF;   Finofibrate;   Formula=C20H21ClO4;   InChI=1S/C20H21ClO4/c1-13(2)24-19(23)20(3,4)25-17-11-7-15(8-12-17)18(22)14-5-9-16(21)10-6-14/h5-13H,1-4H3;   InChIKey=YMTINGFKWWXKFG-UHFFFAOYSA-N;   Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate;   Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate;   Lipantil (TN);   Procetofen;   SMILES=CC(C)OC(=O)C(C)(C)Oc1ccc(cc1)C(=O)c1ccc(Cl)cc1;   Tricor (TN)
 xref: CAS:49562-28-9;   DrugBank:DB01039;   Drug_Central:1152;   HMDB:HMDB0015173;   KEGG:C07586;   KEGG:D00565;   LINCS:LSM-3107
 xref_mesh: MESH:D011345
 xref: PMID:17449930;   PMID:18212815;   Patent:DE2250327;   Patent:US4058552;   Reaxys:2062462;   Wikipedia:Fenofibrate


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fenofibrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A1bg alpha-1-B glycoprotein decreases expression EXP Fenofibrate results in decreased expression of A1BG protein CTD PMID:20118634 NCBI chr 7:102,294,805...102,298,522
Ensembl chr 7:102,294,797...102,298,522
JBrowse link
G Aadac arylacetamide deacetylase increases expression ISO Fenofibrate results in increased expression of AADAC mRNA CTD PMID:25572481 NCBI chr 2:150,146,234...150,157,480
Ensembl chr 2:150,146,234...150,157,480
JBrowse link
G Aars1 alanyl-tRNA synthetase 1 increases expression EXP Fenofibrate results in increased expression of AARS mRNA CTD PMID:25596134 NCBI chr19:43,193,264...43,215,281
Ensembl chr19:43,193,257...43,215,281
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 increases expression ISO Fenofibrate results in increased expression of ABCA1 mRNA; Fenofibrate results in increased expression of ABCA1 protein CTD PMID:19201410 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases expression
decreases activity
ISO
EXP
Fenofibrate inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Fenofibrate results in decreased expression of ABCB11 mRNA
Fenofibrate results in decreased activity of ABCB11 protein
CTD PMID:20829430, PMID:23956101, PMID:24014644, PMID:27765674 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO Fenofibrate inhibits the reaction [ABCB1 protein results in increased transport of Vincristine] CTD PMID:16316932 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression ISO Fenofibrate results in increased expression of ABCB4 mRNA CTD PMID:17118139, PMID:19118567 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb6 ATP binding cassette subfamily B member 6 decreases expression EXP Fenofibrate results in decreased expression of ABCB6 mRNA CTD PMID:25596134 NCBI chr 9:82,373,950...82,382,228
Ensembl chr 9:82,373,946...82,382,272
JBrowse link
G Abcb9 ATP binding cassette subfamily B member 9 increases expression EXP Fenofibrate results in increased expression of ABCB9 mRNA CTD PMID:25596134 NCBI chr12:37,923,974...37,956,678
Ensembl chr12:37,923,528...37,958,363
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression EXP Fenofibrate results in increased expression of ABCC2 mRNA CTD PMID:27765674 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 decreases expression EXP Fenofibrate results in decreased expression of ABCC3 mRNA CTD PMID:25596134 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression EXP Fenofibrate results in increased expression of ABCC4 mRNA CTD PMID:27765674 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Abcd3 ATP binding cassette subfamily D member 3 increases expression ISO Fenofibrate results in increased expression of ABCD3 mRNA CTD PMID:17118139 NCBI chr 2:225,335,708...225,389,120
Ensembl chr 2:225,335,718...225,389,120
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 increases expression EXP Fenofibrate results in increased expression of ABCG1 mRNA CTD PMID:25596134 NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 increases expression EXP Fenofibrate results in increased expression of ABCG5 mRNA CTD PMID:27765674 NCBI chr 6:7,935,771...7,961,207
Ensembl chr 6:7,935,771...7,961,207
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 increases expression EXP Fenofibrate results in increased expression of ABCG8 mRNA CTD PMID:27765674 NCBI chr 6:7,961,413...7,980,708
Ensembl chr 6:7,961,413...7,980,708
JBrowse link
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B increases expression EXP Fenofibrate results in increased expression of ABHD4 mRNA CTD PMID:25596134 NCBI chr15:32,888,233...32,906,861
Ensembl chr15:32,894,938...32,906,850
JBrowse link
G Abi3bp ABI family member 3 binding protein decreases expression ISO Fenofibrate results in decreased expression of ABI3BP mRNA CTD PMID:25572481 NCBI chr11:46,206,932...46,422,791
Ensembl chr11:46,208,075...46,369,577
JBrowse link
G Acaa1a acetyl-CoA acyltransferase 1A increases expression
multiple interactions
affects expression
ISO
EXP
Fenofibrate results in increased expression of ACAA1A mRNA
Fenofibrate results in increased expression of ACAA1 mRNA
Fenofibrate promotes the reaction [Pyrazinamide results in increased expression of ACAA1 mRNA]; Pyrazinamide promotes the reaction [Fenofibrate results in increased expression of ACAA1 mRNA]
Fenofibrate affects the expression of ACAA1A mRNA
CTD PMID:11798191, PMID:20801182, PMID:24752549, PMID:27071702 NCBI chr 8:128,027,880...128,036,471
Ensembl chr 8:128,027,958...128,036,236
JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 affects expression
increases expression
EXP
ISO
Fenofibrate affects the expression of ACAA2 mRNA
Fenofibrate results in increased expression of ACAA2 mRNA
Fenofibrate results in increased expression of ACAA2 mRNA; Fenofibrate results in increased expression of ACAA2 protein
CTD PMID:20118634, PMID:20801182, PMID:25572481, PMID:27665778 NCBI chr18:70,733,872...70,762,395
Ensembl chr18:70,733,872...70,762,395
JBrowse link
G Acaca acetyl-CoA carboxylase alpha multiple interactions
decreases expression
increases expression
ISO NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA]
Fenofibrate results in decreased expression of ACACA protein
CTD PMID:23063693, PMID:24752549 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Acacb acetyl-CoA carboxylase beta multiple interactions
increases expression
ISO NR1H2 gene mutant form affects the reaction [Fenofibrate results in increased expression of ACACB mRNA]; NR1H3 gene mutant form affects the reaction [Fenofibrate results in increased expression of ACACB mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACB mRNA] CTD PMID:17118139, PMID:23063693 NCBI chr12:48,127,149...48,238,969
Ensembl chr12:48,127,149...48,238,887
JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain increases expression ISO Fenofibrate results in increased expression of ACADL mRNA CTD PMID:17690133 NCBI chr 9:73,833,368...73,871,857
Ensembl chr 9:73,833,388...73,871,888
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain increases expression ISO Fenofibrate results in increased expression of ACADM mRNA CTD PMID:11798191, PMID:17690133, PMID:19124612, PMID:24752549, PMID:25572481 NCBI chr 2:260,124,418...260,148,589
Ensembl chr 2:260,124,418...260,148,589
JBrowse link
G Acads acyl-CoA dehydrogenase short chain multiple interactions EXP Fenofibrate inhibits the reaction [ACADS protein affects the cleavage of CASP3 protein]; Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of ACADS mRNA]; Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of and results in decreased activity of ACADS protein] CTD PMID:26989860 NCBI chr12:47,254,503...47,263,747
Ensembl chr12:47,254,484...47,263,747
JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain increases expression ISO
EXP
Fenofibrate results in increased expression of ACADVL mRNA CTD PMID:17118139, PMID:24752549, PMID:27665778 NCBI chr10:56,619,321...56,624,468
Ensembl chr10:56,619,303...56,624,526
JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 multiple interactions
increases expression
EXP
ISO
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of ACAT1 mRNA
Fenofibrate results in increased expression of ACAT1 mRNA
CTD PMID:18253720, PMID:24752549 NCBI chr 8:58,166,990...58,195,884
Ensembl chr 8:58,166,990...58,195,884
JBrowse link
G Acly ATP citrate lyase increases expression
multiple interactions
ISO Fenofibrate results in increased expression of ACLY mRNA
PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACLY mRNA]
CTD PMID:23063693 NCBI chr10:88,392,248...88,442,845
Ensembl chr10:88,392,248...88,442,845
JBrowse link
G Aco1 aconitase 1 increases expression EXP Fenofibrate results in increased expression of ACO1 mRNA CTD PMID:17264098 NCBI chr 5:56,425,076...56,481,218
Ensembl chr 5:56,425,024...56,481,218
JBrowse link
G Aco2 aconitase 2 increases expression ISO Fenofibrate results in increased expression of ACO2 mRNA CTD PMID:24752549 NCBI chr 7:123,102,493...123,145,608
Ensembl chr 7:123,102,468...123,145,635
JBrowse link
G Acot1 acyl-CoA thioesterase 1 increases expression ISO
EXP
Fenofibrate results in increased expression of ACOT1 mRNA CTD PMID:11798191, PMID:17690133, PMID:27665778 NCBI chr 6:107,485,088...107,493,082
Ensembl chr 6:107,485,249...107,493,798
JBrowse link
G Acot2 acyl-CoA thioesterase 2 affects expression
multiple interactions
increases expression
EXP Fenofibrate affects the expression of ACOT2 mRNA
Fenofibrate results in increased expression of and results in increased activity of ACOT2 protein
Fenofibrate results in increased expression of ACOT2 mRNA
CTD PMID:16595124, PMID:20801182, PMID:27665778 NCBI chr 6:107,460,596...107,468,324
Ensembl chr 6:107,460,668...107,467,487
JBrowse link
G Acot4 acyl-CoA thioesterase 4 increases expression EXP Fenofibrate results in increased expression of ACOT4 mRNA CTD PMID:27665778 NCBI chr 6:107,517,668...107,522,952
Ensembl chr 6:107,517,668...107,522,952
JBrowse link
G Acox1 acyl-CoA oxidase 1 affects expression
multiple interactions
increases expression
EXP
ISO
Fenofibrate affects the expression of ACOX1 mRNA
[Fenofibrate co-treated with Fatty Acids, Nonesterified] results in increased expression of ACOX1 protein; [Fenofibrate co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of ACOX1 mRNA]; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of ACOX1 protein]; Fenofibrate promotes the reaction [Fatty Acids, Nonesterified results in increased expression of ACOX1 mRNA]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of ACOX1 protein]
Fenofibrate results in increased expression of ACOX1 mRNA; Fenofibrate results in increased expression of ACOX1 protein
Fenofibrate inhibits the reaction [Zoledronic Acid results in decreased expression of ACOX1 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 protein]
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of ACOX1 mRNA
CTD PMID:16707586, PMID:17118139, PMID:17690133, PMID:18253720, PMID:18775883, PMID:19395589, PMID:20801182, PMID:22301950, PMID:23063693, PMID:24534255, PMID:24735863, PMID:24752549, PMID:24986865, PMID:25572481, PMID:28871336 NCBI chr10:104,724,534...104,748,003
Ensembl chr10:104,722,958...104,748,050
JBrowse link
G Acox2 acyl-CoA oxidase 2 multiple interactions ISO Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of ACOX2 mRNA] CTD PMID:28871336 NCBI chr15:18,449,304...18,481,472
Ensembl chr15:18,451,144...18,481,470
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 increases expression
multiple interactions
decreases expression
affects expression
ISO
EXP
Fenofibrate results in increased expression of ACSL1 mRNA; Fenofibrate results in increased expression of ACSL1 protein
PPARA protein promotes the reaction [Fenofibrate results in increased expression of ACSL1 protein]
PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACSL1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACSL1 protein]
Fenofibrate results in decreased expression of ACSL1 protein
Fenofibrate affects the expression of ACSL1 mRNA
CTD PMID:10600944, PMID:17118139, PMID:20118634, PMID:20801182, PMID:24752549, PMID:25596134 NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 increases expression ISO Fenofibrate results in increased expression of ACSL4 mRNA CTD PMID:17118139 NCBI chr  X:113,596,247...113,660,024
Ensembl chr  X:113,596,239...113,659,944
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 increases expression ISO Fenofibrate results in increased expression of ACSL5 mRNA CTD PMID:17118139 NCBI chr 1:276,240,703...276,290,012
Ensembl chr 1:276,240,703...276,290,008
JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 increases expression EXP Fenofibrate results in increased expression of ACSL6 mRNA CTD PMID:16595124 NCBI chr10:39,654,771...39,717,592
Ensembl chr10:39,655,455...39,719,312
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 decreases expression ISO Fenofibrate results in decreased expression of ACSS2 mRNA CTD PMID:25572481 NCBI chr 3:151,032,925...151,075,856
Ensembl chr 3:151,032,952...151,075,856
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of ACTA2 protein] CTD PMID:28871336 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Adcy1 adenylate cyclase 1 decreases expression ISO Fenofibrate results in decreased expression of ADCY1 mRNA CTD PMID:25596134 NCBI chr14:87,311,970...87,429,880
Ensembl chr14:87,312,203...87,421,659
JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) decreases expression ISO Fenofibrate results in decreased expression of ADH1C mRNA CTD PMID:25572481 NCBI chr 2:243,550,655...243,562,243
Ensembl chr 2:243,550,627...243,687,857
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide decreases expression ISO Fenofibrate results in decreased expression of ADH4 mRNA CTD PMID:25572481 NCBI chr 2:243,702,035...243,720,063
Ensembl chr 2:243,700,784...243,740,899
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression
multiple interactions
ISO Fenofibrate results in increased expression of ADIPOQ protein
[candesartan co-treated with Fenofibrate] results in increased expression of ADIPOQ protein; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of ADIPOQ protein]
CTD PMID:16443859, PMID:24735863 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adipor2 adiponectin receptor 2 increases expression ISO Fenofibrate results in increased expression of ADIPOR2 mRNA CTD PMID:16306350 NCBI chr 4:151,412,135...151,480,108
Ensembl chr 4:151,414,684...151,428,894
JBrowse link
G Agrn agrin decreases expression EXP Fenofibrate results in decreased expression of AGRN mRNA CTD PMID:25596134 NCBI chr 5:173,589,910...173,622,813
Ensembl chr 5:173,589,819...173,622,645
JBrowse link
G Agt angiotensinogen multiple interactions ISO Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of EDN1 mRNA]; Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of JUN mRNA]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL1A1 mRNA]]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL3A1 mRNA]]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of VEGFA protein]] CTD PMID:31016362 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 decreases expression ISO Fenofibrate results in decreased expression of AGXT2 mRNA CTD PMID:25572481 NCBI chr 2:60,337,667...60,379,144
Ensembl chr 2:60,337,667...60,379,420
JBrowse link
G Ahr aryl hydrocarbon receptor affects activity
multiple interactions
ISO
EXP
Fenofibrate affects the activity of AHR protein
Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of EDN1 mRNA]; Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of JUN mRNA]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL1A1 mRNA]]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL3A1 mRNA]]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of VEGFA protein]]
CTD PMID:25596134, PMID:31016362 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Aifm2 apoptosis inducing factor, mitochondria associated 2 increases expression EXP
ISO
Fenofibrate results in increased expression of AIFM2 mRNA CTD PMID:25596134 NCBI chr20:31,329,047...31,353,548
Ensembl chr20:31,339,787...31,352,906
JBrowse link
G Ak4 adenylate kinase 4 affects expression EXP Fenofibrate affects the expression of AK4 mRNA CTD PMID:25596134 NCBI chr 5:120,250,318...120,309,153
Ensembl chr 5:120,250,616...120,305,897
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 multiple interactions
decreases activity
ISO Fenofibrate inhibits the reaction [AKR1B10 protein results in increased reduction of Daunorubicin]; Fenofibrate inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]
Fenofibrate results in decreased activity of AKR1B10 protein; Fenofibrate results in decreased activity of AKR1B10 protein mutant form
CTD PMID:18325492, PMID:19028477 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO Fenofibrate results in increased expression of AKR1C2 mRNA CTD PMID:25596134 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Alb albumin multiple interactions ISO dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of ICAM1 mRNA]]; dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of SELE mRNA]]; dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of VCAM1 mRNA]]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased degradation of NFKBIA protein]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of ICAM1 mRNA]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of NFKB1 protein]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of RELA protein]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of SELE mRNA]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of VCAM1 mRNA]; PRKAA1 protein affects the reaction [Fenofibrate results in decreased susceptibility to ALB protein modified form] CTD PMID:20580385 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 increases expression ISO Fenofibrate results in increased expression of ALDH1A2 mRNA CTD PMID:17118139 NCBI chr 8:77,640,234...77,719,488
Ensembl chr 8:77,640,222...77,719,489
JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 increases expression ISO Fenofibrate results in increased expression of ALDH6A1 mRNA CTD PMID:24752549 NCBI chr 6:108,146,552...108,167,185
Ensembl chr 6:108,146,582...108,167,185
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression EXP Fenofibrate results in increased expression of ALDOA mRNA CTD PMID:25596134 NCBI chr 1:198,228,387...198,233,988
Ensembl chr 1:198,228,387...198,233,588
JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type increases expression ISO Fenofibrate results in increased expression of ALOX12 mRNA CTD PMID:12759900 NCBI chr10:56,851,734...56,864,049
Ensembl chr10:56,851,734...56,864,005
JBrowse link
G Alpk2 alpha-kinase 2 increases expression ISO Fenofibrate results in increased expression of ALPK2 mRNA CTD PMID:25572481 NCBI chr18:60,960,009...61,072,116
Ensembl chr18:60,960,662...61,057,365
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated decreases expression ISO Fenofibrate results in decreased expression of ALPL mRNA CTD PMID:25572481 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Anapc11 anaphase promoting complex subunit 11 multiple interactions
decreases expression
ISO PPARA protein affects the reaction [Fenofibrate results in decreased expression of ANAPC11 mRNA] CTD PMID:21318169 NCBI chr10:109,774,779...109,785,877
Ensembl chr10:109,774,878...109,785,877
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO
EXP
Fenofibrate results in increased expression of ANGPTL4 mRNA CTD PMID:17118139, PMID:25572481, PMID:25596134, PMID:27665778 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
JBrowse link
G Ankra2 ankyrin repeat family A member 2 increases expression ISO Fenofibrate results in increased expression of ANKRA2 mRNA CTD PMID:25596134 NCBI chr  X:82,407,601...82,418,229
Ensembl chr  X:82,407,598...82,418,425
JBrowse link
G Anxa3 annexin A3 decreases expression EXP Fenofibrate results in decreased expression of ANXA3 protein CTD PMID:20118634 NCBI chr14:14,371,921...14,426,503
Ensembl chr14:14,364,008...14,426,437
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 multiple interactions
increases expression
EXP [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of APEX1 mRNA
Fenofibrate results in increased expression of APEX1 mRNA
CTD PMID:17264098, PMID:18253720, PMID:18775883 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Apoa1 apolipoprotein A1 decreases expression
multiple interactions
ISO
EXP
Fenofibrate results in decreased expression of APOA1 mRNA; Fenofibrate results in decreased expression of APOA1 protein
[Fenofibrate co-treated with Pyrazinamide] results in increased expression of APOA1 mRNA
Fenofibrate promotes the reaction [APOA1 protein results in increased secretion of Lipids]; PPARA protein affects the reaction [Fenofibrate promotes the reaction [APOA1 protein results in increased secretion of Lipids]]
Fenofibrate promotes the reaction [APOA1 protein results in increased secretion of Lipids]; PPARA protein inhibits the reaction [Fenofibrate results in decreased expression of APOA1 mRNA]
CTD PMID:7983038, PMID:19201410, PMID:19445040, PMID:27071702 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apoa4 apolipoprotein A4 decreases expression ISO Fenofibrate results in decreased expression of APOA4 mRNA CTD PMID:11798191 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
G Apob apolipoprotein B decreases expression ISO Fenofibrate results in decreased expression of APOB protein CTD PMID:21411093 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Apoc3 apolipoprotein C3 affects expression
decreases expression
EXP
ISO
Fenofibrate affects the expression of APOC3 mRNA
Fenofibrate results in decreased expression of APOC3 mRNA; Fenofibrate results in decreased expression of APOC3 protein
CTD PMID:8847480, PMID:10799317, PMID:20801182, PMID:24752549 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO Fenofibrate affects the reaction [PSEN1 protein affects the cleavage of APP protein] CTD PMID:17962197 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Aqp9 aquaporin 9 decreases expression ISO Fenofibrate results in decreased expression of AQP9 mRNA CTD PMID:25572481 NCBI chr 8:77,559,621...77,599,781
Ensembl chr 8:77,559,624...77,599,781
JBrowse link
G Arfgef2 ADP ribosylation factor guanine nucleotide exchange factor 2 increases expression
decreases expression
ISO
EXP
Fenofibrate results in increased expression of ARFGEF2 mRNA
Fenofibrate results in decreased expression of ARFGEF2 mRNA
CTD PMID:25596134 NCBI chr 3:163,570,435...163,656,612
Ensembl chr 3:163,570,532...163,656,626
JBrowse link
G Arhgef10 Rho guanine nucleotide exchange factor 10 decreases expression EXP Fenofibrate results in decreased expression of ARHGEF10 mRNA CTD PMID:25596134 NCBI chr16:79,725,629...79,817,065
Ensembl chr16:79,725,643...79,793,619
JBrowse link
G Arih1 ariadne RBR E3 ubiquitin protein ligase 1 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of ARIH1 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of ARIH1 mRNA]
CTD PMID:21318169 NCBI chr 8:64,166,359...64,268,555
Ensembl chr 8:64,166,360...64,268,555
JBrowse link
G Arl1 ADP-ribosylation factor like GTPase 1 decreases expression EXP Fenofibrate results in decreased expression of ARL1 mRNA CTD PMID:25596134 NCBI chr 7:29,282,411...29,293,455
Ensembl chr 7:29,282,305...29,293,399
JBrowse link
