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Gene: Ucp3 (uncoupling protein 3 (mitochondrial, proton carrier)) Mus musculus
Symbol: Ucp3
Name: uncoupling protein 3 (mitochondrial, proton carrier)
RGD ID: 11474
Description: Exhibits oxidative phosphorylation uncoupler activity. Involved in fatty acid metabolic process and response to superoxide. Localizes to mitochondrion. Is expressed in adipose tissue; heart; and skeletal muscle. Human ortholog(s) of this gene implicated in coronary restenosis; diabetic neuropathy; glucose metabolism disease (multiple); and obesity. Orthologous to human UCP3 (uncoupling protein 3); INTERACTS WITH (+)-dexrazoxane; 2,3,7,8-tetrachlorodibenzodioxine; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI645527; mitochondrial uncoupling protein 3; Slc2; Slc25a9; solute carrier family 25 member 9; UCP 3; UCP-; UCP-3; uncoupling protein 3, mitochondrial
Homo sapiens (human) : UCP3 (uncoupling protein 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ucp3 (uncoupling protein 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ucp3 (uncoupling protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : UCP3 (uncoupling protein 3)
Canis lupus familiaris (dog) : UCP3 (uncoupling protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ucp3 (uncoupling protein 3)
Sus scrofa (pig) : UCP3 (uncoupling protein 3)
Chlorocebus sabaeus (African green monkey) : UCP3 (uncoupling protein 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl7100,472,990 - 100,486,432 (+)EnsemblGRCm38mm10GRCm38
GRCm387100,472,991 - 100,486,432 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377107,621,500 - 107,634,941 (+)NCBIGRCm37mm9NCBIm37
MGSCv367100,347,073 - 100,360,514 (+)NCBImm8
Celera7100,810,580 - 100,824,026 (+)NCBICelera
Cytogenetic Map7E2NCBI
cM Map754.36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ucp3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11474
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.