Gde1 (glycerophosphodiester phosphodiesterase 1)

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Gene: Gde1 (glycerophosphodiester phosphodiesterase 1) Mus musculus

Analyze

Symbol:

Gde1

Name:

glycerophosphodiester phosphodiesterase 1

RGD ID:

737531

MGI Page

MGI

Description:

Enables glycerophosphodiester phosphodiesterase activity; glycerophosphoinositol glycerophosphodiesterase activity; and lysophospholipase activity. Involved in ethanolamine metabolic process. Acts upstream of or within N-acylethanolamine metabolic process and phospholipid metabolic process. Located in plasma membrane. Is expressed in several structures, including ganglia; gut; lower urinary tract; lung; and nasal cavity epithelium. Orthologous to human GDE1 (glycerophosphodiester phosphodiesterase 1).

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

1200003M13Rik; glycerophosphoinositol glycerophosphodiesterase GDE1; lysophospholipase D GDE1; membrane interacting protein of RGS16; membrane-interacting protein of RGS16; MIR; Mir16; RGS16

RGD Orthologs

Human

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GDE1 (glycerophosphodiester phosphodiesterase 1)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Gde1 (glycerophosphodiester phosphodiesterase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gde1 (glycerophosphodiester phosphodiesterase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GDE1 (glycerophosphodiester phosphodiesterase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GDE1 (glycerophosphodiester phosphodiesterase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gde1 (glycerophosphodiester phosphodiesterase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GDE1 (glycerophosphodiester phosphodiesterase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GDE1 (glycerophosphodiester phosphodiesterase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gde1 (glycerophosphodiester phosphodiesterase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Gde1 (glycerophosphodiester phosphodiesterase 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	GDE1 (glycerophosphodiester phosphodiesterase 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gde1 (glycerophosphodiester phosphodiesterase 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Drosophila melanogaster (fruit fly):	CG14883	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	T09B9.3	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	T12B3.3	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	T22G5.1	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	ZC155.4	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	118,287,781 - 118,304,961 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	118,287,768 - 118,305,001 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	118,688,558 - 118,705,738 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	118,688,545 - 118,705,778 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	125,832,072 - 125,849,252 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	118,479,707 - 118,496,887 (-)	NCBI		MGSCv36	mm8
Celera	7	118,620,760 - 118,637,260 (-)	NCBI		Celera
Cytogenetic Map	7	F2	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(2,4,5-trichlorophenoxy)acetic acid (EXP)

1,2-dimethylhydrazine (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-butoxyethanol (EXP)

2-hydroxypropanoic acid (ISO)

3H-1,2-dithiole-3-thione (ISO)

acetamide (ISO)

acrolein (ISO)

aldrin (EXP)

alpha-pinene (ISO)

arsenous acid (ISO)

benzo[a]pyrene (EXP)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-ethylhexyl) phthalate (EXP)

bisphenol A (ISO)

buspirone (ISO)

cadmium dichloride (ISO)

carbon nanotube (EXP)

chlordecone (EXP)

chloroethene (EXP)

chromium(6+) (EXP)

cisplatin (ISO)

clofibrate (ISO)

copper(II) sulfate (EXP,ISO)

cyclosporin A (ISO)

decabromodiphenyl ether (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (ISO)

diuron (ISO)

endosulfan (ISO)

epoxiconazole (EXP)

fenofibrate (ISO)

fulvestrant (ISO)

leflunomide (ISO)

methidathion (EXP)

methyl methanesulfonate (ISO)

nefazodone (ISO)

nickel dichloride (ISO)

nimesulide (ISO)

ozone (ISO)

paraquat (ISO)

parathion (EXP)

perfluorooctanoic acid (ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

rac-lactic acid (ISO)

tetrachloromethane (EXP)

tetracycline (EXP)

thapsigargin (ISO)

thioacetamide (ISO)

trichostatin A (ISO)

triptonide (EXP)

troglitazone (EXP)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

ethanolamine metabolic process (IBA,IMP)

G protein-coupled receptor signaling pathway (ISO)

lipid metabolic process (IEA)

N-acylethanolamine metabolic process (IBA,IDA,IMP)

phospholipid metabolic process (IBA,IDA)

Cellular Component

cytoplasmic vesicle (IEA)

membrane (IDA,ISO)

membrane (ISO)

plasma membrane (IBA,IMP,ISS)

