(-)-epigallocatechin 3-gallate increases activity ISO RGD:68468 6480464 epigallocatechin gallate results in increased activity of POR protein CTD PMID:15998352 (2,4,5-trichlorophenoxy)acetic acid decreases expression EXP 6480464 2 more ... CTD PMID:18579281 (R)-lipoic acid multiple interactions EXP 6480464 [CYP1A1 protein co-treated with CYP1A2 protein] affects the reaction [[Thioctic Acid results in decreased activity of POR protein] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]] more ... CTD PMID:21932800 (R)-lipoic acid multiple interactions ISO RGD:68468 6480464 Thioctic Acid inhibits the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid] CTD PMID:24120545 (R)-lipoic acid decreases activity ISO RGD:68468 6480464 Thioctic Acid results in decreased activity of POR protein CTD PMID:16391466 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expression ISO RGD:68335 6480464 o, p'-DDT affects the expression of POR mRNA CTD PMID:17984292 1,2,4-trimethylbenzene decreases expression ISO RGD:68335 6480464 pseudocumene results in decreased expression of POR protein CTD PMID:17337753 1,2-dimethylhydrazine increases activity ISO RGD:68335 6480464 1, 2-Dimethylhydrazine results in increased activity of POR protein CTD PMID:19497424 , PMID:29108773 1,2-dimethylhydrazine multiple interactions ISO RGD:68335 6480464 asiatic acid inhibits the reaction [1 more ... CTD PMID:19497424 , PMID:29108773 1,3-Dinitropyrene multiple interactions ISO RGD:68468 6480464 [CYP1A1 protein co-treated with POR protein] results in decreased metabolism of 1 more ... CTD PMID:11113705 1,8-Dinitropyrene multiple interactions ISO RGD:68468 6480464 [CYP1A1 protein co-treated with POR protein] results in increased metabolism of 1 more ... CTD PMID:11113705 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE increases expression ISO RGD:68335 6480464 Nevirapine metabolite results in increased expression of POR mRNA, Nevirapine results in increased expression of POR mRNA CTD PMID:23947594 17alpha-ethynylestradiol multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of POR mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of POR mRNA CTD PMID:17942748 17beta-estradiol 3-benzoate decreases expression ISO RGD:68335 6480464 estradiol 3-benzoate results in decreased expression of POR protein CTD PMID:24752506 2,2',3,3',6,6'-hexachlorobiphenyl affects metabolic processing EXP 6480464 POR protein affects the metabolism of 2 more ... CTD PMID:30729780 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO RGD:68335 6480464 2 more ... CTD PMID:20056577 , PMID:27291303 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO RGD:68468 6480464 [POR protein co-treated with CYP3A4 protein] affects the susceptibility to 2 more ... CTD PMID:27913846 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:17942748 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of POR mRNA CTD PMID:16960034 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:68468 6480464 Tetrachlorodibenzodioxin results in increased expression of POR mRNA CTD PMID:20106945 , PMID:21632981 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of POR mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:68335 6480464 Tetrachlorodibenzodioxin results in decreased expression of POR mRNA CTD PMID:21215274 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:68335 6480464 Tetrachlorodibenzodioxin affects the expression of POR mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:68335 6480464 Tetrachlorodibenzodioxin results in increased expression of POR mRNA CTD PMID:16960034 2,4-dinitrotoluene affects expression ISO RGD:68335 6480464 2, 4-dinitrotoluene affects the expression of POR mRNA CTD PMID:21346803 2,6-dichlorobenzonitrile decreases response to substance EXP 6480464 POR protein results in decreased susceptibility to dichlobanil CTD PMID:20840855 2,6-dinitrotoluene affects expression ISO RGD:68335 6480464 2, 6-dinitrotoluene affects the expression of POR mRNA CTD PMID:21346803 2-acetamidofluorene increases expression ISO RGD:68335 6480464 2-Acetylaminofluorene results in increased expression of POR mRNA CTD PMID:15089088 2-Amino-9H-pyrido[2,3-b]indole multiple interactions EXP 6480464 POR gene mutant form results in decreased metabolism of and results in increased susceptibility to 2-amino-9H-pyrido(2, 3-b)indole CTD PMID:26583703 3',5'-cyclic AMP increases expression EXP 6480464 Cyclic AMP results in increased expression of POR mRNA CTD PMID:25576683 3,3',4,4'-tetrachlorobiphenyl multiple interactions EXP 6480464 3 more ... CTD PMID:19467301 3,3'-Dichlorobenzidine affects metabolic processing ISO RGD:68335 6480464 POR protein affects the metabolism of 3, 3'-Dichlorobenzidine CTD PMID:3130202 3,4-methylenedioxymethamphetamine increases expression EXP 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of POR mRNA CTD PMID:20188158 3-Amino-1-methyl-5H-pyrido[4,3-b]indole decreases activity EXP 6480464 3-amino-1-methyl-5H-pyrido(4, 3-b)indole results in decreased activity of POR protein CTD PMID:12744663 3-Amino-1-methyl-5H-pyrido[4,3-b]indole multiple interactions EXP 6480464 3-amino-1-methyl-5H-pyrido(4, 3-b)indole promotes the reaction [purpurin results in increased activity of POR protein] CTD PMID:12744663 3-isobutyl-1-methyl-7H-xanthine multiple interactions EXP 6480464 [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of POR mRNA, [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of POR mRNA CTD PMID:16054899 , PMID:24848799 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine multiple interactions ISO RGD:68468 6480464 [CYP1A2 protein co-treated with POR protein co-treated with OAT protein] results in increased susceptibility to 2-amino-3-methylimidazo(4, 5-f)quinoline CTD PMID:10503888 , PMID:9581821 3-methylcholanthrene increases activity EXP 6480464 Methylcholanthrene results in increased activity of POR protein CTD PMID:22978700 3-methylcholanthrene increases expression EXP 6480464 Methylcholanthrene results in increased expression of POR mRNA CTD PMID:23169610 3-methylcholanthrene multiple interactions EXP 6480464 Methylcholanthrene inhibits the reaction [POR gene mutant form results in decreased expression of CYP3A11 mRNA] more ... CTD PMID:23169610 , PMID:23846873 3-Nitrofluoranthene multiple interactions ISO RGD:68468 6480464 [CYP1B1 protein co-treated with POR protein] results in decreased metabolism of 3-nitrofluoranthene CTD PMID:11113705 3H-1,2-dithiole-3-thione affects expression ISO RGD:68335 6480464 1, 2-dithiol-3-thione affects the expression of POR mRNA CTD PMID:19162173 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one affects response to substance EXP 6480464 POR affects the susceptibility to 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:22710403 4-acetylaminofluorene increases expression ISO RGD:68335 6480464 4-acetylaminofluorene results in increased expression of POR mRNA CTD PMID:15089088 4-nitroquinoline N-oxide increases activity ISO RGD:68335 6480464 4-Nitroquinoline-1-oxide results in increased activity of POR protein CTD PMID:23499697 4-nitroquinoline N-oxide multiple interactions ISO RGD:68335 6480464 geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased activity of POR protein] CTD PMID:23499697 6-propyl-2-thiouracil decreases expression ISO RGD:68335 6480464 Propylthiouracil results in decreased expression of POR mRNA CTD PMID:24780913 7,12-dimethyltetraphene multiple interactions EXP 6480464 POR protein affects the reaction [9 more ... CTD PMID:22595614 7,12-dimethyltetraphene decreases abundance EXP 6480464 POR protein results in decreased abundance of 9 more ... CTD PMID:22595614 8-hydroxy-2'-deoxyguanosine multiple interactions ISO RGD:68335 6480464 [Nitrofurazone co-treated with POR protein co-treated with Copper] results in increased abundance of 8-oxo-7-hydrodeoxyguanosine CTD PMID:15488632 9-cis,11-trans-octadecadienoic acid decreases expression EXP 6480464 cis-9, trans-11-conjugated linoleic acid results in decreased expression of POR mRNA CTD PMID:17217560 9-hydroxyellipticine multiple interactions ISO RGD:68468 6480464 [CYP3A4 protein co-treated with