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Gene: Mat2a (methionine adenosyltransferase II, alpha) Mus musculus
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Symbol: Mat2a
Name: methionine adenosyltransferase II, alpha
Description: Exhibits methionine adenosyltransferase activity. Involved in S-adenosylmethionine biosynthetic process and cellular response to leukemia inhibitory factor. Predicted to localize to cytosol and methionine adenosyltransferase complex. Is expressed in eye; gut; male reproductive gland or organ; metanephros; and nervous system. Orthologous to human MAT2A (methionine adenosyltransferase 2A); PARTICIPATES IN choline metabolic pathway; glycine N-methyltransferase deficiency pathway; homocystinuria pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,5-diethoxycarbonyl-1,4-dihydrocollidine; 7,12-dimethyltetraphene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: adoMet synthase 2; adoMet synthetase 2; D630045P18Rik; MAT 2; methionine adenosyltransferase 2; MGC6545; S-adenosylmethionine synthase isoform type-2; S-adenosylmethionine synthetase isoform type-2
Orthologs:
Homo sapiens (human) : MAT2A (methionine adenosyltransferase 2A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mat2a (methionine adenosyltransferase 2A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mat2a (methionine adenosyltransferase 2A)
Pan paniscus (bonobo/pygmy chimpanzee) : MAT2A (methionine adenosyltransferase 2A)
Canis lupus familiaris (dog) : MAT2A (methionine adenosyltransferase 2A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mat2a (methionine adenosyltransferase 2A)
Sus scrofa (pig) : MAT2A (methionine adenosyltransferase 2A)
Chlorocebus sabaeus (African green monkey) : MAT2A (methionine adenosyltransferase 2A)
Heterocephalus glaber (naked mole-rat) : Mat2a (methionine adenosyltransferase 2A)
more info ...
Related Pseudogenes: Gm9523  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl672,432,799 - 72,439,558 (-)EnsemblGRCm38mm10GRCm38
GRCm38672,432,796 - 72,439,556 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37672,382,793 - 72,389,552 (-)NCBIGRCm37mm9NCBIm37
MGSCv36672,362,308 - 72,369,067 (-)NCBImm8
Celera674,527,849 - 74,534,608 (-)NCBICelera
Cytogenetic Map6C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Mat2a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732781
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.