Molecular Function

glycerophosphodiester phosphodiesterase activity (IBA,IMP,ISS)

glycerophosphoinositol glycerophosphodiesterase activity (IDA,IMP)

hydrolase activity (IEA)

lysophospholipase activity (IDA)

metal ion binding (IEA)

phosphoric diester hydrolase activity (IDA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

glycerophospholipid metabolic pathway (ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal behavior (IEA)

abnormal enzyme/coenzyme activity (IAGP)

abnormal gait (IEA)

decreased mean corpuscular volume (IEA)

decreased startle reflex (IEA)

decreased vertical activity (IEA)

increased circulating alkaline phosphatase level (IEA)

increased circulating cholesterol level (IEA)

increased vertical activity (IEA)

preweaning lethality, incomplete penetrance (IEA)

prolonged QRS complex duration (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Functional annotation of a full-length mouse cDNA collection.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2.	MGDs mouse GO annotations	MGD data from the GO Consortium
3.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4.	SMPDB Annotation Import Pipeline	Pipeline to import SMPDB annotations from SMPDB into RGD
5.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	MIR16, a putative membrane glycerophosphodiester phosphodiesterase, interacts with RGS16.	Zheng B, etal., Proc Natl Acad Sci U S A 2000 Apr 11;97(8):3999-4004.

Additional References at PubMed

PMID:8889548	PMID:10349636	PMID:10725249	PMID:11042159	PMID:11076861	PMID:12477932	PMID:12576545	PMID:14610273	PMID:15489334	PMID:15782199	PMID:16141072	PMID:16141073
PMID:18227059	PMID:20393650	PMID:20797612	PMID:21267068	PMID:21801852	PMID:21873635	PMID:22052914	PMID:23425575	PMID:25596343	PMID:26067236

Genomics

Comparative Map Data

Gde1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	118,287,781 - 118,304,961 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	118,287,768 - 118,305,001 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	118,688,558 - 118,705,738 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	118,688,545 - 118,705,778 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	125,832,072 - 125,849,252 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	118,479,707 - 118,496,887 (-)	NCBI		MGSCv36	mm8
Celera	7	118,620,760 - 118,637,260 (-)	NCBI		Celera
Cytogenetic Map	7	F2	NCBI

GDE1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	19,501,693 - 19,522,098 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	16	19,501,693 - 19,522,123 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	19,513,015 - 19,533,420 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	19,420,516 - 19,440,951 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	19,420,517 - 19,440,951	NCBI
Celera	16	18,662,036 - 18,682,461 (-)	NCBI		Celera
Cytogenetic Map	16	p12.3	NCBI
HuRef	16	18,049,942 - 18,070,374 (-)	NCBI		HuRef
CHM1_1	16	19,600,278 - 19,620,704 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	16	19,432,571 - 19,452,970 (-)	NCBI		T2T-CHM13v2.0

Gde1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	173,016,984 - 173,032,396 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	172,954,394 - 173,032,429 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	181,329,538 - 181,344,924 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	1	188,515,643 - 188,531,029 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	1	181,245,807 - 181,261,211 (-)	NCBI	Rnor_WKY
Rnor_6.0	1	188,367,550 - 188,407,125 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	188,394,814 - 188,407,132 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	195,310,648 - 195,350,223 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	1	170,784,465 - 170,799,754 (-)	NCBI		Celera
Cytogenetic Map	1	q35	NCBI

Gde1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955442	3,186,440 - 3,219,092 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955442	3,186,440 - 3,219,092 (-)	NCBI	ChiLan1.0	ChiLan1.0

GDE1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	16	19,602,611 - 19,623,047 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	19,602,611 - 19,623,041 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	16	18,789,681 - 18,809,783 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

GDE1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	25,740,741 - 25,765,404 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	25,740,765 - 25,758,489 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	27,103,461 - 27,127,484 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	25,895,769 - 25,919,783 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	25,895,805 - 25,913,895 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	25,695,772 - 25,719,787 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	25,590,834 - 25,614,612 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	25,979,889 - 26,003,903 (+)	NCBI		UU_Cfam_GSD_1.0