POR protein co-treated with NADP] results in increased chemical synthesis of 9-hydroxyellipticine CTD PMID:22390216 acetic acid increases metabolic processing ISO RGD:68335 6480464 POR protein results in increased metabolism of Acetic Acid analog CTD PMID:21933969 acetic acid increases metabolic processing ISO RGD:68468 6480464 POR protein results in increased metabolism of Acetic Acid analog CTD PMID:21933969 acetylsalicylic acid decreases expression ISO RGD:68468 6480464 Aspirin results in decreased expression of POR mRNA CTD PMID:15928584 aflatoxin B1 affects expression ISO RGD:68468 6480464 Aflatoxin B1 affects the expression of POR protein CTD PMID:20106945 aflatoxin B1 increases methylation ISO RGD:68468 6480464 Aflatoxin B1 results in increased methylation of POR gene CTD PMID:27153756 aflatoxin B1 decreases expression ISO RGD:68468 6480464 Aflatoxin B1 results in decreased expression of POR mRNA CTD PMID:27153756 aflatoxin B1 multiple interactions ISO RGD:68468 6480464 [CYP3A7 co-treated with POR] results in increased susceptibility to Aflatoxin B1, [POR protein co-treated with CYP3A4 protein] results in increased susceptibility to Aflatoxin B1 CTD PMID:27913846 , PMID:7625840 aldrin decreases expression EXP 6480464 Aldrin results in decreased expression of POR mRNA CTD PMID:18579281 all-trans-retinoic acid increases expression ISO RGD:68468 6480464 Tretinoin results in increased expression of POR mRNA CTD PMID:15498508 more ... ametryn multiple interactions ISO RGD:68468 6480464 POR protein promotes the reaction [CYP1A2 protein results in increased metabolism of ametryne] CTD PMID:8971136 amiodarone affects expression ISO RGD:68335 6480464 Amiodarone affects the expression of POR mRNA CTD PMID:18355885 amitraz increases activity ISO RGD:68335 6480464 amitraz results in increased activity of POR protein CTD PMID:15350676 amitriptyline affects expression ISO RGD:68335 6480464 Amitriptyline affects the expression of POR mRNA CTD PMID:18355885 ammonium chloride affects expression ISO RGD:68335 6480464 Ammonium Chloride affects the expression of POR mRNA CTD PMID:16483693 amphibole asbestos affects expression ISO RGD:68468 6480464 Asbestos, Amphibole affects the expression of POR protein CTD PMID:20855422 andrographolide multiple interactions EXP 6480464 [andrographolide co-treated with beta-Naphthoflavone] results in increased expression of POR mRNA CTD PMID:19737545 anthocyanin increases expression ISO RGD:68335 6480464 Anthocyanins results in increased expression of POR mRNA CTD PMID:18803703 aristolochic acid increases metabolic processing ISO RGD:68335 6480464 POR protein results in increased metabolism of aristolochic acid I CTD PMID:26845733 aristolochic acid increases metabolic processing ISO RGD:68468 6480464 POR protein results in increased metabolism of aristolochic acid I CTD PMID:26845733 aristolochic acid affects abundance EXP 6480464 POR protein affects the abundance of aristolochic acid I metabolite CTD PMID:21362632 aristolochic acid multiple interactions EXP 6480464 [CYP1A1 protein co-treated with CYP1A2 protein] affects the reaction [[Thioctic Acid results in decreased activity of POR protein] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]] more ... CTD PMID:21362632 , PMID:21932800 Aroclor 1254 increases expression ISO RGD:68335 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of POR mRNA, Chlorodiphenyl (54% Chlorine) results in increased expression of POR protein CTD PMID:18178546 , PMID:8471063 asiatic acid multiple interactions ISO RGD:68335 6480464 asiatic acid inhibits the reaction [1, 2-Dimethylhydrazine results in increased activity of POR protein] CTD PMID:29108773 astaxanthin increases expression ISO RGD:68335 6480464 astaxanthine results in increased expression of POR protein CTD PMID:21414371 astaxanthin decreases activity ISO RGD:68335 6480464 astaxanthine results in decreased activity of POR protein CTD PMID:21414371 atrazine increases expression ISO RGD:68468 6480464 Atrazine results in increased expression of POR mRNA CTD PMID:22378314 benzene increases activity ISO RGD:68335 6480464 Benzene results in increased activity of POR protein CTD PMID:3080823 benzene increases expression ISO RGD:68468 6480464 Benzene results in increased expression of POR mRNA CTD PMID:19162166 benzo[a]pyrene decreases expression ISO RGD:68468 6480464 Benzo(a)pyrene results in decreased expression of POR mRNA CTD PMID:20106945 benzo[a]pyrene multiple interactions ISO RGD:68468 6480464 [[POR protein co-treated with CYP3A4 protein] results in increased susceptibility to Benzo(a)pyrene] which results in increased mutagenesis of HPRT1 gene CTD PMID:27913846 benzo[a]pyrene affects response to substance EXP 6480464 POR protein affects the susceptibility to Benzo(a)pyrene CTD PMID:28111842 , PMID:29368147 benzo[a]pyrene multiple interactions ISO RGD:68335 6480464 [[CYP1A1 protein co-treated with POR protein co-treated with EPHX1 protein] results in increased oxidation of Benzo(a)pyrene] which results in increased abundance of benzo(a)pyrene 7 more ... CTD PMID:24530354 benzo[a]pyrene decreases response to substance EXP 6480464 POR protein results in decreased susceptibility to Benzo(a)pyrene CTD PMID:24530354 benzo[a]pyrene increases metabolic processing EXP 6480464 POR protein results in increased metabolism of Benzo(a)pyrene CTD PMID:21987461 benzo[a]pyrene increases response to substance EXP 6480464 POR protein results in increased susceptibility to Benzo(a)pyrene CTD PMID:21376747 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of POR mRNA, Benzo(a)pyrene results in increased expression of POR protein CTD PMID:19449198 , PMID:19770486 benzo[a]pyrene multiple interactions EXP 6480464 [lipopolysaccharide, E coli O55-B5 co-treated with Benzo(a)pyrene] affects the expression of POR mRNA more ... CTD PMID:19449198 more ... Benzo[a]pyrene-7,8-diol multiple interactions ISO RGD:68335 6480464 [[CYP1A1 protein co-treated with POR protein co-treated with EPHX1 protein] results in increased oxidation of Benzo(a)pyrene] which results in increased abundance of benzo(a)pyrene 7, 8-dihydrodiol CTD PMID:24530354 Benzyl viologen increases expression ISO RGD:68335 6480464 Benzyl Viologen results in increased expression of POR mRNA CTD PMID:22846377 beta-hexachlorocyclohexane increases expression EXP 6480464 beta-hexachlorocyclohexane results in increased expression of POR mRNA CTD PMID:25270620 beta-naphthoflavone multiple interactions ISO RGD:68335 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of POR mRNA more ... CTD PMID:18164116 more ... beta-naphthoflavone multiple interactions EXP 6480464 [andrographolide co-treated with beta-Naphthoflavone] results in increased expression of POR mRNA CTD PMID:19737545 bexarotene increases expression ISO RGD:68335 6480464 bexarotene results in increased expression of POR mRNA CTD PMID:16648578 bezafibrate increases activity ISO RGD:68335 6480464 Bezafibrate results in increased activity of POR protein CTD PMID:7606338 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:19850644 , PMID:28433925 bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of POR mRNA CTD PMID:19850644 bisphenol A decreases expression ISO RGD:68335 6480464 bisphenol A results in decreased expression of POR protein CTD PMID:24752506 bisphenol A increases expression ISO RGD:68468 6480464 bisphenol A results in increased expression of POR mRNA CTD PMID:29275510 bisphenol A multiple interactions ISO RGD:68468 6480464 bisphenol A promotes the reaction [POR protein binds to ESR1 protein] CTD PMID:27156127 bisphenol A multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 bisphenol A increases expression ISO RGD:68335 6480464 bisphenol A results in increased expression of POR mRNA CTD PMID:25181051 bosentan affects expression ISO RGD:68468 6480464 Bosentan affects the expression of POR mRNA CTD PMID:29761207 bromobenzene increases expression ISO RGD:68335 6480464 bromobenzene results in increased expression of POR mRNA CTD PMID:12628495 buspirone increases expression ISO RGD:68335 6480464 Buspirone results in increased expression of POR mRNA CTD