Bcar3 (breast cancer anti-estrogen resistance 3) - Rat Genome Database

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Gene: Bcar3 (breast cancer anti-estrogen resistance 3) Mus musculus
Analyze
Symbol: Bcar3
Name: breast cancer anti-estrogen resistance 3
RGD ID: 1323277
MGI Page MGI
Description: Predicted to enable kinase binding activity and phosphotyrosine residue binding activity. Acts upstream of or within lens morphogenesis in camera-type eye and positive regulation of peptidyl-serine phosphorylation. Located in focal adhesion and membrane. Is expressed in brain; retina; submandibular gland primordium; testis; and tongue epithelium. Orthologous to human BCAR3 (BCAR3 adaptor protein, NSP family member).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI131758; AND-; AND-34; breast cancer anti-estrogen resistance protein 3; breast cancer anti-estrogen resistance protein 3 homolog; p130Cas-binding protein AND-34
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393122,213,406 - 122,323,840 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3122,087,785 - 122,323,840 (+)EnsemblGRCm39 Ensembl
GRCm383122,419,757 - 122,530,191 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3122,294,136 - 122,530,191 (+)EnsemblGRCm38mm10GRCm38
MGSCv373122,122,698 - 122,233,101 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363122,411,849 - 122,522,205 (+)NCBIMGSCv36mm8
Celera3128,819,836 - 128,930,961 (+)NCBICelera
Cytogenetic Map3G1NCBI
cM Map353.41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2-hydroxypropanoic acid  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4-hydroxynon-2-enal  (EXP)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (ISO)
acetylsalicylic acid  (ISO)
acrolein  (ISO)
adefovir pivoxil  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amphetamine  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
avobenzone  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chloroacetaldehyde  (ISO)
chloropicrin  (ISO)
chloroprene  (EXP)
chlorpyrifos  (EXP)
choline  (EXP)
chromium(6+)  (EXP)
ciguatoxin CTX1B  (EXP)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (EXP,ISO)
CU-O LINKAGE  (ISO)
cyclosporin A  (ISO)
cytarabine  (ISO)
diclofenac  (EXP)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
Enterolactone  (ISO)
fenofibrate  (ISO)
ferroheme b  (EXP)
fluoranthene  (EXP)
flutamide  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
fulvestrant  (ISO)
genistein  (EXP,ISO)
heme b  (EXP)
isobutanol  (ISO)
L-methionine  (EXP)
lipopolysaccharide  (EXP)
menadione  (ISO)
metformin  (ISO)
methylmercury chloride  (ISO)
nickel dichloride  (ISO)
nitrofen  (ISO)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
phenobarbital  (ISO)
piroxicam  (ISO)
progesterone  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenate  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (ISO)
topotecan  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
trovafloxacin  (EXP)
urethane  (ISO)
valdecoxib  (ISO)
valproic acid  (ISO)
vancomycin  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:10438950   PMID:10896938   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12517963   PMID:12520002   PMID:12904583   PMID:14610273   PMID:15489334   PMID:16141072  
PMID:16141073   PMID:18799693   PMID:19103205   PMID:19365570   PMID:21262352   PMID:21267068   PMID:21654156   PMID:21677750   PMID:21873635   PMID:22801373   PMID:23341629   PMID:27364350  
PMID:38414524  


Genomics

Comparative Map Data
Bcar3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393122,213,406 - 122,323,840 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3122,087,785 - 122,323,840 (+)EnsemblGRCm39 Ensembl
GRCm383122,419,757 - 122,530,191 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3122,294,136 - 122,530,191 (+)EnsemblGRCm38mm10GRCm38
MGSCv373122,122,698 - 122,233,101 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363122,411,849 - 122,522,205 (+)NCBIMGSCv36mm8
Celera3128,819,836 - 128,930,961 (+)NCBICelera
Cytogenetic Map3G1NCBI
cM Map353.41NCBI
BCAR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38193,561,741 - 93,848,151 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl193,561,741 - 93,847,150 (-)EnsemblGRCh38hg38GRCh38
GRCh37194,027,298 - 94,312,775 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36193,799,936 - 93,919,973 (-)NCBINCBI36Build 36hg18NCBI36
Build 34193,739,371 - 93,859,223NCBI
