Cyp4x1 (cytochrome P450, family 4, subfamily x, polypeptide 1) - Rat Genome Database
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Gene: Cyp4x1 (cytochrome P450, family 4, subfamily x, polypeptide 1) Mus musculus
Analyze
Symbol: Cyp4x1
Name: cytochrome P450, family 4, subfamily x, polypeptide 1
RGD ID: 731279
MGI Page MGI
Description: Is expressed in several structures, including genitourinary system; heart; nervous system; and neural retina. Orthologous to several human genes including CYP4X1 (cytochrome P450 family 4 subfamily X member 1); INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 2,3',4,4',5-Pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A230025G20; Cyp4a2; Cyp4a28-ps; CYP_a; CYPIVX1; cytochrome P450 4X1; cytochrome P450, 4x1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394114,963,520 - 114,991,276 (-)NCBIGRCm39mm39
GRCm39 Ensembl4114,963,520 - 114,991,478 (-)Ensembl
GRCm384115,106,323 - 115,134,079 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4115,106,323 - 115,134,281 (-)EnsemblGRCm38mm10GRCm38
MGSCv374114,781,287 - 114,806,582 (-)NCBIGRCm37mm9NCBIm37
MGSCv364114,606,614 - 114,631,909 (-)NCBImm8
Celera4113,855,830 - 113,880,996 (-)NCBICelera
Cytogenetic Map4D1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11156618   PMID:11217851   PMID:12466851   PMID:12477932   PMID:15752708   PMID:16141072   PMID:16141073   PMID:16478468   PMID:18287559  
PMID:20562862   PMID:21267068   PMID:21386911   PMID:21677750   PMID:21873635   PMID:29227996  


Genomics

Comparative Map Data
Cyp4x1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394114,963,520 - 114,991,276 (-)NCBIGRCm39mm39
GRCm39 Ensembl4114,963,520 - 114,991,478 (-)Ensembl
GRCm384115,106,323 - 115,134,079 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4115,106,323 - 115,134,281 (-)EnsemblGRCm38mm10GRCm38
MGSCv374114,781,287 - 114,806,582 (-)NCBIGRCm37mm9NCBIm37
MGSCv364114,606,614 - 114,631,909 (-)NCBImm8
Celera4113,855,830 - 113,880,996 (-)NCBICelera
Cytogenetic Map4D1NCBI
CYP4X1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl147,023,669 - 47,050,751 (+)EnsemblGRCh38hg38GRCh38
GRCh38146,961,364 - 47,055,432 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37147,427,036 - 47,516,423 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36147,261,827 - 47,289,010 (+)NCBINCBI36hg18NCBI36
Build 34147,201,259 - 47,228,442NCBI
Celera145,776,425 - 45,803,552 (+)NCBI
Cytogenetic Map1p33NCBI
HuRef145,605,361 - 45,632,362 (+)NCBIHuRef
CHM1_1147,543,816 - 47,633,195 (+)NCBICHM1_1
Cyp4x1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25128,652,844 - 128,683,338 (-)NCBI
Rnor_6.0 Ensembl5133,929,532 - 133,959,447 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.05133,929,532 - 133,959,447 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05137,719,870 - 137,750,890 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45135,496,568 - 135,527,509 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15135,501,793 - 135,532,735 (-)NCBI
Celera5127,291,173 - 127,321,075 (-)NCBICelera
Cytogenetic Map5q35NCBI
LOC102010235
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546411,378,980 - 11,556,544 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546411,373,217 - 11,415,433 (-)NCBIChiLan1.0ChiLan1.0
CYP4X1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1147,676,533 - 47,703,724 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl147,676,533 - 47,703,724 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0146,322,430 - 46,349,646 (+)NCBIMhudiblu_PPA_v0panPan3
CYP4X1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1513,509,508 - 13,605,382 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11513,509,032 - 13,546,803 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
LOC101954492
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493647427,970,585 - 27,997,909 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100627093
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.16164,414,206 - 164,469,968 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26151,954,288 - 152,008,537 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CYP4X1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12085,869,402 - 85,897,215 (-)NCBI
ChlSab1.1 Ensembl2085,869,982 - 85,896,668 (-)Ensembl
LOC101706848
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248595,647,610 - 5,697,885 (-)NCBI

Position Markers
Avpr1b  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10D1UniSTS
Cytogenetic Map13D1UniSTS
Cytogenetic Map18D3UniSTS
Cytogenetic MapXF1UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map13B2UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map10A1UniSTS