G Asb6 ankyrin repeat and SOCS box-containing 6 multiple interactions
increases expression
ISO [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of ASB6 mRNA
Fenofibrate results in increased expression of ASB6 mRNA
CTD PMID:21318169 NCBI chr 3:9,659,707...9,664,445
Ensembl chr 3:9,659,710...9,664,318
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression EXP
ISO
Fenofibrate results in increased expression of ASNS mRNA CTD PMID:25596134 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Ate1 arginyltransferase 1 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of ATE1 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of ATE1 mRNA]
CTD PMID:21318169 NCBI chr 1:200,810,741...200,885,593
NCBI chr 1:200,958,564...201,082,100
Ensembl chr 1:200,810,771...201,082,727
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions
increases expression
ISO
EXP
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of ATF3 mRNA
Fenofibrate results in increased expression of ATF3 mRNA
CTD PMID:18978307, PMID:25596134 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atf4 activating transcription factor 4 affects activity ISO
EXP
Fenofibrate affects the activity of ATF4 protein CTD PMID:25596134 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atg12 autophagy related 12 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of ATG12 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of ATG12 mRNA]
CTD PMID:21318169 NCBI chr18:40,721,799...40,732,143
Ensembl chr18:40,721,800...40,732,126
JBrowse link
G Atg7 autophagy related 7 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of ATG7 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of ATG7 mRNA]
CTD PMID:21318169 NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 decreases expression EXP Fenofibrate results in decreased expression of ATP2A2 protein CTD PMID:20118634 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326
JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 increases expression ISO Fenofibrate results in increased expression of ATP2B4 mRNA CTD PMID:25572481 NCBI chr13:50,091,644...50,153,808
Ensembl chr13:50,091,430...50,153,823
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in increased expression of BAX protein] CTD PMID:26989860 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcat1 branched chain amino acid transaminase 1 decreases expression ISO Fenofibrate results in decreased expression of BCAT1 mRNA CTD PMID:25596134 NCBI chr 4:179,259,305...179,340,021
Ensembl chr 4:179,259,308...179,339,795
JBrowse link
G Bcat2 branched chain amino acid transaminase 2 increases expression ISO Fenofibrate results in increased expression of BCAT2 mRNA CTD PMID:25596134 NCBI chr 1:101,553,900...101,572,103
Ensembl chr 1:101,554,642...101,572,080
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase decreases activity EXP Fenofibrate results in decreased activity of BCKDK protein CTD PMID:19819289 NCBI chr 1:199,351,628...199,356,299
Ensembl chr 1:199,351,628...199,356,881
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO
EXP
Fenofibrate results in decreased expression of BCL2 mRNA
Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of BCL2 protein]
CTD PMID:15843896, PMID:26989860 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2a1 BCL2-related protein A1 decreases expression ISO Fenofibrate results in decreased expression of BCL2A1 mRNA CTD PMID:20520642 NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO Fenofibrate results in decreased expression of BCL2L1 mRNA CTD PMID:20520642 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl3 BCL3, transcription coactivator decreases expression ISO Fenofibrate results in decreased expression of BCL3 mRNA CTD PMID:25596134 NCBI chr 1:80,730,758...80,745,273
Ensembl chr 1:80,730,499...80,744,831
JBrowse link
G Bcr BCR activator of RhoGEF and GTPase multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of BCR mRNA CTD PMID:18253720 NCBI chr20:14,421,250...14,546,406
Ensembl chr20:14,421,141...14,545,772
JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 decreases expression EXP Fenofibrate results in decreased expression of BDH1 protein CTD PMID:20118634 NCBI chr11:72,577,547...72,619,435
Ensembl chr11:72,578,533...72,614,176
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 decreases expression ISO
EXP
Fenofibrate results in decreased expression of BHLHE40 mRNA CTD PMID:25596134 NCBI chr 4:140,703,619...140,709,319
Ensembl chr 4:140,703,619...140,709,319
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO Fenofibrate results in decreased expression of BIRC3 mRNA CTD PMID:20520642 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Bmf Bcl2 modifying factor increases expression
decreases expression
ISO
EXP
Fenofibrate results in increased expression of BMF mRNA
Fenofibrate results in decreased expression of BMF mRNA
CTD PMID:25572481, PMID:25596134 NCBI chr 3:110,303,515...110,324,125
Ensembl chr 3:110,306,067...110,324,084
JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression EXP Fenofibrate results in increased expression of BNIP3 mRNA CTD PMID:25596134 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Brap BRCA1 associated protein affects expression
multiple interactions
ISO Fenofibrate affects the expression of BRAP mRNA
PPARA protein affects the reaction [Fenofibrate affects the expression of BRAP mRNA]
CTD PMID:21318169 NCBI chr12:40,381,892...40,417,764
Ensembl chr12:40,383,577...40,417,654
JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex, subunit 3 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of BRCC3 mRNA
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of BRCC3 mRNA
CTD PMID:21318169 NCBI chr 9:9,863,380...9,865,920
Ensembl chr 9:9,863,404...9,865,920
JBrowse link
G Brd2 bromodomain containing 2 decreases expression EXP Fenofibrate results in decreased expression of BRD2 mRNA CTD PMID:25596134 NCBI chr20:3,910,555...3,921,074
Ensembl chr20:3,910,555...3,917,426
Ensembl chr20:3,910,555...3,917,426
JBrowse link
G Btg2 BTG anti-proliferation factor 2 affects expression EXP Fenofibrate affects the expression of BTG2 mRNA CTD PMID:25596134 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G C9 complement C9 decreases expression ISO Fenofibrate results in decreased expression of C9 mRNA CTD PMID:11798191 NCBI chr 2:55,775,562...55,823,807
Ensembl chr 2:55,775,274...55,823,826
JBrowse link
G Calm1 calmodulin 1 affects expression EXP Fenofibrate affects the expression of CALM1 mRNA CTD PMID:20801182 NCBI chr 6:124,217,241...124,225,292
Ensembl chr 6:124,217,241...124,225,292
JBrowse link
G Canx calnexin increases expression
multiple interactions
ISO Fenofibrate results in increased expression of CANX mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of CANX mRNA]
CTD PMID:21318169 NCBI chr10:35,800,942...35,833,939
Ensembl chr10:35,800,942...35,833,861
JBrowse link
G Casp3 caspase 3 increases cleavage
decreases expression
multiple interactions
ISO
EXP
Fenofibrate results in increased cleavage of CASP3 protein
Fenofibrate results in decreased expression of CASP3 protein
[ESR1 protein results in increased susceptibility to Estradiol] inhibits the reaction [Fenofibrate results in decreased expression of CASP3 protein]
Fenofibrate inhibits the reaction [ACADS protein affects the cleavage of CASP3 protein]; Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of CASP3 protein]
CTD PMID:20520642, PMID:26989860, PMID:29134746 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp4 caspase 4 increases expression EXP Fenofibrate results in increased expression of CASP4 mRNA CTD PMID:17264098 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
JBrowse link
G Cat catalase multiple interactions
increases expression
increases activity
EXP [Fenofibrate co-treated with Diethylnitrosamine] results in increased activity of CAT protein; [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CAT mRNA
Fenofibrate results in increased expression of CAT mRNA
Fenofibrate results in increased activity of CAT protein
CTD PMID:17264098, PMID:18253720 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav1 caveolin 1 increases expression ISO Fenofibrate results in increased expression of CAV1 mRNA CTD PMID:15314095 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Cblb Cbl proto-oncogene B increases expression
multiple interactions
ISO Fenofibrate results in increased expression of CBLB mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of CBLB mRNA]
CTD PMID:21318169 NCBI chr11:51,037,383...51,202,761
Ensembl chr11:51,037,393...51,202,820
JBrowse link
G Ccdc90b coiled-coil domain containing 90B increases expression EXP Fenofibrate results in increased expression of CCDC90B mRNA CTD PMID:25596134 NCBI chr 1:157,403,595...157,417,153
Ensembl chr 1:157,403,595...157,417,147
JBrowse link
G Ccl12 chemokine (C-C motif) ligand 12 increases expression ISO Fenofibrate results in increased expression of CCL13 mRNA CTD PMID:25572481 NCBI chr10:69,476,866...69,478,416
Ensembl chr10:69,476,775...69,478,462
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
decreases expression
ISO Fenofibrate inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; Fenofibrate inhibits the reaction [Glucose results in increased expression of CCL2 protein]; Fenofibrate inhibits the reaction [Glucose results in increased secretion of CCL2 protein]
Fenofibrate results in decreased expression of CCL2 mRNA; Fenofibrate results in decreased expression of CCL2 protein
Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein]
CTD PMID:15968640, PMID:16306350, PMID:16600694, PMID:18356826, PMID:19132243 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO Fenofibrate inhibits the reaction [Chenodeoxycholic Acid results in increased expression of CCL5 mRNA]; Fenofibrate inhibits the reaction [Chenodeoxycholic Acid results in increased expression of CCL5 protein]; Fenofibrate inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; Fenofibrate inhibits the reaction [TNF protein results in increased expression of CCL5 protein] CTD PMID:12126966, PMID:12586603 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccn1 cellular communication network factor 1 decreases expression ISO Fenofibrate results in decreased expression of CCN1 mRNA CTD PMID:25572481 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Ccnd1 cyclin D1 decreases expression
increases expression
multiple interactions
ISO
EXP
Fenofibrate results in decreased expression of CCND1 mRNA; Fenofibrate results in decreased expression of CCND1 protein
Fenofibrate results in increased expression of CCND1 protein
ESR1 protein inhibits the reaction [Fenofibrate results in increased expression of CCND1 protein]; Estradiol inhibits the reaction [Fenofibrate results in increased expression of CCND1 protein]
Fenofibrate results in increased expression of CCND1 mRNA
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CCND1 mRNA
CTD PMID:16569247, PMID:17264098, PMID:18253720, PMID:18978307, PMID:20520642, PMID:29134746 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccng2 cyclin G2 decreases expression
increases expression
ISO
EXP
Fenofibrate results in decreased expression of CCNG2 mRNA
Fenofibrate results in increased expression of CCNG2 mRNA
CTD PMID:25596134 NCBI chr14:16,267,572...16,276,068
Ensembl chr14:16,267,573...16,276,068
JBrowse link
G Ccnt1 cyclin T1 multiple interactions EXP Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein] CTD PMID:20828602 NCBI chr 7:140,215,052...140,245,958
Ensembl chr 7:140,219,551...140,245,723
JBrowse link
G Cd14 CD14 molecule increases expression ISO Fenofibrate results in increased expression of CD14 mRNA CTD PMID:25572481 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd36 CD36 molecule increases expression EXP
ISO
Fenofibrate results in increased expression of CD36 mRNA CTD PMID:16707586, PMID:17118139, PMID:25572481 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd40 CD40 molecule decreases expression ISO Fenofibrate results in decreased expression of CD40 mRNA CTD PMID:20520642 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cd40lg CD40 ligand multiple interactions
decreases expression
ISO candesartan promotes the reaction [Fenofibrate results in decreased expression of CD40LG protein]; Fenofibrate promotes the reaction [candesartan results in decreased expression of CD40LG protein] CTD PMID:16443859 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cdc25a cell division cycle 25A increases expression EXP Fenofibrate results in increased expression of CDC25A mRNA CTD PMID:17264098 NCBI chr 8:117,953,223...117,971,552
Ensembl chr 8:117,953,444...117,971,519
JBrowse link
G Cdk20 cyclin-dependent kinase 20 increases expression ISO Fenofibrate results in increased expression of CDK20 mRNA CTD PMID:25572481 NCBI chr17:1,935,900...1,942,867
Ensembl chr17:1,936,163...1,942,865
JBrowse link
G Cdk9 cyclin-dependent kinase 9 multiple interactions EXP Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein] CTD PMID:20828602 NCBI chr 3:11,742,269...11,747,117
Ensembl chr 3:11,742,266...11,747,113
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
decreases expression
EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CDKN1A mRNA
Fenofibrate results in decreased expression of CDKN1A mRNA
CTD PMID:18253720, PMID:25596134 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions
decreases expression
EXP
ISO
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CDKN1B mRNA
ESR1 protein inhibits the reaction [Fenofibrate results in decreased expression of CDKN1B protein]; Estradiol inhibits the reaction [Fenofibrate results in decreased expression of CDKN1B protein]
CTD PMID:18253720, PMID:29134746 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cers5 ceramide synthase 5 decreases expression EXP Fenofibrate results in decreased expression of CERS5 mRNA CTD PMID:25596134 NCBI chr 7:141,386,391...141,424,375
Ensembl chr 7:141,386,391...141,424,343
JBrowse link
G Ces1d carboxylesterase 1D multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CES1 mRNA CTD PMID:18253720 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Chek1 checkpoint kinase 1 increases expression EXP Fenofibrate results in increased expression of CHEK1 mRNA CTD PMID:17264098 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CHEK2 mRNA CTD PMID:18253720 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Chid1 chitinase domain containing 1 decreases expression ISO Fenofibrate results in decreased expression of CHID1 mRNA CTD PMID:11798191 NCBI chr 1:214,476,418...214,511,569
Ensembl chr 1:214,476,387...214,511,529
JBrowse link
G Chst8 carbohydrate sulfotransferase 8 multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CHST8 mRNA CTD PMID:18253720 NCBI chr 1:90,542,095...90,685,257
Ensembl chr 1:90,542,096...90,685,257
JBrowse link
G Cish cytokine inducible SH2-containing protein decreases expression
multiple interactions
ISO Fenofibrate results in decreased expression of CISH mRNA
PPARA protein affects the reaction [Fenofibrate results in decreased expression of CISH mRNA]
CTD PMID:21318169 NCBI chr 8:116,054,547...116,059,494
Ensembl chr 8:116,054,465...116,060,723
JBrowse link
G Cmbl carboxymethylenebutenolidase homolog increases expression EXP Fenofibrate results in increased expression of CMBL mRNA CTD PMID:25596134 NCBI chr 2:84,645,084...84,666,836
Ensembl chr 2:84,645,084...84,666,835
JBrowse link
G Cnot4 CCR4-NOT transcription complex, subunit 4 multiple interactions
increases expression
ISO PPARA protein affects the reaction [Fenofibrate results in increased expression of CNOT4 mRNA] CTD PMID:21318169 NCBI chr 4:62,561,443...62,663,225
Ensembl chr 4:62,561,444...62,663,200
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]
Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL1A1 mRNA]]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Fenofibrate inhibits the reaction [Zoledronic Acid results in increased expression of COL1A1 mRNA]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]]
CTD PMID:19593819, PMID:28871336, PMID:31016362 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions ISO Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL3A1 mRNA]]; Fenofibrate inhibits the reaction [Zoledronic Acid results in increased expression of COL3A1 mRNA] CTD PMID:28871336, PMID:31016362 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Col4a1 collagen type IV alpha 1 chain multiple interactions ISO Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of COL4A1 mRNA] CTD PMID:28871336 NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153
JBrowse link
G Colq collagen like tail subunit of asymmetric acetylcholinesterase increases expression EXP Fenofibrate results in increased expression of COLQ mRNA CTD PMID:27665778 NCBI chr16:7,626,380...7,681,621
Ensembl chr16:7,627,603...7,681,576
JBrowse link
G Coq7 coenzyme Q7, hydroxylase increases expression EXP Fenofibrate results in increased expression of COQ7 mRNA CTD PMID:16595124 NCBI chr 1:188,176,060...188,190,874
Ensembl chr 1:188,174,874...188,190,860
JBrowse link
G Cox6b2 cytochrome c oxidase subunit 6B2 increases expression ISO Fenofibrate results in increased expression of COX6B2 mRNA CTD PMID:11798191 NCBI chr 1:72,661,099...72,662,436
Ensembl chr 1:72,661,211...72,662,434
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression
multiple interactions
ISO
EXP
Fenofibrate results in increased expression of CPT1A mRNA
Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of CPT1A mRNA]
Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of CPT1A protein]; Fenofibrate promotes the reaction [Fatty Acids, Nonesterified results in increased expression of CPT1A mRNA]; Fenofibrate promotes the reaction [Oleic Acid results in increased expression of CPT1A mRNA]
CTD PMID:16595124, PMID:17070643, PMID:17118139, PMID:19124612, PMID:24534255, PMID:24735863, PMID:25572481, PMID:27665778, PMID:28871336 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B affects expression
multiple interactions
increases expression
EXP Fenofibrate affects the expression of CPT1B mRNA
Fenofibrate inhibits the reaction [Pyrazinamide results in decreased expression of CPT1B mRNA]
Fenofibrate results in increased expression of CPT1B mRNA
CTD PMID:16595124, PMID:19395589, PMID:20801182, PMID:27071702 NCBI chr 7:130,395,211...130,404,731
Ensembl chr 7:130,395,194...130,405,347
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 decreases expression
multiple interactions
increases expression
EXP
ISO
Fenofibrate results in decreased expression of CPT2 protein
Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of CPT2 mRNA]
Fenofibrate results in increased expression of CPT2 mRNA
[Oleic Acid co-treated with Fenofibrate] results in increased expression of CPT2 mRNA
CTD PMID:16595124, PMID:16707586, PMID:19395589, PMID:20118634, PMID:24534255, PMID:25572481, PMID:27665778, PMID:28871336 NCBI chr 5:127,505,646...127,523,016
Ensembl chr 5:127,505,614...127,523,089
JBrowse link
G Crat carnitine O-acetyltransferase increases expression
increases activity
multiple interactions
ISO
EXP
Fenofibrate results in increased expression of CRAT mRNA
Fenofibrate results in increased activity of CRAT protein
[Fenofibrate co-treated with Diethylnitrosamine] results in increased activity of CRAT protein; [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CRAT mRNA
CTD PMID:11798191, PMID:17264098, PMID:18253720, PMID:27665778 NCBI chr 3:8,967,984...8,981,959
Ensembl chr 3:8,968,417...8,981,362
JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 increases expression ISO Fenofibrate results in increased expression of CREB3L3 mRNA CTD PMID:25572481 NCBI chr 7:11,490,852...11,499,287
Ensembl chr 7:11,490,852...11,499,282
JBrowse link
G Crp C-reactive protein multiple interactions
decreases expression
ISO candesartan promotes the reaction [Fenofibrate results in decreased expression of CRP protein]; Fenofibrate promotes the reaction [candesartan results in decreased expression of CRP protein] CTD PMID:16123850, PMID:16443859 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Csf1r colony stimulating factor 1 receptor decreases expression EXP Fenofibrate results in decreased expression of CSF1R mRNA CTD PMID:16707586 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CSF2 mRNA CTD PMID:18253720 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Cth cystathionine gamma-lyase increases expression
decreases expression
ISO
EXP
Fenofibrate results in increased expression of CTH mRNA
Fenofibrate results in decreased expression of CTH mRNA
CTD PMID:25596134 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Ctsc cathepsin C decreases expression EXP Fenofibrate results in decreased expression of CTSC mRNA CTD PMID:25596134 NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 multiple interactions ISO Fenofibrate inhibits the reaction [Glucose results in increased expression of CX3CL1 mRNA]; Fenofibrate inhibits the reaction [Glucose results in increased expression of CX3CL1 protein] CTD PMID:19132243 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cyld CYLD lysine 63 deubiquitinase decreases expression
multiple interactions
ISO Fenofibrate results in decreased expression of CYLD mRNA
PPARA protein affects the reaction [Fenofibrate results in decreased expression of CYLD mRNA]
CTD PMID:21318169 NCBI chr19:19,264,984...19,323,817
Ensembl chr19:19,265,164...19,315,357
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP Fenofibrate results in increased expression of CYP1A1 mRNA CTD PMID:19118567 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
affects expression
EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP1A2 mRNA
Fenofibrate affects the expression of CYP1A2 mRNA
CTD PMID:18253720, PMID:20801182, PMID:25596134 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CYP2A3 mRNA CTD PMID:18253720 NCBI chr 1:83,653,248...83,662,118
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression ISO
EXP
Fenofibrate results in increased expression of CYP2B10 mRNA
Fenofibrate results in increased expression of CYP2B1 mRNA
CTD PMID:11798191, PMID:19118567 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CYP2B15 mRNA CTD PMID:18253720 NCBI chr 1:251,325,923...251,338,404
Ensembl chr 1:251,325,923...251,338,358
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO Fenofibrate results in increased expression of CYP2B9 mRNA CTD PMID:11798191 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP2C mRNA CTD PMID:18253720 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 increases expression ISO Fenofibrate results in increased expression of CYP2C19 mRNA CTD PMID:25572481 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp2c7 cytochrome P450, family 2, subfamily c, polypeptide 7 multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP2C7 mRNA CTD PMID:18253720 NCBI chr 1:147,422,999...148,119,979
Ensembl chr 1:148,053,687...148,119,857
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases activity
affects expression
increases expression
ISO Fenofibrate results in decreased activity of CYP2C8 protein
Fenofibrate affects the expression of CYP2C8 protein
