(S)-nicotine increases expression EXP 6480464 Nicotine results in increased expression of ALOX12 mRNA CTD PMID:16254210 1,2-dimethylhydrazine increases expression EXP 6480464 1 and 2-Dimethylhydrazine results in increased expression of ALOX12 mRNA CTD PMID:22206623 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of ALOX12 mRNA CTD PMID:17942748 17alpha-ethynylestradiol affects expression EXP 6480464 Ethinyl Estradiol affects the expression of ALOX12 mRNA CTD PMID:17555576 17alpha-ethynylestradiol multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ALOX12 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ALOX12 mRNA and [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of ALOX12 mRNA CTD PMID:17942748 and PMID:25975270 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Alox12 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of ALOX12 mRNA CTD PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of ALOX12 mRNA CTD PMID:26377647 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine increases expression ISO ALOX12 (Homo sapiens) 6480464 Platelet Activating Factor results in increased expression of ALOX12 mRNA CTD PMID:16386258 2-hydroxypropanoic acid decreases expression ISO ALOX12 (Homo sapiens) 6480464 Lactic Acid results in decreased expression of ALOX12 mRNA CTD PMID:30851411 3,4-methylenedioxymethamphetamine increases expression EXP 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of ALOX12 mRNA CTD PMID:26251327 3,4-methylenedioxymethamphetamine increases methylation EXP 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in increased methylation of ALOX12 promoter CTD PMID:26251327 4-hydroxyphenyl retinamide increases expression EXP 6480464 Fenretinide results in increased expression of ALOX12 mRNA CTD PMID:28973697 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of ALOX12 mRNA CTD PMID:30807115 aflatoxin B1 increases methylation ISO ALOX12 (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of ALOX12 intron CTD PMID:30157460 Aflatoxin B2 alpha increases methylation ISO ALOX12 (Homo sapiens) 6480464 aflatoxin B2 results in increased methylation of ALOX12 intron CTD PMID:30157460 aldehydo-D-glucose increases expression ISO ALOX12 (Homo sapiens) 6480464 Glucose results in increased expression of ALOX12 mRNA CTD PMID:32942007 arachidonic acid affects response to substance EXP 6480464 ALOX12 protein affects the susceptibility to Arachidonic Acid CTD PMID:19373248 arachidonic acid increases metabolic processing ISO ALOX12 (Homo sapiens) 6480464 ALOX12 protein results in increased metabolism of Arachidonic Acid CTD PMID:17027136 aristolochic acid A increases expression ISO ALOX12 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of ALOX12 mRNA CTD PMID:33212167 baicalein multiple interactions ISO ALOX12 (Homo sapiens) 6480464 baicalein inhibits the reaction [ALOX12 protein results in increased chemical synthesis of 12-Hydroxy-5 more ... CTD PMID:17027136 baicalein decreases activity ISO ALOX12 (Homo sapiens) 6480464 baicalein results in decreased activity of ALOX12 protein CTD PMID:17027136 and PMID:23238474 benoxaprofen decreases activity ISO Alox12 (Rattus norvegicus) 6480464 benoxaprofen results in decreased activity of ALOX12 protein CTD PMID:3928952 benzene decreases expression ISO ALOX12 (Homo sapiens) 6480464 Benzene results in decreased expression of ALOX12 mRNA CTD PMID:19162166 benzo[a]pyrene affects methylation ISO ALOX12 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of ALOX12 intron CTD PMID:30157460 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of ALOX12 mRNA CTD PMID:32417428 bifenthrin decreases expression EXP 6480464 bifenthrin results in decreased expression of ALOX12 mRNA CTD PMID:26071804 bis(2-chloroethyl) sulfide increases expression EXP 6480464 Mustard Gas results in increased expression of ALOX12 mRNA CTD PMID:15674844 bisphenol A decreases expression ISO Alox12 (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of ALOX12 mRNA CTD PMID:26141625 and PMID:30816183 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of ALOX12 mRNA and bisphenol A results in decreased expression of ALOX12 protein CTD PMID:26063408 and PMID:35999755 bisphenol F decreases expression ISO Alox12 (Rattus norvegicus) 6480464 4 and 4'-bisphenol F results in decreased expression of ALOX12 mRNA CTD PMID:26186136 bisphenol F increases expression EXP 6480464 bisphenol F results in increased expression of ALOX12 mRNA CTD PMID:30951980 bortezomib increases response to substance ISO ALOX12 (Homo sapiens) 6480464 ALOX12 gene SNP results in increased susceptibility to Bortezomib CTD PMID:20864405 calcitriol