Cyp2a4 (cytochrome P450, family 2, subfamily a, polypeptide 4) - Rat Genome Database

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Gene: Cyp2a4 (cytochrome P450, family 2, subfamily a, polypeptide 4) Mus musculus
Analyze
Symbol: Cyp2a4
Name: cytochrome P450, family 2, subfamily a, polypeptide 4
RGD ID: 1624100
MGI Page MGI
Description: Predicted to enable enzyme binding activity; heme binding activity; and monooxygenase activity. Involved in response to stilbenoid. Predicted to be located in cytoplasmic microtubule. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Is expressed in liver; lung; metanephros; nervous system; and nose. Orthologous to several human genes including CYP2A13 (cytochrome P450 family 2 subfamily A member 13) and CYP2A6 (cytochrome P450 family 2 subfamily A member 6).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI893559; Cyp15; Cyp15a1; CYPIIA4; cytochrome P450 2A4; cytochrome P450, 2a4; cytochrome P450-15-alpha; cytochrome P450-IIA3.1; D7Ucl; D7Ucla4; testosterone 15-alpha-hydroxylase; testosterone 15alpha-hydroxylase
RGD Orthologs
Human
Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Cyp2a21-ps  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39726,006,617 - 26,014,513 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl726,006,594 - 26,014,513 (+)EnsemblGRCm39 Ensembl
GRCm38726,307,192 - 26,315,088 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl726,307,169 - 26,315,088 (+)EnsemblGRCm38mm10GRCm38
MGSCv37727,092,211 - 27,100,107 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36726,015,952 - 26,023,848 (+)NCBIMGSCv36mm8
Celera720,896,679 - 20,902,855 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map714.39NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 9 of 9 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cyp2a4MouseCarpenter syndrome 2  ISORGD:13532738554872ClinVar Annotator: match by term: Carpenter syndrome 2ClinVarPMID:28492532
Cyp2a4Mousecongenital hypoplastic anemia  ISORGD:13532738554872ClinVar Annotator: match by term: Congenital hypoplastic anemiaClinVarPMID:28492532
Cyp2a4MouseCoumarin Sensitivity  ISORGD:13532738554872ClinVar Annotator: match by term: COUMARIN SENSITIVITYClinVarPMID:12325023
Cyp2a4Mousecraniosynostosis 1  ISORGD:13532738554872ClinVar Annotator: match by term: TWIST1-related craniosynostosisClinVarPMID:28492532
Cyp2a4MouseDiamond-Blackfan anemia  ISORGD:13532738554872ClinVar Annotator: match by term: Aase syndromeClinVarPMID:28492532
Cyp2a4MouseLynch syndrome  ISORGD:13532738554872ClinVar Annotator: match by term: APC-mutation negative familial colorectal cancerClinVarPMID:28306719
Cyp2a4Mousemaple syrup urine disease  ISORGD:13532738554872ClinVar Annotator: match by term: Maple syrup urine diseaseClinVarPMID:28492532
Cyp2a4Mousewarfarin resistance  ISORGD:13532738554872ClinVar Annotator: match by term: Coumarin resistanceClinVarPMID:12325023
Cyp2a4Mousewarfarin sensitivity  ISORGD:13532738554872ClinVar Annotator: match by term: Warfarin sensitivityClinVarPMID:12325023
1 to 9 of 9 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cyp2a4Mouseautism spectrum disorder  ISORGD:135327311554173CTD Direct Evidence: marker/mechanismCTDPMID:35663546
Cyp2a4MouseExperimental Liver Neoplasms  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:11420682