Fenofibrate results in increased expression of CYP2C8 mRNA
CTD PMID:15601807, PMID:25572481, PMID:29960002 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP2D22 mRNA CTD PMID:18253720 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP Fenofibrate results in increased expression of CYP2E1 mRNA CTD PMID:19118567 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP2F2 mRNA CTD PMID:18253720 NCBI chr 1:83,933,974...83,947,804
Ensembl chr 1:83,933,942...83,947,821
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 affects expression ISO Fenofibrate affects the expression of CYP2J2 protein CTD PMID:29960002 NCBI chr 5:119,546,458...119,564,843
Ensembl chr 5:119,546,461...119,564,846
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP3A23-3A1 mRNA CTD PMID:18253720 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP3A13 mRNA CTD PMID:18253720 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 affects expression
increases expression
multiple interactions
EXP
ISO
Fenofibrate affects the expression of CYP4A1 mRNA
Fenofibrate results in increased expression of CYP4A12B mRNA
Fenofibrate results in increased expression of CYP4A22 mRNA
Fenofibrate results in increased expression of CYP4A1 mRNA
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CYP4A1 mRNA
CTD PMID:11798191, PMID:17264098, PMID:18775883, PMID:20801182, PMID:25572481, PMID:27665778 NCBI chr 5:134,492,734...134,507,158
Ensembl chr 5:134,492,756...134,507,154
JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 increases expression EXP Fenofibrate results in increased expression of CYP4A3 mRNA CTD PMID:27665778 NCBI chr 5:134,468,666...134,484,851
Ensembl chr 5:134,469,270...134,484,839
JBrowse link
G Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP4A8 mRNA CTD PMID:18253720 NCBI chr 5:133,978,953...134,008,255
Ensembl chr 5:133,978,954...134,008,255
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP4B1 mRNA CTD PMID:18253720 NCBI chr 5:134,508,728...134,526,103
Ensembl chr 5:134,508,730...134,526,089
JBrowse link
G Cyp4x1 cytochrome P450, family 4, subfamily x, polypeptide 1 increases expression ISO Fenofibrate results in increased expression of CYP4X1 mRNA CTD PMID:25572481 NCBI chr 5:133,929,532...133,959,447
Ensembl chr 5:133,929,532...133,959,447
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions
decreases expression
EXP
ISO
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP7A1 mRNA
Fenofibrate results in decreased expression of CYP7A1 mRNA
CTD PMID:14685799, PMID:18253720 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP7B1 mRNA CTD PMID:18253720 NCBI chr 2:102,701,903...102,871,257
Ensembl chr 2:102,701,903...102,871,257
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP8B1 mRNA CTD PMID:18253720 NCBI chr 8:130,548,418...130,550,388
Ensembl chr 8:130,548,418...130,550,388
JBrowse link
G Dact2 dishevelled-binding antagonist of beta-catenin 2 increases expression EXP Fenofibrate results in increased expression of DACT2 mRNA CTD PMID:27665778 NCBI chr 1:56,159,435...56,169,443
Ensembl chr 1:56,159,426...56,168,351
JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein increases expression ISO Fenofibrate results in increased expression of DBI mRNA CTD PMID:17118139 NCBI chr13:36,147,667...36,156,076
Ensembl chr13:36,117,119...36,174,908
JBrowse link
G Dcun1d1 defective in cullin neddylation 1 domain containing 1 increases expression ISO Fenofibrate results in increased expression of DCUN1D1 mRNA CTD PMID:21318169 NCBI chr 2:122,476,173...122,527,153
Ensembl chr 2:122,476,173...122,646,445
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Fenofibrate results in increased expression of DDIT3 mRNA CTD PMID:25596134 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 decreases expression
increases expression
ISO
EXP
Fenofibrate results in decreased expression of DDIT4 mRNA
Fenofibrate results in increased expression of DDIT4 mRNA
CTD PMID:25596134 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Ddx24 DEAD-box helicase 24 decreases expression EXP Fenofibrate results in decreased expression of DDX24 mRNA CTD PMID:25596134 NCBI chr 6:127,302,201...127,319,382
Ensembl chr 6:127,302,201...127,319,362
JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 increases expression
affects expression
ISO
EXP
Fenofibrate results in increased expression of DECR1 mRNA
Fenofibrate results in increased expression of DECR1 mRNA; Fenofibrate results in increased expression of DECR1 protein
Fenofibrate affects the expression of DECR1 mRNA
CTD PMID:11798191, PMID:20118634, PMID:20801182, PMID:27665778 NCBI chr 5:29,573,893...29,601,731
Ensembl chr 5:29,573,898...29,601,748
JBrowse link
G Decr2 2,4-dienoyl-CoA reductase 2 increases expression EXP Fenofibrate results in increased expression of DECR2 mRNA CTD PMID:27665778 NCBI chr10:15,451,850...15,460,227
Ensembl chr10:15,431,638...15,465,413
JBrowse link
G Dhx37 DEAH-box helicase 37 increases expression ISO Fenofibrate results in increased expression of DHX37 mRNA CTD PMID:25596134 NCBI chr12:36,594,058...36,614,165
Ensembl chr12:36,594,047...36,614,210
JBrowse link
G Dmd dystrophin decreases expression ISO Fenofibrate results in decreased expression of DMD mRNA CTD PMID:11798191 NCBI chr  X:51,149,358...53,519,271
Ensembl chr  X:51,286,737...53,519,259
JBrowse link
G Dnaja2 DnaJ heat shock protein family (Hsp40) member A2 multiple interactions
increases expression
EXP
ISO
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of DNAJA2 mRNA
Fenofibrate results in increased expression of DNAJA2 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJA2 mRNA]
CTD PMID:18253720, PMID:21318169 NCBI chr19:22,569,999...22,588,143
Ensembl chr19:22,569,999...22,588,137
JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 increases expression ISO Fenofibrate results in increased expression of DNAJA3 mRNA CTD PMID:21318169 NCBI chr10:11,059,701...11,085,186
Ensembl chr10:11,060,313...11,085,210
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of DNAJB1 mRNA CTD PMID:18253720 NCBI chr19:24,747,178...24,750,919
Ensembl chr19:24,747,178...24,750,919
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 decreases expression
multiple interactions
ISO Fenofibrate results in decreased expression of DNAJB4 mRNA
PPARA protein affects the reaction [Fenofibrate results in decreased expression of DNAJB4 mRNA]
CTD PMID:21318169 NCBI chr 2:257,394,692...257,425,344
Ensembl chr 2:257,394,818...257,425,242
JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of DNAJB6 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJB6 mRNA]
CTD PMID:21318169 NCBI chr 4:2,711,329...2,774,969
Ensembl chr 4:2,711,385...2,774,890
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 decreases expression EXP Fenofibrate results in decreased expression of DNAJB9 mRNA CTD PMID:25596134 NCBI chr 6:64,165,913...64,170,122
Ensembl chr 6:64,165,913...64,170,151
JBrowse link
G Dnajc14 DnaJ heat shock protein family (Hsp40) member C14 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of DNAJC14 mRNA
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC14 mRNA
CTD PMID:21318169 NCBI chr 7:3,229,026...3,242,265
Ensembl chr 7:3,230,320...3,242,265
JBrowse link
G Dnajc19 DnaJ heat shock protein family (Hsp40) member C19 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of DNAJC19 mRNA
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC19 mRNA
CTD PMID:21318169 NCBI chr 2:120,503,093...120,531,782
Ensembl chr 2:120,504,130...120,531,782
JBrowse link
G Dnajc2 DnaJ heat shock protein family (Hsp40) member C2 multiple interactions
increases expression
ISO [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC2 mRNA
Fenofibrate results in increased expression of DNAJC2 mRNA
CTD PMID:21318169 NCBI chr 4:9,881,505...9,908,693
Ensembl chr 4:9,882,904...9,908,689
JBrowse link
G Dnajc27 DnaJ heat shock protein family (Hsp40) member C27 decreases expression
multiple interactions
ISO Fenofibrate results in decreased expression of RBJ mRNA
PPARA protein affects the reaction [Fenofibrate results in decreased expression of RBJ mRNA]
CTD PMID:21318169 NCBI chr 6:28,515,054...28,544,756
Ensembl chr 6:28,515,025...28,544,790
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of DNAJC3 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJC3 mRNA]
CTD PMID:21318169 NCBI chr15:104,186,918...104,226,236
Ensembl chr15:104,186,792...104,226,329
JBrowse link
G Dnajc5 DnaJ heat shock protein family (Hsp40) member C5 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of DNAJC5 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJC5 mRNA]
CTD PMID:21318169 NCBI chr 3:177,012,714...177,047,787
Ensembl chr 3:177,013,604...177,043,902
JBrowse link
G Dnajc5b DnaJ heat shock protein family (Hsp40) member C5 beta increases expression EXP Fenofibrate results in increased expression of DNAJC5B mRNA CTD PMID:25596134 NCBI chr 2:104,290,726...104,382,846
Ensembl chr 2:104,290,726...104,382,878
JBrowse link
G Dnmbp dynamin binding protein decreases expression EXP Fenofibrate results in decreased expression of DNMBP mRNA CTD PMID:25596134 NCBI chr 1:263,625,503...263,718,784
Ensembl chr 1:263,625,501...263,718,745
JBrowse link
G Dusp5 dual specificity phosphatase 5 increases expression ISO Fenofibrate results in increased expression of DUSP5 mRNA CTD PMID:25596134 NCBI chr 1:274,245,184...274,258,595
Ensembl chr 1:274,245,184...274,258,595
JBrowse link
G Ech1 enoyl-CoA hydratase 1 affects expression
increases expression
EXP
ISO
Fenofibrate affects the expression of ECH1 mRNA
Fenofibrate results in increased expression of ECH1 mRNA; Fenofibrate results in increased expression of ECH1 protein
CTD PMID:11798191, PMID:17118139, PMID:20118634, PMID:20801182, PMID:27665778 NCBI chr 1:87,009,798...87,015,996
Ensembl chr 1:87,009,730...87,016,005
JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 increases expression ISO Fenofibrate results in increased expression of ECHS1 mRNA CTD PMID:24752549 NCBI chr 1:212,570,213...212,579,040
Ensembl chr 1:212,570,195...212,579,057
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 increases expression
affects expression
ISO
EXP
Fenofibrate results in increased expression of ECI1 mRNA
Fenofibrate affects the expression of ECI1 mRNA
CTD PMID:11798191, PMID:20801182, PMID:27665778 NCBI chr10:13,797,573...13,810,918
Ensembl chr10:13,797,562...13,810,913
JBrowse link
G Eci2 enoyl-CoA delta isomerase 2 increases expression EXP Fenofibrate results in increased expression of ECI2 mRNA CTD PMID:16707586 NCBI chr17:30,556,926...30,573,324
Ensembl chr17:30,556,884...30,639,040
JBrowse link
G Edn1 endothelin 1 multiple interactions EXP
ISO
EDN1 protein promotes the reaction [Fenofibrate promotes the reaction [NFATC4 protein binds to PPARA protein]]; Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]; Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to NPPB promoter]]; Fenofibrate inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]]
Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of EDN1 mRNA]
CTD PMID:22198280, PMID:31016362 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO Fenofibrate results in decreased expression of EGFR mRNA CTD PMID:11798191 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression
affects expression
ISO
EXP
Fenofibrate results in increased expression of EHHADH mRNA
Fenofibrate affects the expression of EHHADH mRNA
CTD PMID:11798191, PMID:17118139, PMID:20801182, PMID:27665778 NCBI chr11:82,945,104...82,978,364
Ensembl chr11:82,945,104...82,978,364
JBrowse link
G Eif1 eukaryotic translation initiation factor 1 decreases expression
increases expression
EXP
ISO
Fenofibrate results in decreased expression of EIF1 mRNA
Fenofibrate results in increased expression of EIF1 mRNA
CTD PMID:25596134 NCBI chr10:88,227,455...88,229,546
Ensembl chr10:88,227,360...88,229,765
JBrowse link
G Eif2s2 eukaryotic translation initiation factor 2 subunit beta affects expression EXP Fenofibrate affects the expression of EIF2S2 mRNA CTD PMID:25596134 NCBI chr 3:150,391,455...150,412,179
Ensembl chr 3:150,391,460...150,412,179
JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C increases expression EXP Fenofibrate results in increased expression of EIF3C mRNA CTD PMID:25596134 NCBI chr 1:197,964,406...197,982,917
Ensembl chr 1:197,964,407...197,982,601
JBrowse link
G Elk4 ETS transcription factor ELK4 increases expression ISO Fenofibrate results in increased expression of ELK4 mRNA CTD PMID:25596134 NCBI chr13:48,788,262...48,813,267
Ensembl chr13:48,790,509...48,813,260
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 multiple interactions
increases expression
ISO
EXP
[Oleic Acid co-treated with Fenofibrate] affects the expression of ELOVL6 mRNA
Fenofibrate results in increased expression of ELOVL6 mRNA
NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA]
CTD PMID:23063693, PMID:24534255, PMID:27665778 NCBI chr 2:234,187,490...234,296,124
Ensembl chr 2:234,189,105...234,296,145
Ensembl chr 2:234,189,105...234,296,145
JBrowse link
G Enc1 ectodermal-neural cortex 1 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of ENC1 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of ENC1 mRNA]
CTD PMID:21318169 NCBI chr 2:28,049,217...28,061,023
Ensembl chr 2:28,049,217...28,061,029
JBrowse link
G Eno1 enolase 1 increases expression ISO Fenofibrate results in increased expression of ENO1 mRNA CTD PMID:25596134 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 decreases expression ISO Fenofibrate results in decreased expression of ENPP2 mRNA CTD PMID:25572481 NCBI chr 7:94,479,931...94,563,086
Ensembl chr 7:94,480,396...94,563,001
JBrowse link
G Entpd7 ectonucleoside triphosphate diphosphohydrolase 7 decreases expression ISO Fenofibrate results in decreased expression of ENTPD7 mRNA CTD PMID:25596134 NCBI chr 1:263,448,633...263,490,308
Ensembl chr 1:263,448,633...263,490,308
Ensembl chr 1:263,448,633...263,490,308
JBrowse link
G Ep400 E1A binding protein p400 decreases expression EXP Fenofibrate results in decreased expression of EP400 mRNA CTD PMID:25596134 NCBI chr12:51,948,650...52,055,274
Ensembl chr12:51,948,650...52,055,271
JBrowse link
G Ephx2 epoxide hydrolase 2 affects expression EXP
ISO
Fenofibrate affects the expression of EPHX2 mRNA
Fenofibrate affects the expression of EPHX2 protein
CTD PMID:20801182, PMID:29960002 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Eprs glutamyl-prolyl-tRNA synthetase increases expression ISO
EXP
Fenofibrate results in increased expression of EPRS1 mRNA
Fenofibrate results in increased expression of EPRS mRNA
CTD PMID:25596134 NCBI chr13:103,300,911...103,371,651
Ensembl chr13:103,300,932...103,371,577
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression EXP Fenofibrate results in increased expression of ERO1A mRNA CTD PMID:25596134 NCBI chr15:19,619,947...19,655,381
Ensembl chr15:19,619,973...19,655,381
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO [ESR1 protein results in increased susceptibility to Estradiol] inhibits the reaction [Fenofibrate results in decreased expression of CASP3 protein]; ESR1 protein inhibits the reaction [Estradiol inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]]; ESR1 protein inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]; ESR1 protein inhibits the reaction [Fenofibrate results in decreased expression of CDKN1B protein]; ESR1 protein inhibits the reaction [Fenofibrate results in increased expression of CCND1 protein]; ESR1 protein inhibits the reaction [Fenofibrate results in increased expression of PCNA protein]; Estradiol inhibits the reaction [ESR1 protein inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]]; Estradiol inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]; Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein] CTD PMID:29134746 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Etfa electron transfer flavoprotein subunit alpha increases expression ISO Fenofibrate results in increased expression of ETFA mRNA CTD PMID:25572481 NCBI chr 8:60,028,786...60,086,352
Ensembl chr 8:60,028,789...60,086,403
JBrowse link
G Etfdh electron transfer flavoprotein dehydrogenase decreases expression
increases expression
EXP
ISO
Fenofibrate results in decreased expression of ETFDH protein
Fenofibrate results in increased expression of ETFDH mRNA
CTD PMID:20118634, PMID:25572481 NCBI chr 2:178,367,547...178,389,641
Ensembl chr 2:178,367,549...178,389,608
JBrowse link
G Etnk2 ethanolamine kinase 2 decreases expression ISO Fenofibrate results in decreased expression of ETNK2 mRNA CTD PMID:25572481 NCBI chr13:50,481,178...50,498,991
Ensembl chr13:50,481,163...50,499,140
JBrowse link
G F2 coagulation factor II multiple interactions ISO Fenofibrate promotes the reaction [Warfarin results in decreased expression of F2 protein] CTD PMID:9681093 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G F7 coagulation factor VII multiple interactions ISO Fenofibrate promotes the reaction [Warfarin results in decreased expression of F7 protein] CTD PMID:9681093 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945
JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression
multiple interactions
ISO
EXP
Fenofibrate results in increased expression of FABP1 mRNA
Fenofibrate inhibits the reaction [Pyrazinamide results in decreased expression of FABP1 mRNA]
CTD PMID:17118139, PMID:24752549, PMID:27071702 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954
JBrowse link
G Fabp2 fatty acid binding protein 2 increases expression ISO Fenofibrate results in increased expression of FABP2 mRNA CTD PMID:17118139 NCBI chr 2:227,080,912...227,083,654
Ensembl chr 2:227,080,924...227,083,501
JBrowse link
G Fabp3 fatty acid binding protein 3 increases expression EXP Fenofibrate results in increased expression of FABP3 mRNA CTD PMID:25596134 NCBI chr 5:148,528,854...148,535,597
Ensembl chr 5:148,528,725...148,535,565
JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression ISO Fenofibrate results in increased expression of FABP4 mRNA CTD PMID:11798191, PMID:12759900, PMID:25572481 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fads1 fatty acid desaturase 1 multiple interactions
increases expression
ISO beta-hydroxy simvastatin acid promotes the reaction [Fenofibrate results in increased expression of FADS1 mRNA]; Fenofibrate promotes the reaction [beta-hydroxy simvastatin acid results in increased expression of FADS1 mRNA] CTD PMID:17655842 NCBI chr 1:226,234,034...226,249,118
Ensembl chr 1:226,234,074...226,249,138
JBrowse link
G Fah fumarylacetoacetate hydrolase increases expression ISO Fenofibrate results in increased expression of FAH mRNA CTD PMID:25572481 NCBI chr 1:146,713,663...146,736,339
Ensembl chr 1:146,713,676...146,736,261
JBrowse link
G Fam210a family with sequence similarity 210, member A affects expression EXP Fenofibrate affects the expression of FAM210A mRNA CTD PMID:25596134 NCBI chr18:64,045,023...64,084,594
Ensembl chr18:64,045,432...64,084,556
JBrowse link
G Fam214a family with sequence similarity 214, member A decreases expression EXP Fenofibrate results in decreased expression of FAM214A mRNA CTD PMID:25596134 NCBI chr 8:81,863,619...81,941,548
Ensembl chr 8:81,863,619...81,941,536
JBrowse link
G Fam222a family with sequence similarity 222, member A increases expression ISO Fenofibrate results in increased expression of FAM222A mRNA CTD PMID:25572481 NCBI chr12:47,742,449...47,793,534
Ensembl chr12:47,748,165...47,793,534
JBrowse link
G Fam241a family with sequence similarity 241 member A increases expression ISO Fenofibrate results in increased expression of FAM241A mRNA CTD PMID:25572481 NCBI chr 2:232,214,331...232,245,319
Ensembl chr 2:232,214,331...232,245,319
JBrowse link
G Fam89a family with sequence similarity 89, member A increases expression ISO Fenofibrate results in increased expression of FAM89A mRNA CTD PMID:25596134 NCBI chr19:57,502,308...57,514,896
Ensembl chr19:57,502,308...57,514,896
JBrowse link
G Fas Fas cell surface death receptor multiple interactions
decreases expression
ISO
EXP
Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of FAS mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of FAS mRNA]]
Fenofibrate results in decreased expression of FAS mRNA
CTD PMID:19593819, PMID:25596134 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fasn fatty acid synthase multiple interactions
increases expression
ISO
EXP
[Oleic Acid co-treated with Fenofibrate] affects the expression of FASN mRNA
[Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in increased expression of FASN mRNA]; Fenofibrate inhibits the reaction [Fructose results in increased expression of FASN mRNA]
Fenofibrate results in increased expression of FASN mRNA
NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]
CTD PMID:17118139, PMID:23063693, PMID:24534255, PMID:26973390 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fbxo21 F-box protein 21 increases expression ISO Fenofibrate results in increased expression of FBXO21 mRNA CTD PMID:21318169 NCBI chr12:44,244,633...44,279,044
Ensembl chr12:44,246,508...44,279,002
JBrowse link
G Fbxo22 F-box protein 22 decreases expression EXP Fenofibrate results in decreased expression of FBXO22 mRNA CTD PMID:25596134 NCBI chr 8:59,770,032...59,786,061
Ensembl chr 8:59,769,994...59,786,065
JBrowse link
G Fbxo3 F-box protein 3 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of FBXO3 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO3 mRNA]
CTD PMID:21318169 NCBI chr 3:93,968,827...94,000,863
Ensembl chr 3:93,968,855...94,000,863
JBrowse link
G Fbxo30 F-box protein 30 increases expression
multiple interactions
ISO
EXP
Fenofibrate results in increased expression of FBXO30 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO30 mRNA]
CTD PMID:21318169, PMID:25596134 NCBI chr 1:5,366,119...5,389,774
Ensembl chr 1:5,366,379...5,388,069
JBrowse link
G Fbxo36 F-box protein 36 decreases expression ISO Fenofibrate results in decreased expression of FBXO36 mRNA CTD PMID:21318169 NCBI chr 9:92,435,872...92,500,765
Ensembl chr 9:92,435,896...92,500,765
JBrowse link
G Fbxo9 f-box protein 9 increases expression ISO Fenofibrate results in increased expression of FBXO9 mRNA CTD PMID:21318169 NCBI chr 8:85,388,331...85,413,896
Ensembl chr 8:85,388,333...85,413,484
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of FDFT1 mRNA
NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FDFT1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FDFT1 mRNA]
CTD PMID:23063693 NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
JBrowse link
G Fga fibrinogen alpha chain multiple interactions
decreases expression
ISO
EXP
PPARA promotes the reaction [Fenofibrate results in decreased expression of FGA mRNA] CTD PMID:10216095 NCBI chr 2:181,997,562...182,013,726
Ensembl chr 2:182,006,242...182,013,763
JBrowse link
G Fgb fibrinogen beta chain decreases expression EXP Fenofibrate results in decreased expression of FGB mRNA CTD PMID:10216095 NCBI chr 2:182,028,044...182,035,026
Ensembl chr 2:182,027,115...182,038,178
JBrowse link