Celera192,281,411 - 92,401,455 (-)NCBICelera
Cytogenetic Map1p22.1NCBI
HuRef192,148,818 - 92,431,346 (-)NCBIHuRef
CHM1_1194,142,284 - 94,427,714 (-)NCBICHM1_1
T2T-CHM13v2.0193,407,475 - 93,693,898 (-)NCBIT2T-CHM13v2.0
Bcar3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82213,209,907 - 213,323,305 (+)NCBIGRCr8
mRatBN7.22210,525,260 - 210,638,674 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2210,525,260 - 210,638,798 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2218,201,286 - 218,314,077 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02216,109,048 - 216,221,848 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02210,952,480 - 211,065,400 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02226,563,050 - 226,679,449 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2226,563,050 - 226,679,438 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02245,929,016 - 246,041,127 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42219,075,206 - 219,188,344 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12219,044,367 - 219,151,409 (+)NCBI
Celera2202,953,635 - 203,067,717 (+)NCBICelera
Cytogenetic Map2q42NCBI
Bcar3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955423991,057 - 1,105,033 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955423991,046 - 1,105,033 (+)NCBIChiLan1.0ChiLan1.0
BCAR3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21133,177,830 - 133,455,341 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11132,490,296 - 132,610,504 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0196,230,498 - 96,508,028 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1194,960,969 - 95,104,869 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl194,960,966 - 95,080,565 (-)Ensemblpanpan1.1panPan2
BCAR3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1655,276,300 - 55,525,246 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl655,347,955 - 55,525,246 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha658,076,009 - 58,232,203 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0655,743,759 - 55,899,988 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl655,764,481 - 55,899,985 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1655,423,562 - 55,579,644 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0655,408,217 - 55,564,415 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0655,861,300 - 56,017,521 (+)NCBIUU_Cfam_GSD_1.0
Bcar3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405058103,285,698 - 103,399,549 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365375,548,422 - 5,662,219 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BCAR3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4123,440,571 - 123,666,598 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14123,440,571 - 123,666,603 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24135,115,751 - 135,322,614 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BCAR3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12039,399,818 - 39,679,686 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2039,566,157 - 39,680,660 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603378,358,639 - 78,653,780 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bcar3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247423,948,910 - 4,067,761 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247423,934,971 - 4,067,691 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Bcar3
3743 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:112
Count of miRNA genes:94
Interacting mature miRNAs:107
Transcripts:ENSMUST00000029766
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316504164130163649Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330067588147304689Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337174862143353183Mouse
26884382Bzwq1_mbi-zygomatic width QTL 1, 5 week (mouse)352207421137205761Mouse
25314313Syncl1_msynaptonemal complex length 1 (mouse)367907333128393649Mouse
1357583Sle18_msystematic lupus erythematosus susceptibility 18 (mouse)Not determined387208904125316236Mouse
4142178Ctrq2_mC. trachomatis resistance QTL 2 (mouse)Not determined389139967137453008Mouse
10766455Sle22_msystematic lupus erythematosus susceptibility 22 (mouse)390376936124377072Mouse
14747001Mancz4_mmandible centroid size 4 (mouse)390378017124378017Mouse
1302052Etohcta4_methanol conditioned taste aversion 4 (mouse)Not determined391000105125008748Mouse