PMID:24136188 C60 fullerene increases expression ISO RGD:68335 6480464 fullerene C60 results in increased expression of POR mRNA CTD PMID:19167457 cadmium dichloride multiple interactions ISO RGD:68468 6480464 diphenyleneiodonium inhibits the reaction [Cadmium Chloride results in increased activity of POR protein] CTD PMID:20934533 cadmium dichloride increases expression ISO RGD:68468 6480464 Cadmium Chloride results in increased expression of POR protein CTD PMID:24527689 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of POR mRNA CTD PMID:11958953 cadmium dichloride increases activity ISO RGD:68468 6480464 Cadmium Chloride results in increased activity of POR protein CTD PMID:20934533 capsaicin multiple interactions EXP 6480464 Capsaicin inhibits the reaction [Benzo(a)pyrene results in increased expression of POR protein] CTD PMID:19449198 carbamazepine increases expression ISO RGD:68468 6480464 Carbamazepine results in increased expression of POR mRNA CTD PMID:17112801 carbon nanotube decreases expression EXP 6480464 Nanotubes, Carbon analog results in decreased expression of POR mRNA, Nanotubes, Carbon results in decreased expression of POR mRNA CTD PMID:25554681 carbon nanotube increases expression EXP 6480464 Nanotubes, Carbon analog results in increased expression of POR mRNA CTD PMID:25620056 carvone increases response to substance EXP 6480464 POR protein results in increased susceptibility to carvone analog CTD PMID:21376747 chenodeoxycholic acid increases abundance EXP 6480464 POR gene mutant form results in increased abundance of Chenodeoxycholic Acid CTD PMID:25034404 chloroform decreases response to substance EXP 6480464 POR results in decreased susceptibility to Chloroform CTD PMID:18031782 chloroform affects response to substance EXP 6480464 POR protein affects the susceptibility to Chloroform CTD PMID:23732084 cholic acid increases expression EXP 6480464 Cholic Acid results in increased expression of POR mRNA CTD PMID:17521389 cholic acid decreases abundance EXP 6480464 POR gene mutant form results in decreased abundance of Cholic Acid CTD PMID:25034404 chrysin multiple interactions ISO RGD:68468 6480464 [CYP2A6 protein co-treated with POR protein] results in increased oxidation of chrysin CTD PMID:30964977 ciglitazone multiple interactions ISO RGD:68468 6480464 [ciglitazone binds to PPARG protein alternative form] which results in increased expression of POR mRNA, [ciglitazone binds to PPARG protein] which results in increased expression of POR mRNA CTD PMID:16197558 ciguatoxin CTX1B affects expression EXP 6480464 Ciguatoxins affects the expression of POR mRNA CTD PMID:18353800 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of POR mRNA CTD PMID:15464296 cisplatin multiple interactions ISO RGD:68468 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of POR mRNA CTD PMID:27392435 clofibrate decreases expression EXP 6480464 Clofibrate results in decreased expression of POR mRNA CTD PMID:17585979 clofibrate increases expression ISO RGD:68335 6480464 Clofibrate results in increased expression of POR mRNA, Clofibrate results in increased expression of POR protein CTD PMID:12851107 more ... clofibrate increases activity ISO RGD:68335 6480464 Clofibrate results in increased activity of POR protein CTD PMID:7606338 clofibric acid multiple interactions ISO RGD:68335 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of POR mRNA CTD PMID:17602206 clomipramine affects expression ISO RGD:68335 6480464 Clomipramine affects the expression of POR mRNA CTD PMID:18355885 cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of POR mRNA CTD PMID:21139344 copper atom multiple interactions ISO RGD:68335 6480464 [Nitrofurazone co-treated with POR protein co-treated with Copper] results in increased abundance of 8-oxo-7-hydrodeoxyguanosine CTD PMID:15488632 copper atom decreases expression ISO RGD:68335 6480464 Copper results in decreased expression of POR mRNA CTD PMID:22465980 copper atom multiple interactions ISO RGD:68468 6480464 [NSC 689534 binds to Copper] which results in increased expression of POR mRNA CTD PMID:20971185 copper(0) multiple interactions ISO RGD:68335 6480464 [Nitrofurazone co-treated with POR protein co-treated with Copper] results in increased abundance of 8-oxo-7-hydrodeoxyguanosine CTD PMID:15488632 copper(0) decreases expression ISO RGD:68335 6480464 Copper results in decreased expression of POR mRNA CTD PMID:22465980 copper(0) multiple interactions ISO RGD:68468 6480464 [NSC 689534 binds to Copper] which results in increased expression of POR mRNA CTD PMID:20971185 copper(2+) multiple interactions ISO RGD:68335 6480464 [Nitrofurazone co-treated with POR protein co-treated with Copper] results in increased abundance of 8-oxo-7-hydrodeoxyguanosine CTD PMID:15488632 copper(2+) decreases expression ISO RGD:68335 6480464 Copper results in decreased expression of POR mRNA CTD PMID:22465980 copper(2+) multiple interactions ISO RGD:68468 6480464 [NSC 689534 binds to Copper] which results in increased expression of POR mRNA CTD PMID:20971185 copper(II) sulfate decreases expression EXP 6480464 Copper Sulfate results in decreased expression of POR mRNA CTD PMID:18579281 cycloheximide multiple interactions ISO RGD:68468 6480464 POR protein mutant form promotes the reaction [Cycloheximide results in decreased expression of POR protein] CTD PMID:27496950 cycloheximide decreases expression ISO RGD:68468 6480464 Cycloheximide results in decreased expression of POR protein CTD PMID:27496950 cyclophosphamide multiple interactions ISO RGD:68468 6480464 POR promotes the reaction [CYP2B6 results in increased susceptibility to Cyclophosphamide] more ... CTD PMID:10919648 , PMID:9766669 cyclophosphamide increases expression ISO RGD:68335 6480464 Cyclophosphamide results in increased expression of POR mRNA CTD PMID:11599041 cyclosporin A decreases expression ISO RGD:68468 6480464 Cyclosporine results in decreased expression of POR mRNA CTD PMID:20106945 cyclosporin A increases expression ISO RGD:68468 6480464 Cyclosporine results in increased expression of POR mRNA CTD PMID:25562108 cyproconazole increases expression EXP 6480464 cyproconazole results in increased expression of POR mRNA CTD PMID:22334560 more ... cyproconazole increases expression ISO RGD:68335 6480464 cyproconazole results in increased expression of POR mRNA CTD PMID:29038839 cyproconazole multiple interactions ISO RGD:68335 6480464 [cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of POR mRNA, [cyproconazole co-treated with epoxiconazole] results in increased expression of POR mRNA CTD PMID:29038839 cyproconazole multiple interactions EXP 6480464 NR1I3 promotes the reaction [cyproconazole results in increased expression of POR mRNA] CTD PMID:25656644 deoxycholic acid decreases abundance EXP 6480464 POR gene mutant form results in decreased abundance of Deoxycholic Acid CTD PMID:25034404 dexamethasone multiple interactions EXP 6480464 [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of POR mRNA, [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of POR mRNA CTD PMID:16054899 , PMID:24848799 dexamethasone increases expression ISO RGD:68335 6480464 Dexamethasone results in increased expression of POR mRNA CTD PMID:20032058 dexamethasone multiple interactions ISO RGD:68335 6480464 Testosterone inhibits the reaction [Dexamethasone results in increased expression of POR mRNA] CTD PMID:20032058 dibenz[a,h]anthracene increases expression EXP 6480464 1 more ... CTD PMID:26377693 dibenziodolium multiple interactions ISO RGD:68468 6480464 diphenyleneiodonium inhibits the reaction [[POR protein results in increased metabolism of Diquat] which results in increased abundance of Hydrogen Peroxide] more ... CTD PMID:20934533 , PMID:21215309 dibenziodolium multiple interactions ISO RGD:68335 6480464 diphenyleneiodonium inhibits the reaction [POR protein affects the metabolism of Nitrofurantoin] CTD PMID:18206659 dibenziodolium multiple interactions EXP 6480464 diphenyleneiodonium inhibits the reaction [[POR protein results in increased metabolism of Diquat] which results in increased abundance of Hydrogen