Gnmt (glycine N-methyltransferase) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Gnmt (glycine N-methyltransferase) Mus musculus
Analyze
Symbol: Gnmt
Name: glycine N-methyltransferase
RGD ID: 10671
MGI Page MGI
Description: Enables glycine N-methyltransferase activity and glycine binding activity. Involved in S-adenosylmethionine metabolic process and protein homotetramerization. Acts upstream of or within several processes, including glycogen metabolic process; one-carbon metabolic process; and regulation of gluconeogenesis. Predicted to be part of methyltransferase complex. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; integumental system; limb; sensory organ; and skeleton. Used to study glycine N-methyltransferase deficiency and hepatocellular carcinoma. Human ortholog(s) of this gene implicated in glycine N-methyltransferase deficiency. Orthologous to human GNMT (glycine N-methyltransferase).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: glycine N methyl transferase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391747,036,590 - 47,040,091 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1747,036,590 - 47,040,094 (-)EnsemblGRCm39 Ensembl
GRCm381746,725,664 - 46,729,211 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1746,725,664 - 46,729,168 (-)EnsemblGRCm38mm10GRCm38
MGSCv371746,862,613 - 46,866,114 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361746,188,855 - 46,192,356 (-)NCBIMGSCv36mm8
Celera1750,161,350 - 50,164,841 (-)NCBICelera
Cytogenetic Map17CNCBI
cM Map1722.9NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
1,1-dichloroethene  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2,6-di-tert-butyl-4-methylphenol  (ISO)
2-nitrofluorene  (ISO)
2-palmitoylglycerol  (ISO)
3-chloropropane-1,2-diol  (ISO)
3-methylcholanthrene  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-methyltetrahydrofolic acid  (ISO)
acetamide  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (EXP,ISO)
aflatoxin M1  (ISO)
aflatoxin Q1  (ISO)
all-trans-retinoic acid  (EXP)
ammonium chloride  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bromobenzene  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
captan  (EXP)
carbon nanotube  (EXP)
chloroprene  (EXP)
cisplatin  (ISO)
clofibrate  (EXP)
clothianidin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
DDE  (ISO)
dexamethasone  (ISO)
dicrotophos  (ISO)
diquat  (EXP)
elemental selenium  (ISO)
endosulfan  (ISO)
enzalutamide  (ISO)
ethanol  (ISO)
fenofibrate  (ISO)
fenthion  (EXP)
finasteride  (ISO)
flavonoids  (ISO)
flutamide  (ISO)
folic acid  (EXP,ISO)
fructose  (EXP)
fumonisin B1  (EXP)
furan  (ISO)
gefitinib  (EXP)
genistein  (EXP,ISO)
glafenine  (ISO)
gliotoxin  (ISO)
GW 4064  (EXP)
indometacin  (ISO)
Lasiocarpine  (ISO)
leflunomide  (ISO)
MeIQx  (ISO)
metformin  (ISO)
methapyrilene  (ISO)
methidathion  (EXP)
methyl methanesulfonate  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (ISO)
N-Nitrosopyrrolidine  (ISO)
naphthalene  (EXP)
nefazodone  (ISO)
nimesulide  (ISO)
nitrofen  (ISO)
Nutlin-3  (ISO)
O-methyleugenol  (ISO)
ochratoxin A  (ISO)
ozone  (EXP,ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
phenformin  (ISO)
phenobarbital  (ISO)
PhIP  (ISO)
picoxystrobin  (ISO)
piperonyl butoxide  (ISO)
pirinixic acid  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
quercetin  (ISO)
rotenone  (ISO)
selenium atom  (ISO)
senecionine  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
streptozocin  (ISO)
sulindac  (ISO)
tebuconazole  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
triazines  (EXP)
trichloroethene  (EXP,ISO)
triphenyl phosphate  (ISO)
Triptolide  (EXP)
troglitazone  (ISO)
urethane  (ISO)
valdecoxib  (ISO)
vancomycin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Searching QTL by gene expression: analysis of diabesity. Brown AC, etal., BMC Genet 2005 Mar 10;6(1):12.
2. A review of methionine dependency and the role of methionine restriction in cancer growth control and life-span extension. Cavuoto P and Fenech MF, Cancer Treat Rev. 2012 Oct;38(6):726-36. doi: 10.1016/j.ctrv.2012.01.004. Epub 2012 Feb 17.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. S-adenosylmethionine in liver health, injury, and cancer. Lu SC and Mato JM, Physiol Rev. 2012 Oct;92(4):1515-42. doi: 10.1152/physrev.00047.2011.
5. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
6. MGDs mouse GO annotations MGD data from the GO Consortium
7. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
11. Mouse MP Annotation Import Pipeline RGD automated import pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9497905   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11130978   PMID:12477932   PMID:12748967   PMID:14681479   PMID:15340920   PMID:15489334   PMID:15939374   PMID:16141072  
PMID:16141073   PMID:16779654   PMID:17901120   PMID:17937387   PMID:18318442   PMID:18554416   PMID:19035462   PMID:19345238   PMID:19582817   PMID:20473876   PMID:21267068   PMID:21519551  
PMID:21873635   PMID:22183894   PMID:22264868   PMID:22392635   PMID:22687285   PMID:23505042   PMID:23922098   PMID:24219143   PMID:24607226   PMID:24687756   PMID:25531568   PMID:25535034  
PMID:25754535   PMID:27716281   PMID:28205209   PMID:29416626   PMID:29725048   PMID:29891549   PMID:31470507   PMID:32951289   PMID:34702858   PMID:37047834  


Genomics

Comparative Map Data
Gnmt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391747,036,590 - 47,040,091 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1747,036,590 - 47,040,094 (-)EnsemblGRCm39 Ensembl
GRCm381746,725,664 - 46,729,211 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1746,725,664 - 46,729,168 (-)EnsemblGRCm38mm10GRCm38
MGSCv371746,862,613 - 46,866,114 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361746,188,855 - 46,192,356 (-)NCBIMGSCv36mm8
Celera1750,161,350 - 50,164,841 (-)NCBICelera
Cytogenetic Map17CNCBI
cM Map1722.9NCBI
GNMT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38642,960,754 - 42,963,880 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl642,960,754 - 42,963,880 (+)EnsemblGRCh38hg38GRCh38
GRCh37642,928,492 - 42,931,618 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36643,036,478 - 43,039,596 (+)NCBINCBI36Build 36hg18NCBI36
Build 34643,036,477 - 43,039,595NCBI
Celera644,480,758 - 44,483,869 (+)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef642,645,801 - 42,648,911 (+)NCBIHuRef
CHM1_1642,930,969 - 42,934,095 (+)NCBICHM1_1
T2T-CHM13v2.0642,789,900 - 42,793,018 (+)NCBIT2T-CHM13v2.0
Gnmt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8921,752,235 - 21,756,368 (+)NCBIGRCr8
mRatBN7.2914,254,675 - 14,258,028 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl914,254,675 - 14,258,434 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx922,837,543 - 22,840,774 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0927,901,607 - 27,904,956 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0926,200,917 - 26,204,148 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0916,565,274 - 16,568,626 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl916,565,225 - 16,568,627 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0915,471,889 - 15,475,241 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4910,127,092 - 10,130,444 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1910,124,413 - 10,127,766 (+)NCBI
Celera912,003,123 - 12,006,473 (+)NCBICelera
Cytogenetic Map9q12NCBI
Gnmt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554378,944,047 - 8,946,642 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554378,944,288 - 8,946,642 (+)NCBIChiLan1.0ChiLan1.0
GNMT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2557,453,015 - 57,462,242 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1653,326,193 - 53,342,571 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0642,550,631 - 42,554,385 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1643,846,560 - 43,849,679 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl643,846,560 - 43,849,679 (+)Ensemblpanpan1.1panPan2
GNMT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11211,500,363 - 11,503,075 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1211,500,392 - 11,503,481 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1211,527,380 - 11,530,090 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01211,981,562 - 11,984,272 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1211,981,589 - 11,984,224 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11211,509,980 - 11,512,694 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01211,594,281 - 11,596,795 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01211,688,299 - 11,691,025 (+)NCBIUU_Cfam_GSD_1.0
