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Gene: Ucp3 (uncoupling protein 3 (mitochondrial, proton carrier)) Mus musculus
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Symbol: Ucp3
Name: uncoupling protein 3 (mitochondrial, proton carrier)
RGD ID: 11474
Description: Exhibits oxidative phosphorylation uncoupler activity. Involved in fatty acid metabolic process and response to superoxide. Localizes to mitochondrion. Is expressed in adipose tissue; heart; and skeletal muscle. Human ortholog(s) of this gene implicated in coronary restenosis; diabetic neuropathy; glucose metabolism disease (multiple); and obesity. Orthologous to human UCP3 (uncoupling protein 3); INTERACTS WITH (+)-dexrazoxane; 2,3,7,8-tetrachlorodibenzodioxine; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI645527; mitochondrial uncoupling protein 3; Slc2; Slc25a9; solute carrier family 25 member 9; UCP 3; UCP-; UCP-3; uncoupling protein 3, mitochondrial
Orthologs:
Homo sapiens (human) : UCP3 (uncoupling protein 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ucp3 (uncoupling protein 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ucp3 (uncoupling protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : UCP3 (uncoupling protein 3)
Canis lupus familiaris (dog) : UCP3 (uncoupling protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ucp3 (uncoupling protein 3)
Sus scrofa (pig) : UCP3 (uncoupling protein 3)
Chlorocebus sabaeus (African green monkey) : UCP3 (uncoupling protein 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl7100,472,990 - 100,486,432 (+)EnsemblGRCm38mm10GRCm38
GRCm387100,472,991 - 100,486,432 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377107,621,500 - 107,634,941 (+)NCBIGRCm37mm9NCBIm37
MGSCv367100,347,073 - 100,360,514 (+)NCBImm8
Celera7100,810,580 - 100,824,026 (+)NCBICelera
Cytogenetic Map7E2NCBI
cM Map754.36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ucp3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11474
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.