1301349Pgia26_mproteoglycan induced arthritis 26 (mouse)Not determined392251533126251650Mouse
27226732Tibmd3_mtibia midshaft diameter 3, 10 week (mouse)396607316147805636Mouse
10043955Wt10q4_mbody weight, 10 weeks, QTL 4 (mouse)Not determined398624041132624197Mouse
11533920Mvb3_mmodifier of vibrator 3 (mouse)398635284132635383Mouse
12792984Modn1_mmodifier of Dstn neovascularization 1 (mouse)398635284132635383Mouse
1302114Tbs1_mtuberculosis severity 1 (mouse)Not determined398924105132924250Mouse
1300752Ap6q_malcohol preference 6 QTL (mouse)Not determined3100372912147045722Mouse
26884419Bzwq6_mbi-zygomatic width QTL 6, 10 week (mouse)3100607316137205761Mouse
27226733Tibmd6_mtibia midshaft diameter 6, 16 week (mouse)3101307316149805637Mouse
1301805Mors2_mmodifier of obesity related sterility 2 (mouse)Not determined3103482659137482783Mouse
8655599Cia5c_mcollagen induced arthritis QTL 5c (mouse)Not determined3107376936125316237Mouse
1302093Orgwq5_morgan weight QTL 5 (mouse)Not determined3107376936147304689Mouse
1300619Cdcs1_mcytokine deficiency colitis susceptibility 1 (mouse)Not determined3109834882143835005Mouse
12910793Pwbwq7_mpost-weaning body weight QTL 7 (mouse)3110084357135715812Mouse
12910796Pwbwq6_mpost-weaning body weight QTL 6 (mouse)3110084357135715812Mouse
12910815Ogrq1_moverall growth rate QTL 1 (mouse)3110084357135715812Mouse
1301381Bomb1_mbone marrow pre-B 1 (mouse)Not determined3111133243145133417Mouse
1301100Bdt2_mbone density traits 2 (mouse)Not determined3114736617148736784Mouse
10043919Afpq8_mabdominal fat percent QTL 8 (mouse)Not determined3119057332153057456Mouse
1558868Ses9_msalmonella enteritidis susceptibility 9 (mouse)Not determined3119057332153057456Mouse
4141935Tgq15_mtriglyceride QTL 15 (mouse)Not determined119318586153318586Mouse
4142449Tgq14_mtriglyceride QTL 14 (mouse)Not determined119318586153318586Mouse
1302151Lprm2_mlymphoproliferation modifier 2 (mouse)Not determined3119778857153779044Mouse
10412240Alpq6_malcohol preference QTL 6 (mouse)Not determined3120772078154772078Mouse
12903998Cfq3_mconditioned fear QTL 3 (mouse)3122188811127220016Mouse

Markers in Region
AI131758  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383122,530,022 - 122,530,111UniSTSGRCm38
MGSCv373122,232,940 - 122,233,029UniSTSGRCm37
Celera3128,930,800 - 128,930,889UniSTS
Cytogenetic Map3G3UniSTS
Whitehead/MRC_RH31386.31UniSTS
Bcar3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map3G3UniSTS
cM Map353.41UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000029766   ⟹   ENSMUSP00000029766
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3122,213,427 - 122,323,840 (+)Ensembl
GRCm38.p6 Ensembl3122,419,778 - 122,530,191 (+)Ensembl
RefSeq Acc Id: ENSMUST00000196134
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3122,087,785 - 122,220,797 (+)Ensembl
GRCm38.p6 Ensembl3122,294,136 - 122,427,148 (+)Ensembl
RefSeq Acc Id: ENSMUST00000197073   ⟹   ENSMUSP00000142469
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3122,277,372 - 122,302,097 (+)Ensembl
GRCm38.p6 Ensembl3122,483,723 - 122,508,448 (+)Ensembl
RefSeq Acc Id: ENSMUST00000197590
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3122,213,472 - 122,265,250 (+)Ensembl
GRCm38.p6 Ensembl3122,419,823 - 122,471,601 (+)Ensembl
RefSeq Acc Id: ENSMUST00000197956
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3122,301,713 - 122,306,398 (+)Ensembl
GRCm38.p6 Ensembl3122,508,064 - 122,512,749 (+)Ensembl
RefSeq Acc Id: ENSMUST00000197959
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3122,318,295 - 122,319,054 (+)Ensembl
GRCm38.p6 Ensembl3122,524,646 - 122,525,405 (+)Ensembl
RefSeq Acc Id: ENSMUST00000198659   ⟹   ENSMUSP00000143112
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3122,304,778 - 122,306,586 (+)Ensembl
GRCm38.p6 Ensembl3122,511,129 - 122,512,937 (+)Ensembl
RefSeq Acc Id: ENSMUST00000199344   ⟹   ENSMUSP00000143711
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3122,305,871 - 122,316,859 (+)Ensembl
GRCm38.p6 Ensembl3122,512,222 - 122,523,210 (+)Ensembl
RefSeq Acc Id: ENSMUST00000199358   ⟹   ENSMUSP00000142340
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3122,298,324 - 122,302,098 (+)Ensembl
GRCm38.p6 Ensembl3122,504,675 - 122,508,449 (+)Ensembl
RefSeq Acc Id: ENSMUST00000200544
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3122,213,406 - 122,220,515 (+)Ensembl
GRCm38.p6 Ensembl3122,419,757 - 122,426,866 (+)Ensembl