Gnmt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494646,995,031 - 46,998,424 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647616,957,270 - 16,965,346 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647616,961,734 - 16,965,487 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GNMT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl738,038,358 - 38,041,217 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1738,038,359 - 38,041,218 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2743,486,726 - 43,489,585 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GNMT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11729,196,142 - 29,199,728 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1729,196,321 - 29,198,947 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604443,019,849 - 43,022,686 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Gnmt
110 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:348
Count of miRNA genes:260
Interacting mature miRNAs:284
Transcripts:ENSMUST00000002846, ENSMUST00000147112
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301331Lbw1_mlupus NZB x NZW 1 (mouse)Not determined171841835752420983Mouse
26884379Skwq5_mskull length QTL 5, 5 week (mouse)173311897454107028Mouse
1301840Ssial4_msusceptibility to sialadenitiss 4 (mouse)Not determined171817541252178214Mouse
1300885Mbis4_mMycobacterium bovis-induced systemic lupus erythematosus 4 (mouse)Not determined173517581770165926Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17397489048866091Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17485475247885665Mouse
1300703Uvbi2_mUVB induced immunosuppression 2 (mouse)Not determined172862240662622654Mouse
1300995Fembrs4_mfemur breaking strength 4 (mouse)Not determined171506165249061760Mouse
15039348Nmrs37_mNAFLD-associated magnetic resonance shift 37 (mouse)172781520961815209Mouse
4141357Mrdq1_mmodifier of retinal degeneration QTL 1 (mouse)Not determined3098790348039703Mouse
1301056Pas2_mpulmonary adenoma susceptibility 2 (mouse)Not determined171842214152424327Mouse
26884428Cvht3_mcranial vault height 3, 5 week (mouse)174651092682407429Mouse
4141478Hbnr7_mHeligmosomoides bakeri nematode resistance 7 (mouse)Not determined4305118551739122Mouse
1302152Skull25_mskull morphology 25 (mouse)Not determined171681972150819843Mouse
1301454Eae5_msusceptibility to experimental allergic encephalomyelitis 5 (mouse)Not determined172461275058612864Mouse
10755514Amzn2_manatomical modifier of Zfp423 2 (mouse)173596629469966424Mouse
15039354Nmrs36_mNAFLD-associated magnetic resonance shift 36 (mouse)171914502553145025Mouse
1300914Pcir4_mperiosteal circumference 4 (mouse)Not determined171506165249061760Mouse
13452396Leusq3_mleucocytosis susceptibility QTL 3 (mouse)171746220851462345Mouse
10755525Lymph2_mlymphocyte differential 2 (mouse)173880562672805626Mouse
13452399Leusq6_mleucocytosis susceptibility QTL 6 (mouse)171746220851462345Mouse
1300592Pcyts5_mplasmacytoma susceptibility 5 (mouse)Not determined173871288772712970Mouse
1300535Char3_mP. chabaudi malaria resistance QTL 3 (mouse)Not determined171746220851462345Mouse
4140955Plgr1_mplague resistance locus 1 (mouse)Not determined3103350065033630Mouse
1302070Tbbmd7_mtotal body bone mineral density 7 (mouse)Not determined171506165249061760Mouse
1302005Loco2_mlocomotor activity 2 (mouse)Not determined172688497260885114Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined485475265637357Mouse
10412214Sxbq3_mSGC/Knj cross B6 QTL 3 (mouse)Not determined171746220851462345Mouse
10755534Lymph4_mlymphocyte differential 4 (mouse)173880562672805626Mouse
10412083Sm2_msusceptibility to Schistosoma mansoni infection 2 (mouse)Not determined171702994351030078Mouse
1302140Wta4_mweight adult 4 (mouse)Not determined171681972150819843Mouse
1558758Kcal2_mkilocalorie 2 (mouse)Not determined172640101252911704Mouse
1558886Lgth9_mbody length 9 (mouse)Not determined171506165249061760Mouse
10412204Bbaa29_mB.burgdorferi-associated arthritis 29 (mouse)Not determined172605118560051352Mouse
12904951Smmq2_msoleus muscle mass QTL 2 (mouse)173678974370789743Mouse
4141319Hmtb8_mhemostasis and thrombosis rebleeding time 8 (mouse)Not determined4053444774534623Mouse
10412198Sst5_msusceptibility to tuberculosis 5 (mouse)Not determined172507658355712970Mouse
26884386Skwq13_mskull length QTL 13, 16 week (mouse)174371089153107028Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
11081168Tir7_mtrypanosome infection response 7 (mouse)171412337248123496Mouse
