Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-catechin | multiple interactions | ISO | RNF14 (Homo sapiens) | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of RNF14 mRNA | CTD | PMID:24763279 | (+)-schisandrin B | multiple interactions | ISO | Rnf14 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of RNF14 mRNA] | CTD | PMID:31150632 | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of RNF14 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RNF14 mRNA | CTD | PMID:22206623 | 17beta-estradiol | affects expression | ISO | RNF14 (Homo sapiens) | 6480464 | Estradiol affects the expression of RNF14 mRNA | CTD | PMID:14699072 | 17beta-estradiol | multiple interactions | ISO | RNF14 (Homo sapiens) | 6480464 | [Estradiol binds to ESR2 protein] which results in increased expression of RNF14 mRNA | CTD | PMID:20404318 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of RNF14 mRNA | CTD | PMID:20702594 and PMID:21570461 | 2,3,7,8-Tetrachlorodibenzofuran | affects expression | EXP | | 6480464 | 2 more ... | CTD | PMID:20702594 | 2,4-dinitrotoluene | affects expression | ISO | Rnf14 (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of RNF14 mRNA | CTD | PMID:21346803 | 2-methylcholine | affects expression | ISO | RNF14 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of RNF14 mRNA | CTD | PMID:21179406 | 3-chloropropane-1,2-diol | increases expression | ISO | Rnf14 (Rattus norvegicus) | 6480464 | alpha-Chlorohydrin results in increased expression of RNF14 protein | CTD | PMID:34915118 | 4,4'-sulfonyldiphenol | increases expression | ISO | RNF14 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of RNF14 protein | CTD | PMID:34186270 | 5-aza-2'-deoxycytidine | affects expression | ISO | RNF14 (Homo sapiens) | 6480464 | Decitabine affects the expression of RNF14 mRNA | CTD | PMID:23300844 | 6-propyl-2-thiouracil | decreases expression | ISO | Rnf14 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of RNF14 mRNA | CTD | PMID:30047161 | acrylamide | decreases expression | ISO | Rnf14 (Rattus norvegicus) | 6480464 | Acrylamide results in decreased expression of RNF14 mRNA | CTD | PMID:28959563 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of RNF14 mRNA | CTD | PMID:19770486 | amitrole | decreases expression | ISO | Rnf14 (Rattus norvegicus) | 6480464 | Amitrole results in decreased expression of RNF14 mRNA | CTD | PMID:30047161 | aristolochic acid A | increases expression | ISO | RNF14 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of RNF14 mRNA and aristolochic acid I results in increased expression of RNF14 protein | CTD | PMID:33212167 | Aroclor 1254 | decreases expression | EXP | | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of RNF14 mRNA | CTD | PMID:23650126 | arsane | decreases expression | EXP | | 6480464 | Arsenic results in decreased expression of RNF14 mRNA | CTD | PMID:19654921 | arsenic atom | decreases expression | EXP | | 6480464 | Arsenic results in decreased expression of RNF14 mRNA | CTD | PMID:19654921 | arsenite(3-) | multiple interactions | ISO | RNF14 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to RNF14 mRNA] | CTD | PMID:32406909 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of RNF14 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | affects methylation | ISO | RNF14 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of RNF14 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | ISO | RNF14 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of RNF14 promoter | CTD | PMID:27901495 | bis(2-ethylhexyl) phthalate | increases expression | EXP | | 6480464 | Diethylhexyl Phthalate results in increased expression of RNF14 mRNA | CTD | PMID:21318169 | bisphenol A | increases expression | ISO | Rnf14 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of RNF14 mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | ISO | RNF14 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of RNF14 protein | CTD | PMID:34186270 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of RNF14 mRNA | CTD | PMID:33221593 | bisphenol A | decreases expression | ISO | Rnf14 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of RNF14 mRNA | CTD | PMID:30816183 and PMID:34947998 | bortezomib | increases expression | ISO | RNF14 (Homo sapiens) | 6480464 | Bortezomib results in increased expression of RNF14 mRNA | CTD | PMID:20977926 | CGP 52608 | multiple interactions | ISO | RNF14 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to RNF14 gene] | CTD | PMID:28238834 | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of RNF14 mRNA | CTD | PMID:37019170 | chromium(6+) | decreases expression | ISO | Rnf14 (Rattus norvegicus) | 6480464 | chromium hexavalent ion results in decreased expression of RNF14 protein | CTD | PMID:32679048 | cisplatin | affects expression | ISO | RNF14 (Homo sapiens) | 6480464 | Cisplatin affects the expression of RNF14 mRNA | CTD | PMID:23300844 | cobalt dichloride | increases expression | ISO | RNF14 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of RNF14 mRNA | CTD | PMID:19376846 | cocaine | increases expression | ISO | Rnf14 (Rattus norvegicus) | 6480464 | Cocaine