Apoc3 (apolipoprotein C-III) - Rat Genome Database

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Gene: Apoc3 (apolipoprotein C-III) Mus musculus
Analyze
Symbol: Apoc3
Name: apolipoprotein C-III
RGD ID: 10179
MGI Page MGI
Description: Predicted to have high-density lipoprotein particle receptor binding activity; lipase inhibitor activity; and phospholipid binding activity. Involved in cholesterol metabolic process; triglyceride catabolic process; and triglyceride mobilization. Predicted to localize to chylomicron; spherical high-density lipoprotein particle; and triglyceride-rich plasma lipoprotein particle. Human ortholog(s) of this gene implicated in several diseases, including apolipoprotein C-III deficiency; chronic kidney disease; coronary artery disease; familial hyperlipidemia (multiple); and glucose metabolism disease (multiple). Orthologous to human APOC3 (apolipoprotein C3).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: apo-CIII; Apoc; apoC-III; apolipoprotein C3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39946,144,348 - 46,146,934 (-)NCBIGRCm39mm39
GRCm39 Ensembl946,144,231 - 46,146,934 (-)Ensembl
GRCm38946,233,050 - 46,235,636 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl946,232,933 - 46,235,636 (-)EnsemblGRCm38mm10GRCm38
MGSCv37946,041,134 - 46,043,380 (-)NCBIGRCm37mm9NCBIm37
MGSCv36945,984,046 - 45,986,292 (-)NCBImm8
Celera943,522,002 - 43,524,237 (-)NCBICelera
Cytogenetic Map9A5.2NCBI
cM Map925.36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-ephedrine  (ISO)
1-methylphenanthrene  (ISO)
1-nitropropane  (ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-diaminotoluene  (ISO)
2,6-diaminotoluene  (ISO)
2-acetamidofluorene  (ISO)
2-nitro-p-phenylenediamine  (ISO)
2-nitropropane  (ISO)
3,7-dihydropurine-6-thione  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-acetylaminofluorene  (ISO)
4-hydroxyphenyl retinamide  (EXP)
4-nitro-1,2-phenylenediamine  (ISO)
acetamide  (ISO)
aconitine  (ISO)
aflatoxin B1  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bexarotene  (ISO)
bezafibrate  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bromobenzene  (ISO)
buta-1,3-diene  (EXP)
butanal  (ISO)
caffeine  (ISO)
calcium dichloride  (ISO)
captan  (EXP)
carbon nanotube  (EXP)
chenodeoxycholic acid  (EXP)
choline  (EXP)
chromium(6+)  (EXP)
cisplatin  (EXP,ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
daunorubicin  (ISO)
dexamethasone  (EXP,ISO)
diamminedichloroplatinum  (ISO)
dibenz[a,h]anthracene  (ISO)
dibenzo[a,l]pyrene  (ISO)
ethanol  (ISO)
fenofibrate  (EXP,ISO)
fluoranthene  (ISO)
folpet  (EXP)
furan  (ISO)
gemfibrozil  (ISO)
ginsenoside Rf  (EXP)
high-density lipoprotein cholesterol  (ISO)
hydrazine  (ISO)
hydrogen peroxide  (ISO)
L-methionine  (EXP)
linalool  (EXP,ISO)
menadione  (ISO)
mercaptopurine  (ISO)
methapyrilene  (ISO)
methylmercury chloride  (ISO)
microcystin-LR  (EXP)
N-nitrosodiethylamine  (ISO)
nickel atom  (ISO)
O-methyleugenol  (ISO)
obeticholic acid  (ISO)
olanzapine  (ISO)
oleic acid  (ISO)
oxybenzone  (ISO)
p-toluidine  (ISO)
paracetamol  (ISO)