Gde1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	117,079,632 - 117,096,259 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936501	5,176,909 - 5,193,543 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936501	5,177,511 - 5,193,484 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GDE1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	26,190,287 - 26,206,191 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	26,190,261 - 26,205,851 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	26,906,519 - 26,922,627 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GDE1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	17,782,202 - 17,802,966 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	17,781,214 - 17,802,894 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666068	12,127,594 - 12,149,062 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gde1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624782	2,838,164 - 2,860,568 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624782	2,838,151 - 2,859,789 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	363
Count of miRNA genes:	262
Interacting mature miRNAs:	302
Transcripts:	ENSMUST00000038791, ENSMUST00000132509
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
25314307	Mlh1fc2_m	MLH1 foci count 2 (mouse)					7	6502999	133501729	Mouse
12792978	Fbmd3_m	femoral bone mineral density 3, females only (mouse)					7	7050288	142367832	Mouse
10412199	Sst2_m	susceptibility to tuberculosis 2 (mouse)			Not determined		7	18728794	119485380	Mouse
1301158	Eae4_m	susceptibility to experimental allergic encephalomyelitis 4 (mouse)			Not determined		7	19147398	141919804	Mouse
10043926	Bw1n_m	body weight 1 in NSY (mouse)			Not determined		7	45161966	118693530	Mouse
13208555	Lgth10_m	body length 10 (mouse)					7	51649748	125599172	Mouse
27226751	Femd5_m	femur midshaft diameter 5, 10 week (mouse)					7	53249748	143153737	Mouse
27226778	Femd11_m	femur midshaft diameter 11, 16 week (mouse)					7	56949748	134001729	Mouse
26884408	Bzwq13_m	bi-zygomatic width QTL 13, 16 week (mouse)					7	61749748	121399223	Mouse
27095916	Scvln15_m	sacral vertebrae length 2, 16 week (mouse)					7	61749748	123699223	Mouse
26884440	Sklq4_m	skull length QTL 4, 5 week (mouse)					7	65249748	126499172	Mouse
27226715	Metcl3_m	metatarsal-calcaneal length 3, 5 week (mouse)					7	67849748	119499223	Mouse
26884444	Sklq8_m	skull length QTL 8, 10 week (mouse)					7	67849748	124199223	Mouse
26884451	Sklq14_m	skull length QTL 14, 16 week (mouse)					7	67849748	124999172	Mouse
27095907	Scvln4_m	sacral vertebrae length 2, 5 week (mouse)					7	69949748	120499223	Mouse
27095910	Pglq13_m	pelvic girdle length QTL 13, 16 week (mouse)					7	73049748	125699172	Mouse
27095933	Ulnl3_m	ulna length 3, 5 week (mouse)					7	73149748	143153737	Mouse
27226745	Metcl9_m	metatarsal-calcaneal length 9, 10 week (mouse)					7	74849748	122199223	Mouse
27226781	Tibl3_m	tibia length 3, 5 week (mouse)					7	74849748	122199223	Mouse
26884398	Humsd6_m	humerus midshaft diameter 6, 16 week (mouse)					7	78649748	136901729	Mouse
27095930	Ulnl10_m	ulna length 10, 16 week (mouse)					7	80849748	126699172	Mouse
27095923	Pglq3_m	pelvic girdle length QTL 3, 5 week (mouse)					7	81249748	124199223	Mouse
27095903	Scvln10_m	sacral vertebrae length 2, 10 week (mouse)					7	81449748	126499172	Mouse
27226765	Tibl18_m	tibia length 18, 16 week (mouse)					7	81849748	126499172	Mouse