Peroxide] more ... CTD PMID:21215309 dibutyl phthalate decreases expression ISO RGD:68335 6480464 Dibutyl Phthalate results in decreased expression of POR mRNA CTD PMID:17379624 more ... diclofenac affects response to substance EXP 6480464 POR affects the susceptibility to Diclofenac CTD PMID:25820915 diclofenac increases oxidation EXP 6480464 POR results in increased oxidation of Diclofenac CTD PMID:25820915 dimethyl sulfoxide multiple interactions EXP 6480464 Dimethyl Sulfoxide inhibits the reaction [[POR protein results in increased metabolism of Diquat] which results in increased abundance of Hydroxyl Radical] CTD PMID:21215309 dimethyl sulfoxide multiple interactions ISO RGD:68468 6480464 Dimethyl Sulfoxide inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein] more ... CTD PMID:11368792 dimethyl sulfoxide decreases activity ISO RGD:68468 6480464 Dimethyl Sulfoxide results in decreased activity of POR protein CTD PMID:11368792 dioxygen multiple interactions ISO RGD:68468 6480464 diphenyleneiodonium inhibits the reaction [[POR protein results in increased metabolism of Diquat] which results in increased metabolism of Oxygen] more ... CTD PMID:21215309 , PMID:22545110 dioxygen increases metabolic processing ISO RGD:68468 6480464 [POR protein results in increased metabolism of Diquat] which results in increased metabolism of Oxygen, [POR protein results in increased metabolism of Paraquat] which results in increased metabolism of Oxygen CTD PMID:21215309 diquat multiple interactions ISO RGD:68468 6480464 [[Iron co-treated with POR protein] results in increased metabolism of Diquat] which results in increased abundance of Hydroxyl Radical more ... CTD PMID:21215309 diquat increases metabolic processing EXP 6480464 [POR protein results in increased metabolism of Diquat] which results in increased metabolism of NADP, POR protein results in increased metabolism of Diquat CTD PMID:21215309 diquat multiple interactions EXP 6480464 [POR protein results in increased metabolism of Diquat] which results in increased abundance of Hydrogen Peroxide more ... CTD PMID:21215309 diquat increases metabolic processing ISO RGD:68468 6480464 [POR protein results in increased metabolism of Diquat] which results in increased metabolism of NADP more ... CTD PMID:21215309 doxorubicin decreases response to substance ISO RGD:68468 6480464 POR mRNA results in decreased susceptibility to Doxorubicin CTD PMID:16322897 doxorubicin decreases expression ISO RGD:68468 6480464 Doxorubicin results in decreased expression of POR mRNA CTD PMID:29803840 doxorubicin multiple interactions ISO RGD:68468 6480464 POR protein affects the metabolism of and results in increased activity of Doxorubicin CTD PMID:15942634 elemental selenium increases expression ISO RGD:68468 6480464 Selenium results in increased expression of POR mRNA CTD PMID:19244175 ellipticine multiple interactions ISO RGD:68468 6480464 [CYP3A4 protein co-treated with POR protein co-treated with NADP] results in increased oxidation of ellipticine CTD PMID:22390216 epoxiconazole increases expression EXP 6480464 epoxiconazole results in increased expression of POR mRNA CTD PMID:22334560 epoxiconazole multiple interactions ISO RGD:68335 6480464 [cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of POR mRNA, [cyproconazole co-treated with epoxiconazole] results in increased expression of POR mRNA CTD PMID:29038839 epoxiconazole increases expression ISO RGD:68335 6480464 epoxiconazole results in increased expression of POR mRNA CTD PMID:29038839 ethanol increases expression EXP 6480464 Ethanol results in increased expression of POR mRNA CTD PMID:19167417 ethanol multiple interactions EXP 6480464 Ethanol affects the expression of and affects the splicing of POR mRNA CTD PMID:30319688 ethanol multiple interactions ISO RGD:68335 6480464 zingerone inhibits the reaction [Ethanol results in increased activity of POR protein] CTD PMID:28442378 ethanol increases activity ISO RGD:68335 6480464 Ethanol results in increased activity of POR protein CTD PMID:28442378 fenofibrate increases expression ISO RGD:68335 6480464 Fenofibrate results in increased expression of POR mRNA CTD PMID:16707586 fenofibrate increases expression ISO RGD:68468 6480464 Fenofibrate results in increased expression of POR mRNA CTD PMID:25572481 ferricyanide increases reduction ISO RGD:68335 6480464 POR protein results in increased reduction of hexacyanoferrate III CTD PMID:18678259 ferroheme b multiple interactions ISO RGD:68468 6480464 [CYB5A protein co-treated with Heme] promotes the reaction [[CYP3A4 protein co-treated with POR protein co-treated with NADP] results in increased chemical synthesis of 12-hydroxyellipticine], [CYB5A protein co-treated with Heme] promotes the reaction [[CYP3A4 protein co-treated with POR protein co-treated with NADP] results in increased chemical synthesis of 13-hydroxyellipticine] CTD PMID:22390216 fipronil increases expression ISO RGD:68468 6480464 fipronil results in increased expression of POR mRNA CTD PMID:27091632 fipronil multiple interactions ISO RGD:68468 6480464 [fipronil co-treated with DEET] results in increased expression of POR mRNA CTD PMID:27091632 fluconazole decreases expression ISO RGD:68335 6480464 Fluconazole results in decreased expression of POR mRNA CTD PMID:16643972 fluconazole multiple interactions EXP 6480464 NR1I3 promotes the reaction [Fluconazole results in increased expression of POR mRNA] CTD PMID:25656644 fluconazole increases expression EXP 6480464 Fluconazole results in increased expression of POR mRNA CTD PMID:16730040 , PMID:25656644 flusilazole increases expression ISO RGD:68335 6480464 flusilazole results in increased expression of POR mRNA CTD PMID:28263823 flutamide increases expression ISO RGD:68335 6480464 Flutamide results in increased expression of POR mRNA CTD PMID:24136188 flutamide decreases expression ISO RGD:68335 6480464 Flutamide results in decreased expression of POR mRNA CTD PMID:24793618 furan increases expression ISO RGD:68335 6480464 furan results in increased expression of POR mRNA CTD PMID:26194646 gamma-hexachlorocyclohexane increases expression ISO RGD:68335 6480464 Hexachlorocyclohexane results in increased expression of POR mRNA CTD PMID:17785943 gemfibrozil increases activity ISO RGD:68335 6480464 Gemfibrozil results in increased activity of POR protein CTD PMID:7606338 geraniol multiple interactions ISO RGD:68335 6480464 geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased activity of POR protein] CTD PMID:23499697 glycocholic acid decreases abundance EXP 6480464 POR gene mutant form results in decreased abundance of Glycocholic Acid CTD PMID:25034404 glycodeoxycholic acid increases abundance EXP 6480464 POR gene mutant form results in increased abundance of Glycodeoxycholic Acid CTD PMID:25034404 glycolithocholic acid increases abundance EXP 6480464 POR gene mutant form results in increased abundance of glycolithocholic acid CTD PMID:25034404 gold atom multiple interactions ISO RGD:68468 6480464 [Polyethyleneimine binds to Gold] which results in decreased expression of POR mRNA CTD PMID:28433809 gold(0) multiple interactions ISO RGD:68468 6480464 [Polyethyleneimine binds to Gold] which results in decreased expression of POR mRNA CTD PMID:28433809 gold(1+) multiple interactions ISO RGD:68468 6480464 [Polyethyleneimine binds to Gold] which results in decreased expression of POR mRNA CTD PMID:28433809 griseofulvin affects expression EXP 6480464 Griseofulvin affects the expression of POR mRNA CTD PMID:12735108 heme b multiple interactions ISO RGD:68468 6480464 [CYB5A protein co-treated with Heme] promotes the reaction [[CYP3A4 protein co-treated with POR protein co-treated with NADP] results in increased chemical synthesis of 12-hydroxyellipticine], [CYB5A protein co-treated with Heme] promotes the reaction [[CYP3A4 protein co-treated with POR protein co-treated with NADP] results in increased chemical synthesis of 13-hydroxyellipticine] CTD PMID:22390216 hemin multiple interactions ISO RGD:68468 6480464 Dimethyl Sulfoxide promotes the reaction [Hemin inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]] more ... CTD PMID:11368792 hemin decreases activity ISO RGD:68468 6480464 Hemin results in decreased activity of POR protein CTD PMID:11368792 hesperetin multiple interactions ISO RGD:68335 6480464 hesperetin inhibits the reaction [1, 2-Dimethylhydrazine results in increased activity of POR protein] CTD PMID:19497424 hexachlorobenzene decreases expression ISO RGD:68335 6480464 Hexachlorobenzene results in decreased expression of POR mRNA CTD PMID:15159207 hydrogen peroxide increases abundance ISO RGD:68468 6480464 POR protein results in increased abundance of Hydrogen Peroxide CTD PMID:25061110 hydrogen peroxide multiple interactions ISO RGD:68335 6480464 POR protein promotes the reaction [Vitamin K 3 results in increased chemical synthesis of Hydrogen Peroxide] CTD PMID:27558805 hydrogen peroxide multiple interactions EXP 6480464 [POR protein results in increased metabolism of Diquat] which results in increased abundance of Hydrogen Peroxide more ... CTD PMID:21215309 hydrogen peroxide increases chemical synthesis ISO RGD:68468 6480464 POR protein results in increased chemical synthesis of Hydrogen Peroxide CTD PMID:20561902 hydrogen peroxide multiple interactions ISO RGD:68468 6480464 [POR protein co-treated with 2-chloroethyl ethyl sulfide] results in increased chemical synthesis of Hydrogen Peroxide more ... CTD PMID:20561902 more ... hydroxyl multiple interactions ISO RGD:68468 6480464 [[Iron co-treated with POR protein] results in increased metabolism of Diquat] which results in increased abundance of Hydroxyl Radical more ... CTD PMID:21215309 hydroxyl multiple interactions EXP 6480464 [POR protein results in increased metabolism of Diquat] which results in increased abundance of Hydroxyl Radical more ... CTD PMID:21215309 hyperforin increases expression ISO RGD:68468 6480464 hyperforin results in increased expression of POR mRNA CTD PMID:24259679 ifosfamide multiple interactions ISO RGD:68468 6480464 POR promotes the reaction [CYP2B6 results in increased susceptibility to Ifosfamide], POR promotes the reaction [CYP2C18 results in increased susceptibility to Ifosfamide] CTD PMID:9766669 imipramine affects expression ISO RGD:68335 6480464 Imipramine affects the expression of POR mRNA CTD PMID:18355885 irinotecan increases response to substance ISO RGD:68468 6480464 POR mRNA results in increased susceptibility to Irinotecan CTD PMID:15239142 iron atom multiple interactions ISO RGD:68468 6480464 [[Iron co-treated with POR protein] results in increased metabolism of Diquat] which results in increased abundance of Hydroxyl Radical more ... CTD PMID:21215309 iron(0) multiple interactions ISO RGD:68468 6480464 [[Iron co-treated with POR protein] results in increased metabolism of Diquat] which results in increased abundance of Hydroxyl Radical more ... CTD PMID:21215309 isoniazide multiple interactions ISO RGD:68335 6480464 [Zidovudine co-treated with Isoniazid] results in decreased expression of POR mRNA, silybin inhibits the reaction [[Zidovudine co-treated with Isoniazid] results in decreased expression of POR mRNA] CTD PMID:28619387 isoniazide decreases expression ISO RGD:68335 6480464 Isoniazid results in decreased expression of POR mRNA CTD PMID:28619387 ketoconazole affects expression ISO RGD:68335 6480464 Ketoconazole affects the expression of POR mRNA CTD PMID:18355885 ketoconazole increases expression EXP 6480464 Ketoconazole results in increased expression of POR protein CTD PMID:17966066 ketoconazole multiple interactions ISO RGD:68468 6480464 Ketoconazole affects the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid] CTD PMID:24120545 kojic acid multiple interactions ISO RGD:68335 6480464 [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of POR mRNA, [Diethylnitrosamine co-treated with kojic acid] results in increased expression of POR mRNA CTD PMID:18544905 leflunomide increases expression ISO RGD:68335 6480464 leflunomide results in increased expression of POR mRNA CTD PMID:24136188 leflunomide increases expression ISO RGD:68468 6480464 leflunomide results in increased expression of POR mRNA CTD PMID:28988120 lipoic acid multiple interactions EXP 6480464 [CYP1A1 protein co-treated with CYP1A2 protein] affects the reaction [[Thioctic Acid results in decreased activity of POR protein] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]] more ... CTD PMID:21932800 lipoic acid multiple interactions ISO RGD:68468 6480464 Thioctic Acid inhibits the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid] CTD PMID:24120545 lipoic acid decreases activity ISO RGD:68468 6480464 Thioctic Acid results in decreased activity of POR protein CTD PMID:16391466 lipopolysaccharide multiple interactions ISO RGD:68468 6480464 [usnic acid co-treated with Lipopolysaccharides] results in decreased expression of POR mRNA CTD PMID:22777745 lipopolysaccharide decreases expression EXP 6480464 Lipopolysaccharides results in decreased expression of POR mRNA CTD PMID:12057914 lithocholic acid increases abundance EXP 6480464 POR gene mutant form results in increased abundance of Lithocholic Acid CTD PMID:25034404 masoprocol multiple interactions EXP 6480464 Masoprocol inhibits the reaction [POR protein affects the reaction [Benzo(a)pyrene results in increased chemical synthesis of benzo(a)pyrene-7 more ... CTD PMID:28111842 MeIQ multiple interactions ISO RGD:68468 6480464 [CYP1A2 protein co-treated with POR protein co-treated with OAT protein] results in increased susceptibility to 2-amino-3 more ... CTD PMID:10503888 , PMID:9581821 MeIQx multiple interactions ISO RGD:68468 6480464 [CYP1A2 protein co-treated with POR protein co-treated with OAT protein] results in increased susceptibility to 2-amino-3 more ... CTD PMID:10503888 , PMID:9581821 menadione increases expression ISO RGD:68468 6480464 Vitamin K 3 results in increased expression of POR mRNA CTD PMID:27558805 menadione multiple interactions ISO RGD:68335 6480464 NADP promotes the reaction [POR protein results in increased reduction of Vitamin K 3], POR protein promotes the reaction [Vitamin K 3 results in increased chemical synthesis of Hydrogen Peroxide] CTD PMID:27558805 methapyrilene increases expression ISO RGD:68335 6480464 Methapyrilene results in increased expression of POR mRNA CTD PMID:15089088 methotrexate affects expression EXP 6480464 Methotrexate affects the expression of POR mRNA CTD PMID:18502557 mitomycin C increases response to substance ISO RGD:68468 6480464 POR mRNA results in increased susceptibility to Mitomycin, POR protein results in increased susceptibility to Mitomycin CTD PMID:15239142 , PMID:21386838 mono(glucosyluronic acid)bilirubin increases abundance EXP 6480464 POR gene mutant form results in increased abundance of bilirubin glucuronate CTD PMID:25147274 N,N-diethyl-m-toluamide multiple interactions ISO RGD:68468 6480464 [fipronil co-treated with DEET] results in increased expression of POR mRNA CTD PMID:27091632 N,N-diethyl-m-toluamide increases expression ISO RGD:68468 6480464 DEET results in increased expression of POR mRNA CTD PMID:27091632 N-methyl-4-phenylpyridinium decreases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of POR protein CTD PMID:26558463 N-Nitrosodi-n-butylamine multiple interactions ISO RGD:68468 6480464 [CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to dibutylnitrosamine, [CYP2E1 protein co-treated with POR protein] results in increased susceptibility to dibutylnitrosamine CTD PMID:11035158 , PMID:11733072 N-Nitrosodi-n-propylamine multiple interactions ISO RGD:68468 6480464 [CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to N-nitroso(di-n-propyl)amine, [CYP2E1 protein co-treated with POR protein] results in increased susceptibility to N-nitroso(di-n-propyl)amine CTD PMID:11035158 , PMID:11733072 N-nitrosodiethylamine multiple interactions ISO RGD:68468 6480464 [CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to Diethylnitrosamine, [CYP2E1 protein co-treated with POR protein] results in increased susceptibility to Diethylnitrosamine CTD PMID:11035158 , PMID:11733072 N-nitrosodiethylamine multiple interactions ISO RGD:68335 