perfluorononanoic acid  (EXP)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (ISO)
pioglitazone  (ISO)
pirinixic acid  (EXP,ISO)
potassium dichromate  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
purine-6-thiol  (ISO)
quercetin  (ISO)
simvastatin  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (EXP)
Tesaglitazar  (ISO)
testosterone  (ISO)
tetrachloroethene  (EXP)
tetrachloromethane  (ISO)
tetracycline  (EXP)
tetramethylpyrazine  (ISO)
titanium dioxide  (EXP)
transplatin  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cellular response to glucose stimulus  (ISO)
cholesterol efflux  (ISO)
cholesterol homeostasis  (IBA)
cholesterol metabolic process  (IMP)
chylomicron remnant clearance  (ISO)
G protein-coupled receptor signaling pathway  (ISO)
high-density lipoprotein particle remodeling  (ISO)
inflammatory response  (ISO)
lipid catabolic process  (IEA)
lipid metabolic process  (IEA)
lipid transport  (IEA)
lipoprotein metabolic process  (IEA)
lipoprotein transport  (ISO)
negative regulation of cholesterol import  (ISO)
negative regulation of fatty acid biosynthetic process  (ISO)
negative regulation of high-density lipoprotein particle clearance  (IBA)
negative regulation of lipid catabolic process  (ISO)
negative regulation of lipid metabolic process  (ISO)
negative regulation of lipoprotein lipase activity  (IBA)
negative regulation of low-density lipoprotein particle clearance  (IBA)
negative regulation of oxidative phosphorylation  (ISO)
negative regulation of receptor-mediated endocytosis  (ISO)
negative regulation of triglyceride catabolic process  (IBA)
negative regulation of very-low-density lipoprotein particle clearance  (IBA)
negative regulation of very-low-density lipoprotein particle remodeling  (ISO)
phospholipid efflux  (ISO)
positive regulation of triglyceride biosynthetic process  (ISO)
regulation of Cdc42 protein signal transduction  (ISO)
response to drug  (ISO)
response to fatty acid  (ISO)
response to nutrient  (ISO)
response to peptide hormone  (ISO)
response to triglyceride  (ISO)
response to vitamin A  (ISO)
triglyceride catabolic process  (IMP,ISO)
triglyceride homeostasis  (IBA)
triglyceride metabolic process  (IMP,ISO)
triglyceride mobilization  (IMP)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. al Muhtaseb N, etal., Pediatrics. 1992 May;89(5 Pt 1):936-41.
2. Becker KG, etal., Nat Genet. 2004 May;36(5):431-2.
3. Dallinga-Thie GM, etal., J Clin Invest. 1997 Mar 1;99(5):953-61.
4. Dallongeville J, etal., Int J Cardiol. 2006 Jan 13;106(2):152-6.
5. Duivenvoorden I, etal., Diabetes. 2005 Mar;54(3):664-71.
6. Florez H, etal., Atherosclerosis. 2006 Sep;188(1):134-41. Epub 2005 Nov 18.
7. Gerritsen G, etal., J Lipid Res. 2005 Jul;46(7):1466-73. Epub 2005 May 1.
8. Graham MJ, etal., Circ Res. 2013 May 24;112(11):1479-90. doi: 10.1161/CIRCRESAHA.111.300367. Epub 2013 Mar 29.
9. Henderson HE, etal., Hum Genet. 1987 Jan;75(1):62-5.
10. Hokanson JE, etal., Diabetes. 2006 Mar;55(3):834-8.
11. Holmberg R, etal., Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10685-9. doi: 10.1073/pnas.1019553108. Epub 2011 Jun 13.