27226763	Feml20_m	femur length 20, 16 week (mouse)					7	85049208	124199223	Mouse
1301647	Elpt_m	elevated leptin (mouse)			Not determined		7	86500186	120500329	Mouse
1301188	Heal6_m	wound healing/regeneration 6 (mouse)			Not determined		7	87043932	121044066	Mouse
1302062	Stheal6_m	soft tissue heal 6 (mouse)			Not determined		7	87043932	121044066	Mouse
13463473	Hbbcq4_m	hemoglobin concentration QTL 4 (mouse)					7	87043932	121044066	Mouse
1301781	Capsq3_m	capsaicin sensitivity related QTL 3 (mouse)			Not determined		7	87143137	119485380	Mouse
27226769	Tibl12_m	tibia length 12, 10 week (mouse)					7	87249208	126499172	Mouse
27226790	Feml15_m	femur length 15, 10 week (mouse)					7	87249208	126499172	Mouse
1357664	Nba3_m	New Zealand Black autoimmunity 3 (mouse)			Not determined		7	91482996	125483156	Mouse
1301937	Skull10_m	skull morphology 10 (mouse)			Not determined		7	91482996	125483156	Mouse
1300528	Ssial3_m	susceptibility to sialadenitis 3 (mouse)			Not determined		7	93391848	127392041	Mouse
1301478	Eae26_m	susceptibility to experimental allergic encephalomyelitis 26 (mouse)			Not determined		7	98164922	132165010	Mouse
13524850	Asrq7_m	acoustic startle response 7 (mouse)					7	98394974	132394974	Mouse
10412104	Tons2_m	tongue size 2 (mouse)			Not determined		7	99837716	133837716	Mouse
11039524	Tbbr3_m	Trypanosoma brucei brucei response 3 (mouse)					7	100750722	134750843	Mouse
1301447	Fembm3_m	femoral bone morphometry 3 (mouse)			Not determined		7	100993261	134993342	Mouse
1357460	Vtbt4_m	vertebral trabecular bone trait 4 (mouse)			Not determined		7	101693381	135693530	Mouse
1301105	Cfld4_m	cystic fibrosis lung disease 4 (mouse)			Not determined		7	101693381	135693530	Mouse
1300721	Cfbw3_m	cystic fibrosis body weight 3 (mouse)			Not determined		7	101693381	135693530	Mouse
4142312	Nilac4_m	nicotine induced locomotor activity 4 (mouse)			Not determined		7	102485219	136485380	Mouse
5491192	Mobq1_m	multigenic obesity QTL 1 (mouse)			Not determined		7	105250663	139250811	Mouse
13524852	Asrq7a_m	acoustic startle response 7a (mouse)					7	105350008	139350008	Mouse
4141056	Lskcn2_m	LSK cell number 2 (mouse)			Not determined			108482996	118693530	Mouse
14700684	Civq1_m	cerebral infarct volume QTL 1 (mouse)					7	109707335	143707335	Mouse
14700687	Civq5_m	cerebral infarct volume QTL 5 (mouse)					7	109707335	143707335	Mouse
14700688	Civq6_m	cerebral infarct volume QTL 6 (mouse)					7	109707335	143707335	Mouse
11059562	Lmr21b_m	leishmaniasis resistance 21b (mouse)					7	110967235	144967336	Mouse
10402499	Lmr21_m	leishmaniasis resistance 21 (mouse)			Not determined		7	110967235	144967336	Mouse
1302032	Alcp12_m	alcohol preference locus 12 (mouse)			Not determined		7	111166122	144995196	Mouse
1301898	Alcp14_m	alcohol preference locus 14 (mouse)			Not determined		7	111166122	144995196	Mouse
1300670	Sluc19_m	susceptibility to lung cancer 19 (mouse)			Not determined		7	111166122	144995196	Mouse
4142444	Femwf5_m	femur work to failure 5 (mouse)			Not determined			112552248	144995196	Mouse
1300747	Skts2_m	skin tumor susceptibility 2 (mouse)			Not determined		7	112922733	144995196	Mouse
38501072	Stsl7_m	Salmonella typhimurium susceptibility locus 7 (mouse)					7	115699235	128501724	Mouse
1300677	Bmd9_m	bone mineral density 9 (mouse)			Not determined		7	116634089	144995196	Mouse
15092059	Wogrme1_m	week one growth rate, maternal effect 1 (mouse)					7	117199227	134101729	Mouse
11059561	Lmr21a_m	leishmaniasis resistance 21a (mouse)					7	117750722	127967336	Mouse