G Fgf21 fibroblast growth factor 21 increases expression ISO Fenofibrate results in increased expression of FGF21 mRNA; Fenofibrate results in increased expression of FGF21 protein CTD PMID:22338096 NCBI chr 1:101,595,579...101,596,822
Ensembl chr 1:101,595,579...101,596,822
JBrowse link
G Fgg fibrinogen gamma chain decreases expression EXP Fenofibrate results in decreased expression of FGG mRNA CTD PMID:10216095 NCBI chr 2:181,987,080...181,994,523
Ensembl chr 2:181,987,217...181,994,514
JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase affects expression EXP Fenofibrate affects the expression of FGR mRNA CTD PMID:25596134 NCBI chr 5:151,172,189...151,199,746
Ensembl chr 5:151,172,206...151,199,745
JBrowse link
G Fkbp15 FKBP prolyl isomerase family member 15 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of FKBP15 mRNA
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of FKBP15 mRNA
CTD PMID:21318169 NCBI chr 5:78,133,357...78,229,311
Ensembl chr 5:78,133,886...78,183,122
JBrowse link
G Fkbp8 FKBP prolyl isomerase 8 increases expression ISO Fenofibrate results in increased expression of FKBP8 mRNA CTD PMID:21318169 NCBI chr16:20,645,956...20,652,890
Ensembl chr16:20,645,957...20,652,889
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of FMO1 mRNA CTD PMID:18253720 NCBI chr13:80,712,885...80,745,095
Ensembl chr13:80,712,882...80,745,347
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 multiple interactions
decreases expression
EXP
ISO
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of FMO5 mRNA
Fenofibrate results in decreased expression of FMO5 mRNA
CTD PMID:18253720, PMID:25572481 NCBI chr 2:199,796,870...199,823,927
Ensembl chr 2:199,796,881...199,823,927
JBrowse link
G Fn1 fibronectin 1 affects expression
multiple interactions
EXP
ISO
Fenofibrate affects the expression of FN1 mRNA
Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of FN1 protein]
CTD PMID:20801182, PMID:28871336 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Foxq1 forkhead box Q1 decreases expression ISO Fenofibrate results in decreased expression of FOXQ1 mRNA CTD PMID:11798191 NCBI chr17:34,224,308...34,226,941
Ensembl chr17:34,224,818...34,226,453
JBrowse link
G G6pc glucose-6-phosphatase, catalytic subunit decreases expression ISO Fenofibrate results in decreased expression of G6PC mRNA CTD PMID:25572481 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha multiple interactions
increases expression
EXP [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of GADD45A mRNA
Fenofibrate results in increased expression of GADD45A mRNA
CTD PMID:17264098, PMID:18253720, PMID:18775883, PMID:25596134 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GADD45B mRNA CTD PMID:18253720 NCBI chr 7:11,646,283...11,648,338
Ensembl chr 7:11,646,269...11,648,322
JBrowse link
G Galt galactose-1-phosphate uridylyltransferase increases expression ISO Fenofibrate results in increased expression of GALT mRNA CTD PMID:25572481 NCBI chr 5:58,144,679...58,147,946
Ensembl chr 5:58,144,705...58,147,929
JBrowse link
G Gars glycyl-tRNA synthetase increases expression ISO Fenofibrate results in increased expression of GARS1 mRNA CTD PMID:25596134 NCBI chr 4:85,235,122...85,276,085
Ensembl chr 4:85,235,172...85,276,044
JBrowse link
G Gata4 GATA binding protein 4 multiple interactions EXP Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]] CTD PMID:22198280 NCBI chr15:46,386,703...46,458,679
Ensembl chr15:46,386,712...46,432,965
JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 decreases expression
increases expression
EXP
ISO
Fenofibrate results in decreased expression of GBE1 mRNA
Fenofibrate results in increased expression of GBE1 mRNA
CTD PMID:25596134 NCBI chr11:7,210,169...7,485,895
Ensembl chr11:7,210,209...7,485,890
JBrowse link
G Gcat glycine C-acetyltransferase decreases expression ISO Fenofibrate results in decreased expression of GCAT mRNA CTD PMID:25572481 NCBI chr 7:120,263,068...120,269,365
Ensembl chr 7:120,263,054...120,269,451
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression EXP Fenofibrate results in decreased expression of GCLC mRNA CTD PMID:25596134 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Fenofibrate results in increased expression of GCLM mRNA CTD PMID:25596134 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type increases expression ISO Fenofibrate results in increased expression of GCNT3 mRNA CTD PMID:25596134 NCBI chr 8:76,449,078...76,459,431
Ensembl chr 8:76,449,081...76,452,554
JBrowse link
G Gde1 glycerophosphodiester phosphodiesterase 1 affects expression EXP Fenofibrate affects the expression of GDE1 mRNA CTD PMID:20801182 NCBI chr 1:188,367,550...188,407,125
Ensembl chr 1:188,394,814...188,407,132
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO
EXP
Fenofibrate results in increased expression of GDF15 mRNA CTD PMID:25596134 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gk glycerol kinase increases expression ISO Fenofibrate results in increased expression of GK mRNA CTD PMID:25572481 NCBI chr  X:54,227,291...54,303,897
Ensembl chr  X:54,227,397...54,303,864
JBrowse link
G Gnmt glycine N-methyltransferase decreases expression ISO Fenofibrate results in decreased expression of GNMT mRNA CTD PMID:25572481 NCBI chr 9:16,565,274...16,568,626
Ensembl chr 9:16,565,225...16,568,627
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 increases expression EXP Fenofibrate results in increased expression of GOT1 mRNA CTD PMID:25596134 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 increases expression EXP Fenofibrate results in increased expression of GOT2 mRNA CTD PMID:19652460 NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial increases expression EXP Fenofibrate results in increased expression of GPAM mRNA CTD PMID:16707586 NCBI chr 1:275,843,823...275,906,880
Ensembl chr 1:275,846,819...275,906,686
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO Fenofibrate results in increased expression of GPAT3 mRNA CTD PMID:25596134 NCBI chr14:10,343,287...10,396,565
Ensembl chr14:10,343,282...10,395,047
JBrowse link
G Gphn gephyrin increases expression EXP
ISO
Fenofibrate results in increased expression of GPHN mRNA CTD PMID:25596134 NCBI chr 6:101,327,874...101,859,169
Ensembl chr 6:101,532,518...101,859,164
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP Fenofibrate inhibits the reaction [Pyrazinamide results in increased expression of GPT protein] CTD PMID:27071702 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX1 mRNA] CTD PMID:31241159 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions
increases expression
EXP
ISO
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of GPX2 mRNA
Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX2 mRNA]
Fenofibrate results in increased expression of GPX2 mRNA
CTD PMID:17264098, PMID:18253720, PMID:18775883, PMID:31241159 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Gpx3 glutathione peroxidase 3 multiple interactions ISO Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX3 mRNA] CTD PMID:31241159 NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422
JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions ISO Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX4 mRNA] CTD PMID:31241159 NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154
JBrowse link
G Grm3 glutamate metabotropic receptor 3 increases expression ISO Fenofibrate results in increased expression of GRM3 mRNA CTD PMID:25572481 NCBI chr 4:21,316,761...21,567,561
Ensembl chr 4:21,317,695...21,560,490
JBrowse link
G Grpel2 GrpE-like 2, mitochondrial increases expression
multiple interactions
ISO Fenofibrate results in increased expression of GRPEL2 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of GRPEL2 mRNA]
CTD PMID:21318169 NCBI chr18:57,037,995...57,050,234
Ensembl chr18:57,036,877...57,050,408
JBrowse link
G Gsr glutathione-disulfide reductase increases expression EXP Fenofibrate results in increased expression of GSR mRNA CTD PMID:25596134 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 decreases expression
multiple interactions
EXP Fenofibrate results in decreased expression of GSTA2 mRNA
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GSTA2 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GSTA3 mRNA
CTD PMID:18253720, PMID:18775883 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta5 glutathione S-transferase alpha 5 multiple interactions
increases expression
EXP [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA
Fenofibrate results in increased expression of GSTA5 mRNA
CTD PMID:17264098, PMID:18253720, PMID:18775883 NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179
JBrowse link
G Gstm2 glutathione S-transferase mu 2 multiple interactions
decreases expression
EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GSTM2 mRNA
Fenofibrate results in decreased expression of GSTM2 mRNA
CTD PMID:18253720, PMID:18775883 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 multiple interactions
decreases expression
EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GSTM3 mRNA
Fenofibrate results in decreased expression of GSTM3 mRNA
CTD PMID:18253720, PMID:18775883 NCBI chr 2:210,685,338...210,688,133
Ensembl chr 2:210,685,197...210,688,272
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Fenofibrate inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G H1f2 H1.2 linker histone, cluster member decreases expression ISO Fenofibrate results in decreased expression of H1-2 mRNA CTD PMID:25596134 NCBI chr17:43,638,938...43,640,445
Ensembl chr17:43,639,749...43,640,387
JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase increases expression ISO Fenofibrate results in increased expression of HADH mRNA CTD PMID:24752549 NCBI chr 2:236,353,445...236,395,067
Ensembl chr 2:236,353,445...236,395,067
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha increases expression
decreases expression
ISO
EXP
Fenofibrate results in increased expression of HADHA mRNA
Fenofibrate results in decreased expression of HADHA protein
CTD PMID:16707586, PMID:17118139, PMID:20118634, PMID:25572481 NCBI chr 6:27,589,840...27,628,921
Ensembl chr 6:27,589,657...27,629,175
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta increases expression
decreases expression
affects expression
ISO
EXP
Fenofibrate results in increased expression of HADHB mRNA
Fenofibrate results in decreased expression of HADHB protein
Fenofibrate affects the expression of HADHB mRNA
CTD PMID:17118139, PMID:20118634, PMID:20801182, PMID:24752549, PMID:25572481 NCBI chr 6:27,555,408...27,589,539
Ensembl chr 6:27,555,412...27,582,995
JBrowse link
G Hdgfl3 HDGF like 3 increases expression EXP Fenofibrate results in increased expression of HDGFL3 mRNA CTD PMID:17264098 NCBI chr 1:143,702,864...143,752,060
Ensembl chr 1:143,702,853...143,751,789
JBrowse link
G Hectd1 HECT domain E3 ubiquitin protein ligase 1 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of HECTD1 mRNA
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of HECTD1 mRNA
CTD PMID:21318169 NCBI chr 6:72,509,658...72,596,285
Ensembl chr 6:72,510,255...72,596,446
JBrowse link
G Herc3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 increases expression ISO Fenofibrate results in increased expression of HERC3 mRNA CTD PMID:25596134 NCBI chr 4:89,078,670...89,169,150
Ensembl chr 4:89,078,711...89,169,146
JBrowse link
G Hes1 hes family bHLH transcription factor 1 multiple interactions ISO Fenofibrate inhibits the reaction [triptolide results in increased expression of HES1 mRNA] CTD PMID:31241159 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression
affects activity
ISO
EXP
Fenofibrate results in increased expression of HIF1A mRNA
Fenofibrate affects the activity of HIF1A protein
CTD PMID:17118139, PMID:25596134 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression
decreases expression
multiple interactions
ISO
EXP
Fenofibrate results in increased expression of HMGCR mRNA
Fenofibrate results in decreased expression of HMGCR mRNA
NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of HMGCR mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of HMGCR mRNA]
CTD PMID:16595124, PMID:23063693 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Fenofibrate results in increased expression of HMGCS1 mRNA CTD PMID:11798191 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 increases expression ISO
EXP
Fenofibrate results in increased expression of HMGCS2 mRNA CTD PMID:25572481, PMID:27665778 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423
JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP
ISO
Fenofibrate results in increased expression of HMOX1 mRNA CTD PMID:25596134 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hoga1 4-hydroxy-2-oxoglutarate aldolase 1 decreases expression ISO Fenofibrate results in decreased expression of HOGA1 mRNA CTD PMID:25572481 NCBI chr 1:261,291,742...261,319,743
Ensembl chr 1:261,291,870...261,318,984
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of HRAS mRNA CTD PMID:18978307 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 increases expression ISO Fenofibrate results in increased expression of HSD11B1 mRNA CTD PMID:25572481 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 increases expression ISO Fenofibrate results in increased expression of HSD17B4 mRNA CTD PMID:17118139, PMID:25572481 NCBI chr18:44,810,462...44,897,677
Ensembl chr18:44,810,388...44,897,640
JBrowse link
G Hsf1 heat shock transcription factor 1 multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of HSF1 mRNA CTD PMID:18253720 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of HSP90AA1 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of HSP90AA1 mRNA]
CTD PMID:21318169 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 multiple interactions
increases expression
ISO PPARA protein affects the reaction [Fenofibrate results in increased expression of HSP90AB1 mRNA] CTD PMID:21318169 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 increases expression ISO Fenofibrate results in increased expression of HSP90B1 mRNA CTD PMID:21318169 NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533
JBrowse link
G Hspa13 heat shock protein family A (Hsp70) member 13 decreases expression
multiple interactions
ISO Fenofibrate results in decreased expression of STCH mRNA
PPARA protein affects the reaction [Fenofibrate results in decreased expression of STCH mRNA]
CTD PMID:21318169 NCBI chr11:14,146,515...14,160,697
Ensembl chr11:14,144,130...14,160,892
JBrowse link
G Hspa4l heat shock protein family A (Hsp70) member 4 like increases expression
multiple interactions
ISO Fenofibrate results in increased expression of HSPA4L mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA4L mRNA]
CTD PMID:21318169 NCBI chr 2:127,625,737...127,682,864
Ensembl chr 2:127,625,683...127,677,503
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression EXP Fenofibrate results in decreased expression of HSPA5 mRNA CTD PMID:25596134 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of HSPA8 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA8 mRNA]
CTD PMID:21318169 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of HSPA9 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA9 mRNA]
CTD PMID:21318169 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 affects expression
multiple interactions
increases expression
EXP
ISO
Fenofibrate affects the expression of HSPB1 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPB1 mRNA]
CTD PMID:20801182, PMID:21318169 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Hspb8 heat shock protein family B (small) member 8 multiple interactions
increases expression
ISO [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of HSPB8 mRNA
Fenofibrate results in increased expression of HSPB8 mRNA
CTD PMID:21318169 NCBI chr12:45,905,371...45,920,014
Ensembl chr12:45,905,371...45,920,013
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 affects expression EXP Fenofibrate affects the expression of HSPE1 mRNA CTD PMID:20801182 NCBI chr 9:61,691,246...61,724,948
Ensembl chr 9:61,692,154...61,694,599
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of HSPH1 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPH1 mRNA]
CTD PMID:21318169 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 increases expression EXP Fenofibrate results in increased expression of HTATIP2 mRNA CTD PMID:25596134 NCBI chr 1:105,094,272...105,109,459
Ensembl chr 1:105,094,411...105,109,461
JBrowse link
G Iars1 isoleucyl-tRNA synthetase 1 increases expression EXP
ISO
Fenofibrate results in increased expression of IARS1 mRNA CTD PMID:25596134 NCBI chr17:15,356,016...15,402,680
Ensembl chr17:15,355,529...15,402,649
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]
dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of ICAM1 mRNA]]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of ICAM1 mRNA]
CTD PMID:20580385, PMID:21300114 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Id2 inhibitor of DNA binding 2 decreases expression ISO Fenofibrate results in decreased expression of ID2 mRNA CTD PMID:11798191 NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915
JBrowse link
G Idh3b isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta increases expression ISO Fenofibrate results in increased expression of IDH3B mRNA CTD PMID:24752549 NCBI chr 3:122,808,564...122,813,638
Ensembl chr 3:122,808,564...122,813,583
JBrowse link
G Iffo1 intermediate filament family orphan 1 increases expression EXP Fenofibrate results in increased expression of IFFO1 mRNA CTD PMID:16707586 NCBI chr 4:157,659,115...157,676,335
Ensembl chr 4:157,659,147...157,676,331
JBrowse link
G Ifng interferon gamma multiple interactions EXP Fenofibrate results in decreased susceptibility to [IFNG protein co-treated with IL1B protein] CTD PMID:20631892 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf2r insulin-like growth factor 2 receptor decreases expression EXP Fenofibrate results in decreased expression of IGF2R mRNA CTD PMID:25596134 NCBI chr 1:48,176,095...48,264,482
Ensembl chr 1:48,176,106...48,264,477
JBrowse link
G Il12b interleukin 12B multiple interactions ISO Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:15968640 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il17rb interleukin 17 receptor B decreases expression EXP Fenofibrate results in decreased expression of IL17RB mRNA CTD PMID:25596134 NCBI chr16:6,064,287...6,077,978
Ensembl chr16:6,064,288...6,077,978
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP
[Fenofibrate co-treated with Alitretinoin] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Fenofibrate inhibits the reaction [triptolide results in increased expression of IL1B mRNA]
Fenofibrate results in decreased susceptibility to [IFNG protein co-treated with IL1B protein]
CTD PMID:15968640, PMID:20631892, PMID:21300114, PMID:31241159 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions
affects response to substance
ISO [Fenofibrate co-treated with Alitretinoin] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 mRNA]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of IL6 mRNA]; Fenofibrate inhibits the reaction [triptolide results in increased expression of IL6 mRNA]; Fenofibrate promotes the reaction [Dextran Sulfate results in increased expression of IL6 protein]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of IL6 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 mRNA]]
IL6 promoter polymorphism affects the susceptibility to Fenofibrate
CTD PMID:15968640, PMID:16607077, PMID:19593819, PMID:21300114, PMID:25035112, PMID:31241159 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Insig1 insulin induced gene 1 decreases expression ISO Fenofibrate results in decreased expression of INSIG1 mRNA CTD PMID:25572481 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Insig2 insulin induced gene 2 decreases expression EXP Fenofibrate results in decreased expression of INSIG2 mRNA CTD PMID:25596134 NCBI chr13:37,264,818...37,292,718
Ensembl chr13:37,266,312...37,287,458
JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 increases expression ISO Fenofibrate results in increased expression of IRAK2 mRNA CTD PMID:25572481 NCBI chr 4:145,594,575...145,651,066
Ensembl chr 4:145,594,575...145,651,053
JBrowse link
G Irf7 interferon regulatory factor 7 increases expression ISO Fenofibrate results in increased expression of IRF7 mRNA CTD PMID:25572481 NCBI chr 1:214,249,388...214,252,909
Ensembl chr 1:214,248,837...214,252,456
JBrowse link
G Itch itchy E3 ubiquitin protein ligase multiple interactions
decreases expression
ISO PPARA protein affects the reaction [Fenofibrate results in decreased expression of ITCH mRNA] CTD PMID:21318169 NCBI chr 3:150,660,665...150,752,016
Ensembl chr 3:150,686,638...150,749,827
JBrowse link
G Itfg2 integrin alpha FG-GAP repeat containing 2 increases expression ISO Fenofibrate results in increased expression of ITFG2 mRNA CTD PMID:25596134 NCBI chr 4:161,730,643...161,744,281
Ensembl chr 4:161,730,641...161,743,896
JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression EXP Fenofibrate results in decreased expression of ITGB1 mRNA CTD PMID:25596134 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Itgb3 integrin subunit beta 3 affects expression EXP Fenofibrate affects the expression of ITGB3 mRNA CTD PMID:20801182 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Fenofibrate inhibits the reaction [Glucose results in increased expression of JUN protein]
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of JUN mRNA; Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of JUN mRNA]
CTD PMID:16600694, PMID:18978307, PMID:31016362 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kcnk13 potassium two pore domain channel subfamily K member 13 increases expression ISO Fenofibrate results in increased expression of KCNK13 mRNA CTD PMID:25572481, PMID:25596134 NCBI chr 6:123,971,030...124,077,249
Ensembl chr 6:123,974,798...124,077,197
JBrowse link
G Klf10 Kruppel-like factor 10 decreases expression
increases expression
ISO Fenofibrate results in decreased expression of KLF10 mRNA
Fenofibrate results in increased expression of KLF10 mRNA
CTD PMID:11798191, PMID:25572481 NCBI chr 7:77,156,010...77,162,096
Ensembl chr 7:77,156,006...77,162,148
JBrowse link
G Klf11 Kruppel-like factor 11 increases expression ISO Fenofibrate results in increased expression of KLF11 mRNA CTD PMID:25572481 NCBI chr 6:43,829,812...43,841,649
Ensembl chr 6:43,829,945...43,841,651
JBrowse link
G Krt18 keratin 18 multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of KRT18 protein CTD PMID:18978307 NCBI chr 7:143,629,455...143,633,131
Ensembl chr 7:143,629,455...143,633,131
JBrowse link
G Krt8 keratin 8 multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of KRT8 protein CTD PMID:18978307 NCBI chr 7:143,596,511...143,603,745
Ensembl chr 7:143,596,511...143,603,803
JBrowse link
G Lama4 laminin subunit alpha 4 increases expression ISO Fenofibrate results in increased expression of LAMA4 mRNA CTD PMID:25572481 NCBI chr20:44,060,715...44,201,966