12. Hughes TA, etal., Metabolism. 1994 Mar;43(3):333-47.
13. Inoue T, etal., Invest Ophthalmol Vis Sci. 2013 Aug 9;54(8):5353-8. doi: 10.1167/iovs.13-12245.
14. Jong MC, etal., Arterioscler Thromb Vasc Biol. 1999 Mar;19(3):472-84.
15. Joven J, etal., Nephron. 1993;64(4):565-9.
16. Kamisako T and Ogawa H, J Gastroenterol Hepatol. 2007 Jan;22(1):125-31.
17. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
18. Kee F, etal., Atherosclerosis. 1999 Jul;145(1):187-95.
19. Kim J, etal., BMB Rep. 2010 Aug;43(8):535-40.
20. Klein RL, etal., J Diabetes Complications. 2005 Jan-Feb;19(1):18-25.
21. Konemori G, etal., Nippon Ronen Igakkai Zasshi. 1990 Jan;27(1):22-7.
22. Lee DM, etal., PLoS One. 2011;6(7):e22360. doi: 10.1371/journal.pone.0022360. Epub 2011 Jul 28.
23. Lin-Lee YC, etal., J Lipid Res. 1993 Feb;34(2):249-59.
24. Liu HK, etal., Yi Chuan Xue Bao. 2005 Jan;32(1):11-8.
25. MGD and Homologene mouse data transfer
26. MGD data from the GO Consortium
27. MGD IEA
28. Miller M, etal., Arch Med Res. 2007 May;38(4):444-51. Epub 2007 Mar 26.
29. Morgan PE, etal., Free Radic Res. 2007 Dec;41(12):1301-12.
30. Ng MC, etal., Clin Genet. 2006 Jul;70(1):20-8.
31. Nowakowska Fortuna E, etal., Kidney Blood Press Res. 2011;34(5):311-9. doi: 10.1159/000325648. Epub 2011 May 26.
32. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
33. OMIM Disease Annotation Pipeline
34. Ooi EM, etal., J Lipid Res. 2011 Apr;52(4):794-800. doi: 10.1194/jlr.M011163. Epub 2011 Feb 6.
35. RGD automated import pipeline
36. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
37. RGD automated import pipeline for gene-chemical interactions
38. Rodrigo E, etal., Transplant Proc. 2002 Feb;34(1):379.
39. Sedova L, etal., Int J Obes Relat Metab Disord. 2004 May;28(5):719-25.
40. Shimokata K, etal., Atherosclerosis. 2004 Jan;172(1):167-73.
41. Singh P, etal., Diab Vasc Dis Res. 2007 Jun;4(2):124-9.
42. Smith CE, etal., PLoS One. 2009;4(5):e5465. doi: 10.1371/journal.pone.0005465. Epub 2009 May 8.
43. Tahvanainen E, etal., Arterioscler Thromb Vasc Biol. 1998 Nov;18(11):1810-7.
44. Takahashi H, etal., Acta Paediatr Jpn. 1996 Dec;38(6):634-9.
45. Tornero F, etal., Nefrologia. 2000 Jan-Feb;20(1):47-53.
46. Wang J, etal., Mol Biol Rep. 2012 May;39(5):5095-104. doi: 10.1007/s11033-011-1305-1. Epub 2011 Dec 8.
47. Yamada Y, etal., Mol Genet Metab. 2004 Apr;81(4):282-90.
48. Zeng Q, etal., Hum Genet. 1995 Apr;95(4):371-5.
Additional References at PubMed
PMID:1450516   PMID:1478650   PMID:6099394   PMID:7035547   PMID:7868970   PMID:8089130   PMID:8689583   PMID:8864964   PMID:8994037   PMID:9616220   PMID:9873036   PMID:10349636  
PMID:11002334   PMID:11042159   PMID:11076861   PMID:11478940   PMID:11551841   PMID:11557675   PMID:11590213   PMID:11814582   PMID:11983814   PMID:12477932   PMID:12810823   PMID:14610273  
PMID:14974682   PMID:14983036   PMID:15117734   PMID:15489334   PMID:15649902   PMID:16141072   PMID:16141073   PMID:16461842   PMID:16478678   PMID:16497661   PMID:16498401   PMID:17916774  
PMID:18243209   PMID:18263930   PMID:18678879   PMID:18722179   PMID:19121312   PMID:19542564   PMID:20889132   PMID:21183731   PMID:21793029   PMID:21873635   PMID:23949443   PMID:24449835  
PMID:24929016   PMID:25209997   PMID:25941406   PMID:25969427   PMID:26160324   PMID:27226540   PMID:27400128   PMID:28115523   PMID:28159868   PMID:28739253   PMID:28825717   PMID:28887372  
PMID:29449313   PMID:30223835   PMID:31092690   PMID:31295146  


Genomics

Comparative Map Data
Apoc3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39946,144,348 - 46,146,934 (-)NCBIGRCm39mm39
GRCm39 Ensembl946,144,231 - 46,146,934 (-)Ensembl
GRCm38946,233,050 - 46,235,636 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl946,232,933 - 46,235,636 (-)EnsemblGRCm38mm10GRCm38
MGSCv37946,041,134 - 46,043,380 (-)NCBIGRCm37mm9NCBIm37
MGSCv36945,984,046 - 45,986,292 (-)NCBImm8
Celera943,522,002 - 43,524,237 (-)NCBICelera
Cytogenetic Map9A5.2NCBI
cM Map925.36NCBI
APOC3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl11116,829,706 - 116,833,072 (+)EnsemblGRCh38hg38GRCh38