decreases expression ISO ALOX12 (Homo sapiens) 6480464 Calcitriol results in decreased expression of ALOX12 mRNA CTD PMID:16002434 carbon nanotube decreases expression EXP 6480464 Nanotubes more ... CTD PMID:25554681 carmustine affects response to substance EXP 6480464 ALOX12 protein affects the susceptibility to Carmustine CTD PMID:19373248 carmustine decreases expression ISO Alox12 (Rattus norvegicus) 6480464 Carmustine results in decreased expression of ALOX12 mRNA CTD PMID:16005536 cerium trichloride decreases expression ISO ALOX12 (Homo sapiens) 6480464 cerous chloride results in decreased expression of ALOX12 mRNA CTD PMID:28954213 cerium trichloride multiple interactions ISO ALOX12 (Homo sapiens) 6480464 [cerous chloride co-treated with lanthanum chloride] results in decreased expression of ALOX12 mRNA CTD PMID:28954213 CGP 52608 multiple interactions ISO ALOX12 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to ALOX12 gene] CTD PMID:28238834 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of ALOX12 mRNA CTD PMID:15464296 copper atom increases expression ISO Alox12 (Rattus norvegicus) 6480464 Copper results in increased expression of ALOX12 mRNA CTD PMID:30556269 copper(0) increases expression ISO Alox12 (Rattus norvegicus) 6480464 Copper results in increased expression of ALOX12 mRNA CTD PMID:30556269 D-glucose increases expression ISO ALOX12 (Homo sapiens) 6480464 Glucose results in increased expression of ALOX12 mRNA CTD PMID:32942007 D-penicillamine increases expression ISO Alox12 (Rattus norvegicus) 6480464 Penicillamine results in increased expression of ALOX12 mRNA CTD PMID:19575532 D-penicillamine decreases expression ISO Alox12 (Rattus norvegicus) 6480464 Penicillamine results in decreased expression of ALOX12 mRNA CTD PMID:19575532 dextran sulfate decreases expression EXP 6480464 Dextran Sulfate results in decreased expression of ALOX12 protein CTD PMID:35999755 dioxygen increases expression ISO ALOX12 (Homo sapiens) 6480464 Oxygen deficiency results in increased expression of ALOX12 mRNA CTD PMID:35883890 dithiol decreases activity ISO Alox12 (Rattus norvegicus) 6480464 dithiol results in decreased activity of ALOX12 protein CTD PMID:3928952 diuron decreases expression ISO Alox12 (Rattus norvegicus) 6480464 Diuron results in decreased expression of ALOX12 mRNA CTD PMID:21551480 docebenone decreases activity EXP 6480464 2 more ... CTD PMID:23238474 fenofibrate increases expression ISO ALOX12 (Homo sapiens) 6480464 Fenofibrate results in increased expression of ALOX12 mRNA CTD PMID:12759900 flavonoids decreases expression ISO Alox12 (Rattus norvegicus) 6480464 Flavonoids results in decreased expression of ALOX12 mRNA CTD PMID:18035473 genistein decreases expression EXP 6480464 Genistein results in decreased expression of ALOX12 mRNA CTD PMID:22553218 glucose increases expression ISO ALOX12 (Homo sapiens) 6480464 Glucose results in increased expression of ALOX12 mRNA CTD PMID:32942007 glutathione disulfide affects response to substance EXP 6480464 ALOX12 protein affects the susceptibility to Glutathione Disulfide CTD PMID:19373248 glutathione disulfide increases glutathionylation EXP 6480464 Glutathione Disulfide results in increased glutathionylation of ALOX12 protein CTD PMID:19373248 glutathione disulfide increases activity EXP 6480464 Glutathione Disulfide results in increased activity of ALOX12 protein CTD PMID:19373248 hydroquinone increases expression ISO ALOX12 (Homo sapiens) 6480464 hydroquinone results in increased expression of ALOX12 mRNA CTD PMID:31256213 indometacin decreases activity ISO Alox12 (Rattus norvegicus) 6480464 Indomethacin results in decreased activity of ALOX12 protein CTD PMID:3928952 kaempferol decreases activity ISO ALOX12 (Homo sapiens) 6480464 kaempferol results in decreased activity of ALOX12 protein CTD PMID:17027136 kaempferol multiple interactions ISO ALOX12 (Homo sapiens) 6480464 kaempferol inhibits the reaction [ALOX12 protein results in increased chemical synthesis of 12-Hydroxy-5 more ... CTD PMID:17027136 Licochalcone B increases expression ISO ALOX12 (Homo sapiens) 6480464 licochalcone B results in increased expression of ALOX12 mRNA CTD PMID:33647349 lidocaine increases expression ISO Alox12 (Rattus norvegicus) 6480464 Lidocaine results in increased expression of ALOX12 mRNA CTD PMID:35283115 masoprocol multiple interactions ISO ALOX12 (Homo sapiens) 6480464 Masoprocol inhibits the reaction [ALOX12 protein results in increased chemical synthesis of 12-Hydroxy-5 more ... CTD PMID:17027136 masoprocol decreases activity ISO Alox12 (Rattus norvegicus) 6480464 Masoprocol results in decreased