Ensembl chr20:44,060,731...44,209,614
JBrowse link
G Lars1 leucyl-tRNA synthetase 1 decreases expression
increases expression
EXP
ISO
Fenofibrate results in decreased expression of LARS mRNA
Fenofibrate results in increased expression of LARS1 mRNA
CTD PMID:25596134 NCBI chr18:36,524,013...36,579,471
Ensembl chr18:36,524,007...36,579,403
JBrowse link
G Lbh LBH regulator of WNT signaling pathway increases expression ISO Fenofibrate results in increased expression of LBH mRNA CTD PMID:25572481 NCBI chr 6:24,154,207...24,184,217
Ensembl chr 6:24,160,226...24,181,866
JBrowse link
G Ldhb lactate dehydrogenase B increases expression ISO Fenofibrate results in increased expression of LDHB mRNA CTD PMID:25572481 NCBI chr 4:176,701,980...176,719,999
Ensembl chr 4:176,701,983...176,720,012
JBrowse link
G Lep leptin multiple interactions EXP [Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in increased expression of LEP mRNA]; Fenofibrate inhibits the reaction [Fructose results in increased expression of LEP mRNA] CTD PMID:26973390 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lgals1 galectin 1 increases expression ISO Fenofibrate results in increased expression of LGALS1 mRNA CTD PMID:11798191 NCBI chr 7:120,153,184...120,156,290
Ensembl chr 7:120,153,184...120,156,289
JBrowse link
G Lifr LIF receptor subunit alpha decreases expression ISO Fenofibrate results in decreased expression of LIFR mRNA CTD PMID:11798191 NCBI chr 2:56,424,910...56,489,346
Ensembl chr 2:56,426,367...56,489,415
JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 affects expression EXP Fenofibrate affects the expression of LMCD1 mRNA CTD PMID:25596134 NCBI chr 4:144,192,989...144,252,554
Ensembl chr 4:144,192,989...144,252,551
JBrowse link
G Lnx1 ligand of numb-protein X 1 multiple interactions
decreases expression
ISO PPARA protein affects the reaction [Fenofibrate results in decreased expression of LNX1 mRNA] CTD PMID:21318169 NCBI chr14:36,047,136...36,149,740
Ensembl chr14:36,047,144...36,149,740
JBrowse link
G LOC100364500 RT1 class I, locus CE11-like affects response to substance ISO HLA-A gene polymorphism affects the susceptibility to Fenofibrate CTD PMID:28043905 NCBI chr20:2,704,153...2,707,111
Ensembl chr20:2,704,148...2,707,120
JBrowse link
G LOC100365958 Rdh2 protein-like increases expression ISO Fenofibrate results in increased expression of RDH16 mRNA CTD PMID:11798191 NCBI chr 7:71,065,077...71,074,128
Ensembl chr 7:70,980,422...71,072,689
JBrowse link
G LOC690000 similar to CG3740-PA increases expression ISO Fenofibrate results in increased expression of C19ORF12 mRNA CTD PMID:25572481 NCBI chr 1:94,572,714...94,587,842
Ensembl chr 1:94,579,080...94,587,219
JBrowse link
G Lpcat2 lysophosphatidylcholine acyltransferase 2 increases expression ISO Fenofibrate results in increased expression of LPCAT2 mRNA CTD PMID:25572481 NCBI chr19:15,470,177...15,540,704
Ensembl chr19:15,469,303...15,540,773
JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 increases expression ISO Fenofibrate results in increased expression of LPCAT3 mRNA CTD PMID:25572481 NCBI chr 4:157,181,722...157,222,997
Ensembl chr 4:157,181,795...157,222,996
JBrowse link
G Lpl lipoprotein lipase increases expression
multiple interactions
increases activity
ISO
EXP
Fenofibrate results in increased expression of LPL mRNA; Fenofibrate results in increased expression of LPL protein
PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LPL mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LPL protein]
PPARA protein promotes the reaction [Fenofibrate results in increased expression of LPL protein]
Fenofibrate inhibits the reaction [Pyrazinamide results in decreased expression of LPL mRNA]
Fenofibrate results in increased activity of LPL protein
CTD PMID:8593127, PMID:11798191, PMID:16595124, PMID:24752549, PMID:27071702 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Lrrc31 leucine rich repeat containing 31 increases expression ISO Fenofibrate results in increased expression of LRRC31 mRNA CTD PMID:25572481 NCBI chr 2:116,299,380...116,343,089
Ensembl chr 2:116,313,591...116,344,137
JBrowse link
G Lrsam1 leucine rich repeat and sterile alpha motif containing 1 multiple interactions
decreases expression
ISO PPARA protein affects the reaction [Fenofibrate results in decreased expression of LRSAM1 mRNA] CTD PMID:21318169 NCBI chr 3:11,970,401...12,009,463
Ensembl chr 3:11,972,813...12,007,570
JBrowse link
G Lss lanosterol synthase increases expression
multiple interactions
ISO Fenofibrate results in increased expression of LSS mRNA
NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LSS mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LSS mRNA]
CTD PMID:23063693 NCBI chr20:12,844,522...12,870,474
Ensembl chr20:12,842,884...12,870,497
JBrowse link
G Ltn1 listerin E3 ubiquitin protein ligase 1 decreases expression EXP Fenofibrate results in decreased expression of LTN1 mRNA CTD PMID:25596134 NCBI chr11:27,023,328...27,080,575
Ensembl chr11:27,022,986...27,080,701
JBrowse link
G Ly6d lymphocyte antigen 6 family member D increases expression ISO Fenofibrate results in increased expression of LY6D mRNA CTD PMID:17118139 NCBI chr 7:115,993,304...115,994,812
Ensembl chr 7:115,993,301...115,994,783
JBrowse link
G Lyrm1 LYR motif containing 1 increases expression ISO Fenofibrate results in increased expression of LYRM1 mRNA CTD PMID:25572481 NCBI chr 1:189,665,401...189,685,842
Ensembl chr 1:189,665,976...189,685,842
JBrowse link
G Lyz2 lysozyme 2 decreases expression ISO Fenofibrate results in decreased expression of LYZ2 mRNA CTD PMID:11798191 NCBI chr 7:60,335,968...60,341,264
Ensembl chr 7:60,335,969...60,341,264
JBrowse link
G Mafg MAF bZIP transcription factor G decreases expression
increases expression
EXP
ISO
Fenofibrate results in decreased expression of MAFG mRNA
Fenofibrate results in increased expression of MAFG mRNA
CTD PMID:25596134 NCBI chr10:109,802,877...109,811,476
Ensembl chr10:109,806,159...109,811,323
JBrowse link
G Man1a1 mannosidase, alpha, class 1A, member 1 decreases expression EXP Fenofibrate results in decreased expression of MAN1A mRNA CTD PMID:16707586 NCBI chr20:35,257,688...35,450,132
Ensembl chr20:35,257,985...35,450,513
JBrowse link
G Man1a2 mannosidase, alpha, class 1A, member 2 decreases expression EXP Fenofibrate results in decreased expression of MAN1A2 mRNA CTD PMID:25596134 NCBI chr 2:202,891,537...203,043,847
Ensembl chr 2:202,891,537...203,043,847
JBrowse link
G Maob monoamine oxidase B multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of MAOB mRNA CTD PMID:18253720 NCBI chr  X:6,430,694...6,533,520
Ensembl chr  X:6,430,594...6,533,534
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha increases expression
multiple interactions
ISO Fenofibrate results in increased expression of MAP1LC3A mRNA
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of MAP1LC3A mRNA
CTD PMID:21318169 NCBI chr 3:150,801,289...150,802,935
Ensembl chr 3:150,801,289...150,802,935
JBrowse link
G Mat2a methionine adenosyltransferase 2A decreases expression ISO Fenofibrate results in decreased expression of MAT2A mRNA CTD PMID:16569247 NCBI chr 4:100,297,478...100,303,047
Ensembl chr 4:100,296,075...100,303,080
JBrowse link
G Mc1r melanocortin 1 receptor decreases expression
multiple interactions
ISO Fenofibrate results in decreased expression of MC1R mRNA
[Fenofibrate results in decreased expression of MC1R mRNA] which results in decreased chemical synthesis of Melanins
CTD PMID:23872139 NCBI chr19:56,215,420...56,219,987 JBrowse link
G Mdh2 malate dehydrogenase 2 increases expression ISO Fenofibrate results in increased expression of MDH mRNA CTD PMID:24752549 NCBI chr12:23,941,451...23,954,406
Ensembl chr12:23,941,448...23,954,431
JBrowse link
G Mdm2 MDM2 proto-oncogene decreases expression EXP Fenofibrate results in decreased expression of MDM2 mRNA CTD PMID:25596134 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Me1 malic enzyme 1 affects expression
increases expression
multiple interactions
EXP
ISO
Fenofibrate affects the expression of ME1 mRNA
Fenofibrate results in increased expression of ME1 mRNA
NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA]
CTD PMID:20801182, PMID:23063693, PMID:25596134, PMID:27071702 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Mertk MER proto-oncogene, tyrosine kinase increases expression ISO Fenofibrate results in increased expression of MERTK mRNA CTD PMID:25572481 NCBI chr 3:121,235,230...121,340,932
Ensembl chr 3:121,235,119...121,342,444
JBrowse link
G Mfsd2a major facilitator superfamily domain containing 2A decreases expression ISO Fenofibrate results in decreased expression of MFSD2A mRNA CTD PMID:25572481 NCBI chr 5:140,642,865...140,657,759
Ensembl chr 5:140,642,885...140,657,745
JBrowse link
G Mgll monoglyceride lipase increases expression ISO
EXP
Fenofibrate results in increased expression of MGLL mRNA CTD PMID:11798191, PMID:17118139, PMID:27665778 NCBI chr 4:120,671,436...120,773,458
Ensembl chr 4:120,671,489...120,771,088
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase multiple interactions
increases expression
EXP [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of MGMT mRNA
Fenofibrate results in increased expression of MGMT mRNA
CTD PMID:17264098, PMID:18253720 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Mgrn1 mahogunin ring finger 1 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of MGRN1 mRNA
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of MGRN1 mRNA
CTD PMID:21318169 NCBI chr10:10,832,573...10,881,999
Ensembl chr10:10,833,519...10,881,977
JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 increases expression ISO Fenofibrate results in increased expression of MGST3 mRNA CTD PMID:11798191 NCBI chr13:85,601,499...85,622,392
Ensembl chr13:85,601,499...85,622,314
JBrowse link
G Mitf melanocyte inducing transcription factor decreases expression ISO Fenofibrate results in decreased expression of MITF mRNA; Fenofibrate results in decreased expression of MITF protein CTD PMID:23872139 NCBI chr 4:130,172,484...130,425,496
Ensembl chr 4:130,172,727...130,425,532
JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression EXP Fenofibrate results in increased expression of MKI67 protein CTD PMID:17264098 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mlh1 mutL homolog 1 multiple interactions
increases expression
EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of MLH1 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of MLH1 mRNA
Fenofibrate results in increased expression of MLH1 mRNA
CTD PMID:17264098, PMID:18253720, PMID:18775883 NCBI chr 8:119,486,655...119,523,716
Ensembl chr 8:119,486,691...119,523,964
JBrowse link
G Mlycd malonyl-CoA decarboxylase multiple interactions EXP [Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in decreased expression of MLYCD mRNA]; Fenofibrate inhibits the reaction [Fructose results in decreased expression of MLYCD mRNA]; Fenofibrate promotes the reaction [PPARA protein results in increased expression of MLYCD mRNA] CTD PMID:14641110, PMID:26973390 NCBI chr19:52,032,950...52,048,773
Ensembl chr19:52,032,886...52,048,753
JBrowse link
G Mmd monocyte to macrophage differentiation-associated increases expression ISO Fenofibrate results in increased expression of MMD mRNA CTD PMID:25572481 NCBI chr10:77,687,964...77,783,737
Ensembl chr10:77,755,216...77,783,779
JBrowse link
G Mmp1 matrix metallopeptidase 1 decreases expression ISO Fenofibrate results in decreased expression of MMP1 protein CTD PMID:25545733 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp19 matrix metallopeptidase 19 increases expression EXP Fenofibrate results in increased expression of MMP19 mRNA CTD PMID:25596134 NCBI chr 7:3,216,392...3,224,202
Ensembl chr 7:3,216,497...3,224,201
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO Fenofibrate results in decreased expression of MMP2 protein CTD PMID:25545733 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp7 matrix metallopeptidase 7 decreases expression ISO Fenofibrate results in decreased expression of MMP7 protein CTD PMID:25545733 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
ISO Fenofibrate inhibits the reaction [Dinoprostone results in increased expression of MMP9 mRNA]; Fenofibrate inhibits the reaction [Dinoprostone results in increased secretion of MMP9 protein]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP9 protein]
Fenofibrate results in decreased expression of MMP9 protein
CTD PMID:19880272, PMID:21075133, PMID:25545733 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mrap melanocortin 2 receptor accessory protein increases expression ISO Fenofibrate results in increased expression of MRAP mRNA CTD PMID:11798191 NCBI chr11:30,904,733...30,915,225
Ensembl chr11:30,904,733...30,915,225
JBrowse link
G Ms4a10 membrane spanning 4-domains A10 decreases expression ISO Fenofibrate results in decreased expression of MS4A10 mRNA CTD PMID:25572481 NCBI chr 1:227,016,795...227,030,220
Ensembl chr 1:227,016,803...227,029,943
JBrowse link
G Msc musculin decreases expression EXP Fenofibrate results in decreased expression of MSC mRNA CTD PMID:25596134 NCBI chr 5:3,954,902...3,956,974
Ensembl chr 5:3,955,227...3,956,572
JBrowse link
G Msmo1 methylsterol monooxygenase 1 affects expression EXP Fenofibrate affects the expression of MSMO1 mRNA CTD PMID:20801182 NCBI chr16:26,859,441...26,875,880
Ensembl chr16:26,859,397...26,875,973
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of MYC mRNA CTD PMID:18978307 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Mylk myosin light chain kinase decreases expression ISO Fenofibrate results in decreased expression of MYLK mRNA CTD PMID:25572481 NCBI chr11:69,013,060...69,260,039
Ensembl chr11:69,013,050...69,223,158
JBrowse link
G N4bp2l1 NEDD4 binding protein 2-like 1 increases expression ISO Fenofibrate results in increased expression of N4BP2L1 mRNA CTD PMID:25572481 NCBI chr12:546,759...576,744
Ensembl chr12:546,760...576,746
JBrowse link
G Nacc1 nucleus accumbens associated 1 increases expression EXP Fenofibrate results in increased expression of NACC1 mRNA CTD PMID:17264098 NCBI chr19:25,783,686...25,801,526
Ensembl chr19:25,783,900...25,801,526
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression EXP Fenofibrate results in increased expression of NAMPT mRNA CTD PMID:25596134 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Nars1 asparaginyl-tRNA synthetase 1 affects expression EXP Fenofibrate affects the expression of NARS1 mRNA CTD PMID:25596134 NCBI chr18:59,986,350...60,002,644
Ensembl chr18:59,986,360...60,002,569
JBrowse link
G Nat8f3 N-acetyltransferase 8 (GCN5-related) family member 3 multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of NAT8F3 mRNA CTD PMID:18253720 NCBI chr 4:117,488,089...117,492,315
Ensembl chr 4:117,490,035...117,490,721
JBrowse link
G Nbn nibrin multiple interactions
increases expression
EXP [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of NBN mRNA
Fenofibrate results in increased expression of NBN mRNA
CTD PMID:17264098, PMID:18253720, PMID:18775883 NCBI chr 5:29,622,347...29,656,877
Ensembl chr 5:29,622,281...29,656,864
JBrowse link
G Nceh1 neutral cholesterol ester hydrolase 1 increases expression EXP Fenofibrate results in increased expression of NCEH1 mRNA CTD PMID:27665778 NCBI chr 2:112,868,834...112,932,622
Ensembl chr 2:112,868,707...112,934,953
JBrowse link
G Ndufab1 NADH:ubiquinone oxidoreductase subunit AB1 increases expression ISO Fenofibrate results in increased expression of NDUFAB1 mRNA CTD PMID:11798191 NCBI chr 1:192,044,209...192,057,644
Ensembl chr 1:192,044,216...192,057,612
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase increases expression
multiple interactions
ISO Fenofibrate results in increased expression of NEDD4 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of NEDD4 mRNA]
CTD PMID:21318169 NCBI chr 8:79,323,408...79,408,842
Ensembl chr 8:79,323,408...79,408,833
JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 decreases expression ISO
EXP
Fenofibrate results in decreased expression of NEDD9 mRNA CTD PMID:25596134 NCBI chr17:22,984,792...23,179,701
Ensembl chr17:22,984,844...23,179,701
JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 multiple interactions EXP EDN1 protein promotes the reaction [Fenofibrate promotes the reaction [NFATC4 protein binds to PPARA protein]]; Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]; Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to NPPB promoter]]; Fenofibrate promotes the reaction [NFATC4 protein binds to PPARA protein]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]] CTD PMID:22198280 NCBI chr15:34,493,163...34,502,238
Ensembl chr15:34,493,138...34,504,326
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
increases activity
decreases expression
affects activity
EXP
ISO
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of NFE2L2 protein
Fenofibrate inhibits the reaction [triptolide results in increased expression of NFE2L2 mRNA]; Fenofibrate inhibits the reaction [triptolide results in increased expression of NFE2L2 protein]
Fenofibrate results in increased activity of NFE2L2 protein
Fenofibrate results in decreased expression of NFE2L2 mRNA
Fenofibrate affects the activity of NFE2L2 protein
CTD PMID:18775883, PMID:25596134, PMID:30114225, PMID:30203046, PMID:31241159 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
affects localization
ISO Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of NFKB1 protein]
Fenofibrate affects the localization of NFKB1 protein
CTD PMID:20580385, PMID:25545733 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
decreases expression
ISO Fenofibrate inhibits the reaction [ALB protein modified form results in increased degradation of NFKBIA protein]
Fenofibrate results in decreased expression of NFKBIA protein modified form
CTD PMID:20580385, PMID:25545733 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nfkbib NFKB inhibitor beta multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of NFKBIB mRNA; [Fenofibrate co-treated with Sodium Glutamate] results in increased expression of NFKBIB mRNA CTD PMID:18253720, PMID:21999347 NCBI chr 1:86,941,073...86,948,845
Ensembl chr 1:86,941,074...86,948,845
JBrowse link
G Ninj1 ninjurin 1 affects expression EXP Fenofibrate affects the expression of NINJ1 mRNA CTD PMID:25596134 NCBI chr17:15,866,235...15,881,284
Ensembl chr17:15,866,237...15,881,327
JBrowse link
G Nmur1 neuromedin U receptor 1 decreases expression EXP Fenofibrate results in decreased expression of NMUR1 mRNA CTD PMID:25596134 NCBI chr 9:93,402,871...93,407,264
Ensembl chr 9:93,403,314...93,404,883
JBrowse link
G Nnmt nicotinamide N-methyltransferase multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of NNMT mRNA CTD PMID:18253720 NCBI chr 8:52,918,437...52,938,172
Ensembl chr 8:52,925,175...52,937,972
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO
EXP
Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]
[Fenofibrate co-treated with Sodium Glutamate] results in increased expression of NOS2 mRNA; [Fenofibrate co-treated with Sodium Glutamate] results in increased expression of NOS2 protein
CTD PMID:21300114, PMID:21999347 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
increases phosphorylation
increases activity
ISO dorsomorphin inhibits the reaction [Fenofibrate results in increased activity of NOS3 protein]; Fenofibrate inhibits the reaction [Wortmannin results in decreased phosphorylation of NOS3 protein]; PRKAA1 protein affects the reaction [Fenofibrate results in increased activity of NOS3 protein]
Fenofibrate results in increased phosphorylation of NOS3 protein
CTD PMID:16442496, PMID:20580385 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Notch1 notch receptor 1 multiple interactions ISO Fenofibrate inhibits the reaction [triptolide results in increased expression of NOTCH1 mRNA] CTD PMID:31241159 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Notch3 notch receptor 3 multiple interactions ISO Fenofibrate inhibits the reaction [triptolide results in increased expression of NOTCH3 mRNA]; Fenofibrate inhibits the reaction [triptolide results in increased expression of NOTCH3 protein] CTD PMID:31241159 NCBI chr 7:14,138,495...14,189,688
Ensembl chr 7:14,138,495...14,189,688
JBrowse link
G Nppa natriuretic peptide A multiple interactions ISO Fenofibrate inhibits the reaction [Doxorubicin results in decreased expression of NPPA mRNA] CTD PMID:17531194 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Nppb natriuretic peptide B multiple interactions EXP Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to NPPB promoter]]; Fenofibrate inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]] CTD PMID:22198280 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 multiple interactions
increases expression
ISO
EXP
Dactinomycin inhibits the reaction [Fenofibrate results in increased expression of NR0B2 mRNA]; dorsomorphin inhibits the reaction [Fenofibrate results in increased expression of NR0B2 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD4 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]]; pyrazolanthrone inhibits the reaction [Fenofibrate results in increased expression of NR0B2 mRNA]
[Methionine deficiency co-treated with Choline deficiency co-treated with Fenofibrate] results in increased expression of NR0B2 mRNA; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of IL6 mRNA]]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 mRNA]]; NR0B2 protein promotes the reaction [[Methionine deficiency co-treated with Choline deficiency co-treated with Fenofibrate] results in increased expression of CYP4A14 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of FAS mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SREBF1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TGFB1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF mRNA]]
Fenofibrate results in increased expression of NR0B2 mRNA; Fenofibrate results in increased expression of NR0B2 protein
CTD PMID:19593819 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of NR1H2 mRNA
NR1H2 gene mutant form affects the reaction [Fenofibrate results in increased expression of ACACB mRNA]; NR1H2 gene mutant form affects the reaction [Fenofibrate results in increased expression of SCD1 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A10 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A14 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FDFT1 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of HMGCR mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LSS mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of PPARA mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SQLE mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SREBF1 mRNA]
CTD PMID:19201410, PMID:23063693 NCBI chr 1:100,554,577...100,559,896
Ensembl chr 1:100,554,544...100,559,942
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 increases expression
multiple interactions
affects response to substance
ISO Fenofibrate results in increased expression of NR1H3 mRNA