12903997Cfq4_mconditioned fear QTL 4 (mouse)174501655249366402Mouse
15039324Nmrs48_mNAFLD-associated magnetic resonance shift 48 (mouse)174093918774939187Mouse
26884390Skwq9_mskull length QTL 9, 10 week (mouse)174371089167806995Mouse
1300589Myaa2_mmodifier of Yaa 2 (mouse)Not determined173013255564132666Mouse

Markers in Region
AI132582  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381746,725,261 - 46,725,511UniSTSGRCm38
MGSCv371746,862,210 - 46,862,460UniSTSGRCm37
Celera1750,160,947 - 50,161,197UniSTS
Cytogenetic Map17CUniSTS
cM Map1710.0UniSTS
Whitehead/MRC_RH17562.06UniSTS
Gnmt  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17CUniSTS
cM Map1710.0UniSTS
Gnmt  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17CUniSTS
cM Map1710.0UniSTS


Sequence


Ensembl Acc Id: ENSMUST00000002846   ⟹   ENSMUSP00000002846
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1747,036,590 - 47,040,094 (-)Ensembl
GRCm38.p6 Ensembl1746,725,664 - 46,729,168 (-)Ensembl
Ensembl Acc Id: ENSMUST00000147112
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1747,036,590 - 47,037,727 (-)Ensembl
GRCm38.p6 Ensembl1746,725,664 - 46,726,801 (-)Ensembl
Ensembl Acc Id: ENSMUST00000233086
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1747,036,689 - 47,037,628 (-)Ensembl
GRCm38.p6 Ensembl1746,725,763 - 46,726,702 (-)Ensembl
RefSeq Acc Id: NM_001364890   ⟹   NP_001351819
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391747,036,590 - 47,040,091 (-)NCBI
GRCm381746,725,664 - 46,729,165 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001413152   ⟹   NP_001400081
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391747,036,590 - 47,040,091 (-)NCBI
RefSeq Acc Id: NM_010321   ⟹   NP_034451
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391747,036,590 - 47,040,091 (-)NCBI
GRCm381746,725,664 - 46,729,165 (-)NCBI
MGSCv371746,862,613 - 46,866,114 (-)RGD
Celera1750,161,350 - 50,164,841 (-)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_182115
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391747,036,590 - 47,040,091 (-)NCBI
RefSeq Acc Id: NP_034451   ⟸   NM_010321
- Peptide Label: isoform 1
- UniProtKB: Q91WN7 (UniProtKB/Swiss-Prot),   Q9QXF8 (UniProtKB/Swiss-Prot),   Q5I0T9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001351819   ⟸   NM_001364890
- Peptide Label: isoform 2
- UniProtKB: Q5I0T9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000002846   ⟸   ENSMUST00000002846
RefSeq Acc Id: NP_001400081   ⟸   NM_001413152
- Peptide Label: isoform 3
- UniProtKB: Q5I0T9 (UniProtKB/TrEMBL)
Protein Domains
Methyltransferase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9QXF8-F1-model_v2 AlphaFold Q9QXF8 1-293 view protein structure

Promoters
RGD ID:13676254
Promoter ID:EPDNEW_M22276
Type:multiple initiation site
Name:Gnmt_1
Description:Mus musculus glycine N-methyltransferase , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381746,729,165 - 46,729,225EPDNEW
RGD ID:6828190
Promoter ID:MM_KWN:23671
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Liver,   Lung,   Spleen
Transcripts:OTTMUST00000065250
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361746,863,391 - 46,864,322 (-)MPROMDB
RGD ID:6828188
Promoter ID:MM_KWN:23672
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   Spleen
Transcripts:OTTMUST00000065249
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361746,865,841 - 46,866,807 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1202304 AgrOrtholog
Ensembl Genes ENSMUSG00000002769 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000002846 ENTREZGENE
  ENSMUST00000002846.9 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glycine N-methyltransferase, chain A, domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Gly/Sar_N_MeTrfase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Methyltranfer_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14711 UniProtKB/Swiss-Prot
MGD MGI:1202304 ENTREZGENE
NCBI Gene 14711 ENTREZGENE
PANTHER GLYCINE N-METHYLTRANSFERASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR16458 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Methyltransf_31 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gnmt PhenoGen
PIRSF Gly_N-mtase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE SAM_GNMT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt GNMT_MOUSE UniProtKB/Swiss-Prot
  Q5I0T9 ENTREZGENE, UniProtKB/TrEMBL
  Q91WN7 ENTREZGENE
  Q9QXF8 ENTREZGENE
UniProt Secondary Q91WN7 UniProtKB/Swiss-Prot