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Gene: Canx (calnexin) Mus musculus
Symbol: Canx
Name: calnexin
Description: Predicted to have apolipoprotein binding activity; calcium ion binding activity; and ionotropic glutamate receptor binding activity. Involved in clathrin-dependent endocytosis and synaptic vesicle endocytosis. Localizes to the endoplasmic reticulum quality control compartment and integral component of membrane. Predicted to colocalize with the rough endoplasmic reticulum. Is expressed in brain; genitourinary system; liver; and musculature. Orthologous to human CANX (calnexin); PARTICIPATES IN antigen processing and presentation pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110069N15Rik; AI988026; Cnx; D11Ertd153e
Homo sapiens (human) : CANX (calnexin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Canx (calnexin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Canx (calnexin)
Pan paniscus (bonobo/pygmy chimpanzee) : CANX (calnexin)
Canis lupus familiaris (dog) : CANX (calnexin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Canx (calnexin)
Sus scrofa (pig) : CANX (calnexin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381150,293,957 - 50,325,673 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371150,107,459 - 50,139,175 (-)NCBIGRCm37mm9NCBIm37
MGSCv361150,137,890 - 50,169,014 (-)NCBImm8
Celera1154,854,566 - 54,886,282 (-)NCBICelera
Cytogenetic Map11 B1.3NCBI
cM Map1130.46NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Canx
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 737069
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.