NR1H3 gene mutant form affects the reaction [Fenofibrate results in increased expression of ACACB mRNA]; NR1H3 gene mutant form affects the reaction [Fenofibrate results in increased expression of SCD1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A10 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A14 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FDFT1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of HMGCR mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LSS mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of PPARA mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SQLE mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SREBF1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of NR1H3 mRNA]
NR1H3 protein affects the susceptibility to Fenofibrate
[Oleic Acid co-treated with Fenofibrate] affects the expression of NR1H3 mRNA; NR1H3 protein affects the reaction [Fenofibrate results in increased expression of PPARA mRNA]
CTD PMID:19201410, PMID:23063693, PMID:24534255, PMID:25949234 NCBI chr 3:80,004,130...80,014,197
Ensembl chr 3:80,004,130...80,012,750
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions
increases expression
ISO
EXP
[Oleic Acid co-treated with Fenofibrate] results in decreased expression of NR1H4 mRNA
fenofibrate increases expression of Nr1h4 mRNA in steatotic liver
CTD PMID:24534255, PMID:30257410 RGD:15090799 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO Fenofibrate binds to and results in increased activity of NR1I2 protein CTD PMID:20024649 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 affects localization
increases activity
multiple interactions
increases expression
ISO
EXP
Fenofibrate affects the localization of NR1I3 protein
Fenofibrate results in increased activity of NR1I3 protein
[Oleic Acid co-treated with Fenofibrate] results in increased expression of NR1I3 mRNA; Fenofibrate binds to and results in increased activity of NR1I3 protein alternative form
Fenofibrate results in increased expression of NR1I3 mRNA
CTD PMID:17962186, PMID:19118567, PMID:24534255, PMID:30203046, PMID:31312845 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions ISO Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]] CTD PMID:19593819 NCBI chr 7:142,899,358...142,920,216
Ensembl chr 7:142,905,758...142,920,216
JBrowse link
G Nrep neuronal regeneration related protein decreases expression ISO Fenofibrate results in decreased expression of NREP mRNA CTD PMID:25596134 NCBI chr18:26,183,753...26,212,796
Ensembl chr18:26,185,259...26,211,445
JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like increases expression ISO Fenofibrate results in increased expression of NSDHL mRNA CTD PMID:11798191 NCBI chr  X:152,933,118...152,964,399
Ensembl chr  X:152,933,069...152,964,390
JBrowse link
G Ntpcr nucleoside-triphosphatase, cancer-related affects expression EXP Fenofibrate affects the expression of NTPCR mRNA CTD PMID:25596134 NCBI chr19:58,565,576...58,579,276
Ensembl chr19:58,565,576...58,579,265
JBrowse link
G Nuak1 NUAK family kinase 1 decreases expression ISO Fenofibrate results in decreased expression of NUAK1 mRNA CTD PMID:25596134 NCBI chr 7:25,039,336...25,111,118
Ensembl chr 7:25,039,335...25,113,664
JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like increases expression ISO Fenofibrate results in increased expression of OASL mRNA CTD PMID:25572481 NCBI chr12:47,444,138...47,456,680
Ensembl chr12:47,444,104...47,456,894
JBrowse link
G Orai3 ORAI calcium release-activated calcium modulator 3 decreases expression ISO Fenofibrate results in decreased expression of ORAI3 mRNA CTD PMID:25596134 NCBI chr 1:199,217,504...199,222,363
Ensembl chr 1:199,217,016...199,222,851
JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 decreases expression EXP Fenofibrate results in decreased expression of OSGIN1 mRNA CTD PMID:25596134 NCBI chr19:52,056,808...52,085,491
Ensembl chr19:52,077,109...52,085,496
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 affects expression EXP Fenofibrate affects the expression of P4HA1 mRNA CTD PMID:25596134 NCBI chr20:28,920,616...28,972,576
Ensembl chr20:28,920,616...28,971,966
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta affects expression EXP Fenofibrate affects the expression of P4HB mRNA CTD PMID:20801182 NCBI chr10:109,736,459...109,748,070
Ensembl chr10:109,736,458...109,747,987
JBrowse link
G Pank1 pantothenate kinase 1 increases expression EXP
ISO
Fenofibrate results in increased expression of PANK1 mRNA CTD PMID:16707586, PMID:25572481, PMID:25596134 NCBI chr 1:253,115,400...253,189,643
Ensembl chr 1:253,119,112...253,185,533
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 increases expression ISO Fenofibrate results in increased expression of PCK1 mRNA CTD PMID:25572481 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) increases expression ISO Fenofibrate results in increased expression of PCK2 mRNA CTD PMID:16569247, PMID:24752549 NCBI chr15:34,216,735...34,224,357
Ensembl chr15:34,216,833...34,224,193
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions
increases expression
ISO [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of PCNA protein
ESR1 protein inhibits the reaction [Fenofibrate results in increased expression of PCNA protein]; Estradiol inhibits the reaction [Fenofibrate results in increased expression of PCNA protein]
CTD PMID:18978307, PMID:29134746 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 increases expression ISO Fenofibrate results in increased expression of PCSK9 protein CTD PMID:21411093 NCBI chr 5:126,031,368...126,053,726
Ensembl chr 5:126,031,368...126,053,726
JBrowse link
G Pdia5 protein disulfide isomerase family A, member 5 decreases expression EXP Fenofibrate results in decreased expression of PDIA5 mRNA CTD PMID:25596134 NCBI chr11:68,493,035...68,578,999
Ensembl chr11:68,493,035...68,578,995
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 decreases expression EXP Fenofibrate results in decreased expression of PDK1 mRNA CTD PMID:25596134 NCBI chr 3:58,530,870...58,561,494
Ensembl chr 3:58,530,870...58,558,027
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO
EXP
Fenofibrate results in increased expression of PDK4 mRNA CTD PMID:17118139, PMID:19395589, PMID:25572481, PMID:25596134, PMID:27665778 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Pdlim1 PDZ and LIM domain 1 decreases expression EXP Fenofibrate results in decreased expression of PDLIM1 mRNA CTD PMID:25596134 NCBI chr 1:259,308,326...259,357,006
Ensembl chr 1:259,308,296...259,357,056
JBrowse link
G Pdrg1 p53 and DNA damage regulated 1 multiple interactions
decreases expression
ISO PPARA protein affects the reaction [Fenofibrate results in decreased expression of PDRG1 mRNA] CTD PMID:21318169 NCBI chr 3:148,487,056...148,493,225
Ensembl chr 3:148,487,059...148,493,225
JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase increases expression ISO Fenofibrate results in increased expression of PEMT mRNA CTD PMID:25572481 NCBI chr10:46,339,821...46,404,640
Ensembl chr10:46,339,821...46,404,642
JBrowse link
G Pex11a peroxisomal biogenesis factor 11 alpha affects expression
increases expression
EXP
ISO
Fenofibrate affects the expression of PEX11A mRNA
Fenofibrate results in increased expression of PEX11A mRNA
CTD PMID:20801182, PMID:25572481, PMID:27665778 NCBI chr 1:141,474,189...141,481,270
Ensembl chr 1:141,474,180...141,481,315
JBrowse link
G Pgm1 phosphoglucomutase 1 increases expression ISO Fenofibrate results in increased expression of PGM1 mRNA CTD PMID:24752549 NCBI chr 5:118,743,632...118,803,055
Ensembl chr 5:118,743,632...118,803,055
JBrowse link
G Phgdh phosphoglycerate dehydrogenase increases expression EXP
ISO
Fenofibrate results in increased expression of PHGDH mRNA CTD PMID:25596134 NCBI chr 2:200,484,245...200,513,564
Ensembl chr 2:200,484,246...200,513,564
JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 decreases expression ISO Fenofibrate results in decreased expression of PHLDA1 mRNA CTD PMID:11798191 NCBI chr 7:54,247,460...54,249,664
Ensembl chr 7:54,247,460...54,249,664
JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 affects expression EXP Fenofibrate affects the expression of PHLDA3 mRNA CTD PMID:25596134 NCBI chr13:52,588,917...52,592,002
Ensembl chr13:52,588,917...52,592,001
JBrowse link
G Pik3c2g phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma decreases expression EXP Fenofibrate results in decreased expression of PIK3C2G mRNA CTD PMID:16707586 NCBI chr 4:173,732,196...174,102,502
Ensembl chr 4:173,732,248...174,102,496
JBrowse link
G Pir pirin decreases expression EXP Fenofibrate results in decreased expression of PIR mRNA CTD PMID:25596134 NCBI chr  X:31,852,322...31,968,152
Ensembl chr  X:31,852,323...31,968,152
JBrowse link
G Pja2 praja ring finger ubiquitin ligase 2 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of PJA2 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of PJA2 mRNA]
CTD PMID:21318169 NCBI chr 9:111,998,204...112,048,847
Ensembl chr 9:111,998,203...112,027,240
JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta increases expression ISO Fenofibrate results in increased expression of PKIB mRNA CTD PMID:25572481 NCBI chr20:40,616,868...40,712,598
Ensembl chr20:40,618,128...40,712,592
JBrowse link
G Pklr pyruvate kinase L/R decreases expression ISO Fenofibrate results in decreased expression of PKLR mRNA CTD PMID:25572481 NCBI chr 2:188,449,158...188,458,034
Ensembl chr 2:188,449,210...188,459,592
JBrowse link
G Pla1a phospholipase A1 member A increases expression ISO Fenofibrate results in increased expression of PLA1A mRNA CTD PMID:25572481 NCBI chr11:64,882,024...64,919,714
Ensembl chr11:64,882,288...64,919,579
JBrowse link
G Pla2g7 phospholipase A2 group VII decreases activity
multiple interactions
ISO Fenofibrate results in decreased activity of PLA2G7 protein
[orlistat co-treated with Fenofibrate] results in decreased activity of PLA2G7 protein
CTD PMID:16911813 NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013
JBrowse link
G Plcxd3 phosphatidylinositol-specific phospholipase C, X domain containing 3 decreases expression ISO Fenofibrate results in decreased expression of PLCXD3 mRNA CTD PMID:25572481 NCBI chr 2:54,191,538...54,360,780
Ensembl chr 2:54,191,538...54,360,780
JBrowse link
G Plin1 perilipin 1 increases expression ISO Fenofibrate results in increased expression of PLIN1 mRNA CTD PMID:25572481 NCBI chr 1:141,458,907...141,470,927
Ensembl chr 1:141,458,181...141,471,010
JBrowse link
G Plin2 perilipin 2 increases expression
multiple interactions
ISO
EXP
Fenofibrate results in increased expression of PLIN2 mRNA
Fenofibrate promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA]
CTD PMID:24534255, PMID:25572481, PMID:25596134, PMID:27665778 NCBI chr 5:104,984,413...105,010,863
Ensembl chr 5:104,984,414...105,010,857
JBrowse link
G Plin4 perilipin 4 increases expression ISO Fenofibrate results in increased expression of PLIN4 mRNA CTD PMID:25572481 NCBI chr 9:10,963,494...10,972,360
Ensembl chr 9:10,963,723...10,971,277
JBrowse link
G Pltp phospholipid transfer protein increases expression ISO Fenofibrate results in increased expression of PLTP mRNA CTD PMID:11798191 NCBI chr 3:161,304,469...161,322,289
Ensembl chr 3:161,304,469...161,322,289
JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 decreases expression EXP Fenofibrate results in decreased expression of PMEPA1 mRNA CTD PMID:25596134 NCBI chr 3:171,295,630...171,342,662
Ensembl chr 3:171,294,856...171,342,646
JBrowse link
G Podxl podocalyxin-like decreases expression ISO
EXP
Fenofibrate results in decreased expression of PODXL mRNA CTD PMID:25596134 NCBI chr 4:58,829,049...58,893,353
Ensembl chr 4:58,829,060...58,893,170
JBrowse link
G Pon1 paraoxonase 1 increases expression ISO Fenofibrate results in increased expression of PON1 protein CTD PMID:16123850 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression EXP
ISO
Fenofibrate results in increased expression of POR mRNA CTD PMID:16707586, PMID:25572481 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Ppan peter pan homolog affects expression EXP Fenofibrate affects the expression of PPAN mRNA CTD PMID:25596134 NCBI chr 8:21,905,865...21,909,845
Ensembl chr 8:21,905,865...21,909,842
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression
increases response to substance
increases activity
decreases response to substance
multiple interactions
increases expression
affects response to substance
ISO
EXP
Fenofibrate results in decreased expression of PPARA mRNA
PPARA protein results in increased susceptibility to Fenofibrate
Fenofibrate results in increased activity of PPARA protein
PPARA gene mutant form results in decreased susceptibility to Fenofibrate
[Fenofibrate co-treated with Fatty Acids, Nonesterified] results in increased expression of PPARA mRNA; ESR1 protein inhibits the reaction [Estradiol inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]]; ESR1 protein inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]; Estradiol inhibits the reaction [ESR1 protein inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]]; Estradiol inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]; Fenofibrate binds to and results in increased activity of PPARA protein; Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of PPARA mRNA]; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of PPARA protein]; NR1H3 protein affects the reaction [Fenofibrate results in increased expression of PPARA mRNA]; PPARA protein inhibits the reaction [Fenofibrate results in decreased expression of APOA1 mRNA]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of ACOX1 protein]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of ACSL1 protein]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of LPL protein]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of SLC27A4 protein]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of UCP2 protein]
[Fenofibrate binds to and results in increased activity of PPARA protein] which affects the abundance of Fatty Acids, Nonesterified; [Fenofibrate binds to and results in increased activity of PPARA protein] which affects the abundance of Triglycerides; [Fenofibrate results in increased activity of PPARA protein] which results in decreased abundance of Adenosine Triphosphate; [Fenofibrate results in increased activity of PPARA protein] which results in increased expression of TRIB3 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of ASB6 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of BRCC3 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC14 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC19 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC2 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of FKBP15 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of HECTD1 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of HSPB8 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of MAP1LC3A mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of MGRN1 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of PRKAB2 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of SEC63 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of SMPD3 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of TOPORS mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of UBR2 mRNA; Fenofibrate binds to and results in increased activity of PPARA protein; Fenofibrate inhibits the reaction [Zoledronic Acid results in decreased expression of PPARA mRNA]; Fenofibrate promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Fenofibrate results in increased expression of and results in increased activity of PPARA protein; Lipopolysaccharides inhibits the reaction [Fenofibrate results in increased expression of PPARA mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of PPARA mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of PPARA mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACB mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACLY mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 protein]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACSL1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACSL1 protein]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A10 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A14 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LPL mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LPL protein]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of NR1H3 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SLC27A4 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SLC27A4 protein]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of UCP2 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of UCP2 protein]; PPARA promotes the reaction [Fenofibrate results in decreased expression of FGA mRNA]; PPARA protein affects the reaction [Fenofibrate affects the expression of BRAP mRNA]; PPARA protein affects the reaction [Fenofibrate promotes the reaction [APOA1 protein results in increased secretion of Lipids]]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of ANAPC11 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of CISH mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of CYLD mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of DNAJB4 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of ITCH mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of LNX1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of LRSAM1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of PDRG1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of PPP3CA mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of PRKAB1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of RBJ mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of RNF144B mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of STCH mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of UBE2R2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of URM1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of USP36 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of WSB1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ARIH1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ATE1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ATG12 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ATG7 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of CANX mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of CBLB mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of CNOT4 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJA2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJB6 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJC3 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJC5 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ENC1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO3 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO30 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of GRPEL2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSP90AA1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSP90AB1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA4L mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA8 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA9 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPB1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPH1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of NEDD4 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of PJA2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of PPP1R15B mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMB2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMC6 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMD4 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of RABGEF1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of RNF14 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of SENP2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of SOCS6 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of SPOP mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of TOR1B mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of TOR3A mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of TRIP12 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of UBE2Q2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of UBE3A mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of URI1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP10 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP22 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP38 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP7 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP9X mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USPL1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of VCPIP1 mRNA]
Fenofibrate results in increased expression of PPARA mRNA; Fenofibrate results in increased expression of PPARA protein
PPARA protein results in increased susceptibility to Fenofibrate; PPARA results in increased susceptibility to Fenofibrate
[Fenofibrate binds to and results in increased activity of PPARA protein] which results in increased expression of UCP2 mRNA; EDN1 protein promotes the reaction [Fenofibrate promotes the reaction [NFATC4 protein binds to PPARA protein]]; Fenofibrate binds to and results in increased activity of PPARA protein; Fenofibrate inhibits the reaction [Fructose results in decreased expression of and results in decreased activity of PPARA protein]; Fenofibrate inhibits the reaction [Pyrazinamide results in decreased expression of PPARA mRNA]; Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of PPARA mRNA]; Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of PPARA protein]; Fenofibrate promotes the reaction [NFATC4 protein binds to PPARA protein]; Fenofibrate promotes the reaction [PPARA protein results in increased expression of MLYCD mRNA]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]]
CTD PMID:7983038, PMID:10216095, PMID:11341955, PMID:11798191, PMID:11934685, PMID:12759900, PMID:14641110, PMID:15299082, PMID:15968640, PMID:16569247, PMID:17201732, PMID:17655842, PMID:18300857, PMID:18356826, PMID:18812576, PMID:19118567, PMID:19124612, PMID:19201410, PMID:19445040, PMID:19569716, PMID:19593819, PMID:20520642, PMID:21300114, PMID:21318169, PMID:22198280, PMID:23063693, PMID:24735863, PMID:24752549, PMID:24986865, PMID:25035112, PMID:25689681, PMID:25949234, PMID:26989860, PMID:27071702, PMID:28743512, PMID:28871336, PMID:29134746, PMID:30203046 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta increases expression ISO Fenofibrate results in increased expression of PPARD mRNA CTD PMID:19201410 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression
affects activity
multiple interactions
ISO
EXP
Fenofibrate results in increased expression of PPARG mRNA
Fenofibrate affects the activity of PPARG protein
[Oleic Acid co-treated with Fenofibrate] results in increased expression of PPARG mRNA