1 to 20 of 161 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cyp2a4Mouse(-)-anisomycin multiple interactionsEXP 64804641,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [[Anisomycin co-treated with NR1I3 protein] results in increased expression of CYP2A7 more ...CTDPMID:23539296
Cyp2a4Mouse(1->4)-beta-D-glucan multiple interactionsEXP 6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of CYP2A4 mRNACTDPMID:36331819
Cyp2a4Mouse(S)-nicotine increases expressionISORGD:24656480464Nicotine results in increased expression of CYP2A3 mRNACTDPMID:14972772|PMID:22934830
Cyp2a4Mouse1,2-dimethylhydrazine decreases expressionEXP 64804641,2-Dimethylhydrazine results in decreased expression of CYP2A4 mRNACTDPMID:22206623
Cyp2a4Mouse17beta-estradiol increases metabolic processingEXP 6480464CYP2A4 protein results in increased metabolism of EstradiolCTDPMID:10490589
Cyp2a4Mouse17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of CYP2A4 mRNACTDPMID:39298647
Cyp2a4Mouse17beta-estradiol affects expressionISORGD:24656480464Estradiol affects the expression of CYP2A3 mRNACTDPMID:32145629
Cyp2a4Mouse17beta-estradiol decreases expressionISORGD:13532736480464Estradiol results in decreased expression of CYP2A7 mRNACTDPMID:20106945
Cyp2a4Mouse1H-pyrazole increases expressionISORGD:24656480464pyrazole results in increased expression of CYP2A3 mRNACTDPMID:12845369
Cyp2a4Mouse2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsEXP 6480464[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased more ...CTDPMID:28433925
Cyp2a4Mouse2,2',4,4'-Tetrabromodiphenyl ether increases expressionISORGD:246564804642,2',4,4'-tetrabromodiphenyl ether results in increased expression of CYP2A3 mRNACTDPMID:31826744
Cyp2a4Mouse2,3,7,8-tetrachlorodibenzodioxine multiple interactionsEXP 6480464[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of CYP2A4 mRNA; [Tetrachlorodibenzodioxin co-treated more ...CTDPMID:16214954|PMID:28213091|PMID:28433925|PMID:34129049
Cyp2a4Mouse2,3,7,8-tetrachlorodibenzodioxine increases expressionISORGD:24656480464Tetrachlorodibenzodioxin results in increased expression of CYP2A3 mRNACTDPMID:21215274
Cyp2a4Mouse2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISORGD:13532736480464[Endosulfan co-treated with Tetrachlorodibenzodioxin] results in decreased expression of CYP2A7 mRNACTDPMID:26159488
Cyp2a4Mouse2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of CYP2A4 mRNACTDPMID:28213091
Cyp2a4Mouse2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of CYP2A4 mRNACTDPMID:28922406
Cyp2a4Mouse2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile decreases activityEXP 6480464Verapamil results in decreased activity of CYP2A4 proteinCTDPMID:18420780
Cyp2a4Mouse3-methylcholanthrene multiple interactionsISORGD:13532736480464Methylcholanthrene promotes the reaction [AHR protein binds to CYP2A7 promoter]CTDPMID:20348232
Cyp2a4Mouse3-methylcholanthrene increases expressionISORGD:24656480464Methylcholanthrene results in increased expression of CYP2A3 mRNACTDPMID:12845369|PMID:22934830
Cyp2a4Mouse3-methylcholanthrene increases expressionEXP 6480464Methylcholanthrene results in increased expression of CYP2A4 mRNACTDPMID:30503582

1 to 20 of 161 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cyp2a4Mousecoumarin metabolic process involved_inIBAPANTHER:PTN000670779|UniProtKB:P11509|RGD:24632290270 GO_CentralGO_REF:0000033
Cyp2a4Mouseepoxygenase P450 pathway involved_inIBAPANTHER:PTN002549507|RGD:6200882290270 GO_CentralGO_REF:0000033
Cyp2a4Mouseresponse to stilbenoid involved_inIEP 2290270 PMID:17086191UniProtPMID:17086191
Cyp2a4Mousexenobiotic metabolic process involved_inIBAPANTHER:PTN000670347|UniProtKB:P11509|UniProtKB:P33261|RGD:2467|UniProtKB:P10635|RGD:2466|UniProtKB:P10632|UniProtKB:P20813|RGD:2475|UniProtKB:Q8TAV3|RGD:619934|RGD:2476|RGD:620640|UniProtKB:P05181|UniProtKB:P117122290270 GO_CentralGO_REF:0000033