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of POR mRNA more ... CTD PMID:17602206 more ... N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of POR mRNA more ... CTD PMID:15492232 more ... N-nitrosodimethylamine multiple interactions ISO RGD:68468 6480464 [CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to Dimethylnitrosamine CTD PMID:11733072 NADP zwitterion multiple interactions ISO RGD:68335 6480464 NADP affects the reaction [POR protein affects the metabolism of Nitrofurantoin], NADP promotes the reaction [POR protein results in increased reduction of Vitamin K 3] CTD PMID:18206659 , PMID:27558805 NADP zwitterion multiple interactions EXP 6480464 diphenyleneiodonium inhibits the reaction [[POR protein results in increased metabolism of Diquat] which results in increased metabolism of NADP] CTD PMID:21215309 NADP zwitterion increases metabolic processing ISO RGD:68468 6480464 [POR protein results in increased metabolism of Diquat] which results in increased metabolism of NADP, [POR protein results in increased metabolism of Paraquat] which results in increased metabolism of NADP CTD PMID:21215309 NADP zwitterion increases metabolic processing EXP 6480464 [POR protein results in increased metabolism of Diquat] which results in increased metabolism of NADP CTD PMID:21215309 NADP zwitterion multiple interactions ISO RGD:68468 6480464 [CYB5A protein co-treated with Heme] promotes the reaction [[CYP3A4 protein co-treated with POR protein co-treated with NADP] results in increased chemical synthesis of 12-hydroxyellipticine] more ... CTD PMID:20545351 more ... NADP(+) multiple interactions ISO RGD:68335 6480464 NADP affects the reaction [POR protein affects the metabolism of Nitrofurantoin], NADP promotes the reaction [POR protein results in increased reduction of Vitamin K 3] CTD PMID:18206659 , PMID:27558805 NADP(+) multiple interactions EXP 6480464 diphenyleneiodonium inhibits the reaction [[POR protein results in increased metabolism of Diquat] which results in increased metabolism of NADP] CTD PMID:21215309 NADP(+) increases metabolic processing ISO RGD:68468 6480464 [POR protein results in increased metabolism of Diquat] which results in increased metabolism of NADP, [POR protein results in increased metabolism of Paraquat] which results in increased metabolism of NADP CTD PMID:21215309 NADP(+) increases metabolic processing EXP 6480464 [POR protein results in increased metabolism of Diquat] which results in increased metabolism of NADP CTD PMID:21215309 NADP(+) multiple interactions ISO RGD:68468 6480464 [CYB5A protein co-treated with Heme] promotes the reaction [[CYP3A4 protein co-treated with POR protein co-treated with NADP] results in increased chemical synthesis of 12-hydroxyellipticine] more ... CTD PMID:20545351 more ... naphthalene decreases expression EXP 6480464 naphthalene results in decreased expression of POR protein CTD PMID:19438287 nefazodone increases expression ISO RGD:68335 6480464 nefazodone results in increased expression of POR mRNA CTD PMID:24136188 nemorubicin multiple interactions ISO RGD:68468 6480464 [CYP3A4 protein co-treated with POR protein] results in increased metabolism of methoxy-morpholinyl-doxorubicin CTD PMID:15465924 nevirapine increases expression ISO RGD:68335 6480464 Nevirapine metabolite results in increased expression of POR mRNA, Nevirapine results in increased expression of POR mRNA CTD PMID:23947594 nimesulide increases expression ISO RGD:68335 6480464 nimesulide results in increased expression of POR mRNA CTD PMID:24136188 nitrofurantoin increases metabolic processing EXP 6480464 POR protein results in increased metabolism of Nitrofurantoin CTD PMID:18206659 nitrofurantoin affects metabolic processing ISO RGD:68335 6480464 POR protein affects the metabolism of Nitrofurantoin CTD PMID:18206659 nitrofurantoin multiple interactions ISO RGD:68335 6480464 diphenyleneiodonium inhibits the reaction [POR protein affects the metabolism of Nitrofurantoin] more ... CTD PMID:18206659 , PMID:6802140 nitrofurantoin increases metabolic processing ISO RGD:68468 6480464 POR protein results in increased metabolism of Nitrofurantoin CTD PMID:18206659 nitrofurazone multiple interactions ISO RGD:68335 6480464 [Nitrofurazone co-treated with POR protein co-treated with Copper] results in increased abundance of 8-oxo-7-hydrodeoxyguanosine, Nitrofurazone inhibits the reaction [POR protein results in increased metabolism of Misonidazole] CTD PMID:15488632 , PMID:6802140 Oxadiazon increases expression EXP 6480464 oxadiazon results in increased expression of POR mRNA CTD PMID:26710982 oxycodone increases expression ISO RGD:68335 6480464 Oxycodone results in increased expression of POR mRNA CTD PMID:23439660 paclitaxel increases response to substance ISO RGD:68468 6480464 POR mRNA results in increased susceptibility to Paclitaxel CTD PMID:15239142 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of POR mRNA CTD PMID:17562736 paracetamol affects metabolic processing EXP 6480464 POR protein affects the metabolism of Acetaminophen CTD PMID:15328377 paracetamol increases expression ISO RGD:68468 6480464 Acetaminophen results in increased expression of POR mRNA CTD PMID:21420995 paracetamol increases response to substance EXP 6480464 POR protein results in increased susceptibility to Acetaminophen CTD PMID:15550675 , PMID:21376747 paracetamol increases metabolic processing EXP 6480464 POR protein results in increased metabolism of Acetaminophen CTD PMID:12566435 paracetamol increases expression ISO RGD:68335 6480464 Acetaminophen results in increased expression of POR mRNA CTD PMID:17202762 paraquat increases response to substance ISO RGD:68468 6480464 POR protein results in increased susceptibility to Paraquat CTD PMID:16495354 , PMID:29058724 paraquat increases expression ISO RGD:68335 6480464 Paraquat results in increased expression of POR mRNA CTD PMID:17935786 , PMID:22846377 paraquat increases metabolic processing ISO RGD:68468 6480464 [POR protein results in increased metabolism of Paraquat] which results in increased metabolism of NADP more ... CTD PMID:21215309 paraquat multiple interactions ISO RGD:68468 6480464 [[Iron co-treated with POR protein] results in increased metabolism of Paraquat] which results in increased abundance of Hydroxyl Radical more ... CTD PMID:21215309 , PMID:29058724 paraquat multiple interactions ISO RGD:68335 6480464 Paraquat promotes the reaction [POR protein results in increased metabolism of Misonidazole] CTD PMID:6802140 paraquat affects expression ISO RGD:68335 6480464 Paraquat affects the expression of POR mRNA CTD PMID:16854511 paraquat increases response to substance EXP 6480464 POR protein results in increased susceptibility to Paraquat CTD PMID:16495354 pentachlorophenol increases expression ISO RGD:68468 6480464 Pentachlorophenol results in increased expression of POR mRNA CTD PMID:18486366 pentobarbital increases export EXP 6480464 POR protein results in increased export of Pentobarbital CTD PMID:12697746 pentobarbital affects response to substance EXP 6480464 POR protein affects the susceptibility to Pentobarbital CTD PMID:15328377 pentobarbital increases metabolic processing EXP 6480464 POR protein results in increased metabolism of Pentobarbital CTD PMID:12566435 , PMID:12697746 perfluorobutyric acid increases expression ISO RGD:68335 6480464 perfluorobutyric acid analog results in increased expression of POR mRNA CTD PMID:21878386 perfluorodecanoic acid increases expression ISO RGD:68468 6480464 perfluorodecanoic acid results in increased expression of POR mRNA CTD PMID:23567314 perfluorododecanoic acid increases expression ISO RGD:68468 6480464 perfluorododecanoic acid results in increased expression of POR mRNA CTD PMID:23567314 perfluoroheptanoic acid increases expression ISO RGD:68468 6480464 perfluoro-n-heptanoic acid results in increased expression of POR mRNA CTD PMID:23567314 perfluorohexanesulfonic acid increases expression ISO RGD:68468 6480464 perfluorohexanesulfonic acid results in increased expression of POR mRNA CTD PMID:23567314 perfluorohexanoic acid increases expression