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_019580	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC152412	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF212860	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK004583	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK005361	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK150807	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK177075	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK179749	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK186739	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK187418	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK193543	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK198453	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK204004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK205463	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK205654	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK206210	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK207806	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK212890	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK213531	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC003902	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466531	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSMUST00000038791 ⟹ ENSMUSP00000046371

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	7	118,287,768 - 118,305,001 (-)	Ensembl
GRCm38.p6 Ensembl	7	118,688,545 - 118,705,778 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000132509 ⟹ ENSMUSP00000122015

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	7	118,288,334 - 118,304,603 (-)	Ensembl
GRCm38.p6 Ensembl	7	118,689,111 - 118,705,380 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000207323 ⟹ ENSMUSP00000147236

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	7	118,290,956 - 118,304,983 (-)	Ensembl
GRCm38.p6 Ensembl	7	118,691,733 - 118,705,760 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000208040 ⟹ ENSMUSP00000147251

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	7	118,290,825 - 118,304,971 (-)	Ensembl
GRCm38.p6 Ensembl	7	118,691,602 - 118,705,748 (-)	Ensembl

RefSeq Acc Id:

NM_019580 ⟹ NP_062526

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	7	118,287,781 - 118,304,961 (-)	NCBI
GRCm38	7	118,688,558 - 118,705,738 (-)	ENTREZGENE
MGSCv37	7	125,832,072 - 125,849,252 (-)	RGD
Celera	7	118,620,760 - 118,637,260 (-)	RGD
cM Map	7		ENTREZGENE

Sequence:

show sequence

GGAGGGTTCCGGCTGTGGCCAGTACCTCGGCGTCTACGCGTCGCCCGGCAGGTCCGGGGCTCCG
GTCCGTGCCGGTGCAGGCGCCGGCATGTGGCTGTGGGAGGACCAGGGCGGCCTCCTGGGCCCCT
TCTCCTTCGTGCTGGTGCTGCTGCTGGTGGTGACACGCAGCCCCTTCAACGCCTGCGTGCTCAC
CGGCAGCCTCTACATCCTGCTGCGGTTCTTCAGCTTCGAGCCGGTGCCGTCCCGCCGGGCCCTG
CAGGTGCTCAAGCCCCGTGACCGCGTGTCCGCCATCGCCCATCGCGGCGGCAGCCACGACGCGC
CCGAGAACACGCTGGCGGCCATCCGGCAGGCAGCTAAGAATGGAGCAACAGGTGTGGAGCTGGA
CATCGAGTTTACTTCTGATGGAGTTCCTGTCTTGATGCACGATAACACAGTAGATAGGACAACA
GACGGGTCTGGCCGACTATGTGATCTGACATTTGAACAAGTTAGGAAACTTAACCCTGCAGCAA
ATCACAGACTCAGAAACGAGTTCCCTGATGAAAGGATCCCTACCCTGAAGGAAGCTGTCACAGA
GTGCCTCCGCCATAACCTCACCATCTTCTTTGATGTCAAAGGCCATGCAGATATGGCTTCTGCT
GCTCTAAAGAATATATACACGGAATTTCCACAGCTGTACAATAACAGTATGGTCTGCTCATTCT
TGCCGGAAGTCATCTATAAAATGAGACAAACGGATCAGAAGGTAATCACAGCCCTAACTCACAG
GCCTTGGAGCCTGAGCCACACTGGAGATGGGAAGCCTCGCTACAGCGTCTTTTGGAAGCAGTCT
GTGTTTGTGGTGTTGGACATCTTGCTGGACTGGAGCATGCACAATGTCTTGTGGTACCTGTGTG
GGATTTCAGCCTTCCTCATGCAGAAGGATTTTGTCTCCCCGGACTATTTGAAGAAGTGGTCAGC
TAAAGGAATCCAGGTTGTGAGTTGGACTGTCAATACCTTTGATGAAAAGAATTACTACGAGTCC
CACCTTGGGTCCAGCTACATCACTGACAGCATGCTAGAAGACTGTGCACCTCACTTCTAGACTC
CCCAGGAGGAAACACAGTTGCGAAACTGCCTGGAGGCCTCTTGCAGGGACATGAGAACACTCTG
TTAGCACAAGCCCTGGGGACCCTGTGGCTCATACTAGCAATAGTCACAGTGTCACCCCAACAAG
CAGAAACCAGGCATGGTGACCATGCTCCAAGGAAGGCTCCACACTTGCCCTTAAAATTCTGGAT
CTGCAAAAAGGCAGGGTGGCCCCACCCTGACCCCGCTGAGGGTACAGAGCCACGAGGATGAGCA
GAGTGGGTCCTGCAATTAGGGCGCAGGCACCAATGCATGGGGCTTGCATGATCACTCCAAGTTG
ACATTTTAAATCTTGCCGTACTTCAGTAATTCACTTATTTCCAATATTTGTCGTCAGCTTTGTT
AATGGCGACCTGTAGGTGTCAAACTTGTGACCACACTAATAAAATCATTGAAAGGTG

hide sequence

Protein Sequences


Protein RefSeqs	NP_062526	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAF65232	(Get FASTA)	NCBI Sequence Viewer
	AAH03902	(Get FASTA)	NCBI Sequence Viewer
	BAB23975	(Get FASTA)	NCBI Sequence Viewer
	BAE29870	(Get FASTA)	NCBI Sequence Viewer
	EDL17135	(Get FASTA)	NCBI Sequence Viewer
	EDL17136	(Get FASTA)	NCBI Sequence Viewer
	EDL17137	(Get FASTA)	NCBI Sequence Viewer
	Q9JL56	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_062526 ⟸ NM_019580

