Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PRKAG1 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PRKAG1 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PRKAG1 mRNA and Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PRKAG1 gene] | CTD | PMID:17942748 and PMID:28213091 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PRKAG1 mRNA | CTD | PMID:28213091 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of PRKAG1 mRNA | CTD | PMID:21570461 | 2,6-dinitrotoluene | affects expression | ISO | Prkag1 (Rattus norvegicus) | 6480464 | 2 and 6-dinitrotoluene affects the expression of PRKAG1 mRNA | CTD | PMID:21346803 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | PRKAG1 (Homo sapiens) | 6480464 | tetrabromobisphenol A results in decreased expression of PRKAG1 protein | CTD | PMID:31675489 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | PRKAG1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of PRKAG1 mRNA | CTD | PMID:28628672 | 5-aza-2'-deoxycytidine | increases expression | ISO | PRKAG1 (Homo sapiens) | 6480464 | Decitabine results in increased expression of PRKAG1 mRNA | CTD | PMID:17908484 | acrolein | multiple interactions | ISO | PRKAG1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of PRKAG1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of PRKAG1 mRNA | CTD | PMID:32699268 | aflatoxin B1 | increases methylation | ISO | PRKAG1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of PRKAG1 gene | CTD | PMID:27153756 | all-trans-retinoic acid | increases expression | ISO | PRKAG1 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of PRKAG1 mRNA | CTD | PMID:33167477 | alpha-pinene | multiple interactions | ISO | PRKAG1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of PRKAG1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of PRKAG1 mRNA | CTD | PMID:32699268 | ammonium chloride | affects expression | ISO | Prkag1 (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of PRKAG1 mRNA | CTD | PMID:16483693 | antimycin A | decreases expression | ISO | PRKAG1 (Homo sapiens) | 6480464 | Antimycin A results in decreased expression of PRKAG1 mRNA | CTD | PMID:33512557 | aristolochic acid A | decreases expression | ISO | PRKAG1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of PRKAG1 mRNA | CTD | PMID:33212167 | arsane | affects methylation | ISO | PRKAG1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of PRKAG1 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | PRKAG1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of PRKAG1 gene | CTD | PMID:25304211 | arsenite(3-) | multiple interactions | ISO | PRKAG1 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to PRKAG1 mRNA] | CTD | PMID:32406909 | azoxystrobin | decreases expression | ISO | PRKAG1 (Homo sapiens) | 6480464 | azoxystrobin results in decreased expression of PRKAG1 mRNA | CTD | PMID:33512557 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of PRKAG1 mRNA | CTD | PMID:19770486 | bisphenol A | increases methylation | ISO | Prkag1 (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of PRKAG1 gene | CTD | PMID:28505145 | bisphenol A | decreases expression | ISO | Prkag1 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of PRKAG1 mRNA | CTD | PMID:30816183 more ... | bisphenol A | decreases expression | ISO | PRKAG1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of PRKAG1 mRNA and bisphenol A results in decreased expression of PRKAG1 protein | CTD | PMID:29275510 and PMID:31675489 | Bisphenol B | increases expression | ISO | PRKAG1 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of PRKAG1 protein | CTD | PMID:34186270 | bisphenol F | multiple interactions | ISO | PRKAG1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of PRKAG1 mRNA | CTD | PMID:28628672 | bisphenol F | increases expression | ISO | PRKAG1 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of PRKAG1 protein | CTD | PMID:34186270 | butyric acid | increases expression | ISO | Prkag1 (Rattus norvegicus) | 6480464 | Butyric Acid results in increased expression of PRKAG1 mRNA | CTD | PMID:12800193 | cannabidiol | multiple interactions | ISO | PRKAG1 (Homo sapiens) | 6480464 | [Cannabidiol co-treated with moringin] results in increased expression of PRKAG1 mRNA | CTD | PMID:30096889 | CGP 52608 | multiple interactions | ISO | PRKAG1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to PRKAG1 gene] | CTD | PMID:28238834 | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of PRKAG1 mRNA | CTD | PMID:37019170 | choline | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of PRKAG1 gene | CTD | PMID:20938992 | cisplatin | increases expression | ISO | PRKAG1 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of PRKAG1 mRNA | CTD | PMID:27392435 | copper atom | multiple interactions | EXP | | 6480464 | [ATP7A gene mutant form results in increased abundance of Copper] which results in decreased expression of PRKAG1 mRNA | CTD | PMID:15467011 | copper(0) | multiple interactions | EXP | | 6480464 | [ATP7A gene mutant form results in increased abundance of Copper] which results in decreased expression of PRKAG1 mRNA | CTD | PMID:15467011 | decabromodiphenyl ether | decreases expression | ISO | PRKAG1 (Homo sapiens) | 6480464 | decabromobiphenyl ether results in decreased expression of PRKAG1 protein | CTD | PMID:31675489 | dexamethasone | multiple interactions | ISO | PRKAG1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of PRKAG1 mRNA | CTD | PMID:28628672 | dicrotophos | decreases expression | ISO | PRKAG1 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of PRKAG1 mRNA | CTD | PMID:28302478 | doxorubicin | affects expression | ISO | PRKAG1 (Homo sapiens) | 6480464 | Doxorubicin affects the expression of PRKAG1 protein | CTD | PMID:29385562 | doxorubicin | decreases expression | ISO | PRKAG1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of PRKAG1 mRNA | CTD | PMID:29803840 | elemental selenium | increases expression | ISO | PRKAG1 (Homo sapiens) | 6480464 | Selenium results in increased expression of PRKAG1 mRNA | CTD | PMID:19244175 | fenofibrate | increases expression | ISO | PRKAG1 (Homo sapiens) | 6480464 | Fenofibrate results in increased expression of PRKAG1 protein | CTD | PMID:25545733 | fenpyroximate | decreases expression | ISO | PRKAG1 (Homo sapiens) | 6480464 | fenpyroximate results in decreased expression of PRKAG1 mRNA | CTD | PMID:33512557 | flavonoids | decreases expression | ISO | Prkag1 (Rattus norvegicus) | 6480464 | Flavonoids results in decreased expression of PRKAG1 mRNA | CTD | PMID:18035473 | folic acid | multiple interactions | EXP | | 6480464 | [1 more ... | CTD | PMID:20938992 and PMID:22206623 | indometacin | multiple interactions | ISO | PRKAG1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of PRKAG1 mRNA | CTD | PMID:28628672 | ivermectin | decreases expression | ISO | PRKAG1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of PRKAG1 protein | CTD | PMID:32959892 | L-methionine | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of PRKAG1 gene | CTD | PMID:20938992 | ozone | multiple interactions | ISO | PRKAG1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of PRKAG1 mRNA more ... | CTD | PMID:32699268 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of PRKAG1 mRNA | CTD | PMID:17562736 | perfluorooctanoic acid | increases expression | EXP | | 6480464 | perfluorooctanoic acid results in increased expression of PRKAG1 protein | CTD | PMID:37422089 | phenobarbital | decreases expression | ISO | Prkag1 (Rattus norvegicus) | 6480464 | Phenobarbital results in decreased expression of PRKAG1 mRNA | CTD | PMID:19162173 and PMID:21318169 | picoxystrobin | decreases expression | ISO | PRKAG1 (Homo sapiens) | 6480464 | picoxystrobin results in decreased expression of PRKAG1 mRNA | CTD | PMID:33512557 | pregnenolone 16alpha-carbonitrile | decreases expression | ISO | Prkag1 (Rattus norvegicus) | 6480464 | Pregnenolone Carbonitrile results in decreased expression of PRKAG1 mRNA | CTD | PMID:19162173 and PMID:21318169 | rotenone | decreases expression | ISO | PRKAG1 (Homo sapiens) | 6480464 | Rotenone results in decreased expression of PRKAG1 mRNA | CTD | PMID:33512557 | selenium atom | increases expression | ISO | PRKAG1 (Homo sapiens) | 6480464 | Selenium results in increased expression of PRKAG1 mRNA | CTD | PMID:19244175 | Soman | decreases expression | ISO | Prkag1 (Rattus norvegicus) | 6480464 | Soman results in decreased expression of PRKAG1 mRNA | CTD | PMID:19281266 | tebufenpyrad | decreases expression | ISO | PRKAG1 (Homo sapiens) | 6480464 | 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in decreased expression of PRKAG1 mRNA | CTD | PMID:33512557 | tetrachloromethane | affects expression | ISO | Prkag1 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride affects the expression of PRKAG1 mRNA | CTD | PMID:12734012 | topiramate | decreases expression | ISO | Prkag1 (Rattus norvegicus) | 6480464 | topiramate results in decreased expression of PRKAG1 mRNA | CTD | PMID:16979414 | trichloroethene | increases methylation | ISO | Prkag1 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased methylation of PRKAG1 gene | CTD | PMID:27618143 | |