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Gene: Por (P450 (cytochrome) oxidoreductase) Mus musculus
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Symbol: Por
Name: P450 (cytochrome) oxidoreductase
Description: Exhibits oxidoreductase activity. Predicted to be involved in several processes, including negative regulation of hydrolase activity; positive regulation of steroid biosynthetic process; and regulation of cartilage development. Predicted to localize to the cytosol; membrane; and mitochondrion. Human ortholog(s) of this gene implicated in Antley-Bixler syndrome and congenital adrenal hyperplasia. Is expressed in several structures, including alimentary system; limb; metanephros; nervous system; and sensory organ. Orthologous to human POR (cytochrome p450 oxidoreductase); PARTICIPATES IN aldosterone biosynthetic pathway; cortisol biosynthetic pathway; doxorubicin pharmacokinetics pathway; INTERACTS WITH (2,4,5-trichlorophenoxy)acetic acid; (R)-lipoic acid; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4933424M13Rik; CPR; CYPOR; NADH cytochrome P450 oxydoreductase; NADPH--cytochrome P450 reductase; P450R
Orthologs:
Homo sapiens (human) : POR (cytochrome p450 oxidoreductase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Por (cytochrome p450 oxidoreductase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Por (P450 (cytochrome) oxidoreductase)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100990437 (NADPH--cytochrome P450 reductase)
Canis lupus familiaris (dog) : POR (cytochrome p450 oxidoreductase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101965545 (NADPH--cytochrome P450 reductase)
Sus scrofa (pig) : POR (P450 (cytochrome) oxidoreductase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm385135,670,040 - 135,735,326 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375136,165,084 - 136,211,195 (+)NCBIGRCm37mm9NCBIm37
MGSCv365135,973,841 - 136,019,952 (+)NCBImm8
Celera5132,696,393 - 132,742,504 (+)NCBICelera
Cytogenetic Map5 G2NCBI
cM Map575.34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Por
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68469
Created: 2001-07-11
Species: Mus musculus
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.