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Gene: Scly (selenocysteine lyase) Mus musculus
Symbol: Scly
Name: selenocysteine lyase
Description: Predicted to have several functions, including protein homodimerization activity; selenocysteine lyase activity; and vitamin B6 binding activity. Involved in several processes, including negative regulation of cellular response to oxidative stress; response to insulin; and selenium compound metabolic process. Predicted to localize to the catalytic complex. Is expressed in alimentary system; liver; and nervous system. Orthologous to human SCLY (selenocysteine lyase); PARTICIPATES IN selenoamino acid metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; bis(2-chloroethyl) sulfide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9830169H08; A930015N15Rik; mSCL; SCL; Scly1; Scly2; selenocysteine reductase
Homo sapiens (human) : SCLY (selenocysteine lyase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Scly (selenocysteine lyase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Scly (selenocysteine lyase)
Pan paniscus (bonobo/pygmy chimpanzee) : SCLY (selenocysteine lyase)
Canis lupus familiaris (dog) : SCLY (selenocysteine lyase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Scly (selenocysteine lyase)
Sus scrofa (pig) : SCLY (selenocysteine lyase)
more info ...
Related Pseudogenes: Gm17992  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl191,298,338 - 91,321,075 (+)Ensembl
GRCm38191,298,295 - 91,321,080 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37193,194,915 - 93,217,657 (+)NCBIGRCm37mm9NCBIm37
MGSCv36193,128,744 - 93,151,480 (+)NCBImm8
Celera194,235,440 - 94,258,187 (+)NCBICelera
Cytogenetic Map1 DNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Scly
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1552754
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.