CTD PMID:19201410, PMID:24534255, PMID:25596134, PMID:28034800 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of PPARGC1A mRNA] CTD PMID:28871336 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Ppcs phosphopantothenoylcysteine synthetase increases expression EXP Fenofibrate results in increased expression of PPCS mRNA CTD PMID:27665778 NCBI chr 5:138,466,298...138,470,108
Ensembl chr 5:138,466,293...138,470,096
JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D decreases expression EXP Fenofibrate results in decreased expression of PPM1D mRNA CTD PMID:25596134 NCBI chr10:72,909,550...72,945,884
Ensembl chr10:72,909,550...72,945,884
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression
decreases expression
ISO
EXP
Fenofibrate results in increased expression of PPP1R15A mRNA
Fenofibrate results in decreased expression of PPP1R15A mRNA
CTD PMID:25596134 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Ppp1r15b protein phosphatase 1, regulatory subunit 15B increases expression
multiple interactions
ISO Fenofibrate results in increased expression of PPP1R15B mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of PPP1R15B mRNA]
CTD PMID:21318169 NCBI chr13:49,933,155...49,940,961
Ensembl chr13:49,933,155...49,940,961
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha multiple interactions
decreases expression
ISO PPARA protein affects the reaction [Fenofibrate results in decreased expression of PPP3CA mRNA] CTD PMID:21318169 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions
decreases response to substance
ISO PRKAA1 protein affects the reaction [Fenofibrate results in decreased susceptibility to ALB protein modified form]; PRKAA1 protein affects the reaction [Fenofibrate results in increased abundance of Nitric Oxide]; PRKAA1 protein affects the reaction [Fenofibrate results in increased activity of NOS3 protein]
PRKAA1 gene mutant form results in decreased susceptibility to Fenofibrate
CTD PMID:20580385, PMID:25545733 NCBI chr 2:54,857,688...54,893,404
Ensembl chr 2:54,857,688...54,893,404
JBrowse link
G Prkab1 protein kinase AMP-activated non-catalytic subunit beta 1 decreases expression
increases phosphorylation
multiple interactions
ISO Fenofibrate results in decreased expression of PRKAB1 mRNA
Fenofibrate results in increased phosphorylation of PRKAB1 protein
PPARA protein affects the reaction [Fenofibrate results in decreased expression of PRKAB1 mRNA]
CTD PMID:21318169, PMID:25545733 NCBI chr12:46,316,298...46,326,789
Ensembl chr12:46,316,236...46,326,790
JBrowse link
G Prkab2 protein kinase AMP-activated non-catalytic subunit beta 2 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of PRKAB2 mRNA
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of PRKAB2 mRNA
CTD PMID:21318169 NCBI chr 2:199,831,990...199,847,623
Ensembl chr 2:199,831,990...199,847,629
JBrowse link
G Prkag1 protein kinase AMP-activated non-catalytic subunit gamma 1 increases expression ISO Fenofibrate results in increased expression of PRKAG1 protein CTD PMID:25545733 NCBI chr 7:140,489,499...140,506,925
Ensembl chr 7:140,489,492...140,546,908
JBrowse link
G Prodh1 proline dehydrogenase 1 decreases expression ISO Fenofibrate results in decreased expression of PRODH mRNA CTD PMID:25572481 NCBI chr11:87,058,478...87,075,785
Ensembl chr11:87,058,616...87,075,785
JBrowse link
G Psen1 presenilin 1 multiple interactions ISO Fenofibrate affects the reaction [PSEN1 protein affects the cleavage of APP protein] CTD PMID:17962197 NCBI chr 6:107,169,514...107,221,000
Ensembl chr 6:107,169,528...107,216,798
JBrowse link
G Psmb2 proteasome 20S subunit beta 2 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of PSMB2 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMB2 mRNA]
CTD PMID:21318169 NCBI chr 5:144,702,004...144,734,220
Ensembl chr 5:144,701,949...144,734,257
JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of PSMC6 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMC6 mRNA]
CTD PMID:21318169 NCBI chr15:19,667,453...19,688,916
Ensembl chr15:19,667,453...19,688,914
JBrowse link
G Psmd4 proteasome 26S subunit, non-ATPase 4 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of PSMD4 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMD4 mRNA]
CTD PMID:21318169 NCBI chr 2:196,198,303...196,207,569
Ensembl chr 2:196,198,038...196,207,560
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of PTGS1 mRNA CTD PMID:18253720 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:21300114 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptprf protein tyrosine phosphatase, receptor type, F affects expression EXP Fenofibrate affects the expression of PTPRF mRNA CTD PMID:20801182 NCBI chr 5:137,036,936...137,112,930
Ensembl chr 5:137,036,935...137,112,927
JBrowse link
G Ptprq protein tyrosine phosphatase, receptor type, Q decreases expression ISO Fenofibrate results in decreased expression of PTPRQ mRNA CTD PMID:25572481 NCBI chr 7:49,763,657...50,034,932
Ensembl chr 7:49,763,657...50,034,932
JBrowse link
G Pygl glycogen phosphorylase L increases expression EXP Fenofibrate results in increased expression of PYGL mRNA CTD PMID:25596134 NCBI chr 6:92,597,759...92,643,734
Ensembl chr 6:92,597,706...92,643,847
JBrowse link
G Qpct glutaminyl-peptide cyclotransferase increases expression EXP Fenofibrate results in increased expression of QPCT mRNA CTD PMID:27665778 NCBI chr 6:1,657,110...1,689,575
Ensembl chr 6:1,657,331...1,689,559
JBrowse link
G Rab31 RAB31, member RAS oncogene family decreases expression ISO Fenofibrate results in decreased expression of RAB31 mRNA CTD PMID:25596134 NCBI chr 9:113,370,072...113,504,606
Ensembl chr 9:113,370,033...113,504,605
JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of RABGEF1 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of RABGEF1 mRNA]
CTD PMID:21318169 NCBI chr12:29,960,132...30,004,727
Ensembl chr12:29,961,120...29,988,959
JBrowse link
G Rad50 RAD50 double strand break repair protein multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of RAD50 mRNA CTD PMID:18253720 NCBI chr10:39,002,130...39,054,042
Ensembl chr10:39,001,498...39,054,142
JBrowse link
G Rad51b RAD51 paralog B increases expression ISO Fenofibrate results in increased expression of RAD51B mRNA CTD PMID:11798191 NCBI chr 6:102,473,978...103,018,185
Ensembl chr 6:102,477,036...102,512,505
JBrowse link
G Raet1e retinoic acid early transcript 1E increases expression ISO Fenofibrate results in increased expression of RAET1E mRNA CTD PMID:11798191 NCBI chr 1:1,101,666...1,120,340
Ensembl chr 1:1,101,965...1,116,926
JBrowse link
G Ramp2 receptor activity modifying protein 2 decreases expression ISO Fenofibrate results in decreased expression of RAMP2 mRNA CTD PMID:11798191 NCBI chr10:89,166,170...89,168,962
Ensembl chr10:89,166,890...89,168,965
JBrowse link
G Rara retinoic acid receptor, alpha multiple interactions
decreases expression
EXP
ISO
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of RARA mRNA
Fenofibrate results in decreased expression of RARA mRNA
CTD PMID:18253720, PMID:25596134 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Rarb retinoic acid receptor, beta multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of RARB mRNA CTD PMID:18253720 NCBI chr15:9,915,223...10,262,599
Ensembl chr15:10,120,206...10,262,599
JBrowse link
G Rbx1 ring-box 1 decreases expression ISO Fenofibrate results in decreased expression of RBX1 mRNA CTD PMID:21318169 NCBI chr 7:122,700,849...122,710,907
Ensembl chr 7:122,700,854...122,709,935
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO
EXP
Fenofibrate affects the localization of and results in decreased activity of RELA protein; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of RELA protein]; Fenofibrate inhibits the reaction [Glucose results in increased expression of RELA protein]; Fenofibrate results in decreased localization of and results in decreased activity of RELA protein
[Fenofibrate co-treated with Sodium Glutamate] results in increased expression of RELA protein
CTD PMID:16600694, PMID:20520642, PMID:20580385, PMID:21999347, PMID:25545733 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Retsat retinol saturase increases expression ISO Fenofibrate results in increased expression of RETSAT mRNA CTD PMID:11798191 NCBI chr 4:100,465,365...100,474,128
Ensembl chr 4:100,465,170...100,474,301
JBrowse link
G Rlf RLF zinc finger increases expression EXP Fenofibrate results in increased expression of RLF mRNA CTD PMID:25596134 NCBI chr 5:140,107,144...140,162,698
Ensembl chr 5:140,107,275...140,162,642
JBrowse link
G Rnd1 Rho family GTPase 1 decreases expression EXP Fenofibrate results in decreased expression of RND1 mRNA CTD PMID:25596134 NCBI chr 7:140,349,138...140,356,209
Ensembl chr 7:140,349,138...140,356,209
JBrowse link
G Rnd3 Rho family GTPase 3 decreases expression EXP Fenofibrate results in decreased expression of RND3 mRNA CTD PMID:25596134 NCBI chr 3:36,643,374...36,660,727
Ensembl chr 3:36,642,587...36,660,758
JBrowse link
G Rnf125 ring finger protein 125 increases expression ISO Fenofibrate results in increased expression of RNF125 mRNA CTD PMID:21318169 NCBI chr18:15,193,226...15,225,454
Ensembl chr18:15,192,962...15,225,427
JBrowse link
G Rnf14 ring finger protein 14 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of RNF14 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of RNF14 mRNA]
CTD PMID:21318169 NCBI chr18:31,443,424...31,468,641
Ensembl chr18:31,444,472...31,468,640
JBrowse link
G Rnf144b ring finger protein 144B decreases expression
multiple interactions
ISO Fenofibrate results in decreased expression of RNF144B mRNA
PPARA protein affects the reaction [Fenofibrate results in decreased expression of RNF144B mRNA]
CTD PMID:21318169 NCBI chr17:17,817,122...17,947,777
Ensembl chr17:17,817,100...17,947,777
JBrowse link
G Rnf19a ring finger protein 19A, RBR E3 ubiquitin protein ligase increases expression ISO Fenofibrate results in increased expression of RNF19A mRNA CTD PMID:21318169 NCBI chr 7:75,058,758...75,098,331
Ensembl chr 7:75,058,758...75,098,331
JBrowse link
G Ro60 Ro60, Y RNA binding protein decreases expression ISO Fenofibrate results in decreased expression of RO60 mRNA CTD PMID:25596134 NCBI chr13:60,546,892...60,567,882
Ensembl chr13:60,546,912...60,567,882
JBrowse link
G Rsrc2 arginine and serine rich coiled-coil 2 decreases expression EXP Fenofibrate results in decreased expression of RSRC2 mRNA CTD PMID:25596134 NCBI chr12:38,274,290...38,294,294
Ensembl chr12:38,274,297...38,294,292
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 decreases expression ISO Fenofibrate results in decreased expression of H2-EB1 mRNA CTD PMID:11798191 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190
JBrowse link
G Rxra retinoid X receptor alpha decreases expression
affects expression
ISO
EXP
Fenofibrate results in decreased expression of RXRA mRNA
Fenofibrate affects the expression of RXRA mRNA
CTD PMID:25596134 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G S100a10 S100 calcium binding protein A10 increases expression ISO Fenofibrate results in increased expression of S100A10 mRNA CTD PMID:11798191 NCBI chr 2:193,892,589...193,901,236
Ensembl chr 2:193,892,589...193,901,236
JBrowse link
G Sars1 seryl-tRNA synthetase 1 increases expression EXP Fenofibrate results in increased expression of SARS1 mRNA CTD PMID:25596134 NCBI chr 2:211,219,743...211,235,475
Ensembl chr 2:211,219,750...211,235,467
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 increases expression EXP Fenofibrate results in increased expression of SAT1 mRNA CTD PMID:25596134 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
G Scamp1 secretory carrier membrane protein 1 decreases expression EXP Fenofibrate results in decreased expression of SCAMP1 mRNA CTD PMID:25596134 NCBI chr 2:23,858,021...23,941,128
Ensembl chr 2:23,857,995...23,941,084
JBrowse link
G Scarb1 scavenger receptor class B, member 1 multiple interactions
decreases activity
increases expression
ISO [Aspirin co-treated with Fenofibrate] results in increased expression of SCARB1 protein
Fenofibrate results in decreased activity of SCARB1 protein
Fenofibrate inhibits the reaction [SCARB1 protein results in increased export of Cholesterol, HDL]; Fenofibrate inhibits the reaction [SCARB1 protein results in increased uptake of cholesteryl oleyl ether]
Fenofibrate results in increased expression of SCARB1 protein
CTD PMID:16816107, PMID:17533223 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions
affects expression
increases expression
ISO
EXP
[Oleic Acid co-treated with Fenofibrate] results in increased expression of SCD1 mRNA
Fenofibrate affects the expression of SCD mRNA
Fenofibrate results in increased expression of SCD1 mRNA
NR1H2 gene mutant form affects the reaction [Fenofibrate results in increased expression of SCD1 mRNA]; NR1H3 gene mutant form affects the reaction [Fenofibrate results in increased expression of SCD1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD1 mRNA]
CTD PMID:23063693, PMID:24534255, PMID:27665778 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of SCD mRNA; Fenofibrate results in increased expression of SCD2 mRNA
NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA]
CTD PMID:17118139, PMID:23063693 NCBI chr 1:264,059,374...264,072,433
Ensembl chr 1:264,059,374...264,072,433
JBrowse link
G Scly selenocysteine lyase affects expression EXP Fenofibrate affects the expression of SCLY mRNA CTD PMID:20801182 NCBI chr 9:98,438,408...98,459,075
Ensembl chr 9:98,438,439...98,459,080
JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B increases expression ISO Fenofibrate results in increased expression of SDHB protein CTD PMID:24752549 NCBI chr 5:159,484,378...159,505,063
Ensembl chr 5:159,484,370...159,505,064
JBrowse link
G Sec63 SEC63 homolog, protein translocation regulator increases expression
multiple interactions
ISO Fenofibrate results in increased expression of SEC63 mRNA
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of SEC63 mRNA
CTD PMID:21318169 NCBI chr20:47,494,270...47,563,222
Ensembl chr20:47,494,270...47,563,222
JBrowse link
G Sele selectin E multiple interactions ISO dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of SELE mRNA]]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of SELE mRNA] CTD PMID:20580385 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
JBrowse link
G Sema6b semaphorin 6B multiple interactions
decreases expression
ISO alitretinoin promotes the reaction [Fenofibrate results in decreased expression of SEMA6B mRNA]; alitretinoin promotes the reaction [Fenofibrate results in decreased expression of SEMA6B protein]
Fenofibrate results in decreased expression of SEMA6B mRNA; Fenofibrate results in decreased expression of SEMA6B protein
CTD PMID:16525649 NCBI chr 9:10,934,273...10,951,252
Ensembl chr 9:10,941,613...10,951,252
JBrowse link
G Senp2 SUMO specific peptidase 2 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of SENP2 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of SENP2 mRNA]
CTD PMID:21318169 NCBI chr11:82,627,973...82,664,702
Ensembl chr11:82,630,436...82,664,630
JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N affects expression EXP Fenofibrate affects the expression of SERPINA3N mRNA CTD PMID:20801182 NCBI chr 6:128,073,344...128,080,878
Ensembl chr 6:127,941,526...128,080,889
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions
affects expression
ISO
EXP
Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [SMAD4 protein results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD4 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]]
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of SERPINE1 mRNA
Fenofibrate affects the expression of SERPINE1 mRNA
Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA]]
CTD PMID:18253720, PMID:19593819, PMID:20801182 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Sertad1 SERTA domain containing 1 decreases expression EXP Fenofibrate results in decreased expression of SERTAD1 mRNA CTD PMID:25596134 NCBI chr 1:84,293,102...84,296,370
Ensembl chr 1:84,293,102...84,296,367
JBrowse link
G Sesn1 sestrin 1 decreases expression EXP Fenofibrate results in decreased expression of SESN1 mRNA CTD PMID:25596134 NCBI chr20:46,667,116...46,758,306
Ensembl chr20:46,667,121...46,758,305
JBrowse link
G Sgk2 serum/glucocorticoid regulated kinase 2 increases expression ISO Fenofibrate results in increased expression of SGK2 mRNA CTD PMID:25572481 NCBI chr 3:159,361,313...159,385,843
Ensembl chr 3:159,368,273...159,384,775
JBrowse link
G Sh3bgrl2 SH3 domain binding glutamate-rich protein like 2 increases expression ISO Fenofibrate results in increased expression of SH3BGRL2 mRNA CTD PMID:25572481 NCBI chr 8:91,069,925...91,162,537
Ensembl chr 8:91,070,073...91,160,258
JBrowse link
G Sh3tc1 SH3 domain and tetratricopeptide repeats 1 increases expression ISO Fenofibrate results in increased expression of SH3TC1 mRNA CTD PMID:25596134 NCBI chr14:80,184,814...80,229,207
Ensembl chr14:80,195,715...80,229,214
JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 affects expression EXP Fenofibrate affects the expression of SIAH2 mRNA CTD PMID:25596134 NCBI chr 2:148,874,151...148,891,900
Ensembl chr 2:148,874,151...148,891,900
JBrowse link
G Sik1 salt-inducible kinase 1 increases expression
decreases expression
ISO
EXP
Fenofibrate results in increased expression of SIK1 mRNA
Fenofibrate results in decreased expression of SIK1 mRNA
CTD PMID:25596134 NCBI chr20:10,670,747...10,680,279
Ensembl chr20:10,668,411...10,680,283
JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor decreases expression EXP Fenofibrate results in decreased expression of SIVA1 mRNA CTD PMID:25596134 NCBI chr 6:137,209,999...137,214,379
Ensembl chr 6:137,210,052...137,214,388
JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression ISO
EXP
Fenofibrate results in decreased expression of SLC10A1 mRNA CTD PMID:25572481, PMID:27765674 NCBI chr 6:104,617,730...104,631,355
Ensembl chr 6:104,617,730...104,631,355
JBrowse link
G Slc16a13 solute carrier family 16, member 13 increases expression ISO Fenofibrate results in increased expression of SLC16A13 mRNA CTD PMID:25572481 NCBI chr10:56,827,591...56,831,324
Ensembl chr10:56,827,594...56,831,243
JBrowse link
G Slc16a6 solute carrier family 16, member 6 increases expression EXP Fenofibrate results in increased expression of SLC16A6 mRNA CTD PMID:25596134 NCBI chr10:97,733,701...97,758,723
Ensembl chr10:97,735,548...97,756,521
JBrowse link
G Slc1a7 solute carrier family 1 member 7 increases expression ISO Fenofibrate results in increased expression of SLC1A7 mRNA CTD PMID:25596134 NCBI chr 5:127,571,114...127,616,033
Ensembl chr 5:127,571,114...127,616,033
JBrowse link
G Slc22a5 solute carrier family 22 member 5 increases expression EXP Fenofibrate results in increased expression of SLC22A5 mRNA CTD PMID:27665778 NCBI chr10:39,201,101...39,228,090
Ensembl chr10:39,201,107...39,323,853
JBrowse link
G Slc25a20 solute carrier family 25 member 20 increases expression EXP
ISO
Fenofibrate results in increased expression of SLC25A20 mRNA CTD PMID:16707586, PMID:25572481, PMID:25596134 NCBI chr 8:117,455,308...117,476,762
Ensembl chr 8:117,455,262...117,476,734
JBrowse link
G Slc25a34 solute carrier family 25, member 34 increases expression ISO Fenofibrate results in increased expression of SLC25A34 mRNA CTD PMID:25572481 NCBI chr 5:160,175,206...160,179,978
Ensembl chr 5:160,176,124...160,179,978
JBrowse link
G Slc25a4 solute carrier family 25 member 4 decreases expression EXP Fenofibrate results in decreased expression of SLC25A4 protein CTD PMID:20118634 NCBI chr16:49,266,903...49,270,698
Ensembl chr16:49,266,903...49,270,698
JBrowse link
G Slc27a1 solute carrier family 27 member 1 increases expression ISO Fenofibrate results in increased expression of SLC27A1 mRNA CTD PMID:11798191 NCBI chr16:19,997,823...20,016,193
Ensembl chr16:19,999,112...20,016,190
JBrowse link
G Slc27a2 solute carrier family 27 member 2 increases expression ISO
EXP
Fenofibrate results in increased expression of SLC27A2 mRNA CTD PMID:17118139, PMID:25572481, PMID:27665778 NCBI chr 3:119,014,620...119,052,531
Ensembl chr 3:119,014,620...119,052,531
JBrowse link
G Slc27a4 solute carrier family 27 member 4 multiple interactions
increases expression
ISO PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SLC27A4 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SLC27A4 protein]
Fenofibrate results in increased expression of SLC27A4 mRNA; Fenofibrate results in increased expression of SLC27A4 protein
PPARA protein promotes the reaction [Fenofibrate results in increased expression of SLC27A4 protein]
CTD PMID:24752549 NCBI chr 3:8,363,937...8,376,858
Ensembl chr 3:8,363,937...8,376,858
JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression ISO
EXP
Fenofibrate results in increased expression of SLC3A2 mRNA CTD PMID:25596134 NCBI chr 1:224,906,566...224,921,029
Ensembl chr 1:224,906,554...224,921,092
JBrowse link
G Slc6a9 solute carrier family 6 member 9 decreases expression
increases expression
EXP
ISO
Fenofibrate results in decreased expression of SLC6A9 mRNA
Fenofibrate results in increased expression of SLC6A9 mRNA
CTD PMID:25596134 NCBI chr 5:136,669,674...136,703,702
Ensembl chr 5:136,669,674...136,703,697
JBrowse link
G Slc7a1 solute carrier family 7 member 1 increases expression EXP
ISO
Fenofibrate results in increased expression of SLC7A1 mRNA CTD PMID:25596134 NCBI chr12:8,032,775...8,108,972
Ensembl chr12:8,032,809...8,108,972
JBrowse link
G Slc7a5 solute carrier family 7 member 5 increases expression ISO Fenofibrate results in increased expression of SLC7A5 mRNA CTD PMID:25596134 NCBI chr19:54,693,959...54,722,563
Ensembl chr19:54,693,959...54,722,563
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 decreases expression ISO
EXP
Fenofibrate results in decreased expression of SLCO2B1 mRNA CTD PMID:25596134 NCBI chr 1:164,623,313...164,671,612
Ensembl chr 1:164,623,599...164,671,577
JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]] CTD PMID:19593819 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Smad4 SMAD family member 4 multiple interactions ISO Fenofibrate inhibits the reaction [SMAD4 protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD4 protein results in increased expression of SERPINE1 mRNA]] CTD PMID:19593819 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 multiple interactions ISO Fenofibrate promotes the reaction [Dextran Sulfate results in decreased expression of SMPD2 mRNA] CTD PMID:25035112 NCBI chr20:46,212,070...46,215,183
Ensembl chr20:46,211,892...46,215,120
JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of SMPD3 mRNA
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of SMPD3 mRNA
CTD PMID:21318169 NCBI chr19:38,237,963...38,321,572
Ensembl chr19:38,237,965...38,321,528
JBrowse link
G Smpd4 sphingomyelin phosphodiesterase 4 multiple interactions ISO Fenofibrate promotes the reaction [Dextran Sulfate results in decreased expression of SMPD4 mRNA] CTD PMID:25035112 NCBI chr11:87,522,971...87,546,687