ISO RGD:68468 6480464 perfluorohexanoic acid results in increased expression of POR mRNA CTD PMID:23567314 perfluorononanoic acid increases expression ISO RGD:68468 6480464 perfluoro-n-nonanoic acid results in increased expression of POR mRNA CTD PMID:23567314 perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 PPARA protein inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of POR mRNA] CTD PMID:20936131 perfluorooctane-1-sulfonic acid increases expression ISO RGD:68468 6480464 perfluorooctane sulfonic acid results in increased expression of POR mRNA CTD PMID:23567314 perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of POR mRNA CTD PMID:20936131 perfluorooctanoic acid affects expression EXP 6480464 perfluorooctanoic acid affects the expression of POR mRNA CTD PMID:18281256 perfluorooctanoic acid increases expression ISO RGD:68468 6480464 perfluorooctanoic acid results in increased expression of POR mRNA CTD PMID:23567314 perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of POR mRNA CTD PMID:18467677 , PMID:20936131 perfluorooctanoic acid increases expression ISO RGD:68335 6480464 perfluorooctanoic acid results in increased expression of POR mRNA CTD PMID:19162173 perfluorooctanoic acid multiple interactions EXP 6480464 PPARA protein promotes the reaction [perfluorooctanoic acid results in increased expression of POR mRNA] CTD PMID:18467677 perfluoroundecanoic acid increases expression ISO RGD:68468 6480464 perfluoro-n-undecanoic acid results in increased expression of POR mRNA CTD PMID:23567314 phenobarbital multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of POR mRNA more ... CTD PMID:15492232 more ... phenobarbital multiple interactions ISO RGD:68335 6480464 [Phenobarbital co-treated with beta-Naphthoflavone] results in increased expression of POR protein CTD PMID:30842367 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of POR mRNA, Phenobarbital results in increased expression of POR protein CTD PMID:19270015 more ... phenobarbital affects expression ISO RGD:68468 6480464 Phenobarbital affects the expression of POR mRNA CTD PMID:19159669 phenobarbital increases expression ISO RGD:68468 6480464 Phenobarbital results in increased expression of POR mRNA CTD PMID:19084549 , PMID:28541575 phenobarbital increases expression ISO RGD:68335 6480464 Phenobarbital results in increased expression of POR mRNA, Phenobarbital results in increased expression of POR protein CTD PMID:15089088 more ... phenobarbital increases activity EXP 6480464 Phenobarbital results in increased activity of POR protein CTD PMID:12051692 phenolphthalein multiple interactions EXP 6480464 Phenolphthalein inhibits the reaction [POR protein affects the reaction [Benzo(a)pyrene results in increased chemical synthesis of benzo(a)pyrene-7 more ... CTD PMID:28111842 phenytoin increases activity EXP 6480464 Phenytoin results in increased activity of POR protein CTD PMID:12051692 PhIP multiple interactions ISO RGD:68468 6480464 [CYP1A2 protein co-treated with POR protein co-treated with OAT protein] results in increased susceptibility to 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine CTD PMID:10503888 , PMID:9581821 pioglitazone increases expression ISO RGD:68335 6480464 pioglitazone results in increased expression of POR mRNA CTD PMID:16597547 piperonyl butoxide multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of POR mRNA, [Piperonyl Butoxide co-treated with Diethylnitrosamine] results in increased expression of POR mRNA CTD PMID:19690152 , PMID:20101389 piperonyl butoxide increases expression ISO RGD:68335 6480464 Piperonyl Butoxide results in increased expression of POR mRNA CTD PMID:22484513 piperonyl butoxide increases expression EXP 6480464 Piperonyl Butoxide results in increased expression of POR mRNA CTD PMID:17014948 , PMID:19690152 pirinixic acid multiple interactions ISO RGD:68468 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of POR mRNA CTD PMID:19710929 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of POR mRNA CTD PMID:17426115 more ... pirinixic acid increases expression ISO RGD:68335 6480464 pirinixic acid results in increased expression of POR mRNA CTD PMID:19162173 pirinixic acid multiple interactions EXP 6480464 PPARA protein promotes the reaction [pirinixic acid results in decreased expression of POR mRNA] CTD PMID:19850644 pregnenolone 16alpha-carbonitrile increases expression ISO RGD:68335 6480464 Pregnenolone Carbonitrile results in increased expression of POR mRNA CTD PMID:19162173 pregnenolone 16alpha-carbonitrile increases expression EXP 6480464 Pregnenolone Carbonitrile results in increased expression of POR mRNA CTD PMID:28903501 prochloraz multiple interactions ISO RGD:68335 6480464 [cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of POR mRNA CTD PMID:29038839 propiconazole increases expression EXP 6480464 propiconazole results in increased expression of POR mRNA CTD PMID:22334560 , PMID:23970803 propiconazole increases expression ISO RGD:68335 6480464 propiconazole results in increased expression of POR mRNA CTD PMID:19409404 prostaglandin F2alpha increases expression ISO RGD:68335 6480464 Dinoprost results in increased expression of POR mRNA CTD PMID:11517196 purpurin multiple interactions EXP 6480464 3-amino-1-methyl-5H-pyrido(4, 3-b)indole promotes the reaction [purpurin results in increased activity of POR protein] CTD PMID:12744663 purpurin increases activity EXP 6480464 purpurin results in increased activity of POR protein CTD PMID:12744663 quercetin decreases activity ISO RGD:68468 6480464 Quercetin results in decreased activity of POR protein CTD PMID:14633740 quercetin multiple interactions ISO RGD:68468 6480464 Quercetin inhibits the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid] CTD PMID:24120545 quercetin multiple interactions EXP 6480464 [Quercetin co-treated with Dietary Fats] affects the expression of POR mRNA CTD PMID:23359794 quercetin increases activity ISO RGD:68468 6480464 Quercetin results in increased activity of POR protein CTD PMID:15998352 resveratrol affects expression ISO RGD:68335 6480464 resveratrol affects the expression of POR mRNA CTD PMID:15748624 resveratrol multiple interactions EXP 6480464 resveratrol inhibits the reaction [POR protein affects the reaction [Benzo(a)pyrene results in increased chemical synthesis of benzo(a)pyrene-7 more ... CTD PMID:28111842 resveratrol increases expression ISO RGD:68335 6480464 resveratrol results in increased expression of POR mRNA CTD PMID:25905778 resveratrol increases expression EXP 6480464 resveratrol results in increased expression of POR protein CTD PMID:25505154 rifampicin increases activity EXP 6480464 Rifampin results in increased activity of POR protein CTD PMID:12051692 sarin decreases expression ISO RGD:68468 6480464 Sarin results in decreased expression of POR mRNA CTD PMID:19522546 sarin increases expression ISO RGD:68468 6480464 Sarin results in increased expression of POR mRNA CTD PMID:19522546 selenium atom increases expression ISO RGD:68468 6480464 Selenium results in increased expression of POR mRNA CTD PMID:19244175 sevoflurane affects expression ISO RGD:68335 6480464 sevoflurane affects the expression of POR mRNA CTD PMID:15967596 silicon dioxide increases expression EXP 6480464 Silicon Dioxide results in increased expression of POR mRNA CTD PMID:29203145 sodium arsenite decreases expression ISO RGD:68468 6480464 sodium arsenite results in decreased expression of POR mRNA CTD PMID:12760830 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of POR mRNA CTD PMID:11353140 sodium arsenite increases expression ISO RGD:68468 6480464 sodium arsenite results in increased expression of POR mRNA CTD PMID:12016162 sodium dichromate increases expression ISO RGD:68335 6480464 sodium bichromate results in increased expression of POR mRNA CTD PMID:12325037 sodium fluoride decreases expression EXP 6480464 Sodium Fluoride results in decreased expression of POR protein CTD PMID:27548804 streptozocin increases expression ISO RGD:68335 6480464 Streptozocin results in increased expression of POR mRNA CTD PMID:25905778 styrene increases