Cytogenetic Map4C7UniSTS
Cytogenetic Map13C1UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map17A1UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map7F1UniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map7F2UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map10D2UniSTS
Cytogenetic Map10B5.1UniSTS
Cytogenetic Map1E4UniSTS
Cytogenetic Map7E3UniSTS
Cytogenetic Map1A2UniSTS
Cytogenetic Map3F2.1UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic MapXA1.1UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map4C3UniSTS
Cytogenetic Map18B3UniSTS
cM Map1 UniSTS
px-38e3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4D1UniSTS
Cytogenetic Map18B3UniSTS
Cytogenetic Map18D3UniSTS
Cytogenetic Map5B3UniSTS
Cytogenetic Map17B3UniSTS
Cytogenetic Map4C7UniSTS
Cytogenetic Map13C1UniSTS
Cytogenetic Map16B5UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map1H4UniSTS
Cytogenetic Map7F2UniSTS
Cytogenetic Map10D2UniSTS
Cytogenetic Map2G3UniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic MapYA1UniSTS
Cytogenetic Map11A3.2UniSTS
Cytogenetic Map3A1UniSTS
Cytogenetic Map13C3UniSTS
Cytogenetic Map1H6UniSTS
Cytogenetic Map5B2UniSTS
Cytogenetic Map19C3UniSTS
Cytogenetic Map10D1UniSTS
Cytogenetic Map10A1UniSTS
cM Map1060.0UniSTS
cM Map1106.6UniSTS
cM Map1936.5UniSTS
cM Map520.0UniSTS
cM Map1340.0UniSTS
Cyp4x1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4D1UniSTS
cM Map452.76UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156183778Mouse
4142047Mvwf3_mmodifier of von Willebrand factor 3 (mouse)Not determined14010457117215009Mouse
26884449Sklq2_mskull length QTL 2, 5 week (mouse)436700000129100000Mouse
1357895Ctrcts_mcataract severity (mouse)Not determined445709925138615442Mouse
11532714Sluc43_msusceptibility to lung cancer 43 (mouse)446642108123233418Mouse
4141900Skts-fp1_mskin tumor susceptibility in FVB and PWK 1 (mouse)Not determined453550839124161387Mouse
27095905Scvln3_msacral vertebrae length 2, 5 week (mouse)455600000129100000Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155600000Mouse
27095939Ulnl9_mulna length 9, 16 week (mouse)465400000119000000Mouse
25314312Syncl2_msynaptonemal complex length 2 (mouse)465800000146500000Mouse
27095917Scvln14_msacral vertebrae length 2, 16 week (mouse)468100000130500000Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468100000150800000Mouse
27095924Pglq2_mpelvic girdle length QTL 2, 5 week (mouse)469200000131000000Mouse
1301597Anxty_manxiety (mouse)Not determined474219337128115487Mouse
12904933Edlmmq3_mextensor digitorum longus muscle mass QTL 3 (mouse)481325754115325754Mouse
1302204Spm1_msplenomegaly modifier (mouse)Not determined482356158116356345Mouse
1301867Idd11_minsulin dependent diabetes susceptibility 11 (mouse)Not determined483747673117747809Mouse
1301556Cd4vts1_mCD4 virgin T cell subset 1 (mouse)Not determined485571641119571840Mouse
1357726Lnopy1_mlens opacity 1 (mouse)Not determined485571641119571840Mouse
1301930Papg1_mpulmonary adenoma progression 1 (mouse)Not determined485923970119924082Mouse
1301118Bbaa23_mB.burgdorferi-associated arthritis 23 (mouse)Not determined485923970119924082Mouse
27226716Metcl2_mmetatarsal-calcaneal length 2, 5 week (mouse)488200000118700000Mouse
11532738Abd1_mautoimmune biliary disease 1 (mouse)489063832116413923Mouse
4141549W10q10_mweight 10 weeks QTL 10 (mouse)Not determined89063832140740892Mouse
4141093W3q17_mweight 3 weeks QTL 17 (mouse)Not determined89063832140740892Mouse
4141623W6q13_mweight 6 weeks QTL 13 (mouse)Not determined89063832140740892Mouse
1357529Lvrq8_mliver weight QTL 8 (mouse)Not determined489063832140740892Mouse
39128212Lwq21_mliver weight QTL 21 (mouse)489063832140740892Mouse
1301823Bmd7_mbone mineral density 7 (mouse)Not determined489063832151570093Mouse
13824982Svwq1_mseminal vesicle weight QTL 1 (mouse)490000000119000000Mouse
1300918Stheal4_msoft tissue heal 4 (mouse)Not determined490112430124112550Mouse
11553870Cmmm_mcarcinoma modifier of MSM (mouse)490733471124733584Mouse
13208562Wght7_mweight 7 (mouse)491000000148000000Mouse
15039368Nmrs19_mNAFLD-associated magnetic resonance shift 19 (mouse)491025583125025583Mouse
12904002Opfaq9_mopen field activity QTL 9 (mouse)493118593127118593Mouse
1301731Cafq2_mcaffeine metabolism QTL 2 (mouse)Not determined494875058128875257Mouse
1301233Sbw2_msplenomegaly-NZB x NZW 2 (mouse)Not determined495069342128115487Mouse
1301815Sles2_msystemic lupus erythmatosus suppressor 2 (mouse)Not determined495069342150592401Mouse
1300580Lbw2_mlupus NZB x NZW 2 (mouse)Not determined498657302128115487Mouse
1301106Skts7_mskin tumor susceptibility 7 (mouse)Not determined4100214774134215009Mouse
1301847Fecq2_mfecundity QTL 2 (mouse)Not determined4100214774134215009Mouse