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cyp2a4Mousecytoplasm is_active_inIBAPANTHER:PTN000670347|UniProtKB:P11509|MGI:1929474|UniProtKB:Q96SQ9|UniProtKB:A0A087X1C5|MGI:88607|UniProtKB:P10635|WB:WBGene00000905|RGD:2466|RGD:2475|MGI:1270148|UniProtKB:Q8TAV3|RGD:2469|FB:FBgn0004959|MGI:1921769|RGD:6203702290270 GO_CentralGO_REF:0000033
Cyp2a4Mousecytoplasmic microtubule located_inISOUniProtKB:P115092290270 GO_CentralGO_REF:0000119
Cyp2a4Mouseendoplasmic reticulum membrane located_inIEAUniProtKB-SubCell:SL-00972290270 UniProtGO_REF:0000044

Molecular Function
1 to 10 of 10 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cyp2a4Mousearachidonate epoxygenase activity enablesIBAPANTHER:PTN002549507|RGD:6200882290270 GO_CentralGO_REF:0000033
Cyp2a4Mousecoumarin 7-hydroxylase activity enablesISOUniProtKB:P115092290270 GO_CentralGO_REF:0000119
Cyp2a4Mouseenzyme binding enablesISOUniProtKB:P115092290270 GO_CentralGO_REF:0000119
Cyp2a4Mouseheme binding enablesIBAPANTHER:PTN000670347|UniProtKB:P10635|UniProtKB:P05181|UniProtKB:P11509|UniProtKB:P20813|UniProtKB:Q6VVX0|UniProtKB:P33261|UniProtKB:Q166962290270 GO_CentralGO_REF:0000033
Cyp2a4Mouseheme binding enablesISOUniProtKB:P11509|UniProtKB:Q166962290270 GO_CentralGO_REF:0000119
Cyp2a4Mouseheme binding enablesIEAInterPro:IPR001128|InterPro:IPR002401|InterPro:IPR008067|InterPro:IPR0363962290270 InterProGO_REF:0000002
Cyp2a4Mouseiron ion binding enablesIEAInterPro:IPR001128|InterPro:IPR002401|InterPro:IPR008067|InterPro:IPR017972|InterPro:IPR0363962290270 InterProGO_REF:0000002
Cyp2a4Mouseoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen enablesIEAEC:1.14.14.12290270 UniProtGO_REF:0000003
Cyp2a4Mouseoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen enablesIBAPANTHER:PTN000670347|UniProtKB:P33261|UniProtKB:Q7Z449|UniProtKB:P05181|UniProtKB:P249032290270 GO_CentralGO_REF:0000033
Cyp2a4Mouseoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen enablesIEARHEA:171492290270 RHEAGO_REF:0000116
1 to 10 of 10 rows

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cyp2a4Mousephase I biotransformation pathway via cytochrome P450  ISORGD:24659068941 RGDPMID:12167220|REF_RGD_ID:1298847

Imported Annotations - SMPDB

1 to 11 of 11 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cyp2a4Mousecaffeine pharmacokinetics pathway  ISORGD:134342410402751 SMPDBSMP:00028
Cyp2a4Mousecyclophosphamide pharmacodynamics pathway  ISORGD:134342410402751 SMPDBSMP:00447
Cyp2a4Mousecyclophosphamide pharmacokinetics pathway  ISORGD:134342410402751 SMPDBSMP:00604
Cyp2a4Mouseifosfamide pharmacodynamics pathway  ISORGD:134342410402751 SMPDBSMP:00448
Cyp2a4Mouseifosfamide pharmacokinetics pathway  ISORGD:134342410402751 SMPDBSMP:00605
Cyp2a4Mousenicotine pharmacodynamics pathway  ISORGD:134342410402751 SMPDBSMP:00431
Cyp2a4Mousenicotine pharmacokinetics pathway  ISORGD:134342410402751 SMPDBSMP:00628
Cyp2a4Mouseparacetamol pharmacokinetics pathway   ISORGD:134342410402751 SMPDBSMP:00640
Cyp2a4Mouseretinol metabolic pathway   ISORGD:134342410402751 SMPDBSMP:00074
Cyp2a4Mousevalproic acid pharmacokinetics pathway  ISORGD:134342410402751 SMPDBSMP:00635
Cyp2a4Mousevitamin A deficiency pathway  ISORGD:134342410402751 SMPDBSMP:00336
1 to 11 of 11 rows

