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Gene: Gnmt (glycine N-methyltransferase) Mus musculus
Symbol: Gnmt
Name: glycine N-methyltransferase
RGD ID: 10671
Description: Exhibits glycine N-methyltransferase activity and glycine binding activity. Involved in several processes, including glycogen metabolic process; protein homotetramerization; and regulation of gluconeogenesis. Predicted to localize to cytosol. Is expressed in several structures, including integumental system; limb; nose; pancreas tip epithelium; and skeleton. Used to study glycine N-methyltransferase deficiency and hepatocellular carcinoma. Human ortholog(s) of this gene implicated in glycine N-methyltransferase deficiency. Orthologous to human GNMT (glycine N-methyltransferase); PARTICIPATES IN dihydropyrimidine dehydrogenase deficiency pathway; dimethylglycine dehydrogenase deficiency pathway; folate mediated one-carbon metabolic pathway; INTERACTS WITH 1,1-dichloroethene; 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: glycine N methyl transferase
Homo sapiens (human) : GNMT (glycine N-methyltransferase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gnmt (glycine N-methyltransferase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gnmt (glycine N-methyltransferase)
Pan paniscus (bonobo/pygmy chimpanzee) : GNMT (glycine N-methyltransferase)
Canis lupus familiaris (dog) : GNMT (glycine N-methyltransferase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101964621 (glycine N-methyltransferase)
Sus scrofa (pig) : GNMT (glycine N-methyltransferase)
Chlorocebus sabaeus (African green monkey) : GNMT (glycine N-methyltransferase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1746,725,664 - 46,729,168 (-)EnsemblGRCm38mm10GRCm38
GRCm381746,725,664 - 46,729,211 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371746,862,613 - 46,866,114 (-)NCBIGRCm37mm9NCBIm37
MGSCv361746,188,855 - 46,192,356 (-)NCBImm8
Celera1750,161,350 - 50,164,841 (-)NCBICelera
Cytogenetic Map17CNCBI
cM Map1722.9NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Gnmt
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10671
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.