Rbp2 (retinol binding protein 2, cellular) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Rbp2 (retinol binding protein 2, cellular) Mus musculus
Analyze
Symbol: Rbp2
Name: retinol binding protein 2, cellular
RGD ID: 11226
MGI Page MGI
Description: Predicted to have retinol binding activity. Predicted to be involved in retinoid metabolic process. Predicted to localize to cytosol. Is expressed in embryo; intestine; lower jaw tooth; and tooth. Orthologous to human RBP2 (retinol binding protein 2); PARTICIPATES IN retinol metabolic pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cellular retinol-binding protein II; Cr; Crbp; Crbp-2; CRBP-II; CrbpII; MGC159254; MGC159256; Rbp; Rbp-2; retinol-binding protein 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39998,372,590 - 98,391,824 (+)NCBIGRCm39mm39
GRCm38998,490,537 - 98,509,771 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl998,486,115 - 98,509,781 (+)EnsemblGRCm38mm10GRCm38
MGSCv37998,390,956 - 98,410,190 (+)NCBIGRCm37mm9NCBIm37
MGSCv36998,299,905 - 98,319,089 (+)NCBImm8
Celera998,036,063 - 98,055,300 (+)NCBICelera
Cytogenetic Map9E3.3NCBI
cM Map951.37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytosol  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:1849812   PMID:1966045   PMID:1981995   PMID:2170099   PMID:7601910   PMID:7613029   PMID:8100460   PMID:8268655   PMID:8288643   PMID:8397079   PMID:8631847   PMID:8748389  
PMID:9022057   PMID:9169087   PMID:9241280   PMID:10349636   PMID:10487743   PMID:10725366   PMID:10753524   PMID:10971621   PMID:11022035   PMID:11042159   PMID:11076861   PMID:12016134  
PMID:12138113   PMID:12477932   PMID:15766748   PMID:16141072   PMID:16141073   PMID:17270348   PMID:17374359   PMID:18295589   PMID:18348983   PMID:19968565   PMID:21267068   PMID:21788502  
PMID:22222225   PMID:24005908   PMID:25255718   PMID:27537484   PMID:28874522   PMID:28970247   PMID:31848688   PMID:32195347   PMID:32325033  


Genomics

Comparative Map Data
Rbp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39998,372,590 - 98,391,824 (+)NCBIGRCm39mm39
GRCm38998,490,537 - 98,509,771 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl998,486,115 - 98,509,781 (+)EnsemblGRCm38mm10GRCm38
MGSCv37998,390,956 - 98,410,190 (+)NCBIGRCm37mm9NCBIm37
MGSCv36998,299,905 - 98,319,089 (+)NCBImm8
Celera998,036,063 - 98,055,300 (+)NCBICelera
Cytogenetic Map9E3.3NCBI
cM Map951.37NCBI
RBP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3139,452,884 - 139,480,747 (-)EnsemblGRCh38hg38GRCh38
GRCh383139,452,884 - 139,476,516 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373139,171,726 - 139,199,662 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363140,654,416 - 140,678,042 (-)NCBINCBI36hg18NCBI36
Build 343140,654,424 - 140,678,050NCBI
Celera3137,594,686 - 137,618,327 (-)NCBI
Cytogenetic Map3q23NCBI
HuRef3136,547,188 - 136,570,833 (-)NCBIHuRef
CHM1_13139,135,301 - 139,158,940 (-)NCBICHM1_1
Rbp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08106,479,253 - 106,527,726 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8106,503,504 - 106,527,711 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08105,945,338 - 105,969,565 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48103,665,461 - 103,685,771 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18103,684,970 - 103,705,027 (+)NCBI
Celera898,493,627 - 98,513,957 (+)NCBICelera
Cytogenetic Map8q31NCBI
RH 3.4 Map81052.2RGD
Rbp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555086,111,168 - 6,136,010 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555086,111,558 - 6,135,929 (+)NCBIChiLan1.0ChiLan1.0
RBP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13144,089,322 - 144,112,840 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3144,089,322 - 144,112,840 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03136,488,536 - 136,513,337 (-)NCBIMhudiblu_PPA_v0panPan3
RBP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2335,619,221 - 35,642,213 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12335,619,215 - 35,642,249 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Rbp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365401,547,406 - 1,571,374 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RBP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1380,320,931 - 80,407,355 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11380,321,024 - 80,346,032 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21387,988,050 - 88,013,085 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RBP2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11551,077,753 - 51,102,110 (+)NCBI
ChlSab1.1 Ensembl1551,078,169 - 51,102,249 (+)Ensembl
Rbp2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473016,018,142 - 16,060,179 (-)NCBI