14696689Gdq2_mgrooming duration QTL 2, females (mouse)4101000000125000000Mouse
12880433Fgf23lq1_mFGF23 serum level QTL 1 (mouse)4101300000135300000Mouse
1300689Dob1_mDietary obesity 1 (mouse)Body weight4101717404123233418Mouse
15039377Bw45_mbody weight QTL 45 (mouse)4105812001139812001Mouse
15039378Adip30_madiposity 30 (mouse)4105812001139812001Mouse
15039382Ltgq7_mliver triglyceride QTL 7 (mouse)4105812001139812001Mouse
12910794Pwbwq8_mpost-weaning body weight QTL 8 (mouse)4105978113141706527Mouse
12910797Pwgrq4_mpre-weaning growth rate QTL 4 (mouse)4105978113141706527Mouse
12910808Pwbwq9_mpost-weaning body weight QTL 9 (mouse)4105978113141706527Mouse
12910813Pwbwq4_mpre-weaning body weight QTL 4 (mouse)4105978113141706527Mouse
1357800Tgq3_mtriglyceride QTL 3 (mouse)Not determined4107161300141161387Mouse
1300663Start2_mstartle response 2 (mouse)Not determined4107371164141371360Mouse
1300809Ccrs2_mcorpus callosum hemisphere surface size 2 (mouse)Not determined4107371164141371360Mouse
1300781Lith8_mlithogenic gene 8 (mouse)Not determined4107371164141371360Mouse
1301382Arvm2_mautoimmune renal vasculitis 2 (mouse)Not determined4107897771141897963Mouse
10755520Rbc1_mred blood cell count 1 (mouse)4108583899142583899Mouse
10755522Hgb1_mhemoglobin 1 (mouse)4108583899142583899Mouse
10755521Hct1_mhematocrit 1 (mouse)4108583899142583899Mouse
10412072Ssen1_msuseptibility to Sendai virus 1 (mouse)Not determined4109800935133427471Mouse
13208565Bmiq6_mbody mass index QTL 6 (mouse)4111000000126000000Mouse
1300839Dyscalc2_mdystrophic cardiac calcinosis 2 (mouse)Not determined4111115258145115487Mouse
1300743Skull6_mskull morphology 6 (mouse)Not determined4111115258145115487Mouse
15039385Mvlq3_mmacrovesicular liver lesion QTL 3 (mouse)4112288593146288593Mouse
4141001Tgq17_mtriglyceride QTL 17 (mouse)Not determined112629696146629696Mouse
10047132Albq19_malbuminuria QTL 19 (mouse)Not determined4112930596146930596Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:679
Count of miRNA genes:446
Interacting mature miRNAs:491
Transcripts:ENSMUST00000051400, ENSMUST00000106545
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000051400   ⟹   ENSMUSP00000059545
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl4115,108,682 - 115,133,977 (-)Ensembl
RefSeq Acc Id: ENSMUST00000106545   ⟹   ENSMUSP00000102155
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl4115,106,323 - 115,134,281 (-)Ensembl
RefSeq Acc Id: NM_001003947   ⟹   NP_001003947
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394114,963,520 - 114,991,276 (-)NCBI
GRCm384115,106,323 - 115,134,079 (-)NCBI
MGSCv374114,781,287 - 114,806,582 (-)RGD
Celera4113,855,830 - 113,880,996 (-)RGD
cM Map4 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001003947 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI13126 (Get FASTA)   NCBI Sequence Viewer  
  BAC30028 (Get FASTA)   NCBI Sequence Viewer  
  CAH10751 (Get FASTA)   NCBI Sequence Viewer  
  EDL30655 (Get FASTA)   NCBI Sequence Viewer  
  Q6A152 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001003947   ⟸   NM_001003947
- UniProtKB: Q6A152 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000059545   ⟸   ENSMUST00000051400
RefSeq Acc Id: ENSMUSP00000102155   ⟸   ENSMUST00000106545

Promoters
RGD ID:6884240
Promoter ID:EPDNEW_M5570
Type:initiation region
Name:Cyp4x1_1
Description:Mus musculus cytochrome P450, family 4, subfamily x, polypeptide1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384115,133,983 - 115,134,043EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1932403 AgrOrtholog
Ensembl Genes ENSMUSG00000047155 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000059545 UniProtKB/Swiss-Prot
  ENSMUSP00000102155 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000051400 UniProtKB/Swiss-Prot
  ENSMUST00000106545 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 1.10.630.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cyt_P450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_P450_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_P450_E_grp-I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_P450_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:81906 UniProtKB/Swiss-Prot
MGD MGI:1932403 ENTREZGENE
NCBI Gene 81906 ENTREZGENE
Pfam p450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cyp4x1 PhenoGen
PRINTS EP450I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CYTOCHROME_P450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48264 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2A9Y7_MOUSE UniProtKB/TrEMBL
  CP4X1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q2HJC6 UniProtKB/Swiss-Prot
  Q8BYS0 UniProtKB/Swiss-Prot