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cyp2a4Mouseretinol metabolic pathway   IEA 6907045 KEGGmmu:00830

#
Reference Title
Reference Citation
1. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:1417950   PMID:1970547   PMID:2415518   PMID:2703500   PMID:2733794   PMID:2765478   PMID:3346244   PMID:7565685   PMID:8188299   PMID:8250953   PMID:8297477   PMID:9408084  
PMID:9630227   PMID:10490589   PMID:12477932   PMID:12745259   PMID:14630516   PMID:14681479   PMID:17086191   PMID:21267068   PMID:21873635   PMID:22217847   PMID:24045421   PMID:27197076  
PMID:29968852   PMID:32987105   PMID:37838304  



Cyp2a4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39726,006,617 - 26,014,513 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl726,006,594 - 26,014,513 (+)EnsemblGRCm39 Ensembl
GRCm38726,307,192 - 26,315,088 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl726,307,169 - 26,315,088 (+)EnsemblGRCm38mm10GRCm38
MGSCv37727,092,211 - 27,100,107 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36726,015,952 - 26,023,848 (+)NCBIMGSCv36mm8
Celera720,896,679 - 20,902,855 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map714.39NCBI
CYP2A7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381940,875,439 - 40,882,231 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1940,875,439 - 40,882,752 (-)EnsemblGRCh38hg38GRCh38
GRCh371941,381,344 - 41,388,136 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361946,073,184 - 46,080,497 (-)NCBINCBI36Build 36hg18NCBI36
Build 341946,073,183 - 46,080,497NCBI
Celera1938,181,466 - 38,188,779 (-)NCBICelera
Cytogenetic Map19q13.2NCBI
HuRef1937,814,479 - 37,821,742 (-)NCBIHuRef
CHM1_11941,381,111 - 41,388,380 (-)NCBICHM1_1
T2T-CHM13v2.01943,696,148 - 43,702,882 (-)NCBIT2T-CHM13v2.0
Cyp2a3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8191,299,584 - 91,307,650 (+)NCBIGRCr8
mRatBN7.2182,171,914 - 82,179,980 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl182,169,949 - 82,179,979 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx187,588,938 - 87,597,006 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0196,075,221 - 96,083,279 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0189,344,793 - 89,352,861 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0183,653,248 - 83,662,118 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl183,653,234 - 83,766,484 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0184,869,280 - 84,876,600 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4181,944,896 - 81,953,007 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1182,023,006 - 82,030,923 (+)NCBI
Celera176,591,113 - 76,599,123 (+)NCBICelera
Cytogenetic Map1q21NCBI

.

.
Variants in Cyp2a4
447 total Variants

Predicted Target Of
Summary Value
Count of predictions:69
Count of miRNA genes:67
Interacting mature miRNAs:68
Transcripts:ENSMUST00000098657
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 21 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1303248547032621Mouse
1301041Prnr2_mprion resistance 2 (mouse)Not determined71872879439674033Mouse
12904742Litsq2_mlitter size QTL 2 (mouse)72267388756674033Mouse
1301622Eae12_msusceptibility to experimental allergic encephalomyelitis 12 (mouse)Not determined71928001553280104Mouse
11354952Pdcc1_mplasmacytoid dentritic cell compartment 1 (mouse)72306653157066531Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
25314314Sccor1_msynaptonemal complex length to mean MLH1 count ratio 1 (mouse)71333392547349748Mouse
10449139Eosn1_meosinophil differential 1 (mouse)71248087746480877Mouse