Position Markers
Rbp2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9E3.3UniSTS
cM Map957.0UniSTS
D9Mit211  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Celera998,035,491 - 98,035,615UniSTS
Cytogenetic Map9E3.3UniSTS
cM Map949.0UniSTS
Whitehead Genetic943.7UniSTS
D9Mit211.1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38998,489,768 - 98,489,956UniSTSGRCm38
MGSCv37998,390,187 - 98,390,375UniSTSGRCm37
Celera998,035,268 - 98,035,456UniSTS
Cytogenetic Map9E3.3UniSTS
cM Map949.0UniSTS
cM Map9 UniSTS
Whitehead Genetic943.7UniSTS
D9Mit211.3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38998,490,164 - 98,490,306UniSTSGRCm38
MGSCv37998,390,583 - 98,390,725UniSTSGRCm37
Celera998,035,690 - 98,035,832UniSTS
Cytogenetic Map9E3.3UniSTS
cM Map949.0UniSTS
cM Map9 UniSTS
Whitehead Genetic943.7UniSTS
D9Kyo1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9E3.3UniSTS
cM Map957.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142042Alpq3_malcohol preference QTL 3 (mouse)Not determined93739490198819654Mouse
4141224Dxmod_mdoxorubicin nephropathy modifier (mouse)Not determined49541121101528921Mouse
1301241Renf1_mrenal failure 1 (mouse)Not determined95212317899910428Mouse
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959990000109260000Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63332429120362868Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63332429120362868Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963332429120362868Mouse
1301636Lith5_mlithogenic gene 5 (mouse)Not determined966207024100207122Mouse
10045638Heal29_mwound healing/regeneration 29 (mouse)Not determined967124167101124167Mouse
1357610Vtbt8_mvertebral trabecular bone trait 8 (mouse)Not determined968897510102897652Mouse
1301924Bmd10_mbone mineral density 10 (mouse)Not determined968897510102897652Mouse
1301302Pas4_mpulmonary adenoma susceptibility 4 (mouse)Not determined969239845103239920Mouse
10412174Habiir4_mhyperoxic acute lung injury imprinted region 4 (mouse)Not determined96936046598819654Mouse
1301621Hpic1_mhaloperidol-induced catalepsy 1 (mouse)Not determined969546513103546645Mouse
1301573Etohcta8_methanol conditioned taste aversion 8 (mouse)Not determined972977005106977152Mouse
10054068El8_mepilepsy 8 (mouse)Not determined972977005106977152Mouse
1301725Lifespan1_mlife span 1 (mouse)Not determined974368177108368325Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975775364114474379Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975775364114474379Mouse
1301869Tbbmd4_mtotal body bone mineral density 4 (mouse)Not determined976117105101528921Mouse
1301407Rapop2_mradiation-induced apoptosis 2 (mouse)Not determined976535936110536130Mouse
1301192Skts6_mskin tumor susceptibility 6 (mouse)Not determined978640645112640755Mouse
10401247Bglu14_mblood glucose level 14 (mouse)Not determined979397810113397888Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981798268115798392Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982910333116910428Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982910333116910428Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982910333116910428Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984528818118528921Mouse
10412180Msam3_mmuscle, skeletal, activity measure 3 (mouse)Not determined985897510108641186Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986230401120230530Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986239845120289624Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986748483120748483Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987800000121800000Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989284925123284925Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989412277123412396Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989563342123563342Mouse
1357657Pymr_mPlasmodium yoelli malaria resistance (mouse)Not determined989977005118938021Mouse
12910770Splic1_mspleen iron content 1 (mouse)991413879124595110Mouse
12910772Lvic6_mliver iron content 6 (mouse)991413879124595110Mouse
12910773Splic3_mspleen iron content 3 (mouse)991413879124595110Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991641084124595110Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991641084124595110Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991641084124595110Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991641084124595110Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991641084124595110Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991641084124595110Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991683173124595110Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991683173124595110Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991683173124595110Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993762590124595110Mouse
1301484Bwq6_mbody weight (mouse)Not determined993762590124595110Mouse
14746992Manh67_mmandible shape 67 (mouse)994036768124595110Mouse
11081166Psl5_mpromotion susceptibility QTL 5 (mouse)994981301112872929Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996917590124595110Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:161
Count of miRNA genes:147
Interacting mature miRNAs:153
Transcripts:ENSMUST00000035029
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000035029   ⟹   ENSMUSP00000035029
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl998,490,537 - 98,509,771 (+)Ensembl
RefSeq Acc Id: ENSMUST00000187905   ⟹   ENSMUSP00000140630
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl998,486,166 - 98,509,651 (+)Ensembl
RefSeq Acc Id: ENSMUST00000188779
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl998,491,697 - 98,498,858 (+)Ensembl
RefSeq Acc Id: ENSMUST00000189446   ⟹   ENSMUSP00000140676
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl998,486,115 - 98,509,781 (+)Ensembl
RefSeq Acc Id: NM_009034   ⟹   NP_033060
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39998,372,590 - 98,391,824 (+)NCBI
GRCm38998,490,537 - 98,509,771 (+)ENTREZGENE
MGSCv37998,390,956 - 98,410,190 (+)RGD
Celera998,036,063 - 98,055,300 (+)RGD
cM Map9 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_033060   ⟸   NM_009034
- UniProtKB: Q08652 (UniProtKB/Swiss-Prot),   Q059R7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000035029   ⟸   ENSMUST00000035029
RefSeq Acc Id: ENSMUSP00000140630   ⟸   ENSMUST00000187905
RefSeq Acc Id: ENSMUSP00000140676   ⟸   ENSMUST00000189446
Protein Domains
FABP

Promoters
RGD ID:8670544
Promoter ID:EPDNEW_M13296
Type:initiation region
Name:Rbp2_1
Description:Mus musculus retinol binding protein 2, cellular , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38998,490,555 - 98,490,615EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97877 AgrOrtholog
Ensembl Genes ENSMUSG00000032454 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000035029 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000140630 UniProtKB/Swiss-Prot
  ENSMUSP00000140676 UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000035029 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000187905 UniProtKB/Swiss-Prot
  ENSMUST00000189446 UniProtKB/Swiss-Prot
Gene3D-CATH 2.40.128.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Calycin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Fatty_acid-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ILBP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lipocln_cytosolic_FA-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:19660 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:97877 ENTREZGENE
NCBI Gene 19660 ENTREZGENE
PANTHER PTHR11955 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Lipocalin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rbp2 PhenoGen
PRINTS FATTYACIDBP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE FABP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50814 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt Q059R7 ENTREZGENE, UniProtKB/TrEMBL
  Q08652 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q9D1N1 UniProtKB/Swiss-Prot