GRCh3811116,829,907 - 116,833,072 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711116,700,623 - 116,703,788 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611116,205,834 - 116,208,997 (+)NCBINCBI36hg18NCBI36
Build 3411116,205,833 - 116,208,997NCBI
Celera11113,858,439 - 113,861,589 (+)NCBI
Cytogenetic Map11q23.3NCBI
HuRef11112,632,897 - 112,636,045 (+)NCBIHuRef
CHM1_111116,585,371 - 116,588,539 (+)NCBICHM1_1
Apoc3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2846,531,478 - 46,533,658 (-)NCBI
Rnor_6.0 Ensembl850,529,318 - 50,531,498 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0850,529,318 - 50,531,498 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0849,155,390 - 49,157,779 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.18159,618,812 - 159,618,833NCBI
Celera846,113,508 - 46,115,688 (-)NCBICelera
Cytogenetic Map8q22NCBI
Apoc3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541218,165,667 - 18,168,015 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541218,165,667 - 18,168,015 (+)NCBIChiLan1.0ChiLan1.0
APOC3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.111115,600,416 - 115,603,460 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11115,600,416 - 115,603,460 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v011111,667,816 - 111,670,861 (+)NCBIMhudiblu_PPA_v0panPan3
APOC3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1516,744,423 - 16,746,992 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl516,744,423 - 16,746,992 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha516,796,585 - 16,799,154 (-)NCBI
ROS_Cfam_1.0516,690,907 - 16,693,492 (-)NCBI
UMICH_Zoey_3.1516,828,006 - 16,830,575 (-)NCBI
UNSW_CanFamBas_1.0516,730,571 - 16,733,151 (-)NCBI
UU_Cfam_GSD_1.0516,773,507 - 16,776,068 (-)NCBI
Apoc3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494799,184,897 - 99,187,178 (+)NCBI
SpeTri2.0NW_0049365422,106,927 - 2,108,412 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
APOC3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1944,211,171 - 44,213,538 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2949,283,407 - 49,285,786 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap9p13NCBI
APOC3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11108,196,283 - 108,199,274 (+)NCBI
ChlSab1.1 Ensembl1108,196,939 - 108,199,342 (+)Ensembl
Apoc3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478412,244,565 - 12,246,790 (+)NCBI

Position Markers
D9Mit93  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38946,233,355 - 46,233,567UniSTSGRCm38
MGSCv37946,041,438 - 46,041,650UniSTSGRCm37
Celera943,522,306 - 43,522,506UniSTS
Cytogenetic Map9A5.2UniSTS
cM Map927.0UniSTS
Whitehead Genetic920.8UniSTS
Whitehead_YAC9 UniSTS
PMC123053P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38946,232,846 - 46,233,270UniSTSGRCm38
MGSCv37946,040,929 - 46,041,353UniSTSGRCm37
Celera943,521,797 - 43,522,221UniSTS
Cytogenetic Map9A5.2UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300532Tbs2_mtuberculosis severity 2 (mouse)Not determined91245867446458818Mouse
10043917Obq37_mobesity QTL 37 (mouse)Not determined91347987947479879Mouse
1357637Si5lq2_mserum IGFBP-5 level QTL 2 (mouse)Not determined91550045549500594Mouse
4141447Cfmq2_mcystic fibrosis modifier QTL 2 (mouse)Not determined91550045549500594Mouse
4141591Cq4_mcholesterol QTL 4 (mouse)Not determined91550045549500594Mouse
1301421Lgth4_mbody length 4 (mouse)Not determined91550045549500594Mouse
11354951Pdcc3_mplasmacytoid dentritic cell compartment 3 (mouse)91583833149838331Mouse
12790993Adq1_maortic diameter QTL 1 (mouse)91583833149838331Mouse
12790997Adq2_maortic diameter QTL 2 (mouse)91583833149838331Mouse
12880415V125Dq7_mvitamin D active form serum level QTL 7 (mouse)91610000050100000Mouse
12880416V125Dq8_mvitamin D active form serum level QTL 8 (mouse)91610000050100000Mouse
13504834Hdlq109_mHDL QTL 109 (mouse)91679834550798345Mouse
1357465Vtbt6_mvertebral trabecular bone trait 6 (mouse)Not determined91706754451067647Mouse
1300643Pvcan2_mprotection against vaginal candidiasis 2 (mouse)Not determined92003211054032229Mouse
1301439Morph2_mmorphine antinociception 2 (mouse)Not determined92024206654242196Mouse
