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Gene: Aqp3 (aquaporin 3) Mus musculus
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Symbol: Aqp3
Name: aquaporin 3
RGD ID: 68639
Description: Predicted to have glycerol channel activity; urea transmembrane transporter activity; and water channel activity. Involved in several processes, including cellular response to oxygen-glucose deprivation; glycerol transport; and renal water absorption. Localizes to basolateral plasma membrane and cell-cell junction. Is expressed in several structures, including alimentary system; early conceptus; gonad; lateral plate mesoderm; and metanephros. Used to study nephrogenic diabetes insipidus. Orthologous to human AQP3 (aquaporin 3 (Gill blood group)); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; INTERACTS WITH 1,1-dichloroethene; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AQP-2; AQP-3; aquaglyceroporin-3; aquaporin-3
Orthologs:
Homo sapiens (human) : AQP3 (aquaporin 3 (Gill blood group))  HGNC  Alliance
Rattus norvegicus (Norway rat) : Aqp3 (aquaporin 3 (Gill blood group))  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aqp3 (aquaporin 3 (Gill blood group))
Pan paniscus (bonobo/pygmy chimpanzee) : AQP3 (aquaporin 3 (Gill blood group))
Canis lupus familiaris (dog) : AQP3 (aquaporin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aqp3 (aquaporin 3 (Gill blood group))
Sus scrofa (pig) : AQP3 (aquaporin 3)
Chlorocebus sabaeus (African green monkey) : AQP3 (aquaporin 3 (Gill blood group))
Heterocephalus glaber (naked mole-rat) : Aqp3 (aquaporin 3 (Gill blood group))
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl441,092,722 - 41,098,183 (-)EnsemblGRCm38mm10GRCm38
GRCm38441,092,724 - 41,098,183 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37441,039,757 - 41,045,216 (-)NCBIGRCm37mm9NCBIm37
MGSCv36441,281,477 - 41,286,849 (-)NCBImm8
Celera440,753,580 - 40,759,039 (-)NCBICelera
Cytogenetic Map4A5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Aqp3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68639
Created: 2001-07-11
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.