- UniProtKB:

Q3UBU4 (UniProtKB/Swiss-Prot), Q9JL56 (UniProtKB/Swiss-Prot), A0A6P5Q6E5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MWLWEDQGGLLGPFSFVLVLLLVVTRSPFNACVLTGSLYILLRFFSFEPVPSRRALQVLKPRDR
VSAIAHRGGSHDAPENTLAAIRQAAKNGATGVELDIEFTSDGVPVLMHDNTVDRTTDGSGRLCD
LTFEQVRKLNPAANHRLRNEFPDERIPTLKEAVTECLRHNLTIFFDVKGHADMASAALKNIYTE
FPQLYNNSMVCSFLPEVIYKMRQTDQKVITALTHRPWSLSHTGDGKPRYSVFWKQSVFVVLDIL
LDWSMHNVLWYLCGISAFLMQKDFVSPDYLKKWSAKGIQVVSWTVNTFDEKNYYESHLGSSYIT
DSMLEDCAPHF

hide sequence

RefSeq Acc Id:

ENSMUSP00000122015 ⟸ ENSMUST00000132509

RefSeq Acc Id:

ENSMUSP00000147251 ⟸ ENSMUST00000208040

RefSeq Acc Id:

ENSMUSP00000147236 ⟸ ENSMUST00000207323

RefSeq Acc Id:

ENSMUSP00000046371 ⟸ ENSMUST00000038791

Protein Domains

GP-PDE

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9JL56-F1-model_v2	AlphaFold	Q9JL56	1-331	view protein structure

Promoters

RGD ID:

8665359

Promoter ID:

EPDNEW_M10711

Type:

initiation region

Name:

Gde1_1

Description:

Mus musculus glycerophosphodiester phosphodiesterase 1 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	7	118,705,760 - 118,705,820	EPDNEW

RGD ID:

6841167

Promoter ID:

MM_KWN:52443

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day1, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6

Transcripts:

OTTMUST00000056450, OTTMUST00000056451

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	7	125,848,989 - 125,849,489 (-)	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1891827	AgrOrtholog
Ensembl Genes	ENSMUSG00000033917	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSMUSP00000046371	ENTREZGENE
	ENSMUSP00000046371.9	UniProtKB/Swiss-Prot
	ENSMUSP00000122015.3	UniProtKB/TrEMBL
	ENSMUSP00000147236.2	UniProtKB/TrEMBL
	ENSMUSP00000147251.2	UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000038791	ENTREZGENE
	ENSMUST00000038791.15	UniProtKB/Swiss-Prot
	ENSMUST00000132509.4	UniProtKB/TrEMBL
	ENSMUST00000207323.2	UniProtKB/TrEMBL
	ENSMUST00000208040.2	UniProtKB/TrEMBL
Gene3D-CATH	3.20.20.190	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	GP_PDE_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PLC-like_Pdiesterase_TIM-brl	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:56209	UniProtKB/Swiss-Prot
MGD	MGI:1891827	ENTREZGENE
NCBI Gene	56209	ENTREZGENE
PANTHER	GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 1	UniProtKB/Swiss-Prot
	GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 1	UniProtKB/Swiss-Prot
	GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 1	UniProtKB/TrEMBL
	GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 1	UniProtKB/TrEMBL
Pfam	GDPD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Gde1	PhenoGen
PROSITE	GP_PDE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF51695	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A140LJJ4_MOUSE	UniProtKB/TrEMBL
	A0A140LJK8_MOUSE	UniProtKB/TrEMBL
	A0A6P5Q6E5	ENTREZGENE
	D3Z3E2_MOUSE	UniProtKB/TrEMBL
	GDE1_MOUSE	UniProtKB/Swiss-Prot
	Q3UBU4	ENTREZGENE
	Q9JL56	ENTREZGENE
UniProt Secondary	Q3UBU4	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - SMPDB

Mammalian Phenotype

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Imported Disease Annotations - ClinVar

Imported Annotations - SMPDB

Mammalian Phenotype