results in increased expression of RNF14 protein | CTD | PMID:25100957 | crocidolite asbestos | affects expression | ISO | RNF14 (Homo sapiens) | 6480464 | Asbestos and Crocidolite affects the expression of RNF14 mRNA | CTD | PMID:17331233 | cyclosporin A | increases expression | ISO | RNF14 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of RNF14 mRNA | CTD | PMID:25562108 | cylindrospermopsin | increases expression | ISO | RNF14 (Homo sapiens) | 6480464 | cylindrospermopsin results in increased expression of RNF14 mRNA | CTD | PMID:24921660 | diethyl maleate | increases expression | EXP | | 6480464 | diethyl maleate results in increased expression of RNF14 mRNA | CTD | PMID:25270620 | dioxygen | increases expression | EXP | | 6480464 | Oxygen deficiency results in increased expression of RNF14 mRNA | CTD | PMID:22629407 | dioxygen | multiple interactions | EXP | | 6480464 | Oxygen inhibits the reaction [Oxygen deficiency results in increased expression of RNF14 mRNA] | CTD | PMID:22629407 | enzyme inhibitor | multiple interactions | ISO | RNF14 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of RNF14 protein | CTD | PMID:23301498 | ethanol | affects splicing | EXP | | 6480464 | Ethanol affects the splicing of RNF14 mRNA | CTD | PMID:30319688 | ethyl methanesulfonate | increases expression | ISO | RNF14 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of RNF14 mRNA | CTD | PMID:23649840 | fenofibrate | increases expression | EXP | | 6480464 | Fenofibrate results in increased expression of RNF14 mRNA | CTD | PMID:21318169 | fenofibrate | multiple interactions | EXP | | 6480464 | PPARA protein affects the reaction [Fenofibrate results in increased expression of RNF14 mRNA] | CTD | PMID:21318169 | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RNF14 mRNA | CTD | PMID:22206623 | FR900359 | increases phosphorylation | ISO | RNF14 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of RNF14 protein | CTD | PMID:37730182 | methimazole | decreases expression | ISO | Rnf14 (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of RNF14 mRNA | CTD | PMID:30047161 | methyl methanesulfonate | increases expression | ISO | RNF14 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of RNF14 mRNA | CTD | PMID:23649840 | methylmercury chloride | decreases expression | ISO | RNF14 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of RNF14 mRNA | CTD | PMID:28001369 | nefazodone | increases expression | ISO | Rnf14 (Rattus norvegicus) | 6480464 | nefazodone results in increased expression of RNF14 mRNA | CTD | PMID:24136188 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of RNF14 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | Rnf14 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of RNF14 mRNA | CTD | PMID:33387578 | paracetamol | decreases expression | ISO | RNF14 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of RNF14 mRNA | CTD | PMID:21420995 | phenobarbital | affects expression | EXP | | 6480464 | Phenobarbital affects the expression of RNF14 mRNA | CTD | PMID:23091169 | quercetin | decreases expression | ISO | RNF14 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of RNF14 mRNA | CTD | PMID:21632981 | quercitrin | decreases expression | ISO | RNF14 (Homo sapiens) | 6480464 | quercitrin results in decreased expression of RNF14 mRNA | CTD | PMID:25193878 | sulfadimethoxine | decreases expression | ISO | Rnf14 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in decreased expression of RNF14 mRNA | CTD | PMID:30047161 | testosterone | decreases expression | EXP | | 6480464 | Testosterone results in decreased expression of RNF14 mRNA | CTD | PMID:21669218 | tetrachloromethane | decreases expression | ISO | Rnf14 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of RNF14 mRNA | CTD | PMID:31150632 | tetrachloromethane | multiple interactions | ISO | Rnf14 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of RNF14 mRNA] | CTD | PMID:31150632 | thioacetamide | decreases expression | ISO | Rnf14 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of RNF14 mRNA | CTD | PMID:34492290 | trichloroethene | increases expression | ISO | Rnf14 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of RNF14 mRNA | CTD | PMID:33387578 | trichostatin A | affects expression | ISO | RNF14 (Homo sapiens) | 6480464 | trichostatin A affects the expression of RNF14 mRNA | CTD | PMID:28542535 | triphenyl phosphate | increases expression | ISO | Rnf14 (Rattus norvegicus) | 6480464 | triphenyl phosphate results in increased expression of RNF14 mRNA | CTD | PMID:30589522 | triptonide | increases expression | EXP | | 6480464 | triptonide results in increased expression of RNF14 mRNA | CTD | PMID:33045310 | urethane | increases expression | ISO | RNF14 (Homo sapiens) | 6480464 | Urethane results in increased expression of RNF14 mRNA | CTD | PMID:28818685 | valproic acid | affects expression | ISO | RNF14 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of RNF14 mRNA | CTD | PMID:25979313 | vinclozolin | increases methylation | ISO | Rnf14 (Rattus norvegicus) | 6480464 | vinclozolin results in increased methylation of RNF14 gene | CTD | PMID:31682807 | |