RefSeq Acc Id: NM_001355264   ⟹   NP_001342193
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393122,277,218 - 122,323,840 (+)NCBI
GRCm383122,483,569 - 122,530,191 (+)NCBI
Sequence:
RefSeq Acc Id: NM_013867   ⟹   NP_038895
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393122,213,406 - 122,323,840 (+)NCBI
GRCm383122,419,757 - 122,530,191 (+)NCBI
MGSCv373122,122,698 - 122,233,101 (+)RGD
Celera3128,819,836 - 128,930,961 (+)RGD
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006501559   ⟹   XP_006501622
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393122,305,536 - 122,323,832 (+)NCBI
GRCm383122,511,885 - 122,530,183 (+)NCBI
Sequence:
RefSeq Acc Id: NP_038895   ⟸   NM_013867
- Peptide Label: isoform 1
- UniProtKB: Q3TNC9 (UniProtKB/Swiss-Prot),   Q3UP10 (UniProtKB/Swiss-Prot),   Q9QZK2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006501622   ⟸   XM_006501559
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001342193   ⟸   NM_001355264
- Peptide Label: isoform 2
RefSeq Acc Id: ENSMUSP00000143112   ⟸   ENSMUST00000198659
RefSeq Acc Id: ENSMUSP00000142469   ⟸   ENSMUST00000197073
RefSeq Acc Id: ENSMUSP00000029766   ⟸   ENSMUST00000029766
RefSeq Acc Id: ENSMUSP00000143711   ⟸   ENSMUST00000199344
RefSeq Acc Id: ENSMUSP00000142340   ⟸   ENSMUST00000199358
Protein Domains
Ras-GEF   SH2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9QZK2-F1-model_v2 AlphaFold Q9QZK2 1-820 view protein structure

Promoters
RGD ID:6833493
Promoter ID:MM_KWN:35980
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:UC008REQ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv363122,122,521 - 122,123,021 (+)MPROMDB
RGD ID:6847733
Promoter ID:MM_ACW:33162
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Liver,   MEF_B6
Transcripts:BCAR3.ESEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv363122,186,391 - 122,186,891 (+)MPROMDB
RGD ID:6847731
Promoter ID:MM_ACW:33165
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Liver,   Lung
Transcripts:BCAR3.DSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv363122,215,116 - 122,215,616 (+)MPROMDB
RGD ID:6882256
Promoter ID:EPDNEW_M4579
Type:initiation region
Name:Bcar3_1
Description:Mus musculus breast cancer anti-estrogen resistance 3 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M4580  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm383122,419,779 - 122,419,839EPDNEW
RGD ID:6882258
Promoter ID:EPDNEW_M4580
Type:multiple initiation site
Name:Bcar3_2
Description:Mus musculus breast cancer anti-estrogen resistance 3 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M4579  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm383122,419,993 - 122,420,053EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1352501 AgrOrtholog
Ensembl Genes ENSMUSG00000028121 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000029766 ENTREZGENE
  ENSMUST00000029766.9 UniProtKB/Swiss-Prot
  ENSMUST00000197073.2 UniProtKB/TrEMBL
  ENSMUST00000198659.2 UniProtKB/TrEMBL
  ENSMUST00000199344.2 UniProtKB/TrEMBL
  ENSMUST00000199358.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.840.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ras_GEF_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RASGEF_cat_dom UniProtKB/Swiss-Prot
  RASGEF_cat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2_SHEP1/BCAR3/NSP1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:29815 UniProtKB/Swiss-Prot
MGD MGI:1352501 ENTREZGENE
NCBI Gene 29815 ENTREZGENE
PANTHER BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 3 HOMOLOG-LIKE PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR14247:SF10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RasGEF UniProtKB/Swiss-Prot
  SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Bcar3 PhenoGen
PRINTS SH2DOMAIN UniProtKB/TrEMBL
PROSITE RASGEF_CAT UniProtKB/Swiss-Prot
  SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RasGEF UniProtKB/Swiss-Prot
  SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48366 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55550 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JDE7_MOUSE UniProtKB/TrEMBL
  A0A0G2JDR4_MOUSE UniProtKB/TrEMBL
  A0A0G2JFC0_MOUSE UniProtKB/TrEMBL
  A0A0G2JGV2_MOUSE UniProtKB/TrEMBL
  BCAR3_MOUSE UniProtKB/Swiss-Prot
  Q3TNC9 ENTREZGENE
  Q3UP10 ENTREZGENE
  Q9QZK2 ENTREZGENE
UniProt Secondary Q3TNC9 UniProtKB/Swiss-Prot
  Q3UP10 UniProtKB/Swiss-Prot