1301045Sluc10_msusceptibility to lung cancer 10 (mouse)Not determined92039490154395074Mouse
1301883Skull12_mskull morphology 12 (mouse)Not determined92039490154395074Mouse
4142352Lmr17_mleishmaniasis resistance 17 (mouse)Not determined92039490154395074Mouse
10043950Pbft5_mpercent body fat 5 (mouse)Not determined92039490154395074Mouse
12904939Edlmmq8_mextensor digitorum longus muscle mass QTL 8 (mouse)92094144454941444Mouse
13208563Bmiq8_mbody mass index QTL 8 (mouse)92500000069000000Mouse
11532694Sluc39a_msusceptibility to lung cancer 39a (mouse)92567618959676285Mouse
11532695Sluc39b_msusceptibility to lung cancer 39b (mouse)92567618959676285Mouse
11532696Sluc39c_msusceptibility to lung cancer 39c (mouse)92567618959676285Mouse
11532712Sluc39d_msusceptibility to lung cancer 39d (mouse)92567618959676285Mouse
1300932Hdlq17_mHDL QTL 17 (mouse)Not determined92688512460885255Mouse
10043867Mtbcq9_mmultiple trait body composition QTL 9 (mouse)Not determined92688512460885255Mouse
10043987Stheal13_msoft tissue heal 13 (mouse)Not determined92688512460885255Mouse
10043878Adip20_madiposity 20 (mouse)Not determined92733989761340026Mouse
10043847Hdlq89_mHDL QTL 89 (mouse)Not determined92938163163381774Mouse
1301782Chol11_mcholesterol 11 (mouse)Not determined92938163163381774Mouse
1301365Ap5q_malcohol preference 5 QTL (mouse)Not determined93014186664141979Mouse
1357746Vtbt7_mvertebral trabecular bone trait 7 (mouse)Not determined93082861764828723Mouse
1302180Actd4_mactivity-distance traveled 4 (mouse)Not determined93252326366523557Mouse
4141148Cq5_mcholesterol QTL 5 (mouse)Not determined93254112166541246Mouse
1301692Hts_mhypothermia sensitivity (mouse)Not determined93259987266600121Mouse
4141323Ptnu3_mproteinuria 3 (mouse)Not determined93297840266978536Mouse
1357709Si5lq3_mserum IGFBP-5 level QTL 3 (mouse)Not determined93319972567199840Mouse
1558872Ibdq1_minflammatory bowel disease QTL 1 (mouse)Not determined93406754473531973Mouse
1301252Etohc3_methanol consumption 3 (mouse)Not determined93512317869123299Mouse
1301972Cocrb8_mcocaine related behavior 8 (mouse)Not determined93512317869123299Mouse
1558968Tbdr1_mbody temperature response to dietary restriction, QTL 1 (mouse)Not determined93512317869123299Mouse
10045613Rapop7_mradiation-induced apoptosis 6 (mouse)Not determined93682494749509211Mouse
1301501Lmr2_mleishmaniasis resistance 2 (mouse)Not determined93703211050199840Mouse
4142042Alpq3_malcohol preference QTL 3 (mouse)Not determined93739490198819654Mouse
10043971Obq32_mobesity QTL 32 (mouse)Not determined93791224471912244Mouse
12791002Arlsq2_maortic root lesion size QTL 2 (mouse)93819229172192291Mouse
12790986Pcho9_mplasma cholesterol 9 (mouse)93819229172192291Mouse
12790992Arlsq1_maortic root lesion size QTL 1 (mouse)93819229172192291Mouse
12738449Spcq2_msperm count QTL 2 (mouse)93949260173492601Mouse
1558993Tdmq1_mtype 2 diabetes modifying QTL 1 (mouse)Not determined94050829851897370Mouse
4141071Ath29_matherosclerosis 29 (mouse)Not determined94050829874700643Mouse
11532693Sluc39_msusceptibility to lung cancer 39 (mouse)94073407848440176Mouse
1301702Brm1_mbrachyury modifier 1 (mouse)Not determined94089776474897921Mouse
1301558Stheal8_msoft tissue heal 8 (mouse)Not determined94357343177573577Mouse
10045639Heal28_mwound healing/regeneration 28 (mouse)Not determined94357343177573577Mouse
1301435Trigq1_mtriglyceride QTL 1 (mouse)Not determined94452089278520980Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:827
Count of miRNA genes:377
Interacting mature miRNAs:416
Transcripts:ENSMUST00000034586, ENSMUST00000118649, ENSMUST00000121916, ENSMUST00000145672
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000034586   ⟹   ENSMUSP00000034586
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl946,233,051 - 46,235,299 (-)Ensembl
RefSeq Acc Id: ENSMUST00000118649   ⟹   ENSMUSP00000113058
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl946,233,198 - 46,235,636 (-)Ensembl
RefSeq Acc Id: ENSMUST00000121916   ⟹   ENSMUSP00000113126
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl946,232,933 - 46,235,260 (-)Ensembl