Ensembl chr11:87,522,971...87,546,687
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions EXP [Fenofibrate co-treated with Resveratrol] inhibits the reaction [Fructose results in increased expression of SOCS3 mRNA]; Fenofibrate inhibits the reaction [Fructose results in increased expression of SOCS3 mRNA] CTD PMID:26973390 NCBI chr10:106,973,863...106,976,969
Ensembl chr10:106,975,178...106,976,040
JBrowse link
G Socs6 suppressor of cytokine signaling 6 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of SOCS6 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of SOCS6 mRNA]
CTD PMID:21318169 NCBI chr18:85,962,729...85,981,125
Ensembl chr18:85,962,729...85,980,833
JBrowse link
G Socs7 suppressor of cytokine signaling 7 decreases expression ISO Fenofibrate results in decreased expression of SOCS7 mRNA CTD PMID:21318169 NCBI chr10:85,301,797...85,337,971
Ensembl chr10:85,301,875...85,330,397
JBrowse link
G Sod2 superoxide dismutase 2 increases expression EXP Fenofibrate results in increased expression of SOD2 mRNA CTD PMID:17264098 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Son SON DNA and RNA binding protein decreases expression EXP Fenofibrate results in decreased expression of SON mRNA CTD PMID:25596134 NCBI chr11:31,806,598...31,837,769
Ensembl chr11:31,806,618...31,837,763
JBrowse link
G Sorl1 sortilin related receptor 1 increases expression
decreases expression
EXP
ISO
Fenofibrate results in increased expression of SORL1 mRNA
Fenofibrate results in decreased expression of SORL1 mRNA
CTD PMID:25596134 NCBI chr 8:46,228,077...46,287,171 JBrowse link
G Sort1 sortilin 1 increases expression ISO Fenofibrate results in increased expression of SORT1 mRNA CTD PMID:24986865 NCBI chr 2:211,078,092...211,156,312
Ensembl chr 2:211,078,334...211,156,312
JBrowse link
G Spns2 sphingolipid transporter 2 increases expression ISO Fenofibrate results in increased expression of SPNS2 mRNA CTD PMID:25572481 NCBI chr10:59,010,428...59,049,482
Ensembl chr10:59,010,428...59,049,482
JBrowse link
G Spop speckle type BTB/POZ protein increases expression
multiple interactions
ISO Fenofibrate results in increased expression of SPOP mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of SPOP mRNA]
CTD PMID:21318169 NCBI chr10:83,231,187...83,311,987
Ensembl chr10:83,231,238...83,311,592
JBrowse link
G Spsb1 splA/ryanodine receptor domain and SOCS box containing 1 increases expression EXP Fenofibrate results in increased expression of SPSB1 mRNA CTD PMID:25596134 NCBI chr 5:166,913,734...166,978,534
Ensembl chr 5:166,913,735...166,926,636
JBrowse link
G Sqle squalene epoxidase increases expression
multiple interactions
ISO Fenofibrate results in increased expression of SQLE mRNA
NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SQLE mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SQLE mRNA]
CTD PMID:23063693 NCBI chr 7:99,609,929...99,624,803
Ensembl chr 7:99,609,191...99,624,732
JBrowse link
G Sqstm1 sequestosome 1 increases expression EXP Fenofibrate results in increased expression of SQSTM1 mRNA CTD PMID:25596134 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Srd5a3 steroid 5 alpha-reductase 3 decreases expression EXP Fenofibrate results in decreased expression of SRD5A3 mRNA CTD PMID:25596134 NCBI chr14:34,554,769...34,570,423
Ensembl chr14:34,556,220...34,570,356
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions
increases expression
ISO
EXP
Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SREBF1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SREBF1 mRNA]]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SREBF1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SREBF1 mRNA]
Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in increased expression of SREBF1 mRNA]; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in increased expression of SREBF1 protein]
[Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in increased expression of SREBF1 mRNA]
CTD PMID:19593819, PMID:23063693, PMID:24735863, PMID:26973390 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Fenofibrate results in increased expression of SRXN1 mRNA CTD PMID:25596134 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G St3gal4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 decreases expression ISO Fenofibrate results in decreased expression of ST3GAL4 mRNA CTD PMID:11798191 NCBI chr 8:36,264,741...36,314,811
Ensembl chr 8:36,264,750...36,314,811
JBrowse link
G Stat5b signal transducer and activator of transcription 5B decreases activity ISO Fenofibrate results in decreased activity of STAT5B protein CTD PMID:30114225 NCBI chr10:88,686,207...88,712,313
Ensembl chr10:88,686,207...88,754,829
JBrowse link
G Stk11 serine/threonine kinase 11 multiple interactions ISO Fenofibrate results in increased expression of and results in increased phosphorylation of STK11 protein CTD PMID:25545733 NCBI chr 7:12,440,751...12,457,513
Ensembl chr 7:12,440,751...12,457,513
JBrowse link
G Strbp spermatid perinuclear RNA binding protein increases expression ISO Fenofibrate results in increased expression of STRBP mRNA CTD PMID:25596134 NCBI chr 3:21,817,680...21,956,988
Ensembl chr 3:21,828,298...21,904,270
JBrowse link
G Suclg1 succinate-CoA ligase GDP/ADP-forming subunit alpha affects expression
increases expression
EXP
ISO
Fenofibrate affects the expression of SUCLG1 mRNA
Fenofibrate results in increased expression of SUCLG1 protein
Fenofibrate results in increased expression of SUCLG1 mRNA
CTD PMID:16707586, PMID:20801182, PMID:24752549 NCBI chr 4:101,181,315...101,210,692
Ensembl chr 4:101,180,404...101,210,746
JBrowse link
G Sulf2 sulfatase 2 decreases expression ISO
EXP
Fenofibrate results in decreased expression of SULF2 mRNA CTD PMID:25596134 NCBI chr 3:162,791,349...162,872,984
Ensembl chr 3:162,791,355...162,872,831
JBrowse link
G Sult1c2a sulfotransferase family, cytosolic, 1C, member 2a multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of SULT1C2 mRNA CTD PMID:18253720 NCBI chr 9:4,152,588...4,168,355
Ensembl chr 9:4,152,589...4,168,221
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of SULT1E1 mRNA CTD PMID:18253720 NCBI chr14:22,070,861...22,089,264
Ensembl chr14:22,072,024...22,089,248
JBrowse link
G Sult4a1 sulfotransferase family 4A, member 1 multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of SULT4A1 mRNA CTD PMID:18253720 NCBI chr 7:124,958,546...124,982,602
Ensembl chr 7:124,958,546...124,982,566
JBrowse link
G Taldo1 transaldolase 1 decreases expression EXP Fenofibrate results in decreased expression of TALDO1 mRNA CTD PMID:25596134 NCBI chr 1:214,375,555...214,385,886
Ensembl chr 1:214,375,515...214,385,885
JBrowse link
G Tars1 threonyl-tRNA synthetase 1 decreases expression EXP Fenofibrate results in decreased expression of TARS1 mRNA CTD PMID:25596134 NCBI chr 2:61,394,632...61,414,115
Ensembl chr 2:61,394,770...61,414,102
JBrowse link
G Tcp1 t-complex 1 multiple interactions EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of TCP1 mRNA CTD PMID:18253720 NCBI chr 1:48,025,664...48,033,343
Ensembl chr 1:48,025,663...48,033,396
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase increases expression ISO Fenofibrate results in increased expression of TDO2 mRNA CTD PMID:25572481 NCBI chr 2:180,897,059...180,914,919
Ensembl chr 2:180,897,011...180,914,940
JBrowse link
G Tfe3 transcription factor binding to IGHM enhancer 3 affects expression
increases expression
EXP
ISO
Fenofibrate affects the expression of TFE3 mRNA
Fenofibrate results in increased expression of TFE3 mRNA
CTD PMID:25596134 NCBI chr  X:15,574,579...15,587,826
Ensembl chr  X:15,575,934...15,587,419
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO
EXP
Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]
[Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in increased expression of TGFB1 mRNA]; Fenofibrate inhibits the reaction [Fructose results in increased expression of TGFB1 mRNA]
Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TGFB1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in decreased expression of TRIB3 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of IL6 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 mRNA]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of IL6 mRNA]]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TGFB1 mRNA]]
CTD PMID:19593819, PMID:26973390 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Thrsp thyroid hormone responsive multiple interactions
decreases expression
ISO Fenofibrate promotes the reaction [Oleic Acid results in decreased expression of THRSP mRNA]
Fenofibrate results in decreased expression of THRSP mRNA
CTD PMID:24534255, PMID:25572481 NCBI chr 1:162,381,251...162,385,575
Ensembl chr 1:162,381,253...162,385,575
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 mRNA]; Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of TIMP1 mRNA]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]] CTD PMID:19593819, PMID:28871336 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 multiple interactions ISO Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of TIMP2 mRNA] CTD PMID:28871336 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072
JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase increases expression EXP Fenofibrate results in increased expression of TIPARP mRNA CTD PMID:25596134 NCBI chr 2:157,316,293...157,342,979
Ensembl chr 2:157,316,266...157,341,469
JBrowse link
G Tmem120a transmembrane protein 120A decreases expression ISO Fenofibrate results in decreased expression of TMEM120A mRNA CTD PMID:25572481 NCBI chr12:23,989,596...23,998,257
Ensembl chr12:23,989,596...23,998,254
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
decreases response to substance
ISO
EXP
Fenofibrate inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; Fenofibrate inhibits the reaction [TNF protein results in increased expression of CCL5 protein]; Fenofibrate inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]]
[Fenofibrate co-treated with Resveratrol] inhibits the reaction [Fructose results in increased expression of and results in increased secretion of TNF protein]; [Fenofibrate co-treated with Sodium Glutamate] results in increased expression of TNF protein; Fenofibrate inhibits the reaction [Fructose results in increased expression of and results in increased secretion of TNF protein]
Fenofibrate results in decreased expression of TNF mRNA; Fenofibrate results in decreased expression of TNF protein
[Fenofibrate co-treated with Alitretinoin] inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF mRNA]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Fenofibrate inhibits the reaction [triptolide results in increased expression of TNF mRNA]; Fenofibrate promotes the reaction [Dextran Sulfate results in increased expression of TNF protein]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF mRNA]]
Fenofibrate results in decreased susceptibility to TNF protein; TNF protein results in decreased susceptibility to Fenofibrate
CTD PMID:12586603, PMID:15968640, PMID:18356826, PMID:19593819, PMID:20520642, PMID:21300114, PMID:21999347, PMID:25035112, PMID:26973390, PMID:31241159 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B decreases expression ISO Fenofibrate results in decreased expression of TNFRSF11B mRNA CTD PMID:25572481 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665
JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 increases expression ISO Fenofibrate results in increased expression of TNFRSF21 mRNA CTD PMID:25572481, PMID:25596134 NCBI chr 9:20,546,159...20,621,051
Ensembl chr 9:20,546,159...20,621,051
JBrowse link
G Top1 DNA topoisomerase I multiple interactions
increases expression
EXP [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of TOP1 mRNA
Fenofibrate results in increased expression of TOP1 mRNA
CTD PMID:18253720, PMID:25596134 NCBI chr 3:156,635,688...156,717,686
Ensembl chr 3:156,642,464...156,717,686
JBrowse link
G Topors TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase increases expression
multiple interactions
ISO Fenofibrate results in increased expression of TOPORS mRNA
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of TOPORS mRNA
CTD PMID:21318169 NCBI chr 5:56,554,956...56,566,503
Ensembl chr 5:56,554,969...56,567,320
JBrowse link
G Tor1b torsin family 1, member B increases expression
multiple interactions
ISO Fenofibrate results in increased expression of TOR1B mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of TOR1B mRNA]
CTD PMID:21318169 NCBI chr 3:9,792,818...9,798,924
Ensembl chr 3:9,792,899...9,798,923
JBrowse link
G Tor3a torsin family 3, member A increases expression
multiple interactions
ISO Fenofibrate results in increased expression of TOR3A mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of TOR3A mRNA]
CTD PMID:21318169 NCBI chr13:74,246,504...74,277,694
Ensembl chr13:74,252,405...74,276,964
JBrowse link
G Tp53 tumor protein p53 increases expression
affects activity
EXP
ISO
Fenofibrate results in increased expression of TP53 mRNA
Fenofibrate affects the activity of TP53 protein
CTD PMID:17264098, PMID:25596134 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 decreases expression ISO Fenofibrate results in decreased expression of TP53I3 mRNA CTD PMID:25596134 NCBI chr13:75,101,759...75,145,967
Ensembl chr13:75,105,615...75,143,441
JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 increases expression
affects expression
decreases expression
EXP
ISO
Fenofibrate results in increased expression of TRP53INP1 mRNA
Fenofibrate affects the expression of TP53INP1 mRNA
Fenofibrate results in decreased expression of TP53INP1 mRNA
CTD PMID:17264098, PMID:25596134 NCBI chr 5:24,402,895...24,419,651
Ensembl chr 5:24,410,863...24,416,888
JBrowse link
G Trafd1 TRAF type zinc finger domain containing 1 decreases expression EXP Fenofibrate results in decreased expression of TRAFD1 mRNA CTD PMID:25596134 NCBI chr12:40,695,520...40,709,438
Ensembl chr12:40,695,520...40,709,462
JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 decreases expression ISO Fenofibrate results in decreased expression of TRIAP1 mRNA CTD PMID:25596134 NCBI chr12:46,987,404...46,989,906
Ensembl chr12:46,987,404...46,989,897
Ensembl chr12:46,987,404...46,989,897
JBrowse link
G Trib3 tribbles pseudokinase 3 multiple interactions ISO [Fenofibrate results in increased activity of PPARA protein] which results in increased expression of TRIB3 mRNA; Fenofibrate inhibits the reaction [TGFB1 protein results in decreased expression of TRIB3 mRNA] CTD PMID:19593819 NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
JBrowse link
G Trim24 tripartite motif-containing 24 increases expression ISO Fenofibrate results in increased expression of TRIM24 mRNA CTD PMID:25572481 NCBI chr 4:65,632,278...65,684,746
Ensembl chr 4:65,637,407...65,684,743
JBrowse link
G Trip12 thyroid hormone receptor interactor 12 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of TRIP12 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of TRIP12 mRNA]
CTD PMID:21318169 NCBI chr 9:92,305,059...92,435,388
Ensembl chr 9:92,305,051...92,435,365
JBrowse link
G Txnip thioredoxin interacting protein increases expression EXP
ISO
Fenofibrate results in increased expression of TXNIP mRNA CTD PMID:17264098, PMID:25572481 NCBI chr 2:198,683,168...198,686,971
Ensembl chr 2:198,683,159...198,686,974
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Fenofibrate results in increased expression of TXNRD1 mRNA CTD PMID:25596134 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Tyr tyrosinase multiple interactions
decreases expression
ISO [Fenofibrate results in decreased chemical synthesis of Melanins] which results in decreased expression of TYR; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Fenofibrate results in decreased expression of TYR protein]; Fenofibrate results in decreased expression of and results in decreased activity of TYR protein
Fenofibrate results in decreased expression of TYR mRNA
CTD PMID:23872139 NCBI chr 1:151,012,598...151,106,802
Ensembl chr 1:151,012,598...151,106,802
JBrowse link
G Uba5 ubiquitin-like modifier activating enzyme 5 decreases expression ISO Fenofibrate results in decreased expression of UBA5 mRNA CTD PMID:21318169 NCBI chr 8:112,578,607...112,594,192
Ensembl chr 8:112,578,590...112,594,261
JBrowse link
G Ube2g2 ubiquitin-conjugating enzyme E2G 2 affects expression EXP Fenofibrate affects the expression of UBE2G2 mRNA CTD PMID:25596134 NCBI chr20:11,700,089...11,721,823
Ensembl chr20:11,700,089...11,721,838
JBrowse link
G Ube2q2 ubiquitin conjugating enzyme E2 Q2 multiple interactions
increases expression
ISO PPARA protein affects the reaction [Fenofibrate results in increased expression of UBE2Q2 mRNA] CTD PMID:21318169 NCBI chr 8:59,709,972...59,754,102
Ensembl chr 8:59,711,549...59,766,889
JBrowse link
G Ube2r2 ubiquitin-conjugating enzyme E2R 2 decreases expression
multiple interactions
ISO Fenofibrate results in decreased expression of UBE2R2 mRNA
PPARA protein affects the reaction [Fenofibrate results in decreased expression of UBE2R2 mRNA]
CTD PMID:21318169 NCBI chr 5:57,472,315...57,530,973
Ensembl chr 5:57,472,315...57,530,987
JBrowse link
G Ube2w ubiquitin-conjugating enzyme E2W increases expression ISO Fenofibrate results in increased expression of UBE2W mRNA CTD PMID:21318169 NCBI chr 5:29,798,845...29,812,777 JBrowse link
G Ube3a ubiquitin protein ligase E3A increases expression
multiple interactions
ISO Fenofibrate results in increased expression of UBE3A mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of UBE3A mRNA]
CTD PMID:21318169 NCBI chr 1:116,586,901...116,678,161
Ensembl chr 1:116,587,815...116,679,973
JBrowse link
G Ubr2 ubiquitin protein ligase E3 component n-recognin 2 multiple interactions
increases expression
ISO [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of UBR2 mRNA
Fenofibrate results in increased expression of UBR2 mRNA
CTD PMID:21318169 NCBI chr 9:16,003,058...16,080,152
Ensembl chr 9:16,003,058...16,080,152
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions
increases expression
EXP
ISO
[Fenofibrate binds to and results in increased activity of PPARA protein] which results in increased expression of UCP2 mRNA; [Fenofibrate co-treated with Sodium Glutamate] results in increased expression of UCP2 mRNA
Fenofibrate results in increased expression of UCP2 mRNA; Fenofibrate results in increased expression of UCP2 protein
PPARA protein promotes the reaction [Fenofibrate results in increased expression of UCP2 protein]
PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of UCP2 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of UCP2 protein]
CTD PMID:11341955, PMID:16595124, PMID:21999347, PMID:24752549 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
JBrowse link
G Ucp3 uncoupling protein 3 increases expression EXP Fenofibrate results in increased expression of UCP3 mRNA CTD PMID:16595124 NCBI chr 1:165,482,912...165,495,895
Ensembl chr 1:165,482,155...165,496,206
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression ISO Fenofibrate results in increased expression of UGT1A1 mRNA CTD PMID:25572481 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases expression ISO Fenofibrate results in increased expression of UGT1A3 mRNA CTD PMID:17058234 NCBI chr 9:95,285,592...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 multiple interactions
increases expression
EXP [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of UGT1A6 mRNA
Fenofibrate results in increased expression of UGT1A6 mRNA
CTD PMID:18253720, PMID:18775883 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Uri1 URI1, prefoldin-like chaperone increases expression
multiple interactions
ISO Fenofibrate results in increased expression of URI1 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of URI1 mRNA]
CTD PMID:21318169 NCBI chr 1:94,346,513...94,404,362
Ensembl chr 1:94,346,514...94,404,211
JBrowse link
G Urm1 ubiquitin related modifier 1 decreases expression
multiple interactions
ISO Fenofibrate results in decreased expression of URM1 mRNA
PPARA protein affects the reaction [Fenofibrate results in decreased expression of URM1 mRNA]
CTD PMID:21318169 NCBI chr 3:8,389,024...8,405,868
Ensembl chr 3:8,389,024...8,405,868
JBrowse link
G Usp1 ubiquitin specific peptidase 1 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of USP1 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of USP1 mRNA]
CTD PMID:21318169 NCBI chr 5:117,583,502...117,594,872
Ensembl chr 5:117,583,502...117,594,870
JBrowse link
G Usp10 ubiquitin specific peptidase 10 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of USP10 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of USP10 mRNA]
CTD PMID:21318169 NCBI chr19:52,566,274...52,608,820
Ensembl chr19:52,566,607...52,608,817
JBrowse link
G Usp22 ubiquitin specific peptidase 22 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of USP22 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of USP22 mRNA]
CTD PMID:21318169 NCBI chr10:47,429,201...47,453,298
Ensembl chr10:47,429,002...47,453,442
JBrowse link
G Usp3 ubiquitin specific peptidase 3 increases expression EXP Fenofibrate results in increased expression of USP3 mRNA CTD PMID:25596134 NCBI chr 8:72,207,970...72,284,871
Ensembl chr 8:72,207,972...72,284,873
JBrowse link
G Usp36 ubiquitin specific peptidase 36 decreases expression
multiple interactions
ISO Fenofibrate results in decreased expression of USP36 mRNA
PPARA protein affects the reaction [Fenofibrate results in decreased expression of USP36 mRNA]
CTD PMID:21318169 NCBI chr10:107,292,828...107,324,355
Ensembl chr10:107,292,828...107,324,355
JBrowse link
G Usp38 ubiquitin specific peptidase 38 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of USP38 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of USP38 mRNA]
CTD PMID:21318169 NCBI chr19:30,668,258...30,699,852
Ensembl chr19:30,668,602...30,699,859
JBrowse link
G Usp7 ubiquitin specific peptidase 7 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of USP7 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of USP7 mRNA]
CTD PMID:21318169 NCBI chr10:6,930,462...7,019,910
Ensembl chr10:6,975,244...7,018,930
JBrowse link
G Usp9x ubiquitin specific peptidase 9, X-linked increases expression
multiple interactions
ISO Fenofibrate results in increased expression of USP9X mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of USP9X mRNA]
CTD PMID:21318169 NCBI chr  X:10,510,033...10,660,555
Ensembl chr  X:10,510,033...10,630,297
JBrowse link
G Uspl1 ubiquitin specific peptidase like 1 increases expression
multiple interactions
ISO Fenofibrate results in increased expression of USPL1 mRNA
PPARA protein affects the reaction [Fenofibrate results in increased expression of USPL1 mRNA]
CTD PMID:21318169 NCBI chr12:6,930,018...6,957,027
Ensembl chr12:6,929,978...6,956,984
JBrowse link
G Vars1 valyl-tRNA synthetase 1 increases expression EXP
ISO
Fenofibrate results in increased expression of VARS1 mRNA CTD PMID:25596134 NCBI chr20:4,993,539...5,008,259
Ensembl chr20:4,993,560...5,008,262