1 to 10 of 21 rows
AI893559  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7A3UniSTS
cM Map76.5UniSTS
cM Map76.5UniSTS
Whitehead/MRC_RH7347.01UniSTS
D17973  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38726,843,095 - 26,843,205UniSTSGRCm38
MGSCv37727,628,114 - 27,628,224UniSTSGRCm37
Celera721,423,796 - 21,423,906UniSTS
Cytogenetic Map7A3UniSTS
cM Map76.5UniSTS
cM Map76.5UniSTS
Whitehead_YAC7 UniSTS
J03549  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38726,952,382 - 26,952,488UniSTSGRCm38
GRCm38726,314,919 - 26,315,025UniSTSGRCm38
MGSCv37727,737,401 - 27,737,507UniSTSGRCm37
MGSCv37727,099,938 - 27,100,044UniSTSGRCm37
Celera720,902,686 - 20,902,792UniSTS
Celera721,523,846 - 21,523,952UniSTS
Cytogenetic Map7A3UniSTS
cM Map76.5UniSTS
Whitehead/MRC_RH7331.37UniSTS
Cyp2a4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7A3UniSTS
cM Map76.5UniSTS







Ensembl Acc Id: ENSMUST00000098657   ⟹   ENSMUSP00000096254
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl726,006,594 - 26,014,513 (+)Ensembl
GRCm38.p6 Ensembl726,307,169 - 26,315,088 (+)Ensembl
RefSeq Acc Id: NM_009997   ⟹   NP_034127
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39726,006,617 - 26,014,513 (+)NCBI
GRCm38726,307,192 - 26,315,088 (+)ENTREZGENE
MGSCv37727,092,211 - 27,100,107 (+)RGD
Celera720,896,679 - 20,902,855 (+)RGD
cM Map7 ENTREZGENE
Sequence:
Protein RefSeqs NP_034127 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA37797 (Get FASTA)   NCBI Sequence Viewer  
  AAH10761 (Get FASTA)   NCBI Sequence Viewer  
  AAH11233 (Get FASTA)   NCBI Sequence Viewer  
  AAH63778 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000096254
  ENSMUSP00000096254.4
GenBank Protein P15392 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_034127   ⟸   NM_009997
- UniProtKB: P20852 (UniProtKB/Swiss-Prot),   Q91XG2 (UniProtKB/Swiss-Prot),   P15392 (UniProtKB/Swiss-Prot),   Q80XK1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000096254   ⟸   ENSMUST00000098657

Name Modeler Protein Id AA Range Protein Structure
AF-P15392-F1-model_v2 AlphaFold P15392 1-494 view protein structure

RGD ID:6892318
Promoter ID:EPDNEW_M9610
Type:single initiation site
Name:Cyp2a4_1
Description:Mus musculus cytochrome P450, family 2, subfamily a, polypeptide4 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38726,307,193 - 26,307,253EPDNEW
RGD ID:6840902
Promoter ID:MM_KWN:49493
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:NM_009997
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36727,092,111 - 27,092,611 (+)MPROMDB


1 to 28 of 28 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000074254 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000098657 ENTREZGENE
  ENSMUST00000098657.5 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.630.10 UniProtKB/Swiss-Prot
InterPro Cyt_P450 UniProtKB/Swiss-Prot
  Cyt_P450_CS UniProtKB/Swiss-Prot
  Cyt_P450_E_grp-I UniProtKB/Swiss-Prot
  Cyt_P450_E_grp-I_CYP2A-like UniProtKB/Swiss-Prot
  Cyt_P450_sf UniProtKB/Swiss-Prot
  Cytochrome_P450_fam2 UniProtKB/Swiss-Prot
KEGG Report mmu:13086 UniProtKB/Swiss-Prot
MGD MGI:88596 ENTREZGENE
NCBI Gene 13086 ENTREZGENE
PANTHER CYTOCHROME P450 2A6 UniProtKB/Swiss-Prot
  CYTOCHROME P450 508A4-RELATED UniProtKB/Swiss-Prot
Pfam p450 UniProtKB/Swiss-Prot
PharmGKB CYP2A7 RGD
PhenoGen Cyp2a4 PhenoGen
PRINTS EP450I UniProtKB/Swiss-Prot
  EP450ICYP2A UniProtKB/Swiss-Prot
  P450 UniProtKB/Swiss-Prot
PROSITE CYTOCHROME_P450 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48264 UniProtKB/Swiss-Prot
UniProt CP2A4_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  P20852 ENTREZGENE
  Q80XK1 ENTREZGENE
  Q91XG2 ENTREZGENE
UniProt Secondary Q91XG2 UniProtKB/Swiss-Prot
1 to 28 of 28 rows