RefSeq Acc Id: ENSMUST00000145672   ⟹   ENSMUSP00000115025
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl946,234,437 - 46,235,469 (-)Ensembl
RefSeq Acc Id: ENSMUST00000214729
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl946,233,060 - 46,235,299 (-)Ensembl
RefSeq Acc Id: NM_001289755   ⟹   NP_001276684
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39946,144,348 - 46,146,597 (-)NCBI
GRCm38946,233,050 - 46,235,299 (-)NCBI
Celera943,522,001 - 43,524,576 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001289756   ⟹   NP_001276685
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39946,144,348 - 46,146,934 (-)NCBI
GRCm38946,233,050 - 46,235,636 (-)NCBI
Celera943,522,001 - 43,524,576 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001289833   ⟹   NP_001276762
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39946,144,348 - 46,146,597 (-)NCBI
GRCm38946,233,050 - 46,235,299 (-)NCBI
Celera943,522,001 - 43,524,576 (-)NCBI
Sequence:
RefSeq Acc Id: NM_023114   ⟹   NP_075603
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39946,144,348 - 46,146,597 (-)NCBI
GRCm38946,233,050 - 46,235,299 (-)NCBI
MGSCv37946,041,134 - 46,043,380 (-)RGD
Celera943,522,001 - 43,524,576 (-)NCBI
cM Map9 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_075603   ⟸   NM_023114
- Peptide Label: isoform b precursor
- UniProtKB: P33622 (UniProtKB/Swiss-Prot),   A0A0R4J1N3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001276685   ⟸   NM_001289756
- Peptide Label: isoform b precursor
- UniProtKB: P33622 (UniProtKB/Swiss-Prot),   A0A0R4J1N3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001276762   ⟸   NM_001289833
- Peptide Label: isoform c
- Sequence:
RefSeq Acc Id: NP_001276684   ⟸   NM_001289755
- Peptide Label: isoform a
- UniProtKB: E9QP56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000113058   ⟸   ENSMUST00000118649
RefSeq Acc Id: ENSMUSP00000034586   ⟸   ENSMUST00000034586
RefSeq Acc Id: ENSMUSP00000115025   ⟸   ENSMUST00000145672
RefSeq Acc Id: ENSMUSP00000113126   ⟸   ENSMUST00000121916

Promoters
RGD ID:6849264
Promoter ID:MM_XEF:7428
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:NM_000040,   NM_001003369,   NM_012501
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36946,042,436 - 46,042,936 (-)MPROMDB
RGD ID:6844175
Promoter ID:MM_KWN:57218
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:ENSMUST00000118649,   ENSMUST00000121916,   OTTMUST00000071084,   OTTMUST00000071087
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36946,043,036 - 46,043,536 (-)MPROMDB
RGD ID:8669478
Promoter ID:EPDNEW_M12770
Type:initiation region
Name:Apoc3_1
Description:Mus musculus apolipoprotein C-III , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38946,235,299 - 46,235,359EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:88055 AgrOrtholog
Ensembl Genes ENSMUSG00000032081 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000034586 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000113058 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000113126 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000115025 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000034586 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000118649 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000121916 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000145672 UniProtKB/TrEMBL
  ENSMUST00000214729 ENTREZGENE
Gene3D-CATH 1.10.225.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Apo-CIII UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Apo_CIII_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:11814 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:88055 ENTREZGENE
NCBI Gene 11814 ENTREZGENE
PANTHER PTHR14225 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Apo-CIII UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB APOC3 RGD
PhenoGen Apoc3 PhenoGen
UniProt A0A0R4J1N3 ENTREZGENE, UniProtKB/TrEMBL
  APOC3_MOUSE UniProtKB/Swiss-Prot
  D3YXN8_MOUSE UniProtKB/TrEMBL
  E9QP56 ENTREZGENE, UniProtKB/TrEMBL
  P33622 ENTREZGENE
UniProt Secondary Q8VC58 UniProtKB/Swiss-Prot
  Q9CPP9 UniProtKB/Swiss-Prot