activity of ALOX12 protein CTD PMID:3928952 and PMID:9258337 masoprocol decreases activity ISO ALOX12 (Homo sapiens) 6480464 Masoprocol results in decreased activity of ALOX12 protein CTD PMID:17027136 more ... methotrexate decreases expression ISO Alox12 (Rattus norvegicus) 6480464 Methotrexate results in decreased expression of ALOX12 mRNA CTD PMID:16005536 methotrexate decreases expression ISO ALOX12 (Homo sapiens) 6480464 Methotrexate results in decreased expression of ALOX12 mRNA CTD PMID:17400583 nickel atom decreases expression ISO ALOX12 (Homo sapiens) 6480464 Nickel results in decreased expression of ALOX12 mRNA CTD PMID:24768652 nicotine increases expression EXP 6480464 Nicotine results in increased expression of ALOX12 mRNA CTD PMID:16254210 oxaliplatin multiple interactions ISO Alox12 (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of ALOX12 mRNA CTD PMID:25729387 ozone multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of ALOX12 mRNA CTD PMID:34911549 perfluorohexanesulfonic acid increases expression EXP 6480464 perfluorohexanesulfonic acid results in increased expression of ALOX12 mRNA CTD PMID:37995155 picrotoxin increases expression ISO Alox12 (Rattus norvegicus) 6480464 Picrotoxin results in increased expression of ALOX12 mRNA CTD PMID:15170462 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of ALOX12 mRNA CTD PMID:20813756 polymyxin B2 increases expression ISO ALOX12 (Homo sapiens) 6480464 Polymyxin B results in increased expression of ALOX12 protein CTD PMID:37088170 polymyxin B2 multiple interactions ISO ALOX12 (Homo sapiens) 6480464 TP53 protein promotes the reaction [Polymyxin B results in increased expression of ALOX12 protein] CTD PMID:37088170 quercetin decreases activity ISO ALOX12 (Homo sapiens) 6480464 Quercetin results in decreased activity of ALOX12 protein CTD PMID:17027136 quercetin multiple interactions ISO ALOX12 (Homo sapiens) 6480464 Quercetin inhibits the reaction [ALOX12 protein results in increased chemical synthesis of 12-Hydroxy-5 more ... CTD PMID:17027136 rac-lactic acid decreases expression ISO ALOX12 (Homo sapiens) 6480464 Lactic Acid results in decreased expression of ALOX12 mRNA CTD PMID:30851411 resveratrol decreases activity ISO ALOX12 (Homo sapiens) 6480464 resveratrol results in decreased activity of ALOX12 protein CTD PMID:17027136 resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of ALOX12 protein CTD PMID:25116358 resveratrol multiple interactions ISO ALOX12 (Homo sapiens) 6480464 resveratrol inhibits the reaction [ALOX12 protein results in increased chemical synthesis of 12-Hydroxy-5 more ... CTD PMID:17027136 sodium arsenite multiple interactions ISO ALOX12 (Homo sapiens) 6480464 [CARM1 mutant form co-treated with sodium arsenite] results in increased expression of ALOX12 mRNA and [PRMT1 mutant form co-treated with sodium arsenite] results in increased expression of ALOX12 mRNA CTD PMID:23699174 sodium arsenite increases expression ISO ALOX12 (Homo sapiens) 6480464 sodium arsenite results in increased expression of ALOX12 mRNA CTD PMID:28229933 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of ALOX12 mRNA CTD PMID:25065748 and PMID:31170414 Soman increases expression ISO Alox12 (Rattus norvegicus) 6480464 Soman results in increased expression of ALOX12 mRNA CTD PMID:19281266 tamoxifen affects expression EXP 6480464 Tamoxifen affects the expression of ALOX12 mRNA CTD PMID:17555576 tetraphene increases expression EXP 6480464 benz(a)anthracene results in increased expression of ALOX12 mRNA CTD PMID:26377693 tioguanine decreases expression ISO Alox12 (Rattus norvegicus) 6480464 Thioguanine results in decreased expression of ALOX12 mRNA CTD PMID:16005536 titanium dioxide decreases expression EXP 6480464 titanium dioxide results in decreased expression of ALOX12 mRNA CTD PMID:23557971 and PMID:29264374 topotecan multiple interactions ISO Alox12 (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of ALOX12 mRNA CTD PMID:25729387 trichloroethene decreases expression ISO Alox12 (Rattus norvegicus) 6480464 Trichloroethylene results in decreased expression of ALOX12 mRNA CTD PMID:33387578 trimellitic anhydride decreases expression EXP 6480464 trimellitic anhydride results in decreased expression of ALOX12 mRNA CTD PMID:19042947 triptonide increases expression EXP 6480464 triptonide results in increased expression of ALOX12 mRNA CTD PMID:33045310 valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of ALOX12 mRNA CTD PMID:17963808 valproic acid increases expression ISO Alox12 (Rattus norvegicus) 6480464 Valproic Acid results in increased expression of ALOX12 mRNA CTD PMID:35594946