metabolic processing EXP 6480464 POR protein results in increased metabolism of Styrene CTD PMID:22386858 styrene increases response to substance EXP 6480464 POR protein results in increased susceptibility to Styrene CTD PMID:22386858 styrene oxide increases chemical synthesis EXP 6480464 POR protein results in increased chemical synthesis of styrene oxide CTD PMID:22386858 Sudan I multiple interactions ISO RGD:68335 6480464 [CYP1A1 protein co-treated with POR protein] results in increased metabolism of 1-phenylazo-2-naphthol CTD PMID:24530354 superoxide multiple interactions ISO RGD:68468 6480464 [POR protein results in increased metabolism of Diquat] which results in increased abundance of Superoxides more ... CTD PMID:21215309 superoxide multiple interactions EXP 6480464 [POR protein results in increased metabolism of Diquat] which results in increased abundance of Superoxides, diphenyleneiodonium inhibits the reaction [[POR protein results in increased metabolism of Diquat] which results in increased abundance of Superoxides] CTD PMID:21215309 tacrolimus hydrate affects response to substance ISO RGD:68468 6480464 POR polymorphism affects the susceptibility to Tacrolimus CTD PMID:24113216 tamibarotene increases expression ISO RGD:68468 6480464 tamibarotene results in increased expression of POR mRNA CTD PMID:15498508 tamoxifen affects expression EXP 6480464 Tamoxifen affects the expression of POR mRNA CTD PMID:20937368 tamoxifen increases expression ISO RGD:68335 6480464 Tamoxifen results in increased expression of POR mRNA CTD PMID:15089088 taurochenodeoxycholic acid increases abundance EXP 6480464 POR gene mutant form results in increased abundance of Taurochenodeoxycholic Acid CTD PMID:25034404 taurocholic acid decreases abundance EXP 6480464 POR gene mutant form results in decreased abundance of Taurocholic Acid CTD PMID:25034404 taurodeoxycholic acid affects abundance EXP 6480464 POR gene mutant form affects the abundance of Taurodeoxycholic Acid CTD PMID:25034404 taurolithocholic acid increases abundance EXP 6480464 POR gene mutant form results in increased abundance of Taurolithocholic Acid CTD PMID:25034404 tauroursodeoxycholic acid affects abundance EXP 6480464 POR gene mutant form affects the abundance of tauroursodeoxycholic acid CTD PMID:25034404 tebuconazole increases expression EXP 6480464 tebuconazole results in increased expression of POR mRNA CTD PMID:25656644 tebuconazole multiple interactions EXP 6480464 NR1I3 promotes the reaction [tebuconazole results in increased expression of POR mRNA] CTD PMID:25656644 terbutryn multiple interactions ISO RGD:68468 6480464 POR protein promotes the reaction [CYP1A2 protein results in increased metabolism of terbutryne] CTD PMID:8971136 tert-butyl ethyl ether increases expression ISO RGD:68335 6480464 ethyl tert-butyl ether results in increased expression of POR protein CTD PMID:24090815 Tesaglitazar increases expression ISO RGD:68335 6480464 tesaglitazar results in increased expression of POR mRNA CTD PMID:21515302 testosterone multiple interactions ISO RGD:68335 6480464 Testosterone inhibits the reaction [Dexamethasone results in increased expression of POR mRNA] CTD PMID:20032058 testosterone affects metabolic processing EXP 6480464 POR protein affects the metabolism of Testosterone CTD PMID:15328377 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of POR mRNA CTD PMID:27339419 thyroxine increases expression EXP 6480464 Thyroxine results in increased expression of POR mRNA CTD PMID:23935926 tirapazamine multiple interactions ISO RGD:68468 6480464 POR protein promotes the reaction [CYP2B6 protein results in increased susceptibility to tirapazamine] CTD PMID:10919648 titanium dioxide decreases expression EXP 6480464 titanium dioxide results in decreased expression of POR mRNA CTD PMID:23557971 toluene affects expression ISO RGD:68335 6480464 Toluene affects the expression of POR mRNA CTD PMID:18653662 toluene increases activity ISO RGD:68335 6480464 Toluene results in increased activity of POR protein CTD PMID:3080823 tranylcypromine multiple interactions ISO RGD:68468 6480464 Tranylcypromine affects the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid] CTD PMID:24120545 triadimefon increases expression ISO RGD:68335 6480464 triadimefon results in increased expression of POR mRNA CTD PMID:19409404 tributylstannane increases expression EXP 6480464 tributyltin results in increased expression of POR mRNA CTD PMID:24848799 trichloroethene multiple interactions EXP 6480464 PPARA protein inhibits the reaction [Trichloroethylene results in decreased expression of POR mRNA] CTD PMID:15363585 trichostatin A affects expression ISO RGD:68468 6480464 trichostatin A affects the expression of POR mRNA CTD PMID:28542535 Triptolide multiple interactions EXP 6480464 POR protein results in increased hydroxylation of and results in decreased abundance of triptolide CTD PMID:21596114 Triptolide affects response to substance EXP 6480464 POR protein affects the susceptibility to triptolide CTD PMID:21596114 troglitazone increases expression ISO RGD:68335 6480464 troglitazone results in increased expression of POR mRNA CTD PMID:16597547 troglitazone increases expression ISO RGD:68468 6480464 troglitazone results in increased expression of POR mRNA CTD PMID:19631733 , PMID:25572481 urethane increases expression ISO RGD:68468 6480464 Urethane results in increased expression of POR mRNA CTD PMID:28818685 usnic acid multiple interactions ISO RGD:68468 6480464 [usnic acid co-treated with Lipopolysaccharides] results in decreased expression of POR mRNA CTD PMID:22777745 valdecoxib increases expression ISO RGD:68335 6480464 valdecoxib results in increased expression of POR mRNA CTD PMID:24136188 valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of POR mRNA CTD PMID:17292431 valproic acid increases expression ISO RGD:68468 6480464 Valproic Acid results in increased expression of POR mRNA CTD PMID:29154799 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of POR mRNA CTD PMID:19136453 , PMID:21427059 vinclozolin decreases expression ISO RGD:68335 6480464 vinclozolin results in decreased expression of POR mRNA CTD PMID:23034163 vitamin E increases expression ISO RGD:68468 6480464 Vitamin E results in increased expression of POR mRNA CTD PMID:19244175 warfarin affects response to substance ISO RGD:68468 6480464 POR gene SNP affects the susceptibility to Warfarin CTD PMID:27488389 zaragozic acid A increases expression EXP 6480464 squalestatin 1 results in increased expression of POR mRNA CTD PMID:27225895 zaragozic acid A increases expression ISO RGD:68335 6480464 squalestatin 1 results in increased expression of POR mRNA CTD PMID:27225895 zidovudine multiple interactions ISO RGD:68335 6480464 [Zidovudine co-treated with Isoniazid] results in decreased expression of POR mRNA, silybin inhibits the reaction [[Zidovudine co-treated with Isoniazid] results in decreased expression of POR mRNA] CTD PMID:28619387 zidovudine decreases expression ISO RGD:68335 6480464 Zidovudine results in decreased expression of POR mRNA CTD PMID:28619387 zinc atom increases expression ISO RGD:68335 6480464 Zinc deficiency results in increased expression of POR mRNA more ... CTD PMID:17074742 more ... zinc atom decreases expression ISO RGD:68335 6480464 Zinc deficiency results in decreased expression of POR mRNA CTD PMID:12672911 zinc pyrithione decreases expression ISO RGD:68468 6480464 pyrithione zinc results in decreased expression of POR mRNA CTD PMID:21424779 zinc sulfate increases expression ISO RGD:68335 6480464 Zinc Sulfate results in increased expression of POR mRNA CTD PMID:17074742 zinc(0) increases expression ISO RGD:68335 6480464 Zinc deficiency results in increased expression of POR mRNA more ... CTD PMID:17074742 more ... zinc(0) decreases expression ISO RGD:68335 6480464 Zinc deficiency results in decreased expression of POR mRNA CTD PMID:12672911 zingerone multiple interactions ISO RGD:68335 6480464 zingerone inhibits the reaction [Ethanol results in increased activity of POR protein] CTD PMID:28442378